Immunologie et Inflammation
Les inhibiteurs en immunologie et inflammation sont des composés qui modulent la réponse immunitaire et les processus inflammatoires. Ces inhibiteurs sont cruciaux pour étudier les mécanismes de la régulation immunitaire, l'auto-immunité et l'inflammation chronique, ainsi que pour développer des traitements pour les maladies inflammatoires, les allergies et les troubles immunitaires. En ciblant des voies clés du système immunitaire, ces inhibiteurs peuvent aider à réduire les réponses immunitaires excessives ou inappropriées. Chez CymitQuimica, nous offrons une large sélection d'inhibiteurs de haute qualité en immunologie et inflammation pour soutenir vos recherches en immunologie, inflammation et développement thérapeutique.
Sous-catégories appartenant à la catégorie "Immunologie et Inflammation"
- RCC(136 produits)
- CXCR(147 produits)
- Paroi cellulaire(5 produits)
- Récepteur IL(113 produits)
- IκB/IKK(61 produits)
- LTR(3 produits)
- MALT(23 produits)
- MRP(6 produits)
- NADPH-oxydase(1 produits)
- NF-κB(445 produits)
- NOD(17 produits)
- NOS(63 produits)
- Nrf2(78 produits)
- PGE Synthase(31 produits)
- ROS(69 produits)
- TGF-beta/Smad(58 produits)
- TLR(66 produits)
- Thioredoxine(12 produits)
- gp120/CD4(4 produits)
Affichez 11 plus de sous-catégories
3035 produits trouvés pour "Immunologie et Inflammation"
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L 012 sodium salt
CAS :<p>L 012 sodium salt: chemiluminescent probe for oxygen & nitrogen detection; identifies superoxides & Nox inhibitors.</p>Formule :C13H8ClN4NaO2Degré de pureté :98.08% - 98.70%Couleur et forme :SolidMasse moléculaire :310.67Temtokibart
CAS :<p>Temtokibart is a humanized monoclonal antibody targeting IL22RA1, used in autoimmune and inflammatory disease research.</p>Couleur et forme :LiquidMasse moléculaire :145.5TMV-IN-6
<p>TMV-IN-6 (Compound 4g) serves as a novel antiviral and fungicidal agent that impedes tobacco mosaic virus (TMV) assembly, functioning by attachment to TMV coat</p>Formule :C29H27N3OSCouleur et forme :SolidMasse moléculaire :465.613-Methoxycatechol
CAS :<p>3-Methoxycatechol: lignin-based, esophageal carcinogen. 1,2-Dihydroxy-3-methoxybenzene: potent anti-EMCV.</p>Formule :C7H8O3Degré de pureté :99.31%Couleur et forme :SolidMasse moléculaire :140.14Oleclumab
CAS :<p>Oleclumab (MEDI9447) is a human anti-CD73 monoclonal antibody with anticancer activity for the study of metastatic desmoplastic resistant prostate cancer.</p>Degré de pureté :95%Couleur et forme :LiquidMasse moléculaire :143.14 kDa4-methyl-6-phenyl-2H-pyranone
CAS :<p>4-methyl-6-phenyl-2H-pyranone from Scutellaria boosts mitochondria, shields astrocytes from peroxide.</p>Formule :C12H10O2Degré de pureté :>99.99%Couleur et forme :SolidMasse moléculaire :186.21Antidesmone
CAS :<p>Antidesmone from Ajuga decumbens inhibits acute lung injury by modulating MAPK and NF-κB.</p>Formule :C19H29NO3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :319.44EPI-589
CAS :<p>EPI-589, a quinone oxidoreductase inhibitor, may treat ALS; it's safe and tolerable.</p>Formule :C14H19NO4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :265.31IFN-α Receptor Recognition Peptide 1
CAS :<p>IFN-α Receptor Recognition Peptide 1, associated with receptor interactions, is a peptide of IFN-α.</p>Formule :C35H59N13O12SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :885.99Interleukin II (60-70)
<p>Interleukin 2 (IL-2) peptide: NH2-LEU-THR-PHE-LYS-PHE-TYR-MET-PRO-LYS-LYS-ALA-COOH, MW 1373.7, immune cytokine.</p>Formule :C68H104N14O14S1Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1373.7TLR8 agonist 2 hydrochloride
CAS :<p>TLR8 agonist 2 hydrochloride: potent for human TLR8 (EC50 3 nM), weak for TLR7 (EC50 33.33 μM).</p>Formule :C16H22N8·xHClCouleur et forme :SolidEritoran
CAS :<p>Eritoran: TLR4 antagonist; shields mice from lethal influenza, EBOV, MARV; reduces granulocytosis, eases cytokine storm.</p>Formule :C66H126N2O19P2Couleur et forme :SolidMasse moléculaire :1313.66Bivalirudin TFA
CAS :<p>Bivalirudin TFA, a 20-residue synthetic peptide, reversibly inhibits thrombin, affecting platelet aggregation and thrombin generation.</p>Formule :C98H138N24O33·C2HF3O2Couleur et forme :SolidMasse moléculaire :2294.34Efmarodocokin alfa
CAS :<p>Efmarodocokin alfa, IL-22/IgG4 fusion protein, activates IL-22 pathways, researched for severe COVID-19 pneumonia.</p>Couleur et forme :Liquid3-Hydroxykynurenamine
CAS :<p>3-Hydroxykynurenamine (3-HKA) is a tryptophan metabolite with anti-inflammatory effects, reducing cytokines and aiding in models of psoriasis and nephritis.</p>Formule :C9H12N2O2Couleur et forme :SolidMasse moléculaire :180.2BMS-986235
CAS :<p>BMS-986235 (LAR-1219), an oral FPR2 agonist, EC50: 0.41 nM (hFPR2), 3.4 nM (mFPR2), may prevent heart failure.</p>Formule :C18H17F2N3O3Degré de pureté :99.85%Couleur et forme :SolidMasse moléculaire :361.34FITC-labeled ODN 1668 sodium
<p>FITC-labeled ODN 1668 (sodium), a class B CpG oligodeoxynucleotide (ODN), functions as a TLR9 agonist.</p>Couleur et forme :Odour SolidCP-289
CAS :<p>CP-289 is a potent C5a receptor antagonist with IC50 of 1 μM.</p>Formule :C30H35ClN2O2Degré de pureté :99.97%Couleur et forme :SoildMasse moléculaire :491.06Gp100 (25-33), human
CAS :<p>Gp100 (25-33), human: 9-AA melanoma antigen fragment, H-2Db restricted, T-cell recognized, targets B16 melanoma.</p>Formule :C52H82N16O14Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1155.31Brivestobart
<p>Brivestobart is a humanized IgG4κ antibody that targets LAG3, accompanied by an isotype control designated as HumanIgG4(S228P) kappa, Isotype Control.</p>Couleur et forme :Odour LiquidIbritumomab
<p>Ibritumomab is a murine-derived anti-CD20 monoclonal antibody that kills tumor cells by forming free radicals in target cells and surrounding tissues.</p>Degré de pureté :96% (SDS-PAGE); 95.9% (SEC-HPLC) - 96% (SDS-PAGE); 95.9% (SEC-HPLC)Couleur et forme :Odour LiquidPSMA-DA1
CAS :<p>PSMA–DA1 may be a useful PSMA-targeting radiotheranostic agent.</p>Formule :C50H76IN9O20Couleur et forme :SolidMasse moléculaire :1250.105Salicortin
CAS :<p>Salicortin, a phenolic glycoside from Populus and Salix, has anti-adipogenic, anti-amnesic, and immune effects.</p>Formule :C20H24O10Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :424.40Biotin-labeled ODN 1826 sodium
