Immunologie et Inflammation
Les inhibiteurs en immunologie et inflammation sont des composés qui modulent la réponse immunitaire et les processus inflammatoires. Ces inhibiteurs sont cruciaux pour étudier les mécanismes de la régulation immunitaire, l'auto-immunité et l'inflammation chronique, ainsi que pour développer des traitements pour les maladies inflammatoires, les allergies et les troubles immunitaires. En ciblant des voies clés du système immunitaire, ces inhibiteurs peuvent aider à réduire les réponses immunitaires excessives ou inappropriées. Chez CymitQuimica, nous offrons une large sélection d'inhibiteurs de haute qualité en immunologie et inflammation pour soutenir vos recherches en immunologie, inflammation et développement thérapeutique.
Sous-catégories appartenant à la catégorie "Immunologie et Inflammation"
- RCC(136 produits)
- CXCR(147 produits)
- Paroi cellulaire(5 produits)
- Récepteur IL(113 produits)
- IκB/IKK(61 produits)
- LTR(3 produits)
- MALT(23 produits)
- MRP(6 produits)
- NADPH-oxydase(1 produits)
- NF-κB(445 produits)
- NOD(17 produits)
- NOS(63 produits)
- Nrf2(78 produits)
- PGE Synthase(31 produits)
- ROS(69 produits)
- TGF-beta/Smad(58 produits)
- TLR(66 produits)
- Thioredoxine(12 produits)
- gp120/CD4(4 produits)
Affichez 11 plus de sous-catégories
3035 produits trouvés pour "Immunologie et Inflammation"
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DDO-7263
CAS :<p>DDO-7263, a 1,2,4-Oxadiazole, boosts Nrf2 by binding Rpn6, blocking 26S proteasome assembly, and has anti-inflammatory effects.</p>Formule :C14H9F2N3ODegré de pureté :99.85%Couleur et forme :SolidMasse moléculaire :273.24Keap1-Nrf2-IN-16
CAS :<p>Keap1-Nrf2-IN-16 is a biologically active peptide with KEAP1 binding activity.</p>Formule :C73H114N16O26Couleur et forme :SolidMasse moléculaire :1631.78AMPCP
CAS :<p>AMPCP is an Ecto-5'-nucleotidase (CD73) inhibitor.</p>Formule :C11H15N5Na2O9P2Couleur et forme :SolidMasse moléculaire :469.194-CPPC
CAS :<p>4-CPPC inhibits MIF-2 (IC50=27μM), not MIF-1; blocks MIF-2/CD74 binding and MIF-2-induced ERK1/2 in fibroblasts.</p>Formule :C14H9NO6Degré de pureté :97.50% - 98.03%Couleur et forme :SolidMasse moléculaire :287.22Fenquinotrione
CAS :<p>Fenquinotrione, a 4-hydroxyphenylpyruvate dioxygenase (HPPD) inhibitor, exhibits IC50 values of 27.2 and 44.7 nM against HPPD from rice and Arabidopsis thaliana</p>Formule :C22H17ClN2O5Couleur et forme :SolidMasse moléculaire :424.83TLR8 agonist 5
CAS :<p>TLR8 Agonist 5, exhibiting potent efficacy as a TLR8 agonist, demonstrates an EC50 of 20 nM in HEK-Blue hTLR8, effectively activating the immune response.</p>Formule :C31H40N6O5Couleur et forme :SolidMasse moléculaire :576.69PK68
CAS :<p>PK68 selectively inhibits RIPK1 (IC50=90nM), potentially useful in inflammation and cancer metastasis studies.</p>Formule :C22H24N4O3SDegré de pureté :98.09% - 99.64%Couleur et forme :SolidMasse moléculaire :424.52ML-090
CAS :<p>ML-090 is NOX1-specific inhibitor(IC50 = 90 nM) which is >100 selectivity for NOX1 over NOX2, NOX3, NOX4 (all IC50s >10 μM).</p>Formule :C14H10N4Degré de pureté :98.55%Couleur et forme :SolidMasse moléculaire :234.26Glabrescone C
