Antimétabolite nucléosidique/analogue
Les antimétabolites et analogues des nucléosides sont des composés qui imitent les nucléosides naturels et sont incorporés dans l'ADN lors de la réplication, entraînant la terminaison de la chaîne ou l'inhibition de la synthèse de l'ADN. Ces composés sont largement utilisés comme agents chimiothérapeutiques dans le traitement du cancer et des infections virales. En perturbant la synthèse de l'ADN, les analogues des nucléosides induisent l'arrêt du cycle cellulaire et l'apoptose. Chez CymitQuimica, nous offrons une large gamme d'antimétabolites et d'analogues de nucléosides de haute qualité pour soutenir vos recherches sur le traitement du cancer, la thérapie antivirale et la réplication de l'ADN.
1418 produits trouvés pour "Antimétabolite nucléosidique/analogue"
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1-(β-D-Xylofuranosyl)-N6-(m-methoxybenzyl)adenine
1-(β-D-Xylofuranosyl)-N6-(m-methoxybenzyl)adenine is an adenosine analog.Formule :C18H21N5O5Couleur et forme :SolidMasse moléculaire :387.39N1-Methyl-2'-β-C-methyl inosine
N1-Methyl-2’-beta-C-methyl inosine, a purine nucleoside analog, exhibits broad antitumor activity against indolent lymphoid malignancies through mechanisms thatFormule :C12H16N4O5Couleur et forme :SolidMasse moléculaire :296.283'-β-C-Methyl-N6-isopentenyl adenosine
3’-Beta-C-Methyl-N6-isopentenyl adenosine is an adenosine analog.Formule :C16H23N5O4Couleur et forme :SolidMasse moléculaire :349.385'-O-DMTr-2'-O-MOE inosine 3'-P-methyl phosphonamidite
5’-O-DMTr-2’-O-MOE inosine 3’-P-methyl phosphonamidite, a purine nucleoside analog, exhibits extensive antitumor activity specific to indolent lymphoidFormule :C41H52N5O8PCouleur et forme :SolidMasse moléculaire :773.856-Methoxypurine-9-β-D-(3-methoxy riboside)
6-Methoxypurine riboside is a purine analog with anti-lymphoma activity via DNA synthesis inhibition and apoptosis induction.Formule :C12H16N4O5Couleur et forme :SolidMasse moléculaire :296.288-Chloro-2'-O-methyl inosine
8-Chloro-2’-O-methyl inosine, a purine nucleoside analog, exhibits broad antitumor activity against indolent lymphoid malignancies.Formule :C11H13ClN4O5Couleur et forme :SolidMasse moléculaire :316.72-Diethoxymethyl adenosine
2-Diethoxymethyl adenosine, an adenosine analog, dilates smooth muscle, inhibits cancer, and leads to drugs like Acadesine.Formule :C23H31N5O10Couleur et forme :SolidMasse moléculaire :537.52Detiviciclovir
CAS :Detiviciclovir (AM365) is an antiviral nucleoside analogue [1] .Formule :C9H13N5O2Couleur et forme :SolidMasse moléculaire :223.235'-O-Benzoyl-3'-O-(4-methoxybenzyl)-2'-O,4'-C-methyleneuridine
5’-O-Benzoyl-3’-O-(4-methoxybenzyl)-2’-O,4’-C-methyleneuridine is a purine nucleoside analog with broad antitumor activity, primarily targeting indolentFormule :C25H24N2O8Couleur et forme :SolidMasse moléculaire :480.47N6-Methyl-2'-O-(2-methoxyethyl) adenosine
N6-Methyl-2’-O-(2-methoxyethyl) adenosine, a purine nucleoside analog, exhibits broad antitumor activity, particularly against indolent lymphoid malignancies.Formule :C14H21N5O5Couleur et forme :SolidMasse moléculaire :339.356-Amino-3-(furan-2-yl)-4-methoxy-1-(β-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine
