Chromatine/Épigénétique
Les inhibiteurs de la chromatine/épigénétique sont des composés qui modulent la structure et la fonction de la chromatine ou interfèrent avec les modifications épigénétiques, telles que la méthylation de l'ADN et la modification des histones. Ces inhibiteurs sont des outils essentiels pour étudier la régulation de l'expression génique et le rôle de l'épigénétique dans des maladies telles que le cancer, les troubles neurologiques et les anomalies du développement. En ciblant les processus épigénétiques, ces inhibiteurs peuvent modifier les schémas d'expression génique et offrir de nouvelles perspectives thérapeutiques. Chez CymitQuimica, nous offrons une large sélection d'inhibiteurs de la chromatine/épigénétique de haute qualité pour soutenir vos recherches en biologie moléculaire, génétique et épigénétique.
Sous-catégories appartenant à la catégorie "Chromatine/Épigénétique"
2235 produits trouvés pour "Chromatine/Épigénétique"
Trier par
Degré de pureté (%)
0
100
|
0
|
50
|
90
|
95
|
100
AZD-1897
CAS :<p>AZD-1897 is a highly efficient ATP-competitive pan-PIM inhibitor with anti-cancer and anti-leukemia activity, used in multiple myeloma research.</p>Formule :C18H23N3O3SDegré de pureté :99.49%Couleur et forme :SolidMasse moléculaire :361.46PNZ5
CAS :<p>PNZ5, an isoxazole-based pan-BET inhibitor, demonstrates potent activity and high selectivity comparable to the established (+)-JQ1, exhibiting a dissociation</p>Formule :C20H18N2O2Degré de pureté :99.51% - 99.61%Couleur et forme :SolidMasse moléculaire :318.37KBH-A42
CAS :<p>KBH-A42 is an inhibitor of histone deacetylase.</p>Formule :C17H22N2O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :302.37JAK3/BTK-IN-1
CAS :<p>JAK3/ BTk-in-1 is a dual JAK3/BTK inhibitor that specifically targets and inhibits Janus kinase 3 (JAK3) and Bruton's tyrosine kinase (BTK), two important</p>Formule :C25H28N8ODegré de pureté :97.89%Couleur et forme :SolidMasse moléculaire :456.54DS-437
CAS :<p>DS-437 is a dual PRMT5/7 inhibitor (IC50s: 6 μM). DS-437 also inhibits DNMT3A and DNMT3B (IC50s: 52 and 62 μM). DS-437 inhibits the methylation of FOXP3.</p>Formule :C15H23N7O4SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :397.45JAK-IN-10
CAS :<p>JAK-IN-10 is a JAK inhibitor. JAK-IN-10 can be used for the research of dry eye disorders.</p>Formule :C20H18FN5O3SDegré de pureté :99.53%Couleur et forme :SolidMasse moléculaire :427.45(2R/S)-6-PNG
CAS :<p>(2R/S)-6-PNG (6-Prenylnaringenin) from hops is a natural histone deacetylase inhibitor that blocks T-type calcium channels reducing neurogenicity in mice.</p>Formule :C20H20O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :340.37SW155246
CAS :<p>SW155246 is a potent and selective inhibitor of DNMT1 (DNA methyltransferase 1; IC50 of 1.2 μM).</p>Formule :C16H11ClN2O5SDegré de pureté :98.99%Couleur et forme :SolidMasse moléculaire :378.79SIRT5 inhibitor 5
CAS :<p>SIRT5 inhibitor 5 is a selective and substrate-competitive SIRT5 inhibitor, which does not occupy the NAD+ binding pocket,cancer and metabolism-related disease.</p>Formule :C21H14ClN3O3SDegré de pureté :99.33%Couleur et forme :SolidMasse moléculaire :423.87EPZ032597
