Récepteur IL
Les récepteurs de l'interleukine (récepteurs IL) sont un groupe de récepteurs qui se lient aux interleukines, une famille de cytokines jouant des rôles essentiels dans la régulation du système immunitaire, l'inflammation et l'hématopoïèse. La dérégulation de la signalisation des interleukines est associée à diverses maladies inflammatoires et auto-immunes, ce qui rend les récepteurs IL des cibles critiques pour les interventions thérapeutiques. Les antagonistes des récepteurs IL sont explorés pour le traitement de conditions telles que la polyarthrite rhumatoïde, le psoriasis et les maladies inflammatoires de l'intestin. Chez CymitQuimica, nous offrons une gamme de modulateurs de récepteurs IL de haute qualité pour soutenir vos recherches en signalisation des cytokines, immunologie et thérapie des maladies inflammatoires.
112 produits trouvés pour "Récepteur IL"
Trier par
Degré de pureté (%)
0
100
|
0
|
50
|
90
|
95
|
100
Anakinra
CAS :<p>Anakinra (Raleukin) is an antagonist of recombinant, nonglycosylated human IL-1R. It is the first biological agent to block the pro-inflammatory effects.</p>Formule :C759H1186N208O232S10Degré de pureté :95% - ≥95%Couleur et forme :SolidMasse moléculaire :17257.6IL-17A antagonist 1
CAS :<p>IL-17A antagonist 1 is an IL-17A antagonist for the study of interleukin-related inflammatory and immune diseases.</p>Formule :C33H41FN6O4Degré de pureté :99.46%Couleur et forme :SolidMasse moléculaire :604.71Anti-Human IL-17A
CAS :<p>Anti-Human IL-17A (Secukinumab H chain) is a human monoclonal antibody targeting IL-17A, offering high affinity and low immunogenicity for psoriasis.</p>Degré de pureté :98%Couleur et forme :LiquidMasse moléculaire :151 kDaAnti-Mouse IL-4 Antibody (11B11)
<p>Anti-Mouse IL-4 Antibody (11B11) is an inhibitory antibody targeting mouse IL-4, with the clone number 11B11.</p>Degré de pureté :99%Couleur et forme :Odour LiquidOssirene
CAS :<p>Ossirene (AS101), a potent in vitro and in vivo immunomodulator, is a novel inhibitor of IL-1beta converting enzyme.</p>Formule :C2H4Cl3O2Te·H4NDegré de pureté :≥98%Couleur et forme :SolidMasse moléculaire :312.05Apilimod mesylate
CAS :<p>Apilimod mesylate (STA 5326 mesylate) is a potent IL-12/IL-23 inhibitor.</p>Formule :C25H34N6O8S2Degré de pureté :99.51% - ≥95%Couleur et forme :SolidMasse moléculaire :610.7RO2959 Hydrochloride
CAS :<p>RO2959 Hydrochloride (RO2959 HCl) is a potent and selective inhibitor of CRAC channel(IC50: 402 nM). It is also a potent inhibitor of human IL-2.</p>Formule :C21H20ClF2N5OSDegré de pureté :99.24%Couleur et forme :SolidMasse moléculaire :463.93Dexamethasone Sodium Phosphate
CAS :<p>Dexamethasone Sodium Phosphate (Dexadreson) is a powerful anti-inflammatory and immunosuppressant synthetic glucocorticoid.</p>Formule :C22H30FO8P·2NaDegré de pureté :99.01% - 99.81%Couleur et forme :SolidMasse moléculaire :516.4IL-17A inhibitor 1
CAS :<p>IL-17A inhibitor 1 is a IL-17A inhibitor with IC50 of <9.45 nM in alphalisa assay. IL-17A inhibitor 1 inhibits HT-29 cells with IC50 of 9.3 nM.</p>Formule :C24H27F5N8O4Degré de pureté :99.37% - 99.37%Couleur et forme :SolidMasse moléculaire :586.51Apilimod
