Chromatine/Épigénétique
Les inhibiteurs de la chromatine/épigénétique sont des composés qui modulent la structure et la fonction de la chromatine ou interfèrent avec les modifications épigénétiques, telles que la méthylation de l'ADN et la modification des histones. Ces inhibiteurs sont des outils essentiels pour étudier la régulation de l'expression génique et le rôle de l'épigénétique dans des maladies telles que le cancer, les troubles neurologiques et les anomalies du développement. En ciblant les processus épigénétiques, ces inhibiteurs peuvent modifier les schémas d'expression génique et offrir de nouvelles perspectives thérapeutiques. Chez CymitQuimica, nous offrons une large sélection d'inhibiteurs de la chromatine/épigénétique de haute qualité pour soutenir vos recherches en biologie moléculaire, génétique et épigénétique.
Sous-catégories appartenant à la catégorie "Chromatine/Épigénétique"
2613 produits trouvés pour "Chromatine/Épigénétique"
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CBP/p300-IN-10
CAS :CBP/p300-IN-10, potent EP300/CREBBP inhibitor; IC50: 26 nM/39 nM. Potential for cancer research.Formule :C25H24F5N5O3Couleur et forme :SolidMasse moléculaire :537.48PRMT5-IN-10
CAS :PRMT5-IN-10 exhibits promising structure-dependent inhibitory effect on the protein methyltransferase PRMT5:MEP50 complex.Formule :C13H17N5O4Couleur et forme :SolidMasse moléculaire :307.31Depudecin
CAS :Depudecin, a polyketide from Alternaria brassicicola, has an 11-carbon chain with two epoxides and six stereocenters, inhibits HDAC, and is anti-angiogenic.Formule :C11H16O4Couleur et forme :SolidMasse moléculaire :212.24NSD3-IN-2
CAS :NSD3-IN-2: Potent NSD3 inhibitor, IC50 17.97μM, halts NSCLC growth (H460, H1299, H1650) with anticancer effects.Formule :C17H15N5OSCouleur et forme :SolidMasse moléculaire :337.4MAT2A-IN-4
CAS :MAT2A-IN-4 can be used for the cancer research that is an inhibitor of methionine adenosyltransferase 2A (MAT2A)[1].Formule :C18H16ClN3OCouleur et forme :SolidMasse moléculaire :325.79NSD3-IN-3
CAS :"NSD3-IN-3, a potent anticancer agent, inhibits NSD3 (IC50: 1.86 μM) and hampers H460 lung cancer cell growth."Formule :C15H17N5O2SCouleur et forme :SolidMasse moléculaire :331.39SYK/JAK-IN-1
CAS :SYK/JAK-IN-1 is a dual SYK/JAK inhibitor with IC50 values of less than 5 nM for both SYK and JAK2.Formule :C24H26N8O3Couleur et forme :SolidMasse moléculaire :474.52HDAC-IN-43
CAS :HDAC-IN-43: potent HDAC 1/3/6 inhibitor (IC50: 82 nM HDAC1, 45 nM HDAC3, 24 nM HDAC6); weak PI3K/mTOR (IC50: 3.6μM, 3.7μM); anti-proliferative.Formule :C22H28N6O4Couleur et forme :SolidMasse moléculaire :440.5NC-III-49-1
CAS :NC-III-49-1: potent BET inhibitor, binds BRD4/BRDT, inhibits cell growth, reduces c-Myc expression.Formule :C44H50N4O11S2Couleur et forme :SoildMasse moléculaire :875.02HDAC-IN-44
