Immunologie et Inflammation

Les inhibiteurs en immunologie et inflammation sont des composés qui modulent la réponse immunitaire et les processus inflammatoires. Ces inhibiteurs sont cruciaux pour étudier les mécanismes de la régulation immunitaire, l'auto-immunité et l'inflammation chronique, ainsi que pour développer des traitements pour les maladies inflammatoires, les allergies et les troubles immunitaires. En ciblant des voies clés du système immunitaire, ces inhibiteurs peuvent aider à réduire les réponses immunitaires excessives ou inappropriées. Chez CymitQuimica, nous offrons une large sélection d'inhibiteurs de haute qualité en immunologie et inflammation pour soutenir vos recherches en immunologie, inflammation et développement thérapeutique.

Sous-catégories appartenant à la catégorie "Immunologie et Inflammation"

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3035 produits trouvés pour "Immunologie et Inflammation"

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DDO-7263
CAS :
- 2254004-96-9
DDO-7263, a 1,2,4-Oxadiazole, boosts Nrf2 by binding Rpn6, blocking 26S proteasome assembly, and has anti-inflammatory effects.
Formule :C₁₄H₉F₂N₃O
Degré de pureté :99.85%
Couleur et forme :Solid
Masse moléculaire :273.24
Ref: TM-T60487
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Keap1-Nrf2-IN-16
CAS :
- 1362661-40-2
Keap1-Nrf2-IN-16 is a biologically active peptide with KEAP1 binding activity.
Formule :C₇₃H₁₁₄N₁₆O₂₆
Couleur et forme :Solid
Masse moléculaire :1631.78
Ref: TM-T80260
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AMPCP
CAS :
- 104835-70-3
AMPCP is an Ecto-5'-nucleotidase (CD73) inhibitor.
Formule :C₁₁H₁₅N₅Na₂O₉P₂
Couleur et forme :Solid
Masse moléculaire :469.19
Ref: TM-T71538
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4-CPPC
CAS :
- 29553-70-6
4-CPPC inhibits MIF-2 (IC50=27μM), not MIF-1; blocks MIF-2/CD74 binding and MIF-2-induced ERK1/2 in fibroblasts.
Formule :C₁₄H₉NO₆
Degré de pureté :97.50% - 98.03%
Couleur et forme :Solid
Masse moléculaire :287.22
Ref: TM-T38293
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Fenquinotrione
CAS :
- 1342891-70-6
Fenquinotrione, a 4-hydroxyphenylpyruvate dioxygenase (HPPD) inhibitor, exhibits IC50 values of 27.2 and 44.7 nM against HPPD from rice and Arabidopsis thaliana
Formule :C₂₂H₁₇ClN₂O₅
Couleur et forme :Solid
Masse moléculaire :424.83
Ref: TM-T82410
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TLR8 agonist 5
CAS :
- 2413016-41-6
TLR8 Agonist 5, exhibiting potent efficacy as a TLR8 agonist, demonstrates an EC50 of 20 nM in HEK-Blue hTLR8, effectively activating the immune response.
Formule :C₃₁H₄₀N₆O₅
Couleur et forme :Solid
Masse moléculaire :576.69
Ref: TM-T72830
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PK68
CAS :
- 2173556-69-7
PK68 selectively inhibits RIPK1 (IC50=90nM), potentially useful in inflammation and cancer metastasis studies.
Formule :C₂₂H₂₄N₄O₃S
Degré de pureté :98.09% - 99.64%
Couleur et forme :Solid
Masse moléculaire :424.52
Ref: TM-T12493
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ML-090
CAS :
- 531-46-4
ML-090 is NOX1-specific inhibitor(IC50 = 90 nM) which is >100 selectivity for NOX1 over NOX2, NOX3, NOX4 (all IC50s >10 μM).
Formule :C₁₄H₁₀N₄
Degré de pureté :98.55%
Couleur et forme :Solid
Masse moléculaire :234.26
Ref: TM-T22990
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Glabrescone C
CAS :
- 2757214-13-2
Glabrescone C exhibits strong anti-inflammatory properties through direct binding to IKKα/β.
Formule :C₁₉H₂₂O₇
Couleur et forme :Solid
Masse moléculaire :362.37
Ref: TM-T72899
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TLR7/8 agonist 8
CAS :
- 2649170-16-9
TLR7/8 agonist 8 (compound 24m) is a potent dual agonist for toll-like receptors 7 and 8 (TLR7/8), exhibiting half-maximal effective concentrations (EC50s) of
Formule :C₂₄H₃₀N₆O
Couleur et forme :Solid
Masse moléculaire :418.53
Ref: TM-T79068
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PF 184
CAS :
- 1187460-81-6
IKKβ inhibitor
Formule :C₃₂H₃₂ClFN₆O₄
Degré de pureté :98%
Couleur et forme :Solid
Masse moléculaire :619.09
Ref: TM-T23137
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NLRP3-IN-9
CAS :
- 88039-46-7
NLRP3-IN-9 (INF-4E) irreversibly inhibits NLRP3 ATPase, caspase-1, and prevents pyroptosis in THP-1 cells.
Formule :C₁₂H₁₃ClO₃
Degré de pureté :99.64%
Couleur et forme :Solid
Masse moléculaire :240.68
Ref: TM-T28178
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IKK-IN-4
CAS :
- 615529-94-7
IKK-IN-4 is a potent and selective inhibitor of IkappaB kinase 2 with IC 50 values of 45 and 650 nM against IKKβ and IKKα, respectively [1].
Formule :C₁₈H₁₉N₅S
Couleur et forme :Solid
Masse moléculaire :337.44
Ref: TM-T61059
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DNA polymerase-IN-1
CAS :
- 809234-33-1
DNA polymerase-IN-1 exhibits antiproliferative activity against tumor cells and inhibits Taq DNA polymerase as a DNA polymerase inhibitor.
Formule :C₁₀H₇ClO₄
Degré de pureté :99.16%
Couleur et forme :Solid
Masse moléculaire :226.61
Ref: TM-T80644
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TLR7 agonist 23
CAS :
- 2408268-38-0
TLR7 agonist23 (compound 12b) is a potent agonist of Toll-like receptor-7 (TLR7), with an EC50 value of 0.15 uM. It is suitable for research in immune diseases.
Formule :C₂₁H₂₂N₄O₂
Couleur et forme :Solid
Masse moléculaire :362.42
Ref: TM-T88779
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Arginase inhibitor 1
CAS :
- 1345808-25-4
Arginase inhibitor 1 is a potent inhibitor of human arginases I and II (IC50s: 223 and 509 nM).
Formule :C₁₃H₂₇BN₂O₄
Couleur et forme :Solid
Masse moléculaire :286.18
Ref: TM-T10367
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(R)-IL-17 modulator 4
CAS :
- 2446804-29-9
(R)-IL-17 modulator 4, an R-isomer prodrug of IL-17 modulator 1, is potent and taken orally.
Formule :C₂₇H₃₄N₆O₂
Couleur et forme :Solid
Masse moléculaire :474.6
Ref: TM-T63089
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Factor B-IN-2
CAS :
- 2760669-72-3
Factor B-IN-2 is a potent inhibitor (IC50: 1.5 μM) of complement factor B. Factor B-IN-2 can be used to study inflammatory and immune-related diseases.
Formule :C₂₅H₃₂N₂O₄
Couleur et forme :Solid
Masse moléculaire :424.53
Ref: TM-T62292
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STING-IN-5
CAS :
- 2920064-17-9
STING-IN-5 suppresses NO synthesis in macrophages, inhibits STING pathway with IC50 of 1.15 μM, and may aid anti-inflammatory and sepsis research.
Formule :C₄₇H₆₇NO₉S₂
Degré de pureté :98%
Couleur et forme :Solid
Masse moléculaire :854.17
Ref: TM-T75011
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Anti-inflammatory agent 46
CAS :
- 2925586-96-3
Anti-inflammatory agent 46 (compound 7h), exhibiting nitric oxide (NO) inhibitory properties, demonstrates a high affinity for iNOS through low binding energies
Formule :C₂₄H₁₉FN₂O₃S
Degré de pureté :98%
Couleur et forme :Solid
Masse moléculaire :434.48
Ref: TM-T79473
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RIP1 kinase inhibitor 4
CAS :
- 2919836-00-1
RIP1 Kinase Inhibitor 4 (Compound 3) is an effective inhibitor of RIP1K, exhibiting an EC50 of ≤ 1000 nM [1].
Formule :C₂₃H₂₃N₅
Degré de pureté :98%
Couleur et forme :Solid
Masse moléculaire :369.46
Ref: TM-T79041
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TLR4 agonist-1
CAS :
- 2374139-51-0
TLR4 agonist-1 (compound 17a) serves as a potent activator of Toll-like Receptor 4 (TLR4) and stimulates the production of MIP-1β in RAW 264.7 and MM6 cells [1
Formule :C₈₁H₁₅₈N₃O₁₅P
Couleur et forme :Solid
Masse moléculaire :1445.11
Ref: TM-T80978
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hnNOS-IN-2
CAS :
- 2700326-00-5
Compound 17, also known as hnNOS-IN-2, is an inhibitor of human neuronal nitric oxide synthase (hnNOS) that exhibits good metabolic stability.
Formule :C₁₈H₂₃F₂N₃
Degré de pureté :98%
Couleur et forme :Solid
Masse moléculaire :319.39
Ref: TM-T78738
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Aminoguanidine hemisulfate
CAS :
- 996-19-0
Aminoguanidine hemisulfate, an inhibitor of nitric oxide synthases (NOS) and reactive oxygen species (ROS), effectively suppresses ANE-induced ROS production in
Formule :CH₆N₄H₂SO₄
Degré de pureté :98%
Couleur et forme :Solid
Masse moléculaire :123.115
Ref: TM-T78229
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IMD-biphenylC
CAS :
- 2928463-42-5
IMD-biphenylC: New, dual-action imidazoquinolinone dimer; inhibits tumor growth, low inflammation/toxicity.
