NF-κB
Le facteur nucléaire kappa B (NF-κB) est un facteur de transcription qui régule l'expression des gènes impliqués dans les réponses immunitaires, l'inflammation, la survie cellulaire et la prolifération. Le NF-κB est activé en réponse à divers stimuli, y compris les cytokines, les agents pathogènes et les signaux de stress. La dérégulation de la signalisation du NF-κB est associée à des maladies inflammatoires chroniques, au cancer et aux troubles auto-immuns. Chez CymitQuimica, nous offrons une sélection complète de modulateurs de la voie NF-κB pour soutenir vos recherches en inflammation, oncologie et régulation immunitaire.
445 produits trouvés pour "NF-κB"
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Berbamine
CAS :<p>Berbamine is a natural product extracted from Phellodendron amurense.</p>Formule :C37H40N2O6Degré de pureté :98.92% - 99.67%Couleur et forme :White Crystal PowderMasse moléculaire :608.72Dauricine
CAS :<p>1.</p>Formule :C38H44N2O6Degré de pureté :99.24% - 99.75%Couleur et forme :White PowderMasse moléculaire :624.77Dendrophenol
CAS :<p>Dendrophenol (Moscatilin) is a natural product isolated from the stem of Dendrobium loddigesii Rolfe, act as a NF-κB inhibitor. Antineoplastic activity.</p>Formule :C17H20O5Degré de pureté :98.2% - 99.36%Couleur et forme :SolidMasse moléculaire :304.34SC-514
CAS :<p>SC-514 (GK 01140) is a selective, orally active, ATP-competitive IKK-2 inhibitor (IC50=11.2±4.7 μM), obstructs NF-κB-dependent gene expression.</p>Formule :C9H8N2OS2Degré de pureté :99.88% - >99.99%Couleur et forme :SolidMasse moléculaire :224.3yangonin
CAS :<p>Yangonin (Y100550) is a novel CB1 receptor ligand with affinity for human recombinant CB1 receptors.</p>Formule :C15H14O4Degré de pureté :98.82% - 99.55%Couleur et forme :Pale Yellow PowderMasse moléculaire :258.27Iron sucrose
CAS :<p>Iron sucrose (Sucroferric oxyhydroxide) is treatment of iron deficiency anemia.</p>Formule :C18H24Fe2O24Degré de pureté :99.97%Couleur et forme :SolidMasse moléculaire :736.1Neochlorogenic acid
CAS :<p>Neochlorogenic acid (trans-5-O-Caffeoylquinic acid) is an antioxidant compound used in the treatment of oxidative stress and related afflictions.</p>Formule :C16H18O9Degré de pureté :99.12% - 99.54%Couleur et forme :White PowderMasse moléculaire :354.31Triacetylresveratrol
CAS :<p>Triacetylresveratrol (Acetyl-trans-resveratrol) has anti-cancer activity, it inhibits the phosphorylation of STAT3 and NFκB in pancreatic cancer cells.</p>Formule :C20H18O6Degré de pureté :99.81%Couleur et forme :Off White PowderMasse moléculaire :354.35Micheliolide
CAS :<p>Micheliolide(MCL) is a sesquiterpene lactone which inhibits various inflammatory response.</p>Formule :C15H20O3Degré de pureté :98% - 99.37%Couleur et forme :SolidMasse moléculaire :248.32Licochalcone D
CAS :<p>Licochalcone D may treat melanoma and heart injury, halt cell spread, and reduce inflammation and allergies.</p>Formule :C21H22O5Degré de pureté :99.03% - 99.9%Couleur et forme :SolidMasse moléculaire :354.4Nitidine chloride
