Récepteur des androgènes
Le récepteur aux androgènes (AR) est un récepteur hormonal nucléaire activé par la liaison aux androgènes, tels que la testostérone et la dihydrotestostérone. Ce récepteur joue un rôle crucial dans le développement et le maintien des caractéristiques masculines, ainsi que dans la régulation de plusieurs processus physiologiques, notamment la croissance musculaire, la libido et la densité osseuse. Les inhibiteurs du récepteur aux androgènes sont largement étudiés dans le contexte du cancer de la prostate, où la signalisation de l'AR est souvent régulée à la hausse. Chez CymitQuimica, nous offrons une gamme de modulateurs du récepteur aux androgènes de haute qualité pour soutenir vos recherches en endocrinologie, biologie du cancer et régulation hormonale.
229 produits trouvés pour "Récepteur des androgènes"
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Darolutamide
CAS :Darolutamide (BAY-1841788) is an androgen receptor (AR) antagonist that blocks AR nuclear translocation (Ki: 11 nM).Formule :C19H19ClN6O2Degré de pureté :97.36% - >99.99%Couleur et forme :SolidMasse moléculaire :398.85Ref: TM-T6915
1mg50,00€2mg66,00€5mg100,00€1mL*10mM (DMSO)101,00€10mg158,00€25mg250,00€50mg358,00€100mg512,00€200mg732,00€Dimethylcurcumin
CAS :Dimethylcurcumin (ASC-J9) (ASC-J9) is an androgen receptor degradation enhancer.Formule :C23H24O6Degré de pureté :97.36% - 98.96%Couleur et forme :SolidMasse moléculaire :396.43Testosterone acetate
CAS :Testosterone acetate (NSC-523836) is a hormone with in vitro antitumor activity.Formule :C21H30O3Degré de pureté :99.6%Couleur et forme :White To Off-White Crystalline PowderMasse moléculaire :330.46GSK-2881078
CAS :GSK-2881078 is a selective androgen receptor modulato (SARM) that is being evaluated for effects on muscle growth and strength in subjects with muscle wasting.Formule :C14H13F3N2O2SDegré de pureté :98.16% - 98.81%Couleur et forme :SolidMasse moléculaire :330.33MI-136
CAS :MI-136 inhibits expression of androgen receptor (AR) target genes that DHT induced.Formule :C23H21F3N6SDegré de pureté :98.63% - 99.12%Couleur et forme :SolidMasse moléculaire :470.51Ref: TM-T6889
1mg44,00€1mL*10mM (DMSO)92,00€5mg93,00€10mg140,00€25mg264,00€50mg447,00€100mg692,00€200mg964,00€Nandrolone phenylpropionate
CAS :Nandrolone phenylpropionate (Nandrolone phenpropionate) is an androgen receptor agonist. It mainly used to treat women with breast cancer and osteoporosisFormule :C27H34O3Degré de pureté :99.2% - 99.46%Couleur et forme :White Or Milky Crystalline PowderMasse moléculaire :406.56YK11
CAS :YK11 is an androgen receptor partial agonist that activates androgen receptor transcriptional activity in HEK293 cells overexpressing androgen receptors when used at a concentration of 0.1 μM, with osteogenic activity.Formule :C25H34O6Degré de pureté :98.91%Couleur et forme :SoildMasse moléculaire :430.53Androgen receptor-IN-4
CAS :3-[7 ,7- dimethyl-5-oxo -6H-pyrrolo[3,4-b]pyridin-2-yI]-1H-indole-7 -carbonitrile is an androgen receptor modulator.Formule :C18H14N4ODegré de pureté :98.41%Couleur et forme :SolidMasse moléculaire :302.332-hydroxy Flutamide
CAS :2-hydroxy Flutamide is competitive inhibition of androgen receptor (AR) for the treatment of prostate cancerFormule :C11H11F3N2O4Degré de pureté :99.45% - 99.82%Couleur et forme :SolidMasse moléculaire :292.21Testosterone undecanoate
CAS :Testosterone undecanoate is a metabolite of Testosterone, which is a promising androgen for male hormonal contraception.Formule :C30H48O3Degré de pureté :99.45% - 99.788%Couleur et forme :White Crystalline PowderMasse moléculaire :456.7Apalutamide