CAS :HDAC-IN-44 is an HDAC inhibitor (IC50: 61.2 nM) with strong anti-cancer effects.Formule :C26H27BrN4O4Couleur et forme :SolidMasse moléculaire :539.42SIRT1-IN-2
CAS :SIRT1-IN-2 (compound 3h) is a potent and selective inhibitor of SIRT1 (silent information regulator 1) with an IC 50 of 1.6 μM [1].Formule :C13H15ClN2OCouleur et forme :SolidMasse moléculaire :250.72BET bromodomain inhibitor 2
CAS :BET bromodomain inhibitor 2 is a potent inhibitor of the BET-type bromodomain (IC50: 14.1 μM).Formule :C23H30N2O5SCouleur et forme :SolidMasse moléculaire :446.56GDC-4379
CAS :GDC-4379 is a JAK1 inhibitor that can be used to study asthma.Formule :C21H18ClF2N7O3Couleur et forme :SolidMasse moléculaire :489.86HDAC6-IN-10
CAS :HDAC6-IN-10 is a potent HDAC6 inhibitor with 0.73 nM IC50, highly selective, and hinders multiple myeloma cell growth.Formule :C21H20N4O4Couleur et forme :SolidMasse moléculaire :392.41HDAC6-IN-46
CAS :HDAC6-IN-46 (compound 12) is a selective inhibitor of histone deacetylase 6 (HDAC6), exhibiting an IC50 of 6.2 nM. It is utilized in research related to Alzheimer's disease.Formule :C26H21N3O4Couleur et forme :SolidMasse moléculaire :439.46MAT2A-IN-5
CAS :MAT2A-IN-5 inhibits MAT2A in tumors, curbing growth in gastric, colon, liver, and pancreatic cancers.Formule :C17H12ClF3N2OCouleur et forme :SolidMasse moléculaire :352.74SIRT6-IN-1
CAS :SIRT6-IN-1, a novel SIRT6 inhibitor, reduces glycemia and improves oral glucose tolerance in unfed wild-type mice.Formule :C19H14N4O5SCouleur et forme :SolidMasse moléculaire :410.4EZH2-IN-7
CAS :EZH2-IN-7 inhibits EZH2, reducing H3K27me3 and tumor growth (e.g., breast, prostate cancer, leukemia). Potential in cancer research.Formule :C31H37D2N5O3SCouleur et forme :SolidMasse moléculaire :563.755-Aza-4'-thio-2'-deoxycytidine
CAS :5-Aza-4'-thio-2'-deoxycytidine (5-Aza-T-dCyd), a sulfur-containing deoxy-cytidine analog, serves as an orally active inhibitor of DNA methyltransferase I (DNMT1). It exhibits potential antitumor effects and DNA hypomethylating properties [1].Formule :C8H12N4O3SCouleur et forme :SolidMasse moléculaire :244.27G9a-IN-2
CAS :G9a-IN-2 (Compound 7i) is an inhibitor of the histone methyltransferase G9a, with an IC50 of 0.024 μM. It can reduce the levels of H3K9me2 and induce the expression of γ-globin mRNA. G9a-IN-2 shows potential for improving Sickle Cell Disease (SCD).Formule :C30H42N4O4Couleur et forme :SolidMasse moléculaire :522.68FAK/aurora kinase-IN-1
CAS :FAK/aurora kinase-IN-1, a dual inhibitor of FAK and aurora kinase, has IC50 values of 6.61 nM and 0.91 nM respectively, and demonstrates anticancer effects (WO2018019252A1; compound 11) [1].Formule :C23H24ClN7O3Couleur et forme :SolidMasse moléculaire :481.93HDAC-IN-30
CAS :HDAC-IN-30 is a potent HDAC inhibitor targeting HDAC1, 2, 3, 6, and 8 with strong antitumor efficacy.