CAS :<p>EPZ032597 is a novel selective inhibitor of SMYD2 with an IC50 of 16 nM. EPZ032597 has anticancer activity and prevent and treat pancreatic cancer</p>Formule :C20H23N7ODegré de pureté :99.70%Couleur et forme :SolidMasse moléculaire :377.44KP-302
CAS :<p>KP-302 is a selective PAD inhibitor, reversing physical disability in multiple sclerosis (MS) mice and clearing T-cell infiltration in the brain.</p>Formule :C20H23N5O2Degré de pureté :99.77%Couleur et forme :SolidMasse moléculaire :365.43JAK-IN-28
CAS :<p>JAK-IN-28 (Compound 111) is a Janus kinase (JAK) inhibitor potentially applicable in the research of cancer and inflammatory diseases [1].</p>Formule :C20H18ClN7ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :407.86Valemetostat tosylate
CAS :<p>Valemetostat tosylate is a dual inhibitor of EZH1/2 and used in the research of relapsed/refractory peripheral T-cell lymphoma.</p>Formule :C33H42ClN3O7SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :660.22BET-IN-7
CAS :<p>BET-IN-7 is a potent BET inhibitor with a Ki of 12.27 μM and Kd of 89.3 μM, useful in sepsis research.</p>Formule :C18H12ClN3OSCouleur et forme :SolidMasse moléculaire :353.83Furamidine
CAS :<p>Furamidine is a PRMT1-selective, cell-permeable inhibitor (IC50: 9.4μM), also targeting TDP-1, and is an antiparasitic bisbenzamidine derivative.</p>Formule :C18H16N4ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :304.35GSK360A
CAS :<p>GSK360A is a novel prolyl hydroxylase (PHD) domain-containing enzyme inhibitor.</p>Formule :C17H17FN2O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :348.33Ilorasertib hydrochloride
CAS :<p>Ilorasertib hydrochloride (ABT-348 hydrochloride) is an ATP-competitive multitargeted kinase inhibitor, which inhibits Aurora C, Aurora B, and Aurora A (IC50s:</p>Formule :C25H22ClFN6O2SDegré de pureté :98.45%Couleur et forme :SolidMasse moléculaire :525JAK-IN-14
CAS :<p>JAK-IN-14 (compound 16) is a specific JAK1 inhibitor. It prevents JAK1 phosphorylation by binding to the active site of JAK in immune, inflammation and cancer.</p>Formule :C19H15FN4ODegré de pureté :98.27%Couleur et forme :SolidMasse moléculaire :334.35Aurora kinase inhibitor-10
CAS :<p>Aurora kinase inhibitor-10 is an orally active Aurora B inhibitor (IC50: 8 nM) that exhibits antitumour effects.</p>Formule :C21H19F5N6O4SCouleur et forme :SolidMasse moléculaire :546.47MT477
CAS :<p>MT477 inhibits PKC-α, impairs Ras/ERK1/2 phosphorylation, induces apoptosis, and reduces proliferation in various cancer cells.</p>Formule :C31H30N2O12S3Couleur et forme :SolidMasse moléculaire :718.77Rucaparib camsylate
CAS :<p>Rucaparib camsylate, a PARP-1, -2, -3 inhibitor (Ki=1.4 nM for PARP-1) & H6PD blocker, may treat resistant prostate cancer.</p>Formule :C19H18FN3O·xC10H16O4SCouleur et forme :SolidHIF-PHD-IN-2
CAS :<p>HIF-PHD-IN-2 (compound 25) is a highly effective PHD inhibitor, displaying IC50 values below 100 nM for PHD1, PHD2, and PHD3 [1].</p>Formule :C17H15N5O3SCouleur et forme :SolidMasse moléculaire :369.4dWIZ-1
CAS :<p>dWIZ-1 ((rac)-dWIZ-1) is a potent WIZ molecular gel degrader tha induction of haemoglobin fetalis (HbF) in erythroblasts, sickle cell disease (SCD).</p>Formule :C22H29N3O4Degré de pureté :92.87% - 92.87%Couleur et forme :SolidMasse moléculaire :399.48Y08284
