Immunologie et Inflammation
Les inhibiteurs en immunologie et inflammation sont des composés qui modulent la réponse immunitaire et les processus inflammatoires. Ces inhibiteurs sont cruciaux pour étudier les mécanismes de la régulation immunitaire, l'auto-immunité et l'inflammation chronique, ainsi que pour développer des traitements pour les maladies inflammatoires, les allergies et les troubles immunitaires. En ciblant des voies clés du système immunitaire, ces inhibiteurs peuvent aider à réduire les réponses immunitaires excessives ou inappropriées. Chez CymitQuimica, nous offrons une large sélection d'inhibiteurs de haute qualité en immunologie et inflammation pour soutenir vos recherches en immunologie, inflammation et développement thérapeutique.
Sous-catégories appartenant à la catégorie "Immunologie et Inflammation"
- RCC(136 produits)
- CXCR(147 produits)
- Paroi cellulaire(5 produits)
- Récepteur IL(113 produits)
- IκB/IKK(61 produits)
- LTR(3 produits)
- MALT(23 produits)
- MRP(6 produits)
- NADPH-oxydase(1 produits)
- NF-κB(445 produits)
- NOD(17 produits)
- NOS(63 produits)
- Nrf2(78 produits)
- PGE Synthase(31 produits)
- ROS(69 produits)
- TGF-beta/Smad(58 produits)
- TLR(66 produits)
- Thioredoxine(12 produits)
- gp120/CD4(4 produits)
Affichez 11 plus de sous-catégories
3035 produits trouvés pour "Immunologie et Inflammation"
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ARC186
<p>ARC186 is a highly potent aptamer that serves as a complement inhibitor by blocking the convertase-catalyzed activation of C5.</p>Couleur et forme :SolidMasse moléculaire :120702.76RDR03785
CAS :<p>The MIF Antagonist IV, RDR 03785 controls the biological activity of MIF. This small molecule/inhibitor is primarily used for Cell Structure applications.</p>Formule :C19H18F3NO4Degré de pureté :98.92%Couleur et forme :SolidMasse moléculaire :381.35Schisanchinin D
CAS :<p>Schisanchinin D is a useful organic compound for research related to life sciences. The catalog number is T125682 and the CAS number is 1614245-13-4.</p>Formule :C23H30O6Couleur et forme :SolidMasse moléculaire :402.48712-Oxo phytodienoic acid
CAS :<p>12-oxo PDA boosts alkaloid production in E. californica, enhances B. dioica tendril curls, and blocks JA-induced cell death in A. fru mutants.</p>Formule :C18H28O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :292.41Mifamurtide TFA
<p>Mifamurtide TFA: muramyl dipeptide analog, boosts immunity, activates macrophages/monocytes, potential osteosarcoma research.</p>Formule :C61H110F3N6O21PCouleur et forme :SolidMasse moléculaire :1351.52Galectin-8N-IN-2
<p>Galectin-8N-IN-2 (compound 2) is an effective selective inhibitor of Galectin-8N, with a Ki value of 74 μM.</p>Couleur et forme :Odour SolidNF-κB-IN-9
<p>NF-κB-IN-9, a nuclear factor kappa B (NF-κB) targeting sonosensitizer with excitation and emission wavelengths (λex/λem) of 489/628 nm, features dual</p>Formule :C62H50N4O4SCouleur et forme :SolidMasse moléculaire :947.15CD22 ligand-1
CAS :<p>CD22 ligand-1 is a potent, selective hCD22 binder (K D 0.335 µM) with potential for B-cell disease research.</p>Formule :C33H34N5NaO10Couleur et forme :SolidMasse moléculaire :683.64Galectin-8-IN-2
