Immunologie et Inflammation
Les inhibiteurs en immunologie et inflammation sont des composés qui modulent la réponse immunitaire et les processus inflammatoires. Ces inhibiteurs sont cruciaux pour étudier les mécanismes de la régulation immunitaire, l'auto-immunité et l'inflammation chronique, ainsi que pour développer des traitements pour les maladies inflammatoires, les allergies et les troubles immunitaires. En ciblant des voies clés du système immunitaire, ces inhibiteurs peuvent aider à réduire les réponses immunitaires excessives ou inappropriées. Chez CymitQuimica, nous offrons une large sélection d'inhibiteurs de haute qualité en immunologie et inflammation pour soutenir vos recherches en immunologie, inflammation et développement thérapeutique.
Sous-catégories appartenant à la catégorie "Immunologie et Inflammation"
- RCC(136 produits)
- CXCR(147 produits)
- Paroi cellulaire(5 produits)
- Récepteur IL(113 produits)
- IκB/IKK(61 produits)
- LTR(3 produits)
- MALT(23 produits)
- MRP(6 produits)
- NADPH-oxydase(1 produits)
- NF-κB(445 produits)
- NOD(17 produits)
- NOS(63 produits)
- Nrf2(78 produits)
- PGE Synthase(31 produits)
- ROS(69 produits)
- TGF-beta/Smad(58 produits)
- TLR(66 produits)
- Thioredoxine(12 produits)
- gp120/CD4(4 produits)
Affichez 11 plus de sous-catégories
3035 produits trouvés pour "Immunologie et Inflammation"
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PF-06426779
CAS :<p>PF-06426779 is a potent and selective inhibitor of interleukin 1 receptor associated kinase 4 (IRAK4) , with an IC 50 of 0.3 nM.</p>Formule :C17H18FN3O4Couleur et forme :SolidMasse moléculaire :347.346Siplizumab
CAS :<p>Siplizumab (MEDI-507), an IgG1 antibody targeting CD2, depletes T cells, may treat psoriasis.</p>Degré de pureté :100% (SEC-HPLC) - > 95%Couleur et forme :LiquidMasse moléculaire :147.24 kDaDovanvetmab
CAS :<p>Dovanvetmab (ZTS-00521505) is an IgG1-κ monoclonal antibody that targets feline interleukin 31 (Felcat IL31), primarily produced in Chinese Hamster Ovary (CHO)</p>Couleur et forme :Liquid3-(2-Hydroxyethyl) thio withaferin A
<p>3-(2-Hydroxyethyl) thio withaferin A, a steroidal lactone, blocks NF-kB, targets vimentin, and inhibits EPCR shedding.</p>Formule :C30H44O7SCouleur et forme :SolidMasse moléculaire :548.73Hispaglabridin A
CAS :<p>Hispaglabridin A, an effective antioxidant, inhibits lipid peroxidation [1].</p>Formule :C25H28O4Couleur et forme :SolidMasse moléculaire :392.49Rucosopasem manganese
CAS :<p>Rucosopasem manganese (GC4711), a selective SOD mimetic, converts superoxide to peroxide for cancer research.</p>Formule :C27H45MnN5O4Couleur et forme :SolidMasse moléculaire :558.626NF-κB-IN-9
<p>NF-κB-IN-9, a nuclear factor kappa B (NF-κB) targeting sonosensitizer with excitation and emission wavelengths (λex/λem) of 489/628 nm, features dual</p>Formule :C62H50N4O4SCouleur et forme :SolidMasse moléculaire :947.15Eritoran Tetrasodium
CAS :<p>Eritoran Tetrasodium, a TLR4 receptor antagonist, is used potentially for the treatment of type 2 diabetes.</p>Formule :C66H122N2Na4O19P2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1401.58IL-17-IN-3
