Ras
Les protéines Ras sont de petites GTPases qui agissent comme des commutateurs moléculaires dans la voie de signalisation MAPK, contrôlant la croissance, la différenciation et la survie cellulaires. Ras activé initie une cascade de signalisation qui inclut Raf, MEK et ERK, conduisant à diverses réponses cellulaires. Les mutations des gènes Ras sont courantes dans les cancers, faisant de Ras un point focal important de la recherche sur le cancer. Chez CymitQuimica, nous offrons une gamme de modulateurs de Ras pour soutenir vos recherches en biologie du cancer, transduction de signaux et développement thérapeutique.
154 produits trouvés pour "Ras"
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EHop-016
CAS :EHop-016 is a specific Rac GTPase inhibitor with IC50 of 1.1 μM for Rac1 in MDA-MB-231 and MDA-MB-435 cells, equally effective inhibition for Rac3.Formule :C25H30N6ODegré de pureté :98.99% - >99.99%Couleur et forme :SolidMasse moléculaire :430.55Ref: TM-T2427
5mg46,00€10mg70,00€25mg120,00€50mg202,00€100mg316,00€200mg467,00€500mg747,00€1mL*10mM (DMSO)49,00€1-(4-methansulfinylphenyl)ethanone
CAS :The compound inhibits Ras function and therefore inhibits the abnormal growth of cells.Formule :C9H10O2SDegré de pureté :99.48%Couleur et forme :SolidMasse moléculaire :182.24Ref: TM-T8870
1mg49,00€5mg144,00€10mg195,00€25mg273,00€50mg383,00€100mg532,00€200mg718,00€1mL*10mM (DMSO)96,00€Rhosin hydrochloride
CAS :Rhosin hydrochloride is a specific inhibitor of the RhoA subfamily Rho GTPases.Cost-effective and quality-assured.Formule :C20H20Cl2N6ODegré de pureté :97.33% - 98.92%Couleur et forme :SolidMasse moléculaire :431.318ARS-853
CAS :ARS-853 is an inhibitor of K-RASG12C(IC50 : 2.5 μM), a mutant form of K-RAS that accumulates in the active GTP-bound state in certain cancer cellsFormule :C22H29ClN4O3Degré de pureté :97.43% - 98.4%Couleur et forme :SolidMasse moléculaire :432.94Ref: TM-T7414
1mg142,00€5mg353,00€10mg525,00€25mg843,00€50mg1.144,00€100mg1.549,00€500mg3.087,00€1mL*10mM (DMSO)338,00€Antineoplaston A10
CAS :Antineoplaston A10 (NSC-648539) is a Ras inhibitor potentially for the treatment of glioma, lymphoma, astrocytoma and breast cancer.Formule :C13H14N2O3Degré de pureté :99.42%Couleur et forme :SolidMasse moléculaire :246.26Ref: TM-T7131
2mg44,00€5mg67,00€10mg103,00€25mg193,00€50mg295,00€100mg425,00€200mg595,00€1mL*10mM (DMSO)73,00€Phellodendrine chloride
CAS :Phellodendrine chloride combats kidney inflammation by blocking macrophage and T cell activity in glomeruli.Formule :C20H24ClNO4Degré de pureté :98.85% - 99.05%Couleur et forme :SolidMasse moléculaire :377.86Ref: TM-T5S0777
5mg50,00€10mg71,00€25mg101,00€50mg150,00€100mg215,00€200mg318,00€1mL*10mM (DMSO)58,00€Y16
CAS :Y16 is a G protein-coupled Rho GEFs inhibitor and also a specific inhibitor of LARG with a Kd of 76 nM.Cost-effective and quality-assured.Formule :C24H20N2O3Degré de pureté :98.26% - 99.85%Couleur et forme :SolidMasse moléculaire :384.43Ref: TM-T3553
1mg34,00€2mg48,00€5mg70,00€10mg109,00€25mg177,00€50mg263,00€100mg389,00€1mL*10mM (DMSO)77,00€NSC 23766 trihydrochloride
CAS :NSC 23766 trihydrochloride (Rac1 Inhibitor) is an inhibitor of Rac GTPase targeting Rac activation by GEFs; no inhibitory for RhoA or Cdc42.Formule :C24H35N7·3HClDegré de pureté :96.48% - 99.54%Couleur et forme :SolidMasse moléculaire :530.96Ref: TM-T6342
