Tyrosinase
La tyrosinase est une enzyme impliquée dans la synthèse de la mélanine, le pigment responsable de la couleur de la peau, des cheveux et des yeux. La tyrosinase catalyse l'oxydation de la tyrosine en DOPA puis en DOPAquinone, conduisant à la formation de mélanine. Les inhibiteurs de la tyrosinase sont d'intérêt pour le traitement des troubles de l'hyperpigmentation, et ils sont également utilisés dans l'industrie cosmétique pour réduire la pigmentation de la peau. Chez CymitQuimica, nous offrons une large gamme d'inhibiteurs de la tyrosinase et de réactifs de haute qualité pour soutenir vos recherches en dermatologie, enzymologie et science cosmétique.
71 produits trouvés pour "Tyrosinase"
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KW-2450 Formate
KW-2450 Formate is an IGF-1R/IR tyrosine kinase inhibitor with antitumor effects that acts through inhibition of Aurora A and B kinases.KW-2450 Formate inhibits the growth of TNBC xenografts and induces tetraploid accumulation.Formule :C29H31N5O5SDegré de pureté :99.28%Couleur et forme :SolidMasse moléculaire :561.655-Feruloylquinic acid
CAS :5-Feruloylquinic acid, a potent Sirt1 activator, may aid in developing anti-aging drugs.Formule :C17H20O9Degré de pureté :99.03%Couleur et forme :SolidMasse moléculaire :368.344-Chlorosalicylic acid
CAS :<p>4-Chlorosalicylic acid (4-Chloro-2-hydroxybenzoic acid, 4-chloro salicylic acid) is antimicrobial compositions comprising a metal salt and a benzoic acid analog</p>Formule :C7H5ClO3Degré de pureté :98.59%Couleur et forme :Off-White To Light Beige PowderMasse moléculaire :172.57Flanvotumab
CAS :Flanvotumab (IMC-20D7S) is a humanized antibody targeting TYRP1 with strong antitumor effects via NK cells and ADCC.Degré de pureté :> 95%Couleur et forme :LiquidMasse moléculaire :145.42 kDaArbutin
CAS :Arbutin, a bearberry extract, blocks melanin by inhibiting tyrosinase.Formule :C12H16O7Degré de pureté :99.58% - 99.93%Couleur et forme :Colorless Elongated Prisms From Moist Ethyl Acetate White PowderMasse moléculaire :272.252,3-Dihydroisoginkgetin
CAS :2,3-Dihydroisoginkgetin is a Tyrosinase inhibitor with 36.84% inhibition at 0.1 mM.Formule :C32H24O10Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :568.53hTYR/AbTYR-IN-1
CAS :hTYR/AbTYR-IN-1 is a dual hTYR/AbTYR inhibitor with inhibitory effects on hTYR and AbTYR, with IC50s of 5.4 μM and 3.52 μM, respectively.Formule :C18H20N2O3Degré de pureté :99.73%Couleur et forme :SoildMasse moléculaire :312.36Ac-[Nle4,D-Phe7]-α-MSH (4-10)-NH2
CAS :Ac-[Nle4,D-Phe7]-α-MSH (4-10)-NH2, a melanotropin derivative and melanocyte-stimulating hormone, activates tyrosinase and demonstrates a thermoregulatory effectFormule :C47H64N14O10Couleur et forme :SolidMasse moléculaire :985.1Tyrosinase-IN-34
Tyrosinase-IN-34 (compound 5a), a human tyrosinase inhibitor (IC 50: 3.5 μM), shows promise in regulating melanogenesis and pigmentation.Formule :C19H14BrClN4OCouleur et forme :SolidMasse moléculaire :429.7Tyrosinase
CAS :<p>Tyrosinase (Polyphenol oxidase) is a key rate-limiting enzyme encoded by the TYR gene that controls melanin production and catalyzes tyrosine oxidation.</p>Couleur et forme :SolidPseudostellarin G