<p>Biotin-labeled ODN 1826 (sodium), a class B CpG oligodeoxynucleotide (ODN), serves as a TLR9 agonist and facilitates assessment of CpG ODN cellular uptake and</p>Couleur et forme :Odour SolidTuparstobart
CAS :<p>Tuparstobart (Incagn-02385) is an IgG1κ monoclonal antibody that targets the immune checkpoint receptor protein LAG-3, which is predominantly expressed on</p>Couleur et forme :LiquidBiotinoyl tripeptide-1
CAS :<p>Biotinoyl tripeptide-1 can produce hair follicles by promoting scalp micro-circulation and reduce follicle atrophy and aging.</p>Formule :C24H38N8O6SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :566.673-O-(2'E,4'Z-Decadienoyl)ingenol
<p>3-O-(2'E,4'Z-Decadienoyl)ingenol is a useful organic compound for research related to life sciences and the catalog number is T124104.</p>Formule :C30H42O6Couleur et forme :SolidMasse moléculaire :498.66Bectumomab
CAS :<p>Bectumomab (IMMU-LL2) is a humanized IgG2a mAb targeting CD22, used in imaging and staging non-Hodgkin's lymphoma.</p>Couleur et forme :Liquid2-Hydroxybenzylamine
CAS :<p>2-Hydroxybenzylamine captures IsoLGs, prevents early atrial fibrillation recurrence post-ablation.</p>Formule :C7H9NODegré de pureté :95.93%Couleur et forme :CoaMasse moléculaire :123.15Inflexuside A
CAS :<p>Inflexuside A, an abietane diterpenoid from Isodon inflexus, and Inflexuside B inhibit NO in LPS-stimulated RAW264.7 cells.</p>Formule :C26H42O9Couleur et forme :SolidMasse moléculaire :498.61Nrf2 activator-8
<p>Nrf2 Activator-8 (Compound 10e), with an EC50 of 37.9 nM, is a potent Nrf2 activator that demonstrates significant antioxidant and anti-inflammatory properties</p>Formule :C13H11ClN2O3SCouleur et forme :SolidMasse moléculaire :310.76NOD1-RIPK2-IN-1
<p>NOD1-RIPK2-IN-1 (Compound 37) is an inhibitor of the NOD1-RIPK2 signaling pathway, displaying potent IC50 values of 42 nM and 1.52 nM against NOD1 and RIPK2, respectively. This compound effectively reduces the secretion of the pro-inflammatory cytokine IL-8, making it valuable for research in inflammation and immune disorders.</p>Formule :C22H26Cl2N4O3Couleur et forme :SolidMasse moléculaire :465.37Ansipastobart
<p>Ansipastobart is a humanized IgG1λ2 monoclonal antibody targeting NT5E, with HumanIgG1lambda2, Isotype Control serving as its isotype control.</p>Couleur et forme :Odour LiquidOVA Peptide(257-264) TFA
CAS :<p>OVA Peptide (257-264) TFA, an octameric peptide epitope from ovalbumin, is presented by the class I MHC molecule, H-2Kb, showcasing a class I (Kb)-restricted</p>Formule :C47H75F3N10O15Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1077.15SARS-CoV-2-IN-39
CAS :<p>SARS-CoV-2-IN-39 is a SARS-CoV-2 inhibitor with an EC50 of 1 μM.</p>Formule :C14H8ClF4NO3Degré de pureté :99.86%Couleur et forme :SoildMasse moléculaire :349.66His-Pro
CAS :<p>His-Pro is a dipeptide consisting of histidyl and proline.</p>Formule :C11H16N4O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :252.27Calcitriol Impurities D
CAS :<p>Calcitriol Impurities D: Vitamin hormone, promotes cell differentiation, has bone activity, inhibits HIV, and aids in treating AIDS/viral infections.</p>Formule :C28H46O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :430.66N-decanoyl-L-Homoserine lactone
CAS :<p>C10-HSL, an AHL from Pseudomonas cremoris ND07, stunts Arabidopsis roots by raising Ca2+, ROS, MPK6 activity, and NO levels.</p>Formule :C14H25NO3Degré de pureté :99.81%Couleur et forme :SolidMasse moléculaire :255.35STING agonist-17
CAS :<p>STING agonist-17 (compound 4a) is a highly potent stimulator of the STING pathway, exhibiting an IC 50 of 0.062 nM.</p>Formule :C43H53N13O8Couleur et forme :SolidMasse moléculaire :879.96CP-447697
CAS :<p>CP-447697, a lipophilic C5a receptor antagonist, exhibits an IC50 of 31 nM. It is utilized in inflammation research.</p>Formule :C29H26ClF2N3O2SDegré de pureté :99.90%Couleur et forme :SoildMasse moléculaire :554.05CD22 ligand-1
CAS :<p>CD22 ligand-1 is a potent, selective hCD22 binder (K D 0.335 µM) with potential for B-cell disease research.</p>Formule :C33H34N5NaO10Couleur et forme :SolidMasse moléculaire :683.64Glutaminase C-IN-2
<p>Glutaminase C-IN-2 (compound 11), an allosteric inhibitor of glutaminase C (GAC), exhibits potent inhibitory activity with an IC50 of 10.64 nM.</p>Formule :C24H23N7O2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :473.55Ulevostinag
CAS :<p>Ulevostinag (MK-1454) is a STING agonist.</p>Formule :C20H22F2N10O9P2S2Couleur et forme :SolidMasse moléculaire :710.52TLR8 agonist 8
CAS :<p>TLR8 agonist8 (Compound II-72) is an agonist of Toll-like receptor 8 (TLR8) with an EC50 of 0.25-1 μM. It demonstrates stability in both human and mouse plasma and induces the secretion of the cytokine TNFα with an EC50 of less than 1 μM. In the MC38-HER2 xenograft mouse model, TLR8 agonist8 exhibits antitumor activity, achieving a tumor growth inhibition (TGI) rate of 89%.</p>Formule :C53H63N11O10Couleur et forme :SolidMasse moléculaire :1014.14Cryogenine
CAS :<p>Cryogenine, from H. salicifolia, is an anti-inflammatory alkaloid, blocks prostaglandin synthetase, and alleviates rat arthritis.</p>Formule :C26H29NO5Couleur et forme :SolidMasse moléculaire :435.5224-Methylenecholesterol
CAS :<p>24-Methylenecholesterol (24 Methylenecholesterol) is a natural marine sterol, which stimulates cholesterol acyl transferase (ACAT) in human macrophages.</p>Formule :C28H46ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :398.66MitoP
CAS :<p>MitoP forms from H2O2 and MitoB, indicating mitochondria's H2O2 levels when measured by LC-MS/MS.</p>Formule :C25H22BrOPCouleur et forme :SolidMasse moléculaire :449.32Gliotoxin
CAS :<p>Gliotoxin, a mycotoxin, inhibits Wnt pathway, causing apoptosis in mutated colorectal cancer cells and blocks NF-κB by preserving IκB.</p>Formule :C13H14N2O4S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :326.39PROTAC IRAK4 degrader-5
CAS :<p>PROTAC IRAK4 degrader-5 is a Cereblon-based IRAK4 degrader.</p>Formule :C41H40F3N11O9Couleur et forme :SolidMasse moléculaire :887.834Ezeprogind
CAS :<p>Ezeprogind, TLR9 inhibitor for Alzheimer's. Affordable Excellence: Reliable Quality You Can Trust</p>Formule :C25H44N6Degré de pureté :99.28%Couleur et forme :SolidMasse moléculaire :428.66JPE-1375