CAS :Apalutamide (ARN-509) is a small molecule and androgen receptor (AR) antagonist with potential antineoplastic activity.Formule :C21H15F4N5O2SDegré de pureté :99.03% - 99.91%Couleur et forme :SolidMasse moléculaire :477.43AH-3960
CAS :AH-3960 是一种甲状腺激素受体 1 (PTHR1) 激动剂。Formule :C13H22N4O3Degré de pureté :98.44%Couleur et forme :SolidMasse moléculaire :282.34VPC-13163
CAS :VPC-13566 inhibits growth in LNCaP, Enzalutamide-resistant MR49F, lowers AR gene, PSA, TMPRSS2 expression, but not in AR-independent PC3 cells.Formule :C16H14N2Degré de pureté :98.02%Couleur et forme :SolidMasse moléculaire :234.3Ref: TM-T29110
1mg85,00€2mg111,00€1mL*10mM (DMSO)165,00€5mg177,00€10mg269,00€25mg429,00€50mg610,00€100mg820,00€200mg1.071,00€S-23
CAS :S-23 ((S)-3-(4-chloro-3-fluorophenoxy)-N-(4-cyano-3-(trifluoromethyl)phenyl)-2-hydroxy-2-methylpropanamide) is an oral selective androgen receptor modulator (Formule :C18H13ClF4N2O3Degré de pureté :99.55%Couleur et forme :SolidMasse moléculaire :416.75Iprodione
CAS :Iprodione is a fungicide. Iprodione is also used in cannabis testing kits as a component of pesticide mixes.Formule :C13H13Cl2N3O3Degré de pureté :98.82%Couleur et forme :Colorless Crystals Cream To Colorless Odorless PowderMasse moléculaire :330.17Bavdegalutamide
CAS :Bavdegalutamide (ARV-110) is a PROTAC degrader of androgen receptor (AR).Formule :C41H43ClFN9O6Degré de pureté :97.17% - 99.04%Couleur et forme :SolidMasse moléculaire :812.29N-desmethyl Enzalutamide
CAS :N-desmethyl Enzalutamide (N-desmethyl MDV 3100) is the active Enzalutamide metabolite.It is the active metabolite of Enzalutamide.Formule :C20H14F4N4O2SDegré de pureté :99.74%Couleur et forme :SolidMasse moléculaire :450.41Ref: TM-T19450
2mg33,00€5mg50,00€1mL*10mM (DMSO)55,00€10mg71,00€25mg131,00€50mg243,00€100mg355,00€200mg504,00€Enzalutamide carboxylic acid
CAS :Enzalutamide carboxylic acid is an antagonist of androgen receptor (AR) .Formule :C20H13F4N3O3SDegré de pureté :97.88%Couleur et forme :SolidMasse moléculaire :451.39Ref: TM-T8217
1mg63,00€2mg88,00€5mg119,00€1mL*10mM (DMSO)133,00€10mg177,00€25mg299,00€50mg416,00€100mg615,00€Lupeol
CAS :Lupeol (Monogynol B) is a novel androgen receptor inhibitor with anti-inflammatory and antioxidant activity.Formule :C30H50ODegré de pureté :98% - 99.96%Couleur et forme :Needles From Alcohol Acetone White PowderMasse moléculaire :426.72VPC-13566
CAS :VPC-13566 is a BF3-specific small molecule, which effectively inhibited the androgen receptor transcriptional activity and displaced the BAG1L peptide from the
Formule :C18H14N2Degré de pureté :99.55%Couleur et forme :SolidMasse moléculaire :258.32Galeterone
CAS :Galeterone (VN 124) is an oral androgen receptor modulator/CYP17 inhibitor with antiandrogen properties, targeting prostate cancer growth.Formule :C26H32N2ODegré de pureté :99.47% - 99.773%Couleur et forme :SolidMasse moléculaire :388.55CLP-3094
CAS :CLP-3094 (2-([2-(4-CHLOROPHENOXY)ETHYL]THIO)-1H-BE) is a potent androgen receptor BF3 (binding function 3) inhibitor.Formule :C15H13ClN2OSDegré de pureté :99.84%Couleur et forme :SolidMasse moléculaire :304.79JNJ-63576253 free base
CAS :JNJ-63576253 free base (TRC253) is a potent and orally active full antagonist of androgen receptor (AR). JNJ-63576253 can be used for the research of CRPC.Formule :C23H21F3N6O2SDegré de pureté :98.32%Couleur et forme :SolidMasse moléculaire :502.51Ref: TM-T8933
2mg38,00€5mg50,00€10mg85,00€1mL*10mM (DMSO)86,00€25mg159,00€50mg244,00€100mg359,00€200mg512,00€CTK8A3536
