Récepteur des androgènes
Le récepteur aux androgènes (AR) est un récepteur hormonal nucléaire activé par la liaison aux androgènes, tels que la testostérone et la dihydrotestostérone. Ce récepteur joue un rôle crucial dans le développement et le maintien des caractéristiques masculines, ainsi que dans la régulation de plusieurs processus physiologiques, notamment la croissance musculaire, la libido et la densité osseuse. Les inhibiteurs du récepteur aux androgènes sont largement étudiés dans le contexte du cancer de la prostate, où la signalisation de l'AR est souvent régulée à la hausse. Chez CymitQuimica, nous offrons une gamme de modulateurs du récepteur aux androgènes de haute qualité pour soutenir vos recherches en endocrinologie, biologie du cancer et régulation hormonale.
207 produits trouvés pour "Récepteur des androgènes"
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MI-136
CAS :<p>MI-136 inhibits expression of androgen receptor (AR) target genes that DHT induced.</p>Formule :C23H21F3N6SDegré de pureté :98.63% - 99.12%Couleur et forme :SolidMasse moléculaire :470.51Apalutamide
CAS :<p>Apalutamide (ARN-509) is a small molecule and androgen receptor (AR) antagonist with potential antineoplastic activity.</p>Formule :C21H15F4N5O2SDegré de pureté :99.03% - 99.91%Couleur et forme :SolidMasse moléculaire :477.43S-23
CAS :<p>S-23 ((S)-3-(4-chloro-3-fluorophenoxy)-N-(4-cyano-3-(trifluoromethyl)phenyl)-2-hydroxy-2-methylpropanamide) is an oral selective androgen receptor modulator (</p>Formule :C18H13ClF4N2O3Degré de pureté :99.55%Couleur et forme :SolidMasse moléculaire :416.75Iprodione
CAS :<p>Iprodione is a fungicide. Iprodione is also used in cannabis testing kits as a component of pesticide mixes.</p>Formule :C13H13Cl2N3O3Degré de pureté :98.82%Couleur et forme :Colorless Crystals Cream To Colorless Odorless PowderMasse moléculaire :330.17Testosterone undecanoate
CAS :<p>Testosterone undecanoate is a metabolite of Testosterone, which is a promising androgen for male hormonal contraception.</p>Formule :C30H48O3Degré de pureté :99.45% - 99.788%Couleur et forme :White Crystalline PowderMasse moléculaire :456.7CLP-3094
CAS :<p>CLP-3094 (2-([2-(4-CHLOROPHENOXY)ETHYL]THIO)-1H-BE) is a potent androgen receptor BF3 (binding function 3) inhibitor.</p>Formule :C15H13ClN2OSDegré de pureté :99.84%Couleur et forme :SolidMasse moléculaire :304.79AC-262536
CAS :<p>AC-262536 is a selective androgen receptor (SAR) modulator and exhibits potent agonist activity at the androgen receptor.</p>Formule :C18H18N2ODegré de pureté :99.88%Couleur et forme :SolidMasse moléculaire :278.35Triptophenolide
CAS :<p>Triptophenolide (Hypolide) is a compound isolated from Tripterygium wilfordii Hook with anti-inflammatory activity.</p>Formule :C20H24O3Degré de pureté :98.07% - ≥95%Couleur et forme :White PowderMasse moléculaire :312.4Boldenone Undecylenate
CAS :<p>Boldenone Undecylenate (Parenabol) is a synthetic steroid.</p>Formule :C30H44O3Degré de pureté :99.39%Couleur et forme :Light Yellow Oily MatterMasse moléculaire :452.67JNJ-63576253 free base
CAS :<p>JNJ-63576253 free base (TRC253) is a potent and orally active full antagonist of androgen receptor (AR). JNJ-63576253 can be used for the research of CRPC.</p>Formule :C23H21F3N6O2SDegré de pureté :98.32%Couleur et forme :SolidMasse moléculaire :502.51Dimethylcurcumin
CAS :<p>Dimethylcurcumin (ASC-J9) (ASC-J9) is an androgen receptor degradation enhancer.</p>Formule :C23H24O6Degré de pureté :97.36% - 98.96%Couleur et forme :SolidMasse moléculaire :396.43Nandrolone phenylpropionate
CAS :<p>Nandrolone phenylpropionate (Nandrolone phenpropionate) is an androgen receptor agonist. It mainly used to treat women with breast cancer and osteoporosis</p>Formule :C27H34O3Degré de pureté :99.2% - 99.46%Couleur et forme :White Or Milky Crystalline PowderMasse moléculaire :406.56JNJ-63576253
CAS :<p>JNJ-63576253 is a Clinical Stage Androgen Receptor Antagonist for F877L Mutant and Wild-Type Castration-Resistant Prostate Cancer (mCRPC).</p>Formule :C23H22ClF3N6O2SDegré de pureté :98.71%Couleur et forme :SolidMasse moléculaire :538.97Ailanthone