CAS :<p>Galectin-8-IN-2 (Compound 10) acts as an inhibitor of galectin-8N [1].</p>Formule :C15H20O7Couleur et forme :SolidMasse moléculaire :312.32Interleukin II (60-70)
<p>Interleukin 2 (IL-2) peptide: NH2-LEU-THR-PHE-LYS-PHE-TYR-MET-PRO-LYS-LYS-ALA-COOH, MW 1373.7, immune cytokine.</p>Formule :C68H104N14O14S1Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1373.7Clivatuzumab
CAS :<p>Clivatuzumab is a humanized anti-myxinomab, which can target the MUC1 epitope highly expressed on the surface of most pancreatic cancer cells, and has a good</p>Degré de pureté :SDS-PAGE:95% SEC-HPLC:99.99%Couleur et forme :LiquidMasse moléculaire :145.42 kDaEritoran
CAS :<p>Eritoran: TLR4 antagonist; shields mice from lethal influenza, EBOV, MARV; reduces granulocytosis, eases cytokine storm.</p>Formule :C66H126N2O19P2Couleur et forme :SolidMasse moléculaire :1313.66Chitohexaose hexahydrochloride
CAS :<p>Chitohexaose hexahydrochloride, a TLR4-inhibiting chitosan derivative, blocks LPS-induced inflammation.</p>Formule :C36H74Cl6N6O25Couleur et forme :SolidMasse moléculaire :1203.71ABTIM3-hum03
<p>ABTIM3-hum03 is a humanized anti-TIM3 blood-brain barrier shuttling monoclonal antibody.</p>Degré de pureté :97.6% (SDS-PAGE); 98.6% (SEC-HPLC) - 97.6% (SDS-PAGE); 98.6% (SEC-HPLC)Couleur et forme :Odour LiquidMaritimetin
CAS :<p>Maritimein, an aurone from Coreopsis tinctoria, has potent antioxidant activity (IC50: 4.12 μM) and is used in cardiovascular research.</p>Formule :C15H10O6Couleur et forme :SolidMasse moléculaire :286.24Ara-F-NAD+
CAS :<p>Ara-F-NAD+, an arabino analogue of NAD + , is a potent, slow-binding CD38 NADase inhibitor, with a K i of 169 nM.</p>Formule :C21H26FN7O13P2Couleur et forme :SolidMasse moléculaire :665.421NH2-UAMC1110 TFA
CAS :<p>NH2-UAMC1110 TFA, a derivative of the fibroblast activation protein (FAP) inhibitor UAMC1110, serves as a precursor in the formation of FAPI-QS, a chelating</p>Formule :C23H24F5N5O5Degré de pureté :99.02%Couleur et forme :SolidMasse moléculaire :545.46CP-289
CAS :<p>CP-289 is a potent C5a receptor antagonist with IC50 of 1 μM.</p>Formule :C30H35ClN2O2Degré de pureté :99.97%Couleur et forme :SoildMasse moléculaire :491.06L 012 sodium salt
CAS :<p>L 012 sodium salt: chemiluminescent probe for oxygen & nitrogen detection; identifies superoxides & Nox inhibitors.</p>Formule :C13H8ClN4NaO2Degré de pureté :98.08% - 98.70%Couleur et forme :SolidMasse moléculaire :310.67TMV-IN-6
<p>TMV-IN-6 (Compound 4g) serves as a novel antiviral and fungicidal agent that impedes tobacco mosaic virus (TMV) assembly, functioning by attachment to TMV coat</p>Formule :C29H27N3OSCouleur et forme :SolidMasse moléculaire :465.613-Methoxycatechol
CAS :<p>3-Methoxycatechol: lignin-based, esophageal carcinogen. 1,2-Dihydroxy-3-methoxybenzene: potent anti-EMCV.</p>Formule :C7H8O3Degré de pureté :99.31%Couleur et forme :SolidMasse moléculaire :140.14Topramezone
CAS :<p>Topramezone is a 4-HPPD inhibitor herbicide for post-emergence weed control in corn.</p>Formule :C16H17N3O5SCouleur et forme :SolidMasse moléculaire :363.39Lonazolac Calcium
CAS :<p>Lonazolac Calcium, a nonsteroidal anti-inflammatory drug (NSAID), is used to treat inflammation and pain.</p>Formule :C34H24CaCl2N4O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :663.56NOD2 agonist 3
