NF-κB
Le facteur nucléaire kappa B (NF-κB) est un facteur de transcription qui régule l'expression des gènes impliqués dans les réponses immunitaires, l'inflammation, la survie cellulaire et la prolifération. Le NF-κB est activé en réponse à divers stimuli, y compris les cytokines, les agents pathogènes et les signaux de stress. La dérégulation de la signalisation du NF-κB est associée à des maladies inflammatoires chroniques, au cancer et aux troubles auto-immuns. Chez CymitQuimica, nous offrons une sélection complète de modulateurs de la voie NF-κB pour soutenir vos recherches en inflammation, oncologie et régulation immunitaire.
445 produits trouvés pour "NF-κB"
Trier par
Degré de pureté (%)
0
100
|
0
|
50
|
90
|
95
|
100
14-Deoxy-11,12-didehydroandrographolide
CAS :<p>14-Deoxy-11,12-didehydroandrographolide (AP10) has hypotensive, anti-inflammatory, anti-asthma, and anti-cancer actions. It can inhibit NF-κB activation.</p>Formule :C20H28O4Degré de pureté :99.13% - 99.93%Couleur et forme :SolidMasse moléculaire :332.43Rucaparib Phosphate
CAS :<p>Rucaparib Phosphate (PF-01367338 phosphate) is an inhibitor of PARP that is used in clinical therapy to sensitize cancer cells to chemotherapy.</p>Formule :C19H18FN3O·H3PO4Degré de pureté :99.37%Couleur et forme :SolidMasse moléculaire :421.36Damascenone
CAS :<p>Damascenone (trans-damascenone) is a norisoprenoid ketone mainly found in red wines. It occurs naturally in tomato and grapes.</p>Formule :C13H18ODegré de pureté :98.03%Couleur et forme :Colorless LiquidMasse moléculaire :190.28IQ-1S free acid
CAS :<p>IQ-1S free acid (IQ-1S) is an effective and specific c-Jun N-Terminal Kinase Inhibitor. IQ-1S inhibits murine delayed-type hypersensitivity.</p>Formule :C15H9N3ODegré de pureté :97.92% - 99.05%Couleur et forme :SolidMasse moléculaire :247.2520(S)-Ginsenoside Rg3
CAS :<p>20(S)-Ginsenoside Rg3 (Rg3) possess an ability to inhibit the lung metastasis of tumor cells via inhibition of the adhesion and invasion of tumor cells.</p>Formule :C42H72O13Degré de pureté :98.11% - 99.93%Couleur et forme :SolidMasse moléculaire :785.012,4-Diamino-6-hydroxypyrimidine
CAS :<p>2,4-Diamino-6-hydroxypyrimidine (DAHP) (DAHP) is a selective, specific inhibitor of GTP cyclohydrolase I, the rate limiting step for de novo pterin synthesis</p>Formule :C4H6N4ODegré de pureté :99.82%Couleur et forme :White Solid CrystalsMasse moléculaire :126.12Andrographolide
CAS :<p>Andrographolide (Andrographis)(Andrographis), an irreversible antagonist of NF-κB, has anti-inflammatory and anti-platelet aggregation activities and potential</p>Formule :C20H30O5Degré de pureté :99.39% - 99.97%Couleur et forme :PowderMasse moléculaire :350.458-Deoxygartanin
CAS :<p>8-Deoxygartanin is a butyrylcholinesterase (BChE) selective inhibitor, it exhibits significant inhibition of self-induced α2-amyloid (Aα2) aggregation, it has</p>Formule :C23H24O5Degré de pureté :99.04% - 99.88%Couleur et forme :SolidMasse moléculaire :380.43TAK-243
CAS :<p>TAK-243 (MLN7243) is a selective inhibitor of the ubiquitin-activating enzyme UAE (IC50=1 nM).</p>Formule :C19H20F3N5O5S2Degré de pureté :98.09% - 98.93%Couleur et forme :SolidMasse moléculaire :519.52Caffeic Acid Phenethyl Ester
