Hydroxylase
Les hydroxylases sont une classe d'enzymes qui catalysent l'hydroxylation des substrats, ajoutant souvent des groupes hydroxyles (-OH) à des positions spécifiques au sein des molécules. Ces enzymes sont impliquées dans une grande variété de voies biochimiques, y compris la synthèse d'hormones, les processus de détoxification et le métabolisme des médicaments. Les inhibiteurs et activateurs des hydroxylases sont des outils précieux dans la recherche sur les troubles métaboliques, le métabolisme des médicaments et la régulation hormonale. Chez CymitQuimica, nous offrons une sélection de réactifs pour hydroxylases de haute qualité pour soutenir vos recherches en biochimie, pharmacologie et régulation métabolique.
30 produits trouvés pour "Hydroxylase"
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p-Ethynylphenylalanine hydrochloride
CAS :<p>p-Ethynylphenylalanine hydrochloride (4-Ethynyl-L-phenylalanine HCL) is a novel, potent and specific inhibitor of TPH[1].</p>Formule :C11H12ClNO2Degré de pureté :99.03%Couleur et forme :SolidMasse moléculaire :225.67Fenclonine
CAS :<p>Fenclonine (CP-10188) is a selective and irreversible inhibitor of tryptophan hydroxylase, a rate-limiting enzyme in the biosynthesis of serotonin.</p>Formule :C9H10ClNO2Degré de pureté :98.81% - >99.99%Couleur et forme :Crystals From Methanol White SolidMasse moléculaire :199.63ACT-678689
CAS :<p>ACT-678689 (Compound Example 1.53.4) (Compound Example 1.53.4) is a tryptophan hydroxylase (TPH) inhibitor with an IC50 of 8 nM[1].</p>Formule :C23H22ClFN6O4S2Degré de pureté :99.46%Couleur et forme :SolidMasse moléculaire :565.04Telotristat ethyl
CAS :<p>Telotristat ethyl (LX1606) is a orally-delivered inhibitor of tryptophan hydroxylase that reduces serotonin production.</p>Formule :C27H26ClF3N6O3Degré de pureté :98% - 99.89%Couleur et forme :White SolidMasse moléculaire :574.98TPT-004
<p>TPT-004, a TPH inhibitor, exhibits superior pharmacokinetic and pharmacodynamic properties, and demonstrates efficacy in preclinical models for attenuating</p>Couleur et forme :Odour SolidIOX2-NH2-1
CAS :<p>IOX2-NH2-1 inhibits E. coli EGLN-3 (prolyl hydroxylase) with an IC50 of 0.02–1 μM.</p>Formule :C19H17N3O5Degré de pureté :98.77% - 99.91%Couleur et forme :SoildMasse moléculaire :367.36TPH1-IN-1
<p>TPH1-IN-1 (compound 40) is a xanthine derivative that serves as an inhibitor of tryptophan hydroxylase TPH1, with an IC50 of 110.1 nM.</p>Formule :C21H18N6O4SCouleur et forme :SolidMasse moléculaire :450.47GSK180
CAS :<p>GSK180 is a selective competitive inhibitor of kynurenine 3-monooxygenase (KMO; IC50: ~6 nM), an enzyme involved in tryptophan metabolism.</p>Formule :C10H7Cl2NO4Couleur et forme :SolidMasse moléculaire :276.07Cuprizone
CAS :<p>Cuprizone is a copper chelator.Cuprizone is used to induce schizophrenia in mice.Cuprizone induces oligodendrocyte death and induces a demyelination response.</p>Formule :C14H22N4O2Degré de pureté :≥98%Couleur et forme :SolidMasse moléculaire :278.35Nepicastat hydrochloride
CAS :<p>Nepicastat hydrochloride (RS-25560-197 hydrochloride) is a selective, orally active, dopamine-beta-hydroxylase inhibitor that crosses the blood-brain barrier.</p>Formule :C14H15F2N3S·HClDegré de pureté :98.35% - 99.74%Couleur et forme :SolidMasse moléculaire :331.81FG-2216
CAS :<p>FG-2216 (YM-311) is a HIF-prolyl hydroxylase inhibitor for the PDH2 enzyme; orally bioavailable and induced reversible and significant Epo induction in vivo.</p>Formule :C12H9ClN2O4Degré de pureté :97.1% - >99.99%Couleur et forme :SolidMasse moléculaire :280.66Tetrahydropapaverine hydrochloride
CAS :<p>Tetrahydropapaverine hydrochloride (Norlaudanosine HCl) , an analogue of salsolinol and tetrahydropapaveroline, has neurotoxicity on dopamine neurons.</p>Formule :C20H26ClNO4Degré de pureté :99.08%Couleur et forme :White Crystal PowderMasse moléculaire :379.878Telotristat
CAS :<p>Telotristat, active metabolite of LX1606, is an oral tryptophan hydroxylase inhibitor with potential antiserotonergic effects.</p>Formule :C25H22ClF3N6O3Degré de pureté :99.70%Couleur et forme :SolidMasse moléculaire :546.93Ro 61-8048