Formule :C₃₅H₃₃N₅O₃
Degré de pureté :98%
Couleur et forme :Solid
Masse moléculaire :571.67
Ref: TM-T72871
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ICy-Q
CAS :
- 2863682-83-9
ICy-Q, a NIR reagent activated by NQO-1, triggers pyroptosis in pancreatic cancer cells, aiding diagnosis.
Formule :C₄₈H₅₀I₂N₂O₅
Degré de pureté :98%
Couleur et forme :Solid
Masse moléculaire :988.73
Ref: TM-T74923
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GBT1118
CAS :
- 1628799-51-8
GBT1118 is an orally active allosteric modulator of haemoglobin oxygen affinity, enhancing tolerance to acute severe hypoxia and suitable for hypoxia research.
Formule :C₁₉H₂₀N₂O₄
Degré de pureté :99.69%
Couleur et forme :Solid
Masse moléculaire :340.37
Ref: TM-T78075
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TBK1-IN-1
CAS :
- 3031785-78-8
TBK1-IN-1 is a TANK-binding kinase 1 inhibitor with anticancer activity.TBK1-IN-1 inhibits the expression of TBK1 downstream target genes, cxcl10 and ifnβ.
Formule :C₂₇H₃₇N₇O₂
Degré de pureté :>99.99%
Couleur et forme :Solid
Masse moléculaire :491.63
Ref: TM-T73322
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Dapsone hydroxylamine
CAS :
- 32695-27-5
Dapsone hydroxylamine (DDS-NOH) promotes methemoglobinemia, impedes catalase (CAT) activity, and suppresses the generation of reactive oxygen species, while
Formule :C₁₂H₁₂N₂O₃S
Degré de pureté :98%
Couleur et forme :Solid
Masse moléculaire :264.3
Ref: TM-T78517
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NLRP3-IN-21
CAS :
- 2956791-61-8
NLRP3-IN-21 (compound L38) is an inhibitor of the NLRP3 inflammasome that possesses anti-inflammatory properties.
Formule :C₂₀H₁₃Cl₂F₃N₆O₂S
Degré de pureté :98%
Couleur et forme :Solid
Masse moléculaire :529.32
Ref: TM-T78894
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MALT1-IN-7
CAS :
- 2178993-11-6
MALT1-IN-7 (compound 142b) is a potent inhibitor of MALT1 protease with potential for cancer research.
Formule :C₁₉H₁₇F₃N₈O₂S
Couleur et forme :Solid
Masse moléculaire :478.45
Ref: TM-T63134
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IMD-vanillin
CAS :
- 2928463-38-9
IMD-vanillin is a novel compound characterized as an imidazoquinolinone-derived dimer with NF-κB immunomodulatory properties.
Formule :C₃₇H₄₅N₇O₄
Degré de pureté :98%
Couleur et forme :Solid
Masse moléculaire :651.8
Ref: TM-T72926
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IRAK4-IN-28
CAS :
- 2952532-92-0
IRAK4-IN-28 (compound 42), an orally-active IRAK4 inhibitor (IC50=8.9 nM), exhibits strong binding affinity with a Kd of 0.58 nM for the target enzyme.
Formule :C₂₇H₃₁N₉O₃
Degré de pureté :98%
Couleur et forme :Solid
Masse moléculaire :529.59
Ref: TM-T79337
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CCT374705
CAS :
- 2640647-90-9
CCT374705, an orally active BCL6 inhibitor, exhibits potent antiproliferative effects in vitro and effectively inhibits tumor growth in a lymphoma xenograft
Formule :C₂₁H₁₈ClF₃N₄O₂
Couleur et forme :Solid
Masse moléculaire :450.84
Ref: TM-T78177
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Galectin-3 antagonist 2
CAS :
- 2921603-02-1
Galectin-3: a lectin aiding BCP-ALL cell migration & drug resistance.
Formule :C₂₂H₂₃NO₁₀
Degré de pureté :98%
Couleur et forme :Solid
Masse moléculaire :461.42
Ref: TM-T74538
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BF738735
CAS :
- 1436383-95-7
BF738735 is a selective inhibitor of phosphatidylinositol 4-kinase III beta (PI4KIIIβ, IC50 = 5.7 nM) showing higher activity over α(IC50 = 1.7 μM).
Formule :C₂₁H₁₉FN₄O₃S
Degré de pureté :90%
Couleur et forme :Solid
Masse moléculaire :426.46
Ref: TM-T16530
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RIPK2-IN-3
CAS :
- 1290490-78-6
RIPK2-IN-3 (FCG806791773) is a RIPK2 inhibitor with anti-inflammatory and anticancer activities, useful for research on immune diseases and cancer.
Formule :C₂₅H₂₂N₄O₂
Degré de pureté :99.57%
Couleur et forme :Solid
Masse moléculaire :410.47
Ref: TM-T78597
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h-NTPDase-IN-3
CAS :
- 2939933-10-3
h-NTPDase-IN-3 is an h-NTPDase inhibitor that inhibits h-NTPDase1, h-NTPDase2, h-NTPDase3 and h-NTPDase8.
Formule :C₁₆H₁₀N₄S
Degré de pureté :98.24%
Couleur et forme :Solid
Masse moléculaire :290.34
Ref: TM-T79622
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NVS-MALT1
CAS :
- 2772439-62-8
NVS-MALT1 is an allosteric inhibitor of MALT1 [1].
Formule :C₂₄H₂₇ClF₃N₅O₄S
Couleur et forme :Solid
Masse moléculaire :574.02
Ref: TM-T73266
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(-)-Bornyl ferulate
CAS :
- 55511-07-4
(-)-Bornyl ferulate is a dual inhibitor of 5-lipoxygenase and cyclooxygenase (COX), exhibiting half-maximal inhibitory concentrations (IC50s) of 10.4 μM for 5-
Formule :C₂₀H₂₆O₄
Degré de pureté :98%
Couleur et forme :Solid
Masse moléculaire :330.42
Ref: TM-T80651
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Antitumor agent-114
CAS :
- 2757762-91-5
Antitumor Agent-114, a potent STING (stimulator of interferon genes) agonist, activates immune responses and diminishes tumor size in mouse breast cancer models
Formule :C₃₉H₅₀F₂N₁₀O₁₃P₂
Degré de pureté :98%
Couleur et forme :Solid
Masse moléculaire :966.82
Ref: TM-T79320
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NF-κB-IN-13
CAS :
- 117596-92-6
NF-κB-IN-13 (compound 12) markedly suppresses LPS-induced NF-κB activation and NO synthesis in RAW264.7 macrophages, exhibiting anti-inflammatory properties [1
Formule :C₂₀H₂₀O₅
Degré de pureté :98%
Couleur et forme :Solid
Masse moléculaire :340.37
Ref: TM-T79999
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BI 7446
CAS :
- 2767011-00-5
BI 7446 is a potent and selective cyclic dinucleotide (CDN)-based stimulator of interferon genes (STING) agonist capable of activating all five STING variants
Formule :C₂₀H₂₂FN₉O₁₀P₂S₂
Degré de pureté :98%
Couleur et forme :Solid
Masse moléculaire :693.52
Ref: TM-T79313
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CD73-IN-6
CAS :
- 2757808-96-9
CD73-IN-6, serves as a potent inhibitor of CD73. This compound finds utility in cancer research [1].
Formule :C₂₀H₁₅N₇O₂
Couleur et forme :Solid
Masse moléculaire :385.38
Ref: TM-T61691
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FCE-27164
CAS :
- 154755-58-5
FCE-27164 inhibits PDGF-β and IL-7 receptor binding, potentially modulating inflammatory and immune responses for therapeutic applications.
Formule :C₄₅H₃₄N₁₀Na₆O₂₃S₆
Degré de pureté :96.04%
Couleur et forme :Solid
Masse moléculaire :1413.11
Ref: TM-T70463
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Dexamethasone palmitate
CAS :
- 14899-36-6
DXP, a lipophilic prodrug of Dexamethasone, has 47x less glucocorticoid receptor affinity; it's an agonist & anti-inflammatory.
Formule :C₃₈H₅₉FO₆
Degré de pureté :99.28%
Couleur et forme :Solid
Masse moléculaire :630.87
Ref: TM-T15102
+ Info
CD73-IN-10
CAS :
- 2766565-91-5
CD73-IN-10, a potent inhibitor of CD73, aids in creating cancer drugs by hindering adenosine synthesis, which fosters tumor growth.
Formule :C₁₅H₁₃F₂N₅O₂
Couleur et forme :Solid
Masse moléculaire :333.29
Ref: TM-T61000
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TLR7 agonist 14
CAS :
- 2832199-45-6
Compound 17b, a TLR7 agonist also known as TLR7 agonist 14, exhibits high potency with an EC50 of 18 nM.
Formule :C₂₉H₃₆N₆O₃
Couleur et forme :Solid
Masse moléculaire :516.63
Ref: TM-T79749
+ Info
BD-AcAc 2
CAS :
- 1208313-97-6
BD-AcAc 2 (Ketone Ester) is a ketone monoester and can be used as a source of oral nutritional ketones.
Formule :C₈H₁₆O₄
Degré de pureté :99.62%
Couleur et forme :Solid
Masse moléculaire :176.21
Ref: TM-T10492
+ Info
NLRP3-IN-18
CAS :
- 2769040-06-2
NLRP3-IN-18, also known as compound 13, is a potent inhibitor of NLRP3, demonstrating an IC50 value of ≤1.0 µM [1].
