Chromatine/Épigénétique
Les inhibiteurs de la chromatine/épigénétique sont des composés qui modulent la structure et la fonction de la chromatine ou interfèrent avec les modifications épigénétiques, telles que la méthylation de l'ADN et la modification des histones. Ces inhibiteurs sont des outils essentiels pour étudier la régulation de l'expression génique et le rôle de l'épigénétique dans des maladies telles que le cancer, les troubles neurologiques et les anomalies du développement. En ciblant les processus épigénétiques, ces inhibiteurs peuvent modifier les schémas d'expression génique et offrir de nouvelles perspectives thérapeutiques. Chez CymitQuimica, nous offrons une large sélection d'inhibiteurs de la chromatine/épigénétique de haute qualité pour soutenir vos recherches en biologie moléculaire, génétique et épigénétique.
Sous-catégories appartenant à la catégorie "Chromatine/Épigénétique"
2613 produits trouvés pour "Chromatine/Épigénétique"
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1-benzyl-2-ethyl-4,5,6,7-tetrahydro-1H-indol-4-one
CAS :1-benzyl-2-ethyl-4,5,6,7-tetrahydro-1H-indol-4-one is an inhibitor Bromodomain-containing protein 4 (human).Formule :C17H19NODegré de pureté :99.08%Couleur et forme :SolidMasse moléculaire :253.34Ref: TM-T8601
1mg58,00€5mg116,00€10mg172,00€25mg281,00€50mg396,00€100mg537,00€200mg712,00€1mL*10mM (DMSO)109,00€GSK620
CAS :GSK620, a selective pan-BD2 inhibitor, has anti-inflammatory properties and favorable oral pharmacokinetics.Formule :C18H19N3O3Degré de pureté :99.42% - 99.88%Couleur et forme :SolidMasse moléculaire :325.36Ref: TM-T9020
2mg34,00€5mg49,00€10mg73,00€25mg136,00€50mg212,00€100mg314,00€200mg467,00€1mL*10mM (DMSO)87,00€Talazoparib
CAS :Talazoparib (LT-673) is a new-type PARP inhibitor (IC50: 0.58 nM), It similarly binds to PARP1/2 (Kis: 1.2/0.85 nM).Formule :C19H14F2N6ODegré de pureté :97.02% - 99.92%Couleur et forme :SolidMasse moléculaire :380.35Ref: TM-T6253
2mg42,00€5mg62,00€10mg88,00€25mg135,00€50mg187,00€100mg311,00€200mg429,00€500mg697,00€1mL*10mM (DMSO)67,00€Solcitinib
CAS :Solcitinib (GLPG-0778), a JAK1 inhibitor, may treat psoriasis, ulcerative colitis, and lupus.
Formule :C22H23N5O2Degré de pureté :99.61% - 99.82%Couleur et forme :SolidMasse moléculaire :389.45Dbet57
CAS :dBET57: PROTAC-based BRD4BD1 degrader, DC50/5h at 500 nM, ineffective on BRD4BD2.Formule :C34H31ClN8O5SDegré de pureté :99.36% - 99.52%Couleur et forme :SolidMasse moléculaire :699.18Ref: TM-T5440
1mg47,00€5mg92,00€10mg147,00€25mg264,00€50mg409,00€100mg592,00€500mg1.224,00€1mL*10mM (DMSO)166,00€MAT2A inhibitor 4
CAS :MAT2A Inhibitor 4 acts as an inhibitor targeting the catalytic subunit of methionine S-adenosyltransferase-2 (MAT2A), offering potential utility in cancerFormule :C16H15ClFNDegré de pureté :99.17%Couleur et forme :SolidMasse moléculaire :275.75Ref: TM-T9262
1mg40,00€5mg90,00€10mg131,00€25mg220,00€50mg314,00€100mg426,00€200mg575,00€1mL*10mM (DMSO)89,00€Mivebresib
CAS :Mivebresib (ABBV-075) is a potent BET inhibitor with antitumor effects, disrupting gene expression and MYC, TMPRSS2-ETS proteins.Formule :C22H19F2N3O4SDegré de pureté :98.74% - 99.32%Couleur et forme :SolidMasse moléculaire :459.47Ref: TM-T3712
1mg55,00€2mg78,00€5mg92,00€10mg150,00€25mg244,00€50mg437,00€100mg625,00€1mL*10mM (DMSO)94,00€PHA-680632
CAS :PHA-680632 is potent inhibitor of Aurora A, Aurora B and Aurora C with IC50 of 27 nM, 135 nM and 120 nM, respectively.Formule :C28H35N7O2Degré de pureté :98.2%Couleur et forme :SolidMasse moléculaire :501.623-Aminobenzamide
