Chromatine/Épigénétique
Les inhibiteurs de la chromatine/épigénétique sont des composés qui modulent la structure et la fonction de la chromatine ou interfèrent avec les modifications épigénétiques, telles que la méthylation de l'ADN et la modification des histones. Ces inhibiteurs sont des outils essentiels pour étudier la régulation de l'expression génique et le rôle de l'épigénétique dans des maladies telles que le cancer, les troubles neurologiques et les anomalies du développement. En ciblant les processus épigénétiques, ces inhibiteurs peuvent modifier les schémas d'expression génique et offrir de nouvelles perspectives thérapeutiques. Chez CymitQuimica, nous offrons une large sélection d'inhibiteurs de la chromatine/épigénétique de haute qualité pour soutenir vos recherches en biologie moléculaire, génétique et épigénétique.
Sous-catégories appartenant à la catégorie "Chromatine/Épigénétique"
2616 produits trouvés pour "Chromatine/Épigénétique"
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Fagaronine chloride
CAS :Fagaronine chloride is a potent inhibitor of Topoisomerases I.Formule :C21H20ClNO4Couleur et forme :SolidMasse moléculaire :385.845-Octyl-α-ketoglutarate
CAS :In addition to its role in the Krebs cycle, α-ketoglutarate (2-oxoglutarate) has roles as a substrate or modulator of enzymes.Formule :C13H22O5Couleur et forme :SolidMasse moléculaire :258.31PI3K/Akt/CREB activator 1
CAS :PI3K/Akt/CREB activator 1 (AE-18) is an iNOS inhibitor that can be used to study vascular dementia and Parkinson's.Formule :C19H15F4NO3Couleur et forme :SolidMasse moléculaire :381.32KF 13218
CAS :KF 13218 is a selective, potent and long lasting thromboxane B2 (TXB2) synthase inhibitor with an IC50 value of 5.3±1.3 nM.Formule :C20H20N2O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :336.38Y06036
CAS :Y06036, a potent and selective BET inhibitor, can bind to the BRD4(1) bromodomain (Kd: 82 nM).Formule :C16H15BrN2O5SDegré de pureté :99.97%Couleur et forme :SolidMasse moléculaire :427.27Lobelane Hydrochloride
CAS :Lobelane Hydrochloride is a vesicular monoamine transporter-2 (VMAT2) inhibitor.Formule :C22H30ClNCouleur et forme :SolidMasse moléculaire :343.93Bizine dihydrochloride
CAS :Bizine dihydrochloride is a potent LSD1 inhibitor in vitro, being selective versus monoamine oxidases A/B and the LSD1 homologue, LSD2.Formule :C18H25Cl2N3OCouleur et forme :SolidMasse moléculaire :370.32CPI703
CAS :CPI703 is a novel potent and specific CBP/EP300 bromodomain inhibitor.Formule :C17H22N4ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :298.38PRMT5-IN-2
CAS :PRMT5-IN-2 is an inhibitor of protein arginine methyltransferase 5.Formule :C17H16ClFN4O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :394.78(Rac)-BAY1238097
CAS :(Rac)-BAY1238097 is a inhibitor of BET(IC50 of 1.02 μM for BRD4),used in cancer research.Formule :C25H33N5O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :451.56Bizine
CAS :Bizine, a Phenelzine analogue, selectively inhibits LSD1 (Ki=59 nM), modulates histone methylation in cancer, and may have neuroprotective uses.Formule :C18H23N3OCouleur et forme :SolidMasse moléculaire :297.39EP009
CAS :EP009, a novel, selective, and orally active inhibitor of JAK3, induces therapeutic response in T-cell malignancies.Formule :C14H24O2Couleur et forme :SolidMasse moléculaire :224.34HDAC ligand-1
CAS :HDAC ligand-1 is a synthetic precursor utilized in the production of PROTAC-based HDAC degraders [1].Formule :C7H8N2ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :136.15Eleven-Nineteen-Leukemia Protein IN-1
CAS :ENL-IN-1: Potent ENL YEATS domain inhibitor with 14.5 nM IC50, enhances thermal stability in vitro.Formule :C27H33N7O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :487.6PRMT5:MEP50 PPI
PRMT5:MEP50 PPI inhibitor with anti-tumor and anti-proliferative effects on lung and prostate cancers.Formule :C24H22N4O4Couleur et forme :SolidMasse moléculaire :430.46SirReal-1
CAS :SirReal-1 is an effective and selective inhibitor of Sirt2.Formule :C18H18N4OS2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :370.49KBH-A42
CAS :KBH-A42 is an inhibitor of histone deacetylase.Formule :C17H22N2O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :302.37SRI-42127
CAS :SRI-42127 is a novel small molecule inhibitor of the RNA regulatory factor HuR that inhibits tumor growth and reduces neuropathic pain following nerve injury.Formule :C19H20N6ODegré de pureté :99.66%Couleur et forme :SolidMasse moléculaire :348.4Prospasmine
CAS :Prospasmine is an anticholinergic.Formule :C17H28ClNO2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :313.87CAY10727
CAS :CAY10727 selectively inhibits PAD3 (15,600 M^-1min^-1) over PAD1, PAD2, and PAD4.Formule :C21H22Cl2N4O2Couleur et forme :SolidMasse moléculaire :433.33HDAC6-IN-46
CAS :HDAC6-IN-46 (compound 12) is a selective inhibitor of histone deacetylase 6 (HDAC6), exhibiting an IC50 of 6.2 nM. It is utilized in research related to Alzheimer's disease.Formule :C26H21N3O4Couleur et forme :SolidMasse moléculaire :439.46NL-103
CAS :NL-103, a dual-targeting compound, inhibits HDACs & Hh pathway, countering vismodegib-resistant Smo mutations.Formule :C26H27Cl2N5O4Couleur et forme :SolidMasse moléculaire :544.43EPZ033294
CAS :EPZ033294 has potential anticancer and antiproliferative activity.Formule :C20H22ClN7ODegré de pureté :99.95%Couleur et forme :SolidMasse moléculaire :411.89TK4g
CAS :TK4g, a potent JAK inhibitor, has IC50s of 12.61 nM (JAK2) & 15.80 nM (JAK3); promising for lymphoid diseases & leukemia research.Formule :C19H19N3O4SCouleur et forme :SolidMasse moléculaire :385.44DS-437