6-Amino-3-(furan-2-yl)-4-methoxy-1-(β-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine, a purine nucleoside analogue, exhibits broad antitumor activity byFormule :C15H17N5O6Couleur et forme :SolidMasse moléculaire :363.33N4-Benzoyl-2'-deoxy-2'-fluoro-β-D-arabinocytidine
N4-Benzoyl-2’-deoxy-2’-fluoro-β-D-arabinocytidine, a purine nucleoside analog, exhibits widespread antitumor activity, particularly against indolent lymphoidFormule :C16H16FN3O5Couleur et forme :SolidMasse moléculaire :349.313'-O-(4,4'-Dimethoxy trityl)-2'-O-(2-methoxyethyl)-5-methyluridine
3’-O-(4,4’-Dimethoxy trityl)-2’-O-(2-methoxyethyl)-5-methyluridine, a purine nucleoside analog, exhibits extensive antitumor properties against indolentFormule :C34H38N2O9Couleur et forme :SolidMasse moléculaire :618.67N7-Methyl-2'-O-(2-methoxyethyl) guanosine
N7-Methyl-2’-O-(2-methoxyethyl) guanosine, a purine nucleoside analog, exhibits broad antitumor activity, particularly against indolent lymphoid malignancies.Formule :C14H21N5O6Couleur et forme :SolidMasse moléculaire :355.356-Amino-4-methoxy-1-(2-deoxy-β-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine
CAS :6-Amino-4-methoxy-1-(2-deoxy-β-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine, a pyrimidine nucleoside analog, exhibits a broad spectrum of biochemical andFormule :C11H15N5O4Couleur et forme :SolidMasse moléculaire :281.27Isocytosine
CAS :Compound PDK0016, with CAS No. 108-53-2, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound PDK0016 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.Formule :C4H5N3OCouleur et forme :White To Off-White SolidMasse moléculaire :111.13'-β-C-Methyl-2-thiouridine
3’-β-C-Methyl-2-thiouridine, a purine nucleoside analog, exhibits extensive antitumor activity, particularly against indolent lymphoid malignancies.Formule :C10H14N2O5SCouleur et forme :SolidMasse moléculaire :274.292'-Deoxy-2'-fluoroguanosine 5'-monophosphate triethyl ammonium
2’-Deoxy-2’-fluoroguanosine 5’-monophosphate triethyl ammonium, a purine nucleoside analog, exhibits broad antitumor activity specifically targeting indolentFormule :C22H43FN7O7PCouleur et forme :SolidMasse moléculaire :567.59Xylocytidine
CAS :Xylocytidine is a biochemical.Formule :C9H13N3O5Couleur et forme :SolidMasse moléculaire :243.22N1-(2-Methyl)propyl pseudouridine
N1-(2-Methyl)propyl pseudouridine, a purine analog, targets lymphoid cancer by inhibiting DNA synthesis and inducing apoptosis.Formule :C13H20N2O6Couleur et forme :SolidMasse moléculaire :300.31N4-Benzoyl-3'-O-DMT-2'-O-(2-methoxyethyl)-5-methylcytidine
N4-Benzoyl-3'-O-DMT cytidine analog inhibits DNA methyltransferases like Zebularine.Formule :C41H43N3O9Couleur et forme :SolidMasse moléculaire :721.79N3,5-Dimethyl-2'-O-(2-methoxyethyl) uridine
N3,5-Dimethyl-2’-O-(2-methoxyethyl) uridine, a purine nucleoside analog, exhibits broad antitumor activity, particularly against indolent lymphoid malignancies.Formule :C14H22N2O7Couleur et forme :SolidMasse moléculaire :330.332'-Deoxy-2'-fluoro-N3-(n-dodecyl)uridine
2’-Deoxy-2’-fluoro-N3-(n-dodecyl)uridine, a purine nucleoside analog, exhibits broad antitumor activity, particularly against indolent lymphoid malignancies.Formule :C21H35FN2O5Couleur et forme :SolidMasse moléculaire :414.51Flurocitabine HCl
