TLR
Les récepteurs de type Toll (TLR) sont une classe de protéines qui jouent un rôle crucial dans le système immunitaire inné en reconnaissant les motifs moléculaires associés aux pathogènes (PAMP) et en initiant des réponses immunitaires. Les TLR sont impliqués dans la détection d'une large gamme de pathogènes, y compris les bactéries, les virus et les champignons, et sont essentiels pour l'activation des voies de signalisation inflammatoires. La dérégulation de la signalisation des TLR est associée à des maladies inflammatoires chroniques, des troubles auto-immuns et le cancer. Chez CymitQuimica, nous offrons une variété de modulateurs TLR de haute qualité pour soutenir vos recherches sur l'immunité innée, l'inflammation et les maladies infectieuses.
74 produits trouvés pour "TLR"
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BMS-905
CAS :BMS-905 is a potent dual inhibitors of TLR7 and TLR8 with good selectivity against TLR9 and other family members.Formule :C23H29N3Degré de pureté :99.94%Couleur et forme :SoildMasse moléculaire :347.5CU-T12-9
CAS :CU-T12-9 is a potent TLR1/2 agonist(EC50 of 52.9 nM in HEK-Blue hTLR2 SEAP assay).Formule :C17H13F3N4O2Degré de pureté :99.84%Couleur et forme :SolidMasse moléculaire :362.31Ref: TM-T15017
1mg50,00€5mg105,00€10mg160,00€25mg268,00€50mg409,00€100mg583,00€1mL*10mM (DMSO)117,00€CU-CPT17e
CAS :CU-CPT17e is a potent agonist of TLR(TLR3, TLR8, and TLR9).Formule :C27H24N2O8Degré de pureté :98.49%Couleur et forme :SolidMasse moléculaire :504.49CU-CPT22
CAS :CU-CPT22: first TLR1/2 complex probe, binds at TLR1/2 interface (IC50=0.58μM), inhibits Pam3CSK4 binding (Ki=0.41μM).Formule :C19H22O7Degré de pureté :98.66% - 99.80%Couleur et forme :SolidMasse moléculaire :362.37Ref: TM-T15020
1mg49,00€2mg66,00€5mg94,00€10mg159,00€25mg296,00€50mg444,00€100mg647,00€200mg888,00€1mL*10mM (DMSO)108,00€IAXO-102
CAS :IAXO-102 is a TLR4 antagonist that negatively regulates TLR4 signaling.Formule :C35H71NO5Degré de pureté :98.17%Couleur et forme :SolidMasse moléculaire :585.94TLR7/8 agonist 3
CAS :TLR7/8 agonist 3 is a potent agonist of TLR7 and TLR8.Formule :C17H23N5ODegré de pureté :99.84%Couleur et forme :SolidMasse moléculaire :313.4Ref: TM-T13167
1mg60,00€5mg133,00€10mg215,00€25mg349,00€50mg482,00€100mg665,00€200mg893,00€1mL*10mM (DMSO)147,00€ODN 4084-F
CAS :ODN 4084-F, a class B ('broadly-active') inhibitory ODN, is a potent inhibitor of TLR9-induced B cells and macrophages.Couleur et forme :SolidCU-115
CAS :CU-115 is a selective and potent TLR8 antagonist with IC50 of 1.04 µM and =>50 µM for TLR8 and TLR7, respectively.
