Altération de l'ADN/réparation de l'ADN
Les inhibiteurs de la réparation des dommages à l'ADN sont des composés qui interfèrent avec les processus impliqués dans la détection et la réparation des dommages à l'ADN. Ces inhibiteurs sont essentiels pour étudier les mécanismes de la stabilité génomique, de la mutagenèse et de la réponse aux dommages à l'ADN. Ils sont également importants dans la recherche sur le cancer, car de nombreuses tumeurs dépendent de voies spécifiques de réparation de l'ADN pour survivre. En inhibant ces voies, les inhibiteurs de la réparation des dommages à l'ADN peuvent améliorer l'efficacité de la chimiothérapie et de la radiothérapie. Chez CymitQuimica, nous offrons une large gamme d'inhibiteurs de haute qualité de la réparation des dommages à l'ADN pour soutenir vos recherches en biologie moléculaire, oncologie et pharmacologie.
Sous-catégories appartenant à la catégorie "Altération de l'ADN/réparation de l'ADN"
- ATM/ATR(71 produits)
- Alkylation de l'ADN(11 produits)
- Méthyltransférase de l’ADN(421 produits)
- Gyrase de l’ADN(11 produits)
- ADN-PK(51 produits)
- MTH1(1 produits)
- Antimétabolite nucléosidique/analogue(1.388 produits)
- Transcriptase inverse(43 produits)
- Sirtuine(88 produits)
- Télomérase(33 produits)
- Topoisomérase(136 produits)
Affichez 3 plus de sous-catégories
957 produits trouvés pour "Altération de l'ADN/réparation de l'ADN"
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Carboxy-pyridostatin 2HCl
<p>Carboxy-pyridostatin 2HCl has potential antitumor activity with high affinity for DNA at DNA G4s.</p>Formule :C35H36Cl2N10O7Degré de pureté :97.12% - 99.10%Couleur et forme :SoildMasse moléculaire :779.63Prednimustine
CAS :<p>Prednimustine (Leo 1031; NSC 134087), an ester of Prednisolone and Chlorambucil, is used in leukemia and lymphoma studies.</p>Formule :C35H45Cl2NO6Couleur et forme :SolidMasse moléculaire :646.64Tertomotide hydrochloride
CAS :<p>Tertomotide (GV1001) hydrochloride is a peptide vaccine composed of a 16-amino acid sequence from human telomerase reverse transcriptase (hTERT). It exhibits neuroprotective properties and has potential for research in Alzheimer's disease.</p>Formule :C85H147ClN26O21Couleur et forme :SolidMasse moléculaire :1904.69Antitumor agent-63
CAS :<p>Compound 40, a non-toxic 20(S)-O-CPT glycoconjugate, is stable, with low Topo I inhibition.</p>Formule :C38H46N4O18Couleur et forme :SolidMasse moléculaire :846.79Monascin
CAS :<p>Monascin: azaphilonoid in red-mold rice; anti-tumor and anti-inflammatory.</p>Formule :C21H26O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :358.43AZD-5099
CAS :<p>AZD-5099 is a DNA gyrase modulator potentially for the treatment of bacterial infection.</p>Formule :C21H27Cl2N5O6SCouleur et forme :SolidMasse moléculaire :548.44PR-104 sodium
CAS :<p>PR-104 sodium: hypoxia-activated, tumor-targeting pre-prodrug; turns into PR-104A for research.</p>Formule :C14H19BrN4NaO12PSCouleur et forme :SolidMasse moléculaire :601.25AuL1
<p>AuL1 is a topoisomerase IIα (Top II) inhibitor with DNA intercalating properties. It exhibits cytotoxic effects on tumor cells, making it a potential subject for anticancer agent research.</p>Formule :C29H50AuCl2N5Couleur et forme :SolidMasse moléculaire :736.61ACT-387042