CAS :Fluorocitabine HCl, a cytarabine analog, hydrolyzes into ara-FC and ara-FU, showing antitumor effects in leukemia and solid cancers.Formule :C9H11ClFN3O4Degré de pureté :99.76% - 99.83%Couleur et forme :SoildMasse moléculaire :279.655'(R)-C-Methyl-5-fluorouridine
5’(R)-C-Methyl-5-fluorouridine, a uridine analogue, possesses potential antiepileptic properties.Formule :C10H13FN2O6Couleur et forme :SolidMasse moléculaire :276.22Py-MAA-Val-Cit-PAB-DX8951
CAS :Py-MAA-Val-Cit-PAB-DX8951, a purine toxin, serves as an intermediate in the synthesis of antibody-drug conjugates [1].Formule :C57H66FN11O13SCouleur et forme :SolidMasse moléculaire :1164.265'-DMTr-3'dA(Bz)-methylphosphonami dite
5’-DMTr-3’dA(Bz)-methylphosphonamidite, a purine nucleoside analog, exhibits wide-ranging antitumor activity, specifically targeting indolent lymphoidFormule :C45H51N6O6PCouleur et forme :SolidMasse moléculaire :802.9UnyLinker 12 TEA
UnyLinker 12 TEA is a versatile linker used in the synthesis of oligoribonucleotides.Formule :C39H35NO10C6H15NCouleur et forme :SolidMasse moléculaire :778.346555'-O-DMTr-2',2'-difluoro-dC(Bz)-methyl phosphonamidite
5’-O-DMTr-2’,2’-difluoro-dC(Bz)-methyl phosphonamidite is a purine nucleoside analog with extensive antitumor activity against indolent lymphoid malignancies.Formule :C44H49F2N4O7PCouleur et forme :SolidMasse moléculaire :814.852'-β-C-Methyl-3-deazauri dine
CAS :2’-β-C-Methyl-3-deazauridine, a purine nucleoside analogue, exhibits wide antitumor activity specifically against indolent lymphoid malignancies.Formule :C11H15NO6Couleur et forme :SolidMasse moléculaire :257.24N4-(3,3,3-Trifluoropropanoyl)cytidine
N4-(3,3,3-Trifluoropropanoyl)cytidine, a cytidine analog, inhibits DNA methyltransferases, possibly anti-metabolic and anti-cancer.Formule :C12H14F3N3O6Couleur et forme :SolidMasse moléculaire :353.25Rev 2'-O-MOE-5MeC(Bz)-5'-amidite
Rev 2’-O-MOE-5MeC(Bz)-5’-amidite, a purine nucleoside analog, exhibits broad antitumor activity, particularly against indolent lymphoid malignancies.Formule :C50H60N5O10PCouleur et forme :SolidMasse moléculaire :922.016-Amino-4-hydrozino-1-(2-deoxy-β-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine
6-Amino-4-hydrozino-1-(2-deoxy-β-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine, a pyrimidine nucleoside analog, boasts a broad spectrum of biochemical andFormule :C10H17N7O3Couleur et forme :SolidMasse moléculaire :283.29m7GpppUmpG
CAS :m7GpppUmpG, a trinucleotide cap analogue, enables RNA synthesis with cap 0 or 1 structures.Formule :C31H42N12O26P4Couleur et forme :SolidMasse moléculaire :1122.632'-O-Methyladenosine 5'-monophosphate triethyl ammonium
2’-O-Methyladenosine 5’-monophosphate triethyl ammonium is an adenosine analog.Formule :C11H14N5O7P2Couleur et forme :SolidMasse moléculaire :359.231-(β-D-Xylofuranosyl)-N6-(m-trifluoromethylbenzyl)adenine
1-(β-D-Xylofuranosyl)-N6-(m-trifluoromethylbenzyl)adenine is an adenosine analog.Formule :C18H18F3N5O4Couleur et forme :SolidMasse moléculaire :425.36N1-Methyl-2'-O-(2-methoxyethyl) adenosine
