Immunologie et Inflammation
Les inhibiteurs en immunologie et inflammation sont des composés qui modulent la réponse immunitaire et les processus inflammatoires. Ces inhibiteurs sont cruciaux pour étudier les mécanismes de la régulation immunitaire, l'auto-immunité et l'inflammation chronique, ainsi que pour développer des traitements pour les maladies inflammatoires, les allergies et les troubles immunitaires. En ciblant des voies clés du système immunitaire, ces inhibiteurs peuvent aider à réduire les réponses immunitaires excessives ou inappropriées. Chez CymitQuimica, nous offrons une large sélection d'inhibiteurs de haute qualité en immunologie et inflammation pour soutenir vos recherches en immunologie, inflammation et développement thérapeutique.
Sous-catégories appartenant à la catégorie "Immunologie et Inflammation"
- RCC(136 produits)
- CXCR(147 produits)
- Paroi cellulaire(5 produits)
- Récepteur IL(113 produits)
- IκB/IKK(61 produits)
- LTR(3 produits)
- MALT(23 produits)
- MRP(6 produits)
- NADPH-oxydase(1 produits)
- NF-κB(445 produits)
- NOD(17 produits)
- NOS(63 produits)
- Nrf2(78 produits)
- PGE Synthase(31 produits)
- ROS(69 produits)
- TGF-beta/Smad(58 produits)
- TLR(66 produits)
- Thioredoxine(12 produits)
- gp120/CD4(4 produits)
Affichez 11 plus de sous-catégories
3035 produits trouvés pour "Immunologie et Inflammation"
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Fudosteine
CAS :<p>Fudosteine is a novel mucoactive agent and a MUC5AC mucin hypersecretion inhibitor.</p>Formule :C6H13NO3SDegré de pureté :99.59%Couleur et forme :Off-White CrystallineMasse moléculaire :179.24Erdosteine
CAS :<p>Erdosteine (RV 144), a mucolytic thiol, modulates mucus and aids expectoration, reduces cough, and protects lungs from smoke damage.</p>Formule :C8H11NO4S2Degré de pureté :99.43% - 99.94%Couleur et forme :White Or Almost White Crystalline PowderMasse moléculaire :249.31(3E,4S)-3-{2-[(1R,4aS,5R,6R,8aS)-6-hydroxy-5-(hydroxymethyl)-5,8a-dimethyl-2-methylidene-decahydronaphthalen-1-yl]ethylidene}-4-hydroxyoxolan-2-one
CAS :Formule :C20H30O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :350.4492S-Nitroso-N-acetyl-DL-penicillamine
CAS :<p>S-Nitroso-N-acetyl-DL-penicillamine (SNAP) acts as a stable inhibitor of platelet aggregation, is a nitric oxide donor and .</p>Formule :C7H12N2O4SDegré de pureté :97.42% - >99.99%Couleur et forme :Green Crystalline SolidMasse moléculaire :220.25GSK3145095
CAS :<p>GSK3145095 is an orally active inhibitor of RIPK1 with IC50 of 5 nM, with potential immunomodulatory activities and antineoplastic.</p>Formule :C20H17F2N5O2Degré de pureté :99.50%Couleur et forme :SolidMasse moléculaire :397.38TBK1/IKKε-IN-2
CAS :<p>TBK1/IKKε-IN-2 is a dual inhibitor of TBK1 and IKKε.</p>Formule :C26H27N5O3Degré de pureté :98.89%Couleur et forme :SolidMasse moléculaire :457.524-Imidazoleacetic acid HCl
CAS :Formule :C5H7ClN2O2Degré de pureté :97%Couleur et forme :SolidMasse moléculaire :162.5743Emapalumab
CAS :<p>Emapalumab (NI-0501), an IgG1 antibody, blocks interferon gamma, curbing inflammation. Used in HLH studies, it binds IFN-γ tightly (Kd=1.4 pM).</p>Degré de pureté :SDS-PAGE:95% SEC-HPLC:97.56%Couleur et forme :LiquidMasse moléculaire :145.22 kDaTheralizumab
CAS :<p>Theralizumab (TGN1412) is a monoclonal antibody for treating leukemia and arthritis by stimulating T cells.</p>Degré de pureté :95%Couleur et forme :LiquidAdrenalone hydrochloride
CAS :<p>Adrenalone HCl: α1-adrenoceptor agonist, topical hemostatic, vasoconstrictor, prolongs local anesthesia.</p>Formule :C9H11NO3·HClDegré de pureté :99.94%Couleur et forme :SolidMasse moléculaire :217.65Sabatolimab
