Immunologie et Inflammation
Les inhibiteurs en immunologie et inflammation sont des composés qui modulent la réponse immunitaire et les processus inflammatoires. Ces inhibiteurs sont cruciaux pour étudier les mécanismes de la régulation immunitaire, l'auto-immunité et l'inflammation chronique, ainsi que pour développer des traitements pour les maladies inflammatoires, les allergies et les troubles immunitaires. En ciblant des voies clés du système immunitaire, ces inhibiteurs peuvent aider à réduire les réponses immunitaires excessives ou inappropriées. Chez CymitQuimica, nous offrons une large sélection d'inhibiteurs de haute qualité en immunologie et inflammation pour soutenir vos recherches en immunologie, inflammation et développement thérapeutique.
Sous-catégories appartenant à la catégorie "Immunologie et Inflammation"
- RCC(136 produits)
- CXCR(147 produits)
- Paroi cellulaire(5 produits)
- Récepteur IL(113 produits)
- IκB/IKK(61 produits)
- LTR(3 produits)
- MALT(23 produits)
- MRP(6 produits)
- NADPH-oxydase(1 produits)
- NF-κB(445 produits)
- NOD(17 produits)
- NOS(63 produits)
- Nrf2(78 produits)
- PGE Synthase(31 produits)
- ROS(69 produits)
- TGF-beta/Smad(58 produits)
- TLR(66 produits)
- Thioredoxine(12 produits)
- gp120/CD4(4 produits)
Affichez 11 plus de sous-catégories
3035 produits trouvés pour "Immunologie et Inflammation"
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Veledimex (S enantiomer)
CAS :<p>Veledimex S is the oral S enantiomer of a gene therapy promoter activator and CYP3A4/5 inhibitor.</p>Formule :C27H38N2O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :438.6PNRI-299
CAS :<p>PNRI-299 is a selective inhibitor of AP-1 transcription(IC50 of 20 uM ).</p>Formule :C21H15N5O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :401.37CD73-IN-1
CAS :<p>CD73-IN-1 is a CD73 inhibitor with anticancer activity.</p>Formule :C18H17N3O4SDegré de pureté :99.46% - 99.46%Couleur et forme :SolidMasse moléculaire :371.41TMV-IN-1
CAS :<p>TMV-IN-1: a chalcone inhibits TMV with EC50s of 70.7 and 60.8 μg/mL, applicable in infection and tumor studies.</p>Formule :C28H26O4Couleur et forme :SolidMasse moléculaire :426.5TLR7/8 agonist 6
CAS :<p>Compound 4: Imidazoquinoline, potent TLR7/8 agonist, IC50: 0.18μM (TLR7), 5.34μM (TLR8).</p>Formule :C24H27N5O2Couleur et forme :SolidMasse moléculaire :417.5Tin(IV) mesoporphyrin IX dichloride
CAS :<p>Tin(IV) mesoporphyrin IX dichloride (Stannsoporfin) is an effective heme oxygenase (HO) inhibitor used for the treatment of hyperbilirubinemia.</p>Formule :C34H36Cl2N4O4SnDegré de pureté :99.82%Couleur et forme :SolidMasse moléculaire :754.29LY 178002
CAS :<p>LY 178002 inhibits 5-LPO (IC50: 0.6 μM), PLA2, and LTB4 production; weak on cyclooxygenase.</p>Formule :C18H25NO2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :319.46APC-0576
CAS :<p>APC-0576, an (S,S)-isomer, blocks NF-kappaB gene activation and may reduce inflammation in human cells.</p>Formule :C23H27N3O3Couleur et forme :SolidMasse moléculaire :393.48ADU-S100 ammonium salt
CAS :<p>ADU-S100 ammonium salt is an activator of stimulator of interferon genes (STING).Cost-effective and quality-assured.</p>Formule :C20H30N12O10P2S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :724.6COX-2-IN-20