Formule :C21H11F7INO2Degré de pureté :99.96%Couleur et forme :SolidMasse moléculaire :569.21Pam3CSK4-Biotin
CAS :Pam3CSK4-Biotin is a biotinylated derivative of Pam3CSK4, functioning as a Toll-like receptor 1/2 (TLR1/2) agonist.Formule :C103H192N14O17S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1962.85Pam2CSK4
CAS :TLR2/6 agonist; boosts TNF-α in human cells & mouse B cell growth/activation.Formule :C65H126N10O12SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :1271.83Atibuclimab
CAS :Atibuclimab is a chimeric monoclonal antibody targeting CD14, consisting of a mouse variable region and a human IgG4 Fc region.Degré de pureté :> 95% - > 95%Couleur et forme :LiquidMasse moléculaire :145.28 kDaCRX 527
CAS :CRX 527 is a TLR4 ligand and serves as an adjuvant for peptide cancer vaccines, enhancing anti-tumor immune responses. CRX 527 also induces hematopoietic stem cell (HSC) differentiation, increasing the proportion and number of LSK cells, and promotes their differentiation into macrophages. This activation bolsters immune defense and protects intestinal epithelium from radiation damage.Formule :C81H151N2O19PCouleur et forme :SolidMasse moléculaire :1488.04MTvkPABC-P5 TFA
MTvkPABC-P5d TFA, a TLR7 agonist, functions as an immune stimulant. It is applicable in the synthesis of immune-stimulating antibody conjugates (ISAC).Couleur et forme :Odour SolidRKH acetate
RKH acetate offers protective effects against mortality and organ damage caused by sepsis. It can directly bind to Toll-like receptor 4 (TLR4) and inhibit TLR4 signaling in immune cells.Formule :C18H33N9O4·xC2H4O2TLR7/8 agonist 12
TLR7/8 agonist 12 (compound 9) is a human TLR7/8 agonist with EC50 values of 11 nM for hTLR7 and 150 nM for hTLR8, indicating its potential for immune modulation.
Formule :C29H38N6O3Couleur et forme :SolidMasse moléculaire :518.65MC-Val-Cit-PAB-Amide-TLR7 agonist 4 TFA
MC-Val-Cit-PAB-Amide-TLR7 agonist 4 TFA is the trifluoroacetate form of MC-Val-Cit-PAB-Amide-TLR7 agonist 4,a HER2-TLR7 and HER2- TLR8 immune agonist complexes.Formule :C54H73F3N12O13Degré de pureté :99.67%Couleur et forme :SolidMasse moléculaire :1155.22Ref: TM-T74468L
1mg190,00€5mg471,00€10mg663,00€25mg1.036,00€50mg1.429,00€100mg1.830,00€200mg2.498,00€IPH33
IPH33 is a human monoclonal antibody (mAb) targeting TLR3/CD283. It is useful for research in cancer and inflammation.Couleur et forme :Odour LiquidRKH
PKH is a TLR4 antagonist, and it is a new tripeptide derived from Akkermansia muciniphila. PKH reduces inflammation-related cell activation and the overproduction of pro-inflammatory factors induced by sepsis.Formule :C18H33N9O4Masse moléculaire :439.26555L07-2
CAS :L07-2 (Compound 6) is an active scaffold that includes a TLR7/8 agonist. It is suitable for the synthesis of immune-stimulating antibody conjugates (ISACs) used in cancer research.Formule :C56H83N15O14Couleur et forme :SolidMasse moléculaire :1190.35Tilsotolimod sodium
CAS :Tilsotolimod sodium, a synthetic Toll-like receptor 9 (TLR9) agonist, has shown antitumor activity in preclinical models.Formule :C223H262N74Na22O115P22S22Couleur et forme :SolidMasse moléculaire :7711.51PVP-037.2
CAS :PVP-037.2 is a TLR7/8 agonist that acts as an adjuvant to enhance vaccine-induced TH1 immune responses and boost the production of antigen-specific antibodies IgG1 and IgG2c.Formule :C23H20F3N5OCouleur et forme :SoildMasse moléculaire :439.43(R)-Thalidomide-pyrrolidine-C-piperidine-Ph-NH2