CAS :3-Aminobenzamide (PARP-IN-1) is an effective inhibitor of PARP (IC50<50 nM in CHO cells) and a mediator of oxidant-induced myocyte dysfunction duringFormule :C7H8N2ODegré de pureté :98.4% - 99.5%Couleur et forme :White To Off-White PowderMasse moléculaire :136.15SF2523
CAS :SF2523 is a highly selective and potent inhibitor.Formule :C19H17NO5SDegré de pureté :99.1% - 99.51%Couleur et forme :SolidMasse moléculaire :371.41Ref: TM-T3986
1mg34,00€5mg74,00€10mg113,00€25mg260,00€50mg409,00€100mg605,00€500mg1.288,00€1mL*10mM (DMSO)82,00€JNJ-64619178
CAS :JNJ-64619178: selective, oral, pseudo-irreversible PRMT5 inhibitor (IC50: 0.14 nM), effective in lung cancer.Formule :C22H23BrN6O2Degré de pureté :98.86% - 99.98%Couleur et forme :SolidMasse moléculaire :483.36Ref: TM-T15624
1mg84,00€5mg167,00€10mg260,00€25mg537,00€50mg893,00€100mg1.571,00€1mL*10mM (DMSO)172,00€GeA-69
CAS :GeA-69 (GeA69) is a selective and allosteric PARP14 macrodomain 2 (MD2) inhibitor (Kd: 0.86 μM in ITC assays).Formule :C20H16N2ODegré de pureté :99.85%Couleur et forme :SolidMasse moléculaire :300.35TTK21
CAS :TTK21 is an activator of CBP/p300 histone acetyltransferase activity.Formule :C17H15ClF3NO2Degré de pureté :98.43%Couleur et forme :SolidMasse moléculaire :357.75Ref: TM-T8778
1mg57,00€5mg105,00€10mg158,00€25mg308,00€50mg462,00€100mg692,00€500mg1.404,00€1mL*10mM (DMSO)114,00€PX-478
CAS :PX-478 is a HIF-1α inhibitor with selectivity, oral activity, and blood-brain barrier permeability.Formule :C13H20Cl4N2O3Degré de pureté :97% - 99.79%Couleur et forme :SolidMasse moléculaire :394.12Ref: TM-T6961
1mg39,00€5mg84,00€10mg130,00€25mg193,00€50mg261,00€100mg411,00€200mg605,00€1mL*10mM (DMSO)84,00€LW6
CAS :LW6 (HIF-1α inhibitor) is a novel HIF-1 inhibitor.Formule :C26H29NO5Degré de pureté :98.1% - 98.22%Couleur et forme :SolidMasse moléculaire :435.51Ref: TM-T3494
2mg44,00€5mg65,00€10mg94,00€25mg173,00€50mg281,00€100mg424,00€500mg888,00€1mL*10mM (DMSO)65,00€Dehydrocorydaline
CAS :1.Formule :C22H24NO4Degré de pureté :99.84%Couleur et forme :SolidMasse moléculaire :366.43Ref: TM-T5S2358
1mg49,00€2mg69,00€5mg105,00€10mg137,00€25mg197,00€50mg295,00€100mg447,00€1mL*10mM (DMSO)116,00€Belzutifan
CAS :"Belzutifan (MK-6482) is an oral HIF-2α inhibitor for ccRCC, with enhanced potency (IC50: 9 nM)."Formule :C17H12F3NO4SDegré de pureté :99.34% - 99.88%Couleur et forme :SolidMasse moléculaire :383.34Ref: TM-T16679
1mg66,00€5mg144,00€10mg205,00€25mg389,00€50mg625,00€100mg888,00€200mg1.198,00€1mL*10mM (DMSO)158,00€I-BET151
CAS :I-BET151 (GSK1210151A) (GSK1210151A) is a specific BET inhibitor for BRD2/3/4 (IC50: 0.5/0.25/0.79 μM, in cell-free assays).Formule :C23H21N5O3Degré de pureté :97.34% - 99.63%Couleur et forme :SolidMasse moléculaire :415.44Ref: TM-T2120
1mg48,00€2mg65,00€5mg96,00€10mg115,00€25mg202,00€50mg339,00€100mg507,00€500mg1.130,00€1mL*10mM (DMSO)105,00€Veliparib
CAS :Veliparib (ABT-888) (ABT-888) is an orally bioavailable inhibitor of PARP (Kis: 5.2/2.9 nM for PARP1/2). It enhances apoptosis and autophagy.Formule :C13H16N4ODegré de pureté :98.66% - 99%Couleur et forme :SolidMasse moléculaire :244.29Ref: TM-T2591
5mg54,00€10mg77,00€25mg120,00€50mg195,00€100mg314,00€200mg512,00€500mg807,00€1mL*10mM (DMSO)60,00€Tranylcypromine hemisulfate
CAS :Tranylcypromine hemisulfate (Tranylcypromine Sulfate) is an inhibitor of monoamine oxidase (MAO) and lysine-specific demethylase 1 (LSD1) with a rapid onset ofFormule :C9H11N1H2SO4Degré de pureté :98% - 99.96%Couleur et forme :SolidMasse moléculaire :182.23SGI-1027
CAS :SGI-1027 (DNA Methyltransferase Inhibitor II) is an effective and selective inhibitor of DNA methyltransferase (DNMT).Formule :C27H23N7ODegré de pureté :99.45% - 99.78%Couleur et forme :SolidMasse moléculaire :461.52Ref: TM-T1904