Formule :C₁₉H₁₈ClN₃O
Degré de pureté :98%
Couleur et forme :Solid
Masse moléculaire :339.82
Ref: TM-T78180
+ Info
Friluglanstat
CAS :
- 1422203-86-8
Friluglanstat is an inhibitor of the enzyme prostaglandin E synthase (mPGES-1) and exhibits anti-inflammatory activity [1].
Formule :C₂₅H₂₀ClF₃N₄O₃
Degré de pureté :98%
Couleur et forme :Solid
Masse moléculaire :516.9
Ref: TM-T79846
+ Info
CD38 inhibitor 2
CAS :
- 2597933-78-1
CD38 inhibitor 2 is a potent CD38 inhibitor ( IC 50 = 0.01 ~ 0.1 μΜ).
Formule :C₁₉H₂₄N₆O₃
Couleur et forme :Solid
Masse moléculaire :384.43
Ref: TM-T61681
+ Info
MAPK-IN-1
CAS :
- 2470587-69-8
MAPK-IN-1 inhibits MAPK for Alzheimer's research with anti-inflammatory effects, IC50 of 23.84 μM against AChE.
Formule :C₁₉H₁₈O₄
Couleur et forme :Solid
Masse moléculaire :310.34
Ref: TM-T60754
+ Info
NLRP3-IN-22
CAS :
- 1193329-98-4
NLRP3-IN-22 (Compound II-4) is an inhibitor of NLRP3, exhibiting a 67% inhibition rate at a concentration of 10 μM [1].
Formule :C₁₉H₁₂F₃NO₄S
Degré de pureté :98%
Couleur et forme :Solid
Masse moléculaire :407.36
Ref: TM-T81666
+ Info
W-54011
CAS :
- 405098-33-1
W-54011: potent non-peptide C5a receptor blocker; binds 125I-C5a (Ki=2.2nM); stops Ca2+ movement, chemotaxis, ROS in neutrophils (IC50=1.6-3.1nM).
Formule :C₃₀H₃₇ClN₂O₂
Degré de pureté :96.8%
Couleur et forme :Solid
Masse moléculaire :493.08
Ref: TM-T17250
+ Info
OATD-02
CAS :
- 2146132-73-0
OATD-02 is an orally active, competitive, reversible, noncovalent inhibitor with slow offset kinetics that targets both Arginase1 and 2, exhibiting inhibitory
Formule :C₁₂H₂₅BN₂O₄
Degré de pureté :98%
Couleur et forme :Solid
Masse moléculaire :272.15
Ref: TM-T79319
+ Info
Keap1-Nrf2-IN-15
CAS :
- 2456295-45-5
Keap1-Nrf2-IN-15 (Compound 24a) is a potent inhibitor of the Keap1-Nrf2 protein-protein interaction, displaying IC50 values of 77 nM in a fluorescence
Formule :C₃₉H₃₅N₃O₁₂S₂
Couleur et forme :Solid
Masse moléculaire :801.84
Ref: TM-T78697
+ Info
5J-4
CAS :
- 827001-82-1
5J-4 is a potent a blocker of calcium release-activated calcium (CRAC) channel and store-operated calcium entry (SOCE).
Formule :C₁₆H₁₂N₂O₃S
Degré de pureté :96.12%
Couleur et forme :Solid
Masse moléculaire :312.34
Ref: TM-T24984
+ Info
JT002
CAS :
- 2238820-43-2
JT002 is an orally active NLRP3 inflammasome inhibitor that decreases the production of NLRP3-dependent proinflammatory cytokines (such as IL-1β, IL-1α, IL-18)
Formule :C₂₀H₂₄N₄O₅S
Degré de pureté :98%
Couleur et forme :Solid
Masse moléculaire :432.49
Ref: TM-T78822
+ Info
Nitric oxide production-IN-1
CAS :
- 1013405-26-9
Nitric oxide production-IN-1 (Compound 1) is an inhibitor of nitric oxide (NO) production extracted from Tupistra chinensis.
Formule :C₃₃H₅₂O₁₅
Degré de pureté :98%
Couleur et forme :Solid
Masse moléculaire :688.76
Ref: TM-T79981
+ Info
TMV-IN-2
CAS :
- 2883408-32-8
TMV-IN-2, a chalcone, inhibits TMV with an EC50 of 89.9 μg/mL, used in infection and tumor studies.
Formule :C₂₇H₂₃FO₄
Couleur et forme :Solid
Masse moléculaire :430.47
Ref: TM-T74712
+ Info
3'-Azido-3'-deoxy-5-methylcytidine
CAS :
- 1282040-14-5
3'-Azido-3'-deoxy-5-methylcytidine inhibits HIV-1 reverse transcriptase(EC50 = 0.06 μM) and is an effective inhibitor of xenotropic murine leukemia-related
Formule :C₁₀H₁₄N₆O₄
Degré de pureté :99.55%
Couleur et forme :Solid
Masse moléculaire :282.26
Ref: TM-T10133
+ Info
Ro26-4550
CAS :
- 193744-04-6
Ro26-4550 is a competitive reversible inhibitor of interleukin-2 (IL-2) binding to IL-2R α-subunit (IC50 = 3 μM).
Formule :C₂₆H₃₀N₄O₃
Degré de pureté :98%
Couleur et forme :Solid
Masse moléculaire :446.54
Ref: TM-T28599
+ Info
Keap1-Nrf2-IN-6
Keap1-Nrf2-IN-6 is a potent, selective inhibitor of the Keap1-Nrf2 protein−protein interaction (PPI), demonstrating an inhibitory concentration (IC50) of 41 nM
Formule :C₃₀H₃₄N₄O₈S
Couleur et forme :Solid
Masse moléculaire :610.68
Ref: TM-T72760
+ Info
PF-184
PF-184: potent IKK-2 inhibitor, selective over 30+ kinases; useful for asthma & COPD research. IC50: 37 nM.
Formule :C₃₂H₃₂ClFN₆O₄
Couleur et forme :Solid
Masse moléculaire :619.09
Ref: TM-T73470
+ Info
RPR-106541
CAS :
- 159001-35-1
RPR-106541, a GR agonist, is used potentially for the treatment of asthma.
Formule :C₂₄H₃₄F₂O₄S
Couleur et forme :Solid
Masse moléculaire :456.59
Ref: TM-T28616
+ Info
IFN α-IFNAR-IN-1 hydrochloride
CAS :
- 2070014-98-9
IFN alpha-IFNAR-IN-1 HCl blocks IFN-α/IFNAR binding; IC50 2-8 μM in BM-pDCs' MVA-induced IFN-α response.
Formule :C₁₈H₁₈ClNS
Degré de pureté :99.77%
Couleur et forme :Solid
Masse moléculaire :315.86
Ref: TM-T11630
+ Info
TMV-IN-4
CAS :
- 1820823-40-2
TMV-IN-4, a TMV inhibitor, enhances plant defense and TMV resilience by interacting with helicase, increasing peroxidase and SOD activity.
Formule :C₁₈H₂₁NO₄
Couleur et forme :Solid
Masse moléculaire :315.36
Ref: TM-T75028
+ Info
CD73-IN-4
CAS :
- 2216764-29-1
CD73-IN-4 is a potent and selective methylenephosphonic acid CD73 inhibitor
Formule :C₁₆H₂₃ClN₅O₇P
Degré de pureté :98.61%
Couleur et forme :Solid
Masse moléculaire :463.81
Ref: TM-T9210
+ Info
(R)-MALT1-IN-7
CAS :
- 2178993-10-5
(R)-MALT1-IN-7 (compound 142a) is a potent inhibitor of MALT1 protease and has potential for cancer research.
Formule :C₁₉H₁₇F₃N₈O₂S
Couleur et forme :Solid
Masse moléculaire :478.45
Ref: TM-T63133
+ Info
Bay 65-1942 (R form)
CAS :
- 758683-21-5
Bay 65-1942 R form is the less active R-form of Bay 65-1942. Bay 65-1942 is a selective and ATP-competitive IKKβ inhibitor.
Formule :C₂₂H₂₅N₃O₄
Degré de pureté :98%
Couleur et forme :Solid
Masse moléculaire :395.45
Ref: TM-T10472
+ Info
BW 755C
CAS :
- 66000-40-6
BW 755C is a dual inhibitor of 5-lipoxygenase (5-LO) and cyclooxygenase (COX) pathways.
Formule :C₁₀H₁₀F₃N₃
Degré de pureté :96.52%
Couleur et forme :Solid
Masse moléculaire :229.2
Ref: TM-T22054
+ Info
ST 2825
CAS :
- 894787-30-5
ST 2825 is a specific MyD88 dimerization inhibitor. ST2825 inhibition of IL-1β-mediated activation of NF-κB transcriptional activity.
Formule :C₂₇H₂₈Cl₂N₄O₅S
Degré de pureté :98%
Couleur et forme :Solid
Masse moléculaire :591.51
Ref: TM-T16937
+ Info
CD73-IN-11
CAS :
- 2766566-11-2
CD73-IN-11 is a potent inhibitor used to prepare medication for cancer by blocking adenosine production, which fosters tumor growth.
Formule :C₁₄H₁₀F₃N₅O₂
Couleur et forme :Solid
Masse moléculaire :337.26
Ref: TM-T61053
+ Info
STING Agonist D61
CAS :
- 2850251-27-1
STING agonist D61 is a compound that activates the stimulator of interferon genes (STING), leading to the induction of IFN3-inducible secreted alkaline
Formule :C₂₉H₂₉F₃N₈O₄
Couleur et forme :Solid
Masse moléculaire :610.60
Ref: TM-T83841
+ Info
GSK2256294A
CAS :
- 1142090-23-0
GSK2256294A (GSK 2256294) is potent, selective inhibitor of recombinant human, rat and mouse sEH with IC50 of 27 pM, 61 pM and 189 pM, respectively.