CAS :<p>Glabrescone C exhibits strong anti-inflammatory properties through direct binding to IKKα/β.</p>Formule :C19H22O7Couleur et forme :SolidMasse moléculaire :362.37TLR7/8 agonist 8
CAS :<p>TLR7/8 agonist 8 (compound 24m) is a potent dual agonist for toll-like receptors 7 and 8 (TLR7/8), exhibiting half-maximal effective concentrations (EC50s) of</p>Formule :C24H30N6OCouleur et forme :SolidMasse moléculaire :418.53PF 184
CAS :<p>IKKβ inhibitor</p>Formule :C32H32ClFN6O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :619.09NLRP3-IN-9
CAS :<p>NLRP3-IN-9 (INF-4E) irreversibly inhibits NLRP3 ATPase, caspase-1, and prevents pyroptosis in THP-1 cells.</p>Formule :C12H13ClO3Degré de pureté :99.64%Couleur et forme :SolidMasse moléculaire :240.68IKK-IN-4
CAS :<p>IKK-IN-4 is a potent and selective inhibitor of IkappaB kinase 2 with IC 50 values of 45 and 650 nM against IKKβ and IKKα, respectively [1].</p>Formule :C18H19N5SCouleur et forme :SolidMasse moléculaire :337.44DNA polymerase-IN-1
CAS :<p>DNA polymerase-IN-1 exhibits antiproliferative activity against tumor cells and inhibits Taq DNA polymerase as a DNA polymerase inhibitor.</p>Formule :C10H7ClO4Degré de pureté :99.16%Couleur et forme :SolidMasse moléculaire :226.61TLR7 agonist 23
CAS :<p>TLR7 agonist23 (compound 12b) is a potent agonist of Toll-like receptor-7 (TLR7), with an EC50 value of 0.15 uM. It is suitable for research in immune diseases.</p>Formule :C21H22N4O2Couleur et forme :SolidMasse moléculaire :362.42Arginase inhibitor 1
CAS :<p>Arginase inhibitor 1 is a potent inhibitor of human arginases I and II (IC50s: 223 and 509 nM).</p>Formule :C13H27BN2O4Couleur et forme :SolidMasse moléculaire :286.18(R)-IL-17 modulator 4
CAS :<p>(R)-IL-17 modulator 4, an R-isomer prodrug of IL-17 modulator 1, is potent and taken orally.</p>Formule :C27H34N6O2Couleur et forme :SolidMasse moléculaire :474.6Factor B-IN-2
CAS :<p>Factor B-IN-2 is a potent inhibitor (IC50: 1.5 μM) of complement factor B. Factor B-IN-2 can be used to study inflammatory and immune-related diseases.</p>Formule :C25H32N2O4Couleur et forme :SolidMasse moléculaire :424.53STING-IN-5
CAS :<p>STING-IN-5 suppresses NO synthesis in macrophages, inhibits STING pathway with IC50 of 1.15 μM, and may aid anti-inflammatory and sepsis research.</p>Formule :C47H67NO9S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :854.17Anti-inflammatory agent 46
CAS :<p>Anti-inflammatory agent 46 (compound 7h), exhibiting nitric oxide (NO) inhibitory properties, demonstrates a high affinity for iNOS through low binding energies</p>Formule :C24H19FN2O3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :434.48RIP1 kinase inhibitor 4
CAS :<p>RIP1 Kinase Inhibitor 4 (Compound 3) is an effective inhibitor of RIP1K, exhibiting an EC50 of ≤ 1000 nM [1].</p>Formule :C23H23N5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :369.46TLR4 agonist-1
CAS :<p>TLR4 agonist-1 (compound 17a) serves as a potent activator of Toll-like Receptor 4 (TLR4) and stimulates the production of MIP-1β in RAW 264.7 and MM6 cells [1</p>Formule :C81H158N3O15PCouleur et forme :SolidMasse moléculaire :1445.11hnNOS-IN-2