CAS :<p>Apilimod (STA 5326) inhibits the production of IL-12 and IL-23 and reduces dendritic cell infiltration in psoriasis.</p>Formule :C23H26N6O2Degré de pureté :99.38% - 99.89%Couleur et forme :SolidMasse moléculaire :418.49CP 424174
CAS :<p>CP 424174 blocks IL-1β processing (IC50: 210 nM), halts mature IL-1β formation, limits NLRP3, and is effective orally in vivo.</p>Formule :C22H29ClN2O4SDegré de pureté :>99.99%Couleur et forme :SolidMasse moléculaire :452.99Suplatast (Tosilate)
CAS :<p>Suplatast Tosilate (IPD 1151T) is a novel capsular anti-asthmatic drug. It ( IC50 above 100 μM) inhibits both IgE production, IL-4 and IL-5 synthesis.</p>Formule :C23H33NO7S2Degré de pureté :99.34% - 99.65%Couleur et forme :White Or Off-White CrystalsMasse moléculaire :499.64Esonarimod
CAS :<p>Esonarimod (KE-298) is an antirheumatic drug.</p>Formule :C14H16O4SDegré de pureté :97.44%Couleur et forme :SolidMasse moléculaire :280.34GIBH-130
CAS :<p>GIBH-130 markedly inhibits the IL-1β secretion by activated microglia (IC50: 3.4 nM). GIBH-130 is an effective inhibitor of neuroinflammation.</p>Formule :C20H20N6ODegré de pureté :99.52%Couleur et forme :SolidMasse moléculaire :360.41GSK717
CAS :<p>GSK717: potent, selective NOD2 inhibitor; disrupts NOD2/TLR2 synergy; no effect on NOD1, TNFR1, TLR2.</p>Formule :C28H28N4O2Degré de pureté :97.34% - 99.01%Couleur et forme :SolidMasse moléculaire :452.55VGX-1027
CAS :<p>VGX-1027 (GIT 27) is an isoxazole compound with various immunomodulatory properties.</p>Formule :C11H11NO3Degré de pureté :99.54% - 99.86%Couleur et forme :SolidMasse moléculaire :205.21Secukinumab
CAS :<p>Secukinumab is a fully humanized monoclonal anti-IL-17A antibody and the first in its class to be approved by the US Food and Drug Administration for the</p>Degré de pureté :97.4% (SDS-PAGE); 98.3% (SEC-HPLC) - 99.10%Couleur et forme :LiquidMasse moléculaire :147.93 kDaYM-90709
CAS :<p>YM-90709 is a new-type antagonist inhibiting the binding of interleukin-5 to the interleukin-5 receptor.</p>Formule :C22H21N3O2Degré de pureté :>99.99%Couleur et forme :SolidMasse moléculaire :359.42AX-024 hydrochloride
CAS :<p>AX-024 hydrochloride (AX-024 HCl) is an cytokine release inhibitor which can strongly inhibit the production of IL-6, TNFα, IFN-γ, IL-10 and IL-17A.</p>Formule :C21H23ClFNO2Degré de pureté :99.74%Couleur et forme :SolidMasse moléculaire :375.87Apilimod 2HCl
CAS :<p>Apilimod 2HCl (STA 5326 2HCl) is a PIKFYVE kinase inhibitor used in the study of amyotrophic lateral sclerosis.</p>Formule :C23H28Cl2N6O2Degré de pureté :98.41%Couleur et forme :SolidMasse moléculaire :491.41Clodronate disodium tetrahydrate
CAS :<p>Clodronate disodium tetrahydrate (Clastoban) inhibits bone resorption and soft tissue calcification.</p>Formule :CH10Cl2Na2O10P2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :360.92Satralizumab
CAS :<p>Satralizumab (SA-237) is a humanized antibody targeting interleukin-6 (IL-6), used in research on neuromyelitis optica spectrum disorder (NMOSD).</p>Degré de pureté :95%Couleur et forme :LiquidSirukumab
