Antimétabolite nucléosidique/analogue
Les antimétabolites et analogues des nucléosides sont des composés qui imitent les nucléosides naturels et sont incorporés dans l'ADN lors de la réplication, entraînant la terminaison de la chaîne ou l'inhibition de la synthèse de l'ADN. Ces composés sont largement utilisés comme agents chimiothérapeutiques dans le traitement du cancer et des infections virales. En perturbant la synthèse de l'ADN, les analogues des nucléosides induisent l'arrêt du cycle cellulaire et l'apoptose. Chez CymitQuimica, nous offrons une large gamme d'antimétabolites et d'analogues de nucléosides de haute qualité pour soutenir vos recherches sur le traitement du cancer, la thérapie antivirale et la réplication de l'ADN.
341 produits trouvés pour "Antimétabolite nucléosidique/analogue".
Trier par
Degré de pureté (%)
0
100
|
0
|
50
|
90
|
95
|
100
2'-O,4'-C-Methyleneadenosine 5'-monophosphate triethylammonium
2’-O,4’-C-Methyleneadenosine 5’-monophosphate (triethylammonium), a purine nucleoside analog, exhibits wide-ranging antitumor activity against indolent lymphoidFormule :C23H46N7O7PCouleur et forme :SolidMasse moléculaire :563.63Uridine-5-oxo-acetyl-(9-fluorenylmethyl) ester
Uridine analogue with antitumor effects; inhibits DNA synthesis, induces apoptosis in lymphoid cancers.Formule :C24H24N2O9Couleur et forme :SolidMasse moléculaire :484.46N1-Methyl-3'-O-(2-methoxyethyl) adenosine
N1-Methyl-3’-O-(2-methoxyethyl) adenosine, a purine nucleoside analog, exhibits broad antitumor activity against indolent lymphoid malignancies.Formule :C14H21N5O5Couleur et forme :SolidMasse moléculaire :339.352'-Deoxy-2'-fluoro-N3-[(pyrid-4-yl)methyl]uridine
2’-Deoxy-2’-fluoro-N3-[(pyrid-4-yl)methyl]uridine is a purine nucleoside analog widely known for its antitumor activity, particularly against indolent lymphoidFormule :C15H16FN3O5Couleur et forme :SolidMasse moléculaire :337.35'-O-Benzoyl-3'-O-(4-methoxybenzyl)-2'-O,4'-C-methyleneuridine
5’-O-Benzoyl-3’-O-(4-methoxybenzyl)-2’-O,4’-C-methyleneuridine is a purine nucleoside analog with broad antitumor activity, primarily targeting indolentFormule :C25H24N2O8Couleur et forme :SolidMasse moléculaire :480.472'-Deoxy-2'-fluoro-N3-[(pyrid-2-yl)methyl]uridine
2’-Deoxy-2’-fluoro-N3-[(pyrid-2-yl)methyl]uridine, a uridine analogue, exhibits potential for antiepileptic applications.Formule :C15H16FN3O5Couleur et forme :SolidMasse moléculaire :337.31-(β-D-Xylofuranosyl)-N6-Isopentenyladenine
1-(β-D-Xylofuranosyl)-N6-Isopentenyladenine is an adenosine analog.Formule :C15H21N5O4Couleur et forme :SolidMasse moléculaire :335.366-Amino-4-methoxy-2-(β-D-ribofuranosyl)-2H-pyrazolo[3,4-d]pyrimidine
6-Amino-4-methoxy-2-(β-D-ribofuranosyl)-2H-pyrazolo[3,4-d]pyrimidine, a purine nucleoside analogue, exhibits widespread antitumor efficacy, particularly againstFormule :C11H17N5O5Couleur et forme :SolidMasse moléculaire :299.28Rev dC(Bz)-5'-amidite
Rev dC(Bz)-5'-amidite, a purine nucleoside analog with antitumor effects, inhibits DNA synthesis and induces apoptosis in lymphoid cancers.Formule :C46H52N5O8PCouleur et forme :SolidMasse moléculaire :833.919-(5(R)-C-Methyl-2,3,5-tri-O-benzoyl-D-ribofuranosyl)-6-chloropurine
9-(5(R)-C-Methyl-2,3,5-tri-O-benzoyl-D-ribofuranosyl)-6-chloropurine: A purine analog with antitumor effects, inhibiting DNA synthesis and inducing apoptosis.Formule :C32H25ClN4O7Couleur et forme :SolidMasse moléculaire :613.023'-O-(4,4'-Dimethoxy trityl)-2'-O-(2-methoxyethyl)-5-methyluridine