<p>NOD2agonist 3 (Compound 5) is an effective NOD2 agonist with an EC50 value of 111.45 nM, demonstrating immunoenhancing properties.</p>Formule :C27H39N3O7Couleur et forme :SolidMasse moléculaire :517.61RIPK1-IN-27
<p>RIPK1-IN-27 (compound 19) is an inhibitor of RIPK1.</p>Formule :C27H28N4O3Couleur et forme :SolidMasse moléculaire :456.544-methyl-6-phenyl-2H-pyranone
CAS :<p>4-methyl-6-phenyl-2H-pyranone from Scutellaria boosts mitochondria, shields astrocytes from peroxide.</p>Formule :C12H10O2Degré de pureté :>99.99%Couleur et forme :SolidMasse moléculaire :186.21MC-ND-18
<p>MC-ND-18 is an ATTEC degrader that facilitates the degradation of NLRP3 via autophagy, exhibiting a DC50 of 125.5 nM in THP-1 cells. It is composed of an NLRP3 ligand, a linker, and an LC3 ligand.</p>Formule :C42H42Br2IN3O9SMasse moléculaire :1049.00532β-Amyrin acetate
CAS :<p>Beta-Amyrin acetate: HMGCR & sEH inhibitor (IC50 3.4 μM), anti-inflammatory, antifungal, antioxidant, anti-hyperlipidemic.</p>Formule :C32H52O2Degré de pureté :99.87%Couleur et forme :SolidMasse moléculaire :468.753-O-(2'E,4'Z-Decadienoyl)ingenol
<p>3-O-(2'E,4'Z-Decadienoyl)ingenol is a useful organic compound for research related to life sciences and the catalog number is T124104.</p>Formule :C30H42O6Couleur et forme :SolidMasse moléculaire :498.66Anti-inflammatory agent 78
<p>Anti-inflammatory agent 78 (compound L-37) is a potent anti-inflammatory agent. It effectively inhibits PGE2, PGE1, COX-2, and COX-1. Additionally, Anti-inflammatory agent 78 suppresses the release of NO in LPS-stimulated RAW 264.7 cell lines.</p>Formule :C19H14ClNO4Masse moléculaire :355.06114PROTAC IRAK4 degrader-11
<p>PROTACIRAK4 degrader-11 (compound 15) is a PROTAC molecule utilizing a Cereblon ligand, achieving a maximal IRAK4 degradation rate of 96.25% in HEK293 cells, with a DC50 value of 2.29 nM.</p>Formule :C41H41F3N8O6Masse moléculaire :798.31012Englumafusp alfa
<p>Englumafusp alfa (CD19-4-1BBL; RO7227166) is a fusion protein combining a CD19-specific antibody domain with trimerized extracellular domains of human 4-1BBL,</p>Couleur et forme :Odour LiquidBMS-986235
CAS :<p>BMS-986235 (LAR-1219), an oral FPR2 agonist, EC50: 0.41 nM (hFPR2), 3.4 nM (mFPR2), may prevent heart failure.</p>Formule :C18H17F2N3O3Degré de pureté :99.85%Couleur et forme :SolidMasse moléculaire :361.34M133 peptide
<p>The M133 peptide is a coronavirus-specific CD4 T cell epitope. In mice infected with the neurotropic coronavirus (strain JHM of mouse hepatitis virus), the M133 peptide demonstrates immunodominance. It activates CD4 T cells by forming an MHC/peptide complex through binding with MHC II molecules, which is recognized by specific TCRs.</p>Formule :C84H130N20O25Masse moléculaire :1818.9516dsVACV-70mer sodium
<p>dsVACV-70mer sodium is a 70 base pair double-stranded oligonucleotide that contains a viral DNA motif derived from vaccinia virus DNA. It effectively induces IFN-β through a STING-dependent mechanism.</p>OVA Peptide (323-339)
CAS :<p>OVA Peptide (323-339) is an immunodominant epitope peptide, MHC class II-restricted T-cell epitope , and a B-cell epitope that is recognized by IgE antibodies.</p>Formule :C74H120N26O25Degré de pureté :99.38%Couleur et forme :SolidMasse moléculaire :1773.9Biotin-labeled ODN 1826 sodium
