Altération de l'ADN/réparation de l'ADN
Les inhibiteurs de la réparation des dommages à l'ADN sont des composés qui interfèrent avec les processus impliqués dans la détection et la réparation des dommages à l'ADN. Ces inhibiteurs sont essentiels pour étudier les mécanismes de la stabilité génomique, de la mutagenèse et de la réponse aux dommages à l'ADN. Ils sont également importants dans la recherche sur le cancer, car de nombreuses tumeurs dépendent de voies spécifiques de réparation de l'ADN pour survivre. En inhibant ces voies, les inhibiteurs de la réparation des dommages à l'ADN peuvent améliorer l'efficacité de la chimiothérapie et de la radiothérapie. Chez CymitQuimica, nous offrons une large gamme d'inhibiteurs de haute qualité de la réparation des dommages à l'ADN pour soutenir vos recherches en biologie moléculaire, oncologie et pharmacologie.
Sous-catégories appartenant à la catégorie "Altération de l'ADN/réparation de l'ADN"
- ATM/ATR(71 produits)
- Alkylation de l'ADN(11 produits)
- Méthyltransférase de l’ADN(421 produits)
- Gyrase de l’ADN(11 produits)
- ADN-PK(51 produits)
- MTH1(1 produits)
- Antimétabolite nucléosidique/analogue(1.388 produits)
- Transcriptase inverse(43 produits)
- Sirtuine(88 produits)
- Télomérase(33 produits)
- Topoisomérase(136 produits)
Affichez 3 plus de sous-catégories
957 produits trouvés pour "Altération de l'ADN/réparation de l'ADN"
Trier par
Degré de pureté (%)
0
100
|
0
|
50
|
90
|
95
|
100
L67
CAS :<p>L67 (DNA Ligase Inhibitor) is a competitive human DNA ligase inhibitor, inhibits DNA ligases I and III (IC50: 10 μM).</p>Formule :C16H14Br2N4O4Degré de pureté :98.34% - 99.56%Couleur et forme :SolidMasse moléculaire :486.11Fluzoparib
CAS :<p>Fluzoparib (SHR3162) is a novel, potent, and orally available inhibitor of PARP, potentially for the treatment of solid tumours.</p>Formule :C22H16F4N6O2Degré de pureté :98.53% - 99.63%Couleur et forme :SolidMasse moléculaire :472.4SRT1720 hydrochloride
CAS :<p>SRT1720 hydrochloride (SRT1720 HCl) is a selective activator of SIRT1 (EC1.5: 0.16 μM) and shows less potent activities on SIRT2/SIRT3 (EC1.5s: 37 μM/300 μM).</p>Formule :C25H24ClN7OSDegré de pureté :98% - 99.93%Couleur et forme :SolidMasse moléculaire :506.22Pyridostatin TFA
CAS :<p>Pyridostatin Trifluoroacetate Salt is a G-quadruplexe stabilizer with Kd of 490 nM in a cell-free assay, which targets a series of proto-oncogenes including c-</p>Formule :C37H35F9N8O11Degré de pureté :97.09% - 99.84%Couleur et forme :SolidMasse moléculaire :938.71Suramin Sodium Salt
CAS :<p>Suramin Sodium Salt (BAY-205) is a polysulphonated naphthylurea with potential antineoplastic activity. Suramin blocks the binding of various growth factors.</p>Formule :C51H34N6Na6O23S6Degré de pureté :97.47% - 99.97%Couleur et forme :WhiteMasse moléculaire :1429.15Darglitazone Sodium
CAS :<p>Darglitazone Sodium, an oral PPAR-γ agonist, aids type II diabetes study by regulating glucose and lipids.</p>Formule :C23H21N2NaO4SCouleur et forme :SolidMasse moléculaire :444.48BGP-15
CAS :<p>BGP-15 (BGP-15 2HCl) is a PARP inhibitor with protecting effect after ischemia-reperfusion injury.</p>Formule :C14H24Cl2N4O2Degré de pureté :98.17% - 99.89%Couleur et forme :SolidMasse moléculaire :351.27Citarinostat
