Immunologie et Inflammation
Les inhibiteurs en immunologie et inflammation sont des composés qui modulent la réponse immunitaire et les processus inflammatoires. Ces inhibiteurs sont cruciaux pour étudier les mécanismes de la régulation immunitaire, l'auto-immunité et l'inflammation chronique, ainsi que pour développer des traitements pour les maladies inflammatoires, les allergies et les troubles immunitaires. En ciblant des voies clés du système immunitaire, ces inhibiteurs peuvent aider à réduire les réponses immunitaires excessives ou inappropriées. Chez CymitQuimica, nous offrons une large sélection d'inhibiteurs de haute qualité en immunologie et inflammation pour soutenir vos recherches en immunologie, inflammation et développement thérapeutique.
Sous-catégories appartenant à la catégorie "Immunologie et Inflammation"
- RCC(136 produits)
- CXCR(147 produits)
- Paroi cellulaire(5 produits)
- Récepteur IL(113 produits)
- IκB/IKK(61 produits)
- LTR(3 produits)
- MALT(23 produits)
- MRP(6 produits)
- NADPH-oxydase(1 produits)
- NF-κB(445 produits)
- NOD(17 produits)
- NOS(63 produits)
- Nrf2(78 produits)
- PGE Synthase(31 produits)
- ROS(69 produits)
- TGF-beta/Smad(58 produits)
- TLR(66 produits)
- Thioredoxine(12 produits)
- gp120/CD4(4 produits)
Affichez 11 plus de sous-catégories
3035 produits trouvés pour "Immunologie et Inflammation"
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Olendalizumab
CAS :<p>Olendalizumab (ALXN1007) is a humanized antibody targeting C5a for research on COVID-19-related inflammation.</p>Couleur et forme :LiquidSuc-Tyr-Val-Ala-Asp-pNA
CAS :<p>Suc-YVAD-pNA, a chromogenic caspase-1 substrate.</p>Formule :C31H38N6O12Couleur et forme :SolidMasse moléculaire :686.675M0324
<p>M0324 is a MUC-1 conditional CD40 agonist composed of an anti-MUC-1 IgG and two identical CD40-targeting camelid VHH domains, selectively activate immune cells.</p>Couleur et forme :Odour LiquidDibenzothiophene
CAS :<p>Dibenzothiophene, a sulfur PAH in petroleum, has 3 rings and keratolytic properties.</p>Formule :C12H8SDegré de pureté :99.82%Couleur et forme :Yellow To Green SolidMasse moléculaire :184.265(S),15(S)-DiHETE
CAS :<p>5(S),15(S)-DiHETE, made by 15-LO from 5(S)-HETE, boosts human PMNL degranulation via PAF, not fMLP/A23187/LTB4, and lures eosinophils at ED50 of 0.3μM.</p>Formule :C20H32O4Couleur et forme :SolidMasse moléculaire :336.472Rabelomycin
CAS :<p>Rabelomycin is an angucycline group antibiotic.</p>Formule :C19H14O6Couleur et forme :SolidMasse moléculaire :338.31BMP-4
CAS :<p>BMP-4, a heparin-binding peptide, exhibits anti-inflammatory and anti-chondrogenic properties. In murine chondrocytes and macrophages, it effectively mitigates inflammation and alleviates symptoms of various arthritides by dose-dependently suppressing the expression of inflammatory proteins such as iNOS, COX2, IFN, and IL6 through modulation of the iNOS-IFN-IL6 signaling pathway.</p>Formule :C52H93N25O13SCouleur et forme :SolidMasse moléculaire :1308.52C6 L-threo Ceramide (d18:1/6:0)
CAS :<p>C6 L-threo Ceramide: bioactive sphingolipid, cytotoxic to U937 cells (IC50=18μM), non-metabolic, boosts IL-4 in T cells at 10μM.</p>Formule :C24H47NO3Couleur et forme :SolidMasse moléculaire :397.63Anti-inflammatory agent 64