5mg58,00€10mg94,00€25mg163,00€50mg296,00€100mg467,00€500mg1.035,00€1mL*10mM (DMSO)74,00€GSK467
CAS :GSK467 is a potent and selective inhibitor of KDM5 (JARID1)(Ki : 10 nM).Formule :C17H13N5O2Degré de pureté :99.55% - 99.85%Couleur et forme :SolidMasse moléculaire :319.32MG 149
CAS :MG 149 (Tip60 HAT inhibitor) is a selective and potent Tip60 inhibitor with IC50 of 74 uM, similar potentcy for MOF(IC50= 47 uM).Formule :C22H28O3Degré de pureté :98.69% - 99.86%Couleur et forme :SolidMasse moléculaire :340.46Ref: TM-T6584
1mg50,00€2mg71,00€5mg90,00€10mg167,00€25mg308,00€50mg492,00€100mg708,00€1mL*10mM (DMSO)108,00€UNC3866
CAS :UNC3866 is a potent antagonist of the CBX7-H3 interaction as determined by AlphaScreen.Formule :C43H66N6O8Degré de pureté :88.06% - 99.62%Couleur et forme :SolidMasse moléculaire :795.02GW779439X
CAS :GW779439X is an inhibitor of CDK.Formule :C22H21F3N8Degré de pureté :97.87%Couleur et forme :SolidMasse moléculaire :454.45Ref: TM-T8866
1mg58,00€2mg82,00€5mg113,00€10mg178,00€25mg404,00€50mg592,00€100mg845,00€1mL*10mM (DMSO)124,00€CCT241736
CAS :CCT241736 is an orally bioavailable dual FLT3/Aurora kinase inhibitor that also inhibits clinically relevant FLT3-resistant mutants including FLT3-ITD and FLT3Formule :C22H23Cl2N7Degré de pureté :96.2% - 99.81%Couleur et forme :SolidMasse moléculaire :456.37G244-LM
CAS :G244-LM is a potent and specific inhibitor of tankyrase 1/2. G244-LM inhibits Wnt signaling.Formule :C18H22N4O3S2Degré de pureté :98.46%Couleur et forme :SolidMasse moléculaire :406.52AMG 900
CAS :AMG 900 is a potent and highly selective pan-Aurora kinases inhibitor for Aurora A/B/C with IC50 of 5 nM/4 nM /1 nM.Formule :C28H21N7OSDegré de pureté :98.4% - 99.51%Couleur et forme :SolidMasse moléculaire :503.58Ref: TM-T6380
1mg49,00€5mg92,00€10mg158,00€25mg286,00€50mg442,00€100mg645,00€500mg1.341,00€1mL*10mM (DMSO)100,00€3-Methoxybenzamide
CAS :3-Methoxybenzamide (3-MBA) is a competitive inhibitor of poly(ADP-ribose) synthetase.Formule :C8H9NO2Degré de pureté :98.52%Couleur et forme :SolidMasse moléculaire :151.16Amifostine trihydrate
CAS :Amifostine trihydrate (WR2721) is the first approved radioprotective drug, used to decrease the risk of kidney problems caused by treatment with cisplatin.Formule :C5H15N2O3PS·3H2ODegré de pureté :99.71% - 99.80%Couleur et forme :SolidMasse moléculaire :268.27Fosifidancitinib
CAS :Fosifidancitinib is a potent inhibitor of JAK 1 and JAK 3.Formule :C21H21FN5O7PDegré de pureté :99.54%Couleur et forme :SolidMasse moléculaire :505.39Ref: TM-T38624
1mg93,00€2mg117,00€5mg177,00€10mg269,00€25mg429,00€50mg610,00€100mg820,00€200mg1.099,00€ARV-771
CAS :ARV-771 is an effective BET degrader based on PROTAC technology.Cost-effective and quality-assured.Formule :C49H60ClN9O7S2Degré de pureté :99.69%Couleur et forme :SolidMasse moléculaire :986.64Ref: TM-T5435
1mg57,00€5mg113,00€10mg177,00€25mg354,00€50mg522,00€100mg732,00€200mg973,00€1mL*10mM (DMSO)192,00€Oclacitinib maleate
CAS :Oclacitinib maleate is a selective JAK inhibitor (IC50: 10-99 nM; JAK1 cytokines: 36-249 nM), with no effect on 38 non-JAK kinases.Formule :C15H23N5O2S·C4H4O4Degré de pureté :99.17% - 99.92%Couleur et forme :SolidMasse moléculaire :453.51Ref: TM-T6914
1mg37,00€2mg52,00€5mg74,00€10mg94,00€25mg166,00€50mg258,00€100mg432,00€1mL*10mM (DMSO)81,00€CPI-169 racemate
CAS :CPI-169 racemate (CPI 169) is a potent, and selective EZH2 inhibitor with IC50 of 0.24 nM, 0.51 nM, and 6.1 nM for EZH2 WT, EZH2 Y641N, and EZH1, respectively.