CAS :<p>CAPE, in propolis, blocks NF-kappa B, suppresses p70S6K/Akt pathways, and inhibits PDGF, aiding in cancer protection and immune modulation.</p>Formule :C17H16O4Degré de pureté :99.18% - 99.35%Couleur et forme :Less Transparent Liquid Colorless Transparent LiquidMasse moléculaire :284.31Betulinic acid
CAS :<p>Betulinic acid, a lupane-type triterpene from white birch bark, has antiretroviral, antimalarial, anti-inflammatory, and anticancer properties.</p>Formule :C30H48O3Degré de pureté :99.12% - 99.7%Couleur et forme :White Crystalline PowderMasse moléculaire :456.7Indacaterol
CAS :<p>Indacaterol (Onbrez; Arcapta) is a β2-Adrenergic Agonist. The mechanism of action of indacaterol is as an Adrenergic beta2-Agonist.</p>Formule :C24H28N2O3Degré de pureté :99.96%Couleur et forme :SolidMasse moléculaire :392.49Rucaparib monocamsylate
CAS :<p>Rucaparib monocamsylate (Rucaparib Camsylate) is a PARP inhibitor. Rucaparib Camsylate also displays binding affinity to eight other PARP domains.</p>Formule :C29H34FN3O5SDegré de pureté :99.82%Couleur et forme :SolidMasse moléculaire :555.66Tryptanthrin
CAS :<p>Tryptanthrin is a natural DNA gyrase inhibitor.</p>Formule :C15H8N2O2Degré de pureté :99.64% - 99.94%Couleur et forme :SolidMasse moléculaire :248.24Sauchinone
CAS :<p>Sauchinone: Treats infections, prevents liver fibrosis, reduces oxidative stress, and protects skin and vascular cells.</p>Formule :C20H20O6Degré de pureté :>99.99%Couleur et forme :SolidMasse moléculaire :356.37GSK547
CAS :<p>GSK547 (GSK'547) is a highly selective and potent inhibitor of RIP1 kinase,inhibits macrophage-mediated adaptive immune tolerance in pancreatic cancer.</p>Formule :C20H18F2N6ODegré de pureté :99.17%Couleur et forme :SolidMasse moléculaire :396.39Sanggenon C
CAS :<p>Sanggenon C inhibits NF-κB activity, the expression of inducible nitric oxide synthase, tumor necrosis factor-α-stimulated cell adhesion and the expression of vascular cell adhesion molecule-1 in RAW264.7 cells. Cost-effective and quality-assured.</p>Formule :C40H36O12Degré de pureté :97.76% - 99.76%Couleur et forme :SolidMasse moléculaire :708.71HOMOPLANTAGININ
CAS :<p>Homoplantaginin is a flavonoid from a traditional Chinese medicine Salvia plebeia,it has a protective and therapeutic effect on hepatocyte injury and shows</p>Formule :C22H22O11Degré de pureté :97.63% - 99.66%Couleur et forme :SolidMasse moléculaire :462.4SC75741
CAS :<p>SC75741 is a potent P65 inhibitor with IC50 of 200 nM</p>Formule :C29H23N7O2S2Degré de pureté :99.44% - 99.54%Couleur et forme :SolidMasse moléculaire :565.67Sulforaphene
CAS :<p>Sulforaphene, from radish seeds, aids cancer cell apoptosis and inhibits migration; has an ED50 for velvetleaf at ~2x10^-4 M.</p>Formule :C6H9NOS2Degré de pureté :97.55% - 99.19%Couleur et forme :Slightly Yellowish LiquidMasse moléculaire :175.27Ginsenoside Rg5
CAS :<p>Ginsenoside Rg5 shows promise for Alzheimer's, reduces inflammation, and aids vascular health without side effects.</p>Formule :C42H70O12Degré de pureté :98% - 99.65%Couleur et forme :SolidMasse moléculaire :767WAY-169916
CAS :<p>WAY-169916 inhibits ER by blocking NF-kB activity, lacks estrogenic effects.</p>Formule :C17H13F3N2O2Degré de pureté :98.63% - 98.64%Couleur et forme :SolidMasse moléculaire :334.29Astilbin