CAS :<p>ACT-387042 is a Bacterial Topoisomerase Inhibitor, it has broad-spectrum activity against Gram-positive and Gram-negative bacteria.</p>Formule :C23H26FN5O4SCouleur et forme :SolidMasse moléculaire :487.55MC3343
CAS :<p>MC3343, a DNMT1/3A inhibitor, affects tumor proliferation by blocking osteosarcoma cells in the G1 or G2/M phase and induces osteogenic differentiation.</p>Formule :C27H23N7ODegré de pureté :99.73%Couleur et forme :SolidMasse moléculaire :461.52PPARγ/GR modulator 1
<p>PPARγ/GR Modulator 1, an orally active dual agonist for the Peroxisome Proliferator-Activated Receptor Gamma (PPARγ) and Glucocorticoid Receptor (GR), exhibits</p>Formule :C14H10FNO4Couleur et forme :SolidMasse moléculaire :275.23WAY-323061
CAS :<p>WAY-323061 is a SIRT2 inhibitor.</p>Formule :C25H21N5O2SDegré de pureté :99.33%Couleur et forme :SolidMasse moléculaire :455.53Elomotecan hydrochloride
CAS :<p>Elomotecan hydrochloride (BN 80927), a potent hCPT analog, inhibits topoisomerases I/II, outperforming other anticancer drugs.</p>Formule :C29H33Cl2N3O4Couleur et forme :SolidMasse moléculaire :558.5Martinostat
CAS :<p>Martinostat is an HDAC inhibitor that can be radiolabeled for quantitative imaging of HDACs within the central nervous system and major peripheral organs.</p>Formule :C22H30N2O2Couleur et forme :SolidMasse moléculaire :354.49Elinafide
CAS :<p>Elinafide, a dinaphthylimide cytotoxic agent, is a DNA-targeted anticancer agent that has shown antitumor activity in in vitro and in vivo assays.</p>Formule :C31H28N4O4Degré de pureté :97.29%Couleur et forme :SolidMasse moléculaire :520.58Sulotroban
CAS :<p>sulotroban is a TXA2 receptor antagonist that acts synergistically with iloprost to inhibit TXA2-dependent platelet activation.</p>Formule :C16H17NO5SDegré de pureté :98.86% - 99.88%Couleur et forme :SolidMasse moléculaire :335.37BML-278
CAS :<p>BML-278 is a SIRT1 activator with an EC150 of 1 μM.BML-278 increases H3K9 methylation and inhibits H3K9 acetylation in parental and maternal prokaryotes, and</p>Formule :C24H25NO4Degré de pureté :99.53%Couleur et forme :SolidMasse moléculaire :391.46PNU-142586
CAS :<p>PNU-142586 is a bio-active chemical.</p>Formule :C16H20FN3O6Couleur et forme :SolidMasse moléculaire :369.34Amrubicin
CAS :<p>The compound is a synthetic anthracycline antibiotic. It inhibits DNA topoisomerase II.</p>Formule :C25H25NO9Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :483.47Gimatecan HCl
<p>Gimatecan HCl (ST1481 HCL) is a potent topoisomerase I inhibitor. Gimatecan is an orally bioavailable camptothecin analogue with antitumor activity.</p>Formule :C25H26ClN3O5Degré de pureté :97.04%Couleur et forme :SoildMasse moléculaire :483.94DNA Damage & Repair Compound Library
<p>A unique collection of xnum DNA Damage &amp; Repair related compounds for high throughput screening (HTS) and high content screening (HCS);</p>Couleur et forme :Odour SolidGK444
<p>GK444 (Compound 15a), a selective HDAC1/2 inhibitor with IC50 values of 100 nM and 92 nM for HDAC1 and HDAC2 respectively, demonstrates an IC50 of 4.1 μM in</p>Degré de pureté :98%Couleur et forme :Odour SolidBanoxantrone (D12)
