Antimétabolite nucléosidique/analogue
Les antimétabolites et analogues des nucléosides sont des composés qui imitent les nucléosides naturels et sont incorporés dans l'ADN lors de la réplication, entraînant la terminaison de la chaîne ou l'inhibition de la synthèse de l'ADN. Ces composés sont largement utilisés comme agents chimiothérapeutiques dans le traitement du cancer et des infections virales. En perturbant la synthèse de l'ADN, les analogues des nucléosides induisent l'arrêt du cycle cellulaire et l'apoptose. Chez CymitQuimica, nous offrons une large gamme d'antimétabolites et d'analogues de nucléosides de haute qualité pour soutenir vos recherches sur le traitement du cancer, la thérapie antivirale et la réplication de l'ADN.
1388 produits trouvés pour "Antimétabolite nucléosidique/analogue"
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Uridine
CAS :<p>Uridine (Uridin) is a nucleoside compound, a base that makes up RNA, that replaces thymine in DNA during transcriptione. Cost-effective and quality-assured.</p>Formule :C9H12N2O6Degré de pureté :99.08% - 99.82%Couleur et forme :White To Off-White Crystalline PowderMasse moléculaire :244.2Ganciclovir sodium
CAS :<p>Ganciclovir sodium, a sodium salt with anti-CMV and HSV-1 antiviral properties.</p>Formule :C9H13N5NaO4Degré de pureté :99.93%Couleur et forme :SolidMasse moléculaire :278.22Raltitrexed
CAS :<p>Raltitrexed (D1694)(IC50 of 9 nM), a thymidylate synthase inhibitor, is used for the inhibition of L1210 cell growth.</p>Formule :C21H22N4O6SDegré de pureté :98.99% - 99.29%Couleur et forme :Yellow Crystalline PowderMasse moléculaire :458.498-Azaguanine
CAS :<p>8-Azaguanine (SK 1150) is a purine analogue with potential antineoplastic activity.</p>Formule :C4H4N6ODegré de pureté :98.66% - >99.99%Couleur et forme :White To Off-White Crystalline PowderMasse moléculaire :152.11DMTr-LNA-5MeU-3-CED-phosphoramidite
CAS :<p>DMTr-LNA-5MeU-3-CED-phosphoramidite is a derivative of nucleoside.</p>Formule :C41H49N4O9PDegré de pureté :98.28%Couleur et forme :SolidMasse moléculaire :772.826-Chloropurine riboside
CAS :<p>6-Chloropurine riboside (6-CPR): purine analog with antitumor, anti-inflammatory, antiviral, antifungal effects, and neuroprotective properties.</p>Formule :C10H11ClN4O4Degré de pureté :96.84%Couleur et forme :SoildMasse moléculaire :286.67002',3'-Bis-(O-t-butyldimethylsilyl)uridine
CAS :<p>2',3'-Bis-(O-t-butyldimethylsilyl)uridine is a nucleoside derivative protect the NH2/OH groups of nucleosides.inhibitory on viral replication，AIDS and herpes.</p>Formule :C21H40N2O6Si2Degré de pureté :99.88%Couleur et forme :SolidMasse moléculaire :472.729-(β-D-Xylofuranosyl)adenine
CAS :<p>9-(β-D-Xylofuranosyl)adenine (Adenine xyloside) is an adenine nucleoside analog that is a potential smooth muscle vasodilator.9-(β-D-Xylofuranosyl)adenine has</p>Formule :C10H13N5O4Degré de pureté :99.97%Couleur et forme :SolidMasse moléculaire :267.242'-Deoxy-N4-methylcytidine
CAS :<p>2’-Deoxy-N4-methylcytidine (N(3)-Methyl-2'-deoxycytidine) is a purine nucleoside analog with potential antitumor activity for the study of apoptosis.</p>Formule :C10H15N3O4Degré de pureté :99.61%Couleur et forme :SolidMasse moléculaire :241.24P-2'-deoxyribose