CAS :<p>JPE-1375: a C5aR1 antagonist, blocks leukocyte mobilization (EC50=6.9 µM), lowers TNF in mice (EC50=4.5 µM), useful for autoimmune/inflammation research.</p>Formule :C49H63FN10O9Couleur et forme :SolidMasse moléculaire :955.08CLIP (86-100)
CAS :<p>Amino acids 86-100 of CLIP, replaced by DM to allow MHC class II to present foreign peptides, triggering immune response.</p>Formule :C72H128N20O19S3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1674.1CAY10512
CAS :<p>CAY10512, a resveratrol analog, is 100x more potent, inhibiting NF-κB with an IC50 of 0.15 μM versus resveratrol's 20 μM.</p>Formule :C15H13FOCouleur et forme :SolidMasse moléculaire :228.266Suc-Tyr-Val-Ala-Asp-pNA
CAS :<p>Suc-YVAD-pNA, a chromogenic caspase-1 substrate.</p>Formule :C31H38N6O12Couleur et forme :SolidMasse moléculaire :686.675FM101
<p>FM101 is a humanized monoclonal anti-IL6 antibody, suitable for use in asthma-related research.</p>Couleur et forme :Odour LiquidBenz-AP
CAS :<p>Benz-AP: potent photosensitizer, creates singlet oxygen, more toxic in low hCES2 cancer cells, generates ROS via TPE to kill tumors.</p>Formule :C20H13NO2Couleur et forme :SolidMasse moléculaire :299.32Dalutrafusp alfa
CAS :<p>Dalutrafusp alfa (AGEN-1423; GS-1423) is a bifunctional antibody targeting CD73 and TGF-β, components of the immunosuppressive pathway [1].</p>Couleur et forme :LiquidPrezalumab
CAS :<p>Prezalumab (AMG 557) is a human IgG2 monoclonal antibody against ICOSL and BAFF.</p>Degré de pureté :> 95%Couleur et forme :LiquidMasse moléculaire :145.42 kDa5-LOX/NO-IN-1
<p>5-LOX/NO-IN-1 (Compound 7e) is a dual inhibitor of 5-LOX and nitric oxide release. It exhibits an IC50 value of 2.833 μM for 5-LOX and demonstrates anti-inflammatory properties.</p>Formule :C22H18N6O4Couleur et forme :SolidMasse moléculaire :430.42Mavrostobart
<p>Mavrostobart is a humanized IgG4κ antibody targeting NT5E, with HumanIgG4(S228P) kappa as its corresponding isotype control.</p>Couleur et forme :Odour LiquidNP3-146
CAS :<p>NP3-146 (NLRP3-IN-5) is an inflammasome NLRP3 inhibitor with potential anti-inflammatory activity for the study of autoimmune diseases.</p>Formule :C20H27ClN2O5SDegré de pureté :99.21%Couleur et forme :SolidMasse moléculaire :442.96Vemircopan
CAS :<p>Vemircopan is a complement factor D inhibitor.</p>Formule :C29H28BrN7O3Couleur et forme :SolidMasse moléculaire :602.493Topramezone
CAS :<p>Topramezone is a 4-HPPD inhibitor herbicide for post-emergence weed control in corn.</p>Formule :C16H17N3O5SCouleur et forme :SolidMasse moléculaire :363.39WAY-605471
CAS :<p>WAY-605471 is a AHR antagonist with IC50 of 0.5 - 1 μM.</p>Formule :C14H15NO3S2Degré de pureté :99.62%Couleur et forme :SolidMasse moléculaire :309.4TLR4-IN-C34-C2-amide-C6-OH
<p>TLR4-IN-C34-C2-amide-C6-OH: a linker with TLR4-IN-C34 that curbs TLR4 and inflammation in mice.</p>Formule :C25H42N2O11Couleur et forme :SolidMasse moléculaire :546.613D-Monophosphoryl Lipid (12,16) free acid
CAS :<p>3D-Monophosphoryl Lipid (12,16) (3D-MPL (12,16)) free acid is a TLR agonist that serves as a vaccine adjuvant to boost the immunogenicity of vaccines.</p>Formule :C96H181N2O21PCouleur et forme :SolidMasse moléculaire :1730.44Mifamurtide TFA
<p>Mifamurtide TFA: muramyl dipeptide analog, boosts immunity, activates macrophages/monocytes, potential osteosarcoma research.</p>Formule :C61H110F3N6O21PCouleur et forme :SolidMasse moléculaire :1351.52Dazostinag
CAS :<p>Dazostinag (TAK-676) is a STING agonist with anti-cancer properties, used in making ADCs.</p>Formule :C21H22F2N8O10P2S2Couleur et forme :SolidMasse moléculaire :710.52Chitoheptaose heptahydrochloride
CAS :<p>Chitoheptaose heptahydrochloride, a chitosan derivative, enhances wheat growth and photosynthesis, with health-protective traits.</p>Formule :C42H80ClN7O29Couleur et forme :SolidMasse moléculaire :1182.57Balekafusp alfa
CAS :<p>Balekafusp alfa is a human IgG1κ antibody targeting IL-2, known for its antitumor properties.</p>Couleur et forme :Liquid(±)19(20)-EDP Ethanolamide
CAS :<p>(±)19(20)-EDP ethanolamide is an ω-3 endocannabinoid epoxide and cannabinoid (CB) receptor agonist (EC50s = 108 and 280 nM for CB1 and CB2, respectively).</p>Formule :C24H37NO3Couleur et forme :SolidMasse moléculaire :387.564Cugrastomig
<p>Cugrastomig is a chimeric antibody of human and humanized IgG1κ-[scFv-heavy -κ]2 type, targeting PDCD1/LAG3.</p>Couleur et forme :Odour Liquid(±)-Phrymarolin II
CAS :<p>(±)-Phrymarolin II is a promising class of inhibitors that targets the tobacco mosaic virus, representing a novel approach in plant virus suppression.</p>Formule :C23H22O10Couleur et forme :SolidMasse moléculaire :458.419Porphyra 334
CAS :<p>Porphyra 334 is a mycosporine-like amino acid.</p>Formule :C14H22N2O8Couleur et forme :SolidMasse moléculaire :346.336Amphimedine
CAS :<p>Amphimedine is a Pyridoacridine Marine Alkaloid.</p>Formule :C19H11N3O2Couleur et forme :SolidMasse moléculaire :313.31Human Immunoglobulin M
<p>Human Immunoglobulin M (IgM) is an antibody secreted by the adaptive immune system in response to foreign antigens. It is a primary type of immunoglobulin released into circulation during the early stages of the primary antibody response. Human Immunoglobulin M forms a pentamer comprising five IgG equivalents, with 10 Fab fragments, allowing for 10 antigen binding sites. Additionally, Human Immunoglobulin M acts as a complement (complement) activator.</p>Couleur et forme :Odour SolidMitoquinol
CAS :<p>Mitoquinol is a mitochondria-targeted antioxidant used in the study of cardiovascular disease by modulating the mitochondrial antioxidant defense system.</p>Formule :C38H49O7PSDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :680.83RDR 02308
CAS :<p>RDR 02308 is a TLR4-MyD88 binding inhibitor that inhibits full-length β-lactamase [1] .</p>Formule :C19H15N3O3Couleur et forme :SolidMasse moléculaire :333.34Damnacanthol
<p>Damnacanthol is a useful organic compound for research related to life sciences and the catalog number is T131609.</p>Formule :C16H12O5Couleur et forme :SolidMasse moléculaire :284.267ADU-S100 disodium salt
CAS :<p>ADU-S100 (MIW815) disodium salt is an activator of stimulator of interferon genes (STING).</p>Formule :C20H22N10Na2O10P2S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :734.51POT-4 acetate
