Chromatine/Épigénétique
Les inhibiteurs de la chromatine/épigénétique sont des composés qui modulent la structure et la fonction de la chromatine ou interfèrent avec les modifications épigénétiques, telles que la méthylation de l'ADN et la modification des histones. Ces inhibiteurs sont des outils essentiels pour étudier la régulation de l'expression génique et le rôle de l'épigénétique dans des maladies telles que le cancer, les troubles neurologiques et les anomalies du développement. En ciblant les processus épigénétiques, ces inhibiteurs peuvent modifier les schémas d'expression génique et offrir de nouvelles perspectives thérapeutiques. Chez CymitQuimica, nous offrons une large sélection d'inhibiteurs de la chromatine/épigénétique de haute qualité pour soutenir vos recherches en biologie moléculaire, génétique et épigénétique.
Sous-catégories appartenant à la catégorie "Chromatine/Épigénétique"
2235 produits trouvés pour "Chromatine/Épigénétique"
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AZD-1897
CAS :<p>AZD-1897 is a highly efficient ATP-competitive pan-PIM inhibitor with anti-cancer and anti-leukemia activity, used in multiple myeloma research.</p>Formule :C18H23N3O3SDegré de pureté :99.49%Couleur et forme :SolidMasse moléculaire :361.46PNZ5
CAS :<p>PNZ5, an isoxazole-based pan-BET inhibitor, demonstrates potent activity and high selectivity comparable to the established (+)-JQ1, exhibiting a dissociation</p>Formule :C20H18N2O2Degré de pureté :99.51% - 99.61%Couleur et forme :SolidMasse moléculaire :318.37KBH-A42
CAS :<p>KBH-A42 is an inhibitor of histone deacetylase.</p>Formule :C17H22N2O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :302.37JAK3/BTK-IN-1
CAS :<p>JAK3/ BTk-in-1 is a dual JAK3/BTK inhibitor that specifically targets and inhibits Janus kinase 3 (JAK3) and Bruton's tyrosine kinase (BTK), two important</p>Formule :C25H28N8ODegré de pureté :97.89%Couleur et forme :SolidMasse moléculaire :456.54DS-437
CAS :<p>DS-437 is a dual PRMT5/7 inhibitor (IC50s: 6 μM). DS-437 also inhibits DNMT3A and DNMT3B (IC50s: 52 and 62 μM). DS-437 inhibits the methylation of FOXP3.</p>Formule :C15H23N7O4SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :397.45JAK-IN-10
CAS :<p>JAK-IN-10 is a JAK inhibitor. JAK-IN-10 can be used for the research of dry eye disorders.</p>Formule :C20H18FN5O3SDegré de pureté :99.53%Couleur et forme :SolidMasse moléculaire :427.45(2R/S)-6-PNG
CAS :<p>(2R/S)-6-PNG (6-Prenylnaringenin) from hops is a natural histone deacetylase inhibitor that blocks T-type calcium channels reducing neurogenicity in mice.</p>Formule :C20H20O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :340.37SW155246
CAS :<p>SW155246 is a potent and selective inhibitor of DNMT1 (DNA methyltransferase 1; IC50 of 1.2 μM).</p>Formule :C16H11ClN2O5SDegré de pureté :98.99%Couleur et forme :SolidMasse moléculaire :378.79SIRT5 inhibitor 5
CAS :<p>SIRT5 inhibitor 5 is a selective and substrate-competitive SIRT5 inhibitor, which does not occupy the NAD+ binding pocket,cancer and metabolism-related disease.</p>Formule :C21H14ClN3O3SDegré de pureté :99.33%Couleur et forme :SolidMasse moléculaire :423.87EPZ032597
CAS :<p>EPZ032597 is a novel selective inhibitor of SMYD2 with an IC50 of 16 nM. EPZ032597 has anticancer activity and prevent and treat pancreatic cancer</p>Formule :C20H23N7ODegré de pureté :99.70%Couleur et forme :SolidMasse moléculaire :377.44KP-302
CAS :<p>KP-302 is a selective PAD inhibitor, reversing physical disability in multiple sclerosis (MS) mice and clearing T-cell infiltration in the brain.</p>Formule :C20H23N5O2Degré de pureté :99.77%Couleur et forme :SolidMasse moléculaire :365.43JAK-IN-28
CAS :<p>JAK-IN-28 (Compound 111) is a Janus kinase (JAK) inhibitor potentially applicable in the research of cancer and inflammatory diseases [1].</p>Formule :C20H18ClN7ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :407.86Valemetostat tosylate
CAS :<p>Valemetostat tosylate is a dual inhibitor of EZH1/2 and used in the research of relapsed/refractory peripheral T-cell lymphoma.</p>Formule :C33H42ClN3O7SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :660.22BET-IN-7
CAS :<p>BET-IN-7 is a potent BET inhibitor with a Ki of 12.27 μM and Kd of 89.3 μM, useful in sepsis research.</p>Formule :C18H12ClN3OSCouleur et forme :SolidMasse moléculaire :353.83Furamidine
CAS :<p>Furamidine is a PRMT1-selective, cell-permeable inhibitor (IC50: 9.4μM), also targeting TDP-1, and is an antiparasitic bisbenzamidine derivative.</p>Formule :C18H16N4ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :304.35GSK360A
CAS :<p>GSK360A is a novel prolyl hydroxylase (PHD) domain-containing enzyme inhibitor.</p>Formule :C17H17FN2O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :348.33Ilorasertib hydrochloride
CAS :<p>Ilorasertib hydrochloride (ABT-348 hydrochloride) is an ATP-competitive multitargeted kinase inhibitor, which inhibits Aurora C, Aurora B, and Aurora A (IC50s:</p>Formule :C25H22ClFN6O2SDegré de pureté :98.45%Couleur et forme :SolidMasse moléculaire :525JAK-IN-14
CAS :<p>JAK-IN-14 (compound 16) is a specific JAK1 inhibitor. It prevents JAK1 phosphorylation by binding to the active site of JAK in immune, inflammation and cancer.</p>Formule :C19H15FN4ODegré de pureté :98.27%Couleur et forme :SolidMasse moléculaire :334.35Aurora kinase inhibitor-10
