Chromatine/Épigénétique
Les inhibiteurs de la chromatine/épigénétique sont des composés qui modulent la structure et la fonction de la chromatine ou interfèrent avec les modifications épigénétiques, telles que la méthylation de l'ADN et la modification des histones. Ces inhibiteurs sont des outils essentiels pour étudier la régulation de l'expression génique et le rôle de l'épigénétique dans des maladies telles que le cancer, les troubles neurologiques et les anomalies du développement. En ciblant les processus épigénétiques, ces inhibiteurs peuvent modifier les schémas d'expression génique et offrir de nouvelles perspectives thérapeutiques. Chez CymitQuimica, nous offrons une large sélection d'inhibiteurs de la chromatine/épigénétique de haute qualité pour soutenir vos recherches en biologie moléculaire, génétique et épigénétique.
Sous-catégories appartenant à la catégorie "Chromatine/Épigénétique"
2613 produits trouvés pour "Chromatine/Épigénétique"
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ML324
CAS :ML324(IC50=920 nM) is a specific inhibitor of jumonji histone demethylase (JMJD2).Formule :C21H23N3O2Degré de pureté :98.22% - 98.57%Couleur et forme :SolidMasse moléculaire :349.43Ref: TM-T6593
2mg34,00€5mg49,00€10mg74,00€25mg122,00€50mg205,00€100mg334,00€200mg494,00€1mL*10mM (DMSO)79,00€PFI-2 hydrochloride
CAS :PFI-2 hydrochloride ((R)-PFI-2 hydrochloride) is a potent, highly selective, and cell-active inhibitor of the methyltransferase activity of SETD7 (IC50: 2 nM),Formule :C23H26ClF4N3O3SDegré de pureté :99.31% - 99.91%Couleur et forme :SolidMasse moléculaire :535.98Ref: TM-T4583
1mg38,00€2mg49,00€5mg80,00€10mg111,00€25mg200,00€50mg358,00€100mg523,00€500mg1.108,00€1mL*10mM (DMSO)122,00€C646
CAS :C646, a histone acetyltransferase inhibitor, inhibits p300 (Ki: 400 nM, in a cell-free assay).Formule :C24H19N3O6Degré de pureté :98% - 99.21%Couleur et forme :SolidMasse moléculaire :445.42Ref: TM-T2452
2mg46,00€5mg65,00€10mg92,00€25mg185,00€50mg360,00€100mg532,00€500mg1.144,00€1mL*10mM (DMSO)65,00€4-amino-1,8-Naphthalimide
CAS :4-amino-1,8-Naphthalimide (4-ANI) is a PARP inhibitor with IC50 of 180 nMFormule :C12H8N2O2Degré de pureté :95.13%Couleur et forme :Yellow Solid PowderMasse moléculaire :212.2WP1066
CAS :WP1066 is a inhibitor of JAK2 (IC50: 2.30 μM) and STAT3 (IC50: 2.43 μM) in HEL cells; shows activity to JAK2, STAT3/5, and ERK1/2, not JAK1 and JAK3.Formule :C17H14BrN3ODegré de pureté :98.92% - 99.73%Couleur et forme :SolidMasse moléculaire :356.22GDC-0214
CAS :GDC-0214 is an inhaled small-molecule JAK1 inhibitor and reduces fractional exhaled nitric oxide (Feno).Formule :C28H28ClF2N9O3Degré de pureté :99.75%Couleur et forme :SolidMasse moléculaire :612.03Ref: TM-T9826
1mg93,00€5mg182,00€10mg269,00€25mg429,00€50mg610,00€100mg820,00€200mg1.099,00€1mL*10mM (DMSO)245,00€Niraparib tosylate monohyrate
CAS :Niraparib (MK-4827), a PARP inhibitor, boosts DNA breaks to trigger genomic instability and apoptosis, offering anti-cancer effects.Formule :C26H30N4O5SDegré de pureté :97.7% - 99.99%Couleur et forme :SolidMasse moléculaire :510.61Ref: TM-T9497