CAS :<p>Banoxantrone D12, deuterium-labeled version, reduces to AQ4 - a stable DNA-targeting topoisomerase II inhibitor.</p>Formule :C22H28N4O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :456.55VH 032 amide-PEG1-acid
CAS :<p>VHL ligand for PROTAC R&D; E3 ligase with PEG1 linker and carboxylic acid for target conjugation.</p>Formule :C28H38N4O7SCouleur et forme :SolidMasse moléculaire :574.69CUDA disodium
<p>CUDA disodium is an effective, soluble epoxide hydrolase (sEH) inhibitor, with IC50 values of 11.1 nM for murine sEH and 112 nM for human sEH. It selectively enhances the activity of peroxisome proliferator-activated receptor PPARalpha. CUDA disodium may be valuable for cardiovascular disease research.</p>Couleur et forme :Odour SolidPericosine A
CAS :<p>Pericosine A, a fungal metabolite from P. byssoides, shows anticancer effects (GI50s = 0.05-24.55 μM) and EGFR inhibition (40-70% at 100 μg/ml).</p>Formule :C8H11ClO5Couleur et forme :SolidMasse moléculaire :222.62GK718
<p>GK718, a selective HDAC1/3 inhibitor with IC50 values of 259 nM and 139 nM, respectively, elevates acetylated histone H3 levels in cells and mitigates Bleomycin</p>Degré de pureté :98%Couleur et forme :Odour SolidHDAC6-IN-19
<p>HDAC6-IN-19 (Compound 14g), an HDAC6 inhibitor with an IC50 of 2.68 nM, additionally inhibits HDAC1, HDAC2, and HDAC3, with IC50 values of 61.6 nM, 98.7 nM, and</p>Formule :C26H23ClN4O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :474.94NH2-bicyclo[1.1.1]pentane-7-MAD-MDCPT hydrochloride
<p>Compound I, NH2-bicyclo[1.1.1]pentane-7-MAD-MDCPT hydrochloride, is a topoisomerase I inhibitor that demonstrates effective antibody-drug conjugate (ADC)</p>Formule :C26H24ClN3O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :509.94HDAC6-IN-25
<p>HDAC6-IN-25 (compound 8) is a potent and selective HDAC6 inhibitor, exhibiting an IC50 value of 0.6 nM [1].</p>Degré de pureté :98%Couleur et forme :Odour SolidKetopioglitazone
CAS :<p>Ketopioglitazone is an active metabolite of pioglitazone.</p>Formule :C19H18N2O4SCouleur et forme :SolidMasse moléculaire :370.42Sirt1/2-IN-4
<p>Sirt1/2-IN-4 (compound PS3) is a potent triple inhibitor of SIRT1, SIRT2, and SIRT3, exhibiting IC50 values of 1.2 μM (SIRT1), 1.9 μM (SIRT2), and 18.6 μM (</p>Formule :C21H20N4O3S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :440.54CL2-MMT-SN38
CAS :<p>CL2-MMT-SN38 is a derivative of SN-38, which is a potent anticancer agent and the active metabolite of Irinotecan (CPT-11), a Topoisomerase I inhibitor.</p>Formule :C102H122N12O24Couleur et forme :SolidMasse moléculaire :1900.158GW 1929 hydrochloride
CAS :<p>Oral PPARγ agonist with pEC50 of 8.05; low affinity for PPARα, PPARδ. Reduces blood glucose, fatty acids, triglycerides in vivo.</p>Formule :C30H30ClN3O4Couleur et forme :SolidMasse moléculaire :532.04Tibesaikosaponin V
CAS :<p>TKV, a triterpene diglycoside from Bupleurum chinense, curbs lipid build-up and fat content in adipocytes without harm and hinders fat cell differentiation.</p>Formule :C42H68O15Couleur et forme :SolidMasse moléculaire :812.9820-carboxy Arachidonic Acid
CAS :<p>20-COOH-AA, 20-HETE metabolite, inhibits kidney ion transport, relaxes constricted vessels, and activates PPARα/γ.</p>Formule :C20H30O4Couleur et forme :SolidMasse moléculaire :334.456HDAC-IN-61