<p>POT-4 acetate inhibits Complement C3 activation. POT-4 acetate can be used for studies about age-related macular degeneration.</p>Formule :C74H106N22O20S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1687.9Anti-IL11RA Antibody (X209)
<p>Anti-IL11RA Antibody (X209) is a human-derived IgG4, κ type antibody inhibitor targeting human IL-11RA.</p>Couleur et forme :Odour LiquidNOD2 agonist 2
<p>NOD2 agonist 2 (compound 23) enhances antigen presentation in murine bone marrow-derived dendritic cells (BMDCs), highlighting its potential as a vaccine adjuvant.</p>Formule :C46H65N3O10Couleur et forme :SolidMasse moléculaire :820.02Alcestobart
<p>Alcestobart is a humanized IgG4κ monoclonal antibody targeting LAG3, with HumanIgG4(S228P) kappa serving as its isotype control.</p>Couleur et forme :Odour LiquidEnglumafusp alfa
<p>Englumafusp alfa (CD19-4-1BBL; RO7227166) is a fusion protein combining a CD19-specific antibody domain with trimerized extracellular domains of human 4-1BBL,</p>Couleur et forme :Odour LiquidNLRP3-IN-50
<p>NLRP3-IN-50 (compound SN3-1) is a potential inhibitor of NLRP3, offering therapeutic promise for inflammatory diseases.</p>Formule :C23H22Cl2N2O4S2Couleur et forme :SolidMasse moléculaire :525.47PROTAC IRAK4 ligand-4
CAS :<p>PROTAC IRAK4 ligand-4, a Ligand for Target Protein for PROTAC (Ligand for Target Protein for PROTAC), exhibits anti-tumor activity and is utilized in synthesizing PROTAC IRAK4 degrader-12. This compound serves as a targeted ligand with specific applications in the development of cancer therapeutics.</p>Formule :C24H26F2N6O3Couleur et forme :SolidMasse moléculaire :484.5hSTING activator-1
<p>hSTING activator-1 (Compound 68) is a STING agonist capable of effectively activating various human STING variants (R232, H232, HAQ), with EC50 values of 56 nM, 89 nM, and 51 nM, respectively. This compound activates the type I interferon pathway by directly binding to the STING protein and stabilizing its conformation, which leads to downstream IRF3 phosphorylation and cytokine release. hSTING activator-1 also demonstrates potential in cancer research by inhibiting fibrosarcoma tumor growth.</p>Couleur et forme :Odour SolidRedaporfin
CAS :<p>Redaporfin (F-2BMet, LUZ-11) is a PDT cancer photosensitizer; 83% of mice had tumor regression with 1.5 mg/kg and 74 J/cm² light.</p>Formule :C48H38F8N8O8S4Couleur et forme :SolidMasse moléculaire :1135.11Dibenzothiophene
CAS :<p>Dibenzothiophene, a sulfur PAH in petroleum, has 3 rings and keratolytic properties.</p>Formule :C12H8SDegré de pureté :99.82%Couleur et forme :Yellow To Green SolidMasse moléculaire :184.26NLRP3-IN-73
<p>NLRP3-IN-73 (W16) is an orally bioavailable inhibitor that disrupts the assembly of the NLRP3 inflammasome, exhibiting an IC50 value of 0.18 μM for the NLRP3/IL-1β pathway.</p>Couleur et forme :Odour SolidBiotin-labeled ODN TTAGGG sodium
<p>Biotin-labeled ODN TTAGGG (sodium) is an inhibitory oligonucleotide (ODN) that functions as an antagonist to TLR9, AIM2, and cGAS.</p>Couleur et forme :Odour SolidPerfluorohexane
CAS :<p>Perfluorohexane (AF-0150) is a perfluorocarbon (PFC)-based microbubble formulation for ultrasound contrast and is developmentally toxic.</p>Formule :C6F14Degré de pureté :98%Couleur et forme :Colourless LiquidMasse moléculaire :338.04TH023
<p>TH023 is an inhibitor of the TLR4 signaling pathway, specifically targeting the formation of TLR4 homodimers. In HEK-Blue hTLR4 cells, TH023 suppresses the secretion of embryonic alkaline phosphatase with an IC50 of 0.354 μM and inhibits NO expression in RAW264.7 cells, with an IC50 of 1.61 μM. Additionally, TH023 inhibits the activation of NF-κB and reduces the nuclear translocation of NF-κB p65. The compound demonstrates anti-inflammatory effects in a mouse model of LPS-induced acute sepsis and improves lung injury in mice.</p>Formule :C22H21ClF2N4OCouleur et forme :SolidMasse moléculaire :430.88GHN105
<p>GHN105 is an orally active STING inhibitor that suppresses STING-dependent IFN-β secretion in THP-1 human monocytes with an IC50 of 4.4 μM. In mice, GHN105 reduces serum levels of IFN-β, IL-6, and CXCL10, and alleviates colitis in a DSS-induced acute colitis mouse model. Additionally, GHN105 demonstrates favorable pharmacokinetic properties in mice, with an oral bioavailability of 43% and a half-life of 1.1 hours.</p>Formule :C41H56N2O14Couleur et forme :SolidMasse moléculaire :800.89CD19 CAR mRNA
<p>CD19 CAR mRNA expresses a protein for use in CAR-CD19 T cell therapy, targeting B cell antigen for cancer treatment.</p>Couleur et forme :SolidPrifelone
CAS :<p>Prifelone (R 830) is a non-steroidal anti-inflammatory compound with antioxidant activity.</p>Formule :C19H24O2SDegré de pureté :99.8%Couleur et forme :SolidMasse moléculaire :316.462'2'-cGAMP (sodium salt)
CAS :<p>2'2'-cGAMP, a synthetic CDN, binds STING in the immune response, inducing IFN-β; binds weaker than 2'3'-cGAMP but stronger than other CDNs.</p>Formule :C20H24N10O13P2Couleur et forme :SolidMasse moléculaire :674.417RH-EDA
<p>RH-EDA, a rhodamine-based turn-on fluorescent probe, detects hydroxyl radicals ([OH]) in living systems.</p>Formule :C28H25N3O4Couleur et forme :SolidMasse moléculaire :467.52Bermoprofen
CAS :<p>Bermoprofen (AD-1590) is an anti-inflammatory compound with anti-inflammatory and analgesic activity used in the study of gastric ulcers.</p>Formule :C18H16O4Degré de pureté :98.72% - 99.28%Couleur et forme :SolidMasse moléculaire :296.32STING agonist-31
CAS :<p>STING agonist-31, a potent STING agonist, exhibits EC50 values of 0.24 μM and 39.51 μM for human STING (h-STING) and murine STING (m-STING), respectively,</p>Formule :C43H51N15O6Couleur et forme :SolidMasse moléculaire :873.96MC4762
<p>MC4762 is an inhibitor of NOX2 and MAOB, with IC50 values of 0.155 μM and 0.182 μM, respectively. It exhibits anti-inflammatory properties by suppressing the production of ROS and downregulating the expression of pro-inflammatory cytokines such as iNOS, IL-1β, and IL-6.</p>Couleur et forme :Odour SolidInflexuside B
CAS :<p>Inflexuside B, an abietane diterpenoid derived from the aerial parts of Isodon inflexus, effectively inhibits lipopolysaccharide (LPS)-activated NO Synthase in</p>Formule :C35H48O11Couleur et forme :SolidMasse moléculaire :644.75MS7829