Formule :C22H23N5O3Couleur et forme :SolidMasse moléculaire :405.45ML753286
CAS :ML753286 has high permeability and low to medium clearance in rodent and human liver S9 fractions.Formule :C20H25N3O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :355.43EZM 2302
CAS :EZM 2302 (GSK3359088) is a selective, and orally available arginine methyltransferase CARM1 inhibitor (IC50: 6 nM).Cost-effective and quality-assured.Formule :C29H37ClN6O5Degré de pureté :97.47% - ≥98%Couleur et forme :SolidMasse moléculaire :585.09NSC 698600
CAS :NSC 698600 is a potent inhibitor of PCAF(p300/CBP-associated factor) with IC 50 of 6.51 μM that shows good inhibition activity of cancer cell proliferation [1].Formule :C14H12N2O2SCouleur et forme :SolidMasse moléculaire :272.32SPC-180002
CAS :SPC-180002, a dual SIRT1/3 inhibitor, exhibits IC50 values of 1.13 and 5.41 μM for SIRT1 and SIRT3, respectively.Formule :C18H23NO4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :317.38HPCG
CAS :HPCG is an inhibitor of HIF-1α prolyl hydroxylase.Formule :C8H8N2O4Couleur et forme :SolidMasse moléculaire :196.16Sirtuin modulator 4
CAS :Sirtuin modulator 4 inhibits SIRT1 (EC50: 51-100 μM), may extend cell life and prevent diseases like diabetes and cancer.Formule :C18H10N2O2SCouleur et forme :SolidMasse moléculaire :318.35KU-0058684
CAS :KU-0058684 is a potent PARP and DNA-PK inhibitors.Formule :C19H14FN3O3Couleur et forme :SolidMasse moléculaire :351.33ZIKV-IN-2
CAS :ZIKV-IN-2 blocks ZIKV replication, is a strong NS5 MTase inhibitor (IC50: 38.86 μM), and aids Zika virus research.Formule :C39H42O4Couleur et forme :SolidMasse moléculaire :574.75iBRD4-BD1
CAS :iBRD4-BD1 inhibits BRD4 bromodomain selectively with 12 nM IC50, useful in inflammation and cancer research.Formule :C29H30F3N5OCouleur et forme :SolidMasse moléculaire :521.58GNA002
CAS :GNA002 is a highly potent, specific, and covalent EZH2 (Enhancer of zeste homolog 2) inhibitor (IC50: 1.1 μM).Formule :C42H55NO8Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :701.89CPI-905
CAS :CPI-905 is a potent and selective EZH2 inhibitor with IC50 value of 39.5 nM.Formule :C18H20N2O5Couleur et forme :SolidMasse moléculaire :344.36ZLD1039
CAS :ZLD1039, an oral EZH2 inhibitor, shows strong PRC2 inhibition at low nanomolar IC50s, and halts breast cancer growth and spread.Formule :C36H48N6O3Degré de pureté :99.5%Couleur et forme :SolidMasse moléculaire :612.8Binucleine 2
CAS :Binucleine 2: Drosophila Aurora B kinase inhibitor (Ki=0.36μM), dose-dependent, minimal effect on human/X. laevis kinases, disrupts mitosis in fly cells.Formule :C13H11ClFN5Couleur et forme :SolidMasse moléculaire :291.71UMB-32
CAS :UMB-32: Potent, selective BRD4 inhibitor, Kd 550 nM, IC50 637 nM, also targets TAF1.Formule :C21H23N5OCouleur et forme :SolidMasse moléculaire :361.44Bromodomain inhibitor-10
CAS :Bromodomain inhibitor-10 (compound 128) suppresses BRD4-1/2 with Kd 15 nM/2.5 μM and curbs IL12p40 production.Formule :C20H20N4O3Couleur et forme :SolidMasse moléculaire :364.4FNDR-20123 free base
CAS :FNDR-20123 is a safe, oral first-in-class anti-malarial HDAC inhibitor with low IC50s against Plasmodium and human HDACs.Formule :C21H23N5O2Couleur et forme :SolidMasse moléculaire :377.44CAY10669
CAS :CAY10669 inhibits PCAF (IC50 = 662 μM), is twice as potent as anacardic acid, and reduces H4 acetylation in HepG2 cells at 30-60 μM.Formule :C20H22O4Couleur et forme :SolidMasse moléculaire :326.39OM-137
CAS :OM137 inhibits Aurora kinases, impedes cell growth at high doses, and enhances low-dose paclitaxel effects.Formule :C13H14N4O3SCouleur et forme :SolidMasse moléculaire :306.34UNC6212 (Kme2)
UNC6212 (Kme2), a dimethyllysine (Kme2)-containing ligand, has a K D for CBX5 of 5.7 μM .Formule :C39H53N7O11Couleur et forme :SolidMasse moléculaire :795.88TC-E 5001
CAS :dual tankyrase (TNKS) inhibitorFormule :C20H19N5O3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :409.46BET-BAY 002 (S enantiomer)
CAS :The S-enantiomer of BET-BAY 002, referred to as BET-BAY 002 S enantiomer, is a potent inhibitor of BET (Bromodomain and Extra-Terminal motif proteins).Formule :C22H18ClN5ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :403.86Bromodomain IN-1
CAS :Bromodomain IN-1 is an inhibitor of Bromodomain.Formule :C22H23ClN4O3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :458.96BAY-598 R-isomer
CAS :BAY-598 R-isomer, a SMYD2-selective inhibitor, is the R-enantiomer of BAY589, not targeting PAR1.Formule :C22H20Cl2F2N6O3Couleur et forme :SolidMasse moléculaire :525.34JAK3/BTK-IN-2
CAS :JAK3/ BTk-in-2 is a potent JAK3/BTK inhibitor.