CAS :<p>Sabatolimab (MBG453) is a humanized IgG4 antibody that inhibits TIM-3 to modulate immunity and shows promise as an immunosuppressant.</p>Degré de pureté :> 95% - > 95%Couleur et forme :LiquidMasse moléculaire :145 kDa (average)4-Hydroxyantipyrine
CAS :<p>4-Hydroxyantipyrine is formed during oxidative deamination of aminopyrine.</p>Formule :C11H12N2O2Degré de pureté :99.85%Couleur et forme :SolidMasse moléculaire :204.23Suxibuzone
CAS :<p>Suxibuzone is a prodrug for joint/muscle pain relief in horses, derived from phenylbutazone.</p>Formule :C24H26N2O6Degré de pureté :99.85%Couleur et forme :SolidMasse moléculaire :438.47N-Demethylricinine
CAS :<p>N-Demethylricinine (4-Methoxy-2-oxo-1,2-dihydro-pyridine-3-carbonitrile) was reported as xanthine oxidase inhibitor.</p>Formule :C7H6N2O2Degré de pureté :99.11%Couleur et forme :SolidMasse moléculaire :150.13Oxiracetam
CAS :<p>Oxiracetam (ISF2522), a cyclic derivative of gamma-aminobutyric acid (GABA), is utilized for the treatment of cognitive impairments.</p>Formule :C6H10N2O3Degré de pureté :99.67%Couleur et forme :White Crystalline PowderMasse moléculaire :158.16Salsalate
CAS :<p>Salsalate (Sasapyrine) is an orally available salicylate and non-steroidal anti-inflammatory drug (NSAID), with anti-inflammatory, analgesic and antipyretic</p>Formule :C14H10O5Degré de pureté :99.76%Couleur et forme :SolidMasse moléculaire :258.23BPK-29 hydrochloride
CAS :<p>"BPK-29 hydrochloride targets NR0B1, altering C274 and hinders KEAP1-mutant cancer cell growth."</p>Formule :C26H33Cl2N3O3Degré de pureté :99.06%Couleur et forme :SolidMasse moléculaire :506.46Metacetamol
CAS :<p>Metacetamol, a non-toxic acetaminophen derivative, is an OTC analgesic/antipyretic and synthesis intermediate.</p>Formule :C8H9NO2Degré de pureté :99.76% - 99.90%Couleur et forme :Physical Description Light Gray Solid (Ntp 1992)Masse moléculaire :151.166-Methoxy-2-naphthoic acid
CAS :<p>6-Methoxy-2-naphthoic acid (6-Methoxy-2-naphthalenecarboxylic acid) is an modulator of NMDAR.</p>Formule :C12H10O3Degré de pureté :99.25%Couleur et forme :White To Off-White Powder Crystals Crystalline Powder And/Or ChunksMasse moléculaire :202.21Cobolimab
CAS :<p>Cobolimab (TSR-022) is a TIM-3 antibody with IC50 of 0.4464 nM, showing antitumor effects in melanoma and liver cancer studies.</p>Degré de pureté :> 95%Couleur et forme :LiquidMasse moléculaire :142.84 kDaTheophylline
CAS :<p>Theophylline (1,3-Dimethylxanthine) is a methyl xanthine derivative from tea with diuretic, smooth muscle relaxant, bronchial dilation, cardiac and central</p>Formule :C7H8N4O2Degré de pureté :99.65% - 99.98%Couleur et forme :White Solid PowderMasse moléculaire :180.16SM-276001
CAS :<p>SM-276001 is a potent selective agonist of TLR7,and is an orally active interferon (IFN) inducer.</p>Formule :C16H21N7ODegré de pureté :99.91%Couleur et forme :SolidMasse moléculaire :327.38Baicalin
CAS :<p>Baicalin (Baicalein 7-O-β-D-glucuronide) is a prolyl endopeptidase inhibitor isolated from scutellaria baicalensis, with antioxidant, anti-tumor, anti-HIV</p>Formule :C21H18O11Degré de pureté :90.08% - 99.32%Couleur et forme :Yellow PowderMasse moléculaire :446.36Atazanavir
CAS :<p>Atazanavir (BMS-232632)(BMS-232632) is an highly effective HIV-1 protease inhibitor.</p>Formule :C38H52N6O7Degré de pureté :98% - 99.95%Couleur et forme :Crystalline SolidMasse moléculaire :704.86Articaine hydrochloride
CAS :<p>Articaine hydrochloride (Hoe-045) is a thiophene-containing local anesthetic pharmacologically similar to MEPIVACAINE.</p>Formule :C13H21ClN2O3SDegré de pureté :99.76%Couleur et forme :White Crystalline PowderMasse moléculaire :320.84CU-T12-9