CAS :<p>COX-2-IN-20 (Compound 5d) is a selective and orally active inhibitor of COX-2 (IC 50 = 17.9 nM) with anti-inflammatory activity [1].</p>Formule :C11H9ClFN3O2Couleur et forme :SolidMasse moléculaire :269.66MitoTEMPOL
CAS :<p>MitoTEMPOL is a mitochondria-targeted antioxidant that prevents septal dysfunction by reversing sepsis-induced decreases in mitochondrial function.</p>Formule :C32H42BrNO2PCouleur et forme :SolidMasse moléculaire :583.56NLRP3-IN-13
CAS :<p>NLRP3-IN-13 is an NLRP3 inhibitor that inhibits NLRP3-associated inflammation.NLRP3-IN-13 can be used in the study of neurological disorders and inflammation.</p>Formule :C19H15N3O3SDegré de pureté :99.16%Couleur et forme :SolidMasse moléculaire :365.41C5aR-IN-2
CAS :<p>C5aR-IN-2, a potent C5aR inhibitor, shows promise for researching inflammatory diseases.</p>Formule :C36H40FN5O2Couleur et forme :SolidMasse moléculaire :593.73Keap1-Nrf2-IN-13
CAS :<p>Keap1-Nrf2-IN-13 is a PPI inhibitor (IC50: 0.15 μM) that binds Keap1 strongly, useful for oxidative stress and inflammation research.</p>Formule :C28H32N2O10S2Couleur et forme :SolidMasse moléculaire :620.69c-di-AMP
CAS :<p>c-di-AMP (Cyclic diadenylate) is a STING agonist. It binds to the transmembrane protein STING thereby activating the TBK3-IRF3 signaling pathway.</p>Formule :C20H24N10O12P2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :658.41BC12-4
CAS :<p>BC12-4 is a novel potent inhibitor of IL-2 secretion, it has potent immunomodulatory activity.</p>Formule :C19H14N2O3Couleur et forme :SolidMasse moléculaire :318.33STING modulator-4
CAS :<p>STING modulator-4: competitive, Ki=0.0933 μM (R232H STING), EC50 >10 μM (p-IRF3, THP-1 cells).</p>Formule :C17H18N8OCouleur et forme :SolidMasse moléculaire :350.38L-Kynurenine sulfate
CAS :<p>L-Kynurenine sulfate activates AHR, leading naive T cells to anti-inflammatory Treg phenotype.</p>Formule :C10H14N2O7SCouleur et forme :SolidMasse moléculaire :306.29GCPII-IN-1 TFA
CAS :<p>GCPII-IN-1 TFA (compound 2) is an inhibitor scaffold for glutamate carboxypeptidase II (GCPII, PSMA) with a Ki of 44.3±2.4 nM for use in prostate cancer.</p>Formule :C14H22F3N3O9Couleur et forme :SoildMasse moléculaire :433.34OPC-163493
CAS :<p>OPC-163493 is an orally active, liver-targeted mitochondrial uncoupling agent that diminishes Δψ (delta psi) and mitochondrial ROS (reactive oxygen species)</p>Formule :C14H8F3N5SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :335.31HPGDS inhibitor 3
CAS :<p>HPGDS inhibitor 3: oral, potent (IC50=9.4 nM; EC50=42 nM), selective, no CNS toxicity, good pharmacokinetics, anti-inflammatory.</p>Formule :C21H27N3O2Couleur et forme :SolidMasse moléculaire :353.46IRAK4-IN-17
CAS :<p>IRAK4-IN-17 is a potent IRAK4 inhibitor with a 1.3 nM IC50, key for DLBCL research.</p>Formule :C17H20F2N8OCouleur et forme :SolidMasse moléculaire :390.39T-5342126
CAS :<p>T-5342126: TLR4 antagonist, lowers LPS-induced NO in cells (IC50=27.8 μM) & cytokines in blood, cuts ethanol intake & Iba1 in mice.</p>Formule :C25H32ClN3O3Couleur et forme :SolidMasse moléculaire :457.99CAY10575
CAS :<p>CAY10575 (IKK2-IN-3) is a potent IKK2 inhibitor with potential anti-inflammatory activity for the study of inflammatory and endocrine diseases.</p>Formule :C22H21N3O6S2Couleur et forme :SolidMasse moléculaire :487.55Nω-Propyl-L-arginine hydrochloride