3’-O-(4,4’-Dimethoxy trityl)-2’-O-(2-methoxyethyl)-5-methyluridine, a purine nucleoside analog, exhibits extensive antitumor properties against indolentFormule :C34H38N2O9Couleur et forme :SolidMasse moléculaire :618.67Adenosine Dialdehyde (ADOX)
CAS :Adenosine Dialdehyde, a purine analogue, inhibits SAHH (Ki=3.3 nM), and shows strong anti-tumor effects in vivo.Formule :C10H11N5O4Degré de pureté :95%Couleur et forme :SolidMasse moléculaire :265.23Ref: TM-T22231
5mg52,00€1mL*10mM (DMSO)57,00€10mg66,00€25mg88,00€50mg155,00€100mg225,00€200mg335,00€500mg565,00€2'-O-Methyl-5-methyluridine 5'-triphosphate triethylammonium
2’-O-Methyl-5-methyluridine 5’-triphosphate (triethylammonium), a thymidine analog, exhibits insertional activity in replicated DNA.Formule :C29H64N5O15P3Couleur et forme :SolidMasse moléculaire :815.765'-O-DMTr-2',2'-difluoro-dC(Bz)-methyl phosphonamidite
5’-O-DMTr-2’,2’-difluoro-dC(Bz)-methyl phosphonamidite is a purine nucleoside analog with extensive antitumor activity against indolent lymphoid malignancies.Formule :C44H49F2N4O7PCouleur et forme :SolidMasse moléculaire :814.856-O-Methyl-2'-O-methylinosine
6-O-Methyl-2’-O-methylinosine is a purine nucleoside analog known for its broad antitumor activity, particularly against indolent lymphoid malignancies.Formule :C12H16N4O5Couleur et forme :SolidMasse moléculaire :296.283'-O-DMT-N2-isobutyryl-2'-O-(2-methoxyethyl)guanosine
3’-O-DMT-N2-isobutyryl-2’-O-(2-methoxyethyl)guanosine, a purine nucleoside analog, exhibits broad antitumor activity particularly against indolent lymphoidFormule :C38H43N5O9Couleur et forme :SolidMasse moléculaire :713.78N1-Methyl-2'-β-C-methyl inosine
N1-Methyl-2’-beta-C-methyl inosine, a purine nucleoside analog, exhibits broad antitumor activity against indolent lymphoid malignancies through mechanisms thatFormule :C12H16N4O5Couleur et forme :SolidMasse moléculaire :296.28N1-Methyl-2'-O-(2-methoxyethyl) guanosine
N1-Methyl-2’-O-(2-methoxyethyl) guanosine, a purine nucleoside analog, exhibits broad antitumor activity against indolent lymphoid malignancies.Formule :C14H21N5O6Couleur et forme :SolidMasse moléculaire :355.358-Chloro-2'-deoxy-2'-fluoro-arabino adenosine
8-Chloro-2’-deoxy-2’-fluoro-arabino adenosine, a purine nucleoside analog, demonstrates broad antitumor activity against indolent lymphoid malignancies.Formule :C10H11ClFN5O3Couleur et forme :SolidMasse moléculaire :303.682-(3-Methyln-propylidene hydrazino) adenosine
2-(3-Methyln-propylidene hydrazino) adenosine: a purine analog with antitumor properties, inhibits DNA synthesis, induces apoptosis.Formule :C15H23N7O4Couleur et forme :SolidMasse moléculaire :365.393,5'-Bis(O-t-butyldimethylsilyl)-2'-O-methyl-5-methyl cytidine
3,5’-Bis(O-t-butyldimethylsilyl)-2’-O-methyl-5-methyl cytidine, a cytidine analog, inhibits DNA methyltransferases (e.g., Zebularine), exhibiting potential antiFormule :C23H45N3O5Si2Couleur et forme :SolidMasse moléculaire :499.795'-O-DMTr-2'-O-MOE inosine 3'-P-methyl phosphonamidite
5’-O-DMTr-2’-O-MOE inosine 3’-P-methyl phosphonamidite, a purine nucleoside analog, exhibits extensive antitumor activity specific to indolent lymphoidFormule :C41H52N5O8PCouleur et forme :SolidMasse moléculaire :773.85N1-(2-Methyl)propyl pseudouridine