CAS :<p>Sirukumab (CNTO-136) is a humanized monoclonal antibody binding to IL-6, inhibiting IL-6-mediated signaling and transcription activator activation.</p>Degré de pureté :>95%Couleur et forme :LiquidMasse moléculaire :144.6 (kDa)Brazikumab
CAS :<p>Brazikumab (AMG 139) is a humanized antibody targeting IL-23 by binding to the P19 subunit, a selective IL-23p19 antagonist.</p>Degré de pureté :98% (SDS-PAGE); 97.7% (SEC-HPLC) - 98% (SDS-PAGE); 97.7% (SEC-HPLC)Couleur et forme :LiquidAfasevikumab
CAS :<p>Afasevikumab (RG 7624) is a fully humanised monoclonal antibody that targets and neutralises IL-17A and IL-17F,autoimmune diseases and inflammation.</p>Degré de pureté :95%Couleur et forme :LiquidGevokizumab
CAS :<p>Gevokizumab (S-78989) is a humanised monoclonal antibody targeting IL-1β, allosteric regulation, diabetes, cancer, inflammation, and cardiovascular diseases.</p>Degré de pureté :95%Couleur et forme :LiquidTirnovetmab
CAS :<p>Tirnovetmab (KIND-016) is a fully dog-derived monoclonal antibody targeting IL-31 with high affinity, suitable for investigating canine atopic dermatitis.</p>Degré de pureté :95% - 95%Couleur et forme :LiquidLebrikizumab
CAS :<p>Lebrikizumab is a humanised monoclonal antibody that targets and inhibits interleukin 13 (IL-13), suppressing Th2 inflammation.asthma and atopic dermatitis.</p>Degré de pureté :95%Couleur et forme :LiquidAnrukinzumab
CAS :<p>Anrukinzumab (IMA-638) is an anti-IL-13 mAb with anti-inflammatory effects, in development for ulcerative colitis and asthma.</p>Degré de pureté :95%Couleur et forme :LiquidPicankibart
CAS :<p>Picankibart (IBI112) is a human recombinant monoclonal antibody targeting IL-23p19, indicated for psoriasis treatment.</p>Degré de pureté :95% - 95%Couleur et forme :LiquidCasdozokitug
CAS :<p>Casdozokitug is a human IgG1κ anti-IL-27 antibody that blocks immunosuppressive activity, relevant in tumor immunology and immune checkpoint therapy research.</p>Degré de pureté :95% - 95%Couleur et forme :LiquidEbdarokimab
CAS :<p>Ebdarokimab (anti-IL-12/23 p40 mAb) inhibits the IL-12/IL-23 pathway and is under clinical investigation for SLE and plaque psoriasis.</p>Degré de pureté :95%Couleur et forme :LiquidInolimomab
CAS :<p>Inolimomab is a monoclonal antibody targeting CD25 (IL-2R α chain) for studying acute graft-versus-host disease (aGVHD).</p>Degré de pureté :95% - 95%Couleur et forme :LiquidBimekizumab
CAS :<p>Bimekizumab is a humanised monoclonal antibody targeting IL17A/IL17F, blocking inflammation-driven osteoblast differentiation.</p>Degré de pureté :>99.99%Couleur et forme :LiquidAnti-Mouse IL-6R Antibody (15A7)
<p>Anti-Mouse IL-6R Antibody (15A7) is an antibody inhibitor targeting mouse IL-6R, derived from rats, widely used in research and experiments</p>Degré de pureté :99% - 99%Couleur et forme :Odour LiquidZiralimumab
CAS :<p>Ziralimumab（ABX-RB2） is a monoclonal antibody that targets and inhibits IL-2 receptor, thereby modulating the immune response.</p>Degré de pureté :95%Couleur et forme :LiquidRademikibart