CAS :CTK8A3536 ((2-MORPHOLIN-4-YL-4-PHENYL-1,3-THIAZOL-5-YL)METHANOL) is an inhibitor of Androgen receptor.Formule :C14H16N2O2SDegré de pureté :99.62%Couleur et forme :SolidMasse moléculaire :276.35Ref: TM-T8592
1mg84,00€1mL*10mM (DMSO)160,00€5mg167,00€10mg245,00€25mg404,00€50mg567,00€100mg767,00€200mg1.018,00€Ailanthone
CAS :Ailanthone (Δ13-Dehydrochaparrinone) is an effective inhibitor of both full-length androgen receptor (AR) (IC50: 69 nM) and constitutively active truncated ARFormule :C20H24O7Degré de pureté :99.71% - 99.96%Couleur et forme :SolidMasse moléculaire :376.4ARD-2128
CAS :ARD-2128: potent oral PROTAC that degrades AR, curbing prostate cancer growth with no toxicity.Formule :C45H50ClN7O6Degré de pureté :98.8%Couleur et forme :SolidMasse moléculaire :820.37Boldenone Undecylenate
CAS :Boldenone Undecylenate (Parenabol) is a synthetic steroid.Formule :C30H44O3Degré de pureté :99.39%Couleur et forme :Light Yellow Oily MatterMasse moléculaire :452.67Ref: TM-T3137
1mg35,00€2mg48,00€5mg52,00€1mL*10mM (DMSO)52,00€10mg85,00€25mg140,00€50mg246,00€100mg396,00€500mg939,00€Triptophenolide
CAS :Triptophenolide (Hypolide) is a compound isolated from Tripterygium wilfordii Hook with anti-inflammatory activity.Formule :C20H24O3Degré de pureté :98.07% - ≥95%Couleur et forme :White PowderMasse moléculaire :312.40AC-262536
CAS :AC-262536 is a selective androgen receptor (SAR) modulator and exhibits potent agonist activity at the androgen receptor.Formule :C18H18N2ODegré de pureté :99.88%Couleur et forme :SolidMasse moléculaire :278.35Ref: TM-T26539
5mg46,00€1mL*10mM (DMSO)49,00€10mg74,00€25mg145,00€50mg240,00€100mg359,00€200mg510,00€Enzalutamide
CAS :Enzalutamide (MDV3100) is an androgen receptor (AR) antagonist (IC50=36 nM in LNCaP).Formule :C21H16F4N4O2SDegré de pureté :99% - 99.93%Couleur et forme :SolidMasse moléculaire :464.44Ref: TM-T6002
5mg48,00€1mL*10mM (DMSO)52,00€10mg56,00€25mg74,00€50mg96,00€100mg154,00€200mg187,00€500mg274,00€RU 58841
CAS :RU 58841 (PSK-3841) is a specific androgen receptor antagonist or anti-androgen; RU 58841(PSK-3841) has a significant effect on hair regrowth.Formule :C17H18F3N3O3Degré de pureté :99.31% - 99.70%Couleur et forme :SolidMasse moléculaire :369.34Ref: TM-T2236
5mg40,00€1mL*10mM (DMSO)48,00€10mg63,00€25mg99,00€50mg130,00€100mg177,00€200mg245,00€500mg371,00€EPI-001
CAS :EPI-001 is an androgen receptor N-terminal domain antagonist with IC50 of ～6 μM and a selective PPAR-gamma modulator.Formule :C21H27ClO5Degré de pureté :99% - 99.67%Couleur et forme :SolidMasse moléculaire :394.89Ref: TM-T6829
2mg34,00€5mg48,00€1mL*10mM (DMSO)49,00€10mg73,00€25mg120,00€50mg192,00€100mg286,00€200mg425,00€Clascoterone
CAS :Clascoterone (CB-03-01) is a new topical and peripherally selective androgen antagonist.Formule :C24H34O5Degré de pureté :99.2% - 99.72%Couleur et forme :SolidMasse moléculaire :402.52DSRM-3716
CAS :Isoquinoline, 5-iodo- (9CI) is a potent and selective inhibitor of SARM1(IC50 = 75 nM) by preventing axonal degeneration and by allowing functional recovery ofFormule :C9H6INDegré de pureté :97.28% - 99.785%Couleur et forme :SolidMasse moléculaire :255.06p,p'-DDE
CAS :p,p'-DDE (p,p'-dichlorodiphenyldichloroethylene) is a metabolite and degradation product of the organochlorine pesticide DDTFormule :C14H8Cl4Degré de pureté :99.68%Couleur et forme :White Crystalline Solid Physical Description White Crystalline Solid Or White Powder (Ntp 1992)Masse moléculaire :318.03CSRM617 hydrochloride
CAS :CSRM617 hydrochloride: selective OC2 inhibitor, Kd 7.43 uM, binds OC2-HOX, induces apoptosis, tolerable in mouse prostate cancer.Formule :C10H14ClN3O5Degré de pureté :99.59%Couleur et forme :SoildMasse moléculaire :291.69LY2452473