<p>MS7829 is a first-class DUBTAC targeting cGAS, a critical component in the cGAS-STING pathway.</p>Couleur et forme :Odour Solidα-Guanidinoglutaric Acid
CAS :<p>α-Guanidinoglutaric Acid is found in cobalt-induced epileptogenic focus tissue in the cerebral cortex of cats.</p>Formule :C6H11N3O4Degré de pureté :99.73%Couleur et forme :SolidMasse moléculaire :189.17STING ligand-2
CAS :<p>STING ligand-2 serves as a ligand for STING and can be utilized as the target protein ligand in the synthesis of the PROTAC degrader STING-IN-10.</p>Formule :C13H12N2O5Couleur et forme :SolidMasse moléculaire :276.25C5aR2 agonist P32 acetate
<p>C5aR2 agonist P32 acetate (Ac-RHYPYWR-OH), a selective agonist for C5aR2, has been shown to induce various immunomodulatory activities both in vitro and in vivo. It modulates cell signaling via the downregulation of C5aR1-mediated pathways and can also function independently of C5aR1.</p>Formule :C54H70N16O11·xC2H4O2Couleur et forme :SolidMasse moléculaire :1119.23 (free base)IL-6-IN-1
<p>IL-6-IN-1 (Compound 22) inhibits the release of IL-6 with an IC50 of 1.065 μM and demonstrates anti-inflammatory activity in LPS-induced acute lung injury in mice.</p>Formule :C16H12N2OSCouleur et forme :SolidMasse moléculaire :280.34PSMA-ALB-56
CAS :<p>PSMA-ALB-56: radioactive, PSMA-targeted ligand, antitumor, combines glutamic urea, DOTA, albumin, with iodophenyl or tolyl fragments.</p>Formule :C66H95N11O18Couleur et forme :SolidMasse moléculaire :1330.52RS 09 TFA
<p>RS 09 TFA is a TLR4 agonist and LPS peptide analogue, promotes NF-κB nuclear translocation, induces inflammatory cytokine secretion in RAW264.7 macrophages.</p>Formule :C33H50F3N9O11Degré de pureté :99.78%Couleur et forme :SolidMasse moléculaire :805.8Antifungal agent 123
<p>Antifungalagent 123 (Compound 4b) demonstrates strong affinity for the oxidoreductase of Staphylococcus aureus or membrane proteins of Candida albicans, exhibiting both antibacterial and antifungal properties. Additionally, it is capable of scavenging free radicals, showcasing antioxidant effects. Antifungalagent 123 also inhibits the TLR signaling pathway and possesses anti-inflammatory activity.</p>Formule :C21H20N4O3Couleur et forme :SolidMasse moléculaire :376.4094-hydroperoxy 2-Nonenal
CAS :<p>4-HNE, a marker of oxidative stress, arises from oxidized ω-6 fats like linoleic acid and shows cytotoxic and genotoxic effects.</p>Formule :C9H16O3Couleur et forme :SolidMasse moléculaire :172.2244'-hydroxy Flurbiprofen
CAS :<p>4'-hydroxy Flurbiprofen can be used in related research in the field of life sciences. Its product number is T35722 and CAS number is 52807-12-2.</p>Formule :C15H13FO3Couleur et forme :SolidMasse moléculaire :260.264BMS-986148
<p>BMS-986148 is a CHO-expressed humanized antibody-drug coupling targeting mesothelin-expressing cells for cytotoxic load delivery.</p>Degré de pureté :98.1% (SDS-PAGE); 99% (SEC-HPLC) - 98.1% (SDS-PAGE); 99% (SEC-HPLC)Couleur et forme :Odour LiquidNG-Hydroxy-L-arginine acetate
CAS :<p>NG-Hydroxy-L-arginine acetate (NOHA acetate) acts as a crucial physiological inhibitor of arginase, playing a vital role in the conversion of arginine to nitric oxide and citrulline via nitric oxide synthase.</p>Formule :C6H14N4O3xC2H4O2Couleur et forme :SolidMasse moléculaire :190.20（free base）Antitumor agent-188
<p>Antitumor agent-188 (compound C6) exhibits α-glucosidase inhibitory activity and anticancer properties. It induces excessive ROS production, thereby triggering oxidative stress.</p>Formule :C25H44FN3O7Couleur et forme :SolidMasse moléculaire :517.63CHBO4
CAS :<p>CHBO4 is an hMAO-B inhibitor that is potent, reversible, competitive and selective.The IC50 value of CHBO4 against hMAO-B in the CHBO assay was 0.031 μM, and</p>Formule :C15H10BrFODegré de pureté :98.14%Couleur et forme :SolidMasse moléculaire :305.14Aβ-IN-6
<p>Aβ-IN-6 is an orally active compound exhibiting anti-inflammatory, antioxidant, and anti-oligomeric activities, with significant implications for Alzheimer's</p>Formule :C28H31N3O4Couleur et forme :SolidMasse moléculaire :473.56Multinoside A
CAS :<p>Multinoside A is a useful organic compound for research related to life sciences. The catalog number is T124593 and the CAS number is 59262-54-3.</p>Formule :C27H30O16Couleur et forme :SolidMasse moléculaire :610.5214-Methylamino antipyrine hydrochloride
CAS :<p>4-Methylamino antipyrine hydrochloride is an active metabolite of Metamizole.</p>Formule :C12H16ClN3ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :253.73PSMA-D5
CAS :<p>PSMA-D5 exhibits a binding affinity for PSMA with a Ki of 0.21 nM and becomes useful for PSMA tracing following radiolabeling. When marked with [68Ga], PSMA-D5 contains a DOTA chelator, facilitating the convenient labeling with therapeutic radionuclides such as 177Lu and 225Ac. Additionally, [68Ga]-labeled PSMA-D5 demonstrates exceptional pharmacokinetic properties and significant tumor uptake in 22Rv1 tumors. This compound can be employed in the synthesis and research of radiolabeled conjugates (RDC).</p>Formule :C57H80N12O24Couleur et forme :SolidMasse moléculaire :1317.31Flunixin
CAS :<p>Flunixin is a nonsteroidal anti-inflammatory drug (NSAID), antipyretic, and analgesic used in pigs, horses, and cattle.</p>Formule :C14H11F3N2O2Couleur et forme :SolidMasse moléculaire :296.24Axinelline A
CAS :<p>Axinelline A: COX inhibitor, IC50 of 2.22 μM (COX-2) & 8.89 μM (COX-1), anti-inflammatory.</p>Formule :C12H15NO6Couleur et forme :SolidMasse moléculaire :269.25Biotin-labeled Agatolimod sodium
<p>Biotin-labeled Agatolimod (sodium), a class B CpG ODN (oligodeoxynucleotide) and TLR9 agonist, facilitates the assessment of cellular uptake and localization of</p>Couleur et forme :Odour SolidQKY-613
CAS :<p>QKY-613 is a prodrug designed to enhance immune surveillance by targeting nucleic acid modification pathways. It selectively facilitates the incorporation of 6mdA (N6-methyl-deoxyadenosine) into viral DNA, boosting the DNA's phase separation potential and subsequently increasing cGAS activation levels to strengthen host immune surveillance. In mouse models of viral infection, QKY-613 significantly reduced mortality in aged mice. This compound holds promise for studying immune surveillance mechanisms based on nucleic acid modifications.</p>Formule :C27H31N6O7PCouleur et forme :SolidMasse moléculaire :582.55Septeremophilane E