<p>IL-17-IN-3 (compound 11) is an IL-17A inhibitor with an IC50 value of 35 nM. In a rat tolerance study, it showed no adverse reactions when administered at doses up to 300 mg/kg/day for four consecutive days.</p>Formule :C22H25F6N5O3SCouleur et forme :SolidMasse moléculaire :553.521FGT-4
<p>FGT-4 is a chimeric molecule targeting folate receptor β (FR-β) and functions as a TLR7 agonist. It enhances the secretion of iNOS and the pro-inflammatory cytokine IL-6 associated with M1 macrophages and promotes the proliferation of cytotoxic CD8+ T cells. FGT-4 demonstrates antitumor activity in the 4T1 breast cancer mouse model and is applicable for cancer immunotherapy research.</p>Formule :C50H57N11O9S2Couleur et forme :SolidMasse moléculaire :1019.37821AMY-101
CAS :<p>AMY-101 TFA is a C3 complement inhibitor with high affinity (KD: 0.5 nM) and promising anti-inflammatory effects in severe COVID-19.</p>Formule :C83H117N23O18S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1789.11PSB-24000
<p>PSB-24000 (Compound 27) is a selective ecto-5'-nucleotidase (CD73) inhibitor with a Ki value of 563 nM for inhibiting human CD73, and a Ki of 481 nM in membrane-bound CD73 in triple-negative breast cancer cells. It disrupts CD73’s recognition and action on substrate AMP, preventing AMP-induced immunosuppressive and pro-cancer adenosine production. PSB-24000 is promising for cancer research.</p>Couleur et forme :Odour SolidTetrachlorohydroquinone
CAS :<p>TCHQ, a pentachlorophenol metabolite, toxic to trout liver cells, increases ROS, disrupts mitochondria, and causes necrosis in splenocytes. EC50: 1.55 μM.</p>Formule :C6H2Cl4O2Couleur et forme :SolidMasse moléculaire :247.89Lintuzumab
CAS :<p>Lintuzumab (HuM-195) is an uncoupled humanized mouse monoclonal antibody against CD33 with anti-leukemic activity.</p>Degré de pureté :98% (SDS-PAGE); 98.6% (SEC-HPLC) - 98.1% (SDS-PAGE); 98.2% (SEC-HPLC)Couleur et forme :LiquidCD73-IN-17
<p>CD73-IN-17 (compound 19) is an inhibitor of CD73 with an IC50 of 0.1 μM against hCD73. It is applicable in cancer research.</p>Couleur et forme :Odour Solid2-Aminoquinoline
CAS :<p>Compound Fr16621, with CAS No. 580-22-3, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound Fr16621 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.</p>Formule :C9H8N2Couleur et forme :Light Yellow CrystalsMasse moléculaire :144.18EG01377 2HCl
CAS :<p>EG01377 2HCl is a potent, bioavailable and selective inhibitor of neuropilin-1 (NRP1) with a Kd value of 1.32 μM and an IC50 value of 609 nM for both EG01377</p>Formule :C26H32Cl2N6O6S2Degré de pureté :98.91%Couleur et forme :SoildMasse moléculaire :659.6Ginger extract
CAS :<p>Ginger extract demonstrates (exhibits) anti-cancer, anti-inflammatory, and chemotherapeutic properties in living organisms (in vivo).</p>Couleur et forme :SolidIACS-8803 disodium
CAS :<p>IACS-8803 Disodium, a potent cyclic dinucleotide STING agonist, exhibits strong systemic antitumor efficacy [1].</p>Formule :C20H21FN10Na2O9P2S2Couleur et forme :SolidMasse moléculaire :736.50CD19 CAR mRNA
<p>CD19 CAR mRNA expresses a protein for use in CAR-CD19 T cell therapy, targeting B cell antigen for cancer treatment.</p>Couleur et forme :SolidSTING-IN-12
<p>STING-IN-12 (compound Y2) acts as an inhibitor of STING. It suppresses IFNβ gene expression induced by SR717 with an IC50 of 0.75 μM. Additionally, STING-IN-12 inhibits STING pathway activation induced by the STING agonist SR717 in THP1 cells and by MSA-2 in mice.</p>Couleur et forme :Odour SolidMifamurtide sodium