CAS :DS-437 is a dual PRMT5/7 inhibitor (IC50s: 6 μM). DS-437 also inhibits DNMT3A and DNMT3B (IC50s: 52 and 62 μM). DS-437 inhibits the methylation of FOXP3.Formule :C15H23N7O4SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :397.45Hns 32
CAS :Hns 32 possesses antiarrhythmic properties in dog and guinea pig hearts. It also has vasodilator action.Formule :C24H29N3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :359.51Guadecitabine sodium
CAS :Guadecitabine sodium is a inhibitor of second-generation DNA methyltransferases (DNMT) .Formule :C18H24N9NaO10PDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :580.407AMPK activator 1
CAS :AMPK activator 1 is an AMPK activator(compound No.1-75, EC50: <0.1μM).Formule :C32H33F3N4O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :578.62HDAC6-IN-5
CAS :HDAC6-IN-5 (11b), potent HDAC6 blocker, crosses BBB, IC50: 0.025μM, hinders Aβ1-42/AChE aggregation, boosts neurites, low toxicity.Formule :C20H14BrN3O2Couleur et forme :SolidMasse moléculaire :408.25JJO-1
CAS :JJO-1 is a bi-quinoline activating all AMPK αβγ isoforms except γ3; it requires low ATP and is unaffected by γ mutations or β deletions.Formule :C19H13N3Couleur et forme :SolidMasse moléculaire :283.33Angiogenesis agent 1
CAS :Compound C-31, a salidroside-based glycoside, activates HIF-1α and may aid in diabetic limb ischemia studies.Formule :C20H24O7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :376.4AZD-1897
CAS :AZD-1897 is a highly efficient ATP-competitive pan-PIM inhibitor with anti-cancer and anti-leukemia activity, used in multiple myeloma research.Formule :C18H23N3O3SDegré de pureté :99.49%Couleur et forme :SolidMasse moléculaire :361.46Tankyrase-IN-4
Tankyrase-IN-4 is a potent inhibitor of tankyrase 1 (TNKS1), exhibiting an IC50 of 0.8 nM, and is utilized in cancer research.Formule :C25H24N6O5Couleur et forme :SolidMasse moléculaire :488.5Vibsanin A
CAS :Vibsanin A, an activator of protein kinase C (PKC) and an inhibitor of HSP90, demonstrates anti-proliferative effects on human cancer cell lines.Formule :C25H38O4Couleur et forme :SolidMasse moléculaire :402.57BET bromodomain inhibitor 3
CAS :BET Bromodomain Inhibitor 3 is a BET bromodomain inhibitor with an inhibitory Ki value of >40 µM against BrdT.Formule :C18H17N3O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :339.35SIRT1-IN-2
CAS :SIRT1-IN-2 (compound 3h) is a potent and selective inhibitor of SIRT1 (silent information regulator 1) with an IC 50 of 1.6 μM [1].Formule :C13H15ClN2OCouleur et forme :SolidMasse moléculaire :250.72I-BET151 dihydrochloride
CAS :I-BET 151 dihydrochloride is a BET bromodomain inhibitor that prevents BET from recruiting to chromatin.Formule :C23H23Cl2N5O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :488.37BAY1238097
CAS :BAY1238097 is a BET inhibitor with anticancer activity and antiproliferative activity for the study of advanced refractory malignancies.Formule :C25H33N5O3Degré de pureté :98.1% - 98.79%Couleur et forme :SolidMasse moléculaire :451.56Ref: TM-T12660L
1mg49,00€5mg101,00€1mL*10mM (DMSO)113,00€10mg172,00€25mg355,00€50mg620,00€100mg1.044,00€200mg1.404,00€DM-NOFD
CAS :DM-NOFD is a cell penetrant prodrug of NOFD, which is a potent and selective inhibitor of an asparaginyl hydroxylase FIH (factor-inhibiting HIF).Formule :C13H15NO5Couleur et forme :SolidMasse moléculaire :265.26Aurora kinase inhibitor-10
CAS :Aurora kinase inhibitor-10 is an orally active Aurora B inhibitor (IC50: 8 nM) that exhibits antitumour effects.Formule :C21H19F5N6O4SCouleur et forme :SolidMasse moléculaire :546.47HDAC-IN-43
CAS :HDAC-IN-43: potent HDAC 1/3/6 inhibitor (IC50: 82 nM HDAC1, 45 nM HDAC3, 24 nM HDAC6); weak PI3K/mTOR (IC50: 3.6μM, 3.7μM); anti-proliferative.Formule :C22H28N6O4Couleur et forme :SolidMasse moléculaire :440.5HDAC-IN-49
HDAC-IN-49: potent, broad HDAC inhibitor; IC50s: 10-1880 nM for HDAC1-6; strong anti-leukemic, low toxicity to healthy cells.Formule :C26H27FN4O4Couleur et forme :SolidMasse moléculaire :478.52ZL0516
CAS :ZL0516, a chromone-based oral BRD4 BD1 inhibitor, shows potent in vivo efficacy and good pharmacokinetics, suggesting use in treating inflammation.Formule :C27H34N2O6Couleur et forme :SolidMasse moléculaire :482.57SYK/JAK-IN-1
CAS :SYK/JAK-IN-1 is a dual SYK/JAK inhibitor with IC50 values of less than 5 nM for both SYK and JAK2.Formule :C24H26N8O3Couleur et forme :SolidMasse moléculaire :474.52DCE_42
CAS :DCE_42 is a novel EZH2 inhibitor, it also displays significant anti-proliferation activity against lymphoma cell lines.Formule :C22H19N9O2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :473.51HDAC6-IN-6
CAS :HDAC6-IN-6: Potent HDAC6 blocker, BBB-permeable, IC50: 0.025μM; inhibits AChE, Aβ 1-42 aggregation; promotes neurite growth, low neurotoxicity.Formule :C20H15N3O2Couleur et forme :SolidMasse moléculaire :329.35MAT2A-IN-4
CAS :MAT2A-IN-4 can be used for the cancer research that is an inhibitor of methionine adenosyltransferase 2A (MAT2A)[1].Formule :C18H16ClN3OCouleur et forme :SolidMasse moléculaire :325.79BET-IN-2
CAS :BET-IN-2 is a BET inhibitor (IC50: 52 nM for BRD4-BD1).Formule :C23H29N3ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :363.5NCD38
CAS :NCD38 is a potent, selective LSD1 inhibitor.Formule :C37H37ClF3N3O4Degré de pureté :98.21% - 98.86%Couleur et forme :SolidMasse moléculaire :680.16PRMT4-IN-1
CAS :PRMT4-IN-1 is a selective inhibitor of PRMT4, demonstrating an IC50 value of 3.2 nM, and has been shown to reduce the relative viability of MCF7 cells [1].Formule :C23H28FN3ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :381.49Depudecin