Formule :C27H36N4O5SDegré de pureté :99.59%Couleur et forme :SolidMasse moléculaire :528.66BET bromodomain inhibitor
CAS :BET bromodomain inhibitor is a potent BET inhibitor.Formule :C24H20ClN5O2Degré de pureté :98.22% - 99.85%Couleur et forme :SolidMasse moléculaire :445.9Ref: TM-T2072
1mg35,00€2mg50,00€5mg75,00€10mg114,00€25mg187,00€50mg264,00€100mg416,00€1mL*10mM (DMSO)84,00€ENMD-2076
CAS :ENMD-2076, a multi-targeted kinase inhibitor, has specific activity against Aurora A, Flt3, KDR/VEGFR2, Flt4/VEGFR3, FGFR1, FGFR2, Src, PDGFRα.Formule :C21H25N7Degré de pureté :97.63% - ≥95%Couleur et forme :SolidMasse moléculaire :375.47(Z)-SMI-4a
CAS :(Z)-SMI-4a (TCS PIM-1 4a) is a selective ATP-competitive Pim-1 kinase inhibitor with an IC50 of 21 nM.Formule :C11H6F3NO2SDegré de pureté :97.66% - 99.93%Couleur et forme :SolidMasse moléculaire :273.23Oclacitinib
CAS :Oclacitinib (PF-03394197)(PF03394197) is a potent and selective JAKs inhibitor with IC50 of 10-99 nM; not inhibit a panel of 38 non-JAK kinases (IC50 's > 1000Formule :C15H23N5O2SDegré de pureté :98% - 98.45%Couleur et forme :White To Off-White SolidMasse moléculaire :337.44lutidinic acid
CAS :lutidinic acid (2,4-Dicarboxypyridine) is an in vitro and in cell inhibitor, as well as a known inhibitor of the histone lysine demethylases.
Formule :C7H5NO4Degré de pureté :98.06%Couleur et forme :White To Off-White Crystalline PowderMasse moléculaire :167.12RG108
CAS :RG108 (N-Phthalyl-L-tryptophan) is an DNA methyltransferase inhibitor(IC50=115 nM).Formule :C19H14N2O4Degré de pureté :98% - 99.43%Couleur et forme :SolidMasse moléculaire :334.33Ref: TM-T2038
5mg44,00€10mg65,00€25mg111,00€50mg195,00€100mg271,00€200mg380,00€500mg618,00€1mL*10mM (DMSO)52,00€SGC-CBP30
CAS :SGC-CBP30 is an effective CREBBP/EP300 inhibitor (IC50: 21/38 nM).Formule :C28H33ClN4O3Degré de pureté :99.05% - >99.99%Couleur et forme :SolidMasse moléculaire :509.04Ref: TM-T6668
1mg50,00€2mg67,00€5mg84,00€10mg113,00€25mg200,00€50mg334,00€100mg500,00€1mL*10mM (DMSO)94,00€AZD-1480
CAS :AZD1480: JAK2 inhibitor, IC50 0.26 nM; selective vs Tyk2, JAK3; less on JAK1. Used in solid tumors, PPV, PMF, ET trials.Formule :C14H14ClFN8Degré de pureté :98.25% - 99.47%Couleur et forme :SolidMasse moléculaire :348.77JAK-IN-5 hydrochloride
CAS :JAK-IN-5 hydrochloride is a JAK inhibitor [1].Formule :C27H32ClFN6OCouleur et forme :SolidMasse moléculaire :511.03Barasertib-HQPA
CAS :Barasertib-HQPA (AZD2811) is a highly selective Aurora B inhibitor (IC50: 0.37 nM) and demonstrates ~3,700-fold greater selectivity than Aurora A.