CAS :<p>Compound 17, also known as hnNOS-IN-2, is an inhibitor of human neuronal nitric oxide synthase (hnNOS) that exhibits good metabolic stability.</p>Formule :C18H23F2N3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :319.39Aminoguanidine hemisulfate
CAS :<p>Aminoguanidine hemisulfate, an inhibitor of nitric oxide synthases (NOS) and reactive oxygen species (ROS), effectively suppresses ANE-induced ROS production in</p>Formule :CH6N4H2SO4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :123.115IMD-biphenylC
CAS :<p>IMD-biphenylC: New, dual-action imidazoquinolinone dimer; inhibits tumor growth, low inflammation/toxicity.</p>Formule :C35H33N5O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :571.67ICy-Q
CAS :<p>ICy-Q, a NIR reagent activated by NQO-1, triggers pyroptosis in pancreatic cancer cells, aiding diagnosis.</p>Formule :C48H50I2N2O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :988.73GBT1118
CAS :<p>GBT1118 is an orally active allosteric modulator of haemoglobin oxygen affinity, enhancing tolerance to acute severe hypoxia and suitable for hypoxia research.</p>Formule :C19H20N2O4Degré de pureté :99.69%Couleur et forme :SolidMasse moléculaire :340.37TBK1-IN-1
CAS :<p>TBK1-IN-1 is a TANK-binding kinase 1 inhibitor with anticancer activity.TBK1-IN-1 inhibits the expression of TBK1 downstream target genes, cxcl10 and ifnβ.</p>Formule :C27H37N7O2Degré de pureté :>99.99%Couleur et forme :SolidMasse moléculaire :491.63Dapsone hydroxylamine
CAS :<p>Dapsone hydroxylamine (DDS-NOH) promotes methemoglobinemia, impedes catalase (CAT) activity, and suppresses the generation of reactive oxygen species, while</p>Formule :C12H12N2O3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :264.3NLRP3-IN-21
CAS :<p>NLRP3-IN-21 (compound L38) is an inhibitor of the NLRP3 inflammasome that possesses anti-inflammatory properties.</p>Formule :C20H13Cl2F3N6O2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :529.32MALT1-IN-7
CAS :<p>MALT1-IN-7 (compound 142b) is a potent inhibitor of MALT1 protease with potential for cancer research.</p>Formule :C19H17F3N8O2SCouleur et forme :SolidMasse moléculaire :478.45IMD-vanillin
CAS :<p>IMD-vanillin is a novel compound characterized as an imidazoquinolinone-derived dimer with NF-κB immunomodulatory properties.</p>Formule :C37H45N7O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :651.8IRAK4-IN-28
CAS :<p>IRAK4-IN-28 (compound 42), an orally-active IRAK4 inhibitor (IC50=8.9 nM), exhibits strong binding affinity with a Kd of 0.58 nM for the target enzyme.</p>Formule :C27H31N9O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :529.59CCT374705
CAS :<p>CCT374705, an orally active BCL6 inhibitor, exhibits potent antiproliferative effects in vitro and effectively inhibits tumor growth in a lymphoma xenograft</p>Formule :C21H18ClF3N4O2Couleur et forme :SolidMasse moléculaire :450.84Galectin-3 antagonist 2
CAS :<p>Galectin-3: a lectin aiding BCP-ALL cell migration & drug resistance.</p>Formule :C22H23NO10Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :461.42BF738735
CAS :<p>BF738735 is a selective inhibitor of phosphatidylinositol 4-kinase III beta (PI4KIIIβ, IC50 = 5.7 nM) showing higher activity over α(IC50 = 1.7 μM).</p>Formule :C21H19FN4O3SDegré de pureté :90%Couleur et forme :SolidMasse moléculaire :426.46RIPK2-IN-3