CAS :<p>Y08284: selective CBP bromodomain inhibitor, IC50: 4.21 nM, oral. Halts prostate cancer cell growth; anti-tumor.</p>Formule :C26H25FN4O4Couleur et forme :SolidMasse moléculaire :476.5HIF-1/2α-IN-2
CAS :<p>HIF-1/2α-IN-2 is a potent inhibitor of HIF-1/2α, which effectively reduces the levels of HIF-1/2α.</p>Formule :C16H11FN4O2SCouleur et forme :SolidMasse moléculaire :342.35Tetrahydrouridine
CAS :<p>Tetrahydrouridine (NSC-112907; THU) is a multidrug resistance modulator.</p>Formule :C9H16N2O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :248.23Bizine
CAS :<p>Bizine, a Phenelzine analogue, selectively inhibits LSD1 (Ki=59 nM), modulates histone methylation in cancer, and may have neuroprotective uses.</p>Formule :C18H23N3OCouleur et forme :SolidMasse moléculaire :297.39Thi-DPPY
CAS :<p>Thi-DPPY: Potent JAK3/BTK inhibitor (IC50: 1.38/62.4 nM), anti-proliferative, anti-inflammatory, potential in IPF research.</p>Formule :C28H28ClN5O4SCouleur et forme :SolidMasse moléculaire :566.07HDAC3-IN-T247
CAS :<p>HDAC3-IN-T247 (HDAC3 inhibitor T247) is a histone deacetylase 3 (HDAC3) inhibitor with antiviral activity that inhibits the proliferation of cancer cells.</p>Formule :C21H19N5OSDegré de pureté :98.11% - 98.94%Couleur et forme :SolidMasse moléculaire :389.47SIRT1-IN-2
CAS :<p>SIRT1-IN-2 (compound 3h) is a potent and selective inhibitor of SIRT1 (silent information regulator 1) with an IC 50 of 1.6 μM [1].</p>Formule :C13H15ClN2OCouleur et forme :SolidMasse moléculaire :250.72IDO1 and HDAC1 Inhibitor
CAS :<p>IDO1 and HDAC1 Inhibitor is a dual IDO1 and HDAC1 inhibitor (IC50s: 69.0 nM and 66.5 nM).</p>Formule :C25H22BrFN8O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :597.4HDAC-IN-49
<p>HDAC-IN-49: potent, broad HDAC inhibitor; IC50s: 10-1880 nM for HDAC1-6; strong anti-leukemic, low toxicity to healthy cells.</p>Formule :C26H27FN4O4Couleur et forme :SolidMasse moléculaire :478.52CYP51/HDAC-IN-1
CAS :<p>Orally active CYP51/HDAC-IN-1 dual inhibitor targets virulence factors and resistance genes; effective against Candidiasis and Cryptococcal meningitis.</p>Formule :C30H40F2N6O4Couleur et forme :SolidMasse moléculaire :586.67TFMB-(S)-2-HG
CAS :<p>TFMB-(S)-2-HG (TFMB S 2 HG) is a highly effective inhibitor of TET2, the 5'-methylcytosine hydroxylase.</p>Formule :C13H11F3O4Degré de pureté :98.07%Couleur et forme :SolidMasse moléculaire :288.22Sirt1/2-IN-1
CAS :<p>Sirt1/2-IN-1 inhibits SIRT1 (IC50: 1.81 μg/mL) and SIRT2 (2.10 μg/mL), less on SIRT3 (20.5 μg/mL), with anticancer properties.</p>Formule :C22H13ClN2OS2Couleur et forme :SolidMasse moléculaire :420.93HDAC6-IN-15
<p>HDAC6-IN-15: selective HDAC6 inhibitor, IC50 of 38.2 nM, for cancer and neurodegenerative research.</p>Formule :C25H28FFeN3O2Couleur et forme :SolidMasse moléculaire :477.35M133
CAS :<p>M133 is a selective histone deacetylase HDAC1 and HDAC2 inhibitor and potent antitumor agent.</p>Formule :C23H24N4OS2Couleur et forme :SolidMasse moléculaire :436.59CBHA
CAS :<p>m-Carboxycinnamic bishydroxamide: HDAC inhibitor, ID50 = 10 nM (HDAC1), 70 nM (HDAC3), induces apoptosis and tumor growth suppression.</p>Formule :C10H10N2O4Couleur et forme :SolidMasse moléculaire :222.2Peficitinib hydrobromide