CAS :<p>Ailanthone (Δ13-Dehydrochaparrinone) is an effective inhibitor of both full-length androgen receptor (AR) (IC50: 69 nM) and constitutively active truncated AR</p>Formule :C20H24O7Degré de pureté :99.71% - 99.96%Couleur et forme :SolidMasse moléculaire :376.43-(7,7-dimethyl-5-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyridin-2-yl)-1H-indole-7-carbonitrile
CAS :<p>3-[7 ,7- dimethyl-5-oxo -6H-pyrrolo[3,4-b]pyridin-2-yI]-1H-indole-7 -carbonitrile is an androgen receptor modulator.</p>Formule :C18H14N4ODegré de pureté :98.41%Couleur et forme :SolidMasse moléculaire :302.33ARD-2128
CAS :<p>ARD-2128: potent oral PROTAC that degrades AR, curbing prostate cancer growth with no toxicity.</p>Formule :C45H50ClN7O6Degré de pureté :98.8%Couleur et forme :SolidMasse moléculaire :820.372-hydroxy Flutamide
CAS :<p>2-hydroxy Flutamide is competitive inhibition of androgen receptor (AR) for the treatment of prostate cancer</p>Formule :C11H11F3N2O4Degré de pureté :99.45% - 99.82%Couleur et forme :SolidMasse moléculaire :292.21AH-3960
CAS :<p>AH-3960 是一种甲状腺激素受体 1 (PTHR1) 激动剂。</p>Formule :C13H22N4O3Degré de pureté :98.44%Couleur et forme :SolidMasse moléculaire :282.34DSRM-3716
CAS :<p>Isoquinoline, 5-iodo- (9CI) is a potent and selective inhibitor of SARM1(IC50 = 75 nM) by preventing axonal degeneration and by allowing functional recovery of</p>Formule :C9H6INDegré de pureté :97.28% - 99.785%Couleur et forme :SolidMasse moléculaire :255.06Bavdegalutamide
CAS :<p>Bavdegalutamide (ARV-110) is a PROTAC degrader of androgen receptor (AR).</p>Formule :C41H43ClFN9O6Degré de pureté :97.17% - 99.04%Couleur et forme :SolidMasse moléculaire :812.29N-desmethyl Enzalutamide
CAS :<p>N-desmethyl Enzalutamide (N-desmethyl MDV 3100) is the active Enzalutamide metabolite.It is the active metabolite of Enzalutamide.</p>Formule :C20H14F4N4O2SDegré de pureté :99.74%Couleur et forme :SolidMasse moléculaire :450.41Enzalutamide carboxylic acid
CAS :<p>Enzalutamide carboxylic acid is an antagonist of androgen receptor (AR) .</p>Formule :C20H13F4N3O3SDegré de pureté :97.88%Couleur et forme :SolidMasse moléculaire :451.39Clascoterone
CAS :<p>Clascoterone (CB-03-01) is a new topical and peripherally selective androgen antagonist.</p>Formule :C24H34O5Degré de pureté :99.2% - 99.64%Couleur et forme :SolidMasse moléculaire :402.52LY2452473
CAS :<p>LY2452473 (OPK 88004) is an orally available and selective androgen receptor modulator with potential anticancer activity for the study of prostate cancer.</p>Formule :C22H22N4O2Degré de pureté :99.72%Couleur et forme :SolidMasse moléculaire :374.44Masofaniten
CAS :<p>Masofaniten (EPI-7386) is an orally active androgen receptor (AR) inhibitor with antitumor activity for the study of prostate and breast cancer.</p>Formule :C24H24Cl2N4O4SDegré de pureté :98.42% - 98.66%Couleur et forme :SolidMasse moléculaire :535.44AR antagonist 6
CAS :<p>AR antagonist 6 (compound 6i), a diphenyl ether androgen receptor (AR) antagonist, binds to the AR with an affinity of 120 nM. It demonstrates low toxicity and effective in vitro activity in the golden Syrian hamster ear model. [19] [1]</p>Formule :C16H12F3NO2Couleur et forme :SolidMasse moléculaire :307.27GDC-2992
CAS :<p>GDC-2992 is a selective androgen receptor (AR) degradator that degrades AR and inhibits proliferation in VCaP cells,CRPC.</p>Formule :C45H51ClN8O5Degré de pureté :99.82%Couleur et forme :SoildMasse moléculaire :819.39Estromustine
CAS :<p>Estromustine, an active metabolite of estramustine phosphate, is used to treat prostate cancer.</p>Formule :C23H29Cl2NO3Couleur et forme :SolidMasse moléculaire :438.39Procymidone
CAS :<p>Procymidone is a broad-spectrum fungicide that inhibits fungal glycerol triester synthesis, thereby disrupting hyphal growth. androgen receptor (AR) antagonist</p>Formule :C13H11Cl2NO2Degré de pureté :99.86%Couleur et forme :Colorless SolidMasse moléculaire :284.14JNJ-37654032
CAS :<p>JNJ-37654032: orally active, nonsteroidal SARM. Mixed AR agonist/antagonist. Selective for muscle, grows levator ani, max at 3mg/kg, ED(50) 0.8mg/kg.</p>Formule :C11H7Cl2F3N2OCouleur et forme :SolidMasse moléculaire :311.09BMS-564929
