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Immunologie et Inflammation

Immunologie et Inflammation

Les inhibiteurs en immunologie et inflammation sont des composés qui modulent la réponse immunitaire et les processus inflammatoires. Ces inhibiteurs sont cruciaux pour étudier les mécanismes de la régulation immunitaire, l'auto-immunité et l'inflammation chronique, ainsi que pour développer des traitements pour les maladies inflammatoires, les allergies et les troubles immunitaires. En ciblant des voies clés du système immunitaire, ces inhibiteurs peuvent aider à réduire les réponses immunitaires excessives ou inappropriées. Chez CymitQuimica, nous offrons une large sélection d'inhibiteurs de haute qualité en immunologie et inflammation pour soutenir vos recherches en immunologie, inflammation et développement thérapeutique.

Sous-catégories appartenant à la catégorie "Immunologie et Inflammation"

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3035 produits trouvés pour "Immunologie et Inflammation"

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  • 4-Methylamino antipyrine hydrochloride

    CAS :
    <p>4-Methylamino antipyrine hydrochloride is an active metabolite of Metamizole.</p>
    Formule :C12H16ClN3O
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :253.73
  • PSMA-D5

    CAS :
    <p>PSMA-D5 exhibits a binding affinity for PSMA with a Ki of 0.21 nM and becomes useful for PSMA tracing following radiolabeling. When marked with [68Ga], PSMA-D5 contains a DOTA chelator, facilitating the convenient labeling with therapeutic radionuclides such as 177Lu and 225Ac. Additionally, [68Ga]-labeled PSMA-D5 demonstrates exceptional pharmacokinetic properties and significant tumor uptake in 22Rv1 tumors. This compound can be employed in the synthesis and research of radiolabeled conjugates (RDC).</p>
    Formule :C57H80N12O24
    Couleur et forme :Solid
    Masse moléculaire :1317.31
  • β-Amyrin acetate

    CAS :
    <p>Beta-Amyrin acetate: HMGCR &amp; sEH inhibitor (IC50 3.4 μM), anti-inflammatory, antifungal, antioxidant, anti-hyperlipidemic.</p>
    Formule :C32H52O2
    Degré de pureté :99.87%
    Couleur et forme :Solid
    Masse moléculaire :468.75
  • Axinelline A

    CAS :
    <p>Axinelline A: COX inhibitor, IC50 of 2.22 μM (COX-2) &amp; 8.89 μM (COX-1), anti-inflammatory.</p>
    Formule :C12H15NO6
    Couleur et forme :Solid
    Masse moléculaire :269.25
  • Biotin-labeled Agatolimod sodium


    <p>Biotin-labeled Agatolimod (sodium), a class B CpG ODN (oligodeoxynucleotide) and TLR9 agonist, facilitates the assessment of cellular uptake and localization of</p>
    Couleur et forme :Odour Solid
  • MC-ND-18


    <p>MC-ND-18 is an ATTEC degrader that facilitates the degradation of NLRP3 via autophagy, exhibiting a DC50 of 125.5 nM in THP-1 cells. It is composed of an NLRP3 ligand, a linker, and an LC3 ligand.</p>
    Formule :C42H42Br2IN3O9S
    Masse moléculaire :1049.00532
  • StemRegenin 1 Hydrochloride

    CAS :
    <p>StemRegenin 1 Hydrochloride is an AhR antagonist (IC₅₀ = 127 nM) that inhibits RANKL-induced osteoclast generation and differentiation.</p>
    Formule :C24H24ClN5OS
    Degré de pureté :99.94%
    Couleur et forme :Solid
    Masse moléculaire :466
  • Schisanchinin D

    CAS :
    <p>Schisanchinin D is a useful organic compound for research related to life sciences. The catalog number is T125682 and the CAS number is 1614245-13-4.</p>
    Formule :C23H30O6
    Couleur et forme :Solid
    Masse moléculaire :402.487
  • (Rac)-γ-Tocopherol

    CAS :
    <p>(Rac)-γ-Tocopherol (DMPBQ) is an isoform of Vitamin E that undergoes conversion to γ-Tocopherol through the action of tocopherol cyclase.</p>
    Formule :C28H48O2
    Couleur et forme :Solid
    Masse moléculaire :416.68
  • Neuroprotective agent 5


