Chromatine/Épigénétique
Les inhibiteurs de la chromatine/épigénétique sont des composés qui modulent la structure et la fonction de la chromatine ou interfèrent avec les modifications épigénétiques, telles que la méthylation de l'ADN et la modification des histones. Ces inhibiteurs sont des outils essentiels pour étudier la régulation de l'expression génique et le rôle de l'épigénétique dans des maladies telles que le cancer, les troubles neurologiques et les anomalies du développement. En ciblant les processus épigénétiques, ces inhibiteurs peuvent modifier les schémas d'expression génique et offrir de nouvelles perspectives thérapeutiques. Chez CymitQuimica, nous offrons une large sélection d'inhibiteurs de la chromatine/épigénétique de haute qualité pour soutenir vos recherches en biologie moléculaire, génétique et épigénétique.
Sous-catégories appartenant à la catégorie "Chromatine/Épigénétique"
2235 produits trouvés pour "Chromatine/Épigénétique"
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AS-85
CAS :<p>AS-85 is an ASH1L inhibitor with anti-leukemic activity that inhibits leukemic cell growth and increases cLogP.</p>Formule :C26H28F3N5O3S2Degré de pureté :98.96%Couleur et forme :SolidMasse moléculaire :579.66DTP3
CAS :<p>DTP3 is a selective MKK7/GADD45β inhibitor, which inhibits cancer-selective NF-κB survival pathway.</p>Formule :C26H35N7O5Couleur et forme :SolidMasse moléculaire :525.6TPOP146
CAS :<p>TPOP146 is a selective CBP/P300 benzoxazepine bromodomain inhibitor (Kd: 134 nM and 5.02 μM for CBP and BRD4).</p>Formule :C27H35N3O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :481.58PROTAC EZH2 Degrader-1
CAS :<p>PROTAC EZH2 Degrader-1 suppresses EZH2 methyltransferase activity with IC50 2.7 nM, serving as a potent tool in cancer research and EZH2 inhibition studies.</p>Formule :C54H67N7O8Couleur et forme :SolidMasse moléculaire :942.15GSK778
CAS :<p>GSK778 selectively inhibits BD1 bromodomains (BRD2, BRD3, BRD4, BRDT) and impedes cell growth, causing arrest and apoptosis.</p>Formule :C30H33N5O3Degré de pureté :98.42%Couleur et forme :SolidMasse moléculaire :511.61KDM4C-IN-1
CAS :<p>KDM4C-IN-1 is aKDM4C inhibitor withial anticancer activity.KDM4C-IN-1 inhibits the growth of HepG2 and A549 cells, and can be used for the study of leukaemia.</p>Formule :C15H14N4O3Degré de pureté :99.33%Couleur et forme :SolidMasse moléculaire :298.3(2R)-Octyl-α-hydroxyglutarate
CAS :<p>(2R)-Octyl-α-hydroxyglutarate ((2R)-Octyl-2-HG) is a D-isomer 2-Hydroxyglutarate modified form.</p>Formule :C13H24O5Couleur et forme :SolidMasse moléculaire :260.33SGC-iMLLT
CAS :<p>SGC-iMLLT is a potent and selective MLLT1/3-histone interactions inhibitor(IC50 = 0.26 μM),and is a first-in-class chemical probe displaying cellular target</p>Formule :C22H24N6ODegré de pureté :99.21%Couleur et forme :SolidMasse moléculaire :388.47Itacitinib adipate
CAS :<p>Itacitinib adipate: oral JAK1 inhibitor, tested in phase II myelofibrosis trial.</p>Formule :C32H33F4N9O5Couleur et forme :SolidMasse moléculaire :699.66TH1834