<p>HDAC-IN-61 (compound 12k) is a potent, orally active inhibitor of histone deacetylase (HDAC) with anticancer activity, exhibiting an IC50 of 30 nM against Bel-</p>Formule :C28H27N3O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :485.53SGC-UBD253
<p>SGC-UBD253 is a potent antagonist of the HDAC6-UBD interaction and may be utilized in cancer research [1].</p>Formule :C21H20ClN3O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :429.85FKB04
<p>FKB04 is a telomeric repeat binding factor 2 (TRF2) inhibitor that exerts its antitumor activity by disrupting the telomere maintenance mechanisms in hepatocellular carcinoma cells. This leads to T-loop defects, inducing telomere shortening and cellular senescence. Additionally, FKB04 inhibits tumor growth in a human liver cancer xenograft mouse model (by implanting Huh-7 cells in BALB/c mice). This compound is utilized in research focused on liver cancer.</p>Couleur et forme :Odour SolidDNMT1/HDAC-IN-1
<p>DNMT1/HDAC-IN-1 (compound (R)-23a), a potent dual inhibitor targeting both DNMT1 and HDAC, exhibits impressive inhibitory effects specifically on HDAC1 (HDAC1:IC50=0.05 μM), a major HDAC isoform that interacts with DNMT1 across multiple protein complexes involved in the transcriptional silencing of TSGs. This compound has been shown to remodel the tumor immune microenvironment and induce tumor regression, effectively reversing cancer-specific epigenetic abnormalities.</p>Couleur et forme :Odour SolidHeliotrine N-oxide
CAS :<p>Heliotrine N-oxide, a PA N-oxide, triggers pyrrolic DNA adducts and may cause liver tumors.</p>Formule :C16H27NO6Couleur et forme :SolidMasse moléculaire :329.393Topoisomerase I/II inhibitor 5
<p>TopoisomeraseI/II inhibitor 5 (compound 1) stabilizes G4 structures through binding and concurrently inhibits the relaxation activities of TopoI and II.</p>Couleur et forme :Odour SolidSIRT-IN-5
<p>SIRT-IN-5, a selective inhibitor of SIRT3 with an IC50 of 2.88 μM, facilitates the differentiation of multiple myeloma cells. This differentiation is associated with increased expression of the differentiation antigens CD49e and human immunoglobulin light chains λ and κ.</p>Couleur et forme :Odour SolidElomotecan
CAS :<p>Elomotecan (BN 80927 free base) is a potent inhibitor of topoisomerases I and II.Cost-effective and quality-assured.</p>Formule :C29H32ClN3O4Couleur et forme :SolidMasse moléculaire :522.04PARP/HDAC-IN-1
<p>PARP/HDAC-IN-1 is a PARP and HDAC inhibitor that inhibits PARP1, PARP2, and HDAC1, and may be used to study pancreatic cancer.</p>Formule :C36H32F2N6O3Degré de pureté :95.00%Couleur et forme :SolidMasse moléculaire :634.67Gemfibrozil 1-O-β-glucuronide
CAS :<p>Gemfibrozil 1-O-β-Glucuronide, a metabolite of Gemfibrozil , is a potent and competitive P450 (CYP) isoform CYP2C8 inhibitor with an IC50 of 4.07 μM.</p>Formule :C21H30O9Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :426.461-Methyladenosine-d3
<p>1-Methyladenosine-d3 hydrochloride is the hydrochloride salt form of deuterium-labeled 1-Methyladenosine. This compound is a modification of RNA that serves as a biomarker for tumors, with elevated levels in the body linked to cancer development. Upon methylation, 1-Methyladenosine upregulates the expression of PPARδ, regulates cholesterol metabolism, and activates the Hedgehog signaling pathway, thereby driving the onset of liver tumors.</p>Couleur et forme :Odour SolidIC 86621