<p>Biotin-labeled ODN 1826 (sodium), a class B CpG oligodeoxynucleotide (ODN), serves as a TLR9 agonist and facilitates assessment of CpG ODN cellular uptake and</p>Couleur et forme :Odour SolidSuc-Tyr-Val-Ala-Asp-pNA
CAS :<p>Suc-YVAD-pNA, a chromogenic caspase-1 substrate.</p>Formule :C31H38N6O12Couleur et forme :SolidMasse moléculaire :686.675GB1908
<p>GB1908 is a selective oral inhibitor of galectin-1 (galectin-1), with Ki values of 57 nM for human galectin-1 and 72 nM for mouse galectin-1. It demonstrates over 50-fold selectivity for galectin-1 compared to galectin-3. GB1908 can be utilized in lung cancer research.</p>Formule :C18H18Cl2N4O5S2Masse moléculaire :504.00957DOPAL
CAS :<p>DOPAL, a neurotoxic aldehyde from dopamine metabolism, is linked to Parkinson's and can convert to DOPAC or DOPET.</p>Formule :C8H8O3Couleur et forme :SolidMasse moléculaire :152.15β-Interleukin II (44-56)
<p>β-Interleukin II is a peptide with the sequence NH2-ILE-LEU-ASN-GLY-ILE-ASN-ASN-TYR-LYS-ASN-PRO-LYS-LEU-COOH.</p>Formule :C68H113N19O19Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1500.742-Hydroxybenzylamine
CAS :<p>2-Hydroxybenzylamine captures IsoLGs, prevents early atrial fibrillation recurrence post-ablation.</p>Formule :C7H9NODegré de pureté :95.93%Couleur et forme :CoaMasse moléculaire :123.15Damnacanthol
<p>Damnacanthol is a useful organic compound for research related to life sciences and the catalog number is T131609.</p>Formule :C16H12O5Couleur et forme :SolidMasse moléculaire :284.267Siegesbeckialide I
<p>Siegesbeckialide I effectively suppresses LPS-induced NO production in RAW264.7 murine macrophages by directly interacting with IKKα/β.</p>Formule :C20H28O6Couleur et forme :SolidMasse moléculaire :364.43StemRegenin 1 Hydrochloride
CAS :<p>StemRegenin 1 Hydrochloride is an AhR antagonist (IC₅₀ = 127 nM) that inhibits RANKL-induced osteoclast generation and differentiation.</p>Formule :C24H24ClN5OSDegré de pureté :99.94%Couleur et forme :SolidMasse moléculaire :466MC1
<p>MC1, an effective NLRP3 inhibitor, exhibits a KD value of 19.3 nM and is devoid of cytotoxicity. This compound enhances cognitive function without causing adverse effects and exhibits no hepatotoxicity. MC1 holds potential for research in Alzheimer's disease.</p>Formule :C23H23N3O6S2Couleur et forme :SolidMasse moléculaire :501.58ODN 2395
CAS :<p>ODN 2395, a class C oligodeoxynucleotide and TLR9 agonist, serves as a vaccine adjuvant. Its sequence is 5'-tcgtcgttttcggcgc:gcgccg-3' [1].</p>Couleur et forme :SolidMasse moléculaire :7035SARS-CoV-2-IN-39
CAS :<p>SARS-CoV-2-IN-39 is a SARS-CoV-2 inhibitor with an EC50 of 1 μM.</p>Formule :C14H8ClF4NO3Degré de pureté :99.86%Couleur et forme :SoildMasse moléculaire :349.66mPGES-1/5-LOX-IN-1
<p>mPGES-1/5-LOX-IN-1 (compound 3j) is a potent, orally active dual inhibitor of mPGES-1 and 5-LOX, with IC50 values of 0.92 and 1.89 µM, respectively. Additionally, mPGES-1/5-LOX-IN-1 exhibits anti-inflammatory properties.</p>Formule :C20H22N4O6SMasse moléculaire :446.12601(±)-Phrymarolin II
CAS :<p>(±)-Phrymarolin II is a promising class of inhibitors that targets the tobacco mosaic virus, representing a novel approach in plant virus suppression.</p>Formule :C23H22O10Couleur et forme :SolidMasse moléculaire :458.419Calcitriol Impurities D