CAS :<p>ACY-241 (Citarinostat), a potent oral HDAC inhibitor, may induce tumor cell death and block growth by altering gene expression.</p>Formule :C24H26ClN5O3Degré de pureté :98.06% - 99.06%Couleur et forme :SolidMasse moléculaire :467.95Bisantrene
CAS :<p>Bisantrene, an anthracene derivative, targets DNA causing breaks and replication inhibition; it's like doxorubicin minus the cardiotoxicity.</p>Formule :C22H22N8Degré de pureté :96.07% - 98.57%Couleur et forme :SolidMasse moléculaire :398.46RHPS4
CAS :<p>RHPS4 (RHPS 4 methosulfate) is a potent inhibitor of Telomerase at submicromolar.</p>Formule :C22H17F2N2·CH3O4SDegré de pureté :99.72%Couleur et forme :SolidMasse moléculaire :458.48Thiacloprid
CAS :<p>Thiacloprid: insecticide targeting insect nAChRs, IC50 - Drosophila: 2.7 nM, Mouse α4β2 nAChRs: 860 nM.</p>Formule :C10H9ClN4SDegré de pureté :98.66% - 99.95%Couleur et forme :Yellowish Crystalline PowderMasse moléculaire :252.72Rabdosiin
CAS :<p>Rabdosiin ((+)-Rabdosiin) is a natural product, and has anti-allergic activity, anti-HIV activity and inhibition on DNA topoisomerase.</p>Formule :C36H30O16Degré de pureté :98.64% - 99.49%Couleur et forme :SolidMasse moléculaire :718.61PIK-75 hydrochloride
CAS :<p>PIK-75 hydrochloride (PIK-75 HCl) is a p110α inhibitor, isoform-specific mutants at Ser773, and potently inhibits DNA-PK with IC50 of 2 nM in cell-free assay.</p>Formule :C16H14BrN5O4S·HClDegré de pureté :97.82%Couleur et forme :SolidMasse moléculaire :488.74Pentamidine dihydrochloride
CAS :<p>Pentamidine dihydrochloride (MP-601205 dihydrochloride) is an aromatic diamidine agent with activity against a number of microorganisms including protozoa (</p>Formule :C19H26Cl2N4O2Degré de pureté :99.80%Couleur et forme :SolidMasse moléculaire :413.34JW 55
CAS :<p>JW 55 (JW55) is an effective and selective β-catenin signaling pathway inhibitor, works by inhibition of the PARP domain of tankyrase 1 and tankyrase 2 (TNKS1/2</p>Formule :C25H26N2O5Degré de pureté :99.31% - 99.76%Couleur et forme :SolidMasse moléculaire :434.48Tretazicar
CAS :<p>CB1954, an anticancer prodrug, turns into a potent alkylating agent when activated by NQO2 and EP-0152R.</p>Formule :C9H8N4O5Degré de pureté :99.41% - 99.7%Couleur et forme :SolidMasse moléculaire :252.18Coralyne chloride
CAS :<p>Coralyne chloride is a protoberberine with strong anticancer activity.</p>Formule :C22H22ClNO4Degré de pureté :98.88%Couleur et forme :SolidMasse moléculaire :399.87Adenine hemisulfate
CAS :<p>Adenine hemisulfate (Diadenine sulphate) is a sulfate salt form of adenine which is a purine derivative and a nucleobase with a variety of roles in biochemistry</p>Formule :(C5H5N5)·H2SO4Degré de pureté :99.48%Couleur et forme :White To Light Yellow Crystal PowderMasse moléculaire :368.33Selisistat S-enantiomer
CAS :<p>Selisistat S-enantiomer (EX-527 S-enantiomer) is an effective and specific SIRT1 inhibitor (IC50 = 98 nM) and shows >200-fold selectivity against SIRT2/3.</p>Formule :C13H13ClN2ODegré de pureté :99.86%Couleur et forme :SolidMasse moléculaire :248.71AZD 6482