CAS :<p>CU-T12-9 is a potent TLR1/2 agonist(EC50 of 52.9 nM in HEK-Blue hTLR2 SEAP assay).</p>Formule :C17H13F3N4O2Degré de pureté :99.84%Couleur et forme :SolidMasse moléculaire :362.31Brodalumab
CAS :<p>Brodalumab (AMG 827), a human IgG2 monoclonal antibody, inhibits IL-17R, treating psoriasis.</p>Degré de pureté :98.3%Couleur et forme :LiquidMasse moléculaire :144.06 kDaRisankizumab
CAS :<p>Risankizumab (BI 655066) is a monoclonal antibody for psoriasis, targeting IL-23, with high affinity (Kd <10 pM) and an IC50 of 2 pM.</p>Degré de pureté :SDS-PAGE:95.3%;SEC-HPLC:98.3%Couleur et forme :LiquidMasse moléculaire :145.85 kDaHistamine dihydrochloride
CAS :Formule :C5H11Cl2N3Degré de pureté :96%Couleur et forme :SolidMasse moléculaire :184.0669Ibritumomab
<p>Ibritumomab is a murine-derived anti-CD20 monoclonal antibody that kills tumor cells by forming free radicals in target cells and surrounding tissues.</p>Degré de pureté :96% (SDS-PAGE); 95.9% (SEC-HPLC) - 96% (SDS-PAGE); 95.9% (SEC-HPLC)Couleur et forme :Odour LiquidAChE-IN-82
<p>AChE-IN-82 (compound 49) is an acetylcholinesterase (AChE) inhibitor. It inhibits eeAChE, eqBChE, hMAO-A, hMAO-B, and BACE-1 with IC50 values of 0.072, 9.81, 14.52, 0.024, and 2.42 μM, respectively. Additionally, AChE-IN-82 inhibits COX-1, COX-2, and 5-LOX with IC50 values of 60.41, 0.187, and 0.18 μM, respectively. The compound also demonstrates strong neuroprotective effects by significantly reducing H2O2-induced oxidative stress.</p>Formule :C21H18N4O5S2Couleur et forme :SolidMasse moléculaire :470.52Coltuximab
<p>Coltuximab is a humanized anti-CD19 antibody that can be used to synthesize ADC compounds (Coltuximab Ravtansine).</p>Degré de pureté :95.3% (SDS-PAGE); 98.6% (SEC-HPLC) - 95.3% (SDS-PAGE); 98.6% (SEC-HPLC)Couleur et forme :Odour LiquidSjDX5-271
CAS :<p>SjDX5-271 is a 3 kDa peptide that inhibits the TLR4/MyD88/NF-κB signaling pathway. It induces cell polarization, alleviates liver inflammation, and protects mice from liver ischemia-reperfusion injury.</p>Formule :C137H215N47O49SCouleur et forme :SolidMasse moléculaire :3336.52ABTIM3-hum03
<p>ABTIM3-hum03 is a humanized anti-TIM3 blood-brain barrier shuttling monoclonal antibody.</p>Degré de pureté :97.6% (SDS-PAGE); 98.6% (SEC-HPLC) - 97.6% (SDS-PAGE); 98.6% (SEC-HPLC)Couleur et forme :Odour LiquidNemvaleukin alfa
CAS :<p>Nemvaleukin alfa (ALKS 4230) is an interleukin 2 fusion protein that is a selective agonist of the medium-affinity IL-2 receptor.</p>Degré de pureté :98.4% (SDS-PAGE); 98.3% (SEC-HPLC) - 98.4% (SDS-PAGE); 98.3% (SEC-HPLC)Couleur et forme :LiquidNrf2/HO-1 activator 3
<p>Nrf2/HO-1 Activator 3 (Compound C3a) is an activator of the Nrf2 signaling pathway that facilitates the translocation of Nrf2 into the nucleus and enhances the expression of heme oxygenase-1 (HO-1). In H9c2 cardiomyocytes subjected to H2O2 or high glucose stimulation, Nrf2/HO-1 Activator 3 inhibits the excessive expression of ROS and MDA, suppressing cell viability and colony formation, thereby exhibiting antioxidant activity.</p>Formule :C27H26N2O6Couleur et forme :SolidMasse moléculaire :474.51NBD peptide
CAS :<p>NBD peptide inhibits the NF-κB signaling pathway by preventing the binding of the NEMO-IKK complex. It exhibits anti-inflammatory activity by blocking the production of pro-inflammatory cytokines. Additionally, NBD peptide demonstrates immunosuppressive effects through the regulation of immune cells. It enhances transmembrane capacity by conjugating with the cell-penetrating peptide HIV-TAT.</p>Formule :C62H88N14O20Couleur et forme :SolidMasse moléculaire :1349.44(R)-Zadavotide guraxetan