CAS :Pseudostellarin G, a naturally occurring cyclo-octapeptide, exhibits inhibitory activity against tyrosinase and suppresses melanin production.Formule :C42H56N8O9Couleur et forme :SolidMasse moléculaire :816.94Tyrosinase-IN-13
Tyrosinase-IN-13 (compound 3c), stemming from Flurbiprofen, acts as a potent non-competitive inhibitor of tyrosinase, exhibiting IC50 and Ki values of 68 μM andFormule :C23H18ClFN4OSDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :452.93Swertiajaponin
CAS :Swertiajaponin possesses antimicrobial activity.Formule :C22H22O11Degré de pureté :99.85%Couleur et forme :SolidMasse moléculaire :462.4Potassium iodide
CAS :Potassium iodide 用于治疗过度活跃的甲状腺，并保护甲状腺免受吞咽或吸入放射性碘的辐射影响。可在意外接触放射性碘后或服用含放射性碘的药物前后使用。Formule :IKCouleur et forme :White Solid CrystallineMasse moléculaire :166.01Tyrosinase-IN-32
Tyrosinase-IN-32 (compound 11), a hydroxamate-based alkaloid extracted from black pepper (Piper nigrum L.), functions as an inhibitor of mushroom tyrosinase. In addition to its inhibitory properties, it exhibits antioxidant activity.Formule :C15H19NO3Couleur et forme :SolidMasse moléculaire :261.32[Asp371]-Tyrosinase (369-377), human
CAS :Tyrosinase (369-377,YMDGTMSQV) originates from tyrosinase and needs TAP and proteosome for cell presentation.Formule :C42H66N10O16S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1031.16Tyrosinase-IN-15
Tyrosinase-IN-15 (Compound 39), with an IC50 of 7.12 μM and a Ki of 11.8 μM, functions as a tyrosinase inhibitor [1].Degré de pureté :98%Couleur et forme :Odour SolidTyrosinase-IN-26
Tyrosinase-IN-26 (compound 13) is a non-competitive inhibitor of tyrosinase, with an IC50 value of 68.86 µM. It is capable of inhibiting melanin production.Formule :C25H24N2O6Masse moléculaire :448.16344Tyrosinase-IN-14
<p>Tyrosinase-IN-14 (compound 7m), a tyrosinase inhibitor, modulates the enzyme's secondary structure to diminish its catalytic function, exhibits low cytotoxicity</p>Formule :C21H13Br2N3O3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :547.22Tyrosinase-IN-40
Tyrosinase-IN-40 (Compound 9r) is a competitive inhibitor of tyrosinase, boasting an IC50 value of 17.02 µM and a Ki value of 14.87 µM. This compound also exhibits antioxidant activity and can be utilized in studies related to melanin.Formule :C34H29N9O10Couleur et forme :SolidMasse moléculaire :723.648Tyrosinase-IN-21
Tyrosinase-IN-21 (compound 3g) is a tyrosinase inhibitor with an IC50 value of 80.93 μM.Formule :C23H20N4O3S2Masse moléculaire :464.09768Diaminopropionoyl tripeptide-33
CAS :Diaminopropionoyl Tripeptide-33 is a bioactive peptide that safeguards skin cells against UVA-induced DNA damage and is utilized as a cosmetic ingredient [1].Formule :C17H27N7O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :425.44Tyrosinase-IN-19
Tyrosinase-IN-19 (compound 9), a competitive tyrosinase inhibitor, exhibits potent antioxidant activities by neutralizing ROS, ABTS+, and DPPH radicals andDegré de pureté :98%Couleur et forme :Odour SolidTyrosinase-IN-36