CAS :<p>TH1834 is a specific inhibitor of Tip60/KAT5 histone acetyltransferase. TH1834 induces apoptosis and DNA damage in MCF.</p>Formule :C33H40N6O3Degré de pureté :99.96%Couleur et forme :SolidMasse moléculaire :568.71GSK2879552
CAS :<p>GSK2879552: oral, irreversible LSD1 inhibitor with potential cancer-fighting properties.</p>Formule :C23H28N2O2Degré de pureté :99.22%Couleur et forme :SolidMasse moléculaire :364.48Boc-Lys(Ac)-AMC
CAS :<p>Boc-Lys(Ac)-AMC (Boc-L-Lys(Ac)-AMC) is a synthetic substrate coupled to an HDAC-specific fluorophore (Ex/Em = 355 nm/460 nm).</p>Formule :C23H31N3O6Degré de pureté :99.87%Couleur et forme :SolidMasse moléculaire :445.51AZ505 ditrifluoroacetate
CAS :<p>AZ505 ditrifluoroacetate is an effective and selective SMYD2 inhibitor (IC50: 0.12 μM).</p>Formule :C33H40Cl2F6N4O8Couleur et forme :SolidMasse moléculaire :805.59EHMT2-IN-1
CAS :<p>EHMT2-IN-1: potent EHMT inhibitor, for blood disorders/cancer research; IC50s <100 nM for EHMT1/2 peptides and cellular EHMT2.</p>Formule :C18H23N7OCouleur et forme :SolidMasse moléculaire :353.42JET-209
<p>JET-209 is a potent proteolysis-targeting chimera (PROTAC) that effectively degrades CBP/p300, exhibiting half-maximal degradation concentration (DC50) values</p>Formule :C46H47N9O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :821.92GSK-J2
CAS :<p>GSK-J2 is an inactive enantiomer of GSK-J1 that is lipophilic and serves as an inactive control for GSK-J21.</p>Formule :C22H23N5O2Degré de pureté :97.55%Couleur et forme :SolidMasse moléculaire :389.45Pim-1/2 kinase inhibitor 1
CAS :<p>Orally active Pim-1/2 inhibitor blocks kinase phosphorylation; used in prostate cancer research.</p>Formule :C11H9NO3SDegré de pureté :99.78%Couleur et forme :SolidMasse moléculaire :235.26GSK9311
CAS :<p>GSK9311 inhibits BRPF bromodomain (pIC50: 6.0 and 4.3 for BRPF1 and BRPF2, respectively).</p>Formule :C24H31N5O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :437.53N-Descyclopropanecarbaldehyde Olaparib
CAS :<p>N-Descyclopropanecarbaldehyde Olaparib is a CRBN ligand for dual EGFR/PARP PROTAC, suitable for F-18 radiolabeling and tumor imaging via PET.</p>Formule :C20H19FN4O2Couleur et forme :SolidMasse moléculaire :366.39INO-1001
CAS :<p>INO-1001: potent PARP inhibitor with antitumor properties, enhances radiosensitivity & radiation-induced cell death.</p>Formule :C23H25N3O4SCouleur et forme :SolidMasse moléculaire :439.53CHZ868
CAS :<p>CHZ868 is a type II JAK inhibitor with potential antitumor activity that reverses the persistence of type I JAK inhibitors and can be used to study leukemia.</p>Formule :C22H19F2N5O2Degré de pureté :99.38%Couleur et forme :SolidMasse moléculaire :423.42ADTL-SA1215
CAS :<p>ADTL-SA1215 is a SIRT3 activator with SIRT3 deacetylase activity for the study of triple negative breast cancer.</p>Formule :C26H29I2NO3Degré de pureté :99.23%Couleur et forme :SolidMasse moléculaire :657.32(±)-1,2-Diolein
CAS :<p>(±)-1,2-Diolein (1,2-Dioleoyl-rac-glycerol) (1,2-Dioleoyl-rac-glycerol) is a PKC activator. (±)-1,2-Diolein could increases myotubes Ca 2+ influx.</p>Formule :C39H72O5Couleur et forme :SolidMasse moléculaire :620.992'-Deoxy-2'-fluoro-β-D-arabinocytidine hydrochloride