CAS :<p>Mifamurtide sodium is a drug against osteosarcoma, a kind of bone cancer mainly affecting children and young adults. It was approved in Europe in March 2009.</p>Formule :C59H108N6NaO19PDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :1259.48KTX-612
CAS :<p>KTX-612 is a compound that serves as an orally active IRAK4 degrader, exhibiting a DC50 value of 7 nM. It is primarily utilized in oncology research [1].</p>Formule :C46H51F3N8O6Couleur et forme :SolidMasse moléculaire :868.94CDN-A
CAS :<p>CDN-A, a cyclic di-nucleotide, activates immune response & aids in ADC synthesis.</p>Formule :C22H29N11O12P2Couleur et forme :SolidMasse moléculaire :701.48Goflikicept
CAS :<p>Goflikicept (RPH 104) binds/inactivates IL-1ß/α; may research STEMI.</p>Couleur et forme :LiquidSTING agonist-17
CAS :<p>STING agonist-17 (compound 4a) is a highly potent stimulator of the STING pathway, exhibiting an IC 50 of 0.062 nM.</p>Formule :C43H53N13O8Couleur et forme :SolidMasse moléculaire :879.96Melredableukin alfa
CAS :<p>Melredableukin alfa, a human IgG1-κ fused with IL2 mutein, is studied for autoimmune hepatitis and ulcerative colitis.</p>Couleur et forme :LiquidOlendalizumab
CAS :<p>Olendalizumab (ALXN1007) is a humanized antibody targeting C5a for research on COVID-19-related inflammation.</p>Couleur et forme :LiquidPS 1145 dihydrochloride
CAS :<p>IκB kinase (IKK) inhibitor</p>Formule :C17H13Cl3N4ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :395.67STING-IN-14
CAS :<p>STING-IN-14 is a STING inhibitor with an IC50 of 0.6 nM. It effectively suppresses the activation of the IRF pathway in THP1-DualTM cells. This compound is applicable in research related to autoimmune diseases.</p>Formule :C46H43F2N11O5Couleur et forme :SolidMasse moléculaire :867.901ODN D-SL03
CAS :<p>ODN D-SL03, a C class CpG oligonucleotide, stimulates PBMCs, activating B cells, NK cells & monocytes, and can inhibit tumor growth.</p>Couleur et forme :SolidMasse moléculaire :9345Mosnodenvir
CAS :<p>Mosnodenvir is a pan-DENV inhibitor effective against all four serotypes of dengue viruses, with the advantage of being highly potent and orally bioavailable, and blocks viral replication by inhibiting the formation of the complex between NS3 and NS4B.</p>Formule :C26H22ClF3N2O6SDegré de pureté :99.72%Couleur et forme :SoildMasse moléculaire :582.98MJ210
<p>MJ210 is an orally active and blood-brain barrier-permeable modulator of the NF-κB and MAPK pathways, exhibiting neuroprotective properties. In vitro, 5 μM MJ210 can increase the survival rate of rotenone-treated SH-SY5Y cells to 81.9% and reduce levels of ROS. In vivo, 5 mg/kg MJ210 improves motor dysfunction in rat models of Parkinson's disease. MJ210 is useful for research in neurological disorders, including Parkinson's disease.</p>Couleur et forme :Odour SolidBavunalimab
CAS :<p>Bavunalimab: bispecific anti-CTLA-4/LAG-3 antibody, T-cell activator in NSG mice, for cancer research.</p>Couleur et forme :LiquidNLRP3-IN-49