Formule :C₂₁H₂₄F₃N₇O
Degré de pureté :99.86% - 99.86%
Couleur et forme :Solid
Masse moléculaire :447.46
Ref: TM-T15430
+ Info
Glu-urea-Glu-NHS ester
CAS :
- 1228927-36-3
Compound 21, Glu-urea-Glu-NHS ester, an activated N-hydroxysuccinamide (NHS) ester derivative of Glu-urea-Glu, serves as a pharmacophore for conjugation to prostate specific membrane antigen (PSMA) inhibitors [1].
Formule :C₂₇H₄₃N₃O₁₁
Couleur et forme :Solid
Masse moléculaire :585.64
Ref: TM-T84761
+ Info
Trovafloxacin mesylate
CAS :
- 147059-75-4
Trovafloxacin: broad-spectrum fluoroquinolone, blocks DNA gyrase/topoisomerase IV and PANX1 channel (IC50=4μM).
Formule :C₂₁H₁₉F₃N₄O₆S
Degré de pureté :99.18%
Couleur et forme :Solid
Masse moléculaire :512.46
Ref: TM-T13231L
+ Info
Argininosuccinic acid disodium
CAS :
- 918149-29-8
Argininosuccinic acid disodium, involved in the urea cycle's fourth step, is cleaved by argininosuccinate lyase (ASL) into arginine and fumarate.
Formule :C₁₀H₁₆N₄Na₂O₆
Degré de pureté :98%
Couleur et forme :Solid
Masse moléculaire :334.24
Ref: TM-T82972
+ Info
Dimethoxycurcumin
CAS :
- 160096-59-3
Dimethoxycurcumin is a stable curcumin analog causing epigenetic shifts in leukemia cells, affecting gene expression.
Formule :C₂₃H₂₄O₆
Degré de pureté :99.87%
Couleur et forme :Solid
Masse moléculaire :396.43
Ref: TM-T19853
+ Info
MALT1-IN-9
CAS :
- 2577170-77-3
MALT1-IN-9: potent MALT1 protease inhibitor, IC50 <500 nM in Raji cells, significant anticancer effects.
Formule :C₁₆H₁₂ClF₃N₆O
Couleur et forme :Solid
Masse moléculaire :396.75
Ref: TM-T61867
+ Info
Nrf2-IN-1
CAS :
- 1610022-76-8
Nrf2-IN-1 is an nuclear factor-erythroid 2-related factor 2 (Nrf2) inhibitor. Nrf2-IN-1 is developed for the research of acute myeloid leukemia (AML).
Formule :C₂₁H₂₂ClN₃O₂
Degré de pureté :95.00% - 99.68%
Couleur et forme :Solid
Masse moléculaire :383.87
Ref: TM-T12253
+ Info
Glutathione ethyl ester
CAS :
- 92614-59-0
Glutathione ethyl ester is a cell-permeable, modified form of glutathione (GSH) that undergoes rapid hydrolysis by esterases in vivo to restore GSH levels.
Formule :C₁₂H₂₁N₃O₆S
Degré de pureté :98.958%
Couleur et forme :Soild
Masse moléculaire :335.38
Ref: TM-T78616
+ Info
Nrf2 activator-7
CAS :
- 2456295-39-7
Nrf2 Activator-7 (Compound 12b) effectively enhances the Nrf2 signaling pathway as a potent Nrf2 activator.
Formule :C₃₅H₃₂N₂O₁₁S₂
Couleur et forme :Solid
Masse moléculaire :720.77
Ref: TM-T78696
+ Info
STING agonist-3
CAS :
- 2138299-29-1
STING agonist-3: non-nucleotide, selective, anti-tumor with pEC50=7.5, pIC50=9.5, could enhance cancer therapy.
Formule :C₃₇H₄₂N₁₂O₆
Degré de pureté :98%
Couleur et forme :Solid
Masse moléculaire :750.81
Ref: TM-T13014
+ Info
COX-2-IN-30
CAS :
- 1160498-08-7
COX-2-IN-30, a benzenesulfonamide derivative, is an orally active, dual inhibitor of cyclooxygenase-2 (COX-2; IC50 = 49 nM) and cyclooxygenase-1 (COX-1; IC50 =
Formule :C₁₇H₁₆N₆O₃S
Degré de pureté :98%
Couleur et forme :Solid
Masse moléculaire :384.41
Ref: TM-T78705
+ Info
Thromboxane B3
CAS :
- 71953-80-5
Thromboxane B3 (TXB3), the stable hydrolysis product of TXA3, is synthesized from eicosapentaenoic acid (EPA) through the action of COX and thromboxane synthase enzymes. This compound is biosynthesized in several tissues, including seminal vesicles, lungs, polymorphonuclear leukocytes (PMNL), and ocular tissues.
Formule :C₂₀H₃₂O₆
Couleur et forme :Solid
Masse moléculaire :368.5
Ref: TM-T84569
+ Info
TIM-3-IN-2
CAS :
- 1113126-49-0
TIM-3-IN-2 is a Tim3 inhibitor that inhibits the action of TIM-3.TIM-3-IN-2 reverses TIM-3-mediated pro-inflammatory cytokine effects.
Formule :C₂₅H₂₃N₃O₆
Degré de pureté :98.93%
Couleur et forme :Solid
Masse moléculaire :461.47
Ref: TM-T79365
+ Info
TLR8 agonist 6
CAS :
- 2616605-55-9
Compound A, a potent TLR8 agonist, exhibits an EC50 of 0.052 µM and promotes the production of IL-12p40 in human PBMCs with an EC50 of 0.031 µM.
Formule :C₁₉H₂₉N₇O₂
Couleur et forme :Solid
Masse moléculaire :387.48
Ref: TM-T79151
+ Info
Lobenzarit sodium
CAS :
- 64808-48-6
Lobenzarit sodium (CCA) is an agent with the activity of antirheumatic and antioxidative.
Formule :C₁₄H₈ClNNa₂O₄
Degré de pureté :99.35%
Couleur et forme :Solid
Masse moléculaire :335.65
Ref: TM-T20800
+ Info
IRAK inhibitor 3
CAS :
- 1012343-93-9
IRAK inhibitor 3 is an interleukin-1 (IL-1) receptor-associated kinase (IRAK) modulator.
Formule :C₂₁H₂₁N₅O₄S
Degré de pureté :98.86%
Couleur et forme :Solid
Masse moléculaire :439.49
Ref: TM-T11670
+ Info
CGA-JK3
CAS :
- 1621626-06-9
CGA-JK3 is an IkappaB kinase inhibitor in innate immune process.
Formule :C₁₅H₁₉NO₃
Degré de pureté :98%
Couleur et forme :Solid
Masse moléculaire :261.32
Ref: TM-T26989
+ Info
3M-011
CAS :
- 642473-62-9
3M-011: potent TLR7/8 agonist, cytokine inducer, enhances radiotherapy, fights H3N2, and has anti-tumor effects.
Formule :C₁₈H₂₅N₅O₃S
Degré de pureté :98%
Couleur et forme :Solid
Masse moléculaire :391.49
Ref: TM-T14035
+ Info
Benoxaprofen
CAS :
- 51234-28-7
Benoxaprofen (NSC-299582) is a non-steroidal anti-inflammatory drug.
Formule :C₁₆H₁₂ClNO₃
Degré de pureté :98.87%
Couleur et forme :Solid
Masse moléculaire :301.72
Ref: TM-T19679
+ Info
Stobadine
CAS :
- 85202-17-1
Stobadine, a potent antioxidant, safeguards endoplasmic reticulum (ER) membrane fluidity against free radical-induced changes.
Formule :C₁₃H₁₈N₂
Degré de pureté :98%
Couleur et forme :Solid
Masse moléculaire :202.3
Ref: TM-T78067
+ Info
NLRP3-IN-17
CAS :
- 2254432-75-0
NLRP3-IN-17 is a potent, selective, and orally active inhibitor of the NLRP3 inflammasome, demonstrating an IC50 of 7 nM.
Formule :C₂₁H₂₂N₄O₂S
Degré de pureté :98%
Couleur et forme :Solid
Masse moléculaire :394.49
Ref: TM-T78168
+ Info
HBF-0259
CAS :
- 957011-15-3
HBF-0259 is an inhibitors of hepatitis B virus surface antigen (HBsAg) secretion with an EC50 of 11.3 μM and a CC50 value of >50 μM in HepG2.2.15 cells.
Formule :C₁₆H₁₂Cl₂FN₅
Degré de pureté :98.07% - 99.42%
Couleur et forme :Solid
Masse moléculaire :364.2
Ref: TM-T27527
+ Info
TLR7 agonist 4
CAS :
- 2413016-42-7
TLR7 agonist 4 (Compound 1.2) is a TLR7 agonist (EC50: 4.3 nM).
Formule :C₂₃H₃₄N₆O₃
Couleur et forme :Solid
Masse moléculaire :442.55
Ref: TM-T62587
+ Info
NT-0796
CAS :
- 2272917-13-0
NT-0796 is an inflammasome NLRP3 inhibitor that inhibits NLRP3 activation.NT-0796 is a potential NDT-19795 delivery vector.
Formule :C₂₃H₂₇N₃O₄
Degré de pureté :99.67%
Couleur et forme :Solid
Masse moléculaire :409.48
Ref: TM-T81637
+ Info
C5aR-IN-1
CAS :
- 2761048-02-4
C5aR-IN-1, a potent C5aR inhibitor, may aid in researching autoimmune and inflammatory diseases.
Formule :C₃₆H₃₉F₄N₃O₂
Couleur et forme :Solid
Masse moléculaire :621.71
Ref: TM-T73261
+ Info
Fendosal
CAS :
- 53597-27-6
Fendosal (HP-129), NSAID, 6.9-9.5x stronger than aspirin in chronic inflammation models.