N1-(2-Methyl)propyl pseudouridine, a purine analog, targets lymphoid cancer by inhibiting DNA synthesis and inducing apoptosis.Formule :C13H20N2O6Couleur et forme :SolidMasse moléculaire :300.31Isocytosine
CAS :Isocytosine ,with CAS No. 108-53-2, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Isocytosine provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.Formule :C4H5N3OCouleur et forme :White To Off-White SolidMasse moléculaire :111.12'-Deoxy-2'-fluoro-N3-(n-dodecyl)uridine
2’-Deoxy-2’-fluoro-N3-(n-dodecyl)uridine, a purine nucleoside analog, exhibits broad antitumor activity, particularly against indolent lymphoid malignancies.Formule :C21H35FN2O5Couleur et forme :SolidMasse moléculaire :414.51N1-Methyl-2'-O-(2-methoxyethyl) adenosine
N1-Methyl-2’-O-(2-methoxyethyl) adenosine, a purine nucleoside analog, exhibits broad antitumor effects, particularly against indolent lymphoid malignancies.Formule :C14H21N5O5Couleur et forme :SolidMasse moléculaire :339.355-Aza-xylo-cytidine
5-Aza-xylo-cytidine, a purine analog with antitumor effects, inhibits DNA synthesis and induces apoptosis in lymphoid cancers.Formule :C8H12N4O5Couleur et forme :SolidMasse moléculaire :244.23'-β-C-Methyl-2-thiouridine
3’-β-C-Methyl-2-thiouridine, a purine nucleoside analog, exhibits extensive antitumor activity, particularly against indolent lymphoid malignancies.Formule :C10H14N2O5SCouleur et forme :SolidMasse moléculaire :274.29N4-Benzoyl-2'-deoxy-2'-fluoro-β-D-arabinocytidine
N4-Benzoyl-2’-deoxy-2’-fluoro-β-D-arabinocytidine, a purine nucleoside analog, exhibits widespread antitumor activity, particularly against indolent lymphoidFormule :C16H16FN3O5Couleur et forme :SolidMasse moléculaire :349.31N4-Benzoyl-3'-O-DMT-2'-O-(2-methoxyethyl)-5-methylcytidine
N4-Benzoyl-3'-O-DMT cytidine analog inhibits DNA methyltransferases like Zebularine.Formule :C41H43N3O9Couleur et forme :SolidMasse moléculaire :721.79Py-MAA-Val-Cit-PAB-DX8951
CAS :Py-MAA-Val-Cit-PAB-DX8951, a purine toxin, serves as an intermediate in the synthesis of antibody-drug conjugates [1].Formule :C57H66FN11O13SCouleur et forme :SolidMasse moléculaire :1164.262-(P-Cyanophenyl methylidene hydrazino) adenosine
2-(P-Cyanophenyl methylidene hydrazino) adenosine: a purine analog with antitumor effects via DNA synthesis inhibition and apoptosis.Formule :C18H18N8O4Couleur et forme :SolidMasse moléculaire :410.39DMT-dG(ib) Phosphoramidite
CAS :DMT-dG(ib) Phosphoramidite can be used to synthesize DNA.Formule :C44H54N7O8PDegré de pureté :99.21%Couleur et forme :SolidMasse moléculaire :839.92N6-Benzoyl-3'-O-DMT-2'-O-(2-methoxyethyl) adenosine
N6-Benzoyl-3'-O-DMT-adenosine is a purine analog with antitumor effects by hindering DNA synthesis and inducing apoptosis.Formule :C41H41N5O8Couleur et forme :SolidMasse moléculaire :731.795'(R)-C-Methyl-5-fluorouridine
5’(R)-C-Methyl-5-fluorouridine, a uridine analogue, possesses potential antiepileptic properties.Formule :C10H13FN2O6Couleur et forme :SolidMasse moléculaire :276.225'-O-(4,4'-Dimethoxy trityl)-2'-O-(2-methoxyethyl) inosine
5’-O-(4,4’-Dimethoxytrityl)-2’-O-(2-methoxyethyl)inosine is a purine nucleoside analog with broad antitumor activity, primarily targeting indolent lymphoidFormule :C34H36N4O8Couleur et forme :SolidMasse moléculaire :628.67N6-Methyl-2'-β-C-ethynyl adenosine