<p>NLRP3-IN-49 (compound Z48) is a potent and specific inhibitor of NLRP3, displaying IC50 values of 0.26 μM in THP-1 cells and 0.21 μM in mouse bone marrow-derived macrophages. It directly binds to the NLRP3 protein with a dissociation constant (Kd) of 1.05 μM, effectively preventing the assembly and activation of the NLRP3 inflammasome, thereby exhibiting anti-inflammatory properties. NLRP3-IN-49 is utilized in the research of inflammatory bowel disease.</p>Couleur et forme :Odour SolidNOD1/2-IN-1
<p>NOD1/2-IN-1 (Compound 18) is a potent RIPK2 inhibitor, demonstrating an IC50 value of 1.4 nM in the ADP-Glo assay. It blocks the production of pro-inflammatory cytokines by inhibiting the NOD1/NOD2 pathway (IC50 values are 18 nM and 170 nM for NOD1 and NOD2, respectively), thereby reducing inflammatory responses. This compound is utilized in research related to colitis.</p>Couleur et forme :Odour SolidIsoxaben
CAS :<p>Isoxaben (EL 107) is a specific inhibitor of cell wall biosynthesis, often used as a herbicide, that inhibits the incorporation of radiolabeled glucose into</p>Formule :C18H24N2O4Degré de pureté :98.84%Couleur et forme :SolidMasse moléculaire :332.39diABZI-4
CAS :<p>DiABZI-4 is an orally active STING agonist that exhibits broad-spectrum antiviral activity. It functions by activating STING to induce the production of pro-inflammatory cytokines and activation of lymphocytes. This action inhibits the replication of Influenza A virus (IAV), SARS-CoV-2, and Human Rhinovirus (HRV), with an EC50 range of 11.8-199 nM.</p>Formule :C40H51Cl2N13O6Couleur et forme :SolidMasse moléculaire :880.821-Ethoxycarbonyl-β-carboline
CAS :<p>1-Ethoxycarbonyl-β-carboline is a natural product for research related to life sciences. The catalog number is TN7072 and the CAS number is 72755-19-2.</p>Formule :C28H23N4O4Couleur et forme :SolidMasse moléculaire :479.516Ladanetin-6-O-β-D-glucopyranoside
CAS :<p>Ladanetin-6-O-β-D-glucopyranoside, an active flavonoid, exhibits antioxidative effects and has potential for research into cardioprotective effects [1].</p>Formule :C22H22O11Couleur et forme :SolidMasse moléculaire :462.4TLR7/8 agonist 12
<p>TLR7/8 agonist 12 (compound 9) is a human TLR7/8 agonist with EC50 values of 11 nM for hTLR7 and 150 nM for hTLR8, indicating its potential for immune modulation.</p>Formule :C29H38N6O3Couleur et forme :SolidMasse moléculaire :518.65E7766 disodium
CAS :<p>E7766 disodium, a macrocycle-bridged STING agonist, exhibits a binding affinity (Kd) of 40 nM, demonstrating potent pan-genotypic and antitumor effects.</p>Formule :C24H26F2N10Na2O8P2S2Couleur et forme :SolidMasse moléculaire :792.58AB-680 ammonium
<p>AB-680: potent, reversible CD73 inhibitor, Ki=4.9 pM, >10,000-fold selectivity vs CD39, anti-tumor.</p>Formule :C20H30ClFN6O9P2Couleur et forme :SolidMasse moléculaire :614.89PMX 205 Trifluoroacetate
<p>PMX 205 Trifluoroacetate is a potent complement C5a receptor ( C5aR ; CD88 ) antagonist.</p>Formule :C47H63F3N10O8Couleur et forme :SolidMasse moléculaire :953.06NHEJ inhibitor-1
<p>NHEJ inhibitor-1 (C2) is a Pt(II) complex that targets DSB repair to combat Cisplatin-resistant NSCLC by hindering Ku70/Rad51 and inducing ROS.</p>Formule :C30H35N7O8PtSCouleur et forme :SolidMasse moléculaire :848.79Sirtuin modulator 2
CAS :<p>Sirtuin modulator 2 (N-(3-(imidazo[2,1-b]thiazol-6-yl)phenyl)-2-methoxybenzamide) exhibits antidiabetic, anti-inflammatory and antitumor activities.</p>Formule :C19H15N3O2SDegré de pureté :99.67%Couleur et forme :SolidMasse moléculaire :349.41NLRP3-IN-75