Formule :C₂₅H₁₉NO₃
Degré de pureté :99.3%
Couleur et forme :Solid
Masse moléculaire :381.42
Ref: TM-T19967
+ Info
TMV-IN-5
CAS :
- 1207318-92-0
TMV-IN-5 (compound 1a) serves as an antiviral/antifungal agent, specifically targeting and inhibiting the assembly of the tobacco mosaic virus (TMV) by binding
Formule :C₂₂H₂₃N₃S
Couleur et forme :Solid
Masse moléculaire :361.5
Ref: TM-T79269
+ Info
TLR7/8 agonist 9
CAS :
- 2649170-17-0
TLR7/8 agonist 9 (Compound 25a), exhibiting EC50 values of 40 nM and 23 nM for hTLR7 and hTLR8 respectively, demonstrates anti-tumor properties and enhances the
Formule :C₂₀H₂₆N₆O
Couleur et forme :Solid
Masse moléculaire :366.46
Ref: TM-T79069
+ Info
Veledimex racemate
CAS :
- 755013-59-3
Veledimex racemate, the racemic form of veledimex, is an orally available, small-molecule ligand that activates the RheoSwitch Therapeutic System.
Formule :C₂₇H₃₈N₂O₃
Degré de pureté :98%
Couleur et forme :Solid
Masse moléculaire :438.6
Ref: TM-T13293
+ Info
Caspase-3 activator 1
Caspase-3 activator 1 (compound 4b), a Ru(III) metal complex, effectively inhibits gastric tumor growth and metastasis by mediating caspase-3 cleavage.
Formule :C₂₈H₂₇N₆O₂RuS₂
Degré de pureté :98%
Couleur et forme :Solid
Masse moléculaire :644.75
Ref: TM-T79743
+ Info
(S)-BI 665915
CAS :
- 1360550-05-5
(S)-BI 665915 is an orally active inhibitor of oxadiazole-containing 5-lipoxygenase-activating protein (FLAP)(IC50 of 1.7 nM for FLAP binding)..
Formule :C₂₄H₂₆N₈O₂
Degré de pureté :98%
Couleur et forme :Solid
Masse moléculaire :458.52
Ref: TM-T12793
+ Info
AD 0261
CAS :
- 145600-69-7
AD 0261 is a radical scavenger. It has a strong inhibitory action on the generation of lipid peroxides and superoxide anions.
Formule :C₂₇H₃₁F₂N₃O
Degré de pureté :98%
Couleur et forme :Solid
Masse moléculaire :451.55
Ref: TM-T10253
+ Info
STING agonist-10
CAS :
- 2259308-69-3
STING agonist-10 is a potent activator of the STING small molecule cyclic urea class (EC50: 2600 nM).STING activation is a highly promising immunotherapy.
Formule :C₂₅H₂₀ClF₄N₃O₂
Couleur et forme :Solid
Masse moléculaire :505.89
Ref: TM-T63457
+ Info
IKK-IN-1
CAS :
- 406211-06-1
IKK-IN-1 is an inhibitor of IKK.
Formule :C₂₂H₂₆ClN₃O₄
Degré de pureté :98%
Couleur et forme :Solid
Masse moléculaire :431.91
Ref: TM-T11633
+ Info
ACHP Hydrochloride
CAS :
- 406209-26-5
ACHP Hydrochloride (IKK-2 Inhibitor VIII) is a highly potent and selective IKK-β inhibitor with an IC50 of 8.5 nM.
Formule :C₂₁H₂₅ClN₄O₂
Degré de pureté :99.83%
Couleur et forme :Solid
Masse moléculaire :400.9
Ref: TM-T10237
+ Info
AHR antagonist 4
CAS :
- 2242465-58-1
AHR antagonist 4, potent with 82.2 nM IC50, inhibits AHR from patent WO2018146010A1 and shows anti-cancer properties.
Formule :C₂₀H₁₄F₆N₄O₄
Degré de pureté :98%
Couleur et forme :Solid
Masse moléculaire :488.34
Ref: TM-T10271
+ Info
BDW568
CAS :
- 335401-44-0
BDW568, a prodrug of BDW-OH, serves as a stimulator of interferon genes (STING) agonist.
Formule :C₁₂H₁₂N₄O₂S₂
Couleur et forme :Solid
Masse moléculaire :308.38
Ref: TM-T83901
+ Info
JNJ-67856633
CAS :
- 2230273-76-2
JNJ-67856633 is an orally active, first-in-class, potent, selective and allosteric inhibitor of MALT1 protease .
Formule :C₂₀H₁₁F₆N₅O₂
Degré de pureté :99.87%
Couleur et forme :Solid
Masse moléculaire :467.32
Ref: TM-T36670
+ Info
(Rac)-BAY-985
CAS :
- 2101925-20-4
(Rac)-BAY-985 is a potent, ATP-competitive and selective inhibitor of TBK1(IC50 of 1.5 nM),with antitumor efficacy.
Formule :C₂₇H₃₀F₃N₉O
Degré de pureté :98%
Couleur et forme :Solid
Masse moléculaire :553.58
Ref: TM-T12659
+ Info
TMV-IN-3
CAS :
- 2883408-35-1
TMV-IN-3 is a chalcone derivative that inhibits TMV with a 120.3 μg/mL EC50, used in research on infection and cancer.
Formule :C₂₈H₂₆O₄
Couleur et forme :Solid
Masse moléculaire :426.5
Ref: TM-T74713
+ Info
α-Pyridoin
CAS :
- 1141-05-5
α-Pyridoin (α-pyridoin) is an enediol (enediol) compound that acts as a unique antioxidant.
Formule :C₁₂H₁₂N₂O₂
Couleur et forme :Solid
Masse moléculaire :216.24
Ref: TM-T80703
+ Info
Lipid peroxidation inhibitor 1
CAS :
- 142873-41-4
Lipid peroxidation inhibitor 1 is an inhibitor of lipid peroxidation (IC50: 0.07 μM).
Formule :C₂₄H₃₂N₂O
Degré de pureté :98%
Couleur et forme :Solid
Masse moléculaire :364.52
Ref: TM-T10166
+ Info
GW274150 phosphate
CAS :
- 438542-15-5
GW274150 phosphate is a selective, orally active iNOS inhibitor with an IC50 of 0.2 μM. It mitigates experimental renal ischaemia-reperfusion injury.
Formule :C₈H₂₀N₃O₆PS
Degré de pureté :98%
Couleur et forme :Solid
Masse moléculaire :317.3
Ref: TM-T11518
+ Info
CCG-63802
CAS :
- 620112-78-9
CCG-63802 is a reversible small-molecule inhibitor of regulator of G protein signaling (RGS) proteins.
Formule :C₂₆H₁₈N₄O₂S
Degré de pureté :90%
Couleur et forme :Solid
Masse moléculaire :450.51
Ref: TM-T14897
+ Info
STING-IN-7
CAS :
- 899947-07-0
STING-IN-7 (compound 21) serves as a potent inhibitor of the stimulator of interferon genes (STING) pathway, demonstrating an inhibitory concentration (IC50) of
Formule :C₁₆H₁₄ClN₃O
Degré de pureté :98%
Couleur et forme :Solid
Masse moléculaire :299.76
Ref: TM-T81082
+ Info
MALT1-IN-6
CAS :
- 2254669-07-1
MALT1-IN-6 is a MALT1 protease inhibitor (Ki: 9 nM) that exhibits anticancer activity.
Formule :C₁₈H₁₂Cl₂F₃N₉O
Couleur et forme :Solid
Masse moléculaire :498.25
Ref: TM-T63372
+ Info
PROTAC IRAK4 degrader-8
CAS :
- 2911615-06-8
PROTAC IRAK4 Degrader-8 (Compound 2) is a PROTAC designed to target IRAK4 with an IC50 of 15.5 nM [1].
Formule :C₄₃H₅₀ClF₂N₁₁O₅
Degré de pureté :98%
Couleur et forme :Solid
Masse moléculaire :874.38
Ref: TM-T79097
+ Info
FEN1-IN-6
CAS :
- 824983-84-8
FEN1-IN-6 (compound 9) is a potent Flap endonuclease-1 (FEN1, IC50 = 10 nM) inhibitor, crucial for DNA damage repair in mammalian cells, and additionally
Formule :C₁₂H₈N₂O₅S₂
Degré de pureté :98%
Couleur et forme :Solid
Masse moléculaire :324.33
Ref: TM-T79134
+ Info
GSK840
CAS :
- 2361146-30-5
GSK840 (GSK'840) is a receptor-interacting protein kinase 3 (RIP3 or RIPK3) inhibitor, which binds the RIP3 kinase domain (IC50: 0.9 nM), and inhibits kinase
Formule :C₂₁H₂₃N₃O₃
Degré de pureté :99.7%
Couleur et forme :Solid
Masse moléculaire :365.43
Ref: TM-T11501
+ Info
Tyrosinase-IN-22
CAS :
- 25369-78-2
Tyrosinase-IN-22 (compound 4) serves as a potent inhibitor for tyrosinase substrates, namely L-tyrosine and L-dopa, exhibiting inhibitory concentrations (IC50s) of 60 nM and 30 nM, respectively. Additionally, it demonstrates significant antioxidant and anti-melanogenic properties, making it suitable for related research endeavors [1].