(R)-Thalidomide-pyrrolidine-C-piperidine-Ph-NH2 serves as the E3 ubiquitin ligase ligand and linker for PROTAC(R)-NX-2127, utilized in cancer research.Formule :C29H33N5O4Couleur et forme :SolidMasse moléculaire :515.6Ezeprogind
CAS :Ezeprogind, TLR9 inhibitor for Alzheimer's. Affordable Excellence: Reliable Quality You Can TrustFormule :C25H44N6Degré de pureté :99.28%Couleur et forme :SolidMasse moléculaire :428.66TLR8 agonist 8
CAS :TLR8 agonist8 (Compound II-72) is an agonist of Toll-like receptor 8 (TLR8) with an EC50 of 0.25-1 μM. It demonstrates stability in both human and mouse plasma and induces the secretion of the cytokine TNFα with an EC50 of less than 1 μM. In the MC38-HER2 xenograft mouse model, TLR8 agonist8 exhibits antitumor activity, achieving a tumor growth inhibition (TGI) rate of 89%.Formule :C53H63N11O10Couleur et forme :SolidMasse moléculaire :1014.14TLR8 agonist 7
CAS :TLR8 agonist7 is an agonist of Toll-like receptor 8 (TLR8) with an EC50 of less than 250 nM. It remains stable in human and mouse plasma and induces the secretion of the cytokine TNFα with an EC50 of less than 1 μM. In the MC38-HER2 xenograft mouse model, TLR8 agonist7 demonstrates antitumor activity, achieving a tumor growth inhibition (TGI) rate of 98%.Formule :C54H63N9O16Couleur et forme :SolidMasse moléculaire :1094.13TLR7 agonist 17
CAS :TLR7 agonist 17 (compound 20) functions as a highly effective TLR7 agonist, exhibiting EC 50 values of 12 nM for hTLR7 and 17 nM for mTLR7. Additionally, this compound has demonstrated anticancer activity [1].Formule :C25H37N7O3Couleur et forme :SolidMasse moléculaire :483.61TLR7 agonist 24
TLR7 agonist24 (Compound 21) is an agonist of TLR7 with an EC50 of 3.72 μM. When combined with Aluminum Hydroxide, it can be employed as a vaccine adjuvant to enhance the immune response to antigens from SARS-CoV-2 and hepatitis B.Couleur et forme :Odour SolidPam3CSK4
CAS :Pam3CSK4 is a synthetic triacylated lipopeptide (LP) that mimics the acylated amino terminus of bacterial LPs.Formule :C81H156N10O13SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :1510.23TLR7 agonist 3
CAS :TLR7 agonist 3 is a Toll-like receptor 7 (TLR7) agonist that has anticancer activity and is used in the study of diseases of the immune system.
Formule :C18H24N4ODegré de pureté :99.27%Couleur et forme :SolidMasse moléculaire :312.41Toll-like receptor modulator
CAS :Toll-like receptor modulator is a TLR7/8 modulator, which modulates immune function.Formule :C15H13F5N2O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :348.27Neoseptin-3
CAS :Neoseptin-3 is a novel small molecule agonist of mouse mTLR4/MD2 with EC50=18.5 μM that does not activate human TLR4/MD2.Formule :C29H34N2O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :474.59Motolimod
CAS :Motolimod (VTX-378) (VTX-2337) is an effective and specific Toll-like receptor (TLR) 8 agonist (EC50: 100 nM), > 50-fold selectivity over TLR7.Formule :C28H34N4O2Degré de pureté :97.43% - 99.66%Couleur et forme :SolidMasse moléculaire :458.6TLR7 agonist 2
CAS :TLR7 agonist 2 (TLR7-IN-1) is a specific and effective Toll-like Receptor 7 (TLR7) agonist (LEC=0.4 μM).
Formule :C17H16N6O2Degré de pureté :99.33%Couleur et forme :SolidMasse moléculaire :336.35TLR7/8 agonist 1