Formule :C25H32N8O2Degré de pureté :99.64% - 99.87%Couleur et forme :SolidMasse moléculaire :476.57HDAC/CK2-IN-1
CAS :HDAC/CK2-IN-1 (compound 38) acts as an inhibitor of HDAC1 (IC 50 = 1.46 μM), HDAC6 (IC 50 = 0.66 μM), and CK2 (IC 50 = 3.67 μM). It demonstrates promising antiproliferative effects on various cell lines, including Jurkat, MCF-7, HCT-116, and HL-60.Formule :C15H18Br4N4O2Couleur et forme :SolidMasse moléculaire :605.95PARP-2/1-IN-2
CAS :PARP-2/1-IN-2, Veliparib's enantiomer, inhibits PARP-1/2 (Ki: 5/2 nM) with 3 nM EC50 in cell assay.Formule :C13H16N4OCouleur et forme :SolidMasse moléculaire :244.29HDAC/NAMPT-IN-1
CAS :HDAC/NAMPT-IN-1 (compound 39h) simultaneously inhibits HDAC and NAMPT, exhibiting IC 50 values ranging from 0.72 to 37081 nM for HDAC and 1618 nM for NAMPT [1].Formule :C19H21N5O2Couleur et forme :SolidMasse moléculaire :351.4Tyk2-IN-5
CAS :Tyk2-IN-5 is a selective and orally active inhibitor of Tyk2 JH2 (Ki: 0.086 nM for Tyk2 JH2; IC50: 25 nM for IFNα).Formule :C21H19FN8O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :434.43DDO-2093 dihydrochloride
DDO-2093 dihydrochloride: potent MLL1-WDR5 inhibitor, IC50=8.6 nM, Kd=11.6 nM, antitumor.Formule :C29H39Cl3FN9O3Couleur et forme :SolidMasse moléculaire :687.04UNC0379 TFA
CAS :UNC0379 TFA inhibits SETD8 (IC50: 7.3 μM), selective for 15+ methyltransferases.Formule :C25H36F3N5O4Couleur et forme :SolidMasse moléculaire :527.589IACS-9571
CAS :IACS-9571 is a selective and potent inhibitor of TRIM24 and BRPF1, (IC50: 8 nM for TRIM24; Kds: 31 nM and 14 nM for TRIM24 and BRPF1).Formule :C32H42N4O8SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :642.76YM-53601
CAS :YM-53601 is an SQS inhibitor that inhibits adipogenic biosynthesis and lipid secretion in rodents.YM-53601 is a cholesterol-lowering agent that inhibits FDFT1.Formule :C21H22ClFN2ODegré de pureté :99.65%Couleur et forme :SolidMasse moléculaire :372.86MI-2-2
CAS :MI-2-2 is an inhibitor of bivalent protein-protein interaction between menin and MLL with an IC50 of 46 nM. MI-2-2 binds to menin with Kd of 22 nM.Formule :C17H20F3N5S2Degré de pureté :99.65%Couleur et forme :SolidMasse moléculaire :415.5CX-6258
CAS :CX-6258 is an orally valid Pim 1/2/3 kinase(IC50=5 nM/25 nM/16 nM) inhibitor. It has good biological activity and kinase specificity.Formule :C26H24ClN3O3Degré de pureté :97.46%Couleur et forme :SolidMasse moléculaire :461.94Ref: TM-T1834
1mg34,00€5mg75,00€10mg101,00€25mg197,00€50mg295,00€100mg447,00€200mg623,00€1mL*10mM (DMSO)77,00€Furamidine dihydrochloride
CAS :Furamidine dihydrochloride is a cell-permeable, selective PRMT1 inhibitor that also binds AT-rich DNA. It blocks proliferation in leukemia cell lines.Formule :C18H18Cl2N4ODegré de pureté :98.16%Couleur et forme :SolidMasse moléculaire :377.27F-amidine