Formule :C₇H₅ClN₂S
Couleur et forme :Solid
Masse moléculaire :184.64
Ref: TM-T84705
+ Info
Anti-inflammatory agent 65
CAS :
- 3035442-58-8
Anti-inflammatory agent 65 (compound 29), a Hederagonic acid derivative, exhibits potent activity by inhibiting nitric oxide (NO) release, nuclear translocation
Formule :C₄₉H₇₁NO₆S₂
Degré de pureté :98%
Couleur et forme :Soild
Masse moléculaire :834.22
Ref: TM-T83047
+ Info
Factor D inhibitor 6
CAS :
- 1386455-51-1
Factor D inhibitor 6 is a potent, highly selective, and orally active compound that specifically inhibits the activity of factor D (FD) with an IC50 of 30 nM and a Kd of 6 nM. It does not exhibit inhibitory effects against factor B, classical and lectin complement-pathway activation, or a broad array of receptors, ion channels, kinases, and proteases.
Formule :C₂₃H₂₂ClFN₆O₃
Couleur et forme :Solid
Masse moléculaire :484.92
Ref: TM-T38803
+ Info
GW274150 dihydrochloride
CAS :
- 438542-17-7
GW274150 (dihydrochloride) is a potent, selective inhibitor of human and rat inducible nitric oxide synthase (iNOS), exhibiting oral activity and NADPH-
Formule :C₈H₁₉Cl₂N₃O₂S
Degré de pureté :98%
Couleur et forme :Solid
Masse moléculaire :292.23
Ref: TM-T82251
+ Info
TLR7 agonist 15
CAS :
- 2832199-53-6
TLR7 agonist 15 (compound 16b) is a potent activator of mouse macrophages and hPBMCs, demonstrating an EC50 of 18 nM.
Formule :C₂₆H₃₁N₅O
Couleur et forme :Solid
Masse moléculaire :429.56
Ref: TM-T79750
+ Info
CAY10464
CAS :
- 688348-37-0
CAY10464 (AHR antagonist 7) is an AHR antagonist for the study of cancer and metabolic diseases.
Formule :C₁₅H₁₂Cl₂O
Degré de pureté :99.96%
Couleur et forme :Solid
Masse moléculaire :279.16
Ref: TM-T84540
+ Info
IR-Crizotinib
CAS :
- 2387927-74-2
IR-Crizotinib is a conjugate of the near-infrared dye IR-786 and Crizotinib, an NF-κB-inducing kinase (NIK) inhibitor, with an IC50 of 3.381 μM for intracranial
Formule :C₅₃H₅₇Cl₂FIN₇O
Degré de pureté :98%
Couleur et forme :Solid
Masse moléculaire :1024.88
Ref: TM-T82049
+ Info
Cergutuzumab amunaleukin
CAS :
- 1509916-03-3
Cergutuzumab amunaleukin (CEA-IL2v) is a CEA-targeted IL-2 variant immunocytokine for combination cancer immunotherapy with anti-tumor activity.
Degré de pureté :98% (SDS-PAGE); 99.7% (SEC-HPLC) - 98% (SDS-PAGE); 99.7% (SEC-HPLC)
Couleur et forme :Liquid
Masse moléculaire :162.05 kDa
Ref: TM-T76944
+ Info
IL-17A antagonist 3
CAS :
- 2230780-65-9
IL-17A antagonist 3 is an IL-17A antagonist.
Formule :C₃₃H₃₃ClN₆O₄
Degré de pureté :98%
Couleur et forme :Solid
Masse moléculaire :613.11
Ref: TM-T11636
+ Info
RIPK1-IN-16
CAS :
- 2561431-77-2
RIPK1-IN-16 is an orally active, potent RIPK1 inhibitor that mitigates excessive inflammation via inhibition of RIPK1-mediated necroptosis in vivo.
Formule :C₂₀H₁₉N₅O₂S
Degré de pureté :98%
Couleur et forme :Solid
Masse moléculaire :393.46
Ref: TM-T81269
+ Info
STING agonist-11
CAS :
- 2259308-68-2
STING agonist-11 is a potent activator of the small molecule cyclic urea class of STING (EC50: 18 nM).STING activation is a highly promising immunotherapy.
Formule :C₂₅H₂₀ClF₄N₃O₂
Couleur et forme :Solid
Masse moléculaire :505.89
Ref: TM-T63458
+ Info
Oxidized ATP trisodium salt
CAS :
- 71997-40-5
Oxidized ATP trisodium salt (oATP) is a broad-spectrum inhibitor of P2 receptors, irreversibly antagonizing P2X7R activation and inhibiting c-reactive protein (
Formule :C₁₀H₁₁N₅Na₃O₁₃P₃
Degré de pureté :98%
Couleur et forme :Solid
Masse moléculaire :571.11
Ref: TM-T78639
+ Info
PDE4-IN-8
CAS :
- 2415085-45-7
PDE4-IN-8 is a potent PDE4 inhibitor with IC50 0.93 nM for PDE4B2 and minor impact on IL13, IL4, IFNy (IC50: 4.04, 36.33, 2394 nM).
Formule :C₁₈H₂₂BNO₄
Couleur et forme :Solid
Masse moléculaire :327.18
Ref: TM-T60920
+ Info
MKA031
CAS :
- 2951012-00-1
MKA031 (compound 6y) is a non-competitive inhibitor of macrophage migration inhibitory factor (MIF), exhibiting an IC50 of 1.7 μM.
Formule :C₂₁H₁₇N₅O₂S
Couleur et forme :Solid
Masse moléculaire :403.46
Ref: TM-T78716
+ Info
IRAK4-IN-6
CAS :
- 2454244-02-9
IRAK4-IN-6 is an oral IRAK4 inhibitor with a 4 nM IC50, targeting MyD88 L265P mutant DLBCL.
Formule :C₂₅H₃₂N₁₀O₂
Degré de pureté :98%
Couleur et forme :Solid
Masse moléculaire :504.59
Ref: TM-T11674
+ Info
TLR9-IN-1
CAS :
- 2226366-86-3
TLR9-IN-1: selective, potent human TLR9 inhibitor (IC50: 7 nM), useful for researching immune-related diseases.
Formule :C₂₃H₃₁N₇O
Couleur et forme :Solid
Masse moléculaire :421.54
Ref: TM-T62254
+ Info
Leteprinim
CAS :
- 138117-50-7
Leteprinim (AIT 082 acid) is an hypoxanthine derivative that stimulates in vitro neurite outgrowth and the production of adenosine and neurotrophins from
Formule :C₁₅H₁₃N₅O₄
Degré de pureté :99.08%
Couleur et forme :Solid
Masse moléculaire :327.29
Ref: TM-T32658L
+ Info
FEN1-IN-7
CAS :
- 824983-90-6
FEN1-IN-7 (compound 16), a selective Flap endonuclease-1 (FEN1) inhibitor with an IC50 of 18 nM, plays a role in DNA damage repair in mammalian cells.
Formule :C₁₆H₁₄N₂O₆S
Degré de pureté :98%
Couleur et forme :Solid
Masse moléculaire :362.36
Ref: TM-T79135
+ Info
Ginsenoside Rk1
CAS :
- 494753-69-4
Ginsenoside Rk1 is a component created by processing the ginseng plant at high temperatures.
Formule :C₄₂H₇₀O₁₂
Degré de pureté :98.46% - 99.13%
Couleur et forme :Solid
Masse moléculaire :767
Ref: TM-T4S1499
+ Info
WEHI-345
CAS :
- 1354825-58-3
WEHI-345 is a potent and selective RIPK2 inhibitor which shows NOD signalling events yet prevents inflammatory cytokine production.
Formule :C₂₂H₂₃N₇O
Degré de pureté :>99.99%
Couleur et forme :Solid
Masse moléculaire :401.46
Ref: TM-T3997
+ Info
GGTI 2147
CAS :
- 191102-87-1
GGTI 2147 decreased Rac1 activity, down-regulated p65 expression, and ameliorated OGD/R-induced neuronal apoptosis.
Formule :C₂₈H₃₀N₄O₃
Degré de pureté :98.69%
Couleur et forme :Solid
Masse moléculaire :470.56
Ref: TM-T25450
+ Info
BRP-201
CAS :
- 2227434-74-2
BRP-201: selective mPGES-1 inhibitor (IC50: 0.42 μM), potential next-gen anti-inflammatory drug.
Formule :C₂₈H₂₇ClN₄OS
Couleur et forme :Solid
Masse moléculaire :503.06
Ref: TM-T63424
+ Info
Vipoglanstat
CAS :
- 1360622-01-0
Vipoglanstat: inhibits prostaglandin E synthase, anti-inflammatory, reduces leukocyte infiltration and lung injury from endotoxin/sepsis.
Formule :C₃₀H₃₄Cl₂F₅N₅O₃
Couleur et forme :Solid
Masse moléculaire :678.52
Ref: TM-T70874
+ Info
FEN1-IN-5
CAS :
- 824983-93-9
FEN1-IN-5 (compound 12A) is a potent Flap endonuclease-1 (FEN1) inhibitor with an IC50 value of 12 nM, playing a role in DNA repair mechanisms [1].
Formule :C₂₁H₁₇N₃O₄S
Degré de pureté :98%
Couleur et forme :Solid
Masse moléculaire :407.44
Ref: TM-T78192
+ Info
EG01377
CAS :
- 2227996-00-9
EG01377 is a NRP1 antagonist with antiangiogenic, antimigratory, and antitumor activity, Kd 1.32 μM, IC50s 609 nM for NRP1-a1/b1, inactive on NRP2.
Formule :C₂₆H₃₀N₆O₆S₂
Degré de pureté :98%
Couleur et forme :Solid
Masse moléculaire :586.68
Ref: TM-T11154
+ Info
TLR7 agonist 16
CAS :
- 2832199-56-9
TLR7 agonist 16 (compound 16d) is a potent activator of TLR7 with an EC50 value of 18 nM.
Formule :C₂₅H₂₉N₅O₂
Couleur et forme :Solid
Masse moléculaire :431.53
Ref: TM-T79751
+ Info
STING modulator-3
CAS :
- 2839639-94-8
STING modulator-3, a 43.1 nM R232 STING inhibitor, doesn't affect IRF-3 or TNF-β in THP-1 cells.
