Récepteur IL
Les récepteurs de l'interleukine (récepteurs IL) sont un groupe de récepteurs qui se lient aux interleukines, une famille de cytokines jouant des rôles essentiels dans la régulation du système immunitaire, l'inflammation et l'hématopoïèse. La dérégulation de la signalisation des interleukines est associée à diverses maladies inflammatoires et auto-immunes, ce qui rend les récepteurs IL des cibles critiques pour les interventions thérapeutiques. Les antagonistes des récepteurs IL sont explorés pour le traitement de conditions telles que la polyarthrite rhumatoïde, le psoriasis et les maladies inflammatoires de l'intestin. Chez CymitQuimica, nous offrons une gamme de modulateurs de récepteurs IL de haute qualité pour soutenir vos recherches en signalisation des cytokines, immunologie et thérapie des maladies inflammatoires.
112 produits trouvés pour "Récepteur IL"
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Sarilumab
CAS :<p>Sarilumab: Potent IL-6 blocker, human antibody, reduces inflammation, treats rheumatoid arthritis.</p>Degré de pureté :97.4%Couleur et forme :LiquidMasse moléculaire :144.12 kDaIxekizumab
CAS :<p>Ixekizumab: IgG4 antibody, neutralizes IL-17A (<3 pM), treats severe plaque psoriasis & arthritis.</p>Degré de pureté :98.86% (SEC-HPLC) - > 99.3% (SDS-PAGE); 95.4% (SEC-HPLC)Couleur et forme :LiquidMasse moléculaire :146.2 kDaRisankizumab
CAS :<p>Risankizumab (BI 655066) is a monoclonal antibody for psoriasis, targeting IL-23, with high affinity (Kd <10 pM) and an IC50 of 2 pM.</p>Degré de pureté :SDS-PAGE:95.3%;SEC-HPLC:98.3%Couleur et forme :LiquidMasse moléculaire :145.85 kDaOlamkicept
CAS :<p>Olamkicept (FE-301) is a soluble gp130-Fc-fusion protein that inhibits interleukin 6 (IL-6) trans signaling.</p>Degré de pureté :98.2% (SDS-PAGE); 98.8% (SEC-HPLC) - 99.3% (SDS-PAGE); 97.6% (SEC-HPLC)Couleur et forme :LiquidBrodalumab
CAS :<p>Brodalumab (AMG 827), a human IgG2 monoclonal antibody, inhibits IL-17R, treating psoriasis.</p>Degré de pureté :98.3%Couleur et forme :LiquidMasse moléculaire :144.06 kDaBRD6989
CAS :<p>BRD6989, a cortistatin A analog, inhibits CDK8/19, enhances IL-10, and binds CDK8 with a 200 nM IC50.</p>Formule :C16H16N4Degré de pureté :99.43%Couleur et forme :SolidMasse moléculaire :264.33Enokizumab
CAS :<p>Enokizumab (MEDI-528) is a monoclonal antibody against interleukin IL-9. Enokizumab can be used to study asthma.</p>Degré de pureté :SDS-PAGE:95% SEC-HPLC:99.23%Couleur et forme :LiquidMasse moléculaire :145.98 kDa2-Benzothiazolamine
CAS :<p>2-ABT: nitrogen-rich heterocycle used in drug synthesis, inhibits P450, with anti-inflammatory, anticonvulsant, anticancer properties.</p>Formule :C7H6N2SDegré de pureté :99.09% - 99.3%Couleur et forme :Plates From Water Physical Description Odorless Gray To White Powder (Ntp 1992)Masse moléculaire :150.2PF-07038124 HCl
CAS :<p>PF-07038124 HCl is a selective and potent PDE4 inhibitor with an IC50 of 0.5 nM for PDE4B2.PF-07038124 HCl inhibits IL-13, IL-4, and IFNγ, and can be used in the study of skin disorders such as atopic dermatitis and plaque psoriasis.</p>Formule :C18H23BClNO4Degré de pureté :97.34% - 99.13%Couleur et forme :SoildMasse moléculaire :363.64Imsidolimab