CAS :F-amidine is a bioavailable irreversible PAD4 inactivator.Formule :C14H19FN4O2Couleur et forme :SolidMasse moléculaire :294.32KD 5170
CAS :KD 5170, a pan inhibitor of histone deacetylases (HDACs), demonstrates widespread antitumor activity both in vitro and in vivo [1].Formule :C20H25N3O5S2Couleur et forme :SolidMasse moléculaire :451.56PI3K/Akt/CREB activator 1
CAS :PI3K/Akt/CREB activator 1 (AE-18) is an iNOS inhibitor that can be used to study vascular dementia and Parkinson's.Formule :C19H15F4NO3Couleur et forme :SolidMasse moléculaire :381.32JAK3-IN-1
CAS :JAK3-IN-1 is an orally active, selective and potent JAK3 inhibitor for the study of immune system disorders.Formule :C26H30ClN7O2Couleur et forme :SolidMasse moléculaire :508.02TAK-418
CAS :TAK-418 is an orally active LSD1/KDM1A inhibitor with a 2.9 nM IC50, potential for autism therapy.Formule :C17H25ClN2O2SDegré de pureté :99.69%Couleur et forme :SolidMasse moléculaire :356.91Ref: TM-T39252
1mg131,00€5mg313,00€10mg494,00€25mg1.009,00€50mg1.359,00€100mg1.818,00€200mg2.457,00€1mL*10mM (DMSO)366,00€TUL01101
CAS :TUL01101, a selective oral JAK1 inhibitor (IC50: 3 nM), also targets JAK2, JAK3, TYK2; for rheumatoid arthritis research.Formule :C22H25F2N5O2Couleur et forme :SolidMasse moléculaire :429.46LSD1-IN-13
CAS :LSD1-IN-13, an oral LSD1 blocker (IC50: 24.43 nM), boosts CD86 (EC50: 470 nM), and triggers AML cell line differentiation.Formule :C23H29N3O2SCouleur et forme :SolidMasse moléculaire :411.56SIRT5 inhibitor 4
CAS :SIRT5 inhibitor 4 (compound 11) is a dose-dependent and selective SIRT5 (Sirtuin5) inhibitorand no inhibitory effect on SIRT1/2/3,anticancer.Formule :C18H15N3O4SDegré de pureté :99.97%Couleur et forme :SolidMasse moléculaire :369.39WD2000-012547
CAS :WD2000-012547 is a selective inhibitor of poly(ADP-ribose)-polymerase (PARP-1) (pKi: 8.221).Formule :C17H14N2ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :262.31BI-9321
CAS :BI-9321: Selective NSD3-PWWP1 antagonist, Kd 166 nM. Inactive against NSD2-PWWP1/NSD3-PWWP2.Formule :C22H21FN4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :360.43SIRT5 inhibitor 6
CAS :SIRT5 inhibitor 6 is Sirtuin 5 inhibitor for sepsis-associated acute kidney injury (AKI) modulates protein succinylation and pro-inflammatory cytokine release.Formule :C21H28N6O4SDegré de pureté :99.84%Couleur et forme :SolidMasse moléculaire :460.55SHP2/HDAC-IN-1
CAS :SHP2/HDAC-IN-1: dual SHP2/HDAC inhibitor, IC50: 20.4 nM/25.3 nM, boosts antitumor immunity, aids cancer immunotherapy research.Formule :C34H35Cl2N7O3Couleur et forme :SolidMasse moléculaire :660.59BiBET
CAS :BiBET is a potent, selective, bivalent inhibitor of BET bromodomains.Formule :C26H30N10O3Couleur et forme :SolidMasse moléculaire :530.58NSD3-IN-1