CAS :<p>AZD 6482 (KIN-193) is a potent and selective inhibitor of p110β and PI3Kβ with IC50 values of 0.69nM and 10nM.Cost-effective and quality-assured.</p>Formule :C22H24N4O4Degré de pureté :99.79% - 99.95%Couleur et forme :SolidMasse moléculaire :408.45NPC 15199
CAS :<p>NPC 15199 (FMOC-L-Leucine) is an anti-inflammatory agent.</p>Formule :C21H23NO4Degré de pureté :99.93% - 99.94%Couleur et forme :White Crystalline PowderMasse moléculaire :353.41Genz-644282
CAS :<p>Genz-644282, a novel non-camptothecin topoisomerase I inhibitor for cancer treatment.</p>Formule :C22H21N3O5Degré de pureté :97.49%Couleur et forme :SolidMasse moléculaire :407.42Pentamidine
CAS :<p>Pentamidine is an antifungal and antiprotozoal agent, interacting directly with the pathogen genome by binding to AT-rich regions of duplex DNA and the minor</p>Formule :C19H24N4O2Degré de pureté :98.64% - 99.67%Couleur et forme :Crystallizes As Colorless Plates From Water SolidMasse moléculaire :340.42AG-494
CAS :<p>AG-494 (Tyrphostin B48) is an inhibitor of epidermal growth factor receptor kinase.</p>Formule :C16H12N2O3Degré de pureté :98.69%Couleur et forme :SolidMasse moléculaire :280.28TIQ-A
CAS :<p>TIQ-A blocks PARP1 to prevent excessive DNA damage response, implicated in ischemia, asthma, and atherosclerosis.</p>Formule :C11H7NOSDegré de pureté :99.75%Couleur et forme :SolidMasse moléculaire :201.24AZD-2461
CAS :<p>AZD2461 is a novel PARP inhibitor.</p>Formule :C22H22FN3O3Degré de pureté :98% - 99.87%Couleur et forme :SolidMasse moléculaire :395.43Clofibrate
CAS :<p>Clofibrate (Clofibrato) is an aryloxyisobutyric acid derivate with antihyperlipidemic activity.</p>Formule :C12H15ClO3Degré de pureté :98.77%Couleur et forme :Oil LiquidMasse moléculaire :242.70Pyridostatin
CAS :<p>Pyridostatin (RR82) is a synthetic small-molecule stabilizer of G-quadruplexes, a secondary structure of DNA that usually exists in the end of the chromosome or</p>Formule :C31H32N8O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :596.64TMPyP4 tosylate
CAS :<p>TMPyP4 tosylate (TMP 1363) is a quadruplex-specific ligand and is a telomerase inhibitor with antitumor effects in osteosarcoma cell lines.</p>Formule :C72H66N8O12S4Degré de pureté :98.61% - 99.85%Couleur et forme :SolidMasse moléculaire :1363.6UPF 1069
CAS :<p>UPF 1069 is a specific PARP2 inhibitor ( IC50: 0.3 μM). It is ~27-fold selective against PARP1.</p>Formule :C17H13NO3Degré de pureté :98.80% - 99.88%Couleur et forme :SolidMasse moléculaire :279.29KU-57788
CAS :<p>NU7441 (KU-57788 (NU7441)) is a highly effective and specific DNA-PK inhibitor (IC50: 14 nM).</p>Formule :C25H19NO3SDegré de pureté :98% - >99.99%Couleur et forme :SolidMasse moléculaire :413.49EDO-S101
CAS :<p>EDO-S101 (Tinostamustine) is a pan HDAC inhibitor with IC50 values of 9, 9 and 25 nM for HDAC1, HDAC2 and HDAC3 , respectively.</p>Formule :C19H28Cl2N4O2Degré de pureté :98.02% - 99.44%Couleur et forme :SolidMasse moléculaire :415.36PI3K-IN-1
CAS :<p>PI3K-IN-1 (Voxtalisib Analogue) is a dual inhibitor of mTOR/PI3K, mostly for p110γ , also inhibits DNA-PK and mTOR.</p>Formule :C31H29N5O6SDegré de pureté :97.03% - 98%Couleur et forme :SolidMasse moléculaire :599.66RK-287107
