STAT
Les protéines STAT sont des composants critiques de la voie de signalisation JAK/STAT, qui transmet les signaux extracellulaires des cytokines et des facteurs de croissance au noyau cellulaire, influençant ainsi l'expression génique. Les protéines STAT sont impliquées dans la régulation des réponses immunitaires, de la croissance cellulaire, de la différenciation et de la survie. La dérégulation de la signalisation STAT est impliquée dans diverses maladies, y compris le cancer, les troubles auto-immuns et l'inflammation chronique. Chez CymitQuimica, nous proposons une gamme complète de modulateurs de la voie STAT pour soutenir vos recherches en transduction de signal, immunologie et développement thérapeutique.
110 produits trouvés pour "STAT".
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STAT6-IN-11
CAS :STAT6-IN-11 is a STAT6 inhibitor acting via the IL-13 pathway for related disease research.Formule :C27H29N7O3Degré de pureté :99.85%Masse moléculaire :499.56Eflepedocokin alfa
CAS :Eflepedocokin alfa is a recombinant IL-22/IgG2-Fc protein, potentially protecting cells and enhancing immune function and tissue repair.Couleur et forme :LiquidMNK8
CAS :MNK8 is a potent STAT3 inhibitor, impairs DNA binding, and inhibits liver cancer cell growth.Formule :C15H12N2O2Degré de pureté :99.93%Couleur et forme :SolidMasse moléculaire :252.268STAT3-IN-28
STAT3-IN-28 (compound 18) is an inhibitor of STAT3. It can suppress the activation of microglia and exhibits anti-neuroinflammatory effects. Additionally, STAT3-IN-28 is capable of crossing the blood-brain barrier.Formule :C20H23N3O2Couleur et forme :SolidMasse moléculaire :337.17903Anticancer agent 259
Anticanceragent 259 (Compound 3g) is a telmisartan-based cell death regulator that disrupts the STAT5 signaling pathway, thereby increasing the sensitivity of resistant cells to imatinib, with an SC50 of 1.5 μM.Formule :C30H26N2O2Couleur et forme :SolidMasse moléculaire :446.54STAT3-IN-31
STAT3-IN-31 (compound K2071), derived from STATtic, acts as an inhibitor of both STAT3 and mitotic processes. This compound interrupts mitotic progression and impacts the formation of the mitotic spindle. Additionally, STAT3-IN-31 hampers migration in glioblastoma cells, suppresses cellular proliferation within tumor spheroids, induces senescence in glioblastoma, and inhibits the growth of Temozolomide-resistant cells while reducing the secretion of the pro-inflammatory cytokine monocyte chemoattractant protein (MCP-1).Formule :C16H15NO3SCouleur et forme :SolidMasse moléculaire :301.36CMD178
CMD178 is an important polypeptide that consistently reduces the expression of Foxp3 and STAT5 by inhibiting the IL-2/s IL-2Rα signaling pathway.Formule :C46H59N9O7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :850.03Ac-GpYLPQTV-NH2 acetate
Ac-GpYLPQTV-NH2 acetate is a STAT3 inhibitor with an IC50 value of 0.33 μM. It also exhibits antitumor properties.Formule :C38H60N9O14P·xC2H4O2Couleur et forme :SolidMasse moléculaire :897.91 (free base)STAT3-IN-41
STAT3-IN-41 (Compound 16) is a prodrug of compound 1. It gradually releases compound 1, which inhibits the STAT3 signaling pathway. STAT3-IN-41 exhibits antitumor activity against lung cancer, hepatocellular carcinoma, and pancreatic cancer.Formule :C22H30F3NO7Couleur et forme :SolidMasse moléculaire :477.471JAK-STAT Compound Library
A unique collection of xnum JAK/STAT signaling targeted compounds for high throughput and high content screening;Couleur et forme :Odour Solid4-Chloroaniline-D4
CAS :4-Chloroaniline-D4 is the deuterium labeled 4-Chloroaniline. 4-Chloroaniline is a colourless to slightly amber-coloured crystalline solid with a mild aromatic odour.Formule :C6H6ClNMasse moléculaire :131.596STAT3-IN-23
CAS :STAT3-IN-23 (PY*LKTK) acts as a potent inhibitor of STAT3 [1].Formule :C36H61N8O12PCouleur et forme :SolidMasse moléculaire :828.89Stafib-1
CAS :Stafib-1 is a selective inhibitor of STAT5β targeting SH2 domain with an IC50 of 154 nM and a Ki of 44 nM.Formule :C26H24N2O11P2Degré de pureté :97.18%Couleur et forme :SolidMasse moléculaire :602.42Balsalazide
CAS :Balsalazide (Balsalazido) is an anti-inflammatory compound used in the treatment of Inflammatory Bowel Disease.Formule :C17H15N3O6Degré de pureté :99.31%Couleur et forme :Orange SolidMasse moléculaire :357.3175HJC0152 hydrochloride
CAS :HJC0152 hydrochloride (HJC0152) is a signal transducer and activator of transcription 3 (STAT3) inhibitor.Formule :C15H14Cl3N3O4Degré de pureté :99.01% - 99.06%Couleur et forme :SolidMasse moléculaire :406.648AS1810722
CAS :AS1810722, a fused bicyclic pyrimidine derivative, is an orally active and potent inhibitor of STAT6, demonstrating an IC50 of 1.9 nM.Formule :C25H25F2N7ODegré de pureté :99.13%Couleur et forme :SolidMasse moléculaire :477.5091TPCA-1
CAS :TPCA-1 (TPCA1) is an effective and specific IKK-2 inhibitor (IC50: 17.9 nM); shows >22-fold selectivity over IKK-1 and >550-fold selectivity over others kinasesFormule :C12H10FN3O2SDegré de pureté :95.03% - 99.90%Couleur et forme :SolidMasse moléculaire :279.29BP-1-102
CAS :BP-1-102 is an orally active, effective and specific STAT3 inhibitor.Formule :C29H27F5N2O6SDegré de pureté :99.25% - 99.44%Couleur et forme :White SolidMasse moléculaire :626.591Fraxinellone
CAS :1.Formule :C14H16O3Degré de pureté :99.35% - 99.88%Couleur et forme :Yellow SolidMasse moléculaire :232.275Astaxanthin
CAS :Astaxanthin, a keto-carotenoid and xanthophyll, offers antioxidant benefits, present in red aquatic species, and used as a colorant in animal feed.Formule :C40H52O4Degré de pureté :95.10% - 99.79%Couleur et forme :SolidMasse moléculaire :596.8385