Formule :C26H30FN7O3Degré de pureté :98.43% - 99.29%Couleur et forme :SolidMasse moléculaire :507.56ARV-825
CAS :ARV-825: PROTAC recruits BRD4 to cereblon for rapid BRD4 degradation in all tested BL cells.Formule :C46H47ClN8O9SDegré de pureté :97.15% - 98%Couleur et forme :SolidMasse moléculaire :923.43UNC6934
CAS :UNC6934 is a chemical probe targeting the N-terminal PWWP (PWWP1) domain of NSD2.Formule :C24H21N5O4Degré de pureté :98.67%Couleur et forme :SolidMasse moléculaire :443.45Ref: TM-T9584
1mg47,00€5mg92,00€10mg152,00€25mg326,00€50mg485,00€100mg670,00€200mg888,00€1mL*10mM (DMSO)101,00€Annaosanchun
CAS :Annaosanchun (YC-6) is potentially for the treatment of acute ischemic stroke (AIS).Formule :C19H32O3Degré de pureté :99.58%Couleur et forme :SolidMasse moléculaire :308.46Ruboxistaurin hydrochloride
CAS :Ruboxistaurin HCl (LY 333531) selectively inhibits PKCβI/II with IC50 of 4.7/5.9 nM; much less effective on other PKC types and ATP-kinases.Formule :C28H28N4O3·HClDegré de pureté :99.14% - 99.28%Couleur et forme :SolidMasse moléculaire :505.01Ref: TM-T3689
1mg67,00€2mg87,00€5mg148,00€10mg244,00€25mg487,00€50mg702,00€100mg982,00€500mg1.963,00€1mL*10mM (DMSO)190,00€TNG-462
CAS :TNG-462 is a oral, potent and selective PRMT5 inhibitor for the treatment of MTAP-deficient and/or MTA-accumulating cancers (e.g., pancreatic & bladder).Formule :C28H36N6O2SDegré de pureté :98.7%Couleur et forme :SolidMasse moléculaire :520.69Ref: TM-T79873
1mg147,00€5mg255,00€10mg383,00€25mg575,00€50mg863,00€100mg1.305,00€200mg1.755,00€1mL*10mM (DMSO)294,00€Osunprotafib
CAS :Osunprotafib (ABBV-CLS-484) is a potent, orally bioavailable PTP1B/PTPN2 inhibitor in clinical trials for solid tumors.Cost-effective and quality-assured.Formule :C17H24FN3O4SDegré de pureté :97.11% - 99.91%Couleur et forme :SolidMasse moléculaire :385.45MDL-800
CAS :MDL-800 is a SIRT6 modulator with antitumor activity for the study of hepatocellular carcinoma and non-small cell lung cancer.Formule :C21H16BrCl2FN2O6S2Degré de pureté :99.95% - 99.96%Couleur et forme :SolidMasse moléculaire :626.3(S)-HH2853
CAS :(S)-HH2853 is a potent EZH1/2 inhibitor, aromatic, <100 nM IC50 for EZH2_Y641F, promising for anti-tumor/autoimmune research.Formule :C31H36F3N7O3Degré de pureté :97.18% - 99.74%Couleur et forme :SolidMasse moléculaire :611.66CBHcy
CAS :CBHcy, a dual substrate analog, is a specific BHMT inhibitor that may induce cysteinemia.Formule :C9H17NO4SDegré de pureté :>99.99% - >99.99%Couleur et forme :SolidMasse moléculaire :235.3Chromium(III) acetate
CAS :Chromium(III) acetate （Chromium acetate） is a small molecule ionic crosslinker that is used as a feedstock for the synthesis of other compounds.Formule :C2H3O2CrDegré de pureté :99.9%Couleur et forme :Blue-Green Powder Environment Immediate Steps Should Be Taken To Limit Its Spread To The Environment It Is Used InMasse moléculaire :76.37MRK-740
CAS :MRK-740 is a PRDM9 histone methyltransferase inhibitor that inhibits H3K4 methylation.Formule :C25H32N6O3Degré de pureté :99.66%Couleur et forme :SolidMasse moléculaire :464.56Talazoparib tosylate
CAS :PF-3882845 is an MR antagonist that binds to the progesterone receptor (PR) and is used in the study of endocrine disorders and urogenital disorders.Formule :C26H22F2N6O4SDegré de pureté :99.79%Couleur et forme :SolidMasse moléculaire :552.55Ref: TM-T16979
2mg39,00€5mg58,00€10mg84,00€25mg128,00€50mg178,00€100mg295,00€200mg409,00€1mL*10mM (DMSO)71,00€CX-6258 hydrochloride
CAS :CX-6258 hydrochloride (Pim-Kinase Inhibitor X) is an effective, orally efficacious Pim1/2/3 kinase inhibitor (IC50: 5/25/16 nM).Formule :C26H24ClN3O3·HClDegré de pureté :96.03% - 98.60%Couleur et forme :SolidMasse moléculaire :498.4Ref: TM-T6148