CAS :<p>Calcitriol Impurities D: Vitamin hormone, promotes cell differentiation, has bone activity, inhibits HIV, and aids in treating AIDS/viral infections.</p>Formule :C28H46O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :430.66UNC9036
<p>UNC9036 is a PROTAC degrader of STING, with a DC50 value of 227 nM. The degradation of STING mediated by UNC9036 is dependent on the proteasomal VHL pathway.</p>Formule :C73H95N17O11SMasse moléculaire :1417.71177Antibiofilm agent-8
<p>Antibiofilm agent-8 (compound Ru2) boosts antibacterial activity under visible light (400-700 nm, 10 J cm-2). It induces oxidative stress by promoting NADH oxidation and reactive oxygen species (ROS) generation, which disrupts the bacterial cell wall.</p>Formule :C35H23ClF6N7PRuMasse moléculaire :823.03887CP-447697
CAS :<p>CP-447697, a lipophilic C5a receptor antagonist, exhibits an IC50 of 31 nM. It is utilized in inflammation research.</p>Formule :C29H26ClF2N3O2SDegré de pureté :99.90%Couleur et forme :SoildMasse moléculaire :554.05Glutaminase C-IN-2
<p>Glutaminase C-IN-2 (compound 11), an allosteric inhibitor of glutaminase C (GAC), exhibits potent inhibitory activity with an IC50 of 10.64 nM.</p>Formule :C24H23N7O2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :473.55TLR8 agonist 2
CAS :<p>TLR8 agonist 2 activates human TLR8 (EC50=3nM), less effective on TLR7 (EC50=33.33μM).</p>Formule :C16H22N8Couleur et forme :SolidMasse moléculaire :326.408STING agonist-31
CAS :<p>STING agonist-31, a potent STING agonist, exhibits EC50 values of 0.24 μM and 39.51 μM for human STING (h-STING) and murine STING (m-STING), respectively,</p>Formule :C43H51N15O6Couleur et forme :SolidMasse moléculaire :873.96HSV-60mer sodium
<p>HSV-60mer sodium is a 60 bp double-stranded oligonucleotide that includes viral DNA motifs from the herpes simplex virus 1 (HSV-1) genome. Transfection of HSV-60mer effectively induces IFN-β in a manner dependent on STING, TBK1, and IFN regulatory factor 3 (IRF3).</p>SMRT peptide
CAS :<p>SMRT peptide, one of the corepressor factors interacting with the BCL6 BTB domain, binds to the BTB domain of BCL6 to enhance its transcriptional repression function. Additionally, SMRT peptide is utilized for studying protein-protein interactions.</p>Formule :C82H142N26O24Couleur et forme :SolidMasse moléculaire :1876.16COX-2/NLRP3-IN-1
<p>COX-2/NLRP3-IN-1 (Compound 6k) is an inhibitor that targets COX-2 and NLRP3, exhibiting an IC50 value of 1.53 μM for COX-2. This compound exerts anti-inflammatory effects by inhibiting the NF-κB/NLRP3 signaling pathway.</p>Formule :C24H19Cl2N5OSMasse moléculaire :495.06874PROTAC IRAK4 degrader-5
CAS :<p>PROTAC IRAK4 degrader-5 is a Cereblon-based IRAK4 degrader.</p>Formule :C41H40F3N11O9Couleur et forme :SolidMasse moléculaire :887.834Ezeprogind
CAS :<p>Ezeprogind, TLR9 inhibitor for Alzheimer's. Affordable Excellence: Reliable Quality You Can Trust</p>Formule :C25H44N6Degré de pureté :99.28%Couleur et forme :SolidMasse moléculaire :428.66Ginger extract
CAS :<p>Ginger extract demonstrates (exhibits) anti-cancer, anti-inflammatory, and chemotherapeutic properties in living organisms (in vivo).</p>Couleur et forme :SolidCAY10512