Formule :C₁₈H₁₇N₉O
Couleur et forme :Solid
Masse moléculaire :375.39
Ref: TM-T72614
+ Info
cGAS-IN-1
CAS :
- 858770-07-7
cGAS-IN-1 (compound C20), a flavonoid that acts as a Cyclic GMP-AMP Synthase (cGAS) inhibitor, demonstrates IC50 values of 2.28 μM for human cGAS and 1.44 μM
Formule :C₁₈H₁₉NO₈
Couleur et forme :Solid
Masse moléculaire :377.35
Ref: TM-T78858
+ Info
Nrf2-IN-3
CAS :
- 6325-13-9
Nrf2-IN-3 is an NRF2 inhibitor that selectively sensitizes xenografts of mouse mKEAP1 cancer cells to cisplatin.
Formule :C₂₂H₂₆N₄O₄S
Degré de pureté :98.07%
Couleur et forme :Solid
Masse moléculaire :442.53
Ref: TM-T78841
+ Info
ABR-238901
CAS :
- 1638200-22-2
ABR-238901 is an oral, active S100A8/A9 blocker that inhibits the interaction of S100A8/A9 with its receptors RAGE(receptor for advanced glycation end products
Formule :C₁₁H₉BrClN₃O₄S
Degré de pureté :98.63% - 98.71%
Couleur et forme :Solid
Masse moléculaire :394.63
Ref: TM-T39115
+ Info
LTβR-IN-1
CAS :
- 2189366-77-4
LTβR-IN-1 is a potent and selective lymphin β receptor (LTβR) inhibitor.
Formule :C₁₈H₁₆N₄O₂
Degré de pureté :98.93%
Couleur et forme :Solid
Masse moléculaire :320.35
Ref: TM-T11886
+ Info
Iptacopan
CAS :
- 1644670-37-0
Iptacopan (LNP023) is an inhibitor with high affinity to factor B, with a KD value of 7.9 nM and an IC50 value of 10 nM. Cost-effective and quality-assured.
Formule :C₂₅H₃₀N₂O₄
Degré de pureté :99.07% - >99.99%
Couleur et forme :Solid
Masse moléculaire :422.52
Ref: TM-T11864
+ Info
Xanthine oxidase-IN-10
CAS :
- 851429-65-7
Xanthine oxidase-IN-10 (XO8 analog) is a xanthine oxidase (XO) inhibitor for the study of gout.
Formule :C₁₀H₈N₂OS
Degré de pureté :99.16%
Couleur et forme :Solid
Masse moléculaire :204.25
Ref: TM-T78984
+ Info
AVP-13358
CAS :
- 459805-03-9
AVP-13358: a CD23/IgE inhibitor for treating immune, infection, and ENT disorders.
Formule :C₃₀H₂₉N₅O₂
Degré de pureté :98.42%
Couleur et forme :Solid
Masse moléculaire :491.58
Ref: TM-T30231
+ Info
ERDRP-0519
CAS :
- 1374006-96-8
ERDRP-0519 is an oral measles polymerase inhibitor, preventing disease in monkeys, with potent nanomolar efficacy against morbilliviruses.
Formule :C₂₃H₃₀F₃N₅O₄S
Degré de pureté :98.64% - 98.71%
Couleur et forme :Solid
Masse moléculaire :529.58
Ref: TM-T24040
+ Info
CU-CPD107
CAS :
- 2573912-32-8
CU-CPD107 selectively activates TLR8 and ssRNA, inhibits TLR8 with R848 (IC50=13.7 μM), and coactivates with ssRNA.
Formule :C₁₆H₂₁IN₂O₂
Degré de pureté :98%
Couleur et forme :Solid
Masse moléculaire :400.25
Ref: TM-T35349
+ Info
Sembragiline
CAS :
- 676479-06-4
Sembragiline (EVT-302) is a selective MAO-B inhibitor for the study of Alzheimer's disease (AD).
Formule :C₁₉H₁₉FN₂O₃
Degré de pureté :99.49% - 99.49%
Couleur et forme :Solid
Masse moléculaire :342.36
Ref: TM-T28750
+ Info
RIPK1-IN-4
CAS :
- 1481641-08-0
RIPK1-IN-4 is a potent and selective type II kinase receptor interacting protein 1 (RIP1) kinase inhibitor and binds to a DLG-out inactive form of RIP1 (IC50s
Formule :C₂₃H₂₃N₅O₂
Degré de pureté :99.94%
Couleur et forme :Solid
Masse moléculaire :401.46
Ref: TM-T12730
+ Info
Netakimab
CAS :
- 1796570-08-5
Netakimab (BCD 085) is a monoclonal antibody targeting interleukin-17A and can be used to study spondyloarthritis.
Degré de pureté :95%
Couleur et forme :Liquid
Masse moléculaire :145.74 kDa
Ref: TM-T77098
+ Info
GW274150
CAS :
- 210354-22-6
GW274150: selective oral iNOS inhibitor (Kd=40 nM), low activity on eNOS/nNOS, protective in acute lung injury.
Formule :C₈H₁₇N₃O₂S
Degré de pureté :96.43%
Couleur et forme :Solid
Masse moléculaire :219.3
Ref: TM-T11518L
+ Info
IL-17 modulator 4
CAS :
- 2446803-65-0
IL-17 modulator 4 is a prodrug of IL-17 modulator 1, which acts as a potent modulator of IL-17.Cost-effective and quality-assured.
Formule :C₂₇H₃₄N₆O₂
Degré de pureté :99.59%
Couleur et forme :Solid
Masse moléculaire :474.6
Ref: TM-T36526
+ Info
Piflufolastat
CAS :
- 1423758-00-2
Piflufolastat (DCFPYL) is a PET imaging agent for prostate cancer PSMA.
Formule :C₁₈H₂₃FN₄O₈
Degré de pureté :98.98%
Couleur et forme :Solid
Masse moléculaire :442.4
Ref: TM-T31224
+ Info
Antiviral agent 34
CAS :
- 945152-88-5
Antiviral Agent 34 is an antiviral compound that inhibits influenza virus and inhibits the proliferation of influenza virus by modulating RNA polymerase.
Formule :C₂₉H₃₃N₃O₂S
Degré de pureté :99.51%
Couleur et forme :Soild
Masse moléculaire :487.66
Ref: TM-T77632
+ Info
Usnoflast
CAS :
- 2455519-86-3
Usnoflast (ZYIL1) is an NLRP3 inhibitor, inhibiting NLRP3 inflammasome activation, used in neurological disease research.
Formule :C₂₁H₂₉N₃O₃S
Degré de pureté :98.79%
Couleur et forme :Solid
Masse moléculaire :403.54
Ref: TM-T79864
+ Info
Supercinnamaldehyde
CAS :
- 70351-51-8
Supercinnamaldehyde is a potent activator of transient receptor potential ankyrin 1 (TRPA1), exhibiting an EC50 of 0.8 μM, and induces activation of TRPA1 ion
Formule :C₁₂H₁₁NO₂
Degré de pureté :98.89%
Couleur et forme :Solid
Masse moléculaire :201.22
Ref: TM-T78082
+ Info
GB1107
CAS :
- 1978336-61-6
GB1107 is an effective and selective Galectin-3 inhibitor with a Kd of 37 nM.
Formule :C₂₀H₁₆Cl₂F₃N₃O₄S
Degré de pureté :98.33% - 99.87%
Couleur et forme :Solid
Masse moléculaire :522.32
Ref: TM-T15372
+ Info
Oditrasertib
CAS :
- 2252271-93-3
Oditrasertib, a RIPK1 inhibitor characterized by an IC50 value below 100 nM, is employed in inflammation research.
Formule :C₁₄H₁₅F₂N₃O₂
Degré de pureté :98.65% - 99.65%
Couleur et forme :Solid
Masse moléculaire :295.28
Ref: TM-T69726
+ Info
ADS032
CAS :
- 2757333-37-0
ADS032 (BT-032) is an NLRP1 and NLRP3 inhibitor with anti-inflammatory activity for the study of respiratory inflammation or infection.
Formule :C₂₂H₂₉NO₄S
Degré de pureté :98.37%
Couleur et forme :Solid
Masse moléculaire :403.54
Ref: TM-T79906
+ Info
(±)-CPSI-1306
CAS :
- 1309793-47-2
(±)-CPSI-1306 (2-(3-(2,4-Difluorophenyl)-4,5-dihydroisoxazol-5-yl)-1-morpholinoethan-1-one) is a macrophage migration inhibitory factor (MIF) antagonist and can
Formule :C₁₅H₁₆F₂N₂O₃
Degré de pureté :97.46%
Couleur et forme :Solid
Masse moléculaire :310.3
Ref: TM-T17315
+ Info
COX-2/15-LOX-IN-5
CAS :
- 443790-30-5
COX-2/15-LOX-IN-5 (Compound 4f) functions as a dual inhibitor of COX-2 and 15-LOX, demonstrating both anti-inflammatory and antioxidant properties [1]. This compound effectively reduces NF-κB activation in RAW 264.7 macrophages that is induced by lipopolysaccharide.
Formule :C₂₅H₂₁N₃O₃S
Couleur et forme :Solid
Masse moléculaire :443.52
Ref: TM-T86081
+ Info
MG-T-19
CAS :
- 328540-44-9
MG-T-19, a TIM-3 inhibitor, inhibit the interaction of TIM-3 with PtdSer, CEACAM1, and Gal-9, and increased the production of TNF-α and IFN-γ in PBMCs.