CAS :<p>Peficitinib hydrobromide is used in the treatment of Psoriasis and Rheumatoid Arthritis.</p>Formule :C18H23BrN4O2Couleur et forme :SolidMasse moléculaire :407.312PIM-1 Inhibitor 2
CAS :<p>PIM-1 Inhibitor 2 (PIM1-IN-2) is a potent Pim-1 inhibitor with potential anti-cancer activity, used in cancer research.</p>Formule :C17H11ClN4ODegré de pureté :98.81%Couleur et forme :SolidMasse moléculaire :322.75MI-2-2
CAS :<p>MI-2-2 is an inhibitor of bivalent protein-protein interaction between menin and MLL with an IC50 of 46 nM. MI-2-2 binds to menin with Kd of 22 nM.</p>Formule :C17H20F3N5S2Degré de pureté :99.65%Couleur et forme :SolidMasse moléculaire :415.5OUL245
CAS :<p>OUL245: A selective PARP2 inhibitor (IC50=44nM), also inhibits other PARPs/TNKS (IC50=2.9-8.8μM).</p>Formule :C8H5N3OSCouleur et forme :SolidMasse moléculaire :191.21YM-53601
CAS :<p>YM-53601 is an SQS inhibitor that inhibits adipogenic biosynthesis and lipid secretion in rodents.YM-53601 is a cholesterol-lowering agent that inhibits FDFT1.</p>Formule :C21H22ClFN2ODegré de pureté :99.65%Couleur et forme :SolidMasse moléculaire :372.86IACS-9571
CAS :<p>IACS-9571 is a selective and potent inhibitor of TRIM24 and BRPF1, (IC50: 8 nM for TRIM24; Kds: 31 nM and 14 nM for TRIM24 and BRPF1).</p>Formule :C32H42N4O8SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :642.76Tyk2-IN-5
CAS :<p>Tyk2-IN-5 is a selective and orally active inhibitor of Tyk2 JH2 (Ki: 0.086 nM for Tyk2 JH2; IC50: 25 nM for IFNα).</p>Formule :C21H19FN8O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :434.43CPI703
CAS :<p>CPI703 is a novel potent and specific CBP/EP300 bromodomain inhibitor.</p>Formule :C17H22N4ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :298.38JAK3/BTK-IN-2
CAS :<p>JAK3/ BTk-in-2 is a potent JAK3/BTK inhibitor.</p>Formule :C25H32N8O2Degré de pureté :99.64% - 99.87%Couleur et forme :SolidMasse moléculaire :476.57Bromodomain IN-1
CAS :<p>Bromodomain IN-1 is an inhibitor of Bromodomain.</p>Formule :C22H23ClN4O3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :458.962′-Deoxy-5-nitrocytidine
CAS :<p>2′-Deoxy-5-nitrocytidine is a DNA Methyltransferase inhibitor that can be used for cancer research[1].</p>Formule :C9H12N4O6Couleur et forme :SolidMasse moléculaire :272.216-Methyl-5-azacytidine
CAS :<p>6-Methyl-5-azacytidine is a potent DNMT inhibitor.</p>Formule :C9H14N4O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :258.23SB-284851-BT
CAS :<p>SB-284851-BT: BRD4/p38α/BRDT inhibitor; IC50: BRD4-BD1 1.7µM, BRDT 18µM, BRD4 3.7µM; Kd p38α 0.47nM; reduces IL-8, affects c-Myc/NF-κB.</p>Formule :C26H26FN5OCouleur et forme :SolidMasse moléculaire :443.52BET-BAY 002 (S enantiomer)
CAS :<p>The S-enantiomer of BET-BAY 002, referred to as BET-BAY 002 S enantiomer, is a potent inhibitor of BET (Bromodomain and Extra-Terminal motif proteins).</p>Formule :C22H18ClN5ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :403.86PKC-IN-4
CAS :<p>PKC-IN-4 (compound 7l) is a highly potent and orally active inhibitor of atypical protein kinase C (aPKC), exhibiting an IC 50 value of 0.52 μM.</p>Formule :C21H25N5SCouleur et forme :SolidMasse moléculaire :379.52CD161