CAS :<p>CAY10512, a resveratrol analog, is 100x more potent, inhibiting NF-κB with an IC50 of 0.15 μM versus resveratrol's 20 μM.</p>Formule :C15H13FOCouleur et forme :SolidMasse moléculaire :228.266Cartap hydrochloride
CAS :<p>Cartap hydrochloride is an insecticidal derivative. It is used to control chewing and sucking insects on many crops.</p>Formule :C18H33Cl2CuN3O3Couleur et forme :Colorless Crystalline Slightly Hygroscopic Solid CoaMasse moléculaire :473.93(-)-10,11-Dihydroxyfarnesol
CAS :<p>(-)-10,11-Dihydroxyfarnesol, from Cryptomarasmius aucubae, inhibits NO production.</p>Formule :C15H28O3Couleur et forme :SolidMasse moléculaire :256.38Benz-AP
CAS :<p>Benz-AP: potent photosensitizer, creates singlet oxygen, more toxic in low hCES2 cancer cells, generates ROS via TPE to kill tumors.</p>Formule :C20H13NO2Couleur et forme :SolidMasse moléculaire :299.32LC-MI-3
<p>LC-MI-3 is an orally active and potent PROTAC degrader of interleukin-1 receptor-associated kinase 4 (IRAK4), with a DC50 value of 47.3 nM. It effectively inhibits the activation of downstream NF-κB signaling. LC-MI-3 is applicable for research in both acute and chronic inflammatory skin conditions.</p>Formule :C39H36N8O8Masse moléculaire :744.26561DZ-837
<p>DZ-837 is a PROTAC that targets the BCL6 protein. The composition of DZ-837 includes the BCL6 ligand-2, the E3 ubiquitin ligase ligand Thalidomide-4-OH, and a PROTAC Linker. The configuration notably features a conjugate of the E3 ubiquitin ligase ligand and the Linker, designated as 2-(2,6-Dioxopiperidin-3-yl)-4-((2-(2-hydroxyethoxy)ethyl)amino)isoindoline-1,3-dione.</p>Formule :C42H44FN9O7SCouleur et forme :SolidMasse moléculaire :837.92NLRP3-IN-52
<p>NLRP3-IN-52 (compund 1) serves as an inhibitor of NLRP3.</p>Formule :C19H25N5O3Couleur et forme :SolidMasse moléculaire :371.43Ara-F-NAD+ sodium
<p>Ara-F-NAD+ sodium, an arabino analogue of NAD+, serves as a potent, reversible, and slow-binding inhibitor of the CD38 NADase [1] [2].</p>Formule :C21H25FN7NaO13P2Couleur et forme :SolidMasse moléculaire :687.4HPK1-IN-57
<p>HPK1-IN-57 (Compound 10c) is an inhibitor of hematopoietic progenitor kinase 1 (HPK1) with an IC50 of 0.09 nM. It suppresses the activity of HPK1 kinase, inhibits the phosphorylation of downstream adaptor protein SLP76 (IC50 of 33.74 nM), and effectively induces the secretion of the T cell activation marker IL-2 (EC50 of 84.24 nM). HPK1-IN-57 holds promise for research in tumor immunotherapy.</p>Formule :C30H36F2N8O3Couleur et forme :SolidMasse moléculaire :594.655WAY-605471
CAS :<p>WAY-605471 is a AHR antagonist with IC50 of 0.5 - 1 μM.</p>Formule :C14H15NO3S2Degré de pureté :99.62%Couleur et forme :SolidMasse moléculaire :309.4Bifarcept
CAS :<p>Bifarcept, a recombinant antibody targeting the interferon receptor type I (IFN-RI), enhances the serum half-life of IFN-β by facilitating its binding.</p>Couleur et forme :LiquidOVA Peptide(257-264) acetate salt
<p>OVA Peptide(257-264) acetate salt is a Class I (Kb)-restricted epitope of OVA. This octamer peptide is presented by Class I MHC molecule H-2Kb derived from ovalbumin.</p>Formule :C47H78N10O15Masse moléculaire :1022.56481Chitoheptaose heptahydrochloride
CAS :<p>Chitoheptaose heptahydrochloride, a chitosan derivative, enhances wheat growth and photosynthesis, with health-protective traits.</p>Formule :C42H80ClN7O29Couleur et forme :SolidMasse moléculaire :1182.57OATD-02 hydrochloride