CAS :TLR7/8 agonist 1 is a toll-like receptor TLR7/TLR8 agonist with anticancer and antiviral activities and can be used to study immune-related diseases.Formule :C22H25N5Degré de pureté :99.4%Couleur et forme :SolidMasse moléculaire :359.47Telratolimod
CAS :Telratolimod (MEDI9197) is a toll-like receptors 7/8 agonist. It has an antitumor activity.Formule :C36H59N5O2Degré de pureté :98.61%Couleur et forme :SolidMasse moléculaire :593.89Enpatoran
CAS :Enpatoran is an inhibitor of TLR7(IC50 = 11.1 nM) and TLR8(IC50 = 24.1 nM).Formule :C16H15F3N4Degré de pureté :97.08% - 99.38%Couleur et forme :SolidMasse moléculaire :320.31Ref: TM-T9570
1mg113,00€5mg222,00€10mg334,00€25mg552,00€50mg782,00€100mg1.054,00€200mg1.414,00€1mL*10mM (DMSO)161,00€CU-CPT-8m
CAS :CU-CPT-8m (TLR8-specific antagonist) is an toll-like receptor 8 (TLR8) antagonist (IC50 : 67 nM)Formule :C14H12N4ODegré de pureté :99.00%Couleur et forme :SolidMasse moléculaire :252.27SM-324405
CAS :SM-324405 is an agonist of TLR7.Formule :C19H23N5O4Degré de pureté :97.83%Couleur et forme :SolidMasse moléculaire :385.42Ref: TM-T7860
2mg34,00€5mg52,00€10mg84,00€25mg138,00€50mg215,00€100mg306,00€200mg427,00€1mL*10mM (DMSO)57,00€CU-CPT9b
CAS :CU-CPT9b (TLR8-specific antagonist 1) is an antagonist of toll-like receptor 8 (TLR8; Kd = 21 nM).Formule :C16H13NO2Degré de pureté :98.1%Couleur et forme :SolidMasse moléculaire :251.28Ref: TM-T7302
1mg49,00€5mg92,00€10mg152,00€25mg245,00€50mg340,00€100mg504,00€200mg717,00€1mL*10mM (DMSO)105,00€MD2-IN-1
CAS :MD2-IN-1 is a Myeloid differentiation protein 2 (MD2) inhibitor with a KD of 189 μM for the recombinant human MD2 (rhMD2).Formule :C20H22O6Degré de pureté :99.87%Couleur et forme :SolidMasse moléculaire :358.39C29
CAS :C29 inhibits TLR2/1 and TLR2/6 in human cells, but only TLR2/1 in mouse macrophages.Formule :C16H15NO4Degré de pureté :96.34% - 97.37%Couleur et forme :SolidMasse moléculaire :285.29TLR3-IN-1
CAS :TLR3-IN-1 (CU CPT 4a) is a selective TLR3 inhibitor. It can inhibit TLR3/dsRNA complex-mediated downstream signaling pathways and inhibit the TNF-α and IL-1β.Formule :C18H13ClFNO3SDegré de pureté :98.56%Couleur et forme :SolidMasse moléculaire :377.82Ref: TM-T22698
1mg52,00€5mg103,00€10mg168,00€25mg353,00€50mg504,00€100mg708,00€1mL*10mM (DMSO)113,00€RS09 2TFA (1449566-36-2 free base)
RS09 2TFA is a TLR4 agonist enhancing NF-κB and cytokines in macrophages; it's an adjuvant that boosts X-15 antibodies.Formule :C35H51F6N9O13Degré de pureté :>99.99%Couleur et forme :SolidMasse moléculaire :919.82CU-CPT-9a
CAS :CU-CPT-9a is a potent TLR8 inhibitor (IC50 : 0.5 nM), that suppresses TLR8-mediated proinflammatory signaling in various cell lines and human primary cells-Formule :C17H15NO2Degré de pureté :99.01%Couleur et forme :SolidMasse moléculaire :265.31Ref: TM-T7317
1mg38,00€2mg50,00€5mg84,00€10mg119,00€25mg225,00€50mg409,00€100mg605,00€1mL*10mM (DMSO)93,00€TLR7/8/9-IN-1
CAS :TLR7/8/9-IN-1 is a potent inhibitor of Toll-like receptors 7/8/9 (TLR7/8/9) with an IC50 of 43 nM.Formule :C27H37N3O2Degré de pureté :99.56%Couleur et forme :SolidMasse moléculaire :435.6Ref: TM-T39669
1mg49,00€2mg70,00€5mg111,00€10mg178,00€25mg290,00€50mg424,00€100mg577,00€200mg825,00€1mL*10mM (DMSO)166,00€Pam3CSK4 TFA (112208-00-1 free base)
CAS :Pam3CSK4 TFA (Pam3Cys-Ser-(Lys)4 TFA) is a Toll-like receptor 1/2 agonist with EC50 of 0.47 ng/mL for human TLR1/2.Cost-effective and quality-assured.