CAS :Depudecin, a polyketide from Alternaria brassicicola, has an 11-carbon chain with two epoxides and six stereocenters, inhibits HDAC, and is anti-angiogenic.Formule :C11H16O4Couleur et forme :SolidMasse moléculaire :212.24PRMT5-IN-10
CAS :PRMT5-IN-10 exhibits promising structure-dependent inhibitory effect on the protein methyltransferase PRMT5:MEP50 complex.Formule :C13H17N5O4Couleur et forme :SolidMasse moléculaire :307.31CBP/p300-IN-10
CAS :CBP/p300-IN-10, potent EP300/CREBBP inhibitor; IC50: 26 nM/39 nM. Potential for cancer research.Formule :C25H24F5N5O3Couleur et forme :SolidMasse moléculaire :537.48PF-00956980
CAS :PF-00956980: reversible JAK inhibitor, IC50: JAK1 (2.2μM), JAK2 (23.1μM), JAK3 (59.9μM), for lung/skin inflammation research.Formule :C18H26N6OCouleur et forme :SolidMasse moléculaire :342.44ZLD2218
CAS :ZLD2218, a potent inhibitor of BRD4 with an IC50 value of 107 nM, has been demonstrated to mitigate kidney injury and fibrosis through extensive studies.Formule :C22H18N4OCouleur et forme :SolidMasse moléculaire :354.4dWIZ-1
CAS :dWIZ-1 ((rac)-dWIZ-1) is a potent WIZ molecular gel degrader tha induction of haemoglobin fetalis (HbF) in erythroblasts, sickle cell disease (SCD).Formule :C22H29N3O4Degré de pureté :92.87% - 92.87%Couleur et forme :SolidMasse moléculaire :399.48CPI-1612
CAS :CPI-1612: Oral EP300/CBP HAT inhibitor, IC50 8.1 nM, has anticancer properties.Formule :C27H26N6OCouleur et forme :SolidMasse moléculaire :450.53GPI-15427
CAS :GPI-15427: a potent PARP-1 inhibitor, crosses the blood-brain barrier, boosts TMZ's effects on CNS tumors, and sensitizes cancer to radiotherapy.Formule :C20H20N4O2Couleur et forme :SolidMasse moléculaire :348.4A2AAR/HDAC-IN-2
CAS :A2AAR/HDAC-IN-2: potent dual A2AAR/HDAC inhib., Ki 10.3 nM, IC50 18.5 nM, anti-tumor potential.Formule :C23H26N6O4Couleur et forme :SolidMasse moléculaire :450.49CAY10722
CAS :CAY10722 is a SIRT3 inhibitor, affecting metabolism and cancer cell survival; varying impacts on esophageal and breast cancer.Formule :C21H14Cl2N2O2Couleur et forme :SolidMasse moléculaire :397.25KDM5A-IN-1
CAS :KDM5A-IN-1 is a pan-histidine lysine demethylase 5 KDM5 inhibitor that inhibits KDM5A, KDM5B, and KDM5C.Can be used in the study of cancer.Formule :C15H22N4O2Degré de pureté :>99.99%Couleur et forme :SolidMasse moléculaire :290.36Acefylline piperazine
CAS :Acefylline piperazine, a less toxic theophylline derivative, treats asthma and bronchitis by bronchodilation, stimulating respiration and CNS.Formule :C9H10N4O4·xC4H10N2Couleur et forme :SolidMasse moléculaire :562.54MAT2A-IN-7
CAS :MAT2A-IN-7 inhibits MAT2A in various cancers, especially MTAP-deficient cancer cells, with potential for research use.Formule :C17H13ClF3N3O2Couleur et forme :SolidMasse moléculaire :383.75SAR156497
CAS :SAR156497: selective Aurora A/B/C inhibitor; IC50: 0.5 nM (A), 1 nM (B), 3 nM (C); good metabolic stability; anti-tumoral without genetic specificity.Formule :C27H24N4O4Couleur et forme :SolidMasse moléculaire :468.5SKF 91488 dihydrochloride
CAS :histamine N-methyltransferase inhibitorFormule :C7H19Cl2N3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :248.22ART-IN-1
CAS :ART-IN-1 (compound 7) is a selective inhibitor of PARP with IC 50 s of 19, 22, 2.4, >100, 1.1 μM for PARP2, TNKS2, PARP10, PARP14, PARP15, respectively [1].Formule :C14H13NO2SCouleur et forme :SolidMasse moléculaire :259.32M133
CAS :M133 is a selective histone deacetylase HDAC1 and HDAC2 inhibitor and potent antitumor agent.Formule :C23H24N4OS2Couleur et forme :SolidMasse moléculaire :436.59(2R/S)-6-PNG
CAS :(2R/S)-6-PNG (6-Prenylnaringenin) from hops is a natural histone deacetylase inhibitor that blocks T-type calcium channels reducing neurogenicity in mice.Formule :C20H20O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :340.37ARTD10/PARP10-IN-1
CAS :ARTD10/PARP10-IN-1 is a PARP inhibitor that inhibits ARTD8/PARP14 and has anticancer and antitumour activity for the study of prostate cancer.Formule :C12H12N2O4Degré de pureté :99.14%Couleur et forme :SolidMasse moléculaire :248.23HDAC6/8/BRPF1-IN-1
CAS :HDAC6/8/BRPF1-IN-1 is a cancer-research inhibitor for HDAC6, HDAC8, BRPF1 with IC50: 344-908 nM and Kd: 175.2 nM.Formule :C18H17N3O5SCouleur et forme :SolidMasse moléculaire :387.41TM6008
CAS :TM6008 is an inhibitor of prolyl hydroxylase that protects against cell death after hypoxia.Formule :C21H17N5O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :387.39GSK926
CAS :GSK926 is a selective, SAM-competitive, and cell-active EZH2 inhibitor.Formule :C29H35N7O2Couleur et forme :SolidMasse moléculaire :513.63YM-53601 free base
CAS :YM-53601 free base is an inhibitor of squalene synthetase which suppresses lipogenic biosynthesis and lipid secretion in rodents.Formule :C21H21FN2ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :336.4Lorpucitinib
CAS :Lorpucitinib (JNJ-64251330) is a JAK kinase inhibitor used in the study of inflammatory and gastrointestinal diseases.Formule :C22H28N6O2Degré de pureté :99.72%Couleur et forme :SolidMasse moléculaire :408.5GW-841819X
CAS :GW841819X: (+)-JQ1 analogue, BET bromodomain inhibitor, active in vivo against various cancers.Formule :C25H21N5O2Couleur et forme :SolidMasse moléculaire :423.47KDM5B-IN-3
CAS :KDM5B-IN-3 inhibits KDM5B/JARID1B with IC50 of 9.32 μM, useful in gastric cancer studies.Formule :C19H25ClN4O2Couleur et forme :SolidMasse moléculaire :376.88SC-9
CAS :SC-9 is a protein kinase C activator.Formule :C22H24ClNO2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :401.95BRD4 Inhibitor-26