CAS :<p>Highly selective and potent inhibitor of nNOS (Ki = 57 nM). Displays 3158-fold and 149-fold selectivity over iNOS and eNOS respectively. Hypotensive in vivo.</p>Formule :C9H21ClN4O2Couleur et forme :SolidMasse moléculaire :252.74NLRP3-IN-16
CAS :<p>NLRP3-IN-16: potent NLRP3 inflammasome inhibitor; IC50=0.065μM; curbs IL-1β; used in inflammation studies.</p>Formule :C25H25NO5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :419.478A8
CAS :<p>8A8 is a potent NO inhibitor with proinflammatory factor properties, exhibiting an IC50 of 4.7 μM.</p>Formule :C36H37BrClN5O9Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :799.06IMD-biphenylB
CAS :<p>IMD-biphenylB: Potent NF-κB inhibitor, curbs tumor growth with low inflammation and toxicity.</p>Formule :C35H33N5O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :571.67STING agonist-30
CAS :<p>STING agonist-30 is a STING agonist that stimulates STING-dependent immune activation and inhibits HSV, rotavirus and SARS-CoV-2.</p>Formule :C15H16N4O8Degré de pureté :98.80%Couleur et forme :SolidMasse moléculaire :380.31CD38 inhibitor 3
CAS :<p>CD38 Inhibitor 3 (compound 1), with an IC50 of 11 nM, is a potent agent that enhances mitochondrial biogenesis, diminishes lactate levels, and augments both NAD</p>Formule :C16H14F3N7O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :409.32NLRP3-IN-20
CAS :<p>NLRP3-IN-20 (compound 11) is an orally administered inhibitor targeting the NLRP3 inflammasome, exhibiting potent inhibition with an IC50 of 25 nM against IL-1β</p>Formule :C22H27N3O3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :413.53iNOS inhibitor-10
CAS :<p>iNOS Inhibitor-10, with an IC50 of 65 nM, exhibits antiproliferative effects on triple-negative breast cancer cells [1].</p>Formule :C22H23N3O2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :393.5COX-2-IN-32
CAS :<p>COX-2-IN-32 (Compound 2f) is a dual inhibitor of iNOS and COX-2, known to downregulate NF-κB expression.</p>Formule :C25H24O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :420.45SZM679
<p>SZM679: Oral RIPK1 inhibitor, Kd 8.6 nM, weak RIPK3 affinity (>5000 nM). Reduces inflammation, Tau phosphorylation in AD research.</p>Formule :C27H18F5N3O5SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :591.51Eltrombopag methyl ester
CAS :<p>Eltrombopag methyl ester, a Tpo receptor agonist derivative, boosts platelet production for thrombocytopenia research.</p>Formule :C26H24N4O4Couleur et forme :SolidMasse moléculaire :456.49IMD-catechol
CAS :<p>IMD-catechol: an imidazoquinolinone-based dimer with NF-κB activity; improves CT26 cancer treatment, low toxicity.</p>Formule :C31H34N6O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :538.64NLRP3-IN-19
CAS :<p>JT001 (NLRP3-IN-19) is a potent, specific, and orally active NLRP3 inhibitor that impedes the assembly of the NLRP3 inflammasome.</p>Formule :C19H22N4O4SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :402.47NF-κB-IN-8
CAS :<p>NF-κB-IN-8 is a competitive antagonist of LPS for MD-2 binding, and it impedes the expression of inflammatory factors by engaging MD-2.</p>Formule :C24H21N3O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :399.44IMD-biphenylA