CAS :<p>Aurora kinase inhibitor-10 is an orally active Aurora B inhibitor (IC50: 8 nM) that exhibits antitumour effects.</p>Formule :C21H19F5N6O4SCouleur et forme :SolidMasse moléculaire :546.47MT477
CAS :<p>MT477 inhibits PKC-α, impairs Ras/ERK1/2 phosphorylation, induces apoptosis, and reduces proliferation in various cancer cells.</p>Formule :C31H30N2O12S3Couleur et forme :SolidMasse moléculaire :718.77Rucaparib camsylate
CAS :<p>Rucaparib camsylate, a PARP-1, -2, -3 inhibitor (Ki=1.4 nM for PARP-1) & H6PD blocker, may treat resistant prostate cancer.</p>Formule :C19H18FN3O·xC10H16O4SCouleur et forme :SolidHIF-PHD-IN-2
CAS :<p>HIF-PHD-IN-2 (compound 25) is a highly effective PHD inhibitor, displaying IC50 values below 100 nM for PHD1, PHD2, and PHD3 [1].</p>Formule :C17H15N5O3SCouleur et forme :SolidMasse moléculaire :369.4dWIZ-1
CAS :<p>dWIZ-1 ((rac)-dWIZ-1) is a potent WIZ molecular gel degrader tha induction of haemoglobin fetalis (HbF) in erythroblasts, sickle cell disease (SCD).</p>Formule :C22H29N3O4Degré de pureté :92.87% - 92.87%Couleur et forme :SolidMasse moléculaire :399.48Y08284
CAS :<p>Y08284: selective CBP bromodomain inhibitor, IC50: 4.21 nM, oral. Halts prostate cancer cell growth; anti-tumor.</p>Formule :C26H25FN4O4Couleur et forme :SolidMasse moléculaire :476.5HIF-1/2α-IN-2
CAS :<p>HIF-1/2α-IN-2 is a potent inhibitor of HIF-1/2α, which effectively reduces the levels of HIF-1/2α.</p>Formule :C16H11FN4O2SCouleur et forme :SolidMasse moléculaire :342.35Tetrahydrouridine
CAS :<p>Tetrahydrouridine (NSC-112907; THU) is a multidrug resistance modulator.</p>Formule :C9H16N2O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :248.23Bizine
CAS :<p>Bizine, a Phenelzine analogue, selectively inhibits LSD1 (Ki=59 nM), modulates histone methylation in cancer, and may have neuroprotective uses.</p>Formule :C18H23N3OCouleur et forme :SolidMasse moléculaire :297.39Thi-DPPY
CAS :<p>Thi-DPPY: Potent JAK3/BTK inhibitor (IC50: 1.38/62.4 nM), anti-proliferative, anti-inflammatory, potential in IPF research.</p>Formule :C28H28ClN5O4SCouleur et forme :SolidMasse moléculaire :566.07HDAC3-IN-T247
CAS :<p>HDAC3-IN-T247 (HDAC3 inhibitor T247) is a histone deacetylase 3 (HDAC3) inhibitor with antiviral activity that inhibits the proliferation of cancer cells.</p>Formule :C21H19N5OSDegré de pureté :98.11% - 98.94%Couleur et forme :SolidMasse moléculaire :389.47SIRT1-IN-2
CAS :<p>SIRT1-IN-2 (compound 3h) is a potent and selective inhibitor of SIRT1 (silent information regulator 1) with an IC 50 of 1.6 μM [1].</p>Formule :C13H15ClN2OCouleur et forme :SolidMasse moléculaire :250.72IDO1 and HDAC1 Inhibitor
CAS :<p>IDO1 and HDAC1 Inhibitor is a dual IDO1 and HDAC1 inhibitor (IC50s: 69.0 nM and 66.5 nM).</p>Formule :C25H22BrFN8O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :597.4HDAC-IN-49
<p>HDAC-IN-49: potent, broad HDAC inhibitor; IC50s: 10-1880 nM for HDAC1-6; strong anti-leukemic, low toxicity to healthy cells.</p>Formule :C26H27FN4O4Couleur et forme :SolidMasse moléculaire :478.52CYP51/HDAC-IN-1
CAS :<p>Orally active CYP51/HDAC-IN-1 dual inhibitor targets virulence factors and resistance genes; effective against Candidiasis and Cryptococcal meningitis.</p>Formule :C30H40F2N6O4Couleur et forme :SolidMasse moléculaire :586.67TFMB-(S)-2-HG
CAS :<p>TFMB-(S)-2-HG (TFMB S 2 HG) is a highly effective inhibitor of TET2, the 5'-methylcytosine hydroxylase.</p>Formule :C13H11F3O4Degré de pureté :98.07%Couleur et forme :SolidMasse moléculaire :288.22Sirt1/2-IN-1
CAS :<p>Sirt1/2-IN-1 inhibits SIRT1 (IC50: 1.81 μg/mL) and SIRT2 (2.10 μg/mL), less on SIRT3 (20.5 μg/mL), with anticancer properties.</p>Formule :C22H13ClN2OS2Couleur et forme :SolidMasse moléculaire :420.93HDAC6-IN-15
<p>HDAC6-IN-15: selective HDAC6 inhibitor, IC50 of 38.2 nM, for cancer and neurodegenerative research.</p>Formule :C25H28FFeN3O2Couleur et forme :SolidMasse moléculaire :477.35M133
CAS :<p>M133 is a selective histone deacetylase HDAC1 and HDAC2 inhibitor and potent antitumor agent.</p>Formule :C23H24N4OS2Couleur et forme :SolidMasse moléculaire :436.59CBHA
CAS :<p>m-Carboxycinnamic bishydroxamide: HDAC inhibitor, ID50 = 10 nM (HDAC1), 70 nM (HDAC3), induces apoptosis and tumor growth suppression.</p>Formule :C10H10N2O4Couleur et forme :SolidMasse moléculaire :222.2Peficitinib hydrobromide
CAS :<p>Peficitinib hydrobromide is used in the treatment of Psoriasis and Rheumatoid Arthritis.</p>Formule :C18H23BrN4O2Couleur et forme :SolidMasse moléculaire :407.312PIM-1 Inhibitor 2
CAS :<p>PIM-1 Inhibitor 2 (PIM1-IN-2) is a potent Pim-1 inhibitor with potential anti-cancer activity, used in cancer research.</p>Formule :C17H11ClN4ODegré de pureté :98.81%Couleur et forme :SolidMasse moléculaire :322.75MI-2-2
CAS :<p>MI-2-2 is an inhibitor of bivalent protein-protein interaction between menin and MLL with an IC50 of 46 nM. MI-2-2 binds to menin with Kd of 22 nM.</p>Formule :C17H20F3N5S2Degré de pureté :99.65%Couleur et forme :SolidMasse moléculaire :415.5OUL245
CAS :<p>OUL245: A selective PARP2 inhibitor (IC50=44nM), also inhibits other PARPs/TNKS (IC50=2.9-8.8μM).</p>Formule :C8H5N3OSCouleur et forme :SolidMasse moléculaire :191.21YM-53601