<p>Septeremophilane E, from Septoria rudbeckiae fungus, inhibits NO production.</p>Formule :C21H26O5Couleur et forme :SolidMasse moléculaire :358.43Pirenoxine
CAS :<p>Pirenoxine is an agent with anti-cataractogenesis activity by interacting with calcium ions or selenite which could lead to the formation of lens cataract.</p>Formule :C16H8N2O5Couleur et forme :SolidMasse moléculaire :308.25OVA Peptide(257-264)
CAS :<p>OVA Peptide(257-264) is an ovalbumin octamer Peptide expressed by class I MHC molecule h-2kb.</p>Formule :C45H74N10O13Degré de pureté :99.53%Couleur et forme :SolidMasse moléculaire :963.13Anti-inflammatory agent 93
<p>Compound 2g (Anti-inflammatory agent 93) is an active compound that exhibits analgesic activity.</p>Formule :C27H17Cl2N3O2Couleur et forme :SolidMasse moléculaire :486.35AHR antagonist 5 free base
CAS :<p>AHR antagonist 5 free base is an orally active AHR antagonist and exhibits anticancer activity.Cost-effective and quality-assured.</p>Formule :C25H24FN7Degré de pureté :99.88%Couleur et forme :SolidMasse moléculaire :441.5Cbl-b-IN-28
<p>Cbl-b-IN-28 (Compound B2) is an orally active Cbl-b inhibitor. It enhances the function of immune cells by promoting the secretion of cytokines like IL-2 and modulating the phosphorylation levels of key proteins in the T cell receptor signaling pathway. Cbl-b-IN-28 is applicable in cancer immunology research.</p>Couleur et forme :Odour SolidHS-243
CAS :<p>HS-243 is an inhibitor of IRAK-4 and IRAK-1 with IC50s of 20 and 24 nM. HS-243 shows anti-inflammatory and anticancer activity.</p>Formule :C17H16N4O3Degré de pureté :98.62%Couleur et forme :SolidMasse moléculaire :324.33CU-115
CAS :<p>CU-115 is a selective and potent TLR8 antagonist with IC50 of 1.04 µM and =>50 µM for TLR8 and TLR7, respectively.</p>Formule :C21H11F7INO2Degré de pureté :99.96%Couleur et forme :SolidMasse moléculaire :569.21Pelgifatamab
CAS :<p>Pelgifatamab (BAY-2315497) is a prostate-specific membrane antigen (PSMA) antibody with potential anticancer activity that can be used to study prostate cancer.</p>Degré de pureté :97.9% (SDS-PAGE); 95.1% (SEC-HPLC) - 97.9% (SDS-PAGE); 95.1% (SEC-HPLC)Couleur et forme :LiquiddiABZI STING agonist-1 trihydrochloride
CAS :<p>diABZI STING agonist-1 (trihydrochloride) is stimulator of interferon genes (STING) receptor agonist.</p>Formule :C42H54Cl3N13O7Degré de pureté :95.33% - 99.55%Couleur et forme :SolidMasse moléculaire :959.32Antiviral agent 61
<p>Antiviralagent 61 (compound Z40) serves as an effective antiviral agent with activity against Tomato Spotted Wilt Virus (TSWV), exhibiting an EC50 value of 252 µg/mL. It increases the RNA expression of Ndufb9, COX6B, 7.1.2.2, E, COX5B, Ndufs4, and SDHB, while reducing the expression of Ndufb7, Ndufa5, and G.</p>Formule :C22H23N5O4SCouleur et forme :SolidMasse moléculaire :453.51Pepinh-MYD
CAS :<p>Pepinh-MYD, a MyD88 inhibitor, incorporates both a domain sequence from MyD88 TIR and a protein transduction sequence to facilitate cell membrane penetration. This compound disrupts MyD88-mediated TLR signaling pathways, effectively inhibiting associated immune responses. Its design is particularly useful for investigating MyD88's function in viral infections.</p>Formule :C151H248N50O35S2Couleur et forme :SolidMasse moléculaire :3388.03PSB-12379 ditriethylamine salt
<p>PSB-12379 ditriethylamine salt, a nucleotide analogue, is a potent Ecto-5'-Nucleotidase (CD73) inhibitor with Kis of 9.03 nM (rat) and 2.21 nM (human).</p>Formule :C30H53N7O9P2Degré de pureté :98.26% - 99.44%Couleur et forme :SolidMasse moléculaire :717.73Vadastuximab
<p>Vadastuximab (Anti-Human CD33 Recombinant Antibody) is a humanized anti-CD33 monoclonal antibody for the study of acute myeloid leukemia (AML).</p>Degré de pureté :98.5% (SDS-PAGE); 97.3% (SEC-HPLC) - 98.5% (SDS-PAGE); 97.3% (SEC-HPLC)Couleur et forme :LiquidMasse moléculaire :145.5 kDaiNOs-IN-6
<p>iNOs-IN-6 is an anti-inflammatory agent known for inhibiting the expression of NF-κB, iNOS, and MAPK with an IC50 ranging from 0.2 to 0.62 μM. Additionally, it decreases the levels of pro-inflammatory mediators, such as IL-6, TNF-α, and IL-1β, with an IC50 ranging from 0.4 to 0.69 μM.</p>Couleur et forme :Odour SolidTPNA10168
CAS :<p>Compound Fr13590, with CAS No. 957942-34-6, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound Fr13590 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.</p>Formule :C9H9ClO2S2Couleur et forme :SolidMasse moléculaire :248.75TD139
CAS :<p>TD139 is an inhaled small molecule inhibitor of galectin-3 (Gal-3) with potential anti-fibrotic activity. Cost-effective and quality-assured.</p>Formule :C28H30F2N6O8SDegré de pureté :97.82% - 99.66%Couleur et forme :SolidMasse moléculaire :648.64IL-17-IN-3
<p>IL-17-IN-3 (compound 11) is an IL-17A inhibitor with an IC50 value of 35 nM. In a rat tolerance study, it showed no adverse reactions when administered at doses up to 300 mg/kg/day for four consecutive days.</p>Formule :C22H25F6N5O3SCouleur et forme :SolidMasse moléculaire :553.521CRX-526
CAS :<p>CRX-526, a TLR4 antagonist, protects against advanced diabetic nephropathy.</p>Formule :C69H127N2O19PDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :1319.72IACS-8803 disodium
CAS :<p>IACS-8803 Disodium, a potent cyclic dinucleotide STING agonist, exhibits strong systemic antitumor efficacy [1].</p>Formule :C20H21FN10Na2O9P2S2Couleur et forme :SolidMasse moléculaire :736.50SN50
CAS :<p>SN50 is a cell-permeable inhibitor of NF-κB nuclear translocation that protects against ventilator-induced acute lung injury in rats.</p>Formule :C129H230N36O29SDegré de pureté :99.91%Couleur et forme :SolidMasse moléculaire :2781.5Guaiacol-d3
CAS :<p>Guaiacol-d3 is a deuterated form of Guaiacol, which is a phenolic compound known for its ability to inhibit COX-2 expression and NF-κB activation in response to LPS stimulation, exhibiting anti-inflammatory properties.</p>Formule :C7H8O2Couleur et forme :SolidMasse moléculaire :127.16M-TriDAP TFA
<p>M-TriDAP (N-Acetylmuramyl-L-Ala-γ-D-Glu-meso-diaminopimelic acid) TFA is a bioactive peptide that functions as an agonist for NOD1/2.</p>Formule :C26H43N5O15·xC2HF3O2Pegaldesleukin