5mg57,00€10mg82,00€25mg111,00€50mg137,00€100mg205,00€200mg309,00€500mg515,00€1mL*10mM (DMSO)66,00€OUL35
CAS :OUL35 (NSC-39047) is a selective PARP-10 inhibitor, and small-molecule ARTD10 inhibitor. OUL35 has been shown to rescue cells from ARTD10-induced cell death.Formule :C14H12N2O3Degré de pureté :99.2%Couleur et forme :SolidMasse moléculaire :256.26BMS-P5 free base
CAS :BMS-P5 free base is a specific and orally active peptidylarginine deiminase 4 (PAD4) inhibitor.Formule :C27H32N6O2Degré de pureté :99.88%Couleur et forme :SolidMasse moléculaire :472.58WIKI4
CAS :WIKI4 is a potent inhibitor of Wnt/β-catenin signaling and tankyrase 2 (TNKS2).Formule :C29H23N5O3SDegré de pureté :99.6% - 99.71%Couleur et forme :SolidMasse moléculaire :521.59Buformin hydrochloride
CAS :Buformin hydrochloride, an oral biguanide antidiabetic, activates AMPK, enhances insulin sensitivity, and inhibits hepatic glucose production.Formule :C6H16ClN5Degré de pureté :97.83%Couleur et forme :SolidMasse moléculaire :193.68Piribedil hydrochloride
CAS :Piribedil HCl treats Parkinson's, circulatory issues, aids cancer research; inhibits MLL1; D2/D3 agonist; α2-antagonist. EC50: 0.18 μM.Formule :C16H19ClN4O2Couleur et forme :SolidMasse moléculaire :334.8AK-1
CAS :AK-1: SIRT2 inhibitor, IC50 12.5 μM, hinders Alzheimer's neurodegeneration, arrests colon cancer cell cycle.Formule :C19H21N3O5SDegré de pureté :98.32% - 99.44%Couleur et forme :SolidMasse moléculaire :403.454-(3-Chlorophenyl)-2(3H)-thiazolone
CAS :4-(3-chlorophenyl)-2,3-dihydro-1,3-thiazol-2-one: a thiazole used to make antifungals, antivirals, and anti-inflammatories.Formule :C9H6ClNOSDegré de pureté :95.311%Couleur et forme :SolidMasse moléculaire :211.67BAY 87-2243
CAS :BAY 87-2243 is a potent and selective inhibitor of hypoxia-inducible factor-1 (HIF-1).Formule :C26H26F3N7O2Degré de pureté :98% - 99.95%Couleur et forme :SolidMasse moléculaire :525.53Ref: TM-T2488
1mg34,00€2mg40,00€5mg59,00€10mg96,00€25mg200,00€50mg334,00€100mg557,00€1mL*10mM (DMSO)70,00€IOX2
CAS :IOX2 is a selective HIF PHD inhibitor, active in cells with 21 nM IC50 for PHD2/ELGN-1, not inhibiting FIH at 20uM.Formule :C19H16N2O5Degré de pureté :98% - 99.59%Couleur et forme :SolidMasse moléculaire :352.34I-CBP112
CAS :I-CBP112 is a specific and potent acetyl-lysine competitive protein-protein interaction inhibitor targeting the CBP/p300 bromodomains.Formule :C27H36N2O5Degré de pureté :98.18%Couleur et forme :SolidMasse moléculaire :468.59Ref: TM-T3969
1mg33,00€2mg50,00€5mg92,00€10mg161,00€25mg296,00€50mg425,00€100mg583,00€200mg785,00€1mL*10mM (DMSO)92,00€FLLL32
CAS :FLLL32 is an effective JAK2/STAT3 inhibitor (IC50 of <5 μM).Formule :C28H32O6Degré de pureté :97% - 97.90%Couleur et forme :SolidMasse moléculaire :464.55Ref: TM-T6838
2mg43,00€5mg63,00€10mg88,00€25mg117,00€50mg187,00€100mg333,00€500mg797,00€1mL*10mM (DMSO)69,00€Eicosapentaenoic Acid sodium