CAS :<p>Imsidolimab (ANB 019) is a humanized anti-IL-36R monoclonal antibody that inhibits IL-36 signaling and can be used to study systemic pustular psoriasis.</p>Degré de pureté :99.1% (SDS-PAGE); 96.7% (SEC-HPLC) - 99.1% (SDS-PAGE); 96.7% (SEC-HPLC)Couleur et forme :LiquidOlokizumab
CAS :<p>Revdofilimab (ABBV-368) is a human IgG monoclonal antibody targeting OX 40 with potential anticancer activity.</p>Degré de pureté :99% (SDS-PAGE); 98.3% (SEC-HPLC) - 99% (SDS-PAGE); 98.3% (SEC-HPLC)Couleur et forme :LiquidDupilumab
CAS :<p>Dupilumab (REGN-668) is a systemic immunomodulator for AD.</p>Degré de pureté :95.00% - >99.2%Couleur et forme :LiquidVobarilizumab
CAS :<p>Vobarilizumab (ALX-0061) is a humanized specific antibody targeting IL-6R and ALB, used in research on autoimmune diseases like rheumatoid arthritis.</p>Degré de pureté :>95%Couleur et forme :LiquidMirikizumab
CAS :<p>Mirikizumab (LY3074828) is a humanized antibody targeting the p19 subunit of interleukin-23 (IL-23).</p>Degré de pureté :98.41% (SEC-HPLC) - 98.41% (SEC-HPLC)Couleur et forme :LiquidXeligekimab
CAS :<p>Xeligekimab (GR 1501) is a fully humanized monoclonal antibody that neutralizes IL-17A and has anti-inflammatory activity for the study of plaque psoriasis.</p>Degré de pureté :95%Couleur et forme :LiquidYQ128
CAS :<p>YQ128 is a potent and selective inhibitor of second-generation NLRP3 (NOD-like receptor P3) inflammasome(IC50 of 0.30 µM), with anti-inflammatory activity.</p>Formule :C27H29ClN2O4S2Degré de pureté :99.89%Couleur et forme :SolidMasse moléculaire :545.11Bermekimab
CAS :<p>Bermekimab (MABp1), an anti-interleukin-1α (IL-1α) monoclonal antibody.Bermekimab has potential anti-inflammatory activity to prevent skin inflammation.</p>Couleur et forme :LiquidMasse moléculaire :145.45 kDaAbrezekimab
CAS :<p>Abrezekimab (VR 942), a humanized antibody, blocks IL-13/IL-13Rα1, for asthma/lung disease study.</p>Degré de pureté :98.34% (SEC-HPLC) - 98.34% (SEC-HPLC)Couleur et forme :LiquidMasse moléculaire :48.1 kDaSiltuximab
CAS :<p>Siltuximab（CNTO-328） is a monoclonal antibody with anti-tumor activity targeting IL-6 for the study of giant lymph node hyperplasia (MCD) and COVID-19.</p>Degré de pureté :100% (SEC-HPLC) - > 95%Couleur et forme :LiquidMasse moléculaire :144.98 kDaElsilimomab
CAS :<p>Elsilimomab (B-E8) is a monoclonal antibody targeting IL-6, inhibiting the induction of bone marrow stromal cell senescence by dnmt3a mutation clones.</p>Degré de pureté :>95%Couleur et forme :LiquidBriakinumab
CAS :<p>Briakinumab (ABT-874) is a monoclonal antibody targeting IL-12, used in the research of psoriasis multiple sclerosis.</p>Degré de pureté :>95%Couleur et forme :LiquidPerakizumab
CAS :<p>Perakizumab (RG4934) is a humanized monoclonal antibody targeting IL-17A, used in the study of psoriatic arthritis and other autoimmune diseases.</p>Degré de pureté :95.28% (SEC-HPLC) - 99.66% (SEC-HPLC)Couleur et forme :LiquidMasse moléculaire :145.4 (kDa)Vunakizumab
CAS :<p>Vunakizumab is a humanized IgGκ monoclonal antibody targeting IL-17A, often linked to interleukin 22 to form Vunakizumab-IL22.</p>Degré de pureté :95%Couleur et forme :LiquidLevilimab