<p>Anti-inflammatory agent 64 (compound 4b) exhibits antioxidant and anti-inflammatory activities, effectively inhibiting the secretion of IL-6 and TNF-α while</p>Degré de pureté :98%Couleur et forme :Odour SolidGinger extract
CAS :<p>Ginger extract demonstrates (exhibits) anti-cancer, anti-inflammatory, and chemotherapeutic properties in living organisms (in vivo).</p>Couleur et forme :SolidNOX4-IN-1
<p>NOX4-IN-1 (Compound 14m) is an inhibitor of NADPH oxidase 4 (NOX4) that reduces the production of reactive oxygen species (ROS). It also inhibits the TGF-β1/Smad signaling pathway, leading to decreased expression of fibrosis-related proteins. Additionally, NOX4-IN-1 impedes the migration of NRK-49F cells.</p>Formule :C26H16ClN3O3Couleur et forme :SolidMasse moléculaire :453.877DEPMPO-biotin
CAS :<p>DEPMPO is a stable nitrone for trapping O, N, S, C radicals, used in vivo/vitro with ESR. DEPMPO-biotin tags proteins' S-nitroso groups for analysis.</p>Formule :C24H42N5O8PSCouleur et forme :SolidMasse moléculaire :591.66Croconazole
CAS :<p>Croconazole exhibited dose-dependent inhibitory activity on the 5-lipoxygenase (5-LOX) of neutrophils.</p>Formule :C18H15ClN2ODegré de pureté :99.71%Couleur et forme :SolidMasse moléculaire :310.78Perfluorohexane
CAS :<p>Perfluorohexane (AF-0150) is a perfluorocarbon (PFC)-based microbubble formulation for ultrasound contrast and is developmentally toxic.</p>Formule :C6F14Degré de pureté :98%Couleur et forme :Colourless LiquidMasse moléculaire :338.04Diplacol
CAS :<p>Diplacol, a geranylated flavanone isolated from Paulownia trees (Paulownia coreana UYEKI), exhibits anti-inflammatory properties by inhibiting NO production in LPS-stimulated Raw264.7 cells with an IC50 value of 4.53 μM [1].</p>Formule :C25H28O7Couleur et forme :SolidMasse moléculaire :440.49Cartap hydrochloride
CAS :<p>Cartap hydrochloride is an insecticidal derivative. It is used to control chewing and sucking insects on many crops.</p>Formule :C18H33Cl2CuN3O3Couleur et forme :Colorless Crystalline Slightly Hygroscopic Solid CoaMasse moléculaire :473.93CD19 CAR mRNA
<p>CD19 CAR mRNA expresses a protein for use in CAR-CD19 T cell therapy, targeting B cell antigen for cancer treatment.</p>Couleur et forme :SolidCanakinumab
CAS :<p>Canakinumab: Human IL-1β antibody, anti-inflammatory, treats gout & coronary disease, IC50 of 43.6 pM (human), 40.8 pM (monkey).</p>Degré de pureté :98.8%Couleur et forme :LiquidMasse moléculaire :145.18 kDaReltecimod TFA
<p>Reltecimod TFA (AB-103 TFA) is a CD28 antagonist and mimetic, inhibiting the stimulation of t-cells thereby attenuating acute inflammation NSTI.</p>Formule :C48H73F3N10O17SDegré de pureté :99.24% - 99.78%Couleur et forme :SolidMasse moléculaire :1151.21CD19 CAR circRNA
<p>CD19 CAR circRNA expresses a CD19 car protein for CAR-T immunotherapy targeting B-cell antigens.</p>Couleur et forme :SolidIM-250
CAS :<p>IM-250 possesses antiviral activity with IC values of 25 nM - 100 nM.</p>Formule :C20H19F2N3O2S2Degré de pureté :99.59%Couleur et forme :SoildMasse moléculaire :435.51CD22 ligand-1
CAS :<p>CD22 ligand-1 is a potent, selective hCD22 binder (K D 0.335 µM) with potential for B-cell disease research.</p>Formule :C33H34N5NaO10Couleur et forme :SolidMasse moléculaire :683.64Anti-inflammatory agent 58