CAS :<p>IC 86621: DNA-PK ATP-competitive inhibitor, IC50 120 nM, enhances DSB antitumor effects, EC50 68 µM for repair.</p>Formule :C12H15NO3Degré de pureté :99.68%Couleur et forme :SolidMasse moléculaire :221.25Anticancer agent 177
<p>Anticanceragent 177 (Compound 11b) is an NAMPT inhibitor and DNA alkylating agent with antitumor activity both in vitro and in vivo.</p>Formule :C28H36Cl2N4O2Masse moléculaire :530.22153Murrayanol
<p>Murrayanol is a useful organic compound for research related to life sciences and the catalog number is T125851.</p>Formule :C24H29NO2Couleur et forme :SolidMasse moléculaire :363.501Stearolic acid
CAS :<p>Stearolic acid is a useful organic compound for research related to life sciences. The catalog number is T124753 and the CAS number is 506-24-1.</p>Formule :C18H32O2Couleur et forme :SolidMasse moléculaire :280.452MS9024
<p>MS9024 is a degrader of DNA methyltransferase 1 (DNMT1), facilitating its degradation in HCT116 cells via the ubiquitin-proteasome pathway, with a DC50 of 35 nM (DC50 values are 254 nM in MDA-MB-468 and 101 nM in H1299). Additionally, MS9024 inhibits DNMT1 with an IC50 of 0.43 μM.</p>Couleur et forme :Odour Solid23-epi-26-Deoxyactein
CAS :<p>23-epi-26-Deoxyactein is a naturally occurring compound exhibiting anti-obesity and anti-cancer properties when administered orally [1] [2] [3].</p>Formule :C37H56O10Couleur et forme :SolidMasse moléculaire :660.83(±)9-HEPE
CAS :<p>(±)9-HEPE is produced by non-enzymatic oxidation of EPA.</p>Formule :C20H30O3Couleur et forme :SolidMasse moléculaire :318.457Colibactin 742
CAS :<p>Colibactin 742, a stable derivative of colibactin, efficiently induces DNA interstrand cross-links, activates the Fanconi Anemia DNA repair pathway, and leads</p>Formule :C37H42N8O5S2Couleur et forme :SolidMasse moléculaire :742.91PARP10-IN-3
CAS :<p>PARP10-IN-3: selective inhibitor for mono-ADP-ribotransferase PARP10 (IC50: 480nM), also affects PARP2 and PARP15 (IC50: 1.7μM).</p>Formule :C14H12N2O3Degré de pureté :99.41%Couleur et forme :SoildMasse moléculaire :256.26Anti-obesity agent 1
<p>Compound 4 (Anti-obesity agent 1) demonstrates potential for enhanced lipolysis, highlighting its anti-obesity characteristics.</p>Formule :C21H22N2O6Couleur et forme :SolidMasse moléculaire :398.409HDAC-IN-78
<p>HDAC-IN-78 (compound 66a) is an HDAC inhibitor utilized for cancer research.</p>Couleur et forme :Odour SolidPhosphoramide mustard
CAS :<p>Phosphoramide mustard is a toxic metabolite of cyclophosphamide with anticancer activity and ovarian toxicity that induces DNA damage.</p>Formule :C4H11Cl2N2O2PDegré de pureté :93.00%Couleur et forme :SolidMasse moléculaire :221.02BRD7586
CAS :<p>BRD7586 is a cell-permeable small molecule inhibitor of SpCas9 that enhances SpCas9 specificity.</p>Formule :C17H14ClN3O3S2Degré de pureté :97.70% - 99.03%Couleur et forme :SolidMasse moléculaire :407.89(4-NH2)-Exatecan
CAS :<p>(4-NH2)-Exatecan is a topoisomerase inhibitor with potential anticancer activity for the synthesis of antibody drug conjugates (ADCs).</p>Formule :C23H21N3O4Degré de pureté :99.89%Couleur et forme :SolidMasse moléculaire :403.43VK-1727