CAS :<p>Levilimab (BCD-089) is a fully humanized human monoclonal antibody targeting membrane-bound and soluble IL-6 R for the study of rheumatoid arthritis.</p>Degré de pureté :97.8% (SDS-PAGE); 97.3% (SEC-HPLC) - 97.8% (SDS-PAGE); 97.3% (SEC-HPLC)Couleur et forme :LiquidOrdesekimab
CAS :<p>Ordesekimab (AMG 714) is a human anti-IL-15 IgG1 κ monoclonal antibody for studying NRCD.</p>Degré de pureté :> 95%Couleur et forme :LiquidMasse moléculaire :145.12 kDaTildrakizumab
CAS :<p>Tildrakizumab (SCH 900222) is a humanized antibody against IL-23, with a 136 pM Kd, used for psoriasis research.</p>Degré de pureté :> 95%Couleur et forme :LiquidMasse moléculaire :144.44 kDaAmlexanox
CAS :<p>Amlexanox (AA673) treats ulcers by blocking leukotrienes, histamine, reducing inflammation, pain, and healing time.</p>Formule :C16H14N2O4Degré de pureté :99.67% - ≥95%Couleur et forme :White Crystalline SolidMasse moléculaire :298.29IL-15-IN-1
CAS :<p>IL-15-IN-1 is a selective and potent Interleukin 15 (IL-15) inhibitor, inhibiting the proliferation of IL-15-dependent cells (IC50: 0.8 μM).</p>Formule :C30H36N6O4SDegré de pureté :99.16%Couleur et forme :SolidMasse moléculaire :576.71Spesolimab
CAS :<p>Spesolimab (BI 655130) is an antibody targeting IL-36 receptor, key in immunity, for systemic pustular psoriasis and dermatitis studies.</p>Degré de pureté :> 95%Couleur et forme :LiquidMasse moléculaire :150 kDaNidanilimab
CAS :<p>Nidanilimab (CAN04) is an IL1RAP antibody with 1.10 pM affinity and antitumor effects on NSCLC and PDAC.</p>Degré de pureté :> 95%Couleur et forme :SoildMasse moléculaire :150 kDaTemtokibart
CAS :<p>Temtokibart is a humanized monoclonal antibody targeting IL22RA1, used in autoimmune and inflammatory disease research.</p>Couleur et forme :LiquidMasse moléculaire :145.5Pascolizumab
CAS :<p>Pascolizumab (SB-240683) is a humanized monoclonal antibody against IL-4. Pascolizumab has asthmatic effects and can be used to study allergic rhinitis.</p>Degré de pureté :> 95%Couleur et forme :LiquidMasse moléculaire :147.18 kDaPF-06342674
<p>PF-06342674 is a humanized monoclonal antibody targeting the IL-7 receptor-α, with immunoregulatory activity, used in Type 1 diabetes research.</p>Couleur et forme :LiquidMasse moléculaire :145.5kDaStapokibart
CAS :<p>Stapokibart (CM310) is a humanized monoclonal antibody targeting IL-4Rα, blocking IL-4Rα-mediated signaling. It is used in studies of atopic dermatitis.</p>Degré de pureté :96.09% (SEC-HPLC) - 96.09% (SEC-HPLC)Couleur et forme :LiquidDaclizumab
CAS :<p>Daclizumab (Zenapax), a humanized antibody, blocks IL-2 by targeting CD25, used in multiple sclerosis.</p>Degré de pureté :SDS-PAGE:95% SEC-HPLC:99.99%Couleur et forme :LiquidMasse moléculaire :144.12 kDaMacrophage-activating lipopeptide 2 TFA
<p>Macrophage-activating lipopeptide 2 TFA (MALP-2 TFA) is a diacylglycerol lipopeptide and TLR-2/TLR-6 agonist activates immune cell responses macrophages,</p>Formule :C99H167N19O30S·xC2HF3O2Degré de pureté :97.56%Couleur et forme :SolidMasse moléculaire :2135.56 (free base)CNTO 607
