aMPc
L'AMPc est un second messager important dans de nombreux processus biologiques, y compris la régulation du métabolisme, l'expression des gènes et la croissance cellulaire. Dans la voie de signalisation MAPK, l'AMPc peut moduler l'activité de diverses kinases, y compris la PKA, qui influence à son tour la cascade MAPK. La dérégulation de la signalisation de l'AMPc est impliquée dans diverses maladies, notamment le cancer et les troubles cardiovasculaires. Chez CymitQuimica, nous offrons une variété de modulateurs de l'AMPc pour soutenir vos recherches en transduction de signaux, métabolisme et pathologie des maladies.
47 produits trouvés pour "aMPc"
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HJC0197
CAS :<p>HJC0197 is a selective Epac antagonist; blocks cAMP-induced activation with IC50=5.9 μM for Epac2.</p>Formule :C19H21N3OSDegré de pureté :98.05%Couleur et forme :SolidMasse moléculaire :339.45Bithionol
CAS :<p>Bithionol (Actamer), formerly marketed as an active ingredient in various topical drug products, was shown to be a potent photosensitizer with the potential to</p>Formule :C12H6Cl4O2SDegré de pureté :99.04%Couleur et forme :White Or Grayish-White Crystalline Powder Phenolic Odor (Ntp 1992)Masse moléculaire :356.05CE3F4
CAS :<p>CE3F4 is a selective antagonist of exchange protein directly activated by cAMP (Epac1; IC50s of 10.7 μM and 66 μM for Epac1 and Epac2(B), respectively).</p>Formule :C11H10Br2FNODegré de pureté :97.15% - 98.06%Couleur et forme :SolidMasse moléculaire :351.01Bucladesine sodium
CAS :<p>Bucladesine sodium (DC2797) is a cAMP analog with cell-permeable properties.</p>Formule :C18H23N5NaO8PDegré de pureté :96.56% - 99.76%Couleur et forme :White PowderMasse moléculaire :491.37A-3 hydrochloride
CAS :<p>A-3 hydrochloride: potent, reversible kinase antagonist; permeable; inhibits PKC, CKI, PKA, CKII, MLCK; Ki: 4.3-80 μM.</p>Formule :C12H14Cl2N2O2SDegré de pureté :99.32%Couleur et forme :SolidMasse moléculaire :321.22ESI-05
CAS :<p>ESI-05 (NSC-116966) is a specific 0.4 μM IC50 EPAC2 antagonist that blocks cAMP-induced EPAC2 and Rap1 activation.</p>Formule :C16H18O2SDegré de pureté :97.22%Couleur et forme :SolidMasse moléculaire :274.38JNJ-39758979
CAS :<p>JNJ-39758979: selective H4 receptor antagonist, Kis 12.5/5.3/25 nM (human/mouse/monkey), blocks histamine cAMP inhibition (pA2 7.9).</p>Formule :C11H19N5Degré de pureté :98.33% - 99.62%Couleur et forme :SolidMasse moléculaire :221.3MR-L2
CAS :<p>MR-L2 is a reversible and noncompetitive allosteric activator of long-isoform phosphodiesterase-4 (PDE4).</p>Formule :C19H16Cl3FN4ODegré de pureté :98.09% - 98.94%Couleur et forme :SolidMasse moléculaire :441.71Mirabegron
CAS :<p>Mirabegron (YM178) is a beta-3 adrenergic agonist that is used for treatment of overactive bladder syndrome.</p>Formule :C21H24N4O2SDegré de pureté :99.64%Couleur et forme :Light Yellow To Yellow SolidMasse moléculaire :396.51Adenosine 3'-monophosphate (sodium salt hydrate)
<p>Adenosine 3'-monophosphate (sodium salt hydrate) (3'-AMP) is a nucleotide and cAMP-generating agonist that elevates cAMP levels in NG108-15 cells.</p>Formule :C10H15N5NaO8PCouleur et forme :SolidMasse moléculaire :387.22MRS-1706
CAS :<p>MRS-1706: Ki of 1.39nM for A2B; selective inverse agonist; also affects A2A, A1, A3.</p>Formule :C27H29N5O5Degré de pureté :99.00%Couleur et forme :SolidMasse moléculaire :503.55BC 11-38
CAS :<p>BC 11-38 is a potent, selective PDE biodepressant which is mainly effective against PDE11 (IC50 : 0.28 μM).</p>Formule :C15H16N2OS2Degré de pureté :98.95% - 99.28%Couleur et forme :SolidMasse moléculaire :304.432-PCCA hydrochloride
CAS :<p>2-PCCA hydrochloride, a racemate, is a potent and selective GPR88 receptor agonist showing inhibition of GPR88-mediated cAMP production in HEK293 cells with an</p>Formule :C30H39Cl2N3ODegré de pureté :97.54% - 99.36%Couleur et forme :SoildMasse moléculaire :528.56OX04528