<p>VK-1727 inhibits EBNA1 DNA binding, reducing proliferation of EBV-positive cells while sparing EBV-negative cells, useful for multiple sclerosis research.</p>Formule :C29H25NO4Degré de pureté :98.074%Couleur et forme :SolidMasse moléculaire :451.512'-Deoxy-2'-fluoro-β-D-arabinocytidine hydrochloride
CAS :<p>2'-Deoxy-2'-fluoro-beta-D-arabinocytidine HCl inhibits DNA methyltransferase with potential anti-tumor properties.</p>Formule :C9H13ClFN3O4Degré de pureté :99.69%Couleur et forme :SolidMasse moléculaire :281.67O6BTG-octylglucoside
CAS :<p>O6BTG-octylglucoside is a potent O6-methylguanine-DNAmethyl-transferase (MGMT) inhibitor (IC50s: 10 nM and 32 nM in HeLa S3 cells and in vitro (cell extracts)).</p>Formule :C24H34BrN5O7SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :616.53Banoxantrone dihydrochloride
CAS :<p>Banoxantrone dihydrochloride (AQ4N dihydrochloride) is a novel hypoxic cytotoxin that selectively kills hypoxic cells through an iNOS-dependent mechanism.</p>Formule :C22H30Cl2N4O6Degré de pureté :99.88%Couleur et forme :SolidMasse moléculaire :517.4HDAC-IN-4
CAS :<p>HDAC-IN-4 is a selective HDAC6 and HDAC10 inhibitor (pIC50s: 7.2 and 6.8 in BRET assay) with antitumoral activity.</p>Formule :C20H21N3O2Couleur et forme :SolidMasse moléculaire :335.4Heptaplatin
CAS :<p>Heptaplatin, an anticancer platinum compound, counters many cancers, including cisplatin-resistant types, with a 17% response rate and tolerable toxicity.</p>Formule :C11H20N2O6PtCouleur et forme :White Crystalline PowderMasse moléculaire :471.365'-O-(4,4'-Dimethoxytrityl)-2'-deoxyuridine
CAS :<p>5'-O-DMT-dU, a dUTPase inhibitor (Ki > 1 mM) for E. coli, is used in DNA synthesis.</p>Formule :C30H30N2O7Couleur et forme :SolidMasse moléculaire :530.57SIRT5 inhibitor 3
CAS :<p>SIRT5 inhibitor 3 is potent and competitive by inhibiting SIRT5 deacetylation, with potential in metabolic, cancer, neurodegenerative, cardiovascular .</p>Formule :C22H12FN3O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :401.35(R)-(+)-Bay-K-8644
CAS :<p>(R)-(+)-Bay-K-8644, a Ca2+ channel agonist, is a dihydropyridine agonist that induces central respiratory depression and inhibits platelet activation in cats.</p>Formule :C16H15F3N2O4Degré de pureté :96.51% - 96.51%Couleur et forme :SolidMasse moléculaire :356.3CP-868388 free base
CAS :<p>CP-868388 free base (CP-868388) is a PPARα agonist with hypolipidemic and anti-inflammatory activity and is used in the study of dyslipidemia.</p>Formule :C26H33NO5Degré de pureté :99.84%Couleur et forme :SolidMasse moléculaire :439.54Balaglitazone
CAS :<p>Balaglitazone is a PPARγ agonist that regulates blood glucose and is used in studies of heart failure and myocardial infarction.</p>Formule :C20H17N3O4SDegré de pureté :99.74%Couleur et forme :SolidMasse moléculaire :395.43Methyl methanesulfonate (Standard)
CAS :<p>Methyl methanesulfonate (Standard) is a standard material used in the analysis of methyl methanesulfonate, typically referenced in its research and analysis.</p>Formule :C2H6O3SCouleur et forme :SolidMasse moléculaire :110.13Gepotidacin