CAS :<p>Pegaldesleukin, a PEG-IL2 conjugate, exhibits antiviral properties, potentially slowing HIV progression, preserving immune function.</p>Couleur et forme :LiquidIcatolimab
<p>Icatolimab (JS-004) is a humanized antibody targeting BTLA/CD272 for the study of lymphomas and solid tumors.</p>Degré de pureté :98.7% (SDS-PAGE); 95.6% (SEC-HPLC) - 98.7% (SDS-PAGE); 95.6% (SEC-HPLC)Couleur et forme :LiquidMasse moléculaire :145.5 kDaCarboxy-PTIO
CAS :<p>Carboxy-PTIO rapidly scavenges NO, forming NO2, key in preventing hypotension and shock in rats.</p>Formule :C14H17N2O4Couleur et forme :SolidMasse moléculaire :277.3Fentiazac
CAS :<p>Fentiazac (BR-700) is an oral NSAID for pain, inflammation, fever, studied for arthritis and tendonitis.</p>Formule :C17H12ClNO2SDegré de pureté :99.83%Couleur et forme :SolidMasse moléculaire :329.8β-Interleukin II (44-56)
<p>β-Interleukin II is a peptide with the sequence NH2-ILE-LEU-ASN-GLY-ILE-ASN-ASN-TYR-LYS-ASN-PRO-LYS-LEU-COOH.</p>Formule :C68H113N19O19Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1500.74CIB-1476
<p>CIB-1476, a caspase-1 inhibitor, effectively reduces joint swelling in mouse models of arthritis and demonstrates lasting anti-inflammatory effects. This compound achieves its benefits by blocking IL-1β production, NF-κB activation, and GSDMD-mediated pyroptosis, all of which are triggered by the NLRP3 inflammasome.</p>Formule :C28H28N2O6SCouleur et forme :SolidMasse moléculaire :520.6Somantadine
CAS :<p>Somantadine has antiviral activities and can be used for research on preventing and treating coronavirus-related diseases.</p>Formule :C14H25NDegré de pureté :99.9%Couleur et forme :SolidMasse moléculaire :207.35FITC-labeled ODN 2395 sodium
<p>FITC-labeled ODN 2395 (sodium), a class C oligodeoxynucleotide and TLR9 agonist, facilitates the assessment of CpG ODN cellular uptake and localization through</p>Couleur et forme :Odour SolidPSMα3
CAS :<p>PSMα3 is a peptide compound that can be utilized to induce tolerance in dendritic cells (DCs) for DC vaccination strategies.</p>Formule :C128H192N28O30SCouleur et forme :SolidMasse moléculaire :2635.17SN50 TFA
<p>SN50 TFA is an inhibitor of NF-κB and attenuates alveolar hypercoagulation and fibrinolysis inhibition. SN50 TFA can be used in studies about ARDS.</p>Formule :C129H230N36O29S·XCF3COOHCouleur et forme :SolidMasse moléculaire :2781.5 (free base)TBK1/IKKε-IN-6
CAS :<p>TBK1/IKKε-IN-6 (example 110) is a potent inhibitor of TBK1 and IKKε, with IC50 values of less than 100 nM for both enzymes.</p>Formule :C31H36F2N8O4Couleur et forme :SolidMasse moléculaire :622.678NLRP3-IN-15
CAS :<p>NLRP3-IN-15: potent, selective NLRP3 inflammasome inhibitor; IC50 0.114 μM for IL-1β; for inflammation research.</p>Formule :C22H19NO4Couleur et forme :SolidMasse moléculaire :361.39Maresin 2
CAS :<p>Maresin 2 (3R,14S-diHDHA) is a specialized pro-ablative lipid mediator with anti-inflammatory and analgesic activity that promotes mucosal repair.</p>Formule :C22H32O4Couleur et forme :SolidMasse moléculaire :360.496'-O-Galloylsalidroside
CAS :<p>6'-O-Galloylsalidroside has antiviral activity and inhibits HIV.</p>Formule :C21H24O11Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :452.41CQ-16
CAS :<p>CQ-16 is an orally active small molecule drug conjugate (SMDC) that targets prostate-specific membrane antigen (PSMA). It exhibits high selectivity in its antiproliferative activity between PSMA-positive and PSMA-negative prostate cells. Additionally, CQ-16 possesses PARP inhibitory activity (IC50=1 nM).</p>Formule :C40H47FN8O12Couleur et forme :SolidMasse moléculaire :850.85Anticancer agent 15
CAS :<p>Anticancer agent 15 raises ROS, causing necroptosis in melanoma cells.</p>Formule :C35H40Cl2N2O5Couleur et forme :SolidMasse moléculaire :639.61Siplizumab
CAS :<p>Siplizumab (MEDI-507), an IgG1 antibody targeting CD2, depletes T cells, may treat psoriasis.</p>Degré de pureté :100% (SEC-HPLC) - > 95%Couleur et forme :LiquidMasse moléculaire :147.24 kDaDithianon
CAS :<p>Dithianon: broad-spectrum anthraquinone fungicide; sticks to leaves/fruits; controls various fungi in some produce.</p>Formule :C14H4N2O2S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :296.32R-HP210
<p>R-HP210 blocks LPS-triggered IL-1β, IL-6, COX-2 gene transcription and has a 3.80 μM IC50 for NF-κB inhibition without activating GCs.</p>Formule :C22H19N3O2S2Couleur et forme :SolidMasse moléculaire :421.54diABZI-V/C-DBCO
<p>Compound 3 (diABZI-V/C-DBCO) functions as an efficient STING agonist. This compound acts by releasing diABZI-amine under the action of cathepsin B to activate STING, thereby inducing the production of interferon and other immune-activating molecules, which enhances the immune system's response to tumors. In THP1-Dual cells, the EC50 values for STING activation by diABZI-V/C-DBCO and diABZI-amine are 1.47 nM and 0.144 nM, respectively, and in primary mouse splenic cells, the EC50 values are 7.7 µM and 0.17 µM, respectively. diABZI-V/C-DBCO is useful for research in the field of cancer immunotherapy.</p>Formule :C78H89N19O13Couleur et forme :SolidMasse moléculaire :1500.66Hispaglabridin A
CAS :<p>Hispaglabridin A, an effective antioxidant, inhibits lipid peroxidation [1].</p>Formule :C25H28O4Couleur et forme :SolidMasse moléculaire :392.49MEDI-7836
<p>MEDI-7836 is a humanized monoclonal antibody inhibitor that targets the interleukin-13 (interleukin-13 receptor) receptor. It shows potential for research into diseases associated with inflammation.</p>Couleur et forme :Odour LiquidAnti-Human MSLN Antibody (Clone HN1)
<p>Anti-Human MSLN Antibody (Clone HN1) is a humanised monoclonal antibody targeting MSLN (Mesothelin), , blocks the interaction between MSLN and CA125, cancer .</p>Degré de pureté :95%Couleur et forme :Odour LiquidNLRP3-IN-45
<p>NLRP3-IN-45 (D6) serves as an inhibitor specifically targeting the NLRP3 inflammasome, demonstrated through its ability to curb the activity of IL-1β (IC 50 = 41.79 nM). It effectively prevents the activation of the NLRP3 inflammasome while sparing the initial stages of its activation process. Furthermore, NLRP3-IN-45 has been shown to selectively inhibit NLRP3 inflammasome activation in the LPS-induced acute lung injury (ALI) mouse model.</p>Formule :C27H30FNO6Couleur et forme :SolidMasse moléculaire :483.532-Iminobiotin