CAS :<p>YM-53601 is an SQS inhibitor that inhibits adipogenic biosynthesis and lipid secretion in rodents.YM-53601 is a cholesterol-lowering agent that inhibits FDFT1.</p>Formule :C21H22ClFN2ODegré de pureté :99.65%Couleur et forme :SolidMasse moléculaire :372.86IACS-9571
CAS :<p>IACS-9571 is a selective and potent inhibitor of TRIM24 and BRPF1, (IC50: 8 nM for TRIM24; Kds: 31 nM and 14 nM for TRIM24 and BRPF1).</p>Formule :C32H42N4O8SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :642.76Tyk2-IN-5
CAS :<p>Tyk2-IN-5 is a selective and orally active inhibitor of Tyk2 JH2 (Ki: 0.086 nM for Tyk2 JH2; IC50: 25 nM for IFNα).</p>Formule :C21H19FN8O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :434.43CPI703
CAS :<p>CPI703 is a novel potent and specific CBP/EP300 bromodomain inhibitor.</p>Formule :C17H22N4ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :298.38JAK3/BTK-IN-2
CAS :<p>JAK3/ BTk-in-2 is a potent JAK3/BTK inhibitor.</p>Formule :C25H32N8O2Degré de pureté :99.64% - 99.87%Couleur et forme :SolidMasse moléculaire :476.57Bromodomain IN-1
CAS :<p>Bromodomain IN-1 is an inhibitor of Bromodomain.</p>Formule :C22H23ClN4O3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :458.962′-Deoxy-5-nitrocytidine
CAS :<p>2′-Deoxy-5-nitrocytidine is a DNA Methyltransferase inhibitor that can be used for cancer research[1].</p>Formule :C9H12N4O6Couleur et forme :SolidMasse moléculaire :272.216-Methyl-5-azacytidine
CAS :<p>6-Methyl-5-azacytidine is a potent DNMT inhibitor.</p>Formule :C9H14N4O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :258.23SB-284851-BT
CAS :<p>SB-284851-BT: BRD4/p38α/BRDT inhibitor; IC50: BRD4-BD1 1.7µM, BRDT 18µM, BRD4 3.7µM; Kd p38α 0.47nM; reduces IL-8, affects c-Myc/NF-κB.</p>Formule :C26H26FN5OCouleur et forme :SolidMasse moléculaire :443.52BET-BAY 002 (S enantiomer)
CAS :<p>The S-enantiomer of BET-BAY 002, referred to as BET-BAY 002 S enantiomer, is a potent inhibitor of BET (Bromodomain and Extra-Terminal motif proteins).</p>Formule :C22H18ClN5ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :403.86PKC-IN-4
CAS :<p>PKC-IN-4 (compound 7l) is a highly potent and orally active inhibitor of atypical protein kinase C (aPKC), exhibiting an IC 50 value of 0.52 μM.</p>Formule :C21H25N5SCouleur et forme :SolidMasse moléculaire :379.52CD161
CAS :<p>CD161: powerful, selective oral BET inhibitor; IC50: 28.2 nM (BRD4 BD1), 7.2 nM (BRD4 BD2); strong anticancer properties.</p>Formule :C26H21N5O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :435.48YF479
CAS :<p>YF479 is an inhibitor of histone deacetylase that acts by inhibiting breast tumor growth, metastasis, and recurrence.</p>Formule :C22H27BrN2O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :479.36TC-E 5001
CAS :<p>dual tankyrase (TNKS) inhibitor</p>Formule :C20H19N5O3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :409.46DC-CPin7
CAS :<p>DC-CPin7, a powerful inhibitor of the bromodomain of CREB-binding protein (CBP), exhibits an IC50 value of 2.5 μM [1].</p>Formule :C19H22N2O5Couleur et forme :SolidMasse moléculaire :358.39OICR-0547
CAS :<p>OICR-0547 is an inactive derivative of OICR-9429 and is commonly used as a negative control for OICR-9429.</p>Formule :C28H29F3N4O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :542.55HIF-1α inhibitor-1
CAS :<p>HIF-1α inhibitor-1 is a HIF-1 alpha inhibitor.</p>Formule :C15H11N3O4Couleur et forme :SolidMasse moléculaire :297.27Cercosporamide
CAS :<p>Cercosporamide is a ATP-competitive Pkc1 kinase inhibitor (IC50 <50 nM; Ki <7 nM). It also is a unique Mnk inhibitor.</p>Formule :C16H13NO7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :331.28Bisindolylmaleimide II
CAS :<p>protein kinase C (PKC) inhibitor</p>Formule :C27H26N4O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :438.52LSD1-IN-12
CAS :<p>LSD1-IN-12 (compound 2) is an effective inhibitor of LSD1, demonstrating inhibitory Ki values of 1.1 μM (LSD1), 61 μM (LSD2), 2.3 μM (MAO-A), and 3.5 μM (MAO-B</p>Formule :C16H16N2OCouleur et forme :SolidMasse moléculaire :252.31OM-137
CAS :<p>OM137 inhibits Aurora kinases, impedes cell growth at high doses, and enhances low-dose paclitaxel effects.</p>Formule :C13H14N4O3SCouleur et forme :SolidMasse moléculaire :306.34SRTCX1002
CAS :<p>SRTCX1002 is a SIRT1 Activator Suppressing Inflammatory Responses through Promotion of p65 Deacetylation and NF-κB Activity inhibitor.</p>Formule :C21H19N5O2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :405.47AMPK activator 6
CAS :<p>AMPK activator 6 stimulates AMPK, lowers lipids in cells, and reduces serum TC, LDL-C, and TG. Useful for NAFLD and metabolic research.</p>Formule :C25H28O5Couleur et forme :SolidMasse moléculaire :408.49ZLD1039
CAS :<p>ZLD1039, an oral EZH2 inhibitor, shows strong PRC2 inhibition at low nanomolar IC50s, and halts breast cancer growth and spread.</p>Formule :C36H48N6O3Degré de pureté :99.5%Couleur et forme :SolidMasse moléculaire :612.8PU141
CAS :<p>PU141 is a novel inhibitor of histone acetyltransferase (HAT).</p>Formule :C14H9F3N2OSDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :310.29CHIC35
CAS :<p>CHIC-35 is a selective deacetylase SIRT1 inhibitor.</p>Formule :C14H15ClN2OCouleur et forme :SolidMasse moléculaire :262.73OTS186935 trihydrochloride