N6-Methyl-2’-beta-C-ethynyl adenosine is a purine nucleoside analog.Formule :C13H15N5O4Couleur et forme :SolidMasse moléculaire :305.295-(2-Hydroxyethyl)-2',3'-di-O-toluoyl-2'-deoxyuridine
5-(2-Hydroxyethyl)-2',3'-di-O-toluoyl-2'-deoxyuridine, a purine nucleoside analog, exhibits widespread antitumor activity specifically against indolent lymphoidFormule :C27H28N2O8Couleur et forme :SolidMasse moléculaire :508.522-Amino-6-O-methyl-2'-O-methyl purine riboside
2-Amino-6-O-methyl-2’-O-methyl purine riboside, a purine nucleoside analog, exhibits broad antitumor activity, particularly against indolent lymphoidFormule :C12H17N5O5Couleur et forme :SolidMasse moléculaire :311.296-Methoxypurine-9-β-D-5'(R)-C-methylriboside
6-Methoxypurine-9-β-D-5’(R)-C-methylriboside, an analog of hypoxanthine—a purine base predominantly found in muscle tissue and a metabolite generated whenFormule :C12H16N4O5Couleur et forme :SolidMasse moléculaire :296.28N1-Methylxylo-guanosine
N1-Methylxylo-guanosine, a purine analog, targets lymphoid cancer via DNA synthesis inhibition and apoptosis.Formule :C11H15N5O5Couleur et forme :SolidMasse moléculaire :297.27N1-Benzoyl pseudouridine
N1-Benzoyl pseudouridine, a purine nucleoside analog, inhibits DNA synthesis and induces apoptosis to combat lymphoid cancers.Formule :C16H16N2O7Couleur et forme :SolidMasse moléculaire :348.315'-DMTr-3'dA(Bz)-methylphosphonami dite
5’-DMTr-3’dA(Bz)-methylphosphonamidite, a purine nucleoside analog, exhibits wide-ranging antitumor activity, specifically targeting indolent lymphoidFormule :C45H51N6O6PCouleur et forme :SolidMasse moléculaire :802.92'-Fluoro-2'-deoxy-arabinoadenosine 5'-triphosphate triethylamine
2’-Fluoro-2’-deoxy-arabinoadenosine 5’-triphosphate (triethylamine) is a purine nucleoside analog with significant antitumor properties, particularly effectiveFormule :C34H75FN9O12P3Couleur et forme :SolidMasse moléculaire :913.933'-β-C-Methyl-N6-isopentenyl adenosine
3’-Beta-C-Methyl-N6-isopentenyl adenosine is an adenosine analog.Formule :C16H23N5O4Couleur et forme :SolidMasse moléculaire :349.382'-Chloro-N6-(3-trifluoromethyl)benzyl adenosine
2’-Chloro-N6-(3-trifluoromethyl)benzyl adenosine, a purine nucleoside analog, exhibits broad antitumor activity, particularly against indolent lymphoidFormule :C18H17ClF3N5O4Couleur et forme :SolidMasse moléculaire :459.812'-O-(2-Methoxyethyl)guanosine 5'-triphosphate ammonium
2’-O-(2-Methoxyethyl)guanosine 5’-triphosphate (ammonium), a purine nucleoside analog, exhibits extensive antitumor properties, particularly against indolentFormule :C13H34N9O15P3Couleur et forme :SolidMasse moléculaire :649.38N7-Methyl-2'-O-(2-methoxyethyl) guanosine
N7-Methyl-2’-O-(2-methoxyethyl) guanosine, a purine nucleoside analog, exhibits broad antitumor activity, particularly against indolent lymphoid malignancies.Formule :C14H21N5O6Couleur et forme :SolidMasse moléculaire :355.352'-Deoxy-2'-fluoro-N3-[3-(tert-butoxycarbonyl) amino]propyluridine
2’-Deoxy-2’-fluoro-N3-[3-(tert-butoxycarbonyl)amino]propyluridine, a purine nucleoside analog, exhibits broad antitumor activity, particularly against indolentFormule :C17H26FN3O7Couleur et forme :SolidMasse moléculaire :403.4(R)-N-(2,3-Dihydro-1H-indenyl)-2-amino adenosine
(R)-N-(2,3-Dihydro-1H-indenyl)-2-amino adenosine, a purine analog, targets lymphoid cancer via DNA synthesis inhibition and apoptosis.Formule :C19H22N6O4Couleur et forme :SolidMasse moléculaire :398.42