1mg40,00€5mg84,00€10mg120,00€25mg222,00€50mg356,00€100mg537,00€200mg762,00€1mL*10mM (DMSO)93,00€BI-9321 trihydrochloride
CAS :BI-9321 trihydrochloride (BI9321 trihydrochloride) is an NSD3-PWWP1 antagonist that downregulates Myc messenger RNA expression.Formule :C22H24Cl3FN4Degré de pureté :99.12% - 99.34%Couleur et forme :SolidMasse moléculaire :469.81Zavondemstat
CAS :Zavondemstat (QC8222 free base) is a KDM4 inhibitor with anticancer and antitumor activity for the study of triple-negative and breast cancers.Formule :C26H29N3O3Degré de pureté :99.43% - 99.53%Couleur et forme :SolidMasse moléculaire :431.53CHDI-390576
CAS :CHDI-390576 is an HDAC inhibitor that inhibits class IIa HDAC 4, HDAC 5, HDAC 7, and HDAC 9, and can be used in cancer research.Formule :C19H13F4N3O2Degré de pureté :98.92% - 99.03%Couleur et forme :SolidMasse moléculaire :391.32MIV-6R
CAS :MIV-6R inhibits Menin-MLL interaction (IC50: 56 nM) and can be used to study leukemia.Formule :C27H35N3ODegré de pureté :99.81% - 99.88%Couleur et forme :SolidMasse moléculaire :417.59RGFP966 (E-isomer)
CAS :RGFP966 is an HDAC3 inhibitor with IC50 of 0.08 μM, exhibits > 200-fold selectivity over other HDAC.Formule :C21H19FN4ODegré de pureté :99.93%Couleur et forme :SolidMasse moléculaire :362.4MS023 dihydrochloride
CAS :MS023 dihydrochloride (MS023 2HCl) is a human type I protein arginine methyltransferase inhibitor with antitumour activity for the study of breast cancer.Formule :C17H27Cl2N3ODegré de pureté :99.52%Couleur et forme :SolidMasse moléculaire :360.32Cerdulatinib hydrochloride
CAS :Cerdulatinib hydrochloride is an oral tyrosine kinase inhibitor targeting JAK1/2/3, TYK2, Syk, and 19 others with IC50 < 200 nM.Formule :C20H28ClN7O3SDegré de pureté :99.85%Couleur et forme :SolidMasse moléculaire :482R 59-022
CAS :R 59-022 (DKGI-I) is a DGK inhibitor and a 5-HT Receptor antagonist that blocks filovirus internalization in host cells.Formule :C27H26FN3OSDegré de pureté :98.55%Couleur et forme :SolidMasse moléculaire :459.58Ref: TM-T16709
1mg35,00€5mg74,00€10mg119,00€25mg269,00€50mg447,00€100mg733,00€200mg973,00€1mL*10mM (DMSO)75,00€PFI-2
CAS :PFI-2 is an effective, specific and cell-active lysine methyltransferase SETD7 inhibitor (Ki/IC50: 0.33/2 nM), 1000-fold selectivity over otherFormule :C23H25F4N3O3SDegré de pureté :99.38%Couleur et forme :SolidMasse moléculaire :499.52MK-5108
CAS :MK-5108 (VX-689) is a highly potent and specific Aurora-A kinase inhibitor with an IC50 value of 0.064 nM.Formule :C22H21ClFN3O3SDegré de pureté :99.22%Couleur et forme :SolidMasse moléculaire :461.94Dehydrocorydaline nitrate
CAS :DHC curbs antibody and cell-mediated allergies, inhibits mitochondrial potential in macrophages, and has antinociceptive, anti-inflammatory effects.Formule :C22H24N2O7Degré de pureté :99.79% - 99.92%Couleur et forme :SolidMasse moléculaire :428.44Ref: TM-T2S2362
1mg89,00€5mg205,00€10mg334,00€25mg552,00€50mg782,00€100mg1.054,00€200mg1.414,00€1mL*10mM (DMSO)243,00€PF-03814735
CAS :PF-03814735 is a novel, potent and reversible inhibitor of Aurora A/B with IC50of 0.8 nM/5 nM, is less potent to Flt3, FAK, TrkA, and minimally active to Met and FGFR1. Phase 1.Formule :C23H25F3N6O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :474.48SCH-1473759 hydrochloride
CAS :SCH-1473759 hydrochloride is an inhibitor of aurora(aurora A and B with IC50s of 4 and 13 nM, respectively).Formule :C20H27ClN8OSDegré de pureté :98.29%Couleur et forme :SolidMasse moléculaire :463GSK2807 Trifluoroacetate
