RAAS
Les inhibiteurs du système rénine-angiotensine-aldostérone (SRAA) sont des composés qui ciblent la voie du SRAA, principalement connue pour son rôle dans la régulation de la pression artérielle et de l'équilibre hydrique, mais qui influence également l'angiogenèse. La voie du SRAA peut contribuer au développement de nouveaux vaisseaux sanguins dans les tumeurs, soutenant ainsi leur croissance. Inhiber les composants du SRAA peut donc avoir des effets anti-angiogéniques, rendant ces inhibiteurs précieux dans le traitement de certains cancers et troubles vasculaires. Chez CymitQuimica, nous offrons une gamme d'inhibiteurs de haute qualité du SRAA pour soutenir vos recherches en biologie cardiovasculaire, oncologie et angiogenèse.
87 produits trouvés pour "RAAS"
Trier par
Degré de pureté (%)
0
100
|
0
|
50
|
90
|
95
|
100
Losartan potassium
CAS :<p>Losartan potassium (DuP-753 potassium) , an Angiotensin II Receptor Blocker, selectively and competitively blocks the binding of angiotensin II to the</p>Formule :C22H22ClKN6ODegré de pureté :99.9% - >99.99%Couleur et forme :White To Off-White Crystalline PowderMasse moléculaire :461.01Telmisartan
CAS :<p>Telmisartan (BIBR 277) is an Angiotensin 2 Receptor Blocker. The mechanism of action of telmisartan is as an Angiotensin 2 Receptor Antagonist.</p>Formule :C33H30N4O2Degré de pureté :99.88% - 99.97%Couleur et forme :White Or Off White Crystalline PowderMasse moléculaire :514.62Zansecimab
CAS :<p>Zansecimab (LY-3127804) is a monoclonal antibody targeting angiopoietin 2 (Ang 2) for the study of cardiovascular and immune diseases.</p>Degré de pureté :97.8% (SDS-PAGE); 99.7% (SEC-HPLC) - 97.8% (SDS-PAGE); 99.7% (SEC-HPLC)Couleur et forme :LiquidPomisartan 2HCl
<p>Pomisartan 2HCl (BIBR363 2HCL) is a small molecule AT1R antagonist used to study heart failure and hypertension.</p>Formule :C31H32Cl2N4O2Degré de pureté :99.88%Couleur et forme :SoildMasse moléculaire :563.52Olmesartan Medoxomil
CAS :<p>Olmesartan Medoxomil (Benicar) is an angiotensin II type 1 receptor blocker that is used to manage hypertension.</p>Formule :C29H30N6O6Degré de pureté :99.89% - 99.9%Couleur et forme :White To Off-White Crystalline PowderMasse moléculaire :558.59Losartan
CAS :<p>Losartan (DuP-753) is an angiotensin II receptor antagonist.</p>Formule :C22H23ClN6ODegré de pureté :99.48% - >99.99%Couleur et forme :Off White Solid PowderMasse moléculaire :422.91Renin FRET Substrate I
CAS :Renin FRET Substrate I, designed for human renin, contains angiotensinogen's N-terminal cleavage site.Formule :C90H120N22O16SMasse moléculaire :1798.15Angiotensin II (3-8), human TFA
<p>Angiotensin II (3-8), human (TFA) is an angiotensin AT1 receptor agonist with less activity.</p>Formule :C42H55F3N8O10Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :888.93Tetrahydro Aldosterone
CAS :<p>Tetrahydro Aldosterone is a steroidal compound that inhibits the adrenal angiotensin II receptor, with an IC50 of 10 μM.</p>Formule :C21H32O5Couleur et forme :SolidMasse moléculaire :364.48TRV055 acetate
<p>TRV055 acetate is a ligand of angiotensin II type 1 receptor and stimulates cellular Gq-mediated signaling.</p>Formule :C44H61N9O11Degré de pureté :99.84%Couleur et forme :SolidMasse moléculaire :892.01PRO20
<p>PRO20 is a specific and competitive antagonist of the (pro)renin receptor (PRR). It inhibits the calcium influx induced by Proproin with an IC50 value of 81 nmol/L. By blocking the binding of Prorenin to PRR, PRO20 inhibits the activation of the renin-angiotensin system (RAS), reducing the production of angiotensin II (Ang II) and exerting antihypertensive effects. PRO20 holds promise for research in antihypertensive agents.</p>Couleur et forme :Odour SolidAlunacedase alfa
CAS :<p>Alunacedase alfa (APN-01) is an angiotensin-converting enzyme 2 with antiviral activity.</p>Degré de pureté :99.1% (SDS-PAGE); 99.9% (SEC-HPLC) - 99.1% (SDS-PAGE); 99.9% (SEC-HPLC)Couleur et forme :LiquidEprosartan
CAS :<p>Eprosartan is a selective AT1 receptor blocker with IC50s of 9.2 nM (rat) and 3.9 nM (human), used for hypertension.</p>Formule :C23H24N2O4SDegré de pureté :>99.99%Couleur et forme :SolidMasse moléculaire :424.51Aclerastide
CAS :<p>Aclerastide, an angiotensin receptor agonist, decreases fibrosis in wounds; effect increases with use duration, blocked by AT antagonist.</p>Formule :C42H64N12O11Couleur et forme :SolidMasse moléculaire :913.03[Sar1, Ile8]-Angiotensin II