CAS :<p>1.</p>Formule :C21H18ClNO4Degré de pureté :96.59% - 98.91%Couleur et forme :SolidMasse moléculaire :383.82Rhoifolin
CAS :<p>Rhoifolin (Apigenin 7-O-neohesperidoside) is extracted from Turpinia arguya Seem dried leaves.</p>Formule :C27H30O14Degré de pureté :98.11% - 98.58%Couleur et forme :SolidMasse moléculaire :578.52Ginsenoside Rb1
CAS :<p>Ginsenoside Rb1 (Gypenoside Ⅲ) is part of a class of steroid glycosides; may have properties that inhibit or prevent the growth of tumors.</p>Formule :C54H92O23Degré de pureté :99.12% - 99.76%Couleur et forme :SolidMasse moléculaire :1109.29GSK481
CAS :<p>GSK481 (GSK'481) is a RIP1(Receptor Interacting Protein Kinase1) inhibitor. Inhibition of RIP1 has been shown to hinder cell necrotic death.</p>Formule :C21H19N3O4Degré de pureté :98.97%Couleur et forme :SolidMasse moléculaire :377.39Convallatoxin
CAS :<p>Convallatoxin is a natural product.</p>Formule :C29H42O10Degré de pureté :99.27% - 99.53%Couleur et forme :Prisms From Methanol + Ether SolidMasse moléculaire :550.64Cornuside
CAS :<p>Cornuside boosts immunity, reduces inflammation, protects heart and liver, and guards against brain injury by modulating stress responses.</p>Formule :C24H30O14Degré de pureté :99.86% - >99.99%Couleur et forme :SolidMasse moléculaire :542.49Bortezomib
CAS :<p>Bortezomib (LDP 341) is a 20S proteasome inhibitor (Ki=0.6 nM) that is reversible and selective.</p>Formule :C19H25BN4O4Degré de pureté :97.79% - >99.99%Couleur et forme :Yellow SolidMasse moléculaire :384.24Benzoyloxypaeoniflorin
CAS :<p>Benzoyloxypaeoniflorin, a natural compound, enhances blood flow by inhibiting platelet aggregation and coagulation.</p>Formule :C30H32O13Degré de pureté :98.52% - 99.96%Couleur et forme :SolidMasse moléculaire :600.57Pyrrolidinedithiocarbamate ammonium
CAS :<p>Pyrrolidinedithiocarbamate ammonium (1-Pyrrolidinedithiocarboxylic acid ammonium salt), a selective NF-κB inhibitor, inhibits translation of nitric oxide</p>Formule :C5H12N2S2Degré de pureté :98% - >99.99%Couleur et forme :Off-White To Pale Yellow CrystalsMasse moléculaire :164.29Sodium Aescinate
CAS :<p>Sodium Aescinate (Escin sodium salt) is extracted from Aesculus wilsonii.</p>Formule :C54H83NaO23Degré de pureté :95.17%Couleur et forme :SolidMasse moléculaire :1123.21Specnuezhenide
CAS :<p>Specnuezhenide (Nuezhenide) is isolated from the fruit of Ligustrum lucidum. It inhibits NF-κB and wnt/β-catenin signaling.Cost-effective and quality-assured.</p>Formule :C31H42O17Degré de pureté :98% - 99.93%Couleur et forme :SolidMasse moléculaire :686.66γ-Tocotrienol
CAS :<p>γ-Tocotrienol (Plastochromanol) is one of the four types of tocotrienol, a type of vitamin E.</p>Formule :C28H42O2Degré de pureté :97.27% - 98.13%Couleur et forme :SolidMasse moléculaire :410.63Ginsenoside Rk3
CAS :<p>Ginsenosides Rk3 & Rh4 may treat inflammation and ischemic heart disease.</p>Formule :C36H60O8Degré de pureté :99.33% - 99.88%Couleur et forme :SolidMasse moléculaire :620.86MLN120B