CAS :<p>IMD-biphenylA, a novel imidazoquinolinone-based dimer, functions as an NF-κB immunomodulator and enhances the adjuvant properties of small molecule immune</p>Formule :C35H33N5O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :555.67NF-κB-IN-11
CAS :<p>NF-κB-IN-11 (Compound 3i) is an inhibitor of NF-κB, effectively blocking TNF-α-induced NF-κB pathway activation and the nuclear translocation of NF-κB.</p>Formule :C19H18O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :326.34Nrf2 activator-4
CAS :<p>Nrf2 activator-4 is an Nrf2 activator for the treatment of fatty liver disease associated with metabolic dysfunction in humans.</p>Formule :C23H24ClF3N2O3Degré de pureté :98.53%Couleur et forme :SolidMasse moléculaire :468.9Cyclic-di-GMP diammonium
CAS :<p>C-di-GMP diammonium activates STING, regulates biofilms, motility, and virulence in bacteria.</p>Formule :C20H30N12O14P2Couleur et forme :SolidMasse moléculaire :724.47CL264
CAS :<p>CL264, a selective agonist of TLR7, can be used in studies about innate immune signals.</p>Formule :C19H23N7O4Degré de pureté :98.01%Couleur et forme :SolidMasse moléculaire :413.43Tyrosinase-IN-12
CAS :<p>Tyrosinase-IN-12(Non-competitive tyrosinase inhibitor) is a potent non-competitive tyrosinase inhibitor with an IC50 of 49.33 ± 2.64 µM and a Ki of 31.25 ± 0.25</p>Formule :C16H12ClN3SDegré de pureté :99.2%Couleur et forme :SoildMasse moléculaire :313.8NOS-IN-3
CAS :<p>NOS-IN-3: potent, selective iNOS inhibitor; IC50 of 4.6 µM; spares eNOS; low toxicity; potential for septic shock treatment.</p>Formule :C10H15N3OCouleur et forme :SolidMasse moléculaire :193.25Isoandrographolide
CAS :<p>Isoandrographolide induces cell differentiation, protects the liver, blocks NLRP3, and reduces silicosis in mice.</p>Formule :C20H30O5Couleur et forme :SolidMasse moléculaire :350.45AN-3485
CAS :<p>AN-3485 is a Toll-Like Receptor(TLR) inhibitor (IC50s: 18 to 580 nM).</p>Formule :C14H13BClNO3Couleur et forme :SolidMasse moléculaire :289.52PHA-408
CAS :<p>PHA-408 is a novel potent, highly selective and ATP-competitive inhibitor of IKB kinase-2.</p>Formule :C29H27ClFN7O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :560.02STING Agonist 1a
CAS :<p>STING agonist 1a activates STING, induces IRF-SEAP, IFN-β, IL-6, CXCL10 (EC50=16.77 µM); effects reversed by STING KO/inhibitor H-151.</p>Formule :C19H11Cl2N5OCouleur et forme :SolidMasse moléculaire :396.23BI605906
CAS :<p>BI605906 is an IKKβ inhibitor that can be used to study inflammatory skin diseases such as psoriasis.</p>Formule :C17H22F2N4O3S2Degré de pureté :97.14%Couleur et forme :SolidMasse moléculaire :432.51DHMEQ racemate
CAS :<p>DHMEQ racemate is an NF-κB inhibitor. The activity of DHMEQ racemate is lower than (-)-DHMEQ.</p>Formule :C13H11NO5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :261.23SNAP 398299
CAS :<p>SNAP 398299 is a Glycopeptide Receptor Type 3 (Gal3) antagonist with anxiolytic and antidepressant-like effects and is used in the study of mood disorders.</p>Formule :C27H24F3N3O2Degré de pureté :97.16%Couleur et forme :SolidMasse moléculaire :479.49(+)-DHMEQ
CAS :<p>(+)-DHMEQ is an antioxidant transcription factor Nrf2 activator. (+)-DHMEQ is the enantiomer of (-)-DHMEQ.</p>Formule :C13H11NO5Couleur et forme :SolidMasse moléculaire :261.23COX-2-IN-16
CAS :<p>COX-2-IN-16: potent, selective oral COX-2 blocker, IC50=102 μM, reduces NO, anti-inflammatory.</p>Formule :C19H12BrN3O2Couleur et forme :SolidMasse moléculaire :394.22QD-394
