TLR
Les récepteurs de type Toll (TLR) sont une classe de protéines qui jouent un rôle crucial dans le système immunitaire inné en reconnaissant les motifs moléculaires associés aux pathogènes (PAMP) et en initiant des réponses immunitaires. Les TLR sont impliqués dans la détection d'une large gamme de pathogènes, y compris les bactéries, les virus et les champignons, et sont essentiels pour l'activation des voies de signalisation inflammatoires. La dérégulation de la signalisation des TLR est associée à des maladies inflammatoires chroniques, des troubles auto-immuns et le cancer. Chez CymitQuimica, nous offrons une variété de modulateurs TLR de haute qualité pour soutenir vos recherches sur l'immunité innée, l'inflammation et les maladies infectieuses.
74 produits trouvés pour "TLR"
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PVP-037.2
CAS :PVP-037.2 is a TLR7/8 agonist that acts as an adjuvant to enhance vaccine-induced TH1 immune responses and boost the production of antigen-specific antibodies IgG1 and IgG2c.Formule :C23H20F3N5OCouleur et forme :SoildMasse moléculaire :439.43(R)-Thalidomide-pyrrolidine-C-piperidine-Ph-NH2
(R)-Thalidomide-pyrrolidine-C-piperidine-Ph-NH2 serves as the E3 ubiquitin ligase ligand and linker for PROTAC(R)-NX-2127, utilized in cancer research.Formule :C29H33N5O4Couleur et forme :SolidMasse moléculaire :515.6Ezeprogind
CAS :Ezeprogind, TLR9 inhibitor for Alzheimer's. Affordable Excellence: Reliable Quality You Can TrustFormule :C25H44N6Degré de pureté :99.28%Couleur et forme :SolidMasse moléculaire :428.66TLR8 agonist 8
CAS :TLR8 agonist8 (Compound II-72) is an agonist of Toll-like receptor 8 (TLR8) with an EC50 of 0.25-1 μM. It demonstrates stability in both human and mouse plasma and induces the secretion of the cytokine TNFα with an EC50 of less than 1 μM. In the MC38-HER2 xenograft mouse model, TLR8 agonist8 exhibits antitumor activity, achieving a tumor growth inhibition (TGI) rate of 89%.Formule :C53H63N11O10Couleur et forme :SolidMasse moléculaire :1014.14TLR8 agonist 7
CAS :TLR8 agonist7 is an agonist of Toll-like receptor 8 (TLR8) with an EC50 of less than 250 nM. It remains stable in human and mouse plasma and induces the secretion of the cytokine TNFα with an EC50 of less than 1 μM. In the MC38-HER2 xenograft mouse model, TLR8 agonist7 demonstrates antitumor activity, achieving a tumor growth inhibition (TGI) rate of 98%.Formule :C54H63N9O16Couleur et forme :SolidMasse moléculaire :1094.13TLR7 agonist 17
CAS :TLR7 agonist 17 (compound 20) functions as a highly effective TLR7 agonist, exhibiting EC 50 values of 12 nM for hTLR7 and 17 nM for mTLR7. Additionally, this compound has demonstrated anticancer activity [1].Formule :C25H37N7O3Couleur et forme :SolidMasse moléculaire :483.61TLR7 agonist 24
TLR7 agonist24 (Compound 21) is an agonist of TLR7 with an EC50 of 3.72 μM. When combined with Aluminum Hydroxide, it can be employed as a vaccine adjuvant to enhance the immune response to antigens from SARS-CoV-2 and hepatitis B.Couleur et forme :Odour SolidPam3CSK4
CAS :Pam3CSK4 is a synthetic triacylated lipopeptide (LP) that mimics the acylated amino terminus of bacterial LPs.Formule :C81H156N10O13SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :1510.23TLR7 agonist 3
CAS :TLR7 agonist 3 is a Toll-like receptor 7 (TLR7) agonist that has anticancer activity and is used in the study of diseases of the immune system.
Formule :C18H24N4ODegré de pureté :99.27%Couleur et forme :SolidMasse moléculaire :312.41Toll-like receptor modulator
CAS :Toll-like receptor modulator is a TLR7/8 modulator, which modulates immune function.Formule :C15H13F5N2O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :348.27Neoseptin-3
CAS :Neoseptin-3 is a novel small molecule agonist of mouse mTLR4/MD2 with EC50=18.5 μM that does not activate human TLR4/MD2.Formule :C29H34N2O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :474.59Motolimod
CAS :Motolimod (VTX-378) (VTX-2337) is an effective and specific Toll-like receptor (TLR) 8 agonist (EC50: 100 nM), > 50-fold selectivity over TLR7.Formule :C28H34N4O2Degré de pureté :97.43% - 99.66%Couleur et forme :SolidMasse moléculaire :458.6TLR7 agonist 2
CAS :TLR7 agonist 2 (TLR7-IN-1) is a specific and effective Toll-like Receptor 7 (TLR7) agonist (LEC=0.4 μM).
Formule :C17H16N6O2Degré de pureté :99.33%Couleur et forme :SolidMasse moléculaire :336.35TLR7/8 agonist 1
CAS :TLR7/8 agonist 1 is a toll-like receptor TLR7/TLR8 agonist with anticancer and antiviral activities and can be used to study immune-related diseases.Formule :C22H25N5Degré de pureté :99.4%Couleur et forme :SolidMasse moléculaire :359.47Telratolimod
CAS :Telratolimod (MEDI9197) is a toll-like receptors 7/8 agonist. It has an antitumor activity.Formule :C36H59N5O2Degré de pureté :98.61%Couleur et forme :SolidMasse moléculaire :593.89Enpatoran
CAS :Enpatoran is an inhibitor of TLR7(IC50 = 11.1 nM) and TLR8(IC50 = 24.1 nM).Formule :C16H15F3N4Degré de pureté :97.08% - 99.38%Couleur et forme :SolidMasse moléculaire :320.31Ref: TM-T9570
1mg113,00€5mg222,00€10mg334,00€25mg552,00€50mg782,00€100mg1.054,00€200mg1.414,00€1mL*10mM (DMSO)161,00€CU-CPT-8m
CAS :CU-CPT-8m (TLR8-specific antagonist) is an toll-like receptor 8 (TLR8) antagonist (IC50 : 67 nM)Formule :C14H12N4ODegré de pureté :99.00%Couleur et forme :SolidMasse moléculaire :252.27SM-324405
CAS :SM-324405 is an agonist of TLR7.Formule :C19H23N5O4Degré de pureté :97.83%Couleur et forme :SolidMasse moléculaire :385.42Ref: TM-T7860
2mg34,00€5mg52,00€10mg84,00€25mg138,00€50mg215,00€100mg306,00€200mg427,00€1mL*10mM (DMSO)57,00€CU-CPT9b
CAS :CU-CPT9b (TLR8-specific antagonist 1) is an antagonist of toll-like receptor 8 (TLR8; Kd = 21 nM).Formule :C16H13NO2Degré de pureté :98.1%Couleur et forme :SolidMasse moléculaire :251.28Ref: TM-T7302
1mg49,00€5mg92,00€10mg152,00€25mg245,00€50mg340,00€100mg504,00€200mg717,00€1mL*10mM (DMSO)105,00€MD2-IN-1
CAS :MD2-IN-1 is a Myeloid differentiation protein 2 (MD2) inhibitor with a KD of 189 μM for the recombinant human MD2 (rhMD2).Formule :C20H22O6Degré de pureté :99.87%Couleur et forme :SolidMasse moléculaire :358.39