CAS :<p>2'-Deoxy-2'-fluoro-beta-D-arabinocytidine HCl inhibits DNA methyltransferase with potential anti-tumor properties.</p>Formule :C9H13ClFN3O4Degré de pureté :99.69%Couleur et forme :SolidMasse moléculaire :281.67MS8511 hydrochloride
CAS :<p>MS8511 hydrochloride is a selective G9a/GLP inhibitor with IC50 values of 100 nM and 140 nM respectively, exhibiting covalent and irreversible characteristics.</p>Formule :C28H42ClN5O3Couleur et forme :SolidMasse moléculaire :532.12Fenbendazole-d3
CAS :<p>Fenbendazole-d3 is a deuterated compound of Fenbendazole. Fenbendazole has a CAS number of 43210-67-9. Fenbendazole is an antinematodal benzimidazole used in veterinary medicine.</p>Formule :C15H10D3N3O2SCouleur et forme :SolidMasse moléculaire :302.37(R)-GSK-3685032
CAS :<p>(R)-GSK-3685032 is a selective, reversible DNMT1 inhibitor, non-covalent, IC50: 0.036 μM; reduces DNA methylation, inhibits cancer growth.</p>Formule :C22H24N6OSCouleur et forme :SolidMasse moléculaire :420.54Atinvicitinib
CAS :<p>Atinvicitinib, a selective JAK1 inhibitor, blocks cytokine signaling, modulating itch, allergy, and inflammatory responses, immune and therapeutic studies.</p>Formule :C16H17FN6O3Degré de pureté :99.36%Couleur et forme :SolidMasse moléculaire :360.35CX-6258 hydrochloride hydrate
CAS :<p>CX-6258 hydrochloride hydrate is a potent and selective inhibitor of pan-Pim kinase that acts on Pim-1 (IC50: 5 nM), Pim-2 (IC50: 25 nM) and Pim-3 (IC50: 16 nM</p>Formule :C26H27Cl2N3O4Couleur et forme :SolidMasse moléculaire :516.42Ilunocitinib
CAS :<p>Ilunocitinib is a non-selective and orally active Janus kinase (JAK) inhibitor for pruritus and atopic dermatitis caused by atopic dermatitis in dogs.</p>Formule :C17H17N7O2SDegré de pureté :99.88%Couleur et forme :SolidMasse moléculaire :383.43O6BTG-octylglucoside
CAS :<p>O6BTG-octylglucoside is a potent O6-methylguanine-DNAmethyl-transferase (MGMT) inhibitor (IC50s: 10 nM and 32 nM in HeLa S3 cells and in vitro (cell extracts)).</p>Formule :C24H34BrN5O7SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :616.53BAY-850
CAS :<p>BAY-850 is ainhibitor of adenosine triphosphatase family protein 2 that inhibits ovarian cancer growth and metastasis in in vitro and in vivo models.</p>Formule :C38H44ClN5O3Degré de pureté :98% - 98%Couleur et forme :SolidMasse moléculaire :654.24DA-3003-1
CAS :<p>DA-3003-1 (NSC 663284) is a Cdc25 dual specificity phosphatase inhibitor with antitumor activity and inhibits Cdc25B2, Cdc25A, Cdc25B2, and Cdc25C.</p>Formule :C15H16ClN3O3Degré de pureté :99.27% - 99.79%Couleur et forme :SolidMasse moléculaire :321.761,4-DPCA ethyl ester
CAS :<p>1,4-DPCA ethyl ester is a form of 1,4-DPCA modified, which has potential anticancer activity based on growth inhibition assays with the mlh1 rad18 yeast strain.</p>Formule :C15H12N2O3Degré de pureté :99.54%Couleur et forme :SolidMasse moléculaire :268.27NSC 694621
CAS :<p>NSC 694621 is a PCAF inhibitor that forms a covalent bond with Cys574, irreversibly inhibiting its acetyltransferase activity, inhibit proliferation,anticancer.</p>Formule :C13H10N2O2SDegré de pureté :99.7%Couleur et forme :SolidMasse moléculaire :258.3Anti-PARP1 Antibody (8I163)