Tyrosinase-IN-36 is a moderately potent inhibitor of tyrosine, exhibiting an inhibition percentage of 42.75% compared to kojic acid at a concentration of 100 μM and possesses antioxidant activity.Couleur et forme :Odour SolidTyrosinase-IN-38
Tyrosinase-IN-38 (compound 6b) is a competitive inhibitor of tyrosinase, demonstrating an IC50 of 25.82 μM and exhibits antioxidant activity.Couleur et forme :Odour SolidAnti-Tyrosinase/TYR Antibody (7Z445)
Anti-Tyrosinase/TYR Antibody (7Z445) is an antibody targeting Tyrosinase/TYR. Anti-Tyrosinase/TYR Antibody (7Z445) can be used in ELISA, IF.Couleur et forme :Odour LiquidXMD16-5
CAS :XMD16-5 blocks TNK2, linked to advanced lung/prostate cancers and breast cancer metastasis in mice; disrupts signaling in several tumors.Formule :C23H24N6O2Degré de pureté :98.89% - 99.98%Couleur et forme :SolidMasse moléculaire :416.48Ref: TM-T3710
1mg44,00€2mg56,00€5mg90,00€10mg144,00€25mg225,00€50mg415,00€100mg615,00€500mg1.311,00€1mL*10mM (DMSO)90,00€Methyl rosmarinate
CAS :<p>Methyl rosmarinate, from Rabdosia serra, inhibits tyrosinase (IC50: 0.28 mM), α-glucosidase, MMP-1, and has antioxidant, antifungal properties.</p>Formule :C19H18O8Degré de pureté :98.68% - 99.62%Couleur et forme :SolidMasse moléculaire :374.34Deoxyarbutin
CAS :DeoxyArbutin(IC50=50 nM) inhibits tyrosinase activity reversibly.Formule :C11H14O3Degré de pureté :99.04% - 99.88%Couleur et forme :SolidMasse moléculaire :194.23Trifolirhizin
CAS :<p>Trifolirhizin exerts varying degrees of inhibition on tyrosinase-dependent melanin biosynthesis, and therefore, are candidates as skin-whitening agents.</p>Formule :C22H22O10Degré de pureté :98% - 99.67%Couleur et forme :SolidMasse moléculaire :446.4Oxyresveratrol
CAS :1.Formule :C14H12O4Degré de pureté :98.09% - 99.69%Couleur et forme :Yellow SolidMasse moléculaire :244.24Isoastilbin
CAS :Isoastilbin is a dihydroflavonol glycoside compound in Rhizoma Smilacis glabrae and Astragalus membranaceus.Formule :C21H22O11Degré de pureté :99.54% - 99.95%Couleur et forme :SolidMasse moléculaire :450.39Ref: TM-TN1772
1mg111,00€2mg165,00€5mg274,00€10mg406,00€25mg663,00€50mg919,00€100mg1.216,00€1mL*10mM (DMSO)311,00€3-(2,4-Dihydroxyphenyl)propanoic acid
CAS :3-(2,4-Dihydroxyphenyl)propanoic acid (Hydroumbellic acid) is a metabolite that is produced by the metabolism of 3-(2, 4-dihydroxyphenyl)prop-2-enoic acid.Formule :C9H10O4Degré de pureté :98.12%Couleur et forme :SolidMasse moléculaire :182.173,4-Dimethoxyphenol
CAS :3,4-Dimethoxyphenol (4-Hydroxyveratrole) is an active biochemical.Formule :C8H10O3Degré de pureté :98.57%Couleur et forme :Red Crystal PowderMasse moléculaire :154.16Gnetol
CAS :Gnetol inhibits butyrylcholinesterase (IC50: 1.3 μM), tyrosinase, melanin synthesis in B16 cells, and AA-induced platelet aggregation.Formule :C14H12O4Degré de pureté :98.55% - ≥95%Couleur et forme :SolidMasse moléculaire :244.24Glycolic acid
CAS :Glycolic acid is an inhibitor of tyrosinase, suppressing melanin formation,and used in skincare productsFormule :C2H4O3Degré de pureté :97.36%Couleur et forme :Colourless Solid CrystallineMasse moléculaire :76.05Tropolone