Formule :C₁₈H₈Br₂ClF₃N₄O₂S
Degré de pureté :99.14%
Couleur et forme :Solid
Masse moléculaire :596.6
Ref: TM-T201721
+ Info
CVN293
CAS :
- 2815296-08-1
CVN293 is a inhibitor of the potassium channel KCNK13,BBB,It inhibits the production of the pro-inflammatory cytokine IL-1β induced by NLRP3 in microglia
Formule :C₁₄H₁₀FN₇O
Degré de pureté :99.50%
Couleur et forme :Solid
Masse moléculaire :311.27
Ref: TM-T86109
+ Info
Heme Oxygenase-1-IN-2
Heme Oxygenase-1-IN-2 is a novel inhibitor of heme oxygenase-1 (HO-1), displaying potent antiproliferative activity in vitro, with an IC50 value of 0.95 μM.
Formule :C₁₉H₁₈ClN₃O
Couleur et forme :Solid
Masse moléculaire :339.82
Ref: TM-T61078
+ Info
C-di-IMP
CAS :
- 79940-41-3
Cyclic-di-IMP (C-di-IMP), a STING agonist, serves as a research tool in tumor studies.
Formule :C₂₀H₂₂N₈O₁₄P₂
Couleur et forme :Solid
Masse moléculaire :660.38
Ref: TM-T73362
+ Info
NLRP3-IN-80
CAS :
- 2842014-94-0
NLRP3-IN-80 (Compound 1) is an NLRP3 inhibitor useful for research into inflammatory aging.
Formule :C₂₄H₂₂F₂N₄O₃
Couleur et forme :Solid
Masse moléculaire :452.45
Ref: TM-T207648
+ Info
Galectin-3-IN-3
CAS :
- 2491661-50-6
Galectin-3-IN-3 (Compound 4) serves as a selective and orally active inhibitor targeting Gal-3. It exhibits IC50 values of 11 nM for mGal-3 and 84 nM for hGal-3 [1].
Formule :C₂₅H₂₂ClF₂N₇O₄S
Couleur et forme :Solid
Masse moléculaire :590.00
Ref: TM-T86486
+ Info
MMG-11 quarterhydrate
MMG-11 quarterhydrate, a potent hTLR2 antagonist, inhibits TLR2/1 and TLR2/6 with IC50s of 1.7μM and 5.7μM; low toxicity.
Formule :C₁₅H₁₆O₈
Couleur et forme :Solid
Masse moléculaire :310.78
Ref: TM-T60763
+ Info
PB01
CAS :
- 368434-78-0
PB01 is a DPP-4 inhibitor with an IC50 of 15.66 nM. It effectively suppresses high glucose-induced ROS generation and mitochondrial superoxide production while significantly reducing the cellular expression of DPP-4. Additionally, PB01 notably lowers blood glucose levels in diabetic mice. It demonstrates excellent safety, exhibiting almost no cytotoxicity at a concentration of 100 μM. PB01 holds promise for research in the diabetes field.
Formule :C₁₈H₂₁N₅O₃
Couleur et forme :Solid
Masse moléculaire :355.391
Ref: TM-T204296
+ Info
ALR-6
CAS :
- 6621-92-7
ALR-6, an antagonist of the 5-lipoxygenase (5-LOX) activating protein FLAP, possesses anti-inflammatory properties. It significantly inhibits 5-LOX product formation (>80%) in pro-inflammatory M1-MDM without substantially affecting direct inhibition of 5-LOX [1].
Formule :C₁₈H₁₄O₅
Couleur et forme :Solid
Masse moléculaire :310.3
Ref: TM-T85639
+ Info
AhR agonist 7
CAS :
- 3033281-98-7
Compound 8, an AhR agonist 7, demonstrates potent activation of AhR with an EC50 of 13nM [1].
Formule :C₁₆H₁₅ClFNO₂
Couleur et forme :Solid
Masse moléculaire :307.75
Ref: TM-T85606
+ Info
(Rel)-Factor B-IN-5
CAS :
- 2760789-22-6
(Rel)-Factor B-IN-5 is a complement factor B inhibitor that can be used to study diseases associated with activation of the alternative complement pathway.
Formule :C₂₇H₃₂N₂O₄
Degré de pureté :>99.99%
Couleur et forme :Solid
Masse moléculaire :448.55
Ref: TM-T62689
+ Info
COX-2-IN-12
COX-2-IN-12: Potent, selective COX-2 inhibitor, IC50=19.98μM, safe anti-inflammatory with low acute toxicity.
Formule :C₁₇H₁₉NO₃
Couleur et forme :Solid
Masse moléculaire :285.34
Ref: TM-T60566
+ Info
XO/COX/LOX-IN-1
XO/COX/LOX-IN-1 targets XO/COX/LOX, used in research of inflammation, cancer, and metabolic disorders.
Formule :C₂₄H₂₀N₄O₂S
Couleur et forme :Solid
Masse moléculaire :428.51
Ref: TM-T62350
+ Info
Ac5GalNTGc
CAS :
- 1334320-77-2
Ac5GalNTGc, an analog of hexosamine, inhibits mucin-type O-linked glycosylation biosynthesis [1].
Formule :C₁₈H₂₅NO₁₁S
Couleur et forme :Solid
Masse moléculaire :463.46
Ref: TM-T85546
+ Info
Factor B-IN-4
CAS :
- 2760669-84-7
Factor B-IN-4 is a potent inhibitor (IC50: 1 μM) of complement factor B. Factor B-IN-4 can be used to study inflammatory and immune-related diseases.
Formule :C₂₇H₃₂N₂O₄
Couleur et forme :Solid
Masse moléculaire :448.55
Ref: TM-T62688
+ Info
Polvitolimod
CAS :
- 2389988-81-0
Polvitolimod is a TLR7 agonist used to treat infectious disease and cancer.
Formule :C₁₃H₁₄FN₅O₄
Couleur et forme :Solid
Masse moléculaire :323.28
Ref: TM-T60875
+ Info
ODN 2088
CAS :
- 1146541-45-8
ODN 2088 is a potent inhibitor of TLR3, TLR7 and TLR9 that is non-cytotoxic and shows inhibition of the release of IFN-α and IL-6.
Couleur et forme :Solid
Ref: TM-T64278
+ Info
TLR7/8 antagonist 2
TLR7/8 antagonist 2: potent, orally active, IC50: 4.9 nM (TLR7), 0.6 nM (TLR8); potential for lupus therapy research.
Formule :C₂₂H₂₆FN₅
Couleur et forme :Solid
Masse moléculaire :379.47
Ref: TM-T61601
+ Info
YE6144
CAS :
- 3065657-02-2
YE6144, IRF5 phosphorylation blocker. Affordable Excellence: Reliable Quality You Can Trust
Formule :C₂₁H₂₇ClFN₇O
Couleur et forme :Solid
Masse moléculaire :447.94
Ref: TM-T62678
+ Info
Anti-inflammatory agent 10
Tilomisole-derived benzimidazole-thiazole, orally active, favors COX-2 inhibition over COX-1.
Formule :C₁₇H₁₃BrN₄O₃S₂
Couleur et forme :Solid
Masse moléculaire :465.34
Ref: TM-T62967
+ Info
COX-2-IN-13
COX-2-IN-13 is a potent, selective COX-2 inhibitor with 0.98 μM IC50; shows strong anti-inflammatory properties and low acute toxicity.
Formule :C₁₉H₁₈N₂O₅S
Couleur et forme :Solid
Masse moléculaire :386.42
Ref: TM-T61714
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Galectin-3-IN-4
CAS :
- 2496515-38-7
Galectin-3-IN-4 (compound 5), a carboxamide analog, effectively and selectively inhibits both human and mouse galectin-3. This compound demonstrates notable potency with IC50 values of 21 nM for hGal-3 and 167 nM for mGal-3. It is also orally bioavailable. For other galectins, Galectin-3-IN-4 shows IC50 values of 1580 nM for hGal-1 and 2750 nM for hGal-9, respectively [1].
Formule :C₂₄H₂₂ClF₂N₅O₅S
Couleur et forme :Solid
Masse moléculaire :565.98
Ref: TM-T86487
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IKZF1-degrader-1
CAS :
- 2915586-02-4
IKZF1-degrader-1 (Compound 9-B) serves as a potent degrader of the IKZF1 protein, exhibiting a DC50 of 0.134 nM. It is applicable in the degradation of tumors [1].
Formule :C₃₅H₂₉F₂N₅O₃
Couleur et forme :Solid
Masse moléculaire :605.63
Ref: TM-T86707
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Corannulene
CAS :
- 5821-51-2
Corannulene is an agonist of the aromatic hydrocarbon receptor (AhR). It induces a lower cytotoxic response in liver cancer cells compared to Benzo[a]pyrene and shows potential for use in cancer research.
Formule :C₂₀H₁₀
Couleur et forme :Solid
Masse moléculaire :250.293
Ref: TM-T204413
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AS2690168 hydrochloride
CAS :
- 1393899-47-2
AS2690168 hydrochloride is an orally active inhibitor of RANKL signaling that can suppress RANKL-induced osteoclastogenesis in RAW264 cells. AS2690168 is applicable in research related to pathological bone resorption.
Formule :C₁₇H₁₅Cl₂F₃N₄O
Couleur et forme :Solid
Masse moléculaire :419.228
Ref: TM-T204813
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MAY0132
CAS :
- 1895861-88-7
MAY0132 is a potent and selective EPAC2 inhibitor with an IC50 of 0.4 μM. It significantly inhibits the replication of HMPV, AdV, and RSV, reduces cytokine/chemokine production induced by viral infections, and suppresses NF-κB activation. MAY0132 exhibits antiviral activity and can be used in respiratory virus infection research.
Formule :C₁₆H₁₅ClF₃N
Couleur et forme :Solid
Masse moléculaire :313.745
Ref: TM-T204630