CAS :NSD3-IN-1, a histone methyltransferase NSD3 inhibitor, demonstrates an IC50 of 28.58 μM.Formule :C13H13N5OSCouleur et forme :SolidMasse moléculaire :287.34OXF BD 02
CAS :OXF BD 02 is a potent and selective BRD4(1) inhibitor (IC50: 382 nM) with anticancer and anti-inflammatory activity.Formule :C18H17NO3Degré de pureté :98.25%Couleur et forme :SolidMasse moléculaire :295.33Cedazuridine
CAS :Cedazuridine ((4R)-2'-Deoxy-2',2'-difluoro-3,4,5,6-tetrahydrouridine) is an oral inhibitor of cytidine deaminase with antineoplastic properties.Formule :C9H14F2N2O5Degré de pureté :99.66%Couleur et forme :SolidMasse moléculaire :268.21Bobcat339 hydrochloride
CAS :Bobcat339 hydrochloride is a 10 11 translocation (TET) dioxygenase inhibitor that inhibits both TET1 and TET2.Formule :C16H13Cl2N3ODegré de pureté :99.22%Couleur et forme :SolidMasse moléculaire :334.2Ref: TM-T61012
2mg34,00€5mg50,00€10mg80,00€25mg152,00€50mg236,00€100mg353,00€200mg517,00€1mL*10mM (DMSO)55,00€SIRT6-IN-5
CAS :SIRT6-IN-5: potent, selective SIRT6 inhibitor; IC50=34 μM; immunosuppressive, enhances chemo, boosts H3K9 acetylation, glucose uptake, curbs T-cell growth.Formule :C19H14N2O6Degré de pureté :98.77%Couleur et forme :SolidMasse moléculaire :366.32CMP-5
CAS :CMP-5 is a PRMT5 inhibitor with antiviral activity, inhibits PRMT5 methyltransferase activity, and can be used in the study of SARS virus infection.Formule :C21H21N3Degré de pureté :98.68%Couleur et forme :SolidMasse moléculaire :315.41Ref: TM-T10850
1mg44,00€5mg92,00€10mg137,00€25mg225,00€50mg334,00€100mg494,00€500mg1.054,00€1mL*10mM (DMSO)101,00€CEP-9722
CAS :CEP-9722 is a PARP-1 and PARP-2 inhibitor with anticancer activity and is used in the study of ovarian cancer.Formule :C24H26N4O3Degré de pureté :98.38% - 98.56%Couleur et forme :SolidMasse moléculaire :418.49LSD1-IN-20
CAS :LSD1-IN-20: Dual LSD1/G9a inhibitor, Ki 0.44/0.68 μM; hampers THP-1, MDA-MB-231 cell growth with IC50 0.51/1.60 μM at 72h.Formule :C27H38N6O2Degré de pureté :97.17% - 99.57%Couleur et forme :SolidMasse moléculaire :478.63SIRT5 inhibitor 1
CAS :SIRT5 inhibitor 1 targets human Sirtuin 5 deacylase, with an IC50 of 0.11 μM, linked to aging diseases.Formule :C31H39FN6O6S2Degré de pureté :97.8%Couleur et forme :SolidMasse moléculaire :674.81Ref: TM-T12921
1mg138,00€2mg197,00€5mg334,00€10mg502,00€25mg884,00€50mg1.288,00€100mg1.728,00€1mL*10mM (DMSO)442,00€TGP-377/421
CAS :TGP-377/421 (Targapre-miR-377/421) is a potent miR-377 and miR-421 dual inhibitor that inhibits miR-377 and miR-421 by binding to their functional sites.Formule :C20H16N6Degré de pureté :97.02%Couleur et forme :SolidMasse moléculaire :340.38Ref: TM-T61085
1mg63,00€5mg137,00€10mg215,00€25mg430,00€50mg695,00€100mg973,00€500mg1.945,00€1mL*10mM (DMSO)150,00€EZH2-IN-13