CAS :<p>OTS186935 trihydrochloride is a protein methyltransferase inhibitor of SUV39H2(IC50 of 6.49 nM).</p>Formule :C25H29Cl4N5O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :573.34GNA002
CAS :<p>GNA002 is a highly potent, specific, and covalent EZH2 (Enhancer of zeste homolog 2) inhibitor (IC50: 1.1 μM).</p>Formule :C42H55NO8Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :701.89ET-JQ1-OH
CAS :<p>ET-JQ1-OH is an allele-specific BET inhibitor.</p>Formule :C21H21ClN4O2SCouleur et forme :SolidMasse moléculaire :428.93SMTIN-T140
CAS :<p>SMTIN-T140: strong TRAP1 inhibitor, IC50=1.646μM, anticancer; disrupts mitochondria, boosts ROS, activates AMPK, shrinks PC3 tumors, no in vivo toxicity.</p>Formule :C36H34BrClFN5OPDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :718.02F5446
CAS :<p>F5446 is a selective small molecule SUV39H1 methyltransferase inhibitor, promotes apoptosis in colorectal cancer cells by inhibiting the deposition of H3K9me3.</p>Formule :C26H17ClN2O8SDegré de pureté :98.56%Couleur et forme :SolidMasse moléculaire :552.94MicroRNA-21-IN-2
CAS :<p>MicroRNA-21-IN-2 is a potential miR-21 inhibitor with an AC50 value of 3.29 μM. MicroRNA-21-IN-2 can be used to study cancer.</p>Formule :C17H15N3O3SDegré de pureté :99.2%Couleur et forme :SolidMasse moléculaire :341.38CX-6258
CAS :<p>CX-6258 is an orally valid Pim 1/2/3 kinase(IC50=5 nM/25 nM/16 nM) inhibitor. It has good biological activity and kinase specificity.</p>Formule :C26H24ClN3O3Degré de pureté :97.46%Couleur et forme :SolidMasse moléculaire :461.94BAY1238097
CAS :<p>BAY1238097 is a BET inhibitor with anticancer activity and antiproliferative activity for the study of advanced refractory malignancies.</p>Formule :C25H33N5O3Degré de pureté :98.1% - 98.79%Couleur et forme :SolidMasse moléculaire :451.56EZH2-IN-3
CAS :<p>EZH2-IN-3 is an inhibitor of EZH2 and EZH1 with selective impact on diffuse large B cell lymphoma cell growth.</p>Formule :C27H28ClN5O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :490CSV0C018875
CAS :<p>CSV0C018875 is a quinoline-based EHMT2/G9a inhibitor with lower cytotoxicity than BIX-01294 [1].</p>Formule :C18H17ClN2OCouleur et forme :SolidMasse moléculaire :312.79SPV106
CAS :<p>SPV106 is a ligand of lysine acetyltransferases (KATs).</p>Formule :C22H40O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :368.55BIX-01338 hydrate
CAS :<p>BIX-01338 hydrate is an inhibitor of histone lysine methyltransferase.</p>Formule :C32H26F3N3O7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :621.56(2R,5S)-Ritlecitinib
CAS :<p>(2R,5S)-Ritlecitinib ((2R,5S)-PF-06651600) is a potent and selective inhibitor of JAK3 with IC 50 of 144.8 nM[1].</p>Formule :C15H19N5OCouleur et forme :SolidMasse moléculaire :285.34PI3K/Akt/CREB activator 1
CAS :<p>PI3K/Akt/CREB activator 1 (AE-18) is an iNOS inhibitor that can be used to study vascular dementia and Parkinson's.</p>Formule :C19H15F4NO3Couleur et forme :SolidMasse moléculaire :381.32Povorcitinib
CAS :<p>Povorcitinib is a highly potent and selective JAK1 inhibitor with significant potential for the investigation of cutaneous lupus erythematosus (CLE) and Lichen planus (LP).</p>Formule :C23H22F5N7OCouleur et forme :SolidMasse moléculaire :507.469JAK3-IN-1
CAS :<p>JAK3-IN-1 is an orally active, selective and potent JAK3 inhibitor for the study of immune system disorders.</p>Formule :C26H30ClN7O2Couleur et forme :SolidMasse moléculaire :508.02SRTCX1003
CAS :<p>SRTCX1003, a SIRT1 activator, suppresses inflammatory responses through promotion of p65 deacetylation and inhibition of NF-κB activity.</p>Formule :C23H23N5O3SCouleur et forme :SolidMasse moléculaire :449.53Aurora Kinases-IN-3
CAS :<p>Aurora Kinases-IN-3 is an oral AURKB inhibitor that disrupts its mitotic localization, not its H3 Ser10 phosphorylation.</p>Formule :C20H16F3N3O4Couleur et forme :SolidMasse moléculaire :419.35PBRM1-BD2-IN-6
CAS :<p>PBRM1-BD2-IN-6: potent PBRM1 inhibitor with 0.22 µM IC50, anti-cancer research potential.</p>Formule :C16H15ClN2OCouleur et forme :SolidMasse moléculaire :286.76CK2/PIM1-IN-1
CAS :<p>CK2/PIM1-IN-1 inhibits CK2 & PIM1 (IC50s: 3.787 & 4.327 μM), aimed for cancer research.</p>Formule :C15H9NO4S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :331.37HDAC3 Inhibitor
CAS :<p>HDAC3 inhibitor: allosteric, Ki=0.16 nM, favors HDAC3 over HDAC1/2, targets specific leukemia cells, EC50=36.37-151.7 nM.</p>Formule :C20H23N3O2Couleur et forme :SolidMasse moléculaire :337.42AMPK activator 8
CAS :<p>AMPK activator 8 targets rAMPK α1β1γ1/α2β1γ1/α1β2γ1 (EC50: 11/27/4 nM) for type 2 diabetes research.</p>Formule :C25H21ClN2O6Couleur et forme :SolidMasse moléculaire :480.9RET-IN-19
CAS :<p>RET-IN-19, a potent RET inhibitor, anticancer: IC50 6.8 nM (RET-wt), 13.51 nM (RET V804M); for NSCLC research.</p>Formule :C28H28N6O4SCouleur et forme :SolidMasse moléculaire :544.62KCN1
CAS :<p>KCN1: a synthetic sulfonamide, nanomolar HIF inhibitor with preclinical anti-glioma and anti-pancreatic cancer effects.</p>Formule :C26H27NO5SCouleur et forme :SolidMasse moléculaire :465.56SIRT2-IN-10
CAS :<p>SIRT2-IN-10 (Compound 12) is a potent inhibitor of SIRT2 (IC50: 1.3 μM), which can be used in the study of cancer and neurodegenerative diseases.</p>Formule :C28H21N5OSCouleur et forme :SolidMasse moléculaire :475.56SIRT5 inhibitor 4