CAS :Ro 61-8048 is a potent and selective inhibitor of kynurenine hydroxylase with an IC50 value of 37 nM.Formule :C17H15N3O6S2Degré de pureté :98% - >99.99%Couleur et forme :SolidMasse moléculaire :421.45p-Fluoro-L-phenylalanine
CAS :<p>p-Fluoro-L-phenylalanine: TH substrate, studies enzyme regulation, binds E. coli L-leucine receptor, KD 0.26μM.</p>Formule :C9H10FNO2Degré de pureté :99.63%Couleur et forme :White To Off-White PowderMasse moléculaire :183.18Telotristat Etiprate
CAS :<p>Telotristat Etiprate (LX 1606 Hippurate) is an orally bioavailable, tryptophan hydroxylase (TPH) inhibitor with potential antiserotonergic activity.</p>Formule :C27H26ClF3N6O3·C9H9NO3Degré de pureté :99.21% - 99.83%Couleur et forme :White SolidMasse moléculaire :754.15Mildronate
CAS :<p>Mildronate (Meldonium) is an inhibitor of biosynthesis of L-carnitine by gamma-butyrobetaine (GBB) hydroxylase and as a competitive inhibitor of renal carnitine</p>Formule :C6H14N2O2Degré de pureté :99.94%Couleur et forme :White Crystalline PowderMasse moléculaire :146.19TETRAHYDROPIPERINE
CAS :<p>Tetrahydropiperine (Cosmoperine) is a natural product derived from piperine, can be used to treat convulsion, epilepsy, relieve pain, and control insects.</p>Formule :C17H23NO3Degré de pureté :98.04% - 99.61%Couleur et forme :Off-White Low Melting Solid With Characteristic OdourMasse moléculaire :289.37Nepicastat
CAS :<p>Nepicastat (SYN117) is a potent, BBB-permeable, selective DBH inhibitor with IC50s of 8.5/9 nM in bovine/human.</p>Formule :C14H15F2N3SCouleur et forme :SolidMasse moléculaire :295.35Guanoclor
CAS :<p>Guanoclor (VATENSOL) (INN), also known as guanochlor, is a sympatholytic drug. It is known to bind to non-adrenergic sites in pig kidney membranes.</p>Formule :C9H12Cl2N4ODegré de pureté :98.79%Couleur et forme :SolidMasse moléculaire :263.12SU 10603
CAS :<p>SU 10603 is a specific inhibitor of 17α-hydroxylase (also known as CYP17A1 and P450c17) used to study steroid hormone synthesis.</p>Formule :C15H12ClNODegré de pureté :99.93% - 99.96%Couleur et forme :SolidMasse moléculaire :257.72Phenylthiazolylthiourea
CAS :<p>Phenylthiazolylthiourea ia a dopamine-beta-hydroxylase inhibitor.</p>Formule :C10H9N3S2Couleur et forme :SolidMasse moléculaire :235.33Telotristat besilate
CAS :<p>Telotristat besilate is an inhibitor of tryptophan hydroxylase.</p>Formule :C31H28ClF3N6O6SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :705.11(R)-Nepicastat HCl
CAS :<p>(R)-Nepicastat HCl (RS-25560-198 HCl), R-enantiomer, inhibits bovine/human dopamine-β-hydroxylase (IC50: 25.1/18.3 nM); not affecting other enzymes/receptors.</p>Formule :C14H15F2N3S·HClDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :331.81LP-533401
CAS :<p>LP-533401 is an inhibitor of Tryptophan hydroxylase 1. It is used for regulates serotonin production in the gut.</p>Formule :C27H22F4N4O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :526.48Bupicomide
CAS :<p>Bupicomide is a dopamine β-hydroxylase inhibitor with antihypertensive and vasodilatory activity and may be used in the study of hypertension.</p>Formule :C10H14N2ODegré de pureté :99.84% - >99.99%Couleur et forme :SolidMasse moléculaire :178.23Diethyl-pythiDC
CAS :<p>Diethyl-pythiDC is an collagen prolyl 4-hydroxylase inhibitor.</p>Formule :C14H14N2O4SDegré de pureté :99.98%Couleur et forme :SolidMasse moléculaire :306.34LX-1031
CAS :<p>LX-1031 is an effective inhibitor of tryptophan 5-hydroxylase. LX-1031 decreases serotonin (5-HT) synthesis peripherally.</p>Formule :C28H25F3N4O4Degré de pureté :97.123% - 98.97%Couleur et forme :SolidMasse moléculaire :538.52p-Ethynylphenylalanine
CAS :<p>p-Ethynylphenylalanine (4-Ethynyl-L-phenylalanine), a tryptophan hydroxylase (TPH) inhibitor, is competitive, effective, selective, and reversible, with a Ki of</p>Formule :C11H11NO2Degré de pureté :97.57%Couleur et forme :SolidMasse moléculaire :189.21GSK 366
CAS :GSK 366 is a potent kynurenine-3-monooxygenase (KMO) inhibitor (IC50s: 0.7 nM and 2.3 nM for P. fluorescens-KMO and human KMO).Formule :C17H16ClN3O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :361.78