CAS :<p>MLN120B is a selective and ATP competitive IKKβ inhibitor (IC50: 60 nM).</p>Formule :C19H15ClN4O2Degré de pureté :98.92%Couleur et forme :SolidMasse moléculaire :366.8PTP1B-IN-1
CAS :<p>PTP1B-IN-1 (PTP1B inhibitor) is a potent inhibitor of protein tyrosine phosphatase 1B (PTP1B) (IC50 : 1.6 mM)</p>Formule :C8H8N2O3SDegré de pureté :99.27%Couleur et forme :SolidMasse moléculaire :212.23MD2-TLR4-IN-1
CAS :<p>MD2-TLR4-IN-1 is a myeloid differentiation protein 2/toll-like receptor 4 (MD2-TLR4) complex inhibitor.</p>Formule :C22H14Cl2N4ODegré de pureté :97.74%Couleur et forme :SolidMasse moléculaire :421.28Rubiadin-1-methyl ether
CAS :<p>Rubiadin-1-methyl ether: a natural inhibitor of bone resorption, blocking NF-κB p65 phosphorylation and IκBα degradation.</p>Formule :C16H12O4Degré de pureté :98.32%Couleur et forme :SolidMasse moléculaire :268.26Rhynchophylline
CAS :<p>Rhynchophylline (Mitrinermine) is an alkaloid isolated from Crocus sativus and is widely used in anti-inflammatory and neuroprotective studies.</p>Formule :C22H28N2O4Degré de pureté :99.44% - 99.98%Couleur et forme :Red Brown Or White Fine PowderMasse moléculaire :384.47ETHYL CAFFEATE
CAS :<p>Ethyl Caffeate (ETHYL 3,4-DIHYDROXYCINNAMATE) suppressed the differentiation of naive CD4+ T cells into Th1 in vitro.</p>Formule :C11H12O4Degré de pureté :97.79%Couleur et forme :SolidMasse moléculaire :208.21GSK583
CAS :<p>GSK583 is a highly effective and specific RIP2 kinase inhibitor (IC50: 5 nM).</p>Formule :C20H19FN4O2SDegré de pureté :98.68% - 99.81%Couleur et forme :SolidMasse moléculaire :398.45Isovitexin
CAS :<p>1.</p>Formule :C21H20O10Degré de pureté :99.79% - 99.97%Couleur et forme :SolidMasse moléculaire :432.38Denosumab
CAS :<p>Denosumab is a monoclonal antibody given subcutaneously that inhibits osteoclast activity by targeting the RANK ligand</p>Formule :C6404H9912N1724O2004S50Degré de pureté :95.9% (SDS-PAGE); 98.4% (SEC-HPLC) - 99.90%Couleur et forme :LiquidMasse moléculaire :144.71 kDaJTP 0819958 - HOIPIN-1
<p>JTP-0819958: LUBAC inhibitor, IC50 2.8 μM; blocks NF-kB activation in vitro.</p>Formule :C17H13NaO4Degré de pureté :99.95%Couleur et forme :SolidMasse moléculaire :304.27Diethylmaleate
CAS :<p>Diethylmaleate (Maleic acid, diethyl ester) is the diethyl ester of maleic acid and a glutathione-depleting compound that inhibits NF-kB.</p>Formule :C8H12O4Degré de pureté :98%Couleur et forme :Colourless LiquidMasse moléculaire :172.18Chelidonic acid
CAS :<p>Chelidonic acid, in Chelidonium majus, acts as an analgesic, antimicrobial, CNS sedative, and has anti-inflammatory properties.</p>Formule :C7H4O6Degré de pureté :99.03%Couleur et forme :SolidMasse moléculaire :184.1Ac2-26 acetate
<p>Ac2-26 acetate is an active N-terminal peptide of annexin A1(AnxA1).</p>Formule :C141H210N32O44SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :3089.43Sinomenine
CAS :<p>Sinomenine (Kukoline) is a pure alkaloid isolated from the Sinomenium acutum, is utilized in the treatment of rheumatism and arthritis.</p>Formule :C19H23NO4Degré de pureté :99.02% - 99.73%Couleur et forme :White PowderMasse moléculaire :329.39ISOGINKGETIN