CAS :<p>SIRT5 inhibitor 4 (compound 11) is a dose-dependent and selective SIRT5 (Sirtuin5) inhibitorand no inhibitory effect on SIRT1/2/3,anticancer.</p>Formule :C18H15N3O4SDegré de pureté :99.97%Couleur et forme :SolidMasse moléculaire :369.39KDM5-C49
CAS :<p>KDM5-C49 is a potent and selective inhibitor of KDM5, which regulates cell proliferation and stem cell self-renewal and differentiation.</p>Formule :C15H24N4O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :308.38Dot1L-IN-2
CAS :<p>Dot1l-in-2 is an effective, selective and oral bioutilization inhibitor of histone methyltransferase Dot1L, with IC50 and Ki of 0.4 nM and 0.08 nM, respectively</p>Formule :C27H24N8ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :476.53CMP-5 hydrochloride
CAS :<p>CMP-5 hydrochloride: potent, selective PRMT5 inhibitor; inactive against PRMT1/4/7; blocks S2Me-H4R3 on histones.</p>Formule :C21H22ClN3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :351.87UMB-136
CAS :<p>UMB-136 is a bromodomain BRD4 inhibitor that acts by significantly inducing HIV-1 reactivation.</p>Formule :C24H27N5O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :417.5BRM/BRG1 ATP Inhibitor-3
CAS :<p>BRM/BRG1 ATP Inhibitor-3 targets BRM/BRG1 (IC50: 10.4/19.3 nM) for cancer/BAF disorder research.</p>Formule :C26H25N5O2S2Couleur et forme :SolidMasse moléculaire :503.64OTS186935
CAS :<p>OTS186935 is a inhibitor of protein methyltransferase SUV39H2(IC50 of 6.49 nM).</p>Formule :C25H26ClN5O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :463.96Dimethyl-bisphenol A
CAS :<p>DMBPA inhibits HIF-1α, promotes its degradation by detaching Hsp90, and reduces Vegfa mRNA expression.</p>Formule :C17H20O2Couleur et forme :SolidMasse moléculaire :256.34TyK2-IN-2
CAS :<p>TyK2-IN-2 is a selective inhibitor of TYK2 (IC50s: 7 nM, 0.1 μM, and 0.05 μM for TYK2 JH2, IL-23, and IFNα).</p>Formule :C16H18N6ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :310.35SRI-42127
CAS :<p>SRI-42127 is a novel small molecule inhibitor of the RNA regulatory factor HuR that inhibits tumor growth and reduces neuropathic pain following nerve injury.</p>Formule :C19H20N6ODegré de pureté :99.66%Couleur et forme :SolidMasse moléculaire :348.4SIRT5 inhibitor 6
CAS :<p>SIRT5 inhibitor 6 is Sirtuin 5 inhibitor for sepsis-associated acute kidney injury (AKI) modulates protein succinylation and pro-inflammatory cytokine release.</p>Formule :C21H28N6O4SDegré de pureté :99.84%Couleur et forme :SolidMasse moléculaire :460.55CTX-0124143
CAS :<p>CTX-0124143 is a histone acetyltransferase inhibitor with an IC50 value of 1.0 μM for KAT6A.CTX-0124143 can be used to study cellular senescence.</p>Formule :C17H13FN2O3SDegré de pureté :99.16%Couleur et forme :SolidMasse moléculaire :344.36NSD3-IN-2
CAS :<p>NSD3-IN-2: Potent NSD3 inhibitor, IC50 17.97μM, halts NSCLC growth (H460, H1299, H1650) with anticancer effects.</p>Formule :C17H15N5OSCouleur et forme :SolidMasse moléculaire :337.4NSD3-IN-3
CAS :<p>"NSD3-IN-3, a potent anticancer agent, inhibits NSD3 (IC50: 1.86 μM) and hampers H460 lung cancer cell growth."</p>Formule :C15H17N5O2SCouleur et forme :SolidMasse moléculaire :331.39PRMT5-IN-C17
CAS :<p>PRMT5-IN-C17 is a novel potent, selective, and cell active protein arginine methyltransferase 5 (PRMT5) inhibitor.</p>Formule :C18H17N3O4SCouleur et forme :SolidMasse moléculaire :371.415WKS
CAS :<p>5WKS, or ZINC97756584, is a G9a inhibitor targeting H3K9me2 for gene silencing research in autoimmune diseases and tumors.</p>Formule :C24H36ClN5O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :462.03NC-III-49-1
CAS :<p>NC-III-49-1: potent BET inhibitor, binds BRD4/BRDT, inhibits cell growth, reduces c-Myc expression.</p>Formule :C44H50N4O11S2Couleur et forme :SoildMasse moléculaire :875.02CL67
CAS :<p>CL67 is a hypoxia-inducible factor pathway inhibitor. It acts by binding to a G-quadruplex higher-order structure in the HIF promoter sequence in vitro.</p>Formule :C38H42N10O2Couleur et forme :SolidMasse moléculaire :670.81HDAC-IN-44
CAS :<p>HDAC-IN-44 is an HDAC inhibitor (IC50: 61.2 nM) with strong anti-cancer effects.</p>Formule :C26H27BrN4O4Couleur et forme :SolidMasse moléculaire :539.42PDAT
CAS :<p>PDAT is a noncompetitive Indolethylamine N-methyltransferase inhibitor.</p>Formule :C15H23N3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :245.36TM6008
CAS :<p>TM6008 is an inhibitor of prolyl hydroxylase that protects against cell death after hypoxia.</p>Formule :C21H17N5O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :387.39BET bromodomain inhibitor 2
CAS :<p>BET bromodomain inhibitor 2 is a potent inhibitor of the BET-type bromodomain (IC50: 14.1 μM).</p>Formule :C23H30N2O5SCouleur et forme :SolidMasse moléculaire :446.56SKF 91488 dihydrochloride
CAS :<p>histamine N-methyltransferase inhibitor</p>Formule :C7H19Cl2N3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :248.22GDC-4379
CAS :<p>GDC-4379 is a JAK1 inhibitor that can be used to study asthma.</p>Formule :C21H18ClF2N7O3Couleur et forme :SolidMasse moléculaire :489.86Y08175
CAS :<p>Y08175, a CBP Bromodomain inhibitor, IC50: 37 nM (AlphaScreen), 178.15 nM (HTRF). Useful in prostate cancer research.</p>Formule :C23H19FN4O5Couleur et forme :SolidMasse moléculaire :450.42RSC-133