<p>OATD-02 hydrochloride is the hydrochloride salt form of OATD-02. It is an orally effective, competitive, reversible, and non-covalent dual inhibitor of Arginase1 and Arginase2. OATD-02 hydrochloride serves as a sustained-release inhibitor that efficiently blocks the activity of intracellular arginases, with IC50 values of 20 nM (hARG1), 39 nM (hARG2), 39 nM (mARG1), and 28 nM (rARG1). It effectively eliminates tumor-induced immunosuppression caused by both types of arginases. This compound is utilized in research studies on melanoma.</p>Couleur et forme :Odour SolidIsosorbide dinitrate
CAS :<p>Isosorbide dinitrate (Isordil) is a vasodilator used in the treatment of angina pectoris.</p>Formule :C6H8N2O8Degré de pureté :99.87%Couleur et forme :Hard Colorless Crystals SolidMasse moléculaire :236.14Porphyra 334
CAS :<p>Porphyra 334 is a mycosporine-like amino acid.</p>Formule :C14H22N2O8Couleur et forme :SolidMasse moléculaire :346.336PSMA-IN-2
CAS :<p>PSMA-IN-2, an inhibitor of PSMA with a K i value of 1.07 nM, exhibits favorable in vivo NIR imaging (λ EM = 1088 nm, λ ex = 808 nm) and is useful for NIRII image-guided tumor resection surgery in PSMA-positive tumor-bearing mice [1].</p>Formule :C54H60N14O18S2Couleur et forme :SolidMasse moléculaire :1257.27Human Immunoglobulin M
<p>Human Immunoglobulin M (IgM) is an antibody secreted by the adaptive immune system in response to foreign antigens. It is a primary type of immunoglobulin released into circulation during the early stages of the primary antibody response. Human Immunoglobulin M forms a pentamer comprising five IgG equivalents, with 10 Fab fragments, allowing for 10 antigen binding sites. Additionally, Human Immunoglobulin M acts as a complement (complement) activator.</p>Couleur et forme :Odour SolidMitoquinol
CAS :<p>Mitoquinol is a mitochondria-targeted antioxidant used in the study of cardiovascular disease by modulating the mitochondrial antioxidant defense system.</p>Formule :C38H49O7PSDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :680.83UNC8900
<p>UNC8900 is a VHL-recruiting STINGPROTAC degrader with a DC50 of 0.924 μM. It is applicable for the study of bacterial and viral infections.</p>Formule :C75H99N17O15SMasse moléculaire :1509.72273RDR 02308
CAS :<p>RDR 02308 is a TLR4-MyD88 binding inhibitor that inhibits full-length β-lactamase [1] .</p>Formule :C19H15N3O3Couleur et forme :SolidMasse moléculaire :333.34TMX-201
CAS :<p>TMX-201: TLR7 ligand-phospholipid with potent immune-boosting effect; for breast cancer & melanoma study.</p>Formule :C57H93N6O12PCouleur et forme :SolidMasse moléculaire :1085.36ADU-S100 disodium salt
CAS :<p>ADU-S100 (MIW815) disodium salt is an activator of stimulator of interferon genes (STING).</p>Formule :C20H22N10Na2O10P2S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :734.51POT-4 acetate
<p>POT-4 acetate inhibits Complement C3 activation. POT-4 acetate can be used for studies about age-related macular degeneration.</p>Formule :C74H106N22O20S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1687.9Z-VRPR-FMK TFA
<p>Z-VRPR-FMK (TFA), a tetrapeptide, irreversibly inhibits MALT1, protecting against influenza A.</p>Formule :C33H50F4N10O8Couleur et forme :SolidMasse moléculaire :790.81ZM640