BRD4 Inhibitor-26: blocks BRD4 (BD1 and BD2) with IC50 of 0.82 μM & 1.94 μM; used in ovarian cancer research.Formule :C29H27N5O6SCouleur et forme :SolidMasse moléculaire :573.62(R)-UT-155
CAS :(R)-UT-155 is a selective androgen receptor degrader (SARD) ligand.Formule :C20H15F4N3O2Couleur et forme :SolidMasse moléculaire :405.35PDAT
CAS :PDAT is a noncompetitive Indolethylamine N-methyltransferase inhibitor.Formule :C15H23N3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :245.36CCT077791
CAS :CCT077791 is a potent inhibitor of p300 and PCAF histone acetyltransferase activity for cancer research.Formule :C9H5ClN2O3SDegré de pureté :98.60%Couleur et forme :SolidMasse moléculaire :256.67HOI-07
CAS :HOI-07 is a specific Aurora B inhibitor.Formule :C19H13NO4Couleur et forme :SolidMasse moléculaire :319.31Jaspamycin
CAS :Jaspamycin (7-CN-7-C-Ino) does not bind with purified human PKARIα.Formule :C12H12N4O5Couleur et forme :SolidMasse moléculaire :292.25Peficitinib hydrobromide
CAS :Peficitinib hydrobromide is used in the treatment of Psoriasis and Rheumatoid Arthritis.Formule :C18H23BrN4O2Couleur et forme :SolidMasse moléculaire :407.312Furamidine dihydrochloride
CAS :Furamidine dihydrochloride is a cell-permeable, selective PRMT1 inhibitor that also binds AT-rich DNA. It blocks proliferation in leukemia cell lines.Formule :C18H18Cl2N4ODegré de pureté :98.16%Couleur et forme :SolidMasse moléculaire :377.27Piribedil Maleate
CAS :Piribedil Maleate is a direct agonist of dopamine that acts by showing selectivity for the D3 subtype.Formule :C20H22N4O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :414.41AC430
CAS :AC430, a specific JAK2 inhibitor for cancer and autoimmune therapy, excels in preclinical trials with low doses. Developed by Ambit.Formule :C19H16FN5OCouleur et forme :SolidMasse moléculaire :349.36JNJ-9350
CAS :JNJ-9350: SMOX inhibitor (IC50 0.01 μM), PAO inhibitor (IC50 0.79 μM), for cancer research.Formule :C25H22N6OCouleur et forme :SolidMasse moléculaire :422.48GNE-272
CAS :GNE-272 is a selective inhibitor of CBP/EP300 (IC50: 0.02, 0.03, and 13 μM for CBP, EP300, and BRD4, respectively) and a selective in vivo probe for CBP/EP300.Formule :C22H25FN6O2Couleur et forme :SolidMasse moléculaire :424.47TP-238
CAS :"TP-238: Potent CECR2/BPTF dual probe; IC50: 30 nM/350 nM. Inhibits BRD9 (pIC50: 5.9); minimal activity on 338 other kinases."Formule :C22H30N6O3SCouleur et forme :SolidMasse moléculaire :458.58CL67
CAS :CL67 is a hypoxia-inducible factor pathway inhibitor. It acts by binding to a G-quadruplex higher-order structure in the HIF promoter sequence in vitro.Formule :C38H42N10O2Couleur et forme :SolidMasse moléculaire :670.81BAY-6035-R-isomer
CAS :BAY-6035 is an inhibitor of the methylation of MEKK2 peptide.Formule :C22H28N4O3Couleur et forme :SolidMasse moléculaire :396.48BRD4-BD1-IN-1
CAS :BRD4-BD1-IN-1 (Compound 9a) is a BRD4-BD1 inhibitor(IC50= 38.20 μM).Formule :C16H15BrN4O4Couleur et forme :SolidMasse moléculaire :407.22TFMB-(S)-2-HG
CAS :TFMB-(S)-2-HG (TFMB S 2 HG) is a highly effective inhibitor of TET2, the 5'-methylcytosine hydroxylase.Formule :C13H11F3O4Degré de pureté :98.07%Couleur et forme :SolidMasse moléculaire :288.22Ref: TM-T24871
2mg34,00€1mL*10mM (DMSO)49,00€5mg50,00€10mg79,00€25mg146,00€50mg227,00€100mg339,00€500mg713,00€CBHA
CAS :m-Carboxycinnamic bishydroxamide: HDAC inhibitor, ID50 = 10 nM (HDAC1), 70 nM (HDAC3), induces apoptosis and tumor growth suppression.Formule :C10H10N2O4Couleur et forme :SolidMasse moléculaire :222.25WKS
CAS :5WKS, or ZINC97756584, is a G9a inhibitor targeting H3K9me2 for gene silencing research in autoimmune diseases and tumors.Formule :C24H36ClN5O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :462.03PRMT5-IN-C17
CAS :PRMT5-IN-C17 is a novel potent, selective, and cell active protein arginine methyltransferase 5 (PRMT5) inhibitor.Formule :C18H17N3O4SCouleur et forme :SolidMasse moléculaire :371.41SGC6870
CAS :SGC6870 is a novel potent, selective, and cell-active inhibitor of PRMT6 with IC50 of 77 ± 6 nM, being selective over all other PRMTs and 23 methyltransferases.Formule :C23H21BrN2O2SCouleur et forme :SolidMasse moléculaire :469.39ABT-472
CAS :ABT-472 is a novel PARP inhibitorFormule :C20H28N4O5Couleur et forme :SolidMasse moléculaire :404.46JAK-IN-11
CAS :JAK-IN-11 (R-348) is a potent and selective inhibitor of JAK, has the potential for the skin disorders treatment.Formule :C23H22FN5O4SDegré de pureté :99.75%Couleur et forme :SolidMasse moléculaire :483.52CP-690550A
CAS :Cp-690550a is a novel JAK3 inhibitor, which is used to treat rheumatoid arthritis, graft rejection, psoriasis, and other immune-mediated diseases.Formule :C15H21N5O2Couleur et forme :SolidMasse moléculaire :303.36CREBBP-IN-9
CAS :CREBBP-IN-9, a CREBBP inhibitor, acts on the bromodomain of the protein.Formule :C16H15N5O2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :341.39SDR-04
CAS :SDR-04 inhibits BRD4-BD1 with high affinity, suppressing MV4;11 cancer cell growth as a BET inhibitor.Formule :C19H16N4O2Couleur et forme :SolidMasse moléculaire :332.36PARP1-IN-11
CAS :PARP1-IN-11 is a potent PARP1 inhibitor (IC50=0.082 μM), also reducing PARP3, TNKS1, and TNKS2 activity.Formule :C16H12N2O4Couleur et forme :SolidMasse moléculaire :296.28OHM1
CAS :OHM1, an analog of HIF1α CTAD, effectively inhibits the interaction between HIF1α CTAD and p300/CBP by targeting the CH1 domain with a binding affinity of 0.53Formule :C24H42N6O5Couleur et forme :SolidMasse moléculaire :494.63Pulrodemstat Methylbenzenesulfonate
CAS :LSD1-IN-7 Methylbenzenesulfonate is a potent and orally active inhibitor of lysine specific demethylase-1 (LSD1) with anticancer activity.Formule :C31H31F2N5O5SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :623.67AJH-836