CAS :<p>RK-287107 is an effective and specific inhibitor of tankyrase (IC50s: 14.3 and 10.6 nM for tankyrase-1 and tankyrase-2, respectively).</p>Formule :C22H26F2N4O2Degré de pureté :99.64%Couleur et forme :SolidMasse moléculaire :416.46SCR130
CAS :<p>SCR130 (1,7,9-Triazaspiro[4.5]dec-1-ene-6,10-dione, 2,4-bis(4-chlorophenyl)-8-thioxo-) 是基于 SCR7 的 DNA 非同源末端连接抑制剂，可诱导细胞凋亡并，具有抗癌活性。 它特异性依赖连接酶 IV，抑制 DNA 的末端连接。</p>Formule :C19H13Cl2N3O2SDegré de pureté :98.9%Couleur et forme :SolidMasse moléculaire :418.3PARP1-IN-5 dihydrochloride
CAS :<p>PARP1-IN-5 dihydrochloride: oral, potent PARP-1 inhibitor (IC50=14.7 nM), for cancer research.</p>Formule :C25H26Cl2N2O5SDegré de pureté :98.01%Couleur et forme :SolidMasse moléculaire :537.46OUL35
CAS :<p>OUL35 (NSC-39047) is a selective PARP-10 inhibitor, and small-molecule ARTD10 inhibitor. OUL35 has been shown to rescue cells from ARTD10-induced cell death.</p>Formule :C14H12N2O3Degré de pureté :99.2%Couleur et forme :SolidMasse moléculaire :256.26Furegrelate
CAS :<p>FUREGRELATE, a thromboxane A2 (TxA2) synthase inhibitor, blunts the development of pulmonary arterial hypertension in neonatal piglets.</p>Formule :C15H11NO3Degré de pureté :99.71%Couleur et forme :SolidMasse moléculaire :253.25AZ32
CAS :<p>AZ32 is an orally bioavailable and blood-brain barrier-penetrating ATM inhibitor with an IC50 of <6.2 nM for ATM enzyme, and an IC50 of 0.31 μM for ATM in cell.</p>Formule :C20H16N4ODegré de pureté :98.68% - 99.68%Couleur et forme :SolidMasse moléculaire :328.37AZ9482
CAS :<p>AZ9482, a potent PARP inhibitor with 2-piperazinyl-3-cyano-pyridine linkage, causes centrosome declustering in HeLa cells with an EC50 < 18 nM.</p>Formule :C26H22N6O2Degré de pureté :99.18% - 99.86%Couleur et forme :SolidMasse moléculaire :450.49DR2313
CAS :<p>DR2313 is a competitive inhibitor of poly(ADP-ribose) polymerase (IC50: 0.20 and 0.24 μM for PARP-1 and PARP-2 respectively). It also has neuroprotective.</p>Formule :C8H10N2OSDegré de pureté :98.65%Couleur et forme :SolidMasse moléculaire :182.24VAL-083
CAS :<p>VAL-083 (Dianhydrogalactitol) is an alkylating compound that creates N7 methylation on DNA. It also has antitumor activity.</p>Formule :C6H10O4Degré de pureté :97.94%Couleur et forme :SolidMasse moléculaire :146.14E7449
CAS :<p>E7449 is a potent inhibitor of PARP1, PARP2, TNKS1, and TNKS2 with IC50s of 2, 1, ~50, and ~50 nM respectively.</p>Formule :C18H15N5ODegré de pureté :97.13%Couleur et forme :SolidMasse moléculaire :317.34Pixantrone hydrochloride
CAS :<p>Pixantrone hydrochloride is a topoisomerase II inhibitor and DNA intercalator with anti-tumor properties.</p>Formule :C17H20ClN5O2Couleur et forme :SolidMasse moléculaire :361.83Methotrexate disodium
CAS :<p>Methotrexate disodium is an tetrahydrofolate dehydrogenase inhibitor</p>Formule :C20H20N8Na2O5Degré de pureté :99.77% - 99.96%Couleur et forme :SolidMasse moléculaire :498.4NKL 22
CAS :<p>NKL 22 (Histone Deacetylase Inhibitor IV) is an effective Histone Deacetylase Inhibitor.</p>Formule :C19H23N3O2Degré de pureté :96.16% - 96.24%Couleur et forme :SolidMasse moléculaire :325.4Carmustine