CAS :<p>Astilbin (Neoastilbin) is actions Flavonoid phytochemical found in St. John′s wort and Traditional Chinese Medicine herbal preparations.</p>Formule :C21H22O11Degré de pureté :97% - 99.86%Couleur et forme :White PowderMasse moléculaire :450.39Praeruptorin A
CAS :<p>Praeruptorin A ((+)-Praeruptorin A) has the potential to inhibit migration/fusion of preosteoclasts in vitro and bone erosion in vivo by targeting calmodulin</p>Formule :C21H22O7Degré de pureté :99.63% - 99.65%Couleur et forme :SolidMasse moléculaire :386.4Tenuigenin
CAS :<p>Tenuigenin (Senegenin) is a natural product from Polygala tenuifolia used in Chinese medicine with antioxidative and anti-inflammatory activity.</p>Formule :C30H45ClO6Degré de pureté :98.9% - 99.53%Couleur et forme :SolidMasse moléculaire :537.13Tectochrysin
CAS :<p>Tectochrysin: antioxidant, hinders ABCG2 transport, induces apoptosis in NSC-LC by blocking STAT3 and activating DR3/Fas.</p>Formule :C16H12O4Degré de pureté :99.26%Couleur et forme :SolidMasse moléculaire :268.26INH14
CAS :<p>INH14 is a novel inhibitor of the IKKα/β-dependent TLR inflammatory response (IC50s: 8.97/3.59 μM for IKKα/IKKβ).</p>Formule :C15H16N2ODegré de pureté :95.41%Couleur et forme :SolidMasse moléculaire :240.3Picroside II
CAS :<p>Picroside II (Vanilloyl catalpol) is the main active ingredient in iridoid glycosides.</p>Formule :C23H28O13Degré de pureté :98% - 99.83%Couleur et forme :SolidMasse moléculaire :512.46Phorbol 12-myristate 13-acetate
CAS :<p>Phorbol 12-myristate 13-acetate (PMA) belongs to the phorbol ester group of natural products and is an activator of PKC, SphK, and NF-κB.</p>Formule :C36H56O8Degré de pureté :98.55% - >99.99%Couleur et forme :White To Off-White SolidMasse moléculaire :616.83Handelin
CAS :<p>Handelin has anti-inflammatory activity by inhibiting NF-κB activation and pro-inflammatory cytokine productions.</p>Formule :C32H40O8Degré de pureté :99.02% - 99.345%Couleur et forme :SolidMasse moléculaire :552.66Sciadopitysin
CAS :<p>Sciadopitysin may thwart diabetic bone disease, boost mitochondria, protect osteoblasts, and hinder Aβ aggregation/neurotoxicity.</p>Formule :C33H24O10Degré de pureté :98.14% - 99.17%Couleur et forme :SolidMasse moléculaire :580.54HS-1371
CAS :<p>HS-1371 is a novel kinase inhibitor of receptor-interacting protein kinase 3 (RIP3) with an IC50 of 20.8 nM.</p>Formule :C24H24N4ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :384.47Okanin
CAS :<p>Okanin shows significant activities on both linoleic acid peroxidation inhibition and DPPH radical scavenging effect.</p>Formule :C15H12O6Degré de pureté :95.19% - 99.4%Couleur et forme :SolidMasse moléculaire :288.25Schisantherin A
CAS :<p>Schisantherin A, a lignan from Schisandra fruit, is used as an antitussive, tonic, and sedative.</p>Formule :C30H32O9Degré de pureté :98% - 99.989Couleur et forme :SolidMasse moléculaire :536.57Necrostatin 2 racemate
CAS :<p>Necrostatin 2 racemate (Necrostatin-2 racemate) is an potent and specific inhibitor of RIPK1.</p>Formule :C13H12ClN3O2Degré de pureté :98% - 99.5%Couleur et forme :SolidMasse moléculaire :277.71Esculentoside H
CAS :<p>Phytolaccaceae has anti-tumor activity, the mechanism may be related to the capacity of Esculentoside H for TNF release.</p>Formule :C48H76O21Degré de pureté :98.04% - 99.3%Couleur et forme :SolidMasse moléculaire :989.1Isoliquiritin apioside