CAS :<p>CD161: powerful, selective oral BET inhibitor; IC50: 28.2 nM (BRD4 BD1), 7.2 nM (BRD4 BD2); strong anticancer properties.</p>Formule :C26H21N5O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :435.48YF479
CAS :<p>YF479 is an inhibitor of histone deacetylase that acts by inhibiting breast tumor growth, metastasis, and recurrence.</p>Formule :C22H27BrN2O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :479.36TC-E 5001
CAS :<p>dual tankyrase (TNKS) inhibitor</p>Formule :C20H19N5O3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :409.46DC-CPin7
CAS :<p>DC-CPin7, a powerful inhibitor of the bromodomain of CREB-binding protein (CBP), exhibits an IC50 value of 2.5 μM [1].</p>Formule :C19H22N2O5Couleur et forme :SolidMasse moléculaire :358.39OICR-0547
CAS :<p>OICR-0547 is an inactive derivative of OICR-9429 and is commonly used as a negative control for OICR-9429.</p>Formule :C28H29F3N4O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :542.55HIF-1α inhibitor-1
CAS :<p>HIF-1α inhibitor-1 is a HIF-1 alpha inhibitor.</p>Formule :C15H11N3O4Couleur et forme :SolidMasse moléculaire :297.27Cercosporamide
CAS :<p>Cercosporamide is a ATP-competitive Pkc1 kinase inhibitor (IC50 <50 nM; Ki <7 nM). It also is a unique Mnk inhibitor.</p>Formule :C16H13NO7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :331.28Bisindolylmaleimide II
CAS :<p>protein kinase C (PKC) inhibitor</p>Formule :C27H26N4O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :438.52LSD1-IN-12
CAS :<p>LSD1-IN-12 (compound 2) is an effective inhibitor of LSD1, demonstrating inhibitory Ki values of 1.1 μM (LSD1), 61 μM (LSD2), 2.3 μM (MAO-A), and 3.5 μM (MAO-B</p>Formule :C16H16N2OCouleur et forme :SolidMasse moléculaire :252.31OM-137
CAS :<p>OM137 inhibits Aurora kinases, impedes cell growth at high doses, and enhances low-dose paclitaxel effects.</p>Formule :C13H14N4O3SCouleur et forme :SolidMasse moléculaire :306.34SRTCX1002
CAS :<p>SRTCX1002 is a SIRT1 Activator Suppressing Inflammatory Responses through Promotion of p65 Deacetylation and NF-κB Activity inhibitor.</p>Formule :C21H19N5O2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :405.47AMPK activator 6
CAS :<p>AMPK activator 6 stimulates AMPK, lowers lipids in cells, and reduces serum TC, LDL-C, and TG. Useful for NAFLD and metabolic research.</p>Formule :C25H28O5Couleur et forme :SolidMasse moléculaire :408.49ZLD1039
CAS :<p>ZLD1039, an oral EZH2 inhibitor, shows strong PRC2 inhibition at low nanomolar IC50s, and halts breast cancer growth and spread.</p>Formule :C36H48N6O3Degré de pureté :99.5%Couleur et forme :SolidMasse moléculaire :612.8PU141
CAS :<p>PU141 is a novel inhibitor of histone acetyltransferase (HAT).</p>Formule :C14H9F3N2OSDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :310.29CHIC35
CAS :<p>CHIC-35 is a selective deacetylase SIRT1 inhibitor.</p>Formule :C14H15ClN2OCouleur et forme :SolidMasse moléculaire :262.73OTS186935 trihydrochloride
CAS :<p>OTS186935 trihydrochloride is a protein methyltransferase inhibitor of SUV39H2(IC50 of 6.49 nM).</p>Formule :C25H29Cl4N5O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :573.34GNA002
CAS :<p>GNA002 is a highly potent, specific, and covalent EZH2 (Enhancer of zeste homolog 2) inhibitor (IC50: 1.1 μM).</p>Formule :C42H55NO8Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :701.89ET-JQ1-OH