CAS :<p>promotes the reprogramming of human somatic cells to pluripotent stem cells</p>Formule :C18H15N3O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :305.33HDAC6-IN-10
CAS :<p>HDAC6-IN-10 is a potent HDAC6 inhibitor with 0.73 nM IC50, highly selective, and hinders multiple myeloma cell growth.</p>Formule :C21H20N4O4Couleur et forme :SolidMasse moléculaire :392.41MAT2A inhibitor 3
CAS :<p>MAT2A inhibitor 3 can be used in the cancer research.</p>Formule :C16H14ClN3OCouleur et forme :SolidMasse moléculaire :299.75MAT2A-IN-5
CAS :<p>MAT2A-IN-5 inhibits MAT2A in tumors, curbing growth in gastric, colon, liver, and pancreatic cancers.</p>Formule :C17H12ClF3N2OCouleur et forme :SolidMasse moléculaire :352.74SIRT6-IN-1
CAS :<p>SIRT6-IN-1, a novel SIRT6 inhibitor, reduces glycemia and improves oral glucose tolerance in unfed wild-type mice.</p>Formule :C19H14N4O5SCouleur et forme :SolidMasse moléculaire :410.4JAK3i
CAS :<p>JAK3i selectively inhibits JAK3 kinase, targeting the second, vital wave of STAT5 phosphorylation for T cell growth.</p>Formule :C18H15FN4O3Degré de pureté :98.61% - 99.81%Couleur et forme :SolidMasse moléculaire :354.34ABT-472
CAS :<p>ABT-472 is a novel PARP inhibitor</p>Formule :C20H28N4O5Couleur et forme :SolidMasse moléculaire :404.46INCB054329 Racemate
CAS :<p>INCB054329 Racemate is an inhibitor of BET protein.</p>Formule :C19H16N4O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :348.36EML741
CAS :<p>EML741 also inhibits DNMT1 (IC50, 3.1 μM), with no effect on DNMT3a or DNMT3b.</p>Formule :C31H49N5O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :523.75IHCH-3064
CAS :<p>IHCH-3064: dual-action cancer immunotherapy, A2AR affinity (Ki 2.2 nM), selective HDAC1 inhibitor (IC50 80.2 nM).</p>Formule :C25H21N9O2Couleur et forme :SolidMasse moléculaire :479.49HDAC6-IN-6
CAS :<p>HDAC6-IN-6: Potent HDAC6 blocker, BBB-permeable, IC50: 0.025μM; inhibits AChE, Aβ 1-42 aggregation; promotes neurite growth, low neurotoxicity.</p>Formule :C20H15N3O2Couleur et forme :SolidMasse moléculaire :329.35A2AAR/HDAC-IN-2
CAS :<p>A2AAR/HDAC-IN-2: potent dual A2AAR/HDAC inhib., Ki 10.3 nM, IC50 18.5 nM, anti-tumor potential.</p>Formule :C23H26N6O4Couleur et forme :SolidMasse moléculaire :450.49NSC 698600
CAS :<p>NSC 698600 is a potent inhibitor of PCAF(p300/CBP-associated factor) with IC 50 of 6.51 μM that shows good inhibition activity of cancer cell proliferation [1].</p>Formule :C14H12N2O2SCouleur et forme :SolidMasse moléculaire :272.32SPC-180002
CAS :<p>SPC-180002, a dual SIRT1/3 inhibitor, exhibits IC50 values of 1.13 and 5.41 μM for SIRT1 and SIRT3, respectively.</p>Formule :C18H23NO4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :317.38JAK-IN-18
CAS :<p>"JAK-IN-18: potent JAK inhibitor for eye, skin, respiratory disease research (WO2018204238A1, comp 1)."</p>Formule :C27H28F2N6O3Couleur et forme :SolidMasse moléculaire :522.55Setin-1
CAS :<p>Setin-1 is the most potent Set7 inhibitor that acts by inhibiting the KMTase G9a.</p>Formule :C29H21F3N2O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :486.48GSK 525768A
CAS :<p>GSK 525768A, the inactive enantiomer of GSK525762A, exhibits no activity towards BET.</p>Formule :C22H22ClN5O2Couleur et forme :SolidMasse moléculaire :423.9OXFBD03
CAS :<p>OXFBD03 is the bromodomain and extra terminal domain bromodomain family member BRD4(1) inhibitor.</p>Formule :C20H19NO4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :337.37LY 170198
CAS :<p>LY 170198 is a protein kinase C inhibitor.</p>Formule :C22H25N5O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :439.46HPCG
CAS :<p>HPCG is an inhibitor of HIF-1α prolyl hydroxylase.</p>Formule :C8H8N2O4Couleur et forme :SolidMasse moléculaire :196.16DHPCC-9
CAS :<p>DHPCC-9 is an inhibitor of Pim kinase.</p>Formule :C15H10N2OCouleur et forme :SolidMasse moléculaire :234.25DC_501
CAS :<p>DC_501 is a selective non-nucleoside DNA methyltransferase 1 inhibitor.</p>Formule :C25H23Cl2N3ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :452.38Sirtuin modulator 4
CAS :<p>Sirtuin modulator 4 inhibits SIRT1 (EC50: 51-100 μM), may extend cell life and prevent diseases like diabetes and cancer.</p>Formule :C18H10N2O2SCouleur et forme :SolidMasse moléculaire :318.35DCE_254
CAS :<p>DCE_254 is a novel EZH2 inhibitor, it also displays significant anti-proliferation activity against lymphoma cell lines.</p>Formule :C21H17N9OSDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :443.48Langkamide
CAS :<p>Langkamide is a HIF-2 inhibitor with EC₅₀ values of 14.0 uM.</p>Formule :C16H17NO5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :303.31I-BET151 dihydrochloride
CAS :<p>I-BET 151 dihydrochloride is a BET bromodomain inhibitor that prevents BET from recruiting to chromatin.</p>Formule :C23H23Cl2N5O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :488.37Vibsanin A
CAS :<p>Vibsanin A, an activator of protein kinase C (PKC) and an inhibitor of HSP90, demonstrates anti-proliferative effects on human cancer cell lines.</p>Formule :C25H38O4Couleur et forme :SolidMasse moléculaire :402.57BF1
CAS :<p>BF1 is an inhibitor of HAT (histone acetyltransferase) active both in vitro and in vivo.</p>Formule :C12H12ClN3SCouleur et forme :SolidMasse moléculaire :265.76Farnesylthiotriazole