CAS :<p>Gepotidacin is a triazaacenaphthylene antibacterial inhibiting bacterial type II topoisomerase with lower resistance potential than fluoroquinolones.</p>Formule :C24H28N6O3Degré de pureté :99.88%Couleur et forme :SolidMasse moléculaire :448.52AMA-37
CAS :<p>AMA-37 is a selective, reversible, and ATP-competitive DNA-PK inhibitor.</p>Formule :C17H17NO3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :283.32Daun02
CAS :<p>Daun02 is the topoisomerase inhibitor Daunorubicin prodrug.</p>Formule :C41H44N2O20Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :884.79Gancaonin L
CAS :<p>Gancaonin L is a natural product that can be used as a reference standard. The CAS number of Gancaonin L is 129145-50-2.</p>Formule :C20H18O6Couleur et forme :SolidMasse moléculaire :354.3589-Hydroxyellipticin free base
CAS :<p>9-hydroxyellipticine is a potent cytotoxic and antitumor agent. 9-hydroxyellipticine is a 9-hydroxy derivative of ellipticine.</p>Formule :C17H14N2OCouleur et forme :SolidMasse moléculaire :262.31Phosphoramide mustard cyclohexanamine
CAS :<p>Phosphoramide mustard cyclohexanamine is active metabolite of cyclophosphamide, an alkylating agent that cross-links DNA strands,causes cell death, antitumor.</p>Formule :C10H24Cl2N3O2PDegré de pureté :95%Couleur et forme :SolidMasse moléculaire :320.2RPR121056
CAS :<p>RPR121056 is a Irinotecan metabolite, which is generated by CYP3A4. Irinotecan is an antineoplastic agent that inhibits topoisomerase type I.</p>Formule :C33H38N4O8Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :618.68Gatifloxacin mesylate
CAS :<p>Gatifloxacin mesylate, a 4th-gen fluoroquinolone antibiotic, inhibits DNA gyrase and topoisomerase IV.</p>Formule :C20H26FN3O7SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :471.5Gatifloxacin sesquihydrate
CAS :<p>Gatifloxacin sesquihydrate, a bacterial DNA gyrase inhibitor, is used to treat tuberculosis and pneumonia.</p>Formule :C19H24FN3O5Couleur et forme :SolidMasse moléculaire :393.41Telomerase-IN-3
CAS :<p>Telomerase-IN-3 is an inhibitor of telomerase.</p>Formule :C19H16ClN5O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :397.82Epitalon
CAS :<p>Epithalon (also known as Epitalon or Epithalone) is the synthetic version of the polypeptide Epithalamin which is naturally produced in the pineal gland.</p>Formule :C14H22N4O9Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :390.35(R)-GSK-3685032
CAS :<p>(R)-GSK-3685032 is a selective, reversible DNMT1 inhibitor, non-covalent, IC50: 0.036 μM; reduces DNA methylation, inhibits cancer growth.</p>Formule :C22H24N6OSCouleur et forme :SolidMasse moléculaire :420.54Ciprofloxacin hydrochloride monohydrate
CAS :<p>Ciprofloxacin hydrochloride monohydrate (Bay-09867 hydrochloride monohydrate) is a fluoroquinolone antibiotic with potent antibacterial activity.</p>Formule :C17H21ClFN3O4Degré de pureté :99.23% - 99.85%Couleur et forme :White Or Yellowish Crystalline PowderMasse moléculaire :385.82PTGR2-IN-1
CAS :<p>PTGR2-IN-1 is a potent inhibito of PTGR2r. PTGR2-IN-1 increases 15-keto-PGE2-dependent PPARγ transcriptional activity in PTGR2-transfected HEK293T cells.</p>Formule :C19H22N2O2Degré de pureté :99.13%Couleur et forme :SolidMasse moléculaire :310.39YK-3-237