CAS :Tropolone, a metal chelator, possesses weak antioxidative and radical-scavenging properties and shows a strong affinity for ferric ionFormule :C7H6O2Degré de pureté :99.89%Couleur et forme :Light Yellow-Cream SolidMasse moléculaire :122.123',4'-Dihydroxyacetophenone
CAS :3',4'-Dihydroxyacetophenone (Qingxintong) is an active constituent of Chinese medicine.Formule :C8H8O3Degré de pureté :99.63% - 99.85%Couleur et forme :Light Yellow To Dark Yellow LiquidMasse moléculaire :152.153-O-Ethyl-L-ascorbic acid
CAS :3-O-Ethyl-L-ascorbic acid is a cosmetic tyrosinase inhibitor with whitening ability and is a stabilized vitamin C derivative.Formule :C8H12O6Degré de pureté :97.35% - 99.99%Couleur et forme :White To Very Pale Yellow Crystalline Powder Solid PowderMasse moléculaire :204.18D-Tyrosine
CAS :D-Tyrosine inhibits melanin production and biofilm formation, promoting biofilm dispersal without hindering bacterial growth.Formule :C9H11NO3Degré de pureté :99.86%Couleur et forme :White CrystalsMasse moléculaire :181.19α-Arbutin
CAS :α-Arbutin (4-hydroxyphenyl-D-lucopyranoside) is a synthetic and functional active ingredient for skin lightening.Formule :C12H16O7Degré de pureté :99.82% - 99.94%Couleur et forme :Solid PowderMasse moléculaire :272.252-Ketoglutaric acid Sodium
CAS :2-Ketoglutaric acid Sodium (AKG) is a key molecule in the TCA cycle.Formule :C5H5NaO5Degré de pureté :97.77%Couleur et forme :SolidMasse moléculaire :168.084-Butylresorcinol
CAS :4-Butylresorcinol (Butylresorcinol) is a potent inhibitor of tyrosinase(IC50 : 11.27 μM), and is used in cosmetics as a depigmenting agent.Formule :C10H14O2Degré de pureté :99.48% - ≥95%Couleur et forme :Light Beige Solid PowderMasse moléculaire :166.22β-Tocopherol
CAS :Beta-Tocopherol has effects on human erythroleukemia cell (HEL) adhesion induced by phorbol 12-myristate 13-acetate (PMA).Cost-effective and quality-assured.Formule :C28H48O2Degré de pureté :99.8% - 99.92%Couleur et forme :SolidMasse moléculaire :416.68Ref: TM-TN1441
1mg48,00€2mg64,00€5mg94,00€10mg153,00€25mg250,00€50mg373,00€100mg538,00€1mL*10mM (DMSO)111,00€2-Hydroxy-4-methoxybenzaldehyde
CAS :<p>2-Hydroxy-4-methoxybenzaldehyde (4-Methoxysalicylaldehyde) is an isomer of Vanillin, and a potent tyrosinase inhibitor, could be used to synthesis Urolithin M7.</p>Formule :C8H8O3Degré de pureté :99.78%Couleur et forme :Colorless Needle-Like CrystalMasse moléculaire :152.15SU 4942
CAS :SU-4942 is a modulator of tyrosine kinase signaling.Formule :C15H10BrNODegré de pureté :99% - 99.32%Couleur et forme :SolidMasse moléculaire :300.15SU5214
CAS :SU5214 is a modulator of tyrosine kinase signal transduction.Formule :C16H13NO2Degré de pureté :99.45% - 99.55%Couleur et forme :SolidMasse moléculaire :251.28lavendustin B
CAS :Lavendustin B inhibits Tyrosine Kinase and HIV-1 integrase-LEDGF/p75 interaction.Formule :C21H19NO5Degré de pureté :95.72%Couleur et forme :Off-White SolidMasse moléculaire :365.38Ref: TM-T4182
1mg42,00€5mg88,00€10mg134,00€25mg283,00€50mg419,00€100mg607,00€200mg1.206,00€1mL*10mM (DMSO)87,00€Benzoyloxypaeoniflorin