CAS :GSK2807 Trifluoroacetate is a selective and SAM-competitive inhibitor of SMYD3 (Ki: 14 nM; IC50: 130 nM).Formule :C21H33F3N8O7Degré de pureté :99.95%Couleur et forme :SolidMasse moléculaire :566.53NVP-BSK805
CAS :NVP-BSK805 (BSK 805) is an ATP-competitive JAK2 inhibitor.Formule :C27H28F2N6ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :490.55Acedapsone
CAS :Acedapsone has antimalarial and antimicrobial action, but is mainly used as a depot leprostatic agent.Formule :C16H16N2O4SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :332.37Tazemetostat trihydrochloride
CAS :Tazemetostat trihydrochloride, an EZH2 inhibitor, orally active, IC50: 4nM (rat), Ki: 2.5nM (human), effective in peptide and nucleosome assays.Formule :C34H47Cl3N4O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :682.12(R)-Dihydrolipoic acid
CAS :(R)-Dihydrolipoic acid, the biochemically significant R-enantiomer, partakes in biochemical transformations.Formule :C8H16O2S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :208.33TETi76
CAS :TETi76 is an orally active inhibitor from the TET family, demonstrating IC50 values of 1.5, 9.4, and 8.8 μM against TET1, TET2, and TET3, respectively. The compound competitively binds to the active sites of TET enzymes, reducing cytosine hydroxymethylation and restricting clonal growth in mutated TET2 in vitro and in vivo, without affecting the growth of normal hematopoietic progenitor cells. TETi76 is utilized in leukemia research.Formule :C10H16O5Couleur et forme :SolidMasse moléculaire :216.232-PADQZ
CAS :DPQ is an antiviral compound.Formule :C14H19N5O2Degré de pureté :98%Couleur et forme :White PowderMasse moléculaire :289.33Diethyl bipy55'DC
CAS :"Diethyl bipy55'DC blocks CP4H, crucial for collagen stability via hydroxylation in cells."Formule :C16H16N2O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :300.31GSK 4027
CAS :GSK 4027 is a PCAF/GCN5 bromodomain chemical probe. In a time-resolved fluorescence resonance energy transfer (TR-FRET) assay, it has a pIC50 of 7.4±0.11 for PCAF.Formule :C17H21BrN4OCouleur et forme :SolidMasse moléculaire :377.28Nicotinamide-d4
CAS :Nicotinamide-d4 is a deuterium-labelled compound of nicotinamide for isotope tracing. Nicotinamide, a vitamin B3 derivative, inhibits SIRT1 and SIRT2.Formule :C6H2D4N2ODegré de pureté :99.746%Couleur et forme :SolidMasse moléculaire :126.15193 D7
CAS :193 D7 is an inhibitor of histone demethylase JMJD1C (IC50= 0.59 μM in in vitro demethylation assay). In vivo, 193 D7 suppresses tumors by targeting intratumoral Treg cells in mouse tumor models.Formule :C16H15NO4SCouleur et forme :SolidMasse moléculaire :317.36BRD 4354 ditrifluoroacetate
BRD 4354 (ditrifluoroacetate) is a moderately potent inhibitor of HDAC5 and HDAC9 (IC50s: 0.85 and 1.88 μM).Formule :C25H25ClF6N4O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :610.93KR-39038
CAS :KR-39038 is an oral GRK5 inhibitor for heart failure research; blocks HDAC5 pathway, IC50: 0.02 μM, fights cardiac hypertrophy.Formule :C24H32ClFN6OCouleur et forme :SolidMasse moléculaire :475.00CrBKA
CAS :CrBKA is a fluorogenic small-molecule substrate of SIRT6 with weak activity [1] .Formule :C28H31N3O6Couleur et forme :SolidMasse moléculaire :505.56BChE/HDAC6-IN-2
CAS :BChE/HDAC6-IN-2 is an inhibitor of BChE and HDAC6 with neuroprotective and ROS scavenging activity and a metal ion co-agonist and inhibits tau phosphorylation.Formule :C27H30N4O4Degré de pureté :98.47%Couleur et forme :SoildMasse moléculaire :474.55AdipoR agonist 1