CAS :<p>Farnesylthiotriazole is a persistent PKC activator agent.</p>Formule :C17H27N3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :305.48Tenovin-D3
CAS :<p>Tenovin-D3 is a sirtuin SirT2 inhibitor. It acts by increasing p21 (CDKN1A) expression in a p53-independent manner.</p>Formule :C22H27Cl3N4O3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :533.9ML399
CAS :<p>ML399 inhibits menin-MLL interaction, targeting MLL leukemia cells with selective, potent action.</p>Formule :C27H28FN3O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :445.53iBRD4-BD1
CAS :<p>iBRD4-BD1 inhibits BRD4 bromodomain selectively with 12 nM IC50, useful in inflammation and cancer research.</p>Formule :C29H30F3N5OCouleur et forme :SolidMasse moléculaire :521.58HIF-IN-33
CAS :<p>HIF-IN-33 is an inhibitor of HIF pathway.</p>Formule :C21H17F3N4O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :414.38CPI-905
CAS :<p>CPI-905 is a potent and selective EZH2 inhibitor with IC50 value of 39.5 nM.</p>Formule :C18H20N2O5Couleur et forme :SolidMasse moléculaire :344.36BET-BAY 002
CAS :<p>BET-BAY 002 is an effective BET bromodomain inhibitor demonstrating efficacy in vivo and in vitro against multiple myeloma and leukaemia models.</p>Formule :C22H18ClN5OCouleur et forme :SolidMasse moléculaire :403.86Fagaronine chloride
CAS :<p>Fagaronine chloride is a potent inhibitor of Topoisomerases I.</p>Formule :C21H20ClNO4Couleur et forme :SolidMasse moléculaire :385.84HDAC6-IN-5
CAS :<p>HDAC6-IN-5 (11b), potent HDAC6 blocker, crosses BBB, IC50: 0.025μM, hinders Aβ1-42/AChE aggregation, boosts neurites, low toxicity.</p>Formule :C20H14BrN3O2Couleur et forme :SolidMasse moléculaire :408.25Lobelane Hydrochloride
CAS :<p>Lobelane Hydrochloride is a vesicular monoamine transporter-2 (VMAT2) inhibitor.</p>Formule :C22H30ClNCouleur et forme :SolidMasse moléculaire :343.93TP-238
CAS :<p>"TP-238: Potent CECR2/BPTF dual probe; IC50: 30 nM/350 nM. Inhibits BRD9 (pIC50: 5.9); minimal activity on 338 other kinases."</p>Formule :C22H30N6O3SCouleur et forme :SolidMasse moléculaire :458.58CTPB
CAS :<p>CTPB is a potent p300 histone acetyltransferase (HAT) activator that can be used in the preparation of hair growth promoters and/or hair loss treatments.</p>Formule :C31H43ClF3NO2Degré de pureté :99.77%Couleur et forme :SolidMasse moléculaire :554.13SirReal-1
CAS :<p>SirReal-1 is an effective and selective inhibitor of Sirt2.</p>Formule :C18H18N4OS2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :370.49Prospasmine
CAS :<p>Prospasmine is an anticholinergic.</p>Formule :C17H28ClNO2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :313.87JAK3-IN-12
CAS :<p>JAK3-IN-12 (compound 15k) is a potent inhibitor of JAK3 (IC50: 9.5 nM) and can be used in the study of rheumatoid arthritis.</p>Formule :C19H19N5O4SCouleur et forme :SolidMasse moléculaire :413.45Hns 32
CAS :<p>Hns 32 possesses antiarrhythmic properties in dog and guinea pig hearts. It also has vasodilator action.</p>Formule :C24H29N3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :359.51p32 Inhibitor M36
CAS :<p>p32 inhibitor M36 is an inhibitor of p32 mitochondrial protein. It binds directly to p32 and inhibits the p32 association with LyP-1.</p>Formule :C23H28N8O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :448.52AMPK activator 1
CAS :<p>AMPK activator 1 is an AMPK activator(compound No.1-75, EC50: <0.1μM).</p>Formule :C32H33F3N4O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :578.62ST7710AA1
CAS :<p>ST7710AA1 inhibits PARP-1, effectively targets in vitro, and overcomes Pgp-associated multidrug resistance.</p>Formule :C20H22N4OCouleur et forme :SolidMasse moléculaire :334.41NCGC00247743
CAS :<p>NCGC00247743 is an inhibitor of histone lysine demethylase KDM4.</p>Formule :C24H29N3O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :391.51MI-3
CAS :<p>MI-3 (Menin-MLL Inhibitor) (Menin-MLL Inhibitor) is an effective inhibitor of Menin-MLL interaction (IC50: 648 nM).</p>Formule :C18H25N5S2Degré de pureté :98.66% - 99.61%Couleur et forme :SolidMasse moléculaire :375.55GPI-15427
CAS :<p>GPI-15427: a potent PARP-1 inhibitor, crosses the blood-brain barrier, boosts TMZ's effects on CNS tumors, and sensitizes cancer to radiotherapy.</p>Formule :C20H20N4O2Couleur et forme :SolidMasse moléculaire :348.4Binucleine 2
CAS :<p>Binucleine 2: Drosophila Aurora B kinase inhibitor (Ki=0.36μM), dose-dependent, minimal effect on human/X. laevis kinases, disrupts mitosis in fly cells.</p>Formule :C13H11ClFN5Couleur et forme :SolidMasse moléculaire :291.71GSK926
CAS :<p>GSK926 is a selective, SAM-competitive, and cell-active EZH2 inhibitor.</p>Formule :C29H35N7O2Couleur et forme :SolidMasse moléculaire :513.63CREBBP-IN-9
CAS :<p>CREBBP-IN-9, a CREBBP inhibitor, acts on the bromodomain of the protein.</p>Formule :C16H15N5O2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :341.39CPI-1612
CAS :<p>CPI-1612: Oral EP300/CBP HAT inhibitor, IC50 8.1 nM, has anticancer properties.</p>Formule :C27H26N6OCouleur et forme :SolidMasse moléculaire :450.53HDAC-IN-28
CAS :<p>HDAC-IN-28 is a novel inhibitor of HDAC that significantly inhibits tumour growth and metastasis.</p>Formule :C23H26N4O4SCouleur et forme :SolidMasse moléculaire :454.54SDR-04