<p>NLRP3-IN-75 is an orally effective inhibitor of NLRP3, capable of suppressing IL-1β secretion with an IC50 of 23 nM. It selectively inhibits NLRP3 activation by disrupting inflammasome assembly without affecting the assembly of NLRC4 or AIM2 inflammasomes. NLRP3-IN-75 demonstrates excellent anti-inflammatory effects in models of acute peritonitis, diabetic nephropathy, and inflammatory bowel disease (IBD).</p>Couleur et forme :Odour SolidHydroxychloroquine Impurity E
CAS :<p>Hydroxychloroquine Impurity E, a byproduct, can block TLR7/9 and inhibit SARS-CoV-2 in vitro.</p>Formule :C14H17ClN2OCouleur et forme :SolidMasse moléculaire :264.75PMX-53
CAS :<p>PMX-53: MrgX2 agonist; C5aR antagonist; lessens atherosclerotic lesions & metastasis in mice; blocks rat hypernociception.</p>Formule :C47H65N11O7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :896.09ADP-β-S trisodium
<p>ADP-β-S (trisodium) is an analog of ADP and acts as a partial agonist. It can induce human platelet aggregation and inhibit PGE1-stimulated adenylate cyclase.</p>Formule :C10H12N5Na3O9P2SCouleur et forme :SolidMasse moléculaire :508.95241Butan-1-amine hydrochloride
CAS :<p>1-Butylamine hydrochloride,butylamine, a potential agonist of Nrf2/ARE (Nuclear Factor Erythroid 2 Associated Factor 2/Antioxidant Response Element).</p>Formule :C4H12ClNCouleur et forme :SolidMasse moléculaire :109.6Dalutrafusp alfa
CAS :<p>Dalutrafusp alfa (AGEN-1423; GS-1423) is a bifunctional antibody targeting CD73 and TGF-β, components of the immunosuppressive pathway [1].</p>Couleur et forme :LiquidMipeginterferon alfa-2b
CAS :<p>Mipeginterferon alfa-2b, an IFNA2b analogue, has 5 modified amino groups out of 11 and weighs 40 kDa.</p>Couleur et forme :LiquidMurrayafoline A
CAS :<p>Murrayafoline A is a useful organic compound for research related to life sciences. The catalog number is T124835 and the CAS number is 4532-33-6.</p>Formule :C14H13NOCouleur et forme :SolidMasse moléculaire :211.264GSK2831781
<p>GSK2831781 is a human IgG1 monoclonal antibody (mAb) designed to target CD223/LAG3. This compound is applicable in research studies focused on ulcerative colitis. For experimental controls, the recommended isotype control is Human IgG1 kappa.</p>Couleur et forme :Odour LiquidBMS-986179
<p>BMS-986179 is a human monoclonal antibody targeting NT5E/CD73. It inhibits CD73 enzymatic activity both in tumor vasculature and tumor cells. BMS-986179 is applicable for research in advanced solid tumors.</p>Couleur et forme :Odour LiquidNLRP3-IN-74
<p>NLRP3-IN-74 (Compound 11) is an orally active NLRP3 inhibitor with an IC50 of 2.7 μM. It significantly reduces IL-1β release by approximately 90% without affecting TNFα release. NLRP3-IN-74 is applicable in research on diseases such as atherosclerosis and Parkinson's disease.</p>Couleur et forme :Odour SolidNLRP3-IN-48
<p>NLRP3-IN-48 is an inhibitor of NLRP3. It suppresses the activation of the NLRP3 inflammasome by targeting the NLRP3 protein, thereby interfering with the assembly of the NLRP3 inflammasome. Additionally, NLRP3-IN-48 exhibits anti-inflammatory activity in a DSS-induced acute colitis model in mice.</p>Couleur et forme :Odour SolidRIPK1-IN-25