<p>Anti-inflammatory agent 58 exhibits IL-1β inhibition with an IC50 value of 1.08 μM and suppresses pro-inflammatory gene expression, protein secretion, and NF-κB</p>Couleur et forme :Odour SolidEblasakimab
CAS :<p>Eblasakimab (ASLAN004) is a humanized monoclonal antibody targeting IL-13α, which blocks IL-4 and IL-13 signaling through the type II receptor.</p>Degré de pureté :＞95%Couleur et forme :LiquidPF-06342674
<p>PF-06342674 is a humanized monoclonal antibody targeting the IL-7 receptor-α, with immunoregulatory activity, used in Type 1 diabetes research.</p>Couleur et forme :LiquidMasse moléculaire :145.5kDa3-(2-Hydroxyethyl) thio withaferin A
<p>3-(2-Hydroxyethyl) thio withaferin A, a steroidal lactone, blocks NF-kB, targets vimentin, and inhibits EPCR shedding.</p>Formule :C30H44O7SCouleur et forme :SolidMasse moléculaire :548.73R1-ICR-5
CAS :<p>R1-ICR-5 is a selective PROTAC degrader targeting serine/threonine-protein kinase 1 (RIPK1). Mediated by VHL, R1-ICR-5 promotes the degradation of RIPK1, disrupting the TNFR1 and TLR3/4 signaling hubs, enhancing NF-κB, MAPK, and IFN signal output, and facilitating RIPK3 activation and necroptosis induction. R1-ICR-5 holds potential for research in cancer and inflammatory diseases.</p>Formule :C54H70N8O7S2Couleur et forme :SolidMasse moléculaire :1007.314-Chlorochalcone
CAS :<p>4-Chlorochalcone is achalcone inhibit human MAO-B and ROS/RNS production and is able to inhibit the growth of CAL51 cells.</p>Formule :C15H11ClODegré de pureté :98.08%Couleur et forme :SolidMasse moléculaire :242.7Camstatin
CAS :<p>An analog of PEP-19 with enhanced binding to and antagonism of calmodulin.</p>Formule :C122H203N39O34Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :2760.19MUC1, mucin core
CAS :<p>MUC1: Type I transmembrane glycoprotein, overexpressed and abnormally glycosylated in cancer, binds ICAM-1 domain 1.</p>Formule :C61H101N19O24Couleur et forme :SolidMasse moléculaire :1484.588Septeremophilane E
<p>Septeremophilane E, from Septoria rudbeckiae fungus, inhibits NO production.</p>Formule :C21H26O5Couleur et forme :SolidMasse moléculaire :358.43Anticonvulsant agent 10
<p>Anticonvulsant agent 10 (Compound 6d) is an inhibitor targeting the Keap1-Nrf2 interaction, with a strong activity showing an ED50 of 0.04 mmol/kg. By inhibiting the Keap1-Nrf2 binding, it activates the Nrf2/ARE pathway, providing anticonvulsant and neuroprotective effects, making it useful for research in epilepsy and neuroprotection.</p>Couleur et forme :Odour SolidCOX-2/15-LOX-IN-4
<p>COX-2/15-LOX-IN-4 (compound 5i) is a dual inhibitor with IC50 values of 0.075 μM for COX-2 and 1.97 μM for 15-LOX.</p>Formule :C23H20FN3OSDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :405.49NLRP3-IN-12
<p>NLRP3-IN-12 inhibits NLRP3 inflammasome, curbing IL-1β release with 0.45 μM IC50, for inflammatory bowel disease research.</p>Formule :C27H32ClNO7Couleur et forme :SolidMasse moléculaire :518DC 07090
CAS :<p>DC 07090 is a human enterovirus 71 3C protease inhibitor with antiviral activity for the study of nucleic acid virus infections.</p>Formule :C18H14N4ODegré de pureté :97.34%Couleur et forme :SolidMasse moléculaire :302.33CRX-526
CAS :<p>CRX-526, a TLR4 antagonist, protects against advanced diabetic nephropathy.</p>Formule :C69H127N2O19PDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :1319.72Amaroswerin