CAS :<p>Carmustine (bis-chloroethylnitrosourea) is a cell-cycle phase nonspecific alkylating antineoplastic agent.</p>Formule :C5H9Cl2N3O2Degré de pureté :98% - 99.91%Couleur et forme :Light Yellow Powder Physical Description Orange-Yellow Solid (Ntp 1992)Masse moléculaire :214.05AGK7
CAS :<p>AGK7 is an AGK2 control; it's a less selective SIRT2 inhibitor, with IC50s >5 μM for SIRT3, and >50 μM for SIRT1/2.</p>Formule :C23H13Cl2N3O2Degré de pureté :98.31%Couleur et forme :SolidMasse moléculaire :434.27AZD-7648
CAS :<p>AZD-7648 is an inhibitor of DNA-dependent protein kinase (DNA-PK) with the IC50 of 0.63 nM in an enzyme assay,has anti-tumor activity.</p>Formule :C18H20N8O2Degré de pureté :99.03% - 99.85%Couleur et forme :SolidMasse moléculaire :380.4Xanthosine 5'-monophosphate sodium salt
CAS :<p>Xanthosine 5'-monophosphate sodium salt (L-XMP Sodium) is an intermediate in purine metabolism.</p>Formule :C10H11N4Na2O9PDegré de pureté :99% - 99.77%Couleur et forme :SolidMasse moléculaire :408.17Pirarubicin
CAS :<p>Pirarubicin (Theprubicin), an anthracycline antibiotic, inhibits DNA/RNA synthesis and is used as an antineoplastic.</p>Formule :C32H37NO12Degré de pureté :97.80% - 99.15%Couleur et forme :Red Crystalline PowderMasse moléculaire :627.64Levofloxacin hydrochloride
CAS :<p>Levofloxacin is a broad-spectrum, third-generation fluoroquinolone antibiotic and optically active L-isomer of ofloxacin with antibacterial activity.</p>Formule :C18H21ClFN3O4Degré de pureté :99.78% - 99.98%Couleur et forme :SolidMasse moléculaire :397.89-Hydroxycamptothecin
CAS :<p>9-Hydroxycampothecin is a camptothecin derivative with anticancer activity.</p>Formule :C20H16N2O5Degré de pureté :98.28%Couleur et forme :SolidMasse moléculaire :364.35Ganciclovir sodium
CAS :<p>Ganciclovir sodium, a sodium salt with anti-CMV and HSV-1 antiviral properties.</p>Formule :C9H13N5NaO4Degré de pureté :99.93%Couleur et forme :SolidMasse moléculaire :278.22Silver sulfadiazine
CAS :<p>Silver sulfadiazine (Dermazin) is a sulfonamide-based topical agent with antibacterial and antifungal activity.</p>Formule :C10H9AgN4O2SDegré de pureté :99.04% - 99.58%Couleur et forme :SolidMasse moléculaire :357.14Deoxycytidine triphosphate
CAS :<p>dCTP is a nucleotide used in DNA synthesis, PCR, cDNA creation, and sequencing.</p>Formule :C9H16N3O13P3Degré de pureté :99.68%Couleur et forme :SolidMasse moléculaire :467.16AZ6102
CAS :<p>AZ6102: Potent TNKS1/2 inhibitor, 100x selective over PARPs, IC50 = 5 nM in DLD-1 Wnt pathway.</p>Formule :C25H28N6ODegré de pureté :97.98% - 99.91%Couleur et forme :SolidMasse moléculaire :428.53MK-4827 Racemate
CAS :<p>MK-4827 Racemate (Niraparib Racemate) is a selective PARP1 and PARP2 inhibitor with IC50s of 3.8 nM and 2.1 nM, respectively, over 330-fold selectivity for</p>Formule :C19H20N4ODegré de pureté :99.86%Couleur et forme :SolidMasse moléculaire :320.39LMK-235
CAS :<p>LMK-235 is a potent HDAC inhibitor, and is used in cancer research.</p>Formule :C15H22N2O4Degré de pureté :98.18% - 99.68%Couleur et forme :SolidMasse moléculaire :294.35Altretamine hydrochloride
CAS :<p>Altretamine hydrochloride is an alkylating antineoplastic agent.</p>Formule :C9H19ClN6Couleur et forme :SolidMasse moléculaire :246.74Ensulizole