CAS :<p>Isoliquiritin apioside, from Glycyrrhizae radix, inhibits MMP9, MAPK, NF-κB, reduces cancer cell invasion, angiogenesis, and fights oxidative DNA damage.</p>Formule :C26H30O13Degré de pureté :98.84% - 99.27%Couleur et forme :SolidMasse moléculaire :550.51Ginsenoside Re
CAS :<p>Ginsenoside Re (Ginsenoside B2) may have properties that inhibit or prevent the growth of tumors.</p>Formule :C48H82O18Degré de pureté :99.12% - >99.99%Couleur et forme :White PowderMasse moléculaire :947.15Suberosin
CAS :<p>Suberosin: anti-inflammatory, anticoagulant, deters Aedes aegypti bites, potential mosquito larvicide.</p>Formule :C15H16O3Degré de pureté :97.08% - 99.26%Couleur et forme :SolidMasse moléculaire :244.29NDMC101
CAS :<p>NDMC101 suppresses dipeptidyl peptidase-IV, NFATc1, and NF-κB in human T cells, modulating immunity.</p>Formule :C13H9ClFNO2Degré de pureté :99.89%Couleur et forme :SolidMasse moléculaire :265.67IRAK4-IN-1
CAS :<p>IRAK4-IN-1 is an interleukin-1 receptor associated kinase 4 (IRAK4) inhibitor with an IC50 of 7 nM.</p>Formule :C19H23N5ODegré de pureté :98.18% - 99.85%Couleur et forme :SolidMasse moléculaire :337.42BMS-345541 hydrochloride
CAS :<p>BMS-345541 hydrochloride is a selective IKK inhibitor (IKK2 and IKK1 with IC50 of 0.3 μM and 4 μM,respectively).</p>Formule :C14H18ClN5Degré de pureté :99.13%Couleur et forme :SolidMasse moléculaire :291.78IKK 16
CAS :<p>IKK 16 (IKK Inhibitor VII) is a selective IκB kinase (IKK) inhibitor for IKK-2, IKK complex and IKK-1 with IC50 of 40 nM, 70 nM and 200 nM, respectively.</p>Formule :C28H29N5OSDegré de pureté :98.76% - 99.61%Couleur et forme :SolidMasse moléculaire :483.63GSK2983559 active metabolite
CAS :<p>GSK2983559 active metabolite (RIPK2-IN-1) is a potent, selective receptor-interacting protein-2 (RIP2) kinase inhibitor.</p>Formule :C21H22N4O4S2Degré de pureté :97.07% - 99.57%Couleur et forme :SolidMasse moléculaire :458.55NF-κΒ activator 2
CAS :<p>NF-κΒ Activator 2 is a potent, orally active compound that efficiently activates NF-κB with an EC50 value of 1.58 μM.</p>Formule :C16H11FN2O3Degré de pureté :98.12%Couleur et forme :SolidMasse moléculaire :298.27Eurycomalactone
CAS :<p>Eurycomalactone, from Eurycoma longifolia, inhibits NF-κB (IC50 0.5 μM), stops protein synthesis and cyclin D1, spares IκBα and IKK.</p>Formule :C19H24O6Degré de pureté :99.48% - 99.87%Couleur et forme :SolidMasse moléculaire :348.39JSH-23
CAS :<p>JSH-23 is an NF-κB inhibitor that inhibits NF-κB transcriptional activity without affecting IκB degradation. JSH-23 is an antioxidant. Cost effective and quality assured.</p>Formule :C16H20N2Degré de pureté :98.03% - 99.67%Couleur et forme :SolidMasse moléculaire :240.34GS143
CAS :<p>GS143 inhibits IκBα ubiquitination (IC50=5.2μM), suppresses NF-κB, and has anti-asthma properties without hindering proteasomes.</p>Formule :C28H19FN2O4Degré de pureté :97.67%Couleur et forme :SolidMasse moléculaire :466.46Isodeoxyelephantopin
CAS :<p>Isodeoxyelephantopin can inhibit the growth of various tumor cells.</p>Formule :C19H20O6Degré de pureté :99.88%Couleur et forme :SolidMasse moléculaire :344.36IKKγ NBD Inhibitory Peptide acetate
<p>IKKγ NBD Inhibitory Peptide acetate is a NEMO-binding domain peptide (NBD peptide) acetate corresponding to the NEMO amino-terminal alpha-helical region.</p>Degré de pureté :99.15%Couleur et forme :SolidMasse moléculaire :N/A