<p>Anti-PARP1 Antibody (8I163) is a Mouse antibody targeting PARP1. Anti-PARP1 Antibody (8I163) can be used in IHC-P.</p>Couleur et forme :Odour LiquidAnti-PARP Antibody (1W26)
<p>Anti-PARP Antibody (1W26) is a Mouse antibody targeting PARP. Anti-PARP Antibody (1W26) can be used in WB,IHC-P,IP.</p>Couleur et forme :Odour LiquidAnti-PARP1 Antibody (6I459)
<p>Anti-PARP1 Antibody (6I459) is an antibody targeting PARP1. Anti-PARP1 Antibody (6I459) can be used in ELISA, IHC.</p>Couleur et forme :Odour LiquidAnti-PARP1 Antibody (7A800)
<p>Anti-PARP1 Antibody (7A800) is an antibody targeting PARP1. Anti-PARP1 Antibody (7A800) can be used in ELISA, WB, IHC.</p>Couleur et forme :Odour LiquidAnti-PARP1 Antibody (9E313)
<p>Anti-PARP1 Antibody (9E313) is a Mouse antibody targeting PARP1. Anti-PARP1 Antibody (9E313) can be used in IHC-P.</p>Couleur et forme :Odour LiquidAnti-PARP1 Antibody (8S756)
<p>Anti-PARP1 Antibody (8S756) is an antibody targeting PARP1. Anti-PARP1 Antibody (8S756) can be used in ELISA, WB, IHC, IF, FCM.</p>Couleur et forme :Odour LiquidGintemetostat
CAS :<p>Gintemetostat (KTX-1001) is a potent NSD2 inhibitor (IC50=0.001-0.01μM) for treating NSD2-dysregulated cancers.</p>Formule :C25H26F4N8O2Couleur et forme :SolidMasse moléculaire :546.52PR5-LL-CM01
CAS :<p>PR5-LL-CM01 is a novel protein arginine methyltransferase 5 (PRMT5) inhibitor in colorectal and pancreatic cancers.</p>Formule :C23H27N7Couleur et forme :SolidMasse moléculaire :401.51PROTAC PARP1 degrader
CAS :<p>PROTAC PARP1 degrader suppresses MDA-MB-231 cells at 10 μM, IC50: 6.12 μM in 24h.</p>Formule :C58H63Cl2N11O10Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1145.1Ifidancitinib
CAS :<p>Ifidancitinib (ATI-50002) is a JAK kinase 1/3 inhibitor used to study autoimmune diseases.</p>Formule :C20H18FN5O3Degré de pureté :98.05%Couleur et forme :SolidMasse moléculaire :395.39I-BET567
CAS :<p>I-BET567: potent, oral pan-BET inhibitor; pIC50s: 6.9 (BRD4 BD1), 7.2 (BD2); effective in mouse cancer and inflammation models.</p>Formule :C17H18ClN5O2Degré de pureté :99.8%Couleur et forme :SolidMasse moléculaire :359.817-Chloro-4-(piperazin-1-yl)quinoline
CAS :<p>7-Cl-4-(piperazin-1-yl)quinolone: sirtuin inhibitor, serotonin uptake blocker, antimalarial (D10 IC50 1.18µM, K1 IC50 0.97µM).</p>Formule :C13H14ClN3Degré de pureté :99.52%Couleur et forme :Light Yellow SolidMasse moléculaire :247.72AMI-1 free acid
CAS :<p>AMI-1: Potent reversible PRMT inhibitor; IC50: 8.8 μM (hPRMT1), 3.0 μM (yeast-Hmt1p); blocks substrate binding.</p>Formule :C21H16N2O9S2Degré de pureté :97.8%Couleur et forme :SolidMasse moléculaire :504.49PCAF-IN-1
CAS :<p>PCAF-IN-1 is a highly selective PCAF inhibitor with potential anti-tumor, anti-inflammatory, and anti-heart disease effects.</p>Formule :C15H11ClN6Couleur et forme :SolidMasse moléculaire :310.74KDM4-IN-3
CAS :<p>KDM4-IN-3 is a KDM4 inhibitor that is cell-permeable and kills prostate cancer cells at low micromolar concentrations.</p>Formule :C17H14N4OCouleur et forme :SolidMasse moléculaire :290.32