CAS :AJH-836 is a compound that activates Munc13-1 and PKC ε/α, demonstrating a dissociation constant (Kd) of 4.5 nM for PKCα, and facilitates the translocation ofFormule :C22H38O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :382.53SIRT2-IN-9
CAS :SIRT2-IN-9: selective SIRT2 inhibitor; IC50=1.3μM; halts MCF-7 cell growth; for cancer study.Formule :C21H22N6OS2Degré de pureté :97.6%Couleur et forme :SolidMasse moléculaire :438.57ARTD10/PARP10-IN-2
CAS :ARTD10/PARP10-IN-2: A potent, non-selective PARP inhibitor, IC50: ARTD10/PARP10 (2.0μM), ARTD1/PARP1 (9.7μM).Formule :C12H13N3O3Couleur et forme :SolidMasse moléculaire :247.25OTS186935
CAS :OTS186935 is a inhibitor of protein methyltransferase SUV39H2(IC50 of 6.49 nM).Formule :C25H26ClN5O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :463.96JS1310
CAS :JS1310 is a selective PRMT7 inhibitor (IC50: 5 μM against human PRMT7). JS1310 has shown anti-cancer effects on different cancer cells.Formule :C23H22FN5O3Couleur et forme :SolidMasse moléculaire :435.45MIV-6
CAS :MIV-6 is an inhibitor of the menin-mixed lineage leukemia interaction.Formule :C27H35N3OCouleur et forme :SolidMasse moléculaire :417.59CEP-8983
CAS :CEP-8983 is a PARP inhibitor potentially for the treatment of solid tumours.Formule :C18H14N2O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :306.32Rucaparib camsylate
CAS :Rucaparib camsylate, a PARP-1, -2, -3 inhibitor (Ki=1.4 nM for PARP-1) & H6PD blocker, may treat resistant prostate cancer.Formule :C19H18FN3O·xC10H16O4SCouleur et forme :SolidY08284
CAS :Y08284: selective CBP bromodomain inhibitor, IC50: 4.21 nM, oral. Halts prostate cancer cell growth; anti-tumor.Formule :C26H25FN4O4Couleur et forme :SolidMasse moléculaire :476.5KDM2B-IN-3
CAS :KDM2B-IN-3, from patent WO2016112284A1 as compound 183c, potently inhibits histone demethylase KDM2B, with cancer research potential.Formule :C25H30N2O2Couleur et forme :SolidMasse moléculaire :390.52CeMMEC2
CAS :CeMMEC2, a novel inhibitor of BRD4, binds both the first and the second bromodomain of BRD4.Formule :C14H19N5Couleur et forme :SolidMasse moléculaire :257.33CM-579
CAS :CM-579 is a dual inhibitor of G9a and DNMT( IC50:16 nM, 32 nM for G9a and DNMT). It has potent in vitro cellular activity in a wide range of cancer cells.Formule :C29H40N4O3Degré de pureté :99.23%Couleur et forme :SolidMasse moléculaire :492.65Ref: TM-T10840L
1mg52,00€5mg90,00€1mL*10mM (DMSO)117,00€10mg131,00€25mg207,00€50mg303,00€100mg447,00€M-110
CAS :M-110 selectively targets PIM kinases, best at PIM-3 (IC50=47nM), and inhibits prostate cancer cell growth (IC50=0.6-0.9μM).Formule :C22H28ClN5O3Degré de pureté :99.55%Couleur et forme :SolidMasse moléculaire :445.94Y08175
CAS :Y08175, a CBP Bromodomain inhibitor, IC50: 37 nM (AlphaScreen), 178.15 nM (HTRF). Useful in prostate cancer research.Formule :C23H19FN4O5Couleur et forme :SolidMasse moléculaire :450.42HDAC-IN-28
CAS :HDAC-IN-28 is a novel inhibitor of HDAC that significantly inhibits tumour growth and metastasis.Formule :C23H26N4O4SCouleur et forme :SolidMasse moléculaire :454.54SMYD2-IN-1
CAS :SMYD2-IN-1 is an inhibitor of SMYD2 (IC50 of 4.45 nM).Formule :C25H25Cl2F2N7O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :564.41PIM1-IN-6
CAS :PIM1-IN-6 (5h) inhibits PIM-1 (IC50: 0.60 μM) and is cytotoxic to HCT-116 (IC50: 1.51 μM) and MCF-7 cells (IC50: 15.2 μM).Formule :C21H18N6O4Couleur et forme :SolidMasse moléculaire :418.41J1075
CAS :J1075 is an histone deacetylase 8 (HDAC8) inhibitor.Formule :C9H6ClNO2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :227.67Dot1L-IN-2
CAS :Dot1l-in-2 is an effective, selective and oral bioutilization inhibitor of histone methyltransferase Dot1L, with IC50 and Ki of 0.4 nM and 0.08 nM, respectivelyFormule :C27H24N8ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :476.53ML753286
CAS :ML753286 has high permeability and low to medium clearance in rodent and human liver S9 fractions.Formule :C20H25N3O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :355.43PKN1/2-IN-1
CAS :PKN1/2-IN-1 is a potent and selective PKN2 inhibitor, membrane permeability and anticancer.Protein kinase N proteins (PKN) are effectors of Rho GTPases.Formule :C14H15N3ODegré de pureté :99.72%Couleur et forme :SolidMasse moléculaire :241.29Ref: TM-T60339
2mg137,00€5mg222,00€1mL*10mM (DMSO)245,00€10mg356,00€25mg708,00€50mg1.063,00€100mg1.674,00€KU-0058684
CAS :KU-0058684 is a potent PARP and DNA-PK inhibitors.Formule :C19H14FN3O3Couleur et forme :SolidMasse moléculaire :351.33H8-A5
CAS :H8-A5, a HDAC8 inhibitor, shows antiproliferation activity in MDA-MB-231 cancer cells.Formule :C14H9F3N2O2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :326.29CBB1003
CAS :CBB1003 is a new inhibitor of histone demethylase LSD1 (IC50: 10.54 μM).Formule :C25H31N9O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :521.57CYP51/HDAC-IN-1
CAS :Orally active CYP51/HDAC-IN-1 dual inhibitor targets virulence factors and resistance genes; effective against Candidiasis and Cryptococcal meningitis.Formule :C30H40F2N6O4Couleur et forme :SolidMasse moléculaire :586.67HDAC6-IN-15
HDAC6-IN-15: selective HDAC6 inhibitor, IC50 of 38.2 nM, for cancer and neurodegenerative research.Formule :C25H28FFeN3O2Couleur et forme :SolidMasse moléculaire :477.35SIRT5 inhibitor 6
CAS :SIRT5 inhibitor 6 is Sirtuin 5 inhibitor for sepsis-associated acute kidney injury (AKI) modulates protein succinylation and pro-inflammatory cytokine release.Formule :C21H28N6O4SDegré de pureté :99.84%Couleur et forme :SolidMasse moléculaire :460.55OUL245