Formule :C87H159F9N10O19SDegré de pureté :96.4% - 99.01%Couleur et forme :SolidMasse moléculaire :1852.33TLR4-IN-C34
CAS :TLR4-IN-C34 is an inhibitor of TLR4, and reduces systemic inflammation in models of endotoxemia and necrotizing enterocolitisFormule :C17H27NO9Degré de pureté :99.69%Couleur et forme :SolidMasse moléculaire :389.4Bropirimine
CAS :Bropirimine (U-54461) (U-54461) is a biological response modifier that is thought to act through the induction of lymphokines.Formule :C10H8BrN3ODegré de pureté :99.01%Couleur et forme :SolidMasse moléculaire :266.091V209
CAS :1V209 (TLR7 agonist T7) is a Toll-like receptor 7 (TLR7) agonist and has anti-tumor effects.Formule :C16H17N5O5Degré de pureté :99.61%Couleur et forme :SolidMasse moléculaire :359.34TLR7/8 agonist 1 dihydrochloride
CAS :TLR7/8 agonist 1 dihydrochloride (TLR7/8 agonist-5d) is a TLR7/8 agonist which shows prominent immunostimulatory activities.Formule :C22H27Cl2N5Degré de pureté :98.33%Couleur et forme :SolidMasse moléculaire :432.39Ref: TM-T5561
1mg57,00€5mg120,00€10mg187,00€25mg406,00€50mg630,00€100mg898,00€200mg1.216,00€1mL*10mM (DMSO)133,00€Robinin
CAS :Robinin: a kaempferol-derived flavone glycoside with antibacterial, diuretic traits; minimal effect on Colo 320 MDR1/LRP resistance; detected in MCF-7 cells.Formule :C33H40O19Degré de pureté :98.78% - 99.13%Couleur et forme :SolidMasse moléculaire :740.66Paridiprubart
CAS :Paridiprubart (NI-0101) is a humanised monoclonal antibody targeting TLR4, ameliorative effects in COVID-19 patients with ARDS and rheumatoid arthritis.Degré de pureté :95% - 96.9% (SDS-PAGE); 98.5% (SEC-HPLC)Couleur et forme :LiquidMasse moléculaire :145.16 kDaTLR7 agonist 1
CAS :TLR7 agonist 1 is a selective and oral TLR7 agonist (IC50: 90 nM).Formule :C21H25N5ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :363.46AXC-715 trihydrochloride
CAS :AXC-715 trihydrochloride is a TLR7/8 agonist used to make PD-L1 adjuvanted antibody immunocouplings.Formule :C18H28Cl3N5Degré de pureté :99.87%Couleur et forme :SolidMasse moléculaire :420.81CL264
CAS :CL264, a selective agonist of TLR7, can be used in studies about innate immune signals.Formule :C19H23N7O4Degré de pureté :98.01% - 99.87%Couleur et forme :SolidMasse moléculaire :413.43Ref: TM-T10833
1mg49,00€5mg110,00€10mg182,00€25mg289,00€50mg399,00€100mg530,00€200mg715,00€1mL*10mM (DMSO)122,00€DSR-6434
CAS :DSR-6434 is a selective agonist of TLR7 with antitumor effect. DSR-6434 exhibits EC50s of 7.2 nM and 4.6 nM for human and mouse.Formule :C19H28N8O2Degré de pureté :99.78%Couleur et forme :SolidMasse moléculaire :400.48AZD8848
CAS :AZD8848 is a selective antedrug agonist of toll-like receptor 7 (TLR7). It is developed for the research of asthma and allergic rhinitis.Formule :C29H43N7O5Couleur et forme :SolidMasse moléculaire :569.7TLR7/8-IN-1
CAS :TLR7/8-IN-1, a crystalline TLR7/TLR8 inhibitor, is a valuable compound for autoimmune disease research.Cost-effective and quality-assured.Formule :C29H40N8O2Degré de pureté :99.99%Couleur et forme :SolidMasse moléculaire :532.68M62812
CAS :TLR4 inhibitor blocks LPS-induced NF-κB (IC50=2.4μg/mL), cytokines in PBMCs/HUVECs, and extends life in septic shock mice.Formule :C13H13Cl2N3OSDegré de pureté :99.07%Couleur et forme :SolidMasse moléculaire :330.23AT791
CAS :AT791 is an orally available TLR7 and TLR9 inhibitor, suppressing TLR7 and TLR9 signaling, used in autoimmune lupus research.Formule :C23H31N3O3Degré de pureté :99.88%Couleur et forme :SolidMasse moléculaire :397.51Ref: TM-T61882
1mg69,00€5mg147,00€10mg224,00€25mg358,00€50mg512,00€100mg707,00€200mg982,00€1mL*10mM (DMSO)164,00€BBIQ
CAS :BBIQ is a powerful vaccine adjuvant that enhances innate immune responses and a potent and selectively toll-like receptor 7 (TLR7) agonist with an EC50 of 59.1Formule :C21H22N4Degré de pureté :99.71%Couleur et forme :SolidMasse moléculaire :330.43SM360320
CAS :SM360320 (CL-087) is a selective TLR7 agonist that blocks HCV replication in hepatocytes and aids immunology research.