CAS :<p>ET-JQ1-OH is an allele-specific BET inhibitor.</p>Formule :C21H21ClN4O2SCouleur et forme :SolidMasse moléculaire :428.93SMTIN-T140
CAS :<p>SMTIN-T140: strong TRAP1 inhibitor, IC50=1.646μM, anticancer; disrupts mitochondria, boosts ROS, activates AMPK, shrinks PC3 tumors, no in vivo toxicity.</p>Formule :C36H34BrClFN5OPDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :718.02F5446
CAS :<p>F5446 is a selective small molecule SUV39H1 methyltransferase inhibitor, promotes apoptosis in colorectal cancer cells by inhibiting the deposition of H3K9me3.</p>Formule :C26H17ClN2O8SDegré de pureté :98.56%Couleur et forme :SolidMasse moléculaire :552.94MicroRNA-21-IN-2
CAS :<p>MicroRNA-21-IN-2 is a potential miR-21 inhibitor with an AC50 value of 3.29 μM. MicroRNA-21-IN-2 can be used to study cancer.</p>Formule :C17H15N3O3SDegré de pureté :99.2%Couleur et forme :SolidMasse moléculaire :341.38CX-6258
CAS :<p>CX-6258 is an orally valid Pim 1/2/3 kinase(IC50=5 nM/25 nM/16 nM) inhibitor. It has good biological activity and kinase specificity.</p>Formule :C26H24ClN3O3Degré de pureté :97.46%Couleur et forme :SolidMasse moléculaire :461.94BAY1238097
CAS :<p>BAY1238097 is a BET inhibitor with anticancer activity and antiproliferative activity for the study of advanced refractory malignancies.</p>Formule :C25H33N5O3Degré de pureté :98.1% - 98.79%Couleur et forme :SolidMasse moléculaire :451.56EZH2-IN-3
CAS :<p>EZH2-IN-3 is an inhibitor of EZH2 and EZH1 with selective impact on diffuse large B cell lymphoma cell growth.</p>Formule :C27H28ClN5O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :490CSV0C018875
CAS :<p>CSV0C018875 is a quinoline-based EHMT2/G9a inhibitor with lower cytotoxicity than BIX-01294 [1].</p>Formule :C18H17ClN2OCouleur et forme :SolidMasse moléculaire :312.79SPV106
CAS :<p>SPV106 is a ligand of lysine acetyltransferases (KATs).</p>Formule :C22H40O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :368.55BIX-01338 hydrate
CAS :<p>BIX-01338 hydrate is an inhibitor of histone lysine methyltransferase.</p>Formule :C32H26F3N3O7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :621.56(2R,5S)-Ritlecitinib
CAS :<p>(2R,5S)-Ritlecitinib ((2R,5S)-PF-06651600) is a potent and selective inhibitor of JAK3 with IC 50 of 144.8 nM[1].</p>Formule :C15H19N5OCouleur et forme :SolidMasse moléculaire :285.34PI3K/Akt/CREB activator 1
CAS :<p>PI3K/Akt/CREB activator 1 (AE-18) is an iNOS inhibitor that can be used to study vascular dementia and Parkinson's.</p>Formule :C19H15F4NO3Couleur et forme :SolidMasse moléculaire :381.32Povorcitinib
CAS :<p>Povorcitinib is a highly potent and selective JAK1 inhibitor with significant potential for the investigation of cutaneous lupus erythematosus (CLE) and Lichen planus (LP).</p>Formule :C23H22F5N7OCouleur et forme :SolidMasse moléculaire :507.469JAK3-IN-1
CAS :<p>JAK3-IN-1 is an orally active, selective and potent JAK3 inhibitor for the study of immune system disorders.</p>Formule :C26H30ClN7O2Couleur et forme :SolidMasse moléculaire :508.02SRTCX1003
CAS :<p>SRTCX1003, a SIRT1 activator, suppresses inflammatory responses through promotion of p65 deacetylation and inhibition of NF-κB activity.</p>Formule :C23H23N5O3SCouleur et forme :SolidMasse moléculaire :449.53Aurora Kinases-IN-3