    <p>Neuroprotective agent 5 (compound 28) acts as a brain-penetrating agent with anti-neuroinflammatory, antioxidant, and neuroprotective properties. It exhibits potent inhibition of nitric oxide (NO) with an EC50 of 0.49 μM and suppresses the release of pro-inflammatory mediators PGE2 and TNF-α. Additionally, it downregulates the expression of iNOS and COX-2 proteins, facilitating the polarization of BV-2 cells from a pro-inflammatory M1 phenotype to an anti-inflammatory M2 phenotype. Neuroprotective agent 5 also dose-dependently inhibits acetylcholinesterase (AChE) activity and the aggregation of Aβ42. This compound is useful for research into Alzheimer's disease.</p>
    Couleur et forme :Odour Solid
  • Pelgifatamab

    CAS :
    <p>Pelgifatamab (BAY-2315497) is a prostate-specific membrane antigen (PSMA) antibody with potential anticancer activity that can be used to study prostate cancer.</p>
    Degré de pureté :97.9% (SDS-PAGE); 95.1% (SEC-HPLC) - 97.9% (SDS-PAGE); 95.1% (SEC-HPLC)
    Couleur et forme :Liquid
  • M133 peptide


    <p>The M133 peptide is a coronavirus-specific CD4 T cell epitope. In mice infected with the neurotropic coronavirus (strain JHM of mouse hepatitis virus), the M133 peptide demonstrates immunodominance. It activates CD4 T cells by forming an MHC/peptide complex through binding with MHC II molecules, which is recognized by specific TCRs.</p>
    Formule :C84H130N20O25
    Masse moléculaire :1818.9516
  • 2-Iminobiotin

    CAS :
    <p>2-Iminobiotin inhibits iNOS/nNOS; Ki: 21.8 μM (mouse iNOS), 37.5 μM (rat nNOS).</p>
    Formule :C10H17N3O2S
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :243.33
  • Pepinh-MYD

    CAS :
    <p>Pepinh-MYD, a MyD88 inhibitor, incorporates both a domain sequence from MyD88 TIR and a protein transduction sequence to facilitate cell membrane penetration. This compound disrupts MyD88-mediated TLR signaling pathways, effectively inhibiting associated immune responses. Its design is particularly useful for investigating MyD88's function in viral infections.</p>
    Formule :C151H248N50O35S2
    Couleur et forme :Solid
    Masse moléculaire :3388.03
  • SMRT peptide

    CAS :
    <p>SMRT peptide, one of the corepressor factors interacting with the BCL6 BTB domain, binds to the BTB domain of BCL6 to enhance its transcriptional repression function. Additionally, SMRT peptide is utilized for studying protein-protein interactions.</p>
    Formule :C82H142N26O24
    Couleur et forme :Solid
    Masse moléculaire :1876.16
  • Vadastuximab


    <p>Vadastuximab (Anti-Human CD33 Recombinant Antibody) is a humanized anti-CD33 monoclonal antibody for the study of acute myeloid leukemia (AML).</p>
    Degré de pureté :98.5% (SDS-PAGE); 97.3% (SEC-HPLC) - 98.5% (SDS-PAGE); 97.3% (SEC-HPLC)
    Couleur et forme :Liquid
    Masse moléculaire :145.5 kDa
  • PROTAC IRAK4 degrader-11


    <p>PROTACIRAK4 degrader-11 (compound 15) is a PROTAC molecule utilizing a Cereblon ligand, achieving a maximal IRAK4 degradation rate of 96.25% in HEK293 cells, with a DC50 value of 2.29 nM.</p>
    Formule :C41H41F3N8O6
    Masse moléculaire :798.31012
  • NF-κB Signaling Compound Library


    <p>A unique collection of xnum compounds targeting NF-κB signaling for high throughput screening and high content screening;</p>
    Couleur et forme :Odour Solid
  • HSV-60mer sodium


    <p>HSV-60mer sodium is a 60 bp double-stranded oligonucleotide that includes viral DNA motifs from the herpes simplex virus 1 (HSV-1) genome. Transfection of HSV-60mer effectively induces IFN-β in a manner dependent on STING, TBK1, and IFN regulatory factor 3 (IRF3).</p>
  • TLQP-21

    CAS :
    <p>TLQP 21, a VGF-derived peptide, guards CGCs against apoptosis and combats early diet-induced diabetes by boosting energy spend.</p>
    Formule :C107H170N40O26
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :2432.75