CAS :OUL245: A selective PARP2 inhibitor (IC50=44nM), also inhibits other PARPs/TNKS (IC50=2.9-8.8μM).Formule :C8H5N3OSCouleur et forme :SolidMasse moléculaire :191.21HDAC-IN-58
CAS :HDAC-IN-58, a selective HDAC6 inhibitor, exhibits potent inhibitory activity with an IC50 of 2.06 nM, rendering it suitable for research into chronicFormule :C16H13ClF2N4O3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :414.81Arazine
CAS :Arazine, a cell-permeable G protein modulator, is an isoprenylcysteine methyltransferase substrate.Formule :C20H33NO3SDegré de pureté :90%Couleur et forme :SolidMasse moléculaire :367.55BET-IN-7
CAS :BET-IN-7 is a potent BET inhibitor with a Ki of 12.27 μM and Kd of 89.3 μM, useful in sepsis research.Formule :C18H12ClN3OSCouleur et forme :SolidMasse moléculaire :353.83Aurora kinase inhibitor-9
CAS :Aurora kinase inhibitor-9 (9d) targets AURKA/B with IC50: 0.093 μM for A and 0.09 μM for B, with wide anti-proliferative effects.Formule :C19H17Cl2N3O4SCouleur et forme :SolidMasse moléculaire :454.33HDAC3 Inhibitor
CAS :HDAC3 inhibitor: allosteric, Ki=0.16 nM, favors HDAC3 over HDAC1/2, targets specific leukemia cells, EC50=36.37-151.7 nM.Formule :C20H23N3O2Couleur et forme :SolidMasse moléculaire :337.42HDAC1/MAO-B-IN-1
CAS :HDAC1/MAO-B-IN-1 is a selective Alzheimer’s research inhibitor with IC50s: HDAC1 (21.4 nM) & MAO-B (99 nM); crosses the blood-brain barrier.Formule :C18H17ClN2O2Couleur et forme :SolidMasse moléculaire :328.79CK2/PIM1-IN-1
CAS :CK2/PIM1-IN-1 inhibits CK2 & PIM1 (IC50s: 3.787 & 4.327 μM), aimed for cancer research.Formule :C15H9NO4S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :331.37PARP11 inhibitor ITK7
CAS :ITK7 is a potent, selective PARP11 inhibitor with an IC50 of 14 nM, useful for cellular localization research.Formule :C17H14N4OSCouleur et forme :SolidMasse moléculaire :322.38HDAC-IN-41
CAS :HDAC-IN-41 is a selective class I HDAC inhibiting HDAC1, 2, & 3 with IC50: 0.62-1.46 µM; oral use; has NO-release.Formule :C20H22N4O6SCouleur et forme :SolidMasse moléculaire :446.48YF479
CAS :YF479 is an inhibitor of histone deacetylase that acts by inhibiting breast tumor growth, metastasis, and recurrence.Formule :C22H27BrN2O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :479.36BI-831266
CAS :BI-831266 is a potent and selective Aurora kinase B inhibitor.Formule :C27H38ClN7O2Couleur et forme :SolidMasse moléculaire :528.09JAK1-IN-4
CAS :JAK1-IN-4 selectively blocks JAK1 (IC50 = 85 nM) over JAK2/JAK3 and halts STAT3 phosphorylation in NCI-H 1975 cells (IC50 = 227 nM).Formule :C26H32FN9O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :521.59MC4343
MC4343, a potent dual inhibitor targeting both EZH2 and histone deacetylase, presents promising potential for cancer research applications.Formule :C36H41N5O4Couleur et forme :SolidMasse moléculaire :607.74HDAC6-IN-14
HDAC6-IN-14, an inhibitor of HDAC6 (HDAC), exhibits high selectivity with an IC50 value of 42 nM, demonstrating over 100-fold selectivity compared to HDAC1,Formule :C24H30FN3O4Couleur et forme :SolidMasse moléculaire :443.51BIX-01338 hydrate
CAS :BIX-01338 hydrate is an inhibitor of histone lysine methyltransferase.Formule :C32H26F3N3O7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :621.56HDAC8/BRPF1-IN-1
CAS :Compound 23a, dual HDAC8/BRPF1 inhibitor: IC50 HDAC8 = 443 nM, Kd BRPF1 = 67 nM; weak against HDAC1/6.Formule :C19H19N3O6SCouleur et forme :SolidMasse moléculaire :417.44J1038
CAS :J1038 is a novel Histone Deacetylase 8 (HDAC8) Inhibitor .Formule :C10H10N2O3SCouleur et forme :SolidMasse moléculaire :238.26BRD4 Inhibitor-25
BRD4 Inhibitor-25 blocks BRD4 (BD1: IC50 0.82 μM, BD2: 1.94 μM), induces cell death in ovarian cancer, used in cancer research.Formule :C29H27N5O6SCouleur et forme :SolidMasse moléculaire :573.62CTX-0124143
CAS :CTX-0124143 is a histone acetyltransferase inhibitor with an IC50 value of 1.0 μM for KAT6A.CTX-0124143 can be used to study cellular senescence.Formule :C17H13FN2O3SDegré de pureté :98.24%Couleur et forme :SolidMasse moléculaire :344.36Exifone
CAS :Exifone (NSC-680919) is a mixed, nonessential activator of HDAC1 that is capable of binding to both free and substrate-bound enzyme, resulting in an increasedFormule :C13H10O7Degré de pureté :99.77% - 99.95%Couleur et forme :Yellow SolidMasse moléculaire :278.21CAY10685
CAS :CAY10685, a CPTH2 analog with an alkyne for click reactions, inhibits NAT10 to study cancer-related chromatin changes.Formule :C17H16ClN3SDegré de pureté :99.61%Couleur et forme :SolidMasse moléculaire :329.85SPV106
CAS :SPV106 is a ligand of lysine acetyltransferases (KATs).Formule :C22H40O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :368.55JAK-IN-18
CAS :"JAK-IN-18: potent JAK inhibitor for eye, skin, respiratory disease research (WO2018204238A1, comp 1)."Formule :C27H28F2N6O3Couleur et forme :SolidMasse moléculaire :522.55JAK-IN-21
CAS :JAK-IN-21 is a selective and potent JAK inhibitor that inhibits JAK1, JAK2, J2V617F and TYK2 with IC50 values of 1.73, 2.04, 109 and 62.9 nM, respectively.Formule :C19H16N8ODegré de pureté :99.87%Couleur et forme :SolidMasse moléculaire :372.38DNMT3A-IN-1
CAS :DNMT3A-IN-1 is a potent, selective DNMT3A inhibitor with KI 9.16-18.85 μM (AdoMet) and 11.37-23.34 μM (poly dI-dC).Formule :C30H38N6O4Couleur et forme :SolidMasse moléculaire :546.66ZYJ-25e
CAS :ZYJ-25e is an oral histone deacetylase inhibitor (HDACi) with potent antitumor activities.Formule :C30H40N4O8Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :584.66AChE/HDAC-IN-1