CAS :<p>2-Iminobiotin inhibits iNOS/nNOS; Ki: 21.8 μM (mouse iNOS), 37.5 μM (rat nNOS).</p>Formule :C10H17N3O2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :243.33Sartorypyrone D
CAS :<p>Sartorypyrone D, from N. fischeri, inhibits NFRD (1.7 μM) and NADH oxidase (3 μM), and fights Gram-positive bacteria.</p>Formule :C26H38O4Couleur et forme :SolidMasse moléculaire :414.586Tri(TLR4-IN-C34-C2-amide-C3-amide-PEG1)-amide-C3-COOH
<p>Tri(TLR4-IN-C34) linker reduces inflammation by inhibiting TLR4 in cells, shown effective in mouse endotoxemia and enterocolitis.</p>Formule :C84H134N10O39Couleur et forme :SolidMasse moléculaire :1908.01Ara-F-NAD+ sodium
<p>Ara-F-NAD+ sodium, an arabino analogue of NAD+, serves as a potent, reversible, and slow-binding inhibitor of the CD38 NADase [1] [2].</p>Formule :C21H25FN7NaO13P2Couleur et forme :SolidMasse moléculaire :687.4Eritoran Tetrasodium
CAS :<p>Eritoran Tetrasodium, a TLR4 receptor antagonist, is used potentially for the treatment of type 2 diabetes.</p>Formule :C66H122N2Na4O19P2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1401.58Eramkafusp Alfa
<p>Eramkafusp alfa is a human IgG1 antibody that targets the murine B lymphocyte antigen CD20, also known as MS4A1 [1].</p>Couleur et forme :Odour LiquidBiotin-labeled ODN 2216 sodium
<p>Biotin-labeled ODN 2216 (sodium) serves as a specific agonist for human TLR9 (toll-like receptor 9), facilitating the assessment of CpG ODN cellular uptake and</p>Couleur et forme :Odour SolidSTING agonist-25
CAS :<p>STING agonist-25 is a non-nucleotide that activates STING, enhances immune response, and is active against SARS-CoV strains.</p>Formule :C36H41N13O6Couleur et forme :SolidMasse moléculaire :751.79Nogapendekin alfa inbakicept
CAS :<p>Nogapendekin alfa inbakicept is an IL-15 superagonist that enhances anti-tumor immune responses by activating NK cells and T cells. It is being studied for use in non-muscle invasive bladder cancer (NMIBC).</p>Couleur et forme :Solid(Rac)-γ-Tocopherol
CAS :<p>(Rac)-γ-Tocopherol (DMPBQ) is an isoform of Vitamin E that undergoes conversion to γ-Tocopherol through the action of tocopherol cyclase.</p>Formule :C28H48O2Couleur et forme :SolidMasse moléculaire :416.68Olendalizumab
CAS :<p>Olendalizumab (ALXN1007) is a humanized antibody targeting C5a for research on COVID-19-related inflammation.</p>Couleur et forme :LiquidHNGF6A
CAS :<p>increases glucose stimulated insulin secretion and glucose metabolism</p>Formule :C112H198N34O31S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :2581.11Mesalamine impurity P
CAS :<p>Mesalamine impurity P, a 5-Aminosalicylic acid derivative, is a PPARγ agonist, inhibiting PAK1 and NF-κB.</p>Formule :C13H11NO6SCouleur et forme :SolidMasse moléculaire :309.30TSR-033
CAS :<p>TSR-033 is a human IgG4 antibody with high affinity for LAG-3 (lymphocyte activation gene-3), a co-receptor linked to diminished T cell activity, frequently co-</p>Couleur et forme :LiquidE7766 disodium
CAS :<p>E7766 disodium, a macrocycle-bridged STING agonist, exhibits a binding affinity (Kd) of 40 nM, demonstrating potent pan-genotypic and antitumor effects.</p>Formule :C24H26F2N10Na2O8P2S2Couleur et forme :SolidMasse moléculaire :792.58ABX-IL8
<p>ABX-IL8 is a humanized antibody targeting IL-8, capable of interfering with tube formation in human umbilical vein endothelial cells.</p>Degré de pureté :>95%Couleur et forme :LiquidMasse moléculaire :145.5 kDaSTING-IN-13
<p>STING-IN-13 is a selective STING inhibitor that effectively suppresses downstream signaling of the STING pathway and STING-mediated inflammation. It exhibits low toxicity and is suitable for research related to STING-associated inflammatory and autoimmune diseases.</p>Couleur et forme :Odour SolidWithangulatin A
CAS :<p>Withangulatin A, a COX-2 inhibitor from Physalis angulata, has anti-tumor and anti-inflammatory effects.</p>Formule :C30H38O8Couleur et forme :SolidMasse moléculaire :526.62Phthalazine
CAS :<p>Compound PDK0135, with CAS No. 253-52-1, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound PDK0135 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.</p>Formule :C8H6N2Couleur et forme :Yellow SolidMasse moléculaire :130.14Clazakizumab
CAS :<p>Clazakizumab: monoclonal antibody targeting IL-6, may inhibit COVID-19 cytokine response, researched for PsA and renal rejection.</p>Couleur et forme :LiquidCAY10614
CAS :<p>CAY10614 is a TLR4 antagonist.</p>Formule :C42H78INO2Couleur et forme :SolidMasse moléculaire :755.995Dovanvetmab
CAS :<p>Dovanvetmab (ZTS-00521505) is an IgG1-κ monoclonal antibody that targets feline interleukin 31 (Felcat IL31), primarily produced in Chinese Hamster Ovary (CHO)</p>Couleur et forme :LiquidIMGN-779
<p>IMGN-779 (Anti-CD33 Antibody) is a humanized antibody targeting CD33 with antileukemic activity, which can be used to study leukemia.</p>Degré de pureté :>95%Couleur et forme :Odour LiquidLY-402913
CAS :<p>LY-402913 is a selective multidrug resistance protein (MRP1) inhibitor.</p>Formule :C28H24ClN3O6Degré de pureté :99.73%Couleur et forme :SolidMasse moléculaire :533.96BQ0413
CAS :<p>BQ0413 exhibits high affinity for PSMA, with a dissociation constant (KD) of 89 pM. It demonstrates effective uptake and internalization, with an internalization rate of 44% in PC3-pip cells. After being labeled with [99mTc], BQ0413 can serve as an imaging agent for tumors.</p>Formule :C69H96N12O24SCouleur et forme :SolidMasse moléculaire :1509.63UT-11
<p>UT-11: potent, brain-permeable mPGES-1 inhibitor. IC50: 0.10μM (human SK-N-AS), 2.00μM (murine BV2). Stops PGE2 production.</p>Formule :C17H19Cl2N3O2SCouleur et forme :SolidMasse moléculaire :400.32PSB-12379 disodium
<p>PSB-12379 disodium is a nucleotide analogue acting as a potent inhibitor of Ecto-5'-Nucleotidase (CD73), demonstrating inhibitory constants (Ki) of 9.03 nM in</p>Formule :C18H21N5Na2O9P2Couleur et forme :SolidMasse moléculaire :559.31KD014
<p>KD014 (DX-2400) is a human monoclonal antibody (mAb) that targets MMP14, with a Ki of 0.9 nM. It inhibits TGFβ and SMAD2/3 signaling, increases macrophage count and iNOS expression, and shifts macrophage phenotype towards an antitumor M1-like type. KD014 exhibits antitumor activity in three tumor models (MDA-MB-231, MDA-MB-435, and PC3) and is applicable in breast cancer research.</p>Couleur et forme :Odour Liquid