CAS :<p>Amaroswerin, a secoiridoid glucoside, has anti-inflammatory, antidiabetic, and other medicinal properties; it inhibits NO release at IC50 of 5.42 μg/mL.</p>Formule :C29H30O14Couleur et forme :SolidMasse moléculaire :602.54AM-103 Free Acid
CAS :<p>AM-103 Free Acid is a bio-active chemical.</p>Formule :C36H39N3O4SCouleur et forme :SolidMasse moléculaire :609.78NLRP3-IN-15
CAS :<p>NLRP3-IN-15: potent, selective NLRP3 inflammasome inhibitor; IC50 0.114 μM for IL-1β; for inflammation research.</p>Formule :C22H19NO4Couleur et forme :SolidMasse moléculaire :361.39QX006N
<p>QX006N is a humanized monoclonal antibody inhibitor targeting the human interferon α/β receptor 1 (IFNAR1). It is promising for research in systemic lupus erythematosus (SLE) and other IFNAR1-related autoimmune diseases.</p>Couleur et forme :Odour LiquidBCL6 PROTAC 1
CAS :<p>BCL6 PROTAC 1: Selective BCL6 degrader, IC50 8.8 µM, used in DLBCL research.</p>Formule :C45H52ClN9O12Couleur et forme :SolidMasse moléculaire :946.41-Hydroxy-ibuprofen
CAS :<p>1-Hydroxy Ibuprofen, a metabolite in P. australis, targets COX-1/COX-2 with IC50s: 13 μM/370 μM.</p>Formule :C13H18O3Couleur et forme :SolidMasse moléculaire :222.2802Crocin-4
CAS :<p>Crocin-4, a saffron carotenoid, is an antioxidant that inhibits Aβ deposits in the brain and may aid Alzheimer's research with anti-tumor effects.</p>Formule :C27H36O9Couleur et forme :SolidMasse moléculaire :504.576KTX-612
CAS :<p>KTX-612 is a compound that serves as an orally active IRAK4 degrader, exhibiting a DC50 value of 7 nM. It is primarily utilized in oncology research [1].</p>Formule :C46H51F3N8O6Couleur et forme :SolidMasse moléculaire :868.947-epi Maresin 1
CAS :<p>7-epi Maresin 1 is the inactive 7(S) epimer of Maresin 1 , which contains a 7(R) hydroxyl group. It can be used as an experimental negative control.</p>Formule :C22H32O4Couleur et forme :SolidMasse moléculaire :360.494E7766 disodium
CAS :<p>E7766 disodium, a macrocycle-bridged STING agonist, exhibits a binding affinity (Kd) of 40 nM, demonstrating potent pan-genotypic and antitumor effects.</p>Formule :C24H26F2N10Na2O8P2S2Couleur et forme :SolidMasse moléculaire :792.58Maritimetin
CAS :<p>Maritimein, an aurone from Coreopsis tinctoria, has potent antioxidant activity (IC50: 4.12 μM) and is used in cardiovascular research.</p>Formule :C15H10O6Couleur et forme :SolidMasse moléculaire :286.24Dihydrorhodamine 6G
CAS :<p>DHR 6G, nonfluorescent reduced Rhodamine 6G, permeates cells, indicating ROS by oxidizing to fluorescent form in mitochondria.</p>Formule :C28H32N2O3Couleur et forme :SolidMasse moléculaire :444.57UT-11
<p>UT-11: potent, brain-permeable mPGES-1 inhibitor. IC50: 0.10μM (human SK-N-AS), 2.00μM (murine BV2). Stops PGE2 production.</p>Formule :C17H19Cl2N3O2SCouleur et forme :SolidMasse moléculaire :400.32EB-TCIP
<p>EB-TCIP (BAK-04-212) is a bivalent molecule composed of AP1867 and BI-3812. It facilitates the reversible formation of a ternary complex between FKBPF36V and BCL6BTB, thereby recruiting FKBP12F36V-tagged EWS/FLI1 to DNA sites bound by the transcriptional regulator BCL6, rapidly inducing expression of BCL6 target genes such as SOCS2 and CXCL11. EWS/FLI1 is a fusion transcription factor found in Ewing sarcoma. EB-TCIP is applicable for studying transcriptional dysregulation in cancer.</p>Couleur et forme :Odour Solid