CAS :LY2452473 (OPK 88004) is an orally available and selective androgen receptor modulator with potential anticancer activity for the study of prostate cancer.Formule :C22H22N4O2Degré de pureté :99.72%Couleur et forme :SolidMasse moléculaire :374.44Ref: TM-T15804
1mg34,00€5mg67,00€1mL*10mM (DMSO)73,00€10mg96,00€25mg133,00€50mg170,00€100mg253,00€200mg386,00€Masofaniten
CAS :Masofaniten (EPI-7386) is an orally active androgen receptor (AR) inhibitor with antitumor activity for the study of prostate and breast cancer.Formule :C24H24Cl2N4O4SDegré de pureté :98.42% - 98.66%Couleur et forme :SolidMasse moléculaire :535.44Estromustine
CAS :Estromustine, an active metabolite of estramustine phosphate, is used to treat prostate cancer.Formule :C23H29Cl2NO3Couleur et forme :SolidMasse moléculaire :438.39GDC-2992
CAS :GDC-2992 is a selective androgen receptor (AR) degradator that degrades AR and inhibits proliferation in VCaP cells,CRPC.Formule :C45H51ClN8O5Degré de pureté :99.82%Couleur et forme :SoildMasse moléculaire :819.39AR antagonist 6
CAS :AR antagonist 6 (compound 6i), a diphenyl ether androgen receptor (AR) antagonist, binds to the AR with an affinity of 120 nM. It demonstrates low toxicity and effective in vitro activity in the golden Syrian hamster ear model. [19] [1]Formule :C16H12F3NO2Couleur et forme :SolidMasse moléculaire :307.27Procymidone
CAS :Procymidone is a broad-spectrum fungicide that inhibits fungal glycerol triester synthesis, thereby disrupting hyphal growth. androgen receptor (AR) antagonistFormule :C13H11Cl2NO2Degré de pureté :99.86%Couleur et forme :Colorless SolidMasse moléculaire :284.14JNJ-37654032
CAS :JNJ-37654032: orally active, nonsteroidal SARM. Mixed AR agonist/antagonist. Selective for muscle, grows levator ani, max at 3mg/kg, ED(50) 0.8mg/kg.Formule :C11H7Cl2F3N2OCouleur et forme :SolidMasse moléculaire :311.09Androgen receptor antagonist 4
CAS :Compound AT2 is an AR inhibitor with anticancer effects, blocking DHT action and AR nuclear translocation (IC50=0.15μM).Formule :C22H18ClNCouleur et forme :SolidMasse moléculaire :331.84Chlormadinone (free base)
CAS :Chlormadinone: synthetic hormone, treats BPH and PCOS, blocks androgen/estrogen, boosts bone cell growth.Formule :C21H27ClO3Couleur et forme :SolidMasse moléculaire :362.89Bifluranol
CAS :Bifluranol (BX341) has anti-androgenic activity and has shown significant anti-prostatic activity in in vivo studies for the treatment of benign prostaticFormule :C17H18F2O2Degré de pureté :99.86%Couleur et forme :SolidMasse moléculaire :292.32Gumelutamide
CAS :Gumelutamide, a tetrahydropyridopyrimidine compound, functions as both an antiandrogen and an antineoplastic agent by acting as an androgen antagonist.Formule :C22H21ClN6OCouleur et forme :SolidMasse moléculaire :420.89AZD3514
CAS :AZD3514 is a potent and oral androgen receptor downregulator with Ki of 2.2 μM and has ability of reducing AR protein expression.Phase 1.
Formule :C25H32F3N7O2Degré de pureté :98.09%Couleur et forme :SolidMasse moléculaire :519.56Honokiol DCA
CAS :Honokiol DCA inhibits DRP1, enhances respiration via mitochondrial repair, and is active against Vemurafenib-resistant melanoma.Formule :C22H18Cl4O4Couleur et forme :SolidMasse moléculaire :488.19Prochloraz
CAS :Prochloraz: broad-spectrum imidazole fungicide; blocks placental aromatase (IC50=40nM), estrogen/androgen receptors; activates aryl hydrocarbon receptors.Formule :C15H16Cl3N3O2Degré de pureté :99.75% - 99.79%Couleur et forme :Colorless SolidMasse moléculaire :376.67