<p>CNTO 607 (Anti-IL-13 Antibody) is a humanized antibody targeting IL-13, useful for studying inflammation.</p>Degré de pureté :98% (SDS-PAGE); 98.3% (SEC-HPLC) - 98% (SDS-PAGE); 98.3% (SEC-HPLC)Couleur et forme :Odour LiquidAnti-inflammatory agent 42
CAS :<p>Anti-inflammatory agent 42 has anti-inflammatory activity and inhibits the expression of TNF-α and IL-6 in LPS-stimulated macrophages.</p>Formule :C20H12N2OSDegré de pureté :98.13%Couleur et forme :SolidMasse moléculaire :328.39Mepolizumab
CAS :<p>Mepolizumab (SB 240563) is a humanized monoclonal antibody neutralizing IL-5.</p>Degré de pureté :98% - 98%Couleur et forme :LiquidABX-IL8
<p>ABX-IL8 is a humanized antibody targeting IL-8, capable of interfering with tube formation in human umbilical vein endothelial cells.</p>Degré de pureté :>95%Couleur et forme :LiquidMasse moléculaire :145.5 kDaTorudokimab
<p>Torudokimab (ZB-880) is a monoclonal antibody that neutralizes interleukin 33 and can be used to study immune system diseases.</p>Degré de pureté :95.8% (SDS-PAGE); 96.2% (SEC-HPLC) - 95.8% (SDS-PAGE); 96.2% (SEC-HPLC)Couleur et forme :Odour LiquidDectrekumab
CAS :<p>Dectrekumab (QAX576) is a humanized monoclonal antibody targeting IL-13.</p>Degré de pureté :96.5% (SDS-PAGE); 97.1% (SEC-HPLC) - 96.5% (SDS-PAGE); 97.1% (SEC-HPLC)Couleur et forme :LiquidReslizumab
CAS :<p>Reslizumab (Sch 55700) is a humanized immunoglobulin G (IgG) 4 κ monoclonal antibody, thereby reducing eosinophil production and survival.</p>Degré de pureté :98.1% (SDS-PAGE); 98.6% (SEC-HPLC) - 98.1% (SDS-PAGE); 98.6% (SEC-HPLC)Couleur et forme :LiquidMasse moléculaire :N/AZiltivekimab
CAS :<p>Ziltivekimab (MEDI 5117) is a CHO-expressed humanized monoclonal antibody targeting IL-6/IFNb2 for use in immune system diseases.</p>Degré de pureté :95% - 97.9% (SDS-PAGE); 97.3% (SEC-HPLC)Couleur et forme :SoildGuselkumab
CAS :<p>Guselkumab (CNTO 1959) is a recombinant human IgG1 monoclonal antibody targeting the IL-23p19 subunit.</p>Degré de pureté :SDS-PAGE:95% SEC-HPLC:98.97%Couleur et forme :LiquidMasse moléculaire :144.8 kDaNosantine racemate
CAS :<p>Nosantine racemate is the racemate of Nosantine which is a IL-2 inducer or enhancer of IL-2 induction by phytohemagglutinin (PHA).</p>Formule :C14H22N4O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :278.35MyD88-IN-1
CAS :<p>MyD88-IN-1: Potent MyD88 inhibitor with anti-inflammatory effects, blocking NF-κB and TLR/IL-1 pathways; potential for cancer and inflammation treatment.</p>Formule :C23H24N6O7SDegré de pureté :>99.99%Couleur et forme :SoildMasse moléculaire :528.54Canakinumab
CAS :<p>Canakinumab: Human IL-1β antibody, anti-inflammatory, treats gout & coronary disease, IC50 of 43.6 pM (human), 40.8 pM (monkey).</p>Degré de pureté :98.8%Couleur et forme :LiquidMasse moléculaire :145.18 kDaY13g dihydrochloride
<p>Y13g dihydrochloride is a potent inhibitor of interleukin 6 (IL-6) and acetylcholinesterase (AChE) (both targets of Alzheimer's disease (AD) progression are</p>Formule :C16H25ClN2O4Degré de pureté :97.81%Couleur et forme :SoildMasse moléculaire :344.83ABzOH
CAS :<p>2-(Cyclopropylethynyl)benzoic acid: NSAID-like, anti-inflammatory, anti-tumor, hinders cytokines and various cancers.</p>Formule :C12H10O2Degré de pureté :99.43%Couleur et forme :SolidMasse moléculaire :186.21
