CXCR
Les CXCR sont une sous-famille de GPCR qui se lient aux chimiokines, de petites protéines de signalisation qui guident le déplacement des cellules immunitaires vers les sites d'inflammation, d'infection ou de lésion. Les CXCR jouent des rôles cruciaux dans les réponses immunitaires, la métastase du cancer et les maladies inflammatoires. Les modulateurs des CXCR sont étudiés pour leur potentiel dans le traitement des maladies auto-immunes, du cancer et des affections inflammatoires chroniques. Chez CymitQuimica, nous offrons une gamme de modulateurs de CXCR de haute qualité pour soutenir vos recherches en immunologie, oncologie et inflammation.
158 produits trouvés pour "CXCR"
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ITIC
CAS :"ITIC, a non-fullerene acceptor with high Tg of 180°C, shows excellent thermal stability and a low glass-crystal transition, plus unique crystallization."Formule :C94H82N4O2S4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1427.96CXCR7 modulator 1
CAS :CXCR7 modulator 1 is an effective and orally bioavailable peptoid hybrid CXCR7 modulator with Ki of 9 nM.Formule :C48H57F2N7O7SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :914.07CTCE-9908
CAS :CXCR4 blocker; triggers cell division failure in ovarian cancer, boosts taxol and docetaxel treatment effects, proven in mice.Formule :C86H147N27O23Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1927.27RCP168
RCP168 is a highly selective and potent CXCR4 receptor antagonist with an IC50 of 5 nM. It exhibits superior capacity to inhibit HIV-1 (Human Immunodeficiency Virus type 1) from entering host cells via the CXCR4 receptor compared to natural chemokines. RCP168 suppresses HIV-1 infection by blocking viral binding sites or inducing receptor internalization. It can be utilized in research to study interactions between the CXCR4 receptor and other chemokine receptors.Formule :C365H585N105O95S5Masse moléculaire :8119.27766PDE4D inhibitor 1
PDE4-IN-1 is a PDE4 inhibitor characterized by high potency (IC50: 8.6 nM) and superior selectivity over other PDE subtypes. This compound inhibits the release of inflammatory cytokines and chemokines. Additionally, PDE4-IN-1 significantly restores the damaged cAMP-CREB signaling pathway, inhibits proliferation, and promotes differentiation to reverse psoriasis formation.Couleur et forme :Odour SolidBVT173187
CAS :BVT173187 is a neutrophil formyl peptide receptors (FPR1) inhibitor.Formule :C14H10Cl3NO2Couleur et forme :SolidMasse moléculaire :330.59CXCR4 antagonist 2
CAS :CXCR4 antagonist 2 is a CXCR4 antagonist with an IC 50 value of 47 nM.Formule :C25H36N6Couleur et forme :SolidMasse moléculaire :420.605PS372424 hydrochloride
CAS :PS372424 hydrochloride,CXCR3 agonist. Anti-inflammatory. Inhibits T-cell migration.Formule :C33H45ClN6O4Degré de pureté :95.03%Couleur et forme :SolidMasse moléculaire :625.2ACT-1004-1239
CAS :ACT-1004-1239 is a CXCR7 antagonist with immunomodulatory and myelination-promoting effects, used for research on inflammatory demyelinating diseases.
Formule :C27H28F2N6O3Degré de pureté :98.31%Couleur et forme :SolidMasse moléculaire :522.55ATI-2341
CAS :ATI-2341, pepducin targeting the CXCR4, is an allosteric agonist activating the Gi to promote inhibition of cAMP production and induce calcium mobilization.Formule :C104H178N26O25S2Couleur et forme :SolidMasse moléculaire :2256.82CXCR2 antagonist 8
CAS :CXCR2 antagonist 8 is a selective CXCR2 antagonist, which can be used for the treatment and prevention of insulin resistance.Formule :C14H13N3O5Couleur et forme :SolidMasse moléculaire :303.27LY2510924
CAS :LY2510924 is an effective and selective CXCR4 antagonist. It blocks SDF-1 binding to CXCR4 (IC50: 0.079 nM).Formule :C62H88N14O10Couleur et forme :SolidMasse moléculaire :1189.45Motixafortide
CAS :Motixafortide (BKT140 4-fluorobenzoyl) is an antagonist of CXCR4 (IC50: 1 nM).Formule :C97H144FN33O19S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :2159.52Peptide R TFA
Peptide R (TFA) is a synthetic and specific CXCR4 antagonist. It demonstrates excellent tumor stroma remodeling capabilities and is applicable in research on solid tumors, such as glioblastoma.Formule :C39H57N13O8S2·xC2HF3O2Couleur et forme :SolidMasse moléculaire :900.08 (free base)Navarixin
CAS :Navarixin (MK-7123)(SCH527123) is a novel, selective CXC chemokine receptor 2(CXCR2) antagonist that inhibits neutrophil activation and modulates neutrophilFormule :C21H23N3O5Degré de pureté :98% - 99.51%Couleur et forme :SolidMasse moléculaire :397.42Ref: TM-T7130
1mg38,00€5mg80,00€10mg114,00€25mg200,00€50mg299,00€100mg442,00€500mg973,00€1mL*10mM (DMSO)88,00€ML339
CAS :ML339 a selective inhibitor of CXCR6(IC50 = 140 nM) with no response when screened against CXCR5 and CXCR4.Formule :C26H32ClN3O5Degré de pureté :99.9%Couleur et forme :SolidMasse moléculaire :502WZ811
CAS :WZ811 is a novel and effective small molecular CXCR4 antagonist (EC50: 0.3 nM).Formule :C18H18N4Degré de pureté :99.42% - ≥95%Couleur et forme :SolidMasse moléculaire :290.36AMD-070 hydrochloride
CAS :AMD-070 hydrochloride is a CXCR4 antagonist, is useful for Anti HIV.Formule :C21H28ClN5Degré de pureté :98.38% - 98.57%Couleur et forme :SolidMasse moléculaire :385.93JMS-17-2 hydrochloride
CAS :JMS-17-2 hydrochloride: potent CX3CR1 blocker, IC50 of 0.32 nM, hinders breast cancer metastasis.Formule :C25H27Cl2N3OCouleur et forme :SolidMasse moléculaire :456.41USL311
CAS :USL311 blocks CXCR4/SDF-1 interaction, inhibits tumor cell growth and migration.Formule :C24H34N6ODegré de pureté :98.46% - 99.56%Couleur et forme :SolidMasse moléculaire :422.57Ref: TM-T17208
1mg42,00€5mg88,00€10mg127,00€25mg250,00€50mg393,00€100mg628,00€500mg1.304,00€1mL*10mM (DMSO)87,00€