<p>ZM640 is an NLRP3 inhibitor that promotes IL-1β release mediated by NLRP3 inflammasome activation in THP-1 cells. It demonstrates low cytotoxicity.</p>Formule :C28H36F3NO8SMasse moléculaire :603.21137HNGF6A
CAS :<p>increases glucose stimulated insulin secretion and glucose metabolism</p>Formule :C112H198N34O31S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :2581.11InsB (9-23)
CAS :<p>InsB (9-23) (InsulinB chain (9-23)) is an insulin B chain peptide capable of binding to the class II major histocompatibility complex (MHC) allele I-Ag7. It holds potential for research into various autoimmune diseases, including type 1 diabetes.</p>Formule :C72H116N20O22SMasse moléculaire :1645.88Pegaldesleukin
CAS :<p>Pegaldesleukin, a PEG-IL2 conjugate, exhibits antiviral properties, potentially slowing HIV progression, preserving immune function.</p>Couleur et forme :LiquidPSMA-trillium
CAS :<p>PSMA-trillium is a PSMA-targeting compound comprising a PSMA-targeting molecule (PSMA binding agent), a Macropa chelator, and a pharmacokinetics-modulating group (PK modulator). It acts as the non-radioactive variant of Actinium-225-PSMA-Trillium (BAY 3563254), boasting enhanced PSMA targeting and pharmacokinetic properties. PSMA-trillium can bind with Ac through either the Macropa chelator or the radioactive isotope Actinium-225. Actinium-225-PSMA-Trillium effectively inhibits metastatic castration-resistant prostate cancer (mCRPC).</p>Formule :C106H156IN17O34SMasse moléculaire :2371.44M-TriDAP TFA
<p>M-TriDAP (N-Acetylmuramyl-L-Ala-γ-D-Glu-meso-diaminopimelic acid) TFA is a bioactive peptide that functions as an agonist for NOD1/2.</p>Formule :C26H43N5O15·xC2HF3O2hSTING activator-1
<p>hSTING activator-1 (Compound 68) is a STING agonist capable of effectively activating various human STING variants (R232, H232, HAQ), with EC50 values of 56 nM, 89 nM, and 51 nM, respectively. This compound activates the type I interferon pathway by directly binding to the STING protein and stabilizing its conformation, which leads to downstream IRF3 phosphorylation and cytokine release. hSTING activator-1 also demonstrates potential in cancer research by inhibiting fibrosarcoma tumor growth.</p>Couleur et forme :Odour SolidRedaporfin
CAS :<p>Redaporfin (F-2BMet, LUZ-11) is a PDT cancer photosensitizer; 83% of mice had tumor regression with 1.5 mg/kg and 74 J/cm² light.</p>Formule :C48H38F8N8O8S4Couleur et forme :SolidMasse moléculaire :1135.11FITC-labeled ODN 1668 sodium
<p>FITC-labeled ODN 1668 (sodium), a class B CpG oligodeoxynucleotide (ODN), functions as a TLR9 agonist.</p>Couleur et forme :Odour SolidNLRP3-IN-73
<p>NLRP3-IN-73 (W16) is an orally bioavailable inhibitor that disrupts the assembly of the NLRP3 inflammasome, exhibiting an IC50 value of 0.18 μM for the NLRP3/IL-1β pathway.</p>Couleur et forme :Odour SolidBiotin-labeled ODN TTAGGG sodium
<p>Biotin-labeled ODN TTAGGG (sodium) is an inhibitory oligonucleotide (ODN) that functions as an antagonist to TLR9, AIM2, and cGAS.</p>Couleur et forme :Odour SolidCDD-3290
<p>CDD-3290 (Compound 20) is an inhibitor of prostate-specific antigen (PSA) with a Ki value of 216 nM. This compound also exhibits inhibitory effects on α-chymotrypsin and elastase.</p>Couleur et forme :Odour Solid