CAS :EZH2-IN-13 is a potent EZH2 inhibitor with potential anticancer activity.EZH2-IN-13 may be used to study diseases associated with EZH2 activity.Formule :C34H45N5O3Degré de pureté :98.3%Couleur et forme :SolidMasse moléculaire :571.75AGI-43192
CAS :AGI-43192: potent MAT2A inhibitor, crosses blood-brain barrier, may help study SAM in CNS and treat cancer.Formule :C23H16ClF3N6ODegré de pureté :99.89%Couleur et forme :SolidMasse moléculaire :484.86Ref: TM-T9729
1mg72,00€5mg161,00€10mg250,00€25mg411,00€50mg577,00€100mg772,00€500mg1.558,00€1mL*10mM (DMSO)172,00€Corin
CAS :Corin is an irreversible inhibitor of HDAC1(IC50 = 147 nM) and LSD1(Ki = 110 nM).Formule :C26H28N4O2Degré de pureté :99.6%Couleur et forme :SolidMasse moléculaire :428.53Ref: TM-T10864
1mg167,00€5mg409,00€10mg605,00€25mg954,00€50mg1.288,00€100mg1.728,00€1mL*10mM (DMSO)442,00€GRK6-IN-1
CAS :GRK6-IN-1 (compound 18) is a potent GRK6 blocker, with an IC50 of 120 nM, showing promise for multiple myeloma research.Formule :C22H23ClN6O2Degré de pureté :99.37%Couleur et forme :SolidMasse moléculaire :438.91Ref: TM-T62518
1mg54,00€5mg114,00€10mg178,00€25mg409,00€50mg708,00€100mg1.153,00€1mL*10mM (DMSO)126,00€Crebinostat
CAS :Crebinostat: potent HDAC inhibitor, boosts synapsin-1 in neurons, enhances memory and gene Egr1 expression in mice.Formule :C20H23N3O3Degré de pureté :99.49%Couleur et forme :SolidMasse moléculaire :353.41CD532
CAS :CD532: Potent Aurora A inhibitor, IC50=45 nM, blocks kinase activity, degrades MYCN, interacts with AURKA, studies cancer.Formule :C26H25F3N8ODegré de pureté :99.99%Couleur et forme :SolidMasse moléculaire :522.52TNG908
CAS :TNG908, a brain-penetrant PRMT5 inhibitor, is 15x more selective for MTAP mutant vs WT lines, useful in cancer studies.Formule :C21H23N5O2SDegré de pureté :98.08% - 98.24%Couleur et forme :SolidMasse moléculaire :409.51Ref: TM-T73494
1mg66,00€5mg145,00€10mg224,00€25mg358,00€50mg512,00€100mg707,00€1mL*10mM (DMSO)158,00€CARM1-IN-1
CAS :CARM1-IN-1 (CARM1-IN-7G) is a selective inhibitor of CARM1 with IC50 of 8.6 μM. CARM1-IN-1 shows weak activity against PRMT1 and SET7 with IC50 > 600 μM.Formule :C26H21Br2NO3Degré de pureté :98.24%Couleur et forme :SolidMasse moléculaire :555.26Ref: TM-T10682L
1mg34,00€5mg84,00€10mg120,00€25mg236,00€50mg385,00€100mg600,00€200mg837,00€1mL*10mM (DMSO)92,00€NSC 694623
CAS :NSC 694623: Potent HAT inhibitor, IC50=15.9 μM against PCAF, anti-cancer properties.Formule :C16H16N2OSDegré de pureté :99.9%Couleur et forme :SolidMasse moléculaire :284.38DCPLA-ME
CAS :DCPLA-ME (2-[(2-Pentylcyclopropyl)methyl]cyclopropaneoctanoic acid methyl ester) is the methyl ester form of DCPLA and can be used to treat neurodegenerativeFormule :C21H38O2Degré de pureté :99.80%Couleur et forme :SolidMasse moléculaire :322.53Ref: TM-T10980