CAS :EPA sodium, an oral omega-3, demethylates DNA, reactivates tumor suppressors, and induces vasodilation.Formule :C20H29NaO2Couleur et forme :SolidMasse moléculaire :324.43Amifostine sodium
CAS :Amifostine sodium is a phosphorothioate proposed as a radiation-protective agent. It causes splenic vasodilation and may block autonomic ganglia.Formule :C5H15N2NaO3PSCouleur et forme :SolidMasse moléculaire :237.21OTS186935 hydrochloride
OTS186935 HCl inhibits SUV39H2 (IC50 6.49 nM), curbs tumor growth in mice, and modulates γ-H2AX in cancer cells.Formule :C25H27Cl2N5O2Couleur et forme :SolidMasse moléculaire :522.31Perindopril
CAS :Perindopril, an ACE inhibitor, treats hypertension, heart failure, and coronary artery disease; available as arginine or erbumine.Formule :C19H32N2O5Couleur et forme :White PowderMasse moléculaire :368.47HNHA
CAS :HNHA is an inhibitor of HDAC.Formule :C17H21NO2SDegré de pureté :98.04%Couleur et forme :SolidMasse moléculaire :303.42Ref: TM-T21806
1mg44,00€5mg84,00€10mg135,00€25mg279,00€50mg445,00€100mg640,00€200mg879,00€1mL*10mM (DMSO)90,00€TIQ-A
CAS :TIQ-A blocks PARP1 to prevent excessive DNA damage response, implicated in ischemia, asthma, and atherosclerosis.Formule :C11H7NOSDegré de pureté :99.75%Couleur et forme :SolidMasse moléculaire :201.24Ref: TM-T50098
1mg52,00€5mg92,00€10mg161,00€25mg290,00€50mg414,00€100mg532,00€200mg737,00€1mL*10mM (DMSO)96,00€4'-Methoxychalcone
CAS :4'-Methoxychalcone with a variety of pharmacological activities, such as anti-tumor and anti-inflammatory activities.Formule :C16H14O2Degré de pureté :99.86%Couleur et forme :SolidMasse moléculaire :238.285-Ph-IAA
CAS :5-Ph-IAA is a derivative of Indole-3-acetic acid (IAA), which is a plant hormone and acts as an enzyme or prodrug combination for cancer gene therapy.
Formule :C16H13NO2Degré de pureté :99.37% - 99.973%Couleur et forme :SolidMasse moléculaire :251.28CPI-455
CAS :CPI-455 is a specific KDM5 inhibitor.Formule :C16H14N4ODegré de pureté :97.87% - 99.03%Couleur et forme :SolidMasse moléculaire :278.31Ref: TM-T3552
1mg34,00€2mg49,00€5mg70,00€10mg105,00€25mg178,00€50mg335,00€100mg505,00€1mL*10mM (DMSO)70,00€A-769662
CAS :A-769662 is an effective, reversible AMPK activator(EC50=0.8 μM).Formule :C20H12N2O3SDegré de pureté :97.52% - 99.58%Couleur et forme :SolidMasse moléculaire :360.39Ref: TM-T2468
2mg37,00€5mg54,00€10mg74,00€25mg135,00€50mg244,00€100mg440,00€500mg964,00€1mL*10mM (DMSO)56,00€TG101209
CAS :TG101209 is a selective JAK2 inhibitor with IC50 of 6 nM.Formule :C26H35N7O2SDegré de pureté :99% - >99.99%Couleur et forme :SolidMasse moléculaire :509.67GSK-J4 Hydrochloride
CAS :GSK-J4 Hydrochloride (GSK J4 HCl) is a cell permeable, potent and selective histone demethylase(JMJD3 )inhibitor. It is an ethyl ester derivative of the GSK-J1.Formule :C24H28ClN5O2Degré de pureté :97.95% - 98.23%Couleur et forme :SolidMasse moléculaire :453.97Ref: TM-T4383