CAS :<p>Zadavotide guraxetan (PSMAI&T; PNT-2002) is an inhibitor of prostate-specific membrane antigen (PSMA) with potential antitumor activity, and it is useful for research targeting prostate cancer.</p>Formule :C63H92IN11O23Couleur et forme :SolidMasse moléculaire :1498.37Simlukafusp alfa
CAS :<p>Simlukafusp alfa (FAP-IL2v) is a tumor-targeting immune cytokine, a human IgG1 antibody with antitumor activity and immunostimulatory properties.</p>Degré de pureté :97.3% (SDS-PAGE); 94.3% (SEC-HPLC) - 97.3% (SDS-PAGE); 94.3% (SEC-HPLC)Couleur et forme :Liquid4-ACETAMIDOANTIPYRINE
CAS :<p>4-ACETAMIDOANTIPYRINE, with CAS No. 83-15-8, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 4-ACETAMIDOANTIPYRINE provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.</p>Formule :C13H15N3O2Couleur et forme :SolidMasse moléculaire :245.28STING agonist-17
CAS :<p>STING agonist-17 (compound 4a) is a highly potent stimulator of the STING pathway, exhibiting an IC 50 of 0.062 nM.</p>Formule :C43H53N13O8Couleur et forme :SolidMasse moléculaire :879.96C2 Ceramide (d14:1/2:0)
CAS :<p>C2 Ceramide (d14:1/2:0), a bioactive sphingolipid, causes lipotoxic cardiomyopathy when fed to Drosophila at 100 μM.</p>Formule :C16H31NO3Couleur et forme :SolidMasse moléculaire :285.42C12-rrw-NH2
<p>C12-rrw-NH2 (Compound Lip7) is an antimicrobial agent effective against Gram-positive bacteria, particularly demonstrating significant activity against Methicillin-resistant Staphylococcus aureus (MRSA). It induces bacterial cell death by depolarizing the bacterial cell membrane, disrupting membrane integrity, causing nucleic acid and protein leakage, and promoting the generation of Reactive Oxygen Species (ROS). C12-rrw-NH2 is applicable in research focused on developing highly stable antimicrobial peptides.</p>Formule :C35H58N10O5Couleur et forme :SolidMasse moléculaire :698.9KD014
<p>KD014 (DX-2400) is a human monoclonal antibody (mAb) that targets MMP14, with a Ki of 0.9 nM. It inhibits TGFβ and SMAD2/3 signaling, increases macrophage count and iNOS expression, and shifts macrophage phenotype towards an antitumor M1-like type. KD014 exhibits antitumor activity in three tumor models (MDA-MB-231, MDA-MB-435, and PC3) and is applicable in breast cancer research.</p>Couleur et forme :Odour LiquidPMX 205 Trifluoroacetate
<p>PMX 205 Trifluoroacetate is a potent complement C5a receptor ( C5aR ; CD88 ) antagonist.</p>Formule :C47H63F3N10O8Couleur et forme :SolidMasse moléculaire :953.06Tetrachlorohydroquinone
CAS :<p>TCHQ, a pentachlorophenol metabolite, toxic to trout liver cells, increases ROS, disrupts mitochondria, and causes necrosis in splenocytes. EC50: 1.55 μM.</p>Formule :C6H2Cl4O2Couleur et forme :SolidMasse moléculaire :247.89FITC-labeled ODN 1826 sodium
<p>FITC-labeled ODN 1826 (sodium), a class B CpG ODN (oligodeoxynucleotide) and TLR9 agonist, facilitates the assessment of CpG ODN cellular uptake and</p>Couleur et forme :Odour SolidPF-06426779
CAS :<p>PF-06426779 is a potent and selective inhibitor of interleukin 1 receptor associated kinase 4 (IRAK4) , with an IC 50 of 0.3 nM.</p>Formule :C17H18FN3O4Couleur et forme :SolidMasse moléculaire :347.346Ladanetin-6-O-β-D-glucopyranoside
CAS :<p>Ladanetin-6-O-β-D-glucopyranoside, an active flavonoid, exhibits antioxidative effects and has potential for research into cardioprotective effects [1].</p>Formule :C22H22O11Couleur et forme :SolidMasse moléculaire :462.4Benz-AP
CAS :<p>Benz-AP: potent photosensitizer, creates singlet oxygen, more toxic in low hCES2 cancer cells, generates ROS via TPE to kill tumors.</p>Formule :C20H13NO2Couleur et forme :SolidMasse moléculaire :299.32