CAS :<p>[Sar1, Ile8]-Angiotensin II(3TFA) is a peptide that has multiple effects on vascular smooth muscle.</p>Formule :C46H73N13O10Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :968.15TRV056
CAS :<p>TRV056 is a Gq-biased AT1R agonist effective in Gq-mediated signaling and a basis for similar drug development.</p>Formule :C52H74N14O13Couleur et forme :SolidMasse moléculaire :1103.249C-Type Natriuretic Peptide (1-53), human
CAS :<p>CNP, from natriuretic family, first in pigs, now in other species, processes into CNP-22/CNP-53, similar to ANP/BNP, with varying potencies.</p>Formule :C251H417N81O71S3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :5801.77[Sar1, Ile8]-Angiotensin II acetate
<p>'[Sar1, Ile8]-Angiotensin II acetate triggers oxidases and prompts superoxide in muscles; has varied vascular impacts.</p>Formule :C48H77N13O12Degré de pureté :99.36%Couleur et forme :SolidMasse moléculaire :1028.2Handle region peptide, rat
CAS :<p>Rat handle region peptide acts as prorenin receptor blocker, curbs diabetic kidney disease, and reduces eye inflammation.</p>Formule :C54H101N15O12SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :1184.54Azilsartan Medoxomil Potassium
CAS :<p>Azilsartan Medoxomil Potassium (TAK-491 Potassium) is an orally administered angiotensin II receptor type 1 antagonist with IC50 of 0.62 nM, which used in the treatment of adults with essential hypertension.</p>Formule :C30H23N4O8·KDegré de pureté :98.72%Couleur et forme :SolidMasse moléculaire :606.62[Sar1, Ile8]-Angiotensin II TFA
<p>[Sar1,Ile8]-Angiotensin II (TFA) contracts arteries and affects cell growth in vascular muscle.</p>Formule :C48H74F3N13O12Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1082.18CGP-42112 acetate
<p>CGP-42112 acetate is a potent angiotensin receptor AT2 agonist that inhibits the increase in protein kinase A activity produced by LPS.</p>Formule :C54H73N13O13Degré de pureté :99.06% - 99.92%Couleur et forme :SoildMasse moléculaire :1112.24Saralasin
CAS :Competitive non-selective angiotensin II antagonist.Formule :C42H65N13O10Degré de pureté :98%Couleur et forme :PowderMasse moléculaire :912Angiotensin II (1-4), human
CAS :<p>Angiotensin II constricts blood vessels and boosts blood pressure by escalating norepinephrine release.</p>Formule :C24H37N7O8Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :551.59Angiotensin II (1-4), human TFA
<p>Angiotensin II is a potent direct vasoconstrictor, causing arteries and veins to constrict, so leading to an increase in blood pressure.</p>Formule :C26H38F3N7O10Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :665.62Angiotensin II (5-8), human
CAS :<p>Angiotensin II (5-8) is an endogenous C-terminal fragment of the peptide vasoconstrictor angiotensin II</p>Formule :C26H36N6O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :512.6Valsartan Methyl Ester
CAS :<p>Valsartan Methyl Ester is a potent angiotensin II receptor antagonist, IC50= 0.06uM.</p>Formule :C25H31N5O3Degré de pureté :99.54%Couleur et forme :SolidMasse moléculaire :449.55Aliskiren D6 Hydrochloride
CAS :<p>Aliskiren (CGP 60536) D6 Hydrochloride is a deuterium-labeled Aliskiren. Aliskiren hemifumarate is a direct and orally active renin inhibitor (IC50: 1.5 nM).</p>Formule :C30H54ClN3O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :594.26Brain Natriuretic Peptide (1-32), rat
CAS :<p>Rat Brain Natriuretic Peptide (1-32) is a 32-amino-acid peptide from heart, released when ventricles stretch excessively.</p>Formule :C146H239N47O44S3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :3452.94Angiotensin II 5-valine
CAS :<p>ngiotensin II 5-valine is an angiotensin II analog which is an agonist at angiotensin receptors.</p>Formule :C49H69N13O12Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :N/AAngiotensin amide
CAS :<p>Angiotensin amide, an octapeptide amide, can be used to increase blood pressure by vasoconstriction.</p>Formule :C49H70N14O11Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1031.17Nesvacumab
CAS :<p>Nesvacumab (REGN910) is a fully human monoclonal antibody targeting Angiopoietin 2 (Ang2), which can be used for studying advanced solid tumors.</p>Degré de pureté :98.7% (SDS-PAGE); 95.7% (SEC-HPLC) - 99.11% (SEC-HPLC)Couleur et forme :LiquidA 779