1mg38,00€2mg50,00€5mg84,00€10mg120,00€25mg207,00€50mg344,00€100mg505,00€200mg707,00€1mL*10mM (DMSO)132,00€BAZ1A-IN-1
CAS :BAZ1A-IN-1, a potent inhibitor, KD 0.52 μM against BAZ1A, is effective in high-BAZ1A cancer cells, not in low-BAZ1A ones.Formule :C16H12N4O3SDegré de pureté :99.87%Couleur et forme :SolidMasse moléculaire :340.36Ref: TM-T9552
1mg84,00€5mg177,00€10mg268,00€25mg537,00€50mg803,00€100mg1.099,00€200mg1.468,00€1mL*10mM (DMSO)195,00€BMS-P5
CAS :BMS-P5 is a specific and orally active Peptidylarginine Deiminase 4 (PAD4) inhibitor.Formule :C27H33ClN6O2Degré de pureté :99.88%Couleur et forme :SolidMasse moléculaire :509.04Ref: TM-T22277
2mg44,00€5mg86,00€10mg136,00€25mg268,00€50mg479,00€100mg760,00€200mg1.018,00€1mL*10mM (DMSO)96,00€Palmatine chloride
CAS :Palmatine chloride an isoquinoline alkaloid, is an important medicinal herbal extract with diverse pharmacological and biological properties.Formule :C21H22ClNO4Degré de pureté :97.9% - 99.47%Couleur et forme :SolidMasse moléculaire :387.86Rucaparib
CAS :Rucaparib (PF-01367338) is a orally PARP inhibitor and a H6PD inhibitor. Rucaparib exhibits antitumor activity against CRPC. Cost-effective and quality-assured.Formule :C19H18FN3ODegré de pureté :98.24% - 99.80%Couleur et forme :SolidMasse moléculaire :323.36Ref: TM-T4463
2mg46,00€5mg70,00€10mg109,00€25mg170,00€50mg222,00€100mg344,00€200mg512,00€500mg823,00€1mL*10mM (DMSO)77,00€ASP4132
CAS :ASP4132 is an orally active AMPK activator (EC50 : 18 nM), has anti-cancer activity.Formule :C46H51F3N6O8S2Degré de pureté :98.34%Couleur et forme :SolidMasse moléculaire :937.06Ref: TM-T8432
1mg50,00€5mg114,00€10mg177,00€25mg321,00€50mg482,00€100mg677,00€200mg928,00€1mL*10mM (DMSO)185,00€JW 55
CAS :JW 55 (JW55) is an effective and selective β-catenin signaling pathway inhibitor, works by inhibition of the PARP domain of tankyrase 1 and tankyrase 2 (TNKS1/2Formule :C25H26N2O5Degré de pureté :99.31% - 99.76%Couleur et forme :SolidMasse moléculaire :434.48GSK591
CAS :GSK591 (GSK3203591), Alternative Names are EPZ015866, GSK3203591, is a potent selective inhibitor of the arginine methyltransferase PRMT5 (IC50=11 nM).Formule :C22H28N4O2Degré de pureté :99.35% - 99.45%Couleur et forme :SolidMasse moléculaire :380.48Ref: TM-T6853
1mg46,00€2mg58,00€5mg95,00€10mg137,00€25mg268,00€50mg404,00€100mg567,00€1mL*10mM (DMSO)101,00€CP21R7
CAS :CP21 is a specific GSK3β inhibitor, used to activate stem cells for differentiation, often paired with BMP4 for mesodermal fate.Formule :C19H15N3O2Degré de pureté :96.14% - 99.16%Couleur et forme :SolidMasse moléculaire :317.34Ref: TM-T3684
1mg38,00€2mg50,00€5mg84,00€10mg120,00€25mg236,00€50mg356,00€100mg537,00€1mL*10mM (DMSO)77,00€IDF-11774
CAS :IDF-11774 is a HIF-1 inhibitor.It reduces hif-1α HRE luciferase activity (IC50 = 3.65 μM).Formule :C23H32N2O2Degré de pureté :98.05%Couleur et forme :SolidMasse moléculaire :368.51SC99
CAS :SC99 inhibits JAK2-STAT3, reducing STAT3 genes, platelet activity, and has anti-myeloma, anti-thrombotic effects.Formule :C15H8Cl2FN3ODegré de pureté :99.56%Couleur et forme :SolidMasse moléculaire :336.15Ref: TM-T8719