CAS :<p>QD-394 promotes ROS, impairs GSH/GSSG ratio, and is cytotoxic to pancreatic cancer cells, with synergy with napabucasin.</p>Formule :C19H19N5O2Couleur et forme :SolidMasse moléculaire :349.39Phortress
CAS :<p>Phortress (NSC-710305) is a potent AhR ligand with strong binding affinity, which subsequently triggers the transcription of CYP1A1 and induces antitumor</p>Formule :C20H25Cl2FN4OSDegré de pureté :99.89%Couleur et forme :SolidMasse moléculaire :459.41NLRP3 antagonist 1
CAS :<p>Potential cancer research drug, NLRP3 antagonist 1, targets immune response in macrophages, neutrophils.</p>Formule :C16H18N6OCouleur et forme :SolidMasse moléculaire :310.35AHR antagonist 5
CAS :<p>Potent, oral AHR blocker from WO2018195397; IC50 < 0.5μM; hinders tumor growth with anti-PD-1.</p>Formule :C25H27Cl3FN7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :550.89KIN1400
CAS :<p>KIN1400 activates IRF3, boosts antiviral immunity, stimulates IFNbeta, and inhibits WNV, DV, and HCV.</p>Formule :C24H17F2N3O2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :449.47Tilarginine
CAS :<p>Tilarginine is a nitric oxide synthetase competitive inhibitor.</p>Formule :C7H16N4O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :188.23ARV-393
CAS :<p>ARV-393 is a PROTAC degrader targeting BCL6 orally available. ubiquitin proteasome for diffuse large b-cell lymphoma (DLBCL) and non-Hodgkin's lymphoma (NHL)</p>Formule :C46H53ClFN9O7Degré de pureté :99.96%Couleur et forme :SoildMasse moléculaire :898.42DDX3-IN-2
CAS :<p>DDX3-IN-2 is a potent DDX3 inhibitor with an IC50 of 0.3 μM and shows broad antiviral effects, including against HIV resistance.</p>Formule :C20H23N5OCouleur et forme :SolidMasse moléculaire :349.43TRAF-STOP inhibitor 6877002
CAS :<p>TRAF-STOP 6877002 inhibits CD40-TRAF6, curbing leukocyte recruitment and macrophage activation/proliferation in plaques.</p>Formule :C17H17NODegré de pureté :99.76%Couleur et forme :SolidMasse moléculaire :251.32MIF-IN-2
CAS :<p>MIF-IN-2 is a MIF inhibitor with anticancer activity for the study of cancer and autoimmune diseases.</p>Formule :C14H10ClN3O4Degré de pureté :98.55%Couleur et forme :SolidMasse moléculaire :319.7TBK1/IKKε-IN-4
CAS :<p>TBK1/IKKε-IN-4, a 6-aminopyrazolopyrimidine derivative, serves as a potent, selective inhibitor for TBK1 and IKKε, demonstrating IC50 values of 13 nM and 59 nM</p>Formule :C28H35N7O4Couleur et forme :SolidMasse moléculaire :533.62UC-781
CAS :<p>UC-781, a potent NNRTI, inhibits HIV-1 with a C50 of 5 nM and is stable across pH and temperatures.</p>Formule :C17H18ClNO2SDegré de pureté :92.17%Couleur et forme :SolidMasse moléculaire :335.85DSR-6434
CAS :<p>DSR-6434 is a selective agonist of TLR7 with antitumor effect. DSR-6434 exhibits EC50s of 7.2 nM and 4.6 nM for human and mouse.</p>Formule :C19H28N8O2Degré de pureté :99.78%Couleur et forme :SolidMasse moléculaire :400.48NRP1 antagonist 2
CAS :<p>NRP1 antagonist 2 (Compound 1) is an NRP1 antagonist.</p>Formule :C20H17ClN6OS2Couleur et forme :SolidMasse moléculaire :456.97OXSI-2
CAS :<p>OXSI-2 (Syk Inhibitor) is an inhibitor of Syk with an EC50 of 313 nM and an IC50 of 14 nM.</p>Formule :C18H15N3O3SDegré de pureté :98%Couleur et forme :Dark Orange SolidMasse moléculaire :353.39Thiazolinobutazone
