NF-κB
Le facteur nucléaire kappa B (NF-κB) est un facteur de transcription qui régule l'expression des gènes impliqués dans les réponses immunitaires, l'inflammation, la survie cellulaire et la prolifération. Le NF-κB est activé en réponse à divers stimuli, y compris les cytokines, les agents pathogènes et les signaux de stress. La dérégulation de la signalisation du NF-κB est associée à des maladies inflammatoires chroniques, au cancer et aux troubles auto-immuns. Chez CymitQuimica, nous offrons une sélection complète de modulateurs de la voie NF-κB pour soutenir vos recherches en inflammation, oncologie et régulation immunitaire.
445 produits trouvés pour "NF-κB"
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PS 1145 dihydrochloride
CAS :<p>IκB kinase (IKK) inhibitor</p>Formule :C17H13Cl3N4ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :395.67Nasunin
CAS :<p>Delphanin, also known as Nasunin, is an anthocyanin isolated as purple colored crystals from eggplant peels.</p>Formule :C42H47ClO23Couleur et forme :SolidMasse moléculaire :955.26Siegesbeckialide I
<p>Siegesbeckialide I effectively suppresses LPS-induced NO production in RAW264.7 murine macrophages by directly interacting with IKKα/β.</p>Formule :C20H28O6Couleur et forme :SolidMasse moléculaire :364.43NF-κB Signaling Compound Library
<p>A unique collection of xnum compounds targeting NF-κB signaling for high throughput screening and high content screening;</p>Couleur et forme :Odour SolidMesalamine impurity P
CAS :<p>Mesalamine impurity P, a 5-Aminosalicylic acid derivative, is a PPARγ agonist, inhibiting PAK1 and NF-κB.</p>Formule :C13H11NO6SCouleur et forme :SolidMasse moléculaire :309.30NF-κΒ activator 1
CAS :<p>NF-κΒ activator 1 can activate the nf-kappa Β gene activator, EC50 of 0.9 microns.</p>Formule :C16H11FN2O2SDegré de pureté :99.58%Couleur et forme :SolidMasse moléculaire :314.333-(2-Hydroxyethyl) thio withaferin A
<p>3-(2-Hydroxyethyl) thio withaferin A, a steroidal lactone, blocks NF-kB, targets vimentin, and inhibits EPCR shedding.</p>Formule :C30H44O7SCouleur et forme :SolidMasse moléculaire :548.73PROTAC STING degrader-3
<p>PROTACSTING degrader-3 (Compound ST9) is a STINGPROTAC-type degrader with a DC50 of 0.62 μM. It induces STING degradation via the ubiquitin-proteasome pathway. This compound exerts anti-inflammatory effects by inhibiting the STING/TBK1/NF-κB signaling. Additionally, it offers renal protection and can be used in research on acute kidney injury.</p>Couleur et forme :Odour SolidLemnalol
CAS :<p>Lemnalol, from Lemnalia cervicorni, has anti-inflammatory and analgesic properties.</p>Formule :C15H24ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :220.35Licoagrochalcone C
CAS :<p>Licoagrochalcone C, a flavonoid, inhibits NF-κB and NO production effectively.</p>Formule :C21H22O5Couleur et forme :SolidMasse moléculaire :354.4TBK1/IKKε-IN-6
CAS :<p>TBK1/IKKε-IN-6 (example 110) is a potent inhibitor of TBK1 and IKKε, with IC50 values of less than 100 nM for both enzymes.</p>Formule :C31H36F2N8O4Couleur et forme :SolidMasse moléculaire :622.678Helenalin
CAS :<p>Helenalin: anti-inflammatory sesquiterpene, inhibits NF-κB by alkylating p65 cysteine groups, blocks DNA binding.</p>Formule :C15H18O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :262.3NF-κB-IN-9
<p>NF-κB-IN-9, a nuclear factor kappa B (NF-κB) targeting sonosensitizer with excitation and emission wavelengths (λex/λem) of 489/628 nm, features dual</p>Formule :C62H50N4O4SCouleur et forme :SolidMasse moléculaire :947.15R-HP210
<p>R-HP210 blocks LPS-triggered IL-1β, IL-6, COX-2 gene transcription and has a 3.80 μM IC50 for NF-κB inhibition without activating GCs.</p>Formule :C22H19N3O2S2Couleur et forme :SolidMasse moléculaire :421.54Narlumosbart
CAS :<p>Narlumosbart (JMT103) is an IgG4κ monoclonal antibody that selectively binds to the receptor activator of nuclear factor-κB ligand (RANKL)[1].</p>Degré de pureté :98%Couleur et forme :Liquid(−)-N-Hydroxyapiosporamide
CAS :<p>(−)-N-Hydroxyapiosporamide (NHAP), an alkaloid, serves as an NF-κB inhibitor and demonstrates significant antitumor activity both in vitro and in vivo.</p>Formule :C24H31NO7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :445.5112-Oxo phytodienoic acid
CAS :<p>12-oxo PDA boosts alkaloid production in E. californica, enhances B. dioica tendril curls, and blocks JA-induced cell death in A. fru mutants.</p>Formule :C18H28O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :292.41OT-551 HCl
CAS :<p>OT-551 HCl is an NF-Κb inhibitor, a disubstituted hydroxylamine with antioxidant properties can be used for the treatment of cataracts and age-related macular</p>Formule :C13H24ClNO3Degré de pureté :99.71%Couleur et forme :SolidMasse moléculaire :277.79IRAK inhibitor 2
CAS :<p>IRAK inhibitor 2 (IRAK-IN-2) is a potent inhibitor of interleukin 1 receptor-associated kinase 4 (IRAK-4) for the study of inflammation-related diseases.</p>Formule :C17H14N4O2Degré de pureté :97.90% - 99.58%Couleur et forme :SolidMasse moléculaire :306.32BIZ 114
CAS :<p>BIZ 114 potently inhibits the TNF-α activated NF-κΒ pathway. BIZ 114 has the potential to prevent and/or treat ophthalmic disorders.</p>Formule :C24H40O3Couleur et forme :SolidMasse moléculaire :376.57