CAS :<p>YK-3-237 (B-[2-Methoxy-5-[(1E)-3-oxo-3-(3,4,5-trimethoxyphenyl)-1-propen-1-yl]phenyl]boronic acid) reduces acetylation of mtp53 and exhibits anti-proliferative</p>Formule :C19H21BO7Degré de pureté :99.47%Couleur et forme :SolidMasse moléculaire :372.18Pentamidine dihydrochloride
CAS :<p>Pentamidine dihydrochloride (MP-601205 dihydrochloride) is an aromatic diamidine agent with activity against a number of microorganisms including protozoa (</p>Formule :C19H26Cl2N4O2Degré de pureté :99.80%Couleur et forme :SolidMasse moléculaire :413.34Pixantrone dimaleate
CAS :<p>Pixantrone dimaleate (Pixantrone Maleate) (BBR 2778 dimaleate) is an experimental antineoplastic drug.</p>Formule :C25H27N5O10Degré de pureté :98.70% - 99.11%Couleur et forme :SolidMasse moléculaire :557.21Silver sulfadiazine
CAS :<p>Silver sulfadiazine (Dermazin) is a sulfonamide-based topical agent with antibacterial and antifungal activity.</p>Formule :C10H9AgN4O2SDegré de pureté :99.04% - 99.58%Couleur et forme :SolidMasse moléculaire :357.14BYK204165
CAS :<p>BYK204165 (RT-017290) is a potent PARP inhibitor (PARP1; IC50 = 44.67 nM for human recombinant PARP1 in an enzyme assay)</p>Formule :C15H12N2O2Degré de pureté :99.61%Couleur et forme :SolidMasse moléculaire :252.27AK-7
CAS :<p>AK-7 is a brain-permeable SIRT2 inhibitor and to characterize its cholesterol-reducing properties in neuronal models with an IC50 of 15.5 μM.</p>Formule :C19H21BrN2O3SDegré de pureté :98.43% - 99.34%Couleur et forme :SolidMasse moléculaire :437.35Voxtalisib
CAS :<p>Voxtalisib (XL765) (SAR245409, XL765) is a dual inhibitor of mTOR/PI3K, mostly for p110γ with IC50 of 9 nM; also inhibits DNA-PK and mTOR. Phase 1/2.</p>Formule :C13H14N6ODegré de pureté :98.21% - 99.69%Couleur et forme :SolidMasse moléculaire :270.29Remetinostat
CAS :<p>Remetinostat (SHP-141), a hydroxamic acid-based inhibitor of histone deacetylase enzymes, is currently being developed for the treatment of cutaneous T-cell</p>Formule :C16H21NO6Degré de pureté :98.67%Couleur et forme :SolidMasse moléculaire :323.34Pixantrone hydrochloride
CAS :<p>Pixantrone hydrochloride is a topoisomerase II inhibitor and DNA intercalator with anti-tumor properties.</p>Formule :C17H20ClN5O2Couleur et forme :SolidMasse moléculaire :361.83PJ34
CAS :<p>PJ34 HCl is the hydrochloride salt of PJ34, which is a PARP inhibitor with EC50 of 20 nM and is equally potent to PARP1/2.</p>Formule :C17H17N3O2Degré de pureté :95.05% - 99.85%Couleur et forme :SolidMasse moléculaire :295.34Resminostat hydrochloride
CAS :<p>Resminostat hydrochloride (RAS2410 hydrochloride) is an effective inhibitor of HDAC1/HDAC3/HDAC6 (IC50: 42.5/50.1/71.8 nM), respectively, and shows less potent</p>Formule :C16H20ClN3O4SDegré de pureté :97.63% - 99.68%Couleur et forme :SolidMasse moléculaire :385.86L67
CAS :<p>L67 (DNA Ligase Inhibitor) is a competitive human DNA ligase inhibitor, inhibits DNA ligases I and III (IC50: 10 μM).</p>Formule :C16H14Br2N4O4Degré de pureté :98.34% - 99.56%Couleur et forme :SolidMasse moléculaire :486.11RK-287107
CAS :<p>RK-287107 is an effective and specific inhibitor of tankyrase (IC50s: 14.3 and 10.6 nM for tankyrase-1 and tankyrase-2, respectively).</p>Formule :C22H26F2N4O2Degré de pureté :99.64%Couleur et forme :SolidMasse moléculaire :416.46