<p>RIPK1-IN-25 (WL8) is a RIPK1 inhibitor with blood-brain barrier permeability, displaying an EC50 of 19.9 nM and a Kd of 25 nM. It is utilized in the research of neurodegenerative diseases.</p>Couleur et forme :Odour SolidEfmarodocokin alfa
CAS :<p>Efmarodocokin alfa, IL-22/IgG4 fusion protein, activates IL-22 pathways, researched for severe COVID-19 pneumonia.</p>Couleur et forme :LiquidBI1543673
<p>BI1543673 is an inhibitor of interleukin-1 receptor-associated kinase 4 (IRAK4). It can diminish inflammatory responses in human lung tissue stimulated by TLR4 and TLR7/8. Additionally, BI1543673 reduces inflammatory signaling in a mouse lung inflammation model induced by LPS.</p>Couleur et forme :Odour SolidNLRP3-IN-51
<p>NLRP3-IN-51 (Compound 3q) is an effective activator of the cholinergic anti-inflammatory pathway (CAP). This compound demonstrates potential for treating gouty arthritis as it inhibits the production of IL-1β in THP-1 cells induced by monosodium urate (MSU). Furthermore, NLRP3-IN-51 suppresses the phosphorylation of NF-κBp65 triggered by MSU without impacting the self-cleavage and activation of NLRP3, pro-caspase 1, or the second messenger caspase-1. Therefore, the initial stage of NLRP3 inhibition by NLRP3-IN-51 occurs through the activation of CAP.</p>Couleur et forme :Odour SolidSTING-IN-6
CAS :<p>STING-IN-6 (compound 50), a potent inhibitor of STING, exhibits a pIC50 value of 8.9, indicating its significant inhibitory capacity.</p>Formule :C46H52N12O6Couleur et forme :SolidMasse moléculaire :868.98Bectumomab
CAS :<p>Bectumomab (IMMU-LL2) is a humanized IgG2a mAb targeting CD22, used in imaging and staging non-Hodgkin's lymphoma.</p>Couleur et forme :LiquidIFN-α Receptor Recognition Peptide 1
CAS :<p>IFN-α Receptor Recognition Peptide 1, associated with receptor interactions, is a peptide of IFN-α.</p>Formule :C35H59N13O12SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :885.99STING agonist-29
CAS :<p>CF511: non-nucleotide, small-molecule STING activator; fights SARS-CoV variants.</p>Formule :C38H44N14O6Couleur et forme :SolidMasse moléculaire :792.85Anticancer agent 15
CAS :<p>Anticancer agent 15 raises ROS, causing necroptosis in melanoma cells.</p>Formule :C35H40Cl2N2O5Couleur et forme :SolidMasse moléculaire :639.61PNT2001
CAS :<p>PNT2001 (LY4181530) is an effective prostate-specific membrane antigen (PSMA) ligand with an IC50 of 3.1 nM. It enhances cellular internalization and, when labeled with 177Lu and 225Ac, is applicable for prostate cancer research.</p>Formule :C85H107N15O32Couleur et forme :SolidMasse moléculaire :1850.84Dazostinag
CAS :<p>Dazostinag (TAK-676) is a STING agonist with anti-cancer properties, used in making ADCs.</p>Formule :C21H22F2N8O10P2S2Couleur et forme :SolidMasse moléculaire :710.52Sacituzumab MMAE
<p>Sacituzumab-MMAE (CHB295) Anti-TROP2 Reference Antibody is produced in CHO cells and consists of a huIgG1 heavy chain and a hukappa light chain. This compound has a predicted molecular weight (MW) of 146.06 kDa.</p>Couleur et forme :LiquidMasse moléculaire :150 kDaDamnacanthol
<p>Damnacanthol is a useful organic compound for research related to life sciences and the catalog number is T131609.</p>Formule :C16H12O5Couleur et forme :SolidMasse moléculaire :284.267Englumafusp alfa