CAS :<p>P-2'-deoxyribose (P-Nucleoside) is a deoxyribose that is widely found in organisms.</p>Formule :C11H15N3O5Degré de pureté :99.71%Couleur et forme :SolidMasse moléculaire :269.25Rabacfosadine
CAS :<p>Rabacfosadine (GS-9219) is a novel prodrug of PMEG, an acyclic nucleotide phosphonate, with antitumor activity for the study of lymphoma.</p>Formule :C21H35N8O6PDegré de pureté :99.06% - 99.37%Couleur et forme :SolidMasse moléculaire :526.533'-Deoxy-3'-fluoroadenosine
CAS :<p>3'-Deoxy-3'-fluoroadenosine is a purine nucleoside analogue with a wide range of anti-tumor and anti-viral activity, and has inhibitory effects on tick-borne</p>Formule :C10H12FN5O3Degré de pureté :99.84%Couleur et forme :SolidMasse moléculaire :269.232'-Deoxy-N2-methylguanosine
CAS :<p>2'-Deoxy-N2-methylguanosine is a purine nucleoside analog that can be used as a chemical probe to study DNA-protein interactions.</p>Formule :C11H15N5O4Degré de pureté :99.79%Couleur et forme :SolidMasse moléculaire :281.27O6-Methyldeoxy guanosine
CAS :<p>O6-Methyldeoxy guanosine, a deoxypurine nucleoside, is a weak inhibitor of the removal of O6-methylguanine from methylated DNA by rat liver enzymes in vitro.</p>Formule :C11H15N5O4Degré de pureté :99.57%Couleur et forme :SolidMasse moléculaire :281.272'-O-Methyl-2-thiouridine
CAS :<p>2'-O-Methyl-2-thiouridine, a purine nucleoside analog present in synthetic thermophilic bacterial tRNAs, is more selective for A than unmodified U.</p>Formule :C10H14N2O5SDegré de pureté :99.89%Couleur et forme :SolidMasse moléculaire :274.295-Bromo-2',3',5'-tri-O-acetyluridine
CAS :<p>5-Bromo-2',3',5'-tri-O-acetyluridine is a purine nucleoside analog that can be used to explore explore improve Parkinson's disease.</p>Formule :C15H17BrN2O9Degré de pureté :99%Couleur et forme :SolidMasse moléculaire :449.21N6-Methyl-2'-O-methyladenosine
CAS :<p>N6-Methyl-2'-O-methyladenosine (N6,2′-O-Dimethyladenosine), a substrate for adiposity and obesity-related genes (FTO), is a reversible modifier compound found</p>Formule :C12H17N5O4Degré de pureté :99.97%Couleur et forme :SolidMasse moléculaire :295.29N6-(p-Methoxybenzyl)adenosine
CAS :<p>Nucleoside Derivatives - 6-Modified purine nucleosides; Drugs and Inhibitors; plant growth regulator, plant hormone</p>Formule :C18H21N5O5Degré de pureté :99.79%Couleur et forme :SolidMasse moléculaire :387.395-Hydroxyuridine
CAS :<p>5-Hydroxyuridine (OHUrd) is a purine nucleoside analogue with potential antitumour activity, showing cytotoxicity against human colon adenocarcinoma cell lines.</p>Formule :C9H12N2O7Degré de pureté :98.76%Couleur et forme :SolidMasse moléculaire :260.25'-O-DMT-N4-Bz-5-Me-dC
CAS :<p>5'-O-DMT-N4-Bz-5-Me-dC (DMT-NBZ-5-METHYL DC) is a modified nucleoside used in the synthesis of nucleoside phosphoramidites.</p>Formule :C38H37N3O7Degré de pureté :98.88%Couleur et forme :SolidMasse moléculaire :647.725-Methyl-5,6-dihydrouridine
CAS :<p>5-Methyl-5,6-dihydrouridine is a minor constituent in the chromosomal RNA of the rat ascites tumor. It can be used for nucleic acid modification.</p>Formule :C10H16N2O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :260.24Adenosine 2'-PEG-Biotin
