
Chromatine/Épigénétique
Sous-catégories appartenant à la catégorie "Chromatine/Épigénétique"
2547 produits trouvés pour "Chromatine/Épigénétique"
BAZ2-ICR
CAS :BAZ2-ICR is an epigenetic chemical probe and it also is a potent, selective, cell active and orally active BAZ2A/B bromodomains inhibitor with IC50s of 130 nM and 180 nM, and Kds of 109 nM and 170 nM, respectively. BAZ2-ICR shows 10-15-fold selectivity for binding BAZ2A/B over CECR2 and >100-fold selectivity over all other bromodomains.Formule :C20H19N7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :357.41Antitumor agent-104
CAS :Antitumor Agent-104 (Compound 9) serves as an antineoplastic by impeding DNA repair mechanisms in tumor cells, primarily through the inhibition of PARP1 enzyme
Formule :C31H33FN6O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :556.63Igermetostat
CAS :Igermetostat, an EZH2 inhibitor, is utilized both in vivo and in vitro for cancer research [1].
Formule :C32H46N4O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :550.73BET-IN-14
CAS :BET-IN-14 is a pan BET inhibitor with an IC50 of 5.35 nM, demonstrating oral activity and anticancer properties [1].
Formule :C30H37N7O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :527.66BB-Cl-Amidine hydrochloride
CAS :BB-Cl-Amidine hydrochloride is an inhibitor of peptidylarginine deminase (PAD) [1].Formule :C26H27Cl2N5ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :496.43PARP7-IN-16 free base
CAS :PARP7-IN-16 free base is the freebase form of PARP7-IN-16. As a selective oral inhibitor of PARP-1/2/7, it demonstrates IC50 values of 0.94, 0.87, and 0.21 nM, respectively. This compound is utilized in the research of breast and prostate cancer.
Formule :C25H27FN4O4Couleur et forme :SolidMasse moléculaire :466.50BET BD2-IN-3
CAS :BET BD2-IN-3 (compound I-58), a BET inhibitor specifically targeting the BD2 domain, can be radiolabeled with [11C] for use in positron emission tomography (PET) imaging. PET studies with [11C]BD2-IN-3 in mice have demonstrated appropriate biodistribution in peripheral organs and tissues.
Formule :C29H30N4OCouleur et forme :SolidMasse moléculaire :450.58