<p>Englumafusp alfa (CD19-4-1BBL; RO7227166) is a fusion protein combining a CD19-specific antibody domain with trimerized extracellular domains of human 4-1BBL,</p>Couleur et forme :Odour LiquidMifamurtide TFA
<p>Mifamurtide TFA: muramyl dipeptide analog, boosts immunity, activates macrophages/monocytes, potential osteosarcoma research.</p>Formule :C61H110F3N6O21PCouleur et forme :SolidMasse moléculaire :1351.52Vemircopan
CAS :<p>Vemircopan is a complement factor D inhibitor.</p>Formule :C29H28BrN7O3Couleur et forme :SolidMasse moléculaire :602.493Dihydromyristicin
CAS :<p>Dihydromyristicin, a plant flavonoid, curbs inflammation by inhibiting ROS and PI3K/Akt/NF-κB pathways.</p>Formule :C11H14O3Couleur et forme :SolidMasse moléculaire :194.23Ubletamig
CAS :<p>Ubletamig is a humanized IgG4κ monoclonal antibody that targets MUC16.</p>Couleur et forme :LiquidTri(TLR4-IN-C34-PEG2-amide-PEG1)-amide-C3-COOH
<p>Tri(TLR4-IN-C34-PEG2/PEG1)-amide-C3-COOH is a TLR4 inhibiting linker, reducing inflammation in endotoxemia and enterocolitis mouse models.</p>Formule :C78H125N7O42Couleur et forme :SolidMasse moléculaire :1832.85BTH1704
<p>BTH1704 is a human monoclonal antibody targeting MUC1. It facilitates the killing of iC3b-opsonized tumor cells by leukocytes triggered by PGG. BTH1704 is applicable in studies on pancreatic cancer and breast cancer.</p>Couleur et forme :Odour LiquidPterisolic acid B
<p>Pterisolic acid B is a useful organic compound for research related to life sciences and the catalog number is T125924.</p>Formule :C20H26O4Couleur et forme :SolidMasse moléculaire :330.424Pegaldesleukin
CAS :<p>Pegaldesleukin, a PEG-IL2 conjugate, exhibits antiviral properties, potentially slowing HIV progression, preserving immune function.</p>Couleur et forme :LiquidNLRP3-IN-46
<p>NLRP3-IN-46 (Compound 3k) activates the cholinergic anti-inflammatory pathway involved in neuro-immune modulation, thereby inhibiting the activation of the NLRP3 inflammasome. Furthermore, NLRP3-IN-46 suppresses the production of IL-1β in THP-1 cells induced by Uric acid sodium, making it relevant for research in gouty arthritis.</p>Couleur et forme :Odour SolidCD73-IN-16
<p>CD73-IN-16 (compound 18) acts as an inhibitor of hCD73, exhibiting an IC50 value of 0.28 μM.</p>Couleur et forme :Odour SolidTBK1/IKKε-IN-6
CAS :<p>TBK1/IKKε-IN-6 (example 110) is a potent inhibitor of TBK1 and IKKε, with IC50 values of less than 100 nM for both enzymes.</p>Formule :C31H36F2N8O4Couleur et forme :SolidMasse moléculaire :622.678SU1261
<p>SU1261, an IKK inhibitor, exhibits Ki values of 10 nM for IKKα and 680 nM for IKKβ. It effectively inhibits non-canonical NF-κB signaling in U2OS osteosarcoma cells.</p>Couleur et forme :Odour SolidDiprovocim-X
<p>Diprovocim-X, a potent TLR1/2 agonist, has EC50s of 0.14nM (hTLR) and 0.75nM (mTLR), enhances mice's adaptive immunity.</p>Formule :C66H83N7O10Couleur et forme :SolidMasse moléculaire :1134.41P2X7-IN-2 TFA
<p>P2X7-IN-2 TFA inhibits IL-Iβ release (IC50=0.01nM), used in autoimmunity, inflammation & cardiovascular research.</p>Formule :C24H22F7N3O4Couleur et forme :SolidMasse moléculaire :549.44N-Acetyldopamine dimer-2