CAS :<p>SDR-04 inhibits BRD4-BD1 with high affinity, suppressing MV4;11 cancer cell growth as a BET inhibitor.</p>Formule :C19H16N4O2Couleur et forme :SolidMasse moléculaire :332.36H8-A5
CAS :<p>H8-A5, a HDAC8 inhibitor, shows antiproliferation activity in MDA-MB-231 cancer cells.</p>Formule :C14H9F3N2O2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :326.29ZLD2218
CAS :<p>ZLD2218, a potent inhibitor of BRD4 with an IC50 value of 107 nM, has been demonstrated to mitigate kidney injury and fibrosis through extensive studies.</p>Formule :C22H18N4OCouleur et forme :SolidMasse moléculaire :354.4TK4g
CAS :<p>TK4g, a potent JAK inhibitor, has IC50s of 12.61 nM (JAK2) & 15.80 nM (JAK3); promising for lymphoid diseases & leukemia research.</p>Formule :C19H19N3O4SCouleur et forme :SolidMasse moléculaire :385.44BRD4 Inhibitor-19
CAS :<p>BRD4 inhibitors -19 are BET inhibitors that act on BRD4-BD1 (IC50: 55 nM) and can be used to study multiple myeloma.</p>Formule :C29H25N5O3Couleur et forme :SolidMasse moléculaire :491.54Arazine
CAS :<p>Arazine, a cell-permeable G protein modulator, is an isoprenylcysteine methyltransferase substrate.</p>Formule :C20H33NO3SDegré de pureté :90%Couleur et forme :SolidMasse moléculaire :367.55PARP1-IN-11
CAS :<p>PARP1-IN-11 is a potent PARP1 inhibitor (IC50=0.082 μM), also reducing PARP3, TNKS1, and TNKS2 activity.</p>Formule :C16H12N2O4Couleur et forme :SolidMasse moléculaire :296.28WD2000-012547
CAS :<p>WD2000-012547 is a selective inhibitor of poly(ADP-ribose)-polymerase (PARP-1) (pKi: 8.221).</p>Formule :C17H14N2ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :262.31NV03
CAS :<p>NV03 is a selective antagonist of the UHRF1-H3K9me3 interaction (Kd=2.4 μM) for cancer research. a ligand for E3 ligases in PROTAC synthesis.</p>Formule :C19H27N5O2SDegré de pureté :99.88%Couleur et forme :SolidMasse moléculaire :389.52MS453
CAS :<p>MS453 is a potent and selective SETD8 inhibitor with an IC50 value of 804 nM.</p>Formule :C20H27N5O3Couleur et forme :SolidMasse moléculaire :385.46NR-160
CAS :<p>NR-160 is a selective HDAC6 inhibitor (IC50=0.03μM), weaker on HDAC1-4,8, toxic to 7 cancer lines, boosts bortezomib and anthracycline effects.</p>Formule :C25H21F3N6O3Couleur et forme :SolidMasse moléculaire :510.47M122
CAS :<p>M122 is a selective histone deacetylase HDAC1 and HDAC2 inhibitor and potent antitumor agent.</p>Formule :C24H25N5OS2Couleur et forme :SolidMasse moléculaire :463.62UMB-32
CAS :<p>UMB-32: Potent, selective BRD4 inhibitor, Kd 550 nM, IC50 637 nM, also targets TAF1.</p>Formule :C21H23N5OCouleur et forme :SolidMasse moléculaire :361.44CTK7A
CAS :<p>CTK7A is a water-soluble inhibitor of p300. CTK7A inhibits tumor growth in xenografted mice.</p>Formule :C28H24N2NaO6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :507.498Bromodomain inhibitor-10
CAS :<p>Bromodomain inhibitor-10 (compound 128) suppresses BRD4-1/2 with Kd 15 nM/2.5 μM and curbs IL12p40 production.</p>Formule :C20H20N4O3Couleur et forme :SolidMasse moléculaire :364.4MAT2A inhibitor 1
CAS :<p>MAT2A inhibitor 1 is an inhibitor of methionine adenosyltransferase 2A (MATA2) (IC50 < l00 nM).</p>Formule :C31H22N6OSCouleur et forme :SolidMasse moléculaire :526.61FNDR-20123 free base
CAS :<p>FNDR-20123 is a safe, oral first-in-class anti-malarial HDAC inhibitor with low IC50s against Plasmodium and human HDACs.</p>Formule :C21H23N5O2Couleur et forme :SolidMasse moléculaire :377.44TAK-418
CAS :<p>TAK-418 is an orally active LSD1/KDM1A inhibitor with a 2.9 nM IC50, potential for autism therapy.</p>Formule :C17H25ClN2O2SDegré de pureté :99.69%Couleur et forme :SolidMasse moléculaire :356.91SB-429201
CAS :<p>SB-429201 is an effective, selective inhibitor of HDAC1.</p>Formule :C28H24N2O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :436.5CAY10669
CAS :<p>CAY10669 inhibits PCAF (IC50 = 662 μM), is twice as potent as anacardic acid, and reduces H4 acetylation in HepG2 cells at 30-60 μM.</p>Formule :C20H22O4Couleur et forme :SolidMasse moléculaire :326.39JNJ-7925476 free base
CAS :<p>JNJ-7925476 is an TRI antidepressant agent.</p>Formule :C20H19NDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :273.37PF-00956980
CAS :<p>PF-00956980: reversible JAK inhibitor, IC50: JAK1 (2.2μM), JAK2 (23.1μM), JAK3 (59.9μM), for lung/skin inflammation research.</p>Formule :C18H26N6OCouleur et forme :SolidMasse moléculaire :342.44UNC6212 (Kme2)
<p>UNC6212 (Kme2), a dimethyllysine (Kme2)-containing ligand, has a K D for CBX5 of 5.7 μM .</p>Formule :C39H53N7O11Couleur et forme :SolidMasse moléculaire :795.88BAY-598 R-isomer
CAS :<p>BAY-598 R-isomer, a SMYD2-selective inhibitor, is the R-enantiomer of BAY589, not targeting PAR1.</p>Formule :C22H20Cl2F2N6O3Couleur et forme :SolidMasse moléculaire :525.34J1075
CAS :<p>J1075 is an histone deacetylase 8 (HDAC8) inhibitor.</p>Formule :C9H6ClNO2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :227.67S-Aristeromycinylhomocysteine
CAS :<p>S-Aristeromycinylhomocysteine is an inhibitor of adenosylmethionine decarboxylase.</p>Formule :C15H22N6O4SCouleur et forme :SolidMasse moléculaire :382.44(R)-OR-S1
CAS :<p>(R)-OR-S1 is a SAM-competitive, highly selective, orally bioavailable dual inhibitor of EZH1/2.</p>Formule :C26H34BrN3O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :532.47