CAS :<p>Thiazolinobutazone is the 2-amino-2-thiazoline salt of phenylbutazone.</p>Formule :C22H26N4O2SCouleur et forme :SolidMasse moléculaire :410.53CB2 modulator 1
CAS :<p>CB2 modulator 1 is a potent CB2 modulator. It can be used for the research for immune disorders, osteoporosis, inflammation, renal ischemia.</p>Formule :C18H19F3N4O2Degré de pureté :99.6%Couleur et forme :SolidMasse moléculaire :380.36COX/5-LO-IN-1
CAS :<p>COX/5-LO-IN-1 is a cyclooxygenase and 5-lipoxygenase (5-LO) inhibitor, and used for inflammatory and allergic disease states.</p>Formule :C16H15FN2O2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :318.37N-α-Tosyl-L-lysine chloromethyl ketone hydrochloride
CAS :<p>N-alpha-Tosyl-L-lysine chloromethyl ketone hydrochloride inhibits trypsin-like proteases and IFN-γ activities.</p>Formule :C14H22Cl2N2O3SDegré de pureté :97.44%Couleur et forme :PowderMasse moléculaire :369.31COX-2-IN-14
CAS :<p>COX-2-IN-14 (2a) is a potent, selective COX-2 inhibitor with high affinity and notable anti-inflammatory effects in mice.</p>Formule :C18H18N4O6Couleur et forme :SolidMasse moléculaire :386.364Hetrombopag
CAS :<p>Hetrombopag: potent thrombopoietin receptor agonist, well tolerated, safe, promising for immune thrombocytopenia research.</p>Formule :C25H22N4O5Couleur et forme :SolidMasse moléculaire :458.47Ppc-1
CAS :<p>Ppc-1 inhibits Porphyromonas gingivalis, uncouples mitochondria, and blocks IL-2, with anti-obesity, antibacterial, anti-inflammatory effects.</p>Formule :C21H25NO4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :355.43S-MTC
CAS :<p>S-MTC is a selective inhibitor of type I nitric oxide synthase.</p>Formule :C7H15N3O2SDegré de pureté :98%Couleur et forme :Off-White Powder / White SolidMasse moléculaire :205.28Nrf2-Activator-12G
CAS :<p>Nrf2-Activator-12G is a potent Nrf-2 activator.</p>Formule :C15H13ClO3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :308.78(-)-Ibuprofenamide
CAS :<p>(-)-Ibuprofenamide is an amide prodrug of Ibuprofen with anti-inflammatory activity.</p>Formule :C13H19NODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :205.3MALT1-IN-8
CAS :<p>MALT1-IN-8: potent MALT1 inhibitor, IC50=2 nM; hinders OCI-LY3 cells, IC50=1.16 μM; anticancer, from patent WO2018165385A1.</p>Formule :C20H15Cl2N7OCouleur et forme :SolidMasse moléculaire :440.29IL-1β-IN-2
CAS :<p>IL-1β-IN-2, a cannabigerol derivative, serves as a potent inhibitor of IL-1β, exhibiting anti-inflammatory and pain-resolving properties [1].</p>Formule :C22H34O2Couleur et forme :SolidMasse moléculaire :330.5CHS-111
CAS :<p>CHS-111 is a benzyl indazole that inhibits O2- generation, fMLP-induced PLD activity (IC50 3.9μM), and disrupts PLD1/Arf6 and RhoA interactions.</p>Formule :C21H18N2ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :314.38AVE-9488
CAS :<p>AVE-9488 is a novel endothelial NO synthase (eNOS) enhancer that upregulates eNOS expression, induces NO production, and may ameliorate portal hypertension.</p>Formule :C16H14FNODegré de pureté :99.87%Couleur et forme :SolidMasse moléculaire :255.29BAY32-5915
CAS :<p>BAY32-5915 is a selective inhibitor of IKKalpha.</p>Formule :C10H7NO3Degré de pureté :96.48% - 97%Couleur et forme :Yellow Crystalline PowderMasse moléculaire :189.17UC-1V150