Formule :C15H17N5O3Degré de pureté :99.13%Couleur et forme :SolidMasse moléculaire :315.33Rabeximod
CAS :Rabeximod, an immunomodulator, eases autoimmune diseases, inhibits arthritis, and aids brain recovery post-injury by blocking inflammation.Formule :C22H24ClN5ODegré de pureté :99.99%Couleur et forme :SolidMasse moléculaire :409.91TLR7 agonist 23
CAS :TLR7 agonist23 (compound 12b) is a potent agonist of Toll-like receptor-7 (TLR7), with an EC50 value of 0.15 uM. It is suitable for research in immune diseases.Formule :C21H22N4O2Couleur et forme :SolidMasse moléculaire :362.42TLR9-IN-1
CAS :TLR9-IN-1: selective, potent human TLR9 inhibitor (IC50: 7 nM), useful for researching immune-related diseases.Formule :C23H31N7OCouleur et forme :SolidMasse moléculaire :421.541Z105
CAS :1Z105, an orally active TLR4/MD2 ligand, facilitates dendritic cell maturation and antigen presentation, thereby preventing arthritis.Formule :C25H26N4O2SCouleur et forme :SolidMasse moléculaire :446.57CU-CPD107
CAS :CU-CPD107 selectively activates TLR8 and ssRNA, inhibits TLR8 with R848 (IC50=13.7 μM), and coactivates with ssRNA.Formule :C16H21IN2O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :400.25ABR-238901
CAS :ABR-238901 is an oral, active S100A8/A9 blocker that inhibits the interaction of S100A8/A9 with its receptors RAGE(receptor for advanced glycation end productsFormule :C11H9BrClN3O4SDegré de pureté :98.71% - 99.04%Couleur et forme :SolidMasse moléculaire :394.63Ref: TM-T39115
1mg116,00€5mg281,00€10mg447,00€25mg710,00€50mg973,00€100mg1.333,00€1mL*10mM (DMSO)310,00€Creatine ethyl ester
CAS :Creatine ethyl ester (CEE) is a readily available form of creatine commonly used in supplements. It can upregulate TLRs (TLR2, 3, 4, and TLR7) over a short period.Formule :C6H13N3O2Couleur et forme :SolidMasse moléculaire :159.186SARM1-IN-5
CAS :SARM1-IN-5 (compound 1-23-a) is an inhibitor of SARM1, useful for researching diseases related to axonal degeneration, including Alzheimer's disease, Parkinson's disease, amyotrophic lateral sclerosis (ALS), and multiple sclerosis (MS).Formule :C18H17FN6OCouleur et forme :SolidMasse moléculaire :352.37LHC-165
CAS :LHC-165 is an agonist of TLR7. It also has the potential to treat solid tumors.Formule :C29H32F2N3O7PDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :603.55SARM1-IN-4
CAS :SARM1-IN-4 (Compound 7) is an orally active SARM1 inhibitor that reduces plasma neurofilament light chain (NfL) levels in a mouse model following a 50 mg/kg oral dose. By inhibiting the NAD+ hydrolase activity of SARM1, it prevents programmed axon degeneration, making it useful for research in neurodegenerative and neurological diseases such as multiple sclerosis, amyotrophic lateral sclerosis, Parkinson's disease, and peripheral neuropathy.Formule :C13H17F2N3O2Couleur et forme :SolidMasse moléculaire :285.29TLR7 agonist 28
CAS :TLR7 agonist28 (compound 3) is a potent TLR7 agonist. This compound can be combined with anti-tumor monoclonal antibodies (mAb) for use in cancer immunotherapy.Formule :C26H25N9O7Couleur et forme :SolidMasse moléculaire :575.533TLR7/8/9 antagonist 2
CAS :TLR7/8/9 antagonist 2 is an orally active and highly bioavailable vTLR7/8/9 antagonist. It inhibits HEK/hTLR7, HEK/hTLR8, and HEK/hTLR9 with IC50s of 0.011 μM, 0.029 μM, and 0.052 μM, respectively. TLR7/8/9 antagonist 2 can be used to study auto-inflammatory diseases such as systemic lupus erythematosus or lupus nephritis.Formule :C23H31N7Degré de pureté :98%Couleur et forme :SoildMasse moléculaire :405.54