CAS :<p>A 779 is a potent antagonist of the G-protein-coupled receptor Mas, the Ang1-7 receptor, which is distinct from conventional AngII.</p>Formule :C39H60N12O11Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :872.97BIBS 39
CAS :<p>BIBS 39 is a new nonpeptide angiotensin II (AII) receptor antagonist.</p>Formule :C32H36N4O3Degré de pureté :99.28%Couleur et forme :SolidMasse moléculaire :524.65Valsartan-d9
CAS :<p>Valsartan D9: deuterium-labeled, angiotensin II receptor antagonist, treats hypertension & heart failure.</p>Formule :C24H29N5O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :444.57Losartan (D4 Carboxylic Acid)
CAS :<p>Losartan D4 Carboxylic Acid is the deuterium labeled Losartan, which is an angiotensin II receptor antagonist.</p>Formule :C22H21ClN6O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :440.92Azilsartan-d5
CAS :<p>Azilsartan (TAK-536) D5 is the deuterium-labeled Azilsartan. Azilsartan is a specific antagonist of the angiotensin II type 1 receptor.</p>Formule :C25H20N4O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :461.48PD 123319 ditrifluoroacetate
CAS :<p>PD 123319 ditrifluoroacetate is a selective non-peptide AT2 receptor antagonist with IC50 of 34 nM.</p>Formule :C35H34F6N4O7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :736.66Olmesartan-d4
CAS :<p>Olmesartan D4 is the deuterium labeled Olmesartan. Olmesartan is an antagonist of angiotensin II receptor (AT1R) used to treat high blood pressure.</p>Formule :C24H26N6O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :450.53Candesartan-d4
CAS :<p>Candesartan D4 is the deuterium labeled Candesartan. Candesartan is an antagonist of angiotensin II receptor.</p>Formule :C24H20N6O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :444.48Angiotensin II (3-8), human
CAS :<p>Angiotensin II (3-8), human is a less effective agonist at the angiotensin AT1 receptor.</p>Couleur et forme :SolidOlodanrigan
CAS :<p>Olodanrigan (EMA401), a highly selective AT2R antagonist, inhibition of augmented AngII/AT2R induced p38 and p42/p44 MAPK activation.</p>Formule :C32H29NO5Degré de pureté :98.33%Couleur et forme :SolidMasse moléculaire :507.58Angiotensin I/II (1-6)
CAS :<p>Angiotensin I/II (1-6) is a peptide (ASP-ARG-VAL-TYR-ILE-HIS) that contains the amino acids 1-6 and is converted from Angiotensin I/II peptide.</p>Formule :C36H55N11O10Degré de pureté :99.44%Couleur et forme :SolidMasse moléculaire :801.89Olmesartan
CAS :<p>Olmesartan (RNH 6270) is an Angiotensin II Type I receptor antagonist.</p>Formule :C24H26N6O3Degré de pureté :91.89% - 99.81%Couleur et forme :White To Beige Solid SolidMasse moléculaire :446.5BTB06584
CAS :<p>BTB06584: IF1-dependent F1 Fo-ATPase inhibitor; novel AHAS inhibitor targeting MTB.</p>Formule :C19H12ClNO6SDegré de pureté :97.63% - ≥95%Couleur et forme :SolidMasse moléculaire :417.82Angiotensin II 5-valine TFA
<p>Angiotensin II 5-valine TFA is an agonist of angiotensin receptor.</p>Formule :C51H70F3N13O14Degré de pureté :99.69%Couleur et forme :SolidMasse moléculaire :1146.18PD 123319
CAS :<p>PD 123319 ((S)-(+)-PD 123319) is a potent, selective AT2 angiotensin II receptor antagonist.</p>Formule :C31H32N4O3Degré de pureté :98.61% - 99.65%Couleur et forme :SolidMasse moléculaire :508.61Trans-Tranilast
CAS :<p>Trans-Tranilast is an antiallergic drug developed by Kissei Pharmaceuticals. It has been used for the treatment of allergic disorders such as atopic dermatitis.</p>Formule :C18H17NO5Degré de pureté :99.41% - ≥95%Couleur et forme :SolidMasse moléculaire :327.33Eprosartan Mesylate
CAS :<p>Eprosartan Mesylate (SKF-108566J) is a competitive and reversible Angiotensin II Receptor Blocker.</p>Formule :C23H24N2O4S·CH4O3SDegré de pureté :99.72% - 99.93%Couleur et forme :A White To Off- White PowderMasse moléculaire :520.62VTP-27999 TFA
CAS :<p>VTP-27999 TFA is an inhibitor of Renin (IC50 : 0.47 nM).</p>Formule :C28H42ClF3N4O7Degré de pureté :98.84%Couleur et forme :SolidMasse moléculaire :639.1
![[Sar1, Ile8]-Angiotensin II](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTM%2Fthumb-webp%2FT7575.webp&w=3840&q=75)
![[Sar1, Ile8]-Angiotensin II acetate](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTM%2Fthumb-webp%2FT7575L1.webp&w=3840&q=75)