CAS :<p>UC-1V150: TLR7 agonist, triggers immune response, anti-tumor, precursor for ISAC synthesis.</p>Formule :C16H17N5O4Couleur et forme :SolidMasse moléculaire :343.34YS-121
CAS :<p>YS121 inhibits mPGES-1 (IC50=3.4μM) & 5-LOX (IC50=6.5μM), and lowers PGE2 in A549 cells (EC50=12μM).</p>Formule :C20H26ClN3O2SCouleur et forme :SolidMasse moléculaire :407.96NBC 6
CAS :<p>NLRP3-IN-NBC6: potent NLRP3 inflammasome inhibitor, IC50 574 nM, Ca2+ independent, inhibits inflammasome in THP-1 cells/BMDMs.</p>Formule :C18H16BCl3N2O2Couleur et forme :SolidMasse moléculaire :409.5STING ligand-1
CAS :<p>STING ligand-1 is a lead STING ligand(IC50 of 68 nM for HAQ STING).</p>Formule :C29H27ClFNO5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :523.98FD-IN-1
CAS :<p>FD-IN-1: Factor D inhibitor, IC50=12 nM; blocks FXIa, Tryptase β2 (IC50s: 7.7 μM, 6.5 μM); key in innate immunity.</p>Formule :C23H23NO4Couleur et forme :SolidMasse moléculaire :377.43Anti-inflammatory agent 8
CAS :<p>Anti-inflammatory agent 8 targets COX-2 over COX-1, IC50 of 0.09 nM, orally bioavailable.</p>Formule :C18H15N5OS2Couleur et forme :SolidMasse moléculaire :381.47M62812 free base
CAS :<p>M62812 (free base), a Toll-like receptor 4 (TLR4) signal transduction inhibitor, suppresses activation of endothelial cells and leukocytes and prevents lethal</p>Formule :C13H11N3OSCouleur et forme :SolidMasse moléculaire :257.31iNOS-IN-2
CAS :<p>iNOS-IN-2 (Compound 53) is a potent inducible nitric oxide synthase (iNOS) protein down-regulator.</p>Formule :C25H31NO7Couleur et forme :SolidMasse moléculaire :457.52JAK2/STAT3-IN-1
CAS :<p>JAK2/STAT3-IN-1 is a GP130 inhibitor with anti-tumor effects and can be used to study inflammation, autoimmunity and cancer.</p>Formule :C34H35BrF3N5O2Degré de pureté :97.35%Couleur et forme :SolidMasse moléculaire :682.57(R,1R)-Tenofovir amibufenamide
CAS :<p>(R,1R)-Tenofovir amibufenamide ((R,1R)-HS-10234) can be used as a Tenofovir prodrug, which can be taken orally and has antiviral activity.</p>Formule :C22H31N6O5PDegré de pureté :98.79% - 99.02%Couleur et forme :SolidMasse moléculaire :490.49SARS-CoV-2 nsp13-IN-1
CAS :<p>SARS-CoV-2 nsp13-IN-1 (C1) inhibits nsp13 ssDNA+ATPase (IC50: 6 μM), not ssDNA-ATPase; useful for COVID-19 research.</p>Formule :C27H20N4O2Degré de pureté :99.44%Couleur et forme :SolidMasse moléculaire :432.47Prostaglandin G/H synthase 1 inhibitor
CAS :<p>Prostaglandin G/H synthase 1 inhibitor (CP 74006) is a selective D5D inhibitor with an IC(50) value of 20 nM.</p>Formule :C13H11ClN2ODegré de pureté :99.76%Couleur et forme :SolidMasse moléculaire :246.697-NINA
CAS :<p>non-selective NOS inhibitor</p>Formule :C7H5N3NaO2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :186.12R110
CAS :<p>R110 shows the potential for cancer research that is a potent, competitive MIF2 tautomerase inhibitor (IC 50 = 15 μM) [1].</p>Formule :C15H17ClN2OSCouleur et forme :SolidMasse moléculaire :308.83TLR7 agonist 1
CAS :<p>TLR7 agonist 1 is a selective and oral TLR7 agonist (IC50: 90 nM).</p>Formule :C21H25N5ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :363.46AZD8848
CAS :<p>AZD8848 is a selective antedrug agonist of toll-like receptor 7 (TLR7). It is developed for the research of asthma and allergic rhinitis.</p>Formule :C29H43N7O5Couleur et forme :SolidMasse moléculaire :569.7