CAS :<p>RIPK2-IN-3 (FCG806791773) is a RIPK2 inhibitor with anti-inflammatory and anticancer activities, useful for research on immune diseases and cancer.</p>Formule :C25H22N4O2Degré de pureté :99.57%Couleur et forme :SolidMasse moléculaire :410.47h-NTPDase-IN-3
CAS :<p>h-NTPDase-IN-3 is an h-NTPDase inhibitor that inhibits h-NTPDase1, h-NTPDase2, h-NTPDase3 and h-NTPDase8.</p>Formule :C16H10N4SDegré de pureté :98.24%Couleur et forme :SolidMasse moléculaire :290.34NVS-MALT1
CAS :<p>NVS-MALT1 is an allosteric inhibitor of MALT1 [1].</p>Formule :C24H27ClF3N5O4SCouleur et forme :SolidMasse moléculaire :574.02(-)-Bornyl ferulate
CAS :<p>(-)-Bornyl ferulate is a dual inhibitor of 5-lipoxygenase and cyclooxygenase (COX), exhibiting half-maximal inhibitory concentrations (IC50s) of 10.4 μM for 5-</p>Formule :C20H26O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :330.42Antitumor agent-114
CAS :<p>Antitumor Agent-114, a potent STING (stimulator of interferon genes) agonist, activates immune responses and diminishes tumor size in mouse breast cancer models</p>Formule :C39H50F2N10O13P2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :966.82NF-κB-IN-13
CAS :<p>NF-κB-IN-13 (compound 12) markedly suppresses LPS-induced NF-κB activation and NO synthesis in RAW264.7 macrophages, exhibiting anti-inflammatory properties [1</p>Formule :C20H20O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :340.37BI 7446
CAS :<p>BI 7446 is a potent and selective cyclic dinucleotide (CDN)-based stimulator of interferon genes (STING) agonist capable of activating all five STING variants</p>Formule :C20H22FN9O10P2S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :693.52CD73-IN-6
CAS :<p>CD73-IN-6, serves as a potent inhibitor of CD73. This compound finds utility in cancer research [1].</p>Formule :C20H15N7O2Couleur et forme :SolidMasse moléculaire :385.38FCE-27164
CAS :<p>FCE-27164 inhibits PDGF-β and IL-7 receptor binding, potentially modulating inflammatory and immune responses for therapeutic applications.</p>Formule :C45H34N10Na6O23S6Degré de pureté :96.04%Couleur et forme :SolidMasse moléculaire :1413.11Dexamethasone palmitate
CAS :<p>DXP, a lipophilic prodrug of Dexamethasone, has 47x less glucocorticoid receptor affinity; it's an agonist & anti-inflammatory.</p>Formule :C38H59FO6Degré de pureté :99.28%Couleur et forme :SolidMasse moléculaire :630.87CD73-IN-10
CAS :<p>CD73-IN-10, a potent inhibitor of CD73, aids in creating cancer drugs by hindering adenosine synthesis, which fosters tumor growth.</p>Formule :C15H13F2N5O2Couleur et forme :SolidMasse moléculaire :333.29TLR7 agonist 14
CAS :<p>Compound 17b, a TLR7 agonist also known as TLR7 agonist 14, exhibits high potency with an EC50 of 18 nM.</p>Formule :C29H36N6O3Couleur et forme :SolidMasse moléculaire :516.63BD-AcAc 2
CAS :<p>BD-AcAc 2 (Ketone Ester) is a ketone monoester and can be used as a source of oral nutritional ketones.</p>Formule :C8H16O4Degré de pureté :99.62%Couleur et forme :SolidMasse moléculaire :176.21NLRP3-IN-18
CAS :<p>NLRP3-IN-18, also known as compound 13, is a potent inhibitor of NLRP3, demonstrating an IC50 value of ≤1.0 µM [1].</p>Formule :C19H18ClN3ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :339.82