CAS :<p>Compound 2, an N-acetyldopamine dimer from Periostracum Cicadae, exhibits antioxidant and anti-inflammatory properties.</p>Formule :C20H20N2O6Couleur et forme :SolidMasse moléculaire :384.38COX-2-IN-48
<p>COX-2-IN-48 (5-25) serves as an inhibitor of COX-2, exhibiting an IC50 of 51.7 nM against human COX-2. It displays anti-inflammatory and analgesic effects in various rodent models through inhibition of the NF-κB pathway. COX-2-IN-48 (5-25) inhibits the degradation of IκB, phosphorylation and nuclear translocation of NF-κB p65, and the expression of COX-2 and iNOS.</p>Couleur et forme :Odour SolidSTING agonist-28
CAS :<p>STING agonist-28 (CF510), a non-nucleotide, boosts STING, TBK1, IRF3 phosphorylation, and cytokines; active against SARS-CoV.</p>Formule :C39H46N14O6Couleur et forme :SolidMasse moléculaire :806.87Avatrombopag hydrochloride
CAS :<p>Avatrombopag (AKR-501) - oral, nonpeptide TPO receptor agonist, EC50 3.3 nM, boosts platelet production, CYP2C9 and CYP3A substrate.</p>Couleur et forme :SolidL-156,602
CAS :<p>L-156,602 has a wide range of applications in life science related research.</p>Formule :C38H64N8O13Couleur et forme :SolidMasse moléculaire :840.973Ac-LDEETGEFL-NH2
CAS :<p>Ac-LDEETGEFL-NH2 is a fluorescent molecule designed to target the interaction between the Kelch-like ECH-associated protein 1 (Keap1) and nuclear factor</p>Formule :C48H72N10O19Couleur et forme :SolidMasse moléculaire :1093.14Nurulimab
CAS :<p>Nurulimab (BCD-145) is an anti-CTLA-4 antibody with anti-cancer activity for the study of skin and musculoskeletal diseases.</p>Degré de pureté :95.5% (SDS-PAGE); 97.3% (SEC-HPLC) - 95.5% (SDS-PAGE); 97.3% (SEC-HPLC)Couleur et forme :LiquidExosome Compound Library
<p>76 exosome-related compounds that can be used for high-throughput and high-content screening.</p>Couleur et forme :Odour SolidLYT-200
<p>Lyt-200 is a humanized monoclonal antibody targeting galectin-9 (Galectin-9). It effectively inhibits leukemia cells and can also be studied in combination with methotrexate.</p>Couleur et forme :Odour LiquidAPF
CAS :<p>APF, a low-fluorescence probe, turns bright (490/515 nm) when oxidized by specific radicals; not affected by NO or H2O2.</p>Formule :C26H17NO5Couleur et forme :SolidMasse moléculaire :423.42Eramkafusp Alfa
<p>Eramkafusp alfa is a human IgG1 antibody that targets the murine B lymphocyte antigen CD20, also known as MS4A1 [1].</p>Couleur et forme :Odour LiquidIsuventatug
CAS :<p>Isuventatug is a monoclonal antibody that targets human MICA (MHC I chain-related molecule A) and MICB (MHC I chain-related molecule B). By binding to MICA and MICB, Isuventatug modulates the interaction between immune cells and tumor cells, exhibiting anti-tumor activity. This compound holds potential for research in cancer immunotherapy.</p>Couleur et forme :LiquidMyD88-IN-1
CAS :<p>MyD88-IN-1: Potent MyD88 inhibitor with anti-inflammatory effects, blocking NF-κB and TLR/IL-1 pathways; potential for cancer and inflammation treatment.</p>Formule :C23H24N6O7SDegré de pureté :>99.99%Couleur et forme :SoildMasse moléculaire :528.54BR102910
CAS :<p>BR102910: Selective FAP inhibitor, features 4-thiazolecarboxamide with cyano-difluoro-pyrrolidine and dichlorophenyl elements.</p>Formule :C18H14Cl2F2N4O2SDegré de pureté :97%Couleur et forme :SolidMasse moléculaire :459.3