CAS :<p>Ensulizole, a water-soluble UV absorber, damages DNA by generating ROS under UV light, and absorbs UVB and some UVA.</p>Formule :C13H10N2O3SDegré de pureté :99.79%Couleur et forme :White To Pale Beige Solid PowderMasse moléculaire :274.30EIDD-1931
CAS :<p>EIDD-1931 (Beta-d-N4-hydroxycytidine) is a ribonucleoside analog with antiviral activity. It inhibits replication of SARS-CoV, MERS-CoV, and SARS-CoV-2.</p>Formule :C9H13N3O6Degré de pureté :99.14% - 99.73%Couleur et forme :SolidMasse moléculaire :259.22CXD101
CAS :<p>CXD101 is a novel class I-selective HDACi (HDAC1 (IC50 : 63nM), HDAC2 (IC50 :570nM), HDAC3 (IC50 :550nM)). CXD101(CXD-101) has no activity against HDAC class II</p>Formule :C24H29N5ODegré de pureté :99.82%Couleur et forme :SolidMasse moléculaire :403.522',3',5'-triacetyl-5-Azacytidine
CAS :<p>2',3',5'-triacetyl-5-Azacytidine (Nsc291930) is a prodrug form of 5-azacytidine that may be rapidly absorbed orally.</p>Formule :C14H18N4O8Degré de pureté :98.34%Couleur et forme :SolidMasse moléculaire :370.31AG14361
CAS :<p>AG14361 is an effective inhibitor of PARP1 (Ki<5 nM).</p>Formule :C19H20N4ODegré de pureté :98.7% - 99.93%Couleur et forme :SolidMasse moléculaire :320.391-Oleoyl lysophosphatidic acid sodium
CAS :<p>1-Oleoyl lysophosphatidic acid sodium (1-Oleoyl lysophosphatidic acid sodium salt) salt is an Endogenous agonist of LPA1 and LPA2</p>Formule :C21H40O7P·NaDegré de pureté :98.75% - 99.24%Couleur et forme :SolidMasse moléculaire :458.51GW9662
CAS :<p>GW9662 (TIMTEC-BB SBB006523) is a PPARγ antagonist (IC50=3.3 nM) with selectivity. GW9662 has anti-tumor effect. High-Quality, Low-Cost!</p>Formule :C13H9ClN2O3Degré de pureté :98% - 99.95%Couleur et forme :Off-White SolidMasse moléculaire :276.681,4-Naphthoquinone
CAS :<p>1,4-Naphthoquinone used as inhibitor for monoamine oxidase, DNA topoisomerase, and acetyltransferase.</p>Formule :C10H6O2Degré de pureté :99.24% - 99.56%Couleur et forme :SolidMasse moléculaire :158.15M344
CAS :<p>M344 (Histone Deacetylase Inhibitor III) is a potent HDAC inhibitor with IC50 of 100 nM and able to induce cell differentiation.</p>Formule :C16H25N3O3Degré de pureté :98.18%Couleur et forme :SolidMasse moléculaire :307.39SRT 1720
CAS :<p>SRT 1720 is a selective activator of human SIRT1 (EC1.5: 0.16 μM) and is >230-fold less potent for SIRT2 and SIRT3.</p>Formule :C25H23N7OSDegré de pureté :98.84%Couleur et forme :SolidMasse moléculaire :469.56CM-579 trihydrochloride
<p>CM-579 trihydrochloride: reversible G9a/DNMT inhibitor with IC50s 16 nM (G9a) & 32 nM (DNMT); potent against various cancer cells.</p>Formule :C29H43Cl3N4O3Couleur et forme :SolidMasse moléculaire :602.04NU 7026
CAS :<p>NU 7026 (DNA-PK Inhibitor II) is an effective DNA-PK inhibitor (IC50: 0.23 μM, in cell-free assays), 60-fold selective for DNA-PK than PI3K and no inhibition</p>Formule :C17H15NO3Degré de pureté :99.51% - >99.99%Couleur et forme :SolidMasse moléculaire :281.31NU1025
CAS :<p>NU1025 (NSC-696807) is a potent PARP inhibitor with IC50 of 400 nM.</p>Formule :C9H8N2O2Degré de pureté :99.86%Couleur et forme :SolidMasse moléculaire :176.17Gatifloxacin hydrochloride