CAS :<p>ISOGINKGETIN (4',4'''-Dimethylamentoflavone), a compound derived from the leaves of Ginkgo biloba, to up-regulate adiponectin secretion.</p>Formule :C32H22O10Degré de pureté :98% - 99.72%Couleur et forme :SolidMasse moléculaire :566.51AZD3264
CAS :<p>AZD3264 is a new type IKK2 inhibitor.</p>Formule :C21H23N5O4SDegré de pureté :98.98% - 99.17%Couleur et forme :SolidMasse moléculaire :441.5Astaxanthin
CAS :<p>Astaxanthin, a keto-carotenoid and xanthophyll, offers antioxidant benefits, present in red aquatic species, and used as a colorant in animal feed.</p>Formule :C40H52O4Degré de pureté :95.1% - 99.79%Couleur et forme :Needles From Acetone/Light Petroleum SolidMasse moléculaire :596.84Rocaglamide
CAS :<p>Rocaglamide (Roc-A) from Aglaia treats coughs, injuries, asthma, skin issues, and inhibits NF-κB in T-cells.</p>Formule :C29H31NO7Degré de pureté :95.32% - 99.67%Couleur et forme :SolidMasse moléculaire :505.56Curculigoside
CAS :<p>1.</p>Formule :C22H26O11Degré de pureté :99.85%Couleur et forme :SolidMasse moléculaire :466.44Ethacrynic acid
CAS :<p>Ethacrynic acid (Edecrin) 是谷胱甘肽 S-转移酶抑制剂，也是NF-κB 信号传导途径的有效抑制剂，并且还调节白三烯的形成。它还可抑制 L 型电压依赖性和储存操作的钙通道，从而导致气道平滑肌细胞松弛。它是利尿剂，具有抗炎特性，可减轻类维生素 A 诱导的小鼠耳部水肿。</p>Formule :C13H12Cl2O4Degré de pureté :98.61% - 99.85%Couleur et forme :Crystals Physical Description White Solid (Ntp 1992)Masse moléculaire :303.14Quinoclamine
CAS :<p>Quinoclamine is a naphthoquinone derivative and is an NF-κB inhibitor.</p>Formule :C10H6ClNO2Degré de pureté :99.13% - 99.28%Couleur et forme :Orange PowderMasse moléculaire :207.617,4'-Dihydroxyflavone
CAS :<p>7,4'-Dihydroxyflavone (4',7-Dihydroxyflavone) can induce transcription of nodulation (nod) genes in Rhizobium meliloti.</p>Formule :C15H10O4Degré de pureté :99.39% - 99.6%Couleur et forme :SolidMasse moléculaire :254.24Rucaparib
CAS :<p>Rucaparib (PF-01367338) is a orally PARP inhibitor and a H6PD inhibitor. Rucaparib exhibits antitumor activity against CRPC. Cost-effective and quality-assured.</p>Formule :C19H18FN3ODegré de pureté :98.24% - 99.80%Couleur et forme :SolidMasse moléculaire :323.36Geranylgeraniol
CAS :<p>Geranylgeraniol (FT0626663) is an isoprenoid found in fruits, vegetables, and grains, including rice.</p>Formule :C20H34ODegré de pureté :99.17% - ≥98%Couleur et forme :SolidMasse moléculaire :290.48Adelmidrol
CAS :<p>Adelmidrol is an anti-inflammatory ethanolamide derivative of azelaic acid.</p>Formule :C13H26N2O4Degré de pureté :99.35% - 99.73%Couleur et forme :SolidMasse moléculaire :274.36GSK2982772
CAS :<p>GSK2982772 is an inhibitor of receptor interacting serine/threonine kinase 1 (RIPK1)with IC50 values of 16 nM and 20 nM for human and monkey RIP1, respectively.</p>Formule :C20H19N5O3Degré de pureté :99.27% - 99.31%Couleur et forme :SolidMasse moléculaire :377.4IRAK inhibitor 1
CAS :<p>IRAK inhibitor 1 is an effective IRAK-4 inhibitor (IC50: 216 nM), is poorly active against JNK-1 (IC50: 3.801 μM) and JNK-2 (IC50>10 μM).</p>Formule :C17H19N5Degré de pureté :97.5% - 99.89%Couleur et forme :SolidMasse moléculaire :293.37