N1-Methyl-2’-O-(2-methoxyethyl) adenosine, a purine nucleoside analog, exhibits broad antitumor effects, particularly against indolent lymphoid malignancies.Formule :C14H21N5O5Couleur et forme :SolidMasse moléculaire :339.358-Chloro-2'-deoxy-2'-fluoro-arabino adenosine
8-Chloro-2’-deoxy-2’-fluoro-arabino adenosine, a purine nucleoside analog, demonstrates broad antitumor activity against indolent lymphoid malignancies.Formule :C10H11ClFN5O3Couleur et forme :SolidMasse moléculaire :303.682-(3-Methyln-propylidene hydrazino) adenosine
2-(3-Methyln-propylidene hydrazino) adenosine: a purine analog with antitumor properties, inhibits DNA synthesis, induces apoptosis.Formule :C15H23N7O4Couleur et forme :SolidMasse moléculaire :365.39L-Inosine
CAS :L-Inosine, an endogenous purine nucleoside from adenosine metabolism, has anti-inflammatory, antinociceptive, immunomodulatory, and neuroprotective properties.Formule :C10H12N4O5Couleur et forme :SolidMasse moléculaire :268.233'-Deoxy-N1-Methyl inosine
3’-Deoxy-N1-Methyl inosine, a purine nucleoside analog, exhibits broad antitumor activity against indolent lymphoid malignancies.Formule :C11H14N4O4Couleur et forme :SolidMasse moléculaire :266.252-(P-Cyanophenyl methylidene hydrazino) adenosine
2-(P-Cyanophenyl methylidene hydrazino) adenosine: a purine analog with antitumor effects via DNA synthesis inhibition and apoptosis.Formule :C18H18N8O4Couleur et forme :SolidMasse moléculaire :410.396-O-Methyl-2'-O-methylinosine
6-O-Methyl-2’-O-methylinosine is a purine nucleoside analog known for its broad antitumor activity, particularly against indolent lymphoid malignancies.Formule :C12H16N4O5Couleur et forme :SolidMasse moléculaire :296.28N6-Benzoyl-3'-O-DMT-2'-O-(2-methoxyethyl) adenosine
N6-Benzoyl-3'-O-DMT-adenosine is a purine analog with antitumor effects by hindering DNA synthesis and inducing apoptosis.Formule :C41H41N5O8Couleur et forme :SolidMasse moléculaire :731.79N6-Methyl-2'-β-C-ethynyl adenosine
N6-Methyl-2’-beta-C-ethynyl adenosine is a purine nucleoside analog.Formule :C13H15N5O4Couleur et forme :SolidMasse moléculaire :305.295-(2-Hydroxyethyl)-2',3'-di-O-toluoyl-2'-deoxyuridine
5-(2-Hydroxyethyl)-2',3'-di-O-toluoyl-2'-deoxyuridine, a purine nucleoside analog, exhibits widespread antitumor activity specifically against indolent lymphoidFormule :C27H28N2O8Couleur et forme :SolidMasse moléculaire :508.522-Amino-6-O-methyl-2'-O-methyl purine riboside
2-Amino-6-O-methyl-2’-O-methyl purine riboside, a purine nucleoside analog, exhibits broad antitumor activity, particularly against indolent lymphoidFormule :C12H17N5O5Couleur et forme :SolidMasse moléculaire :311.296-Methoxypurine-9-β-D-5'(R)-C-methylriboside
6-Methoxypurine-9-β-D-5’(R)-C-methylriboside, an analog of hypoxanthine—a purine base predominantly found in muscle tissue and a metabolite generated whenFormule :C12H16N4O5Couleur et forme :SolidMasse moléculaire :296.28N1-Benzoyl pseudouridine
N1-Benzoyl pseudouridine, a purine nucleoside analog, inhibits DNA synthesis and induces apoptosis to combat lymphoid cancers.Formule :C16H16N2O7Couleur et forme :SolidMasse moléculaire :348.311-(β-D-Xylofuranosyl)-N6-Isopentenyladenine
1-(β-D-Xylofuranosyl)-N6-Isopentenyladenine is an adenosine analog.Formule :C15H21N5O4Couleur et forme :SolidMasse moléculaire :335.36
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