CAS :<p>OX04528 is an orally active and potent GPR84 biased agonist.OX04528 inhibits cAMP signaling and may be useful in cancer research.</p>Formule :C16H13F6NO2Degré de pureté :99.74%Couleur et forme :SoildMasse moléculaire :365.27GLP-1R modulator L7-028
CAS :<p>GLP-1R modulator L7-028 is a variant modulator that enhances affinity for GLP-1 and cAMP signaling.</p>Formule :C24H28N2O3Degré de pureté :98.76% - >99.99%Couleur et forme :SolidMasse moléculaire :392.49Anti-Cathelicidin/Camp Polyclonal Antibody
<p>Antibody Type: Rabbit Polyclonal<br><br>Application: IHC-P,IHC-Fr,ICC/IF,IF,ELISA<br><br>Reactivity: (predicted:Mouse,Rat)</p>Couleur et forme :LiquidMasse moléculaire :Theoretical: 19 kDa.Taprenepag
CAS :<p>Taprenepag (CP-544326) (CP-544326) is a potent and selective prostaglandin E2 receptor agonist (EC50 = 2.8 nM).</p>Formule :C24H22N4O5SDegré de pureté :98.89% - 99.15%Couleur et forme :SolidMasse moléculaire :478.52PSN 375963
CAS :<p>PSN 375963 (PSN 375963 hydrochloride) hydrochloride is a synthetic agonist of the endogenous ligand for GPR119.</p>Formule :C17H23N3ODegré de pureté :99.63%Couleur et forme :SolidMasse moléculaire :285.38Ro 20-1724
CAS :<p>Ro 20-1724 (4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone) is a widely used inhibitor of cyclic nucleotide phosphodiesterase with IC50 of 2.0 μM and Ki of 3.1</p>Formule :C15H22N2O3Degré de pureté :98.82% - 99.79%Couleur et forme :SolidMasse moléculaire :278.35(S)-(+)-Rolipram
CAS :<p>(S)-(+)-Rolipram ((+)-Rolipram) inhibits human monocyte cyclic AMP-specific PDE4 with IC50 of 0.75 μM, has anti-inflammatory and anti-depressant activity in the</p>Formule :C16H21NO3Degré de pureté :99.14%Couleur et forme :SolidMasse moléculaire :275.34Cyclic AMP
CAS :<p>cAMP and vitamin C treat viral myocarditis in children, enhancing cardiac and immune functions.</p>Formule :C10H12N5O6PDegré de pureté :98.01% - >99.99%Couleur et forme :SolidMasse moléculaire :329.21SAX-187
CAS :<p>SAX-187 (SAX-187) has high-affinity binding at the human 5-HT6 receptor.</p>Formule :C15H13ClN4O2S2Degré de pureté :97.82% - 98%Couleur et forme :SolidMasse moléculaire :380.87ESI-09
CAS :<p>ESI-09 is a new-typel noncyclic nucleotide EPAC antagonist.The IC50 values of ESI-09 for EPAC1 and EPAC2 is 3.2 and 1.4 μM, respectively.</p>Formule :C16H15ClN4O2Degré de pureté :97.24% - 99.57%Couleur et forme :SolidMasse moléculaire :330.77Glaucine
CAS :<p>Glaucine: antitussive, antioxidative, antiviral, may fight arthritis, boosts IL-10, hinders breast cancer cell spread by inhibiting MMP-9 and NF-κB.</p>Formule :C21H25NO4Degré de pureté :99.42% - 99.56%Couleur et forme :SolidMasse moléculaire :355.43RS-25344 hydrochloride
CAS :<p>RS 25344 hydrochloride is a phosphodiesterase (PDE) 4 inhibitor</p>Formule :C19H14ClN5O4Degré de pureté :99.25%Couleur et forme :SolidMasse moléculaire :411.8Setipiprant
CAS :<p>Setipiprant (ACT-129968) is an oral CRTH2 antagonist for asthma/allergy, targeting PGD2-induced inflammation (IC50: 6.0 nM).</p>Formule :C24H19FN2O3Degré de pureté :99.16%Couleur et forme :SolidMasse moléculaire :402.42Piclamilast
CAS :<p>Piclamilast (RP 73401) is a PDE4 inhibitor.</p>Formule :C18H18Cl2N2O3Degré de pureté :98.28% - 99.57%Couleur et forme :SolidMasse moléculaire :381.25Pinoresinol 4-O-β-D-glucopyranoside
CAS :<p>(+)-Pinoresinol-β-D-glucoside, also known as (+)-pinor, is a major active lignan furanoid found in Forsythia.</p>Formule :C26H32O11Degré de pureté :99.32% - >99.99%Couleur et forme :SolidMasse moléculaire :520.53Forskolin
CAS :<p>Forskolin (Coleonol) is a natural product, an adenylate cyclase activator (EC50=0.5 μM).</p>Formule :C22H34O7Degré de pureté :98.83% - 99.96%Couleur et forme :Less Crystalline Solid Colorless Crystalline SolidMasse moléculaire :410.5HJC0350
CAS :<p>HJC0350 is an effective and specific EPAC2 inhibitor (IC50: 0.3 μM), and no inhibition of Epac1.</p>Formule :C15H19NO2SDegré de pureté :99.27% - 99.65%Couleur et forme :SolidMasse moléculaire :277.38Enoximone