2mgÀ demander5mg55,00€10mg88,00€25mg145,00€50mg260,00€100mg380,00€1mL*10mM (DMSO)64,00€CID-1067700
CAS :CID-1067700 is one of the first identified competitive inhibitors of nucleotide binding by Ras-related GTPases（Rab7 with a Ki of 13 nM).Formule :C18H18N2O4S2Degré de pureté :99.46%Couleur et forme :SolidMasse moléculaire :390.48Ref: TM-T7558
1mg34,00€2mg49,00€5mg71,00€10mg105,00€25mg178,00€50mg234,00€100mg303,00€1mL*10mM (DMSO)78,00€Z62954982
CAS :Z62954982 (ZINC08010136) is a Rac1 inhibitor that inhibits Rac1 activation and reduces proliferation, p38 phosphorylation, and IL-6 levels in pulmonary arteriesFormule :C20H21N3O5SDegré de pureté :98.28%Couleur et forme :SolidMasse moléculaire :415.46Ref: TM-T37113
1mg35,00€5mg75,00€10mg105,00€25mg173,00€50mg255,00€100mg371,00€200mg530,00€1mL*10mM (DMSO)87,00€AZD0022
CAS :AZD0022 is a selective, reversible, and orally active KRAS G12D inhibitor, exhibits tumour marker inhibition in PDAC and NSCLC models.Formule :C34H30F4N6ODegré de pureté :98.73%Couleur et forme :SoildMasse moléculaire :614.64Deltarasin
CAS :Deltarasin is a small molecular inhibitor of KRAS-PDEδ interaction with Kd of 38 nM for binding to purified PDEδ.Formule :C40H37N5ODegré de pureté :99.4%Couleur et forme :SolidMasse moléculaire :603.756H05
CAS :6H05 (K-Ras inhibitor) is a selective, allosteric inhibitor of oncogenic mutant K-Ras(G12C).Formule :C20H30ClN3O2S3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :476.12MCP110
CAS :MCP110 is an inhibitor of the interaction of Ras with Raf-1 and can be used in studies about the treatment of human tumors.Formule :C33H36N2O3Degré de pureté :97.23%Couleur et forme :OilMasse moléculaire :508.65Ref: TM-T24437
1mg34,00€5mg92,00€10mg160,00€25mg276,00€50mg400,00€100mg532,00€500mg1.063,00€1mL*10mM (DMSO)103,00€Digeranyl bisphosphonate
CAS :Digeranyl bisphosphonate (DGBP) is a potent geranylgeranyl pyrophosphate (GGPP) synthase inhibitor that inhibits geranyl pyrophosphorylation of Rac1.DigeranylFormule :C21H34Na4O6P2Degré de pureté :98.5%Couleur et forme :SolidMasse moléculaire :536.4Methylophiopogonanone B
CAS :1. Methylophiopogonanone B (MOPB) induces cell morphological change and Rho activation via melanocyte dendrite retraction and stress fiber formation.Formule :C19H20O5Degré de pureté :99.24% - 99.83%Couleur et forme :SolidMasse moléculaire :328.36Ref: TM-T5S1261
1mg84,00€5mg178,00€10mg295,00€25mg497,00€50mg708,00€100mg964,00€200mg1.288,00€1mL*10mM (DMSO)192,00€KRAS inhibitor-7
CAS :KRAS inhibitor-7 is a potent KRAS G12C inhibitor.Formule :C26H27ClF2N6O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :528.98KRas G12C inhibitor 3
CAS :KRas G12C inhibitor 3 is a compound that inhibits KRas G12C.Formule :C32H36ClN7O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :586.13ESI-08
CAS :ESI-08 is an effective antagonist of EPAC2 with an IC50 of 8.4 μM. ESI-08 selectively blocks cAMP-induced EPAC activation but not cAMP-mediated PKA activation.Formule :C20H23N3OSDegré de pureté :97.17%Couleur et forme :SolidMasse moléculaire :353.48KRAS inhibitor-6
CAS :KRAS inhibitor-6 is a potent KRAS G12C inhibitor.Formule :C27H30ClF2N5O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :546.01