CAS :COX-2-IN-23 (A10) inhibits AChE & HDAC (IC50s: 0.12 & 0.23 nM), has antioxidant/metal-binding traits, and is used in Alzheimer's research.Formule :C26H27ClN4O3Couleur et forme :SolidMasse moléculaire :478.97Sirt2-IN-6
CAS :Sirt2-IN-6 is a potent and selective inhibitor of SIRT2 (IC50: 0.815 μM) and can be used to study cancer.Formule :C26H26N6O3SCouleur et forme :SolidMasse moléculaire :502.59MS453
CAS :MS453 is a potent and selective SETD8 inhibitor with an IC50 value of 804 nM.Formule :C20H27N5O3Couleur et forme :SolidMasse moléculaire :385.46TYK2-IN-11
CAS :TYK2-IN-11 (5B) selectively inhibits TYK2 (IC50: 0.016 nM) and JAK1 (IC50: 0.31 nM), aiding autoimmune and inflammatory disease research.Formule :C18H17N5O3SCouleur et forme :SolidMasse moléculaire :383.42INCB054329 Racemate
CAS :INCB054329 Racemate is an inhibitor of BET protein.Formule :C19H16N4O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :348.36PIM-1 Inhibitor 2
CAS :PIM-1 Inhibitor 2 (PIM1-IN-2) is a potent Pim-1 inhibitor with potential anti-cancer activity, used in cancer research.Formule :C17H11ClN4ODegré de pureté :98.81%Couleur et forme :SolidMasse moléculaire :322.75LSD1-IN-6
CAS :LSD1-IN-6, a potent LSD1 inhibitor (IC50: 123 nM), enhances H3K4me2 without altering LSD1 expression. Reversible.Formule :C15H13BrN2O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :349.18TK4b
CAS :TK4b, a JAK inhibitor, targets leukemia/lymphoid diseases, with IC50s: 18.42 nM (JAK3) & 19.40 nM (JAK2).Formule :C21H22N2O2Couleur et forme :SolidMasse moléculaire :334.411,2-Didecanoylglycerol
CAS :1,2-Didecanoylglycerol has functions as bioregulator of protein kinase C in human platelets.Formule :C23H44O5Couleur et forme :SolidMasse moléculaire :400.59Peficitinib hydrochloride
CAS :Peficitinib HCl (ASP015K) is an oral JAK inhibitor with IC50s: JAK1 (3.9 nM), JAK2 (5.0 nM), JAK3 (0.7 nM), Tyk2 (4.8 nM).Formule :C18H23ClN4O2Couleur et forme :SolidMasse moléculaire :362.86103D5R
CAS :103D5R selectively inhibits hif-1α, reducing its levels in hypoxia or with cobalt ions, dose- and time-dependently.Formule :C20H21N3O2Couleur et forme :SolidMasse moléculaire :335.4TM6089
CAS :TM6089 is an inhibitor of Prolyl Hydroxylase that stimulates HIF activity without iron chelation, induces angiogenesis, and protects organ against ischemia.Formule :C13H14N4O3SDegré de pureté :99.70%Couleur et forme :SolidMasse moléculaire :306.34Ref: TM-T17105
1mg50,00€5mg109,00€1mL*10mM (DMSO)116,00€10mg164,00€25mg285,00€50mg427,00€100mg623,00€200mg837,00€JAK-IN-20
CAS :JAK-IN-20: potent oral JAK1,2,3 inhibitor with IC50s 7, 5, 14 nM respectively, good pharmacokinetics, anti-inflammatory in vivo.Formule :C28H30FN7O2Couleur et forme :SolidMasse moléculaire :515.58JAK3i
CAS :JAK3i selectively inhibits JAK3 kinase, targeting the second, vital wave of STAT5 phosphorylation for T cell growth.Formule :C18H15FN4O3Degré de pureté :98.61% - 99.81%Couleur et forme :SolidMasse moléculaire :354.34CPUY074020
CAS :CPUY074020 is a potent and orally bioavailable inhibitor of histone methyltransferase G9a (IC50: 2.18 μM) with anti-proliferative activity.Formule :C25H28N4O2Degré de pureté :98.64%Couleur et forme :SolidMasse moléculaire :416.52Ref: TM-T10882
1mg71,00€5mg147,00€1mL*10mM (DMSO)159,00€10mg205,00€25mg319,00€50mg450,00€100mg587,00€200mg803,00€CARM1-IN-1
CAS :CARM1-IN-1 (CARM1-IN-7G) is a selective inhibitor of CARM1 with IC50 of 8.6 μM. CARM1-IN-1 shows weak activity against PRMT1 and SET7 with IC50 > 600 μM.Formule :C26H21Br2NO3Degré de pureté :98.24%Couleur et forme :SolidMasse moléculaire :555.26Ref: TM-T10682L
1mg34,00€5mg84,00€1mL*10mM (DMSO)92,00€10mg120,00€25mg236,00€50mg385,00€100mg600,00€200mg837,00€CEP-9722
CAS :CEP-9722 is a PARP-1 and PARP-2 inhibitor with anticancer activity and is used in the study of ovarian cancer.Formule :C24H26N4O3Degré de pureté :98.38% - 98.56%Couleur et forme :SolidMasse moléculaire :418.49β-NF-JQ1
CAS :β-NF-JQ1 is a PROTAC that recruits aryl hydrocarbon receptor E3 (AhR E3) ligase to target proteins.Formule :C45H42ClN5O6SDegré de pureté :97.58% - 99.15%Couleur et forme :SolidMasse moléculaire :816.36HDAC6 degrader 9c
CAS :HDAC6 degrader 9c is a small molecule histone deacetylase 6 (HDAC6) degrader that can be used to study cancer or other diseases.Formule :C37H45N9O10Degré de pureté :>99.99%Couleur et forme :SolidMasse moléculaire :775.81NSC668394
CAS :NSC668394 is an ezrin phosphorylation inhibitor.NSC668394 has antitumor activity and increases ezrin cleavage.NSC668394 can be used to study tumor metastasis.Formule :C17H12Br2N2O3Degré de pureté :99.29% - 99.29%Couleur et forme :SolidMasse moléculaire :452.1Givinostat hydrochloride
CAS :Givinostat HCl (ITF2357 HCl) inhibits HDAC1/3 (IC50: 198/157 nM) with anti-inflammatory, anti-angiogenic, and antineoplastic properties.Formule :C24H28ClN3O4Degré de pureté :99.39%Couleur et forme :SolidMasse moléculaire :457.95Ref: TM-T6279L
1mg35,00€5mg75,00€1mL*10mM (DMSO)77,00€10mg120,00€25mg240,00€50mg416,00€100mg663,00€200mg888,00€Flosequinan
CAS :Flosequinan is an arteriovenous vasodilator, which can effectively treat acute heart failure.Formule :C11H10FNO2SDegré de pureté :99.95%Couleur et forme :SolidMasse moléculaire :239.27Ref: TM-T31805
1mg175,00€1mL*10mM (DMSO)351,00€5mg394,00€10mg582,00€25mg888,00€50mg1.243,00€100mg1.674,00€500mg3.348,00€ACY-957
CAS :ACY-957: Oral HDAC1/2 inhibitor (IC50: HDAC1=7nM, HDAC2=18nM, HDAC3=1300nM); inactive on HDAC4/5/6/7/8/9.Formule :C24H23N5OSDegré de pureté :99.79%Couleur et forme :SolidMasse moléculaire :429.54Ref: TM-T10245
1mg90,00€2mg136,00€5mg230,00€1mL*10mM (DMSO)251,00€10mg281,00€25mg432,00€50mg612,00€100mg802,00€JAK1-IN-8
CAS :JAK1-IN-8, a specific inhibitor of Janus kinase 1 (JAK1, IC50<500 nM).