1mg43,00€5mg87,00€10mg133,00€25mg227,00€50mg344,00€100mg429,00€200mg597,00€1mL*10mM (DMSO)94,00€FM-381
CAS :FM381, a JAK3 inhibitor with 127 pM IC50, is 410-3600x more selective over JAK1/2/TYK2.Formule :C24H24N6O2Degré de pureté :98.44%Couleur et forme :SolidMasse moléculaire :428.49Ref: TM-T5091
1mg47,00€2mg62,00€5mg92,00€10mg128,00€25mg212,00€50mg319,00€100mg485,00€1mL*10mM (DMSO)107,00€Benzamide
CAS :Benzamide (Amid kyseliny benzoove), an inhibitor of poly(ADP-ribose) polymerase, is a derivative of benzoic acid.Formule :C7H7NODegré de pureté :99.66%Couleur et forme :Colorless Crystals Physical Description White Powder (Ntp 1992)Masse moléculaire :121.14(+)-JQ-1
CAS :(+)-JQ-1 (JQ1) is a BET bromine domain inhibitor that inhibits BRD4 (1/2) (IC50=77/33 nM) with specificity and reversibility.Formule :C23H25ClN4O2SDegré de pureté :97.57% - 99.97%Couleur et forme :SolidMasse moléculaire :456.99Ref: TM-T2110
1mg34,00€2mg42,00€5mg57,00€10mg74,00€25mg90,00€50mg137,00€100mg178,00€200mg268,00€500mg485,00€1mL*10mM (DMSO)63,00€PF-06409577
CAS :PF-06409577 is an effective, orally active, and specific allosteric activator of AMPK (EC50: 7 nM, for α1β1γ1).Formule :C19H16ClNO3Degré de pureté :95.17% - 98.21%Couleur et forme :SolidMasse moléculaire :341.79Ref: TM-T4427
1mg34,00€2mg43,00€5mg63,00€10mg100,00€25mg200,00€50mg334,00€100mg537,00€200mg762,00€1mL*10mM (DMSO)71,00€BEBT-908
CAS :BEBT-908 (PI3Kα inhibitor 1) is a selective PI3Kα inhibitor (IC50 <0.1 μM). BEBT-908 also inhibits HDAC (0.1 μM≤IC50≤1 μM).Formule :C23H25N9O3SDegré de pureté :99.67%Couleur et forme :SolidMasse moléculaire :507.57Ref: TM-T16529
1mg94,00€5mg222,00€10mg334,00€25mg562,00€50mg802,00€100mg1.063,00€200mg1.459,00€1mL*10mM (DMSO)249,00€TAK-632
CAS :TAK-632 is a potent pan-Raf inhibitor.Formule :C27H18F4N4O3SDegré de pureté :98% - 99.5%Couleur et forme :SolidMasse moléculaire :554.52KG-501
CAS :KG-501 (Naphthol AS-E phosphate) is a cAMP response element-binding protein (CREB) inhibitor(IC50 : 6.89 μM).Formule :C17H13ClNO5PDegré de pureté :97.81%Couleur et forme :SolidMasse moléculaire :377.72Delgocitinib EtOH
CAS :Delgocitinib (LEO-124249/JTE052) is a selective JAK inhibitor used for reducing skin inflammation and treating chronic dermatitis.Formule :C18H24N6O2Couleur et forme :SolidMasse moléculaire :356.43Isoxazole
CAS :Isoxazole (1,2-oxazole) is the inhibitor of acetylcholinesterase (AChE). The ligands of Isoxazole bind to and inhibit the Sxc- antiporter.Formule :C3H3NODegré de pureté :98% - 99.34%Couleur et forme :Colorless LiquidMasse moléculaire :69.06Tazemetostat hydrobromide
CAS :Tazemetostat hydrobromide: potent, selective EZH2 inhibitor; blocks PRC2/wild-type EZH2 (Ki: 2.5 nM) & EZH1 (IC50: 392 nM).Formule :C34H45BrN4O4Degré de pureté :99.8%Couleur et forme :SolidMasse moléculaire :653.65Ref: TM-T17002
2mg40,00€5mg57,00€10mg77,00€50mg90,00€100mg150,00€200mg219,00€500mg358,00€1mL*10mM (DMSO)79,00€