CAS :Benzoyloxypaeoniflorin, a natural compound, enhances blood flow by inhibiting platelet aggregation and coagulation.Formule :C30H32O13Degré de pureté :98.52% - 99.96%Couleur et forme :SolidMasse moléculaire :600.57Ref: TM-T4S1658
1mg127,00€5mg298,00€10mg432,00€25mg697,00€50mg938,00€100mg1.293,00€1mL*10mM (DMSO)378,00€Mirificin
CAS :Mirificin (BCP10902) is an active ingredient in Tongmai formula (TMF) which is a well-known Chinese medicinal preparation. Anti-oxidant.Formule :C26H28O13Degré de pureté :99.33% - 99.80%Couleur et forme :SolidMasse moléculaire :548.49Taxifolin
CAS :Taxifolin (Dihydroquercetin) is a flavonoid in many plants such as Taxus chinensis, Siberian larch, Cedrus deodara and so on.Formule :C15H12O7Degré de pureté :94.91% - 98.9%Couleur et forme :Yellowish PowderMasse moléculaire :304.25BENZYLACETONE
CAS :Benzylacetone (4-Phenyl-2-butanone) is an aromatic compound extracted from incense wood. Benzylacetone has appetite-enhancing and exercise-reducing properties.Formule :C10H12ODegré de pureté :98.79%Couleur et forme :Colourless LiquidMasse moléculaire :148.2XMD8-87
CAS :XMD8-87 (ACK1-B19), a TNK2 inhibitor, strongly blocks TNK2 phosphorylation and mutations in tumors.Formule :C24H27N7O2Degré de pureté :98.05% - 99.89%Couleur et forme :SolidMasse moléculaire :445.52Ref: TM-T3709
2mg47,00€5mg73,00€10mg103,00€25mg188,00€50mg306,00€100mg507,00€500mg1.225,00€1mL*10mM (DMSO)88,00€2-Methoxycinnamic acid
CAS :1. 2-Methoxycinnamic acid (o-Methoxycinnamic acid) can enhance inhibition of tyrosinase activity.Formule :C10H10O3Degré de pureté :99.68%Couleur et forme :Light Yellow Crystalline PowderMasse moléculaire :178.18ZAP-180013
CAS :<p>ZAP-180013 is an inhibitor of zeta-chain-associated protein kinase 70 (ZAP70,IC50 : 1.8 μM).</p>Formule :C19H17Cl2N3O4SDegré de pureté :98.89%Couleur et forme :SolidMasse moléculaire :454.33Methyl cinnamate
CAS :<p>Methyl cinnamate, a tyrosinase inhibitor and a flavoring compound, has antimicrobial, antiadipogenic, vasorelaxant, and anti-inflammatory effects.</p>Formule :C10H10O2Degré de pureté :99.88%Couleur et forme :Colorless To Pale Yellow Solid CrystallineMasse moléculaire :162.192-Ketoglutaric acid
CAS :2-Ketoglutaric acid is a reversible inhibitor of tyrosinase (IC50=15 mM). 2-Ketoglutaric acid is an intermediate of the Krebs cycle. High-Quality, Low-Cost!Formule :C5H6O5Degré de pureté :99.28%Couleur et forme :SolidMasse moléculaire :146.1Mulberroside A
CAS :1.Formule :C26H32O14Degré de pureté :99.05% - 99.4%Couleur et forme :SolidMasse moléculaire :568.52Ref: TM-T6S1597
1mg49,00€5mg90,00€10mg144,00€25mg254,00€50mg424,00€100mg613,00€1mL*10mM (DMSO)114,00€(R)-Trolox
CAS :(R)-Trolox is a selective tyrosinase inhibitor used in food, cosmetics, and pharmaceutical products.Formule :C14H18O4Degré de pureté :99.88%Couleur et forme :SolidMasse moléculaire :250.29Tyrosinase
CAS :<p>Copper-containing enzyme that catalyzes the first step in the synthesis of melanin</p>Couleur et forme :PowderTyrosinase