CAS :<p>Aurora Kinases-IN-3 is an oral AURKB inhibitor that disrupts its mitotic localization, not its H3 Ser10 phosphorylation.</p>Formule :C20H16F3N3O4Couleur et forme :SolidMasse moléculaire :419.35PBRM1-BD2-IN-6
CAS :<p>PBRM1-BD2-IN-6: potent PBRM1 inhibitor with 0.22 µM IC50, anti-cancer research potential.</p>Formule :C16H15ClN2OCouleur et forme :SolidMasse moléculaire :286.76CK2/PIM1-IN-1
CAS :<p>CK2/PIM1-IN-1 inhibits CK2 & PIM1 (IC50s: 3.787 & 4.327 μM), aimed for cancer research.</p>Formule :C15H9NO4S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :331.37HDAC3 Inhibitor
CAS :<p>HDAC3 inhibitor: allosteric, Ki=0.16 nM, favors HDAC3 over HDAC1/2, targets specific leukemia cells, EC50=36.37-151.7 nM.</p>Formule :C20H23N3O2Couleur et forme :SolidMasse moléculaire :337.42AMPK activator 8
CAS :<p>AMPK activator 8 targets rAMPK α1β1γ1/α2β1γ1/α1β2γ1 (EC50: 11/27/4 nM) for type 2 diabetes research.</p>Formule :C25H21ClN2O6Couleur et forme :SolidMasse moléculaire :480.9RET-IN-19
CAS :<p>RET-IN-19, a potent RET inhibitor, anticancer: IC50 6.8 nM (RET-wt), 13.51 nM (RET V804M); for NSCLC research.</p>Formule :C28H28N6O4SCouleur et forme :SolidMasse moléculaire :544.62KCN1
CAS :<p>KCN1: a synthetic sulfonamide, nanomolar HIF inhibitor with preclinical anti-glioma and anti-pancreatic cancer effects.</p>Formule :C26H27NO5SCouleur et forme :SolidMasse moléculaire :465.56SIRT2-IN-10
CAS :<p>SIRT2-IN-10 (Compound 12) is a potent inhibitor of SIRT2 (IC50: 1.3 μM), which can be used in the study of cancer and neurodegenerative diseases.</p>Formule :C28H21N5OSCouleur et forme :SolidMasse moléculaire :475.56SIRT5 inhibitor 4
CAS :<p>SIRT5 inhibitor 4 (compound 11) is a dose-dependent and selective SIRT5 (Sirtuin5) inhibitorand no inhibitory effect on SIRT1/2/3,anticancer.</p>Formule :C18H15N3O4SDegré de pureté :99.97%Couleur et forme :SolidMasse moléculaire :369.39KDM5-C49
CAS :<p>KDM5-C49 is a potent and selective inhibitor of KDM5, which regulates cell proliferation and stem cell self-renewal and differentiation.</p>Formule :C15H24N4O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :308.38Dot1L-IN-2
CAS :<p>Dot1l-in-2 is an effective, selective and oral bioutilization inhibitor of histone methyltransferase Dot1L, with IC50 and Ki of 0.4 nM and 0.08 nM, respectively</p>Formule :C27H24N8ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :476.53CMP-5 hydrochloride
CAS :<p>CMP-5 hydrochloride: potent, selective PRMT5 inhibitor; inactive against PRMT1/4/7; blocks S2Me-H4R3 on histones.</p>Formule :C21H22ClN3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :351.87UMB-136
CAS :<p>UMB-136 is a bromodomain BRD4 inhibitor that acts by significantly inducing HIV-1 reactivation.</p>Formule :C24H27N5O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :417.5BRM/BRG1 ATP Inhibitor-3
CAS :<p>BRM/BRG1 ATP Inhibitor-3 targets BRM/BRG1 (IC50: 10.4/19.3 nM) for cancer/BAF disorder research.</p>Formule :C26H25N5O2S2Couleur et forme :SolidMasse moléculaire :503.64OTS186935
CAS :<p>OTS186935 is a inhibitor of protein methyltransferase SUV39H2(IC50 of 6.49 nM).</p>Formule :C25H26ClN5O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :463.96
