MEK
La MEK est une kinase à double spécificité qui joue un rôle central dans la voie de signalisation MAPK/ERK en activant ERK par phosphorylation. La signalisation MEK est cruciale pour réguler la croissance, la survie et la différenciation cellulaires. Une activité anormale de la MEK a été impliquée dans divers cancers et troubles du développement, ce qui en fait une cible thérapeutique importante. Chez CymitQuimica, nous offrons une variété d'inhibiteurs et de modulateurs de la MEK pour soutenir vos recherches en oncologie, signalisation cellulaire et développement thérapeutique.
75 produits trouvés pour "MEK".
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Lidocaine Hydrochloride hydrate
CAS :Lidocaine Hydrochloride hydrate is an amide local anesthetic, has anti-inflammatory property.Formule :C14H22N2O·HCl·H2ODegré de pureté :99.95%Couleur et forme :SolidMasse moléculaire :288.82PD 198306
CAS :PD 198306: a MEK inhibitor with antihyperalgesic properties, reduces Streptozocin-boosted active ERK1.Formule :C18H16F3IN2O2Degré de pureté :99.66%Couleur et forme :SolidMasse moléculaire :476.23Lidocaine
CAS :Lidocaine, an amide local anesthetic, reduces pain and inflammation by dampening ICAM-1, cytokines, and neutrophil influx.Formule :C14H22N2ODegré de pureté :99.88% - >99.99%Couleur et forme :White SolidMasse moléculaire :234.3373MAPK Inhibitor Library
A unique collection of xnum cancer cell differentiation inducing compounds for high throughput and high content screening;Couleur et forme :Odour SolidFDA-Approved Kinase Inhibitor Library
A unique collection of xnum kinase inhibitors/regulators for specific targeting of kinases, ready for high-throughput screening and high-content screening.Couleur et forme :LiquidLuvometinib-d
Luvometinib-d is a deuterium-labeled version of Luvometinib, which is a mitogen-activated protein kinase (MEK) inhibitor with antitumor properties.MEK1/2-IN-3
MEK1/2-IN-3 (Compound M15) is an inhibitor of MEK1, with an IC50 value of 10.29 nM. It effectively suppresses tumor cell proliferation and migration, induces apoptosis, and exhibits good liver microsomal stability. MEK1/2-IN-3 is applicable in the study of solid tumors.Formule :C28H23F3IN3O4Couleur et forme :SolidMasse moléculaire :649.4Cobimetinib (R-enantiomer)
CAS :Cobimetinib R-enantiomer is the less active R-enantiomer of Cobimetinib which is a selective MEK inhibitor.Formule :C21H21F3IN3O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :531.318MS432
MS432 is a highly selective PD0325901-based VHL-recruiting PROTAC degrader for MEK1 and MEK2.Formule :C50H65F3IN7O6SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :1076.06MEK4 inhibitor-1
CAS :MEK4 inhibitor-1 targets MEK4 enzyme in pancreatic cancer, IC50=61 nM.Formule :C13H10FN3O2SCouleur et forme :SolidMasse moléculaire :291.3NST-628
CAS :NST-628 is a pan-RAF-MEK molecular glue that prevents RAF from phosphorylating and activating MEK. NST-628 inhibits the RAF-MEK signaling complex.Formule :C22H18F2N4O5SDegré de pureté :98.62% - 98.86%Couleur et forme :White SolidMasse moléculaire :488.46U0124
CAS :Inactive analog of U0126(MEK-1/2 inhibitor), used as a negative controlFormule :C8H10N4S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :226.32Midkine Protein, Human, Recombinant (His & Avi)
Midkine is a heparin-binding growth factor, originally reported as the product of a retinoic acid-responsive gene during embryogenesis, but currently viewed asDegré de pureté :> 95% as determined by Bis-Tris PAGE - > 95% as determined by Bis-Tris PAGECouleur et forme :White Lyophilized PowderMasse moléculaire :16.46 kDa (predicted) same as Tris-Bis PAGE result.Midkine Protein, Mouse, Recombinant (His)
Midkine is a heparin-binding growth factor, originally reported as the product of a retinoic acid-responsive gene during embryogenesis, but currently viewed asDegré de pureté :> 95% as determined by Bis-Tris PAGE - > 95% as determined by Bis-Tris PAGE > 95% as determined by HPLCCouleur et forme :Transparent SolutionMasse moléculaire :14.03 kDa (predicted). The protein migrates to 17-20 kDa based on Tris-Bis PAGE result.Midkine Protein, Human, Recombinant (His & Avi), Biotinylated
Midkine is a heparin-binding growth factor, originally reported as the product of a retinoic acid-responsive gene during embryogenesis, but currently viewed asCouleur et forme :Lyophilized PowderMasse moléculaire :16.46 kDa (predicted) same as Tris-Bis PAGE result.GSK1790627
CAS :GSK1790627, the N-deacetylated metabolite of Trametinib, represents an orally active MEK inhibitor that promotes autophagy and triggers apoptosis [1].Formule :C24H21FIN5O3Couleur et forme :SolidMasse moléculaire :573.36Anti-Midkine Antibody (5T766)
Anti-Midkine Antibody (5T766) is an antibody targeting Midkine. Anti-Midkine Antibody (5T766) can be used in ELISA, IHC.Couleur et forme :Odour LiquidTrametiglue
CAS :Trametiglue, a potent Trametinib derivative, selectively targets KSR-MEK and RAF-MEK through unique binding.Formule :C25H24FIN6O5SCouleur et forme :SolidMasse moléculaire :666.46Refametinib
CAS :Refametinib (RDEA119) (RDEA119, Bay 86-9766) is an effective, ATP non-competitive and specific inhibitor of MEK1/2 (IC50: 19/47 nM).Formule :C19H20F3IN2O5SDegré de pureté :99.85% - >99.99%Couleur et forme :SolidMasse moléculaire :572.34PD98059
CAS :PD98059 is an MEK inhibitor that inhibits MEK1 and MEK2 (IC50=2/50 μM) and is non-ATP-competitive.Formule :C16H13NO3Degré de pureté :98.63% - >99.99%Couleur et forme :Green SolidMasse moléculaire :267.28