CAS :Tyrosinase (EC 1.14.18.1) is an enzyme that oxydises phenol derivatives (e.g. tyrosine, dopamine). One unit of tyrosinase dissolved in 3mL reaction mixture will cause the absorbance at 280nm to increase by 0.001 in the presence of L-tyrosine at pH 6.5 and 25 °C. L-tyrosine is available here.Lyophilized, from mushroom. Activity ≥1000 unit/mgCouleur et forme :Powder3,4-Dihydroxybenzylamine hydrobromide
CAS :<p>3,4-Dihydroxybenzylamine hydrobromide inhibits DNA polymerase and melanoma growth, varying with tyrosinase activity.</p>Formule :C7H10BrNO2Degré de pureté :98.49%Couleur et forme :Light Beige Crystalline PowderMasse moléculaire :220.06Tyrosinase-IN-7
CAS :Tyrosinase-IN-7 is a small-molecule tyrosinase inhibitor (IC50 1.57 μM) that suppresses melanin activity and cell growth with low cytotoxicity.Formule :C15H10O5Degré de pureté :99%Couleur et forme :SolidMasse moléculaire :270.24Tyrosinase-IN-2
CAS :Tyrosinase-IN-2, a potent tyrosinase inhibitor, may help in skin lightening and food preservation research.Formule :C8H8N4O2SDegré de pureté :99.78%Couleur et forme :SolidMasse moléculaire :224.24Ref: TM-T60278
5mg48,00€10mg71,00€25mg135,00€50mg212,00€100mg340,00€200mg467,00€1mL*10mM (DMSO)49,00€Isobutylamido thiazolyl resorcinol
CAS :Isobutylamido thiazolyl resorcinol is a tyrosinase (Tyrosinase) inhibitor that prevents pigment deposition induced by ultraviolet radiation.Formule :C13H14N2O3SCouleur et forme :SolidMasse moléculaire :278.33Plodicitinib
CAS :Plodicitinib is an inhibitor of Janus tyrosine kinase 3/TEC family kinase, exhibiting anti-inflammatory properties.Formule :C19H22FN7O2Couleur et forme :SolidMasse moléculaire :399.422Tyrosinase-IN-37
CAS :Tyrosinase-IN-37 (Compound 3c) is a potent inhibitor of tyrosinase, with an IC50 value of 1.02 μM, which is 14 times more effective than kojic acid (IC50 of 14.74 μM). This compound effectively prevents the browning of Rosa roxburghii and can also inhibit browning not caused by tyrosinase.Formule :C12H12N6SCouleur et forme :SolidMasse moléculaire :272.33Tyrosinase-IN-35
CAS :Tyrosinase-IN-35 (compound 6g), exhibiting a IC 50 value of 2.09 μM, serves as a more effective inhibitor of human tyrosinase compared to Kojic Acid (IC 50: 16.38 μM). At concentrations of 4 μM and 8 μM, this compound effectively lowers melanin levels in melanoma B16F10 cells in vitro.Formule :C17H15N5OSCouleur et forme :SolidMasse moléculaire :337.40Tyrosinase-IN-33
CAS :Tyrosinase-IN-33 (compound 5), a pyridine-based compound, acts as an effective inhibitor of diphenolase activity in mushroom tyrosinase. It significantly reduces enzyme activity with an IC50 of 9.0 μM.Formule :C19H17NS2Couleur et forme :SolidMasse moléculaire :323.48Tyrosinase-IN-20
CAS :<p>Tyrosinase-IN-20 (compound 6a) acts as a potent Tyrosinase inhibitor, demonstrating an IC 50 value of 28.50 μM [1].</p>Formule :C17H18N2O2SCouleur et forme :SolidMasse moléculaire :314.4Tyrosinase-IN-29
CAS :Tyrosinase-IN-29 (compound 5c) is an effective inhibitor of abTYR tyrosinase, demonstrating an IC50 value of 6.11 μM. It is suitable for further research into the inhibition of excessive skin pigmentation.Formule :C10H9NO2Couleur et forme :SolidMasse moléculaire :175.18
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