CAS :AdipoR agonist 1 (Compound 112254), acting as an agonist for the adiponectin receptor (AdipoR), stimulates transcriptional regulators including peroxisome proliferator-activated receptors (PPARs), peroxisome proliferator-activated receptor gamma coactivator 1α (PGC-1α), sirtuin 1 (SIRT1), and adenylate-activated protein kinase (AMPK). It is employed in the field of preventive doping research.Formule :C26H35N3O3Couleur et forme :SolidMasse moléculaire :437.57BG14
CAS :BG14: High-res optical epigenetic control; photo-inhibits human histone deacetylases with visible light.Formule :C21H21N5OCouleur et forme :SolidMasse moléculaire :359.433I-BET787
CAS :I-BET787, an orally active pan-BET bromodomain inhibitor, has demonstrated efficacy in murine inflammation models.Formule :C16H20ClN3O2Couleur et forme :SolidMasse moléculaire :321.80HDAC2-IN-2
CAS :HDAC2-IN-2 (compound 124) acts as an HDAC2 inhibitor, exhibiting a Kd value ranging from 0.1-1 μM.Formule :C18H15N3O3SCouleur et forme :SolidMasse moléculaire :353.40BG47
CAS :BG47: a COMET probe for precise optical epigenetic control, inhibits histone deacetylases with light.Formule :C25H22N4O2SCouleur et forme :SolidMasse moléculaire :442.54GSK-J1 lithium salt
CAS :GSK-J1 lithium salt is an effective inhibitor of H3K27me3/me2-demethylases JMJD3/KDM6B and UTX/KDM6A, with an IC 50 of 60 nM for KDM6B.Formule :C22H22LiN5O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :395.38Guanosine-5'-triphosphate disodium salt
CAS :5'-GTP disodium salt boosts myogenic differentiation and fuels cellular processes.Formule :C10H14N5Na2O14P3Degré de pureté :95.69% - 99.96%Couleur et forme :Odorless White SolidMasse moléculaire :567.14BG48
CAS :BG48, a COMET probe, enables precise optical epigenetic control and photochromically blocks human histone deacetylases with visible light.Formule :C25H23N5OSCouleur et forme :SolidMasse moléculaire :441.55KAT6-IN-1
CAS :KAT6-IN-1 (compound E) is a selective, orally available inhibitor of histone acetyltransferases KAT6A and KAT6B, exhibiting antitumour activity for cancer.Formule :C19H18N4O5SDegré de pureté :99.86%Couleur et forme :SolidMasse moléculaire :414.43Asteltoxin
CAS :Asteltoxin is a useful organic compound for research related to life sciences. The catalog number is T124203 and the CAS number is 79663-49-3.Formule :C23H30O7Couleur et forme :SolidMasse moléculaire :418.486PKCTheta-IN-2
CAS :PKCTheta-IN-2 (compound 14) is a potent and selective PKCθ inhibitor (IC50 = 0.25 nM) that suppresses IL-2 production in mice (IC50 = 682 nM).Formule :C24H23N5O2Degré de pureté :99.38%Couleur et forme :SolidMasse moléculaire :413.47HDAC6-IN-27
CAS :HDAC6-IN-27 (compound 8C), an HDAC inhibitor, exhibits IC 50 values of 15.9 nM, 136.5 nM, and 6180.2 nM against HDAC6, HDAC8, and HDAC1, respectively. It also demonstrates potent antiparasitic effects [1].Formule :C15H15N3O4Couleur et forme :SolidMasse moléculaire :301.3(3S,4S)-Tofacitinib
CAS :(3S,4S)-Tofacitinib, a less active enantiomer of tofacitinib, is a Janus kinases inhibitor.Formule :C16H20N6ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :312.37E3330
CAS :E3330 is a potent and selective APE1(Ref-1) inhibitor, which suppressed NF-kappa B DNA-binding activity.Formule :C21H30O6Degré de pureté :99.52%Couleur et forme :SolidMasse moléculaire :378.46Phorbol 12,13-dibutyrate
CAS :Phorbol 12,13-dibutyrate (Phorbol dibutyrate) is a PKC activator that induces contraction of isolated rabbit vascular smooth muscle.Formule :C28H40O8Degré de pureté :99.32% - 99.37%Couleur et forme :SolidMasse moléculaire :504.61Ref: TM-T16526
1mg58,00€5mg160,00€10mg268,00€25mg530,00€50mg827,00€100mg1.314,00€200mg1.773,00€1mL*10mM (DMSO)170,00€