Formule :C22H23FN4O3SDegré de pureté :98.4%Couleur et forme :SolidMasse moléculaire :442.51PU139
CAS :PU139 is a novel inhibitor of histone acetyltransferase (HAT).Formule :C12H7FN2OSDegré de pureté :99.96%Couleur et forme :SolidMasse moléculaire :246.26CD532
CAS :CD532: Potent Aurora A inhibitor, IC50=45 nM, blocks kinase activity, degrades MYCN, interacts with AURKA, studies cancer.Formule :C26H25F3N8ODegré de pureté :99.99%Couleur et forme :SolidMasse moléculaire :522.52ACY-1083
CAS :ACY-1083 is a selective and brain-penetrating HDAC6 inhibitor (IC50: 3 nM) and effectively reverses chemotherapy-induced peripheral neuropathy.Formule :C17H18F2N4O2Degré de pureté :99.19% - 99.43%Couleur et forme :SolidMasse moléculaire :348.35Ref: TM-T10244
1mg144,00€5mg295,00€1mL*10mM (DMSO)326,00€10mg504,00€25mg795,00€50mg1.108,00€100mg1.494,00€500mg2.997,00€SK-575
CAS :SK-575 is a potent PARP1-degrading agent effective against BRCA1/2 mutant cancers, even at low doses, and enhances tumor inhibition in mice.Formule :C47H53FN8O8Degré de pureté :99.39%Couleur et forme :SolidMasse moléculaire :876.97ZEN-3862
CAS :ZEN-3862, a BET inhibitor, blocks BRD4(BD1) at 0.16 μM & BRD4(BD2) at 0.13 μM; usable in PROTACs for BRD4 degradation.Formule :C19H17FN2O3Degré de pureté :97.1%Couleur et forme :SolidMasse moléculaire :340.35MS0124
CAS :MS0124 is a potent and selective G9A-like protein (GLP) inhibitor with IC50 values of 13±4 nM and 440±63 nM, respectively.
Formule :C20H29N5O3Degré de pureté :98.97%Couleur et forme :SolidMasse moléculaire :387.48TGP-377/421
CAS :TGP-377/421 (Targapre-miR-377/421) is a potent miR-377 and miR-421 dual inhibitor that inhibits miR-377 and miR-421 by binding to their functional sites.Formule :C20H16N6Degré de pureté :97.02%Couleur et forme :SolidMasse moléculaire :340.38Ref: TM-T61085
1mg63,00€5mg137,00€1mL*10mM (DMSO)150,00€10mg215,00€25mg430,00€50mg695,00€100mg973,00€500mg1.945,00€ZEN-2759
CAS :ZEN-2759 is a potent BET small molecule inhibitor of BRD4(BD1), BRD4(BD2) and BRD4(BD1BD2).Formule :C17H16N2O2Degré de pureté :99.36%Couleur et forme :SolidMasse moléculaire :280.32GSK-690
CAS :GSK-690 is a potent, reversible and selective inhibitors of Lysine Specific Demethylase 1.Formule :C24H23N3ODegré de pureté :98.65%Couleur et forme :SolidMasse moléculaire :369.46TNG908
CAS :TNG908, a brain-penetrant PRMT5 inhibitor, is 15x more selective for MTAP mutant vs WT lines, useful in cancer studies.Formule :C21H23N5O2SDegré de pureté :98.08% - 98.24%Couleur et forme :SolidMasse moléculaire :409.51Ref: TM-T73494
1mg66,00€5mg145,00€1mL*10mM (DMSO)158,00€10mg224,00€25mg358,00€50mg512,00€100mg707,00€PF-249
CAS :PF-249 (PF-06685249) is a β1-selective AMPK with an EC50 of 12 nM for AMPK α1β1γ1 and can be used in studies about diabetic nephropathy.Formule :C17H16ClN3O3Degré de pureté :97.01%Couleur et forme :SolidMasse moléculaire :345.78Ref: TM-T24626
1mg46,00€5mg92,00€1mL*10mM (DMSO)100,00€10mg147,00€25mg236,00€50mg344,00€100mg482,00€200mg662,00€DCPLA-ME
CAS :DCPLA-ME (2-[(2-Pentylcyclopropyl)methyl]cyclopropaneoctanoic acid methyl ester) is the methyl ester form of DCPLA and can be used to treat neurodegenerativeFormule :C21H38O2Degré de pureté :99.80%Couleur et forme :SolidMasse moléculaire :322.53Ref: TM-T10980
1mg62,00€5mg126,00€1mL*10mM (DMSO)138,00€10mg172,00€25mg350,00€50mg572,00€100mg772,00€200mg1.054,00€GRK6-IN-1
CAS :GRK6-IN-1 (compound 18) is a potent GRK6 blocker, with an IC50 of 120 nM, showing promise for multiple myeloma research.Formule :C22H23ClN6O2Degré de pureté :99.37%Couleur et forme :SolidMasse moléculaire :438.91Ref: TM-T62518
1mg54,00€5mg114,00€1mL*10mM (DMSO)126,00€10mg178,00€25mg409,00€50mg708,00€100mg1.153,00€Izencitinib
CAS :Izencitinib (JNJ-8398) is a JAK inhibitor with potential anti-inflammatory activity for the study of ulcerative colitis and Crohn;s disease.Formule :C22H26N8Degré de pureté :99.82%Couleur et forme :SolidMasse moléculaire :402.50Ref: TM-T35898
1mg84,00€5mg177,00€1mL*10mM (DMSO)195,00€10mg281,00€25mg567,00€50mg888,00€100mg1.431,00€200mg1.963,00€DC-BPi-03
CAS :DC-BPi-03 is a potent BPTF-BRD inhibitor with an IC 50 of 698.3 nM and a K d of 2.81 μM .Formule :C14H14N4O2SDegré de pureté :98.96%Couleur et forme :SolidMasse moléculaire :302.35CMP-5
CAS :CMP-5 is a PRMT5 inhibitor with antiviral activity, inhibits PRMT5 methyltransferase activity, and can be used in the study of SARS virus infection.Formule :C21H21N3Degré de pureté :98.68%Couleur et forme :SolidMasse moléculaire :315.41Ref: TM-T10850
1mg44,00€5mg92,00€1mL*10mM (DMSO)101,00€10mg137,00€25mg225,00€50mg334,00€100mg494,00€500mg1.054,00€