1mg62,00€5mg126,00€10mg172,00€25mg350,00€50mg572,00€100mg772,00€200mg1.054,00€1mL*10mM (DMSO)138,00€HDAC8-IN-20a
CAS :HDAC8-IN-20a (HDAC8 inhibitor-20a) is a potent and selective HDAC8 inhibitor with an IC50 of 27 nM.Formule :C15H15NO4Degré de pureté :98.24% - 99.22%Couleur et forme :SolidMasse moléculaire :273.28Ref: TM-T24133
1mg173,00€5mg424,00€10mg585,00€25mg873,00€50mg1.134,00€100mg1.468,00€200mg1.963,00€1mL*10mM (DMSO)380,00€HDAC6 degrader 9c
CAS :HDAC6 degrader 9c is a small molecule histone deacetylase 6 (HDAC6) degrader that can be used to study cancer or other diseases.Formule :C37H45N9O10Degré de pureté :>99.99%Couleur et forme :SolidMasse moléculaire :775.81ACY-1083
CAS :ACY-1083 is a selective and brain-penetrating HDAC6 inhibitor (IC50: 3 nM) and effectively reverses chemotherapy-induced peripheral neuropathy.Formule :C17H18F2N4O2Degré de pureté :99.19% - 99.43%Couleur et forme :SolidMasse moléculaire :348.35Ref: TM-T10244
1mg144,00€5mg295,00€10mg504,00€25mg795,00€50mg1.108,00€100mg1.494,00€500mg2.997,00€1mL*10mM (DMSO)326,00€LEM-14
CAS :LEM-14 is a potent NSD2-specific inhibitor (IC50:132 μM).LEM-14 may be used in the study of multiple myeloma.
Formule :C25H26N4O4SDegré de pureté :98.3%Couleur et forme :SolidMasse moléculaire :478.56GSK-690
CAS :GSK-690 is a potent, reversible and selective inhibitors of Lysine Specific Demethylase 1.Formule :C24H23N3ODegré de pureté :98.65%Couleur et forme :SolidMasse moléculaire :369.46R 59-022 hydrochloride
CAS :R 59-022 hydrochloride is a 5-HT antagonist, PKC activator, DGK inhibitor (IC50: 2.8 µM), and modulates lipid production in platelets and neutrophils.
Formule :C27H27ClFN3OSDegré de pureté :97.7%Couleur et forme :SolidMasse moléculaire :496.04ZEN-3219
CAS :ZEN-3219 is a BET inhibitor, which has inhibitory effect on BRD4(BD1), BRD4(BD2) and BRD4(BD1BD2).Formule :C19H18N2O3Degré de pureté :99.86%Couleur et forme :SolidMasse moléculaire :322.36Givinostat hydrochloride
CAS :Givinostat HCl (ITF2357 HCl) inhibits HDAC1/3 (IC50: 198/157 nM) with anti-inflammatory, anti-angiogenic, and antineoplastic properties.Formule :C24H28ClN3O4Degré de pureté :99.39%Couleur et forme :SolidMasse moléculaire :457.95Ref: TM-T6279L
1mg35,00€5mg75,00€10mg120,00€25mg240,00€50mg416,00€100mg663,00€200mg888,00€1mL*10mM (DMSO)77,00€TM2-115
CAS :TM2-115 is a inhibitor of malaria parasite histone methyltransferases that results in rapid and irreversible parasite death [1].Formule :C28H38N6O2Degré de pureté :97.67%Couleur et forme :SolidMasse moléculaire :490.64MAT2A-IN-9
CAS :MAT2A-IN-9, a 2-oxoquinazoline, inhibits MAT2A with antitumor effects on lymphomas and solid cancers.Formule :C14H8ClF3N4ODegré de pureté :99.17%Couleur et forme :SolidMasse moléculaire :340.69