CAS :<p>Adenosine 2'-PEG-Biotin, a bioreagent derived from adenosine, modulates cellular signaling pathways by mimicking the action of endogenous adenosine and binding to its receptors. This compound is used in research related to bioprobes, biosensors, and diagnostic agents.</p>Formule :C26H40N8O8SCouleur et forme :SolidMasse moléculaire :624.71L-Threonolactone
CAS :<p>L-Threonolactone is a Carbohydrate Derivative.</p>Formule :C4H6O4Couleur et forme :SolidMasse moléculaire :118.09Bis-Pro-5FU
CAS :<p>Bis-Pro-5FU enhances oral uptake and safety of 5-FU, an anti-cancer drug for colorectal and pancreatic tumors.</p>Formule :C10H7FN2O2Couleur et forme :SolidMasse moléculaire :206.17LY 207702
CAS :<p>LY 207702, a difluorinated purine nucleoside, exhibits antitumor activity in preclinical models.</p>Formule :C10H12F2N6O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :302.242'-Fluorothymidine
CAS :<p>2'-Fluorothymidine is a selective substrate for TK2, related to thymidine and methyluridine.</p>Formule :C10H13FN2O5Degré de pureté :99.67%Couleur et forme :SolidMasse moléculaire :260.22Fosteabine
CAS :<p>Fosteabine is an oral and prodrug analog of cytarabine. It is resistant to deoxycytidine deaminase.</p>Formule :C27H50N3O8PDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :575.671-Methylcytosine
CAS :<p>1-Methylcytosine (4-amino-1-methylpyrimidin-2(1H)-one) is a methylated form of the cytosine and can be used as the nucleobase of hachimoji DNA paired with</p>Formule :C5H7N3ODegré de pureté :99.88%Couleur et forme :SolidMasse moléculaire :125.13Rabacfosadine succinate
CAS :<p>Rabacfosadine succinate is the acyclic nucleoside phosphonate PMEG double prodrug.</p>Formule :C25H41N8O10PDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :644.623Thiamiprine
CAS :<p>Thiamiprine is an agent with the activity of antineoplastic.</p>Formule :C9H8N8O2SCouleur et forme :SolidMasse moléculaire :292.28N2-Ethylguanosine
CAS :<p>N2-Ethylguanosine is a Nucleoside Derivative - 2-Modified purine nucleoside.</p>Formule :C12H17N5O5Couleur et forme :SolidMasse moléculaire :311.29Guanoctine hydrochloride
CAS :<p>Guanoctine hydrochloride has antihypertensive activity.</p>Formule :C9H22ClN3Couleur et forme :SolidMasse moléculaire :207.74L-Cytidine
CAS :<p>L-Cytidine, pyrimidine nucleoside in RNA, regulates glial glutamate, brain lipids, catecholamines, and mitochondria.</p>Formule :C9H13N3O5Couleur et forme :SolidMasse moléculaire :243.22L-Guanosine
CAS :<p>L-Guanosine is the L-configuration of Guanosine. Guanosine is a purine nucleoside that has anti-herpesvirus activity [1] [2].</p>Formule :C10H13N5O5Couleur et forme :SolidMasse moléculaire :283.24Enocitabine
CAS :<p>Enocitabine is a nucleoside analog.</p>Formule :C31H55N3O6Degré de pureté :97.22%Couleur et forme :SolidMasse moléculaire :565.78Flurocitabine
CAS :<p>Flurocitabine is a therapeutic agent with antineoplastic activity.</p>Formule :C9H10FN3O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :243.195-Aminouridine