CAS :<p>Gatifloxacin hydrochloride, a fourth-gen fluoroquinolone antibiotic, blocks bacterial DNA rotase and topoisomerase IV.</p>Formule :C19H23ClFN3O4Degré de pureté :99.85% - 99.89%Couleur et forme :SolidMasse moléculaire :411.86SirReal2
CAS :<p>SirReal2 is a potent and selective Sirt2 inhibitor with IC50 of 140 nM.</p>Formule :C22H20N4OS2Degré de pureté :98.96% - 99.75%Couleur et forme :SolidMasse moléculaire :420.551-Hydroxyanthraquinone
CAS :<p>1-Hydroxyanthraquinone is an anthraquinone that has been found in Morinda officinalis and has genotoxic and carcinogenic activities.</p>Formule :C14H8O3Degré de pureté :99.56%Couleur et forme :Orange Red Needles Red-Orange To Fine Yellow CrystalsMasse moléculaire :224.21ML216
CAS :<p>ML216 (CID-49852229) inhibits BLM helicase (IC50: 1.8 μM), 28-fold selective over RECQ1, RECQ5, and UvrD (IC50s > 50 μM).</p>Formule :C15H9F4N5OSDegré de pureté :98.12%Couleur et forme :SolidMasse moléculaire :383.32NMS-P118
CAS :<p>NMS-P118 is a potent, selective and orally available Inhibitor of PARP-1 for cancer therapy.</p>Formule :C20H24F3N3O2Degré de pureté :98.79%Couleur et forme :SolidMasse moléculaire :395.42Zebularine
CAS :<p>Zebularine (4-Deoxyuridine) is a DNA methylation inhibitor.</p>Formule :C9H12N2O5Degré de pureté :99.04% - >99.99%Couleur et forme :SolidMasse moléculaire :228.2Thymidine
CAS :<p>Thymidine (DThyd) is a cell synchronizing agent and a precursor of deoxyribonucleic acid. Thymidine inhibits DNA synthesis. Cost-effective and quality-assured.</p>Formule :C10H14N2O5Degré de pureté :99.64% - 99.86%Couleur et forme :White To Off-White Solid CrystallineMasse moléculaire :242.23Palifosfamide tromethamine
CAS :<p>Palifosfamide, a less toxic ifosfamide metabolite, is a DNA-alkylating anticancer agent.</p>Formule :C8H22Cl2N3O5PCouleur et forme :SolidMasse moléculaire :342.16Azemiglitazone
CAS :<p>Azemiglitazone (MSDC 0602) is an insulin sensitizer potentially for the treatment of diabetes.</p>Formule :C19H17NO5SDegré de pureté :98.29% - 99.6%Couleur et forme :SolidMasse moléculaire :371.41UBCS039
CAS :<p>UBCS039 is the first synthetic Sirt6 activator(EC50 : 38 μM)</p>Formule :C16H13N3Degré de pureté :98.31%Couleur et forme :SolidMasse moléculaire :247.29SW-100
CAS :<p>SW-100 is a potent HDAC6 inhibitor with 2.3 nM IC50, highly selective (>1000-fold), can cross blood-brain-barrier.</p>Formule :C17H17ClN2O2Degré de pureté :98.34% - 98.47%Couleur et forme :SolidMasse moléculaire :316.78GSK3685032
CAS :<p>GSK3685032 is a non-covalent and selective DNMT1 inhibitor(IC50 = 36 nM).</p>Formule :C22H24N6OSDegré de pureté :98.56% - 99.49%Couleur et forme :SolidMasse moléculaire :420.53L-778123 hydrochloride
CAS :<p>The L-778123 hydrochloride is an inhibitor of FPTase (IC50: 2 nM) and GGPTase-I (IC50: 98 nM) in enzyme inhibition determination.</p>Formule :C22H21Cl2N5ODegré de pureté :93.93% - 98.51%Couleur et forme :SolidMasse moléculaire :442.34Indotecan
CAS :<p>Indotecan (LMP-400) is an effective inhibitor of topoisomerase 1(Top1) (IC50: 300, 1200, 560 nM for P388, HCT116, MCF-7 cell lines, respectively).</p>Formule :C26H26N2O7Degré de pureté :97% - 98%Couleur et forme :SolidMasse moléculaire :478.49Hinokitiol