CAS :<p>Rademikibart (CBP-201) is a human monoclonal antibody selective for IL-4Rα, exhibiting strong affinity with a KD of 20.7 pM for human IL-4Rα epitopes, without</p>Degré de pureté :95%Couleur et forme :LiquidGumokimab
CAS :<p>Gumokimab (AK 111) is an anti-IL-17A mAb that blocks pro-inflammatory signaling, a candidate for psoriasis and ankylosing spondylitis.</p>Degré de pureté :95%Couleur et forme :LiquidManfidokimab
CAS :<p>Manfidokimab is an anti-IL-4Rα mAb that blocks IL-4/IL-13 signaling, in trials for atopic dermatitis.</p>Degré de pureté :95%Couleur et forme :LiquidBempikibart
CAS :<p>Bempikibart (ADX-914) is a fully humanised monoclonal antibody targeting IL-7Rα, inhibiting IL-17 and TSLP (Thymic stromal lymphopoietin), inflammation.</p>Degré de pureté :95% - 95%Couleur et forme :LiquidLusvertikimab
CAS :<p>Lusvertikimab (OSE-127) is a humanized anti-IL7R antibody with anti-leukemic efficacy and can be used to study leukemia.</p>Degré de pureté :95% - 98.4% (SDS-PAGE); 99% (SEC-HPLC)Couleur et forme :LiquidD228
CAS :<p>D228 is an oral anti-inflammatory,inhibi B and T lymphocytes, down-regulation of MyD88/TRAF6/p38 and up-regulation of IL-10,inflammatory bowel disease (IBD).</p>Formule :C22H28O12Degré de pureté :99.91%Couleur et forme :SolidMasse moléculaire :484.45Etokimab
CAS :<p>Etokimab (ANB-020) is a humanised monoclonal antibody targeting IL-33, neutrophil migration, atopic dermatitis, asthma, and sinusitis.</p>Degré de pureté :95%Couleur et forme :LiquidVopikitug
CAS :<p>Vopikitug is a humanized monoclonal antibody targeting IL-2RA with antitumor activity. It can be used to study cancer.</p>Degré de pureté :99.1% (SDS-PAGE); 96.5% (SEC-HPLC) - 99.1% (SDS-PAGE); 96.5% (SEC-HPLC)Couleur et forme :LiquidA-802715
CAS :<p>A-802715 is a novel methylxanthine derivative that decreases the endogenous formation and blood levels of pro-inflammatory substances and increases the</p>Formule :C16H26N4O3Degré de pureté :96.29%Couleur et forme :SolidMasse moléculaire :322.4BI605906
CAS :<p>BI605906 is an IKKβ inhibitor that can be used to study inflammatory skin diseases such as psoriasis.</p>Formule :C17H22F2N4O3S2Degré de pureté :97.14%Couleur et forme :SolidMasse moléculaire :432.51IL-4-inhibitor-1
CAS :<p>IL-4 inhibitor: Binds IL-4 (Kd=1.8 μM), blocks activity (EC50=1.81 μM), selective vs. IL-13, stops IL-4-JAK1-STAT6 in THP-1 monocytes (EC50=3.1 μM).</p>Formule :C18H12FN3O2Degré de pureté :98.78% - 99.53%Couleur et forme :SolidMasse moléculaire :321.31Resiniferatoxin
CAS :<p>Resiniferatoxin ((+)-Resiniferatoxin) is a highly potent synthetic TRPV1 agonist.Cost-effective and quality-assured.</p>Formule :C37H40O9Degré de pureté :93.08% - 99.34%Couleur et forme :SolidMasse moléculaire :628.71IL-2-IN-1
CAS :<p>IL-2-IN-1 is a potent inhibitor of IL-2 (IC50: 1978 nM) and exhibits anti-proliferative effects.</p>Formule :C17H12F6N4O2Degré de pureté :99.6%Couleur et forme :SolidMasse moléculaire :418.29Dersalazine
CAS :<p>Dersalazine, a PAF inhibitor, reduces IL-17 to treat colitis in rodents, potentially aiding ulcerative colitis patients.</p>Formule :C35H32N6O4Degré de pureté :99.62%Couleur et forme :SolidMasse moléculaire :600.67