CAS :<p>5-Aminouridine (4-Chloro-2-isopropyl-5-methylphenol(chlorothymol)) modifies nucleobases and is incorporated into the target DNA.</p>Formule :C9H13N3O6Degré de pureté :99.53%Couleur et forme :SolidMasse moléculaire :259.225-OHdU
CAS :<p>5-OHdU (5-OHdU) is a major oxidation product of 2'-Deoxycytidine and can be incorporated into DNA in vitro.</p>Formule :C9H12N2O6Degré de pureté :99.5%Couleur et forme :SolidMasse moléculaire :244.22'-Deoxy-L-guanosine
CAS :<p>2'-Deoxy-L-guanosine is a nucleoside that shows antibiotic properties by inhibiting protein synthesis, leading to cell death.</p>Formule :C10H13N5O4Couleur et forme :SolidMasse moléculaire :267.245-Ethynyluridine
CAS :<p>5-Ethynyluridine marks new RNA for RICK, capturing proteins on various RNAs, even nonpolyadenylated types.</p>Formule :C11H12N2O6Degré de pureté :99.78%Couleur et forme :SolidMasse moléculaire :268.221-Acetyl-3-o-toluyl-5-fluorouracil
CAS :<p>1-Acetyl-3-o-toluyl-5-fluorouracil is a potent antineoplastic agent.</p>Formule :C14H11FN2O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :290.25Peldesine
CAS :<p>Peldesine (BCX 34), an oral purine nucleoside phosphorylase blocker, halts T-cell growth; used in CTCL, psoriasis, HIV research. IC50: 800 nM.</p>Formule :C12H11N5ODegré de pureté :99.27% - 99.9%Couleur et forme :SolidMasse moléculaire :241.25GS-6620 PM
CAS :<p>GS-6620 PM, oral Hep C polymerase inhibitor prodrug, is a potent GS-6620 derivative with limited activity against other viruses.</p>Formule :C13H15N5O4Degré de pureté :98.52% - 98.7%Couleur et forme :SolidMasse moléculaire :305.295'-ODMT cEt m5U Phosphoramidite (Amidite)
CAS :<p>5'-ODMT cEt m5U Phosphoramidite Amidite, a locked nucleic acid (LNA) analog, demonstrates exceptional safety and antisense activity [1] [2].</p>Formule :C42H51N4O9PCouleur et forme :SolidMasse moléculaire :786.85Sapacitabine
CAS :<p>Sapacitabine (CS682) is a nucleoside analog precursor with anticancer activity used in the study of leukemia.</p>Formule :C26H42N4O5Degré de pureté :98.82%Couleur et forme :SolidMasse moléculaire :490.64Homouridine
CAS :<p>Homouridine, an analogue of uridine, functions as an intermediate in the synthesis of MMP-2 inhibitor (compound I, IC50 = 150 μM).</p>Formule :C10H14N2O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :258.235'-ODMT cEt N-Bz A Phosphoramidite (Amidite)
CAS :<p>5'-ODMT cEt N-Bz A Phosphoramidite Amidite, a locked nucleic acid (LNA) analogue, exhibits hybridization and mismatch discrimination capabilities similar to LNA, and shows resistance to exonuclease digestion [1].</p>Formule :C49H54N7O8PCouleur et forme :SolidMasse moléculaire :899.975'-ODMT cEt N-Bzm5 C Phosphoramidite (Amidite)
CAS :<p>5'-ODMT cEt N-Bzm5 C Phosphoramidite is a strong modified nucleic acid analog for antisense oligos.</p>Formule :C49H56N5O9PCouleur et forme :SolidMasse moléculaire :889.97Raluridine
CAS :<p>Raluridine is an HIV treatment inhibiting RNA-directed DNA polymerase with IC50 of 1.8 microM, compared to FLT, AZT, ddI, and ddC.</p>Formule :C9H10ClFN2O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :264.642'-Deoxypseudoisocytidine
CAS :<p>2'-Deoxypseudoisocytidine is a nucleoside analogue.</p>Formule :C9H13N3O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :227.22