CAS :<p>Hinokitiol prevents UVB-caused cell death, boosts antioxidant activity, and hinders breast cancer growth.</p>Formule :C10H12O2Degré de pureté :99.49% - 99.67%Couleur et forme :SolidMasse moléculaire :164.2PI-3065
CAS :<p>PI-3065 is a novel potent and selective PI3K p110δ inhibitor.</p>Formule :C27H31FN6OSDegré de pureté :99.84% - ≥95%Couleur et forme :SolidMasse moléculaire :506.64Senaparib
CAS :<p>Senaparib (IMP4297) is a novel highly potent and selective oral PARP1/2 inhibitor with strong antitumor activity.</p>Formule :C24H20F2N6O3Degré de pureté :99.8%Couleur et forme :SolidMasse moléculaire :478.45Rubitecan
CAS :<p>Rubitecan: a semisynthetic DNA topoisomerase I inhibitor with antitumor and antiviral effects.</p>Formule :C20H15N3O6Degré de pureté :97.54%Couleur et forme :Yellow Amorphous PowderMasse moléculaire :393.35Prulifloxacin
CAS :<p>Prulifloxacin (NM441) is a broad-spectrum fluoroquinolone that inhibits bacterial DNA synthesis by blocking topoisomerase II and IV.</p>Formule :C21H20FN3O6SDegré de pureté :99.47%Couleur et forme :Yellow Or Slightly Yellow PowerMasse moléculaire :461.46Ceralasertib
CAS :<p>Ceralasertib (AZD6738) is an ATR kinase inhibitor (IC50=1 nM) with selective and oral activity. Ceralasertib has antitumor activity. Cost effective and quality assured.</p>Formule :C20H24N6O2SDegré de pureté :98% - 99.99%Couleur et forme :SolidMasse moléculaire :412.51VE-821
CAS :<p>VE-821 (ATR Inhibitor IV) is a selective ATP competitive inhibitor of ATR( Ki/IC50: 13/26 nM in cell-free assays).</p>Formule :C18H16N4O3SDegré de pureté :97.19% - 99.97%Couleur et forme :SolidMasse moléculaire :368.41Cycloastragenol
CAS :<p>Cycloastragenol, a saponin from Astragalus, could be a new depression treatment.</p>Formule :C30H50O5Degré de pureté :99.85% - 99.92%Couleur et forme :SolidMasse moléculaire :490.71γ-Oryzanol
CAS :<p>γ-Oryzanol (Gamma-Oryzanol) is a natural nutrient extract isolated from rice bran oil that contains a mixture of sterols and ferulic acids, which may aid in the</p>Formule :C40H58O4Degré de pureté :mixture - mixtureCouleur et forme :White Or White Crystalline Powder OdourlessMasse moléculaire :602.9Thiomyristoyl
CAS :<p>Thiomyristoyl is an effective and selective SIRT2 inhibitor (IC50: 28 nM). It inhibits SIRT1 (IC50: 98 μM) but no effect on SIRT3 even at 200 μM.</p>Formule :C34H51N3O3SDegré de pureté :99.16%Couleur et forme :SolidMasse moléculaire :581.85MN-64
CAS :<p>MN-64 is a tankyrases inhibitor, showed 6 nM potency against tankyrase 1, isoenzyme selectivity, and Wnt signaling inhibition.</p>Formule :C18H16O2Degré de pureté :99.5% - 99.93%Couleur et forme :SolidMasse moléculaire :264.32Pixantrone
CAS :<p>Pixantrone has anti-tumor activity that is a DNA intercalator and topoisomerase II inhibitor.</p>Formule :C17H19N5O2Couleur et forme :SolidMasse moléculaire :325.37BMH-21
CAS :<p>BMH-21, a small molecule DNA intercalator, binds ribosomal DNA and inhibits RNA polymerase I (Pol I) transcription and not affects phosphorylation of H2AX.</p>Formule :C21H20N4O2Degré de pureté :99.47% - 99.84%Couleur et forme :SolidMasse moléculaire :360.41