CAS :<p>Enoximone is a selective inhibitor of phosphodiesterase III (PDE3), with treatment of congestive heart failure.</p>Formule :C12H12N2O2SDegré de pureté :98.53%Couleur et forme :SolidMasse moléculaire :248.3LY404039
CAS :<p>LY404039 (pomaglumetad) is an effective agonist of recombinant human mGlu2(Ki =149 nM)/mGlu3(Ki =92 nM).</p>Formule :C7H9NO6SDegré de pureté :99% - 99.92%Couleur et forme :SolidMasse moléculaire :235.22Cathelicidin antimicrobial peptide Protein, Human, Recombinant (His & Myc & SUMO)
<p>Binds to bacterial lipopolysaccharides (LPS), has antibacterial activity.</p>Couleur et forme :Lyophilized PowderMasse moléculaire :24.7 kDa (predicted)Uliledlimab
CAS :<p>Uliledlimab, a humanized monoclonal antibody against CD73, reduces extracellular adenosine production and modulates immunosuppressive pathways.</p>Degré de pureté :95% - 95%Couleur et forme :LiquidI942
CAS :<p>I942 is a novel, selective ACyclic nucleotide (NCN) EPAC1 agonist that activates exchange proteins to regulate inflammatory gene expression in human umbilical</p>Formule :C20H19NO4SDegré de pureté :99.75%Couleur et forme :SolidMasse moléculaire :369.43ESI-08
CAS :<p>ESI-08 is an effective antagonist of EPAC2 with an IC50 of 8.4 μM. ESI-08 selectively blocks cAMP-induced EPAC activation but not cAMP-mediated PKA activation.</p>Formule :C20H23N3OSDegré de pureté :97.17%Couleur et forme :SolidMasse moléculaire :353.48EPAC 5376753
CAS :<p>EPAC 5376753 is an allosteric inhibitor of EPAC1 with an IC50 of 4 µM in Swiss 3T3 cells.</p>Formule :C15H8Cl2N2O3SDegré de pureté :97.48%Couleur et forme :SolidMasse moléculaire :367.21Rp-cAMPS sodium
CAS :<p>Rp-cAMPS sodium is a phosphorothioate analog of cAMP, a PKA inhibitor and cAMP antagonist that inhibits cAMP-dependent protein kinases.</p>Formule :C10H11N5NaO5PSDegré de pureté :99.71%Couleur et forme :SolidMasse moléculaire :367.25KI-7
CAS :<p>KI-7 is an adenosine A2B receptor positive allosteric modulator.</p>Formule :C23H18N2O2Degré de pureté :98.33%Couleur et forme :SolidMasse moléculaire :354.4UNC0006
CAS :<p>UNC0006 is a β-arrestin-biased dopamine D2 ligand.</p>Formule :C24H29Cl2N3O2Degré de pureté :99.35% - 99.97%Couleur et forme :SolidMasse moléculaire :462.41Torbafylline
CAS :<p>Torbafylline is a xanthine-based PDE inhibitor reducing protein breakdown via PDE4/cAMP/EPAC/PI3K/Akt in rats with burns, cancer, or sepsis.</p>Formule :C16H26N4O4Degré de pureté :98.66% - 99.13%Couleur et forme :SoildMasse moléculaire :338.4CJ-42794
CAS :<p>CJ-42794 (CJ-042794) is a selective antagonist of prostaglandin E receptor subtype 4 (EP4).</p>Formule :C22H17ClFNO4Degré de pureté :99.92%Couleur et forme :SolidMasse moléculaire :413.83NCGC00229600
CAS :<p>NCGC00229600: Allosteric inverse TSHR agonist; blocks TSH and antibody TSHR activation; for Graves' disease research.</p>Formule :C30H29N3O3Degré de pureté :99.31%Couleur et forme :SolidMasse moléculaire :479.57CW 008
CAS :<p>CW 008 is an agonist of the cAMP/PKA/CREB pathway, promoting osteogenic differentiation of bone marrow-derived mesenchymal stem cells (MSCs).a PKA activator.</p>Formule :C21H14F2N6O2Degré de pureté :97.39%Couleur et forme :SolidMasse moléculaire :420.37TP-10
CAS :<p>TP-10 is a selective inhibitor of PDE10A against other PDEs with IC50 of 0.8 nM.</p>Formule :C26H19F3N4ODegré de pureté :99.21%Couleur et forme :SolidMasse moléculaire :460.45LGD-6972
CAS :<p>LGD-6972 is an antagonist of glucagon receptor.</p>Formule :C43H46N2O5SDegré de pureté :98.8% - 99.62%Couleur et forme :SolidMasse moléculaire :702.9Vidupiprant
CAS :<p>Vidupiprant (AMG 853) is an effective dual antagonist of CRTH2 and prostanoid D receptor with IC50s of 8 nM and 35 nM in human plasma.</p>Formule :C28H27Cl2FN2O6SDegré de pureté :98.88%Couleur et forme :SolidMasse moléculaire :609.49