CAS :<p>BMS-564929 is an AR agonist that upregulates the expression and activity of fat-producing enzymes, reducing VAT content and lipid levels.</p>Formule :C14H12ClN3O3Degré de pureté :98.17%Couleur et forme :SolidMasse moléculaire :305.72(R)-Bicalutamide
CAS :<p>(R)-Bicalutamide, an AR antagonist with antitumor properties, is crucial in prostate cancer research.</p>Formule :C18H14F4N2O4SCouleur et forme :SolidMasse moléculaire :430.37LG-121071
CAS :<p>LG-121071: oral SARM, high-affinity AR full agonist, Ki=17 nM.</p>Formule :C15H15F3N2ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :296.29Honokiol DCA
CAS :<p>Honokiol DCA inhibits DRP1, enhances respiration via mitochondrial repair, and is active against Vemurafenib-resistant melanoma.</p>Formule :C22H18Cl4O4Couleur et forme :SolidMasse moléculaire :488.19Lubabegron fumarate
CAS :<p>Lubabegron (LY591281, LY488756 fumarate) is a beta-agonist approved in 2018 to lower ammonia in cattle waste, aiding environment and health.</p>Formule :C29H29N3O3SC4H4O4Couleur et forme :SolidMasse moléculaire :557.66Gumelutamide
CAS :<p>Gumelutamide, a tetrahydropyridopyrimidine compound, functions as both an antiandrogen and an antineoplastic agent by acting as an androgen antagonist.</p>Formule :C22H21ClN6OCouleur et forme :SolidMasse moléculaire :420.89TFM-4AS-1
CAS :<p>androgen receptor modulator</p>Formule :C27H33F3N2O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :474.56HG122
CAS :<p>HG122 promotes AR degradation via proteasome, inhibiting castration-resistant prostate cancer.</p>Formule :C15H13N5O5Couleur et forme :SolidMasse moléculaire :343.29Androgen receptor antagonist 4
CAS :<p>Compound AT2 is an AR inhibitor with anticancer effects, blocking DHT action and AR nuclear translocation (IC50=0.15μM).</p>Formule :C22H18ClNCouleur et forme :SolidMasse moléculaire :331.84AZD3514
CAS :<p>AZD3514 is a potent and oral androgen receptor downregulator with Ki of 2.2 μM and has ability of reducing AR protein expression.Phase 1.</p>Formule :C25H32F3N7O2Degré de pureté :98.09%Couleur et forme :SolidMasse moléculaire :519.56AR antagonist 2
CAS :<p>AR antagonist 2 (compound 58) is a potent inhibitor of the androgen receptor (AR) (IC50: 0.95 μM).</p>Formule :C22H17ClFN5O2SCouleur et forme :SolidMasse moléculaire :469.92AR antagonist 5
CAS :<p>Compound 30a, known as AR Antagonist 5, is a selective androgen receptor (AR) antagonist that demonstrates an IC 50 value of 134.8 nM. It exhibits favorable pharmacokinetic properties, characterized by high skin exposure and low plasma exposure [1].</p>Formule :C23H21F3N6O2Couleur et forme :SolidMasse moléculaire :470.45CSRM617
CAS :<p>CSRM617: selective ONECUT2 inhibitor, Kd 7.43 uM, binds OC2-HOX, induces apoptosis, tolerable in mouse prostate cancer model.</p>Formule :C10H13N3O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :255.23MK-4541
CAS :<p>MK-4541: oral, selective AR modulator, blocks 5α-reductase, curbs AR+ prostate cancer growth, effective in mouse model.</p>Formule :C22H31F3N2O3Couleur et forme :SolidMasse moléculaire :428.49(R)-UT-155
CAS :<p>(R)-UT-155 is a selective androgen receptor degrader (SARD) ligand.</p>Formule :C20H15F4N3O2Couleur et forme :SolidMasse moléculaire :405.35Carbazole derivative 1
CAS :<p>Carbazole derivative 1 is used to reduce androgen or oestrogen levels in mammals.</p>Formule :C18H13FN2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :276.31VPC-3033
CAS :<p>VPC-3033 is an antagonist of the androgen receptor. It acts by inhibiting the LNCaP cell line as well as cell lines with the wild-type androgen receptor.</p>Formule :C21H14O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :298.33Androgen receptor antagonist 3
CAS :<p>Androgen receptor antagonist 3 (Compound C18) has anticancer activities that is an antagonist of androgen receptor (AR) (IC 50 = 2.4 μM) [1].</p>Formule :C22H18ClNCouleur et forme :SolidMasse moléculaire :331.84RU 58642
CAS :<p>RU 58642 is an effective systemic antiandrogen for androgen-dependent disorders.</p>Formule :C15H11F3N4O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :336.27VPC-13789
CAS :<p>VPC-13789: potent, selective oral antiandrogen for CRPC with 0.19 μM IC50 in LNCaP cells.</p>Formule :C21H16F3N3OCouleur et forme :SolidMasse moléculaire :383.37
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