mAPK p38
Les p38 MAPK sont un sous-groupe de MAPK qui répondent aux signaux de stress et sont impliqués dans la régulation de l'inflammation, de la différenciation cellulaire, de l'apoptose et de l'autophagie. La signalisation p38 MAPK est cruciale dans les réponses immunitaires et est impliquée dans diverses maladies, y compris les affections inflammatoires chroniques, le cancer et les troubles neurodégénératifs. Chez CymitQuimica, nous proposons une gamme complète d'inhibiteurs et de modulateurs de p38 MAPK pour soutenir vos recherches sur l'inflammation, la réponse au stress et le développement thérapeutique.
112 produits trouvés pour "mAPK p38"
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AZD7624
CAS :AZD7624 is an p38 inhibitor. It has potent anti-inflammatory activity.Formule :C27H30FN5O3Degré de pureté :98.82%Couleur et forme :SolidMasse moléculaire :491.56Ref: TM-T14381
1mg73,00€5mg160,00€10mg250,00€25mg455,00€50mg682,00€100mg1.017,00€1mL*10mM (DMSO)170,00€Aspirin
CAS :Aspirin (Acetylsalicylic Acid) is a COX inhibitor. Aspirin has anti-inflammatory, antipyretic and analgesic activities. Cost-effective and quality-assured.Formule :C9H8O4Degré de pureté :99.78% - 99.91%Couleur et forme :White Solid CrystallineMasse moléculaire :180.16SB220025
CAS :SB220025 is a P38 mitogen-activated protein kinase inhibitor that inhibits p56Lck and PKC, and inhibits angiogenesis.Formule :C18H19FN6Degré de pureté :99.44%Couleur et forme :SolidMasse moléculaire :338.38Carbimazole
CAS :Carbimazole, an imidazolium-based thyroid blocker, turns to MMI in the body. Used in Graves' disease research.Formule :C7H10N2O2SDegré de pureté :99.98%Couleur et forme :SolidMasse moléculaire :186.23Dihydrocaffeic acid
CAS :Dihydrocaffeic acid, a chlorogenic acid metabolite, has antioxidant, anti-Alzheimer's, neuroprotective, and lipid-lowering properties.Formule :C9H10O4Degré de pureté :98.63%Couleur et forme :SolidMasse moléculaire :182.17BI-3406
CAS :BI-3406 is an orally active, highly potent and selective between KRAS and Son of Sevenless 1 (SOS1) interaction inhibitor(IC50 : 6 nM),with anticancer activity.Formule :C23H25F3N4O3Degré de pureté :99.2% - 99.66%Couleur et forme :SolidMasse moléculaire :462.46Ref: TM-T12979
1mg73,00€5mg160,00€10mg250,00€25mg464,00€50mg663,00€100mg919,00€500mg1.833,00€1mL*10mM (DMSO)170,00€Oxidopamine hydrochloride
CAS :Oxidopamine hydrochloride (6-Hydroxydopamine hydrochloride) is an neurotransmitter dopamine antagonist.Formule :C8H12ClNO3Degré de pureté :98.34% - 99.85%Couleur et forme :Physical Description Beige Solid (Ntp 1992)Masse moléculaire :205.64Dehydrocorydaline chloride
CAS :Dehydrocorydaline chloride (13-Methylpalmatine chloride) is an alkaloid with anti-inflammatory and anti-cancer activity. Can improve the activation of p38 MAPK.Formule :C22H24ClNO4Degré de pureté :99.53%Couleur et forme :SolidMasse moléculaire :401.88Ref: TM-T10990
1mg55,00€5mg105,00€10mg152,00€25mg250,00€50mg375,00€100mg533,00€1mL*10mM (DMSO)117,00€Oxidopamine hydrobromide
CAS :Oxidopamine hydrobromide (6-OHDA hydrobromide) is a neurotransmitter dopamine antagonist.Formule :C8H12BrNO3Degré de pureté :98.22% - 99.88%Couleur et forme :Beige To Brown Fine Crystalline PowderMasse moléculaire :250.09LXH254
CAS :LXH254 is a B/C RAF inhibitor with IC50 values of 0.2 nM and 0.07 nM for inhibiting BRAF and CRAF.Cost-effective and quality-assured.Formule :C25H25F3N4O4Degré de pureté :98.3% - 99.92%Couleur et forme :SolidMasse moléculaire :502.49Ref: TM-T11898
1mg52,00€5mg122,00€10mg185,00€25mg363,00€50mg567,00€100mg690,00€200mg948,00€500mg1.444,00€1mL*10mM (DMSO)135,00€Dilmapimod
CAS :Dilmapimod (SB-681323) is a potent inhibitor of p38 MAPK ,it potentially suppresses inflammation in chronic obstructive pulmonary disease.Formule :C23H19F3N4O3Degré de pureté :97.53%Couleur et forme :SolidMasse moléculaire :456.42PF-3644022
CAS :PF-3644022 is a selective MK2 inhibitor, effective against TNFα (IC50: 5.2 nM, Ki: 3 nM), with anti-inflammatory properties. Also blocks MK3 and PRAK.Formule :C21H18N4OSDegré de pureté :98.13%Couleur et forme :SolidMasse moléculaire :374.46Ref: TM-T16501
1mg37,00€5mg111,00€10mg202,00€25mg416,00€50mg620,00€100mg832,00€500mg1.663,00€1mL*10mM (DMSO)187,00€Hesperetin
CAS :Hesperetin belongs to the flavanone class of flavonoids.Formule :C16H14O6Degré de pureté :98.45% - 99.27%Couleur et forme :SolidMasse moléculaire :302.28Klotho-derived peptide 1 hydrochloride
Klotho-derived peptide 1 (KP1 human) hydrochloride inhibits the interaction between TGF-β and TGF-β receptor 2, suppressing the activation of TGF-β-induced Smad2/3 and mitogen-activated protein kinase (MAPK). Additionally, it exhibits antifibrotic and renal protective effects in mouse models.Couleur et forme :Odour SolidNR-11c
NR-11c is a selective and potent p38α PROTAC degrader. It effectively degrades p38α in various tumor cells. When administered to mice via intraperitoneal or tail vein injection, NR-11c primarily acts in the liver. It is used for cancer research.Formule :C59H71BrF2N10O8SMasse moléculaire :1198.22MAP3K5-IN-1
CAS :Compound 7, also known as 3′-O-Demethyl-4′-N-demethyl-4′-N-acetyl-4′-epi-staurosporine, serves as an inhibitor of protein kinases, displaying IC50 values of 0.092 μM for PKC-α, 0.26 μM for ROCK, and 0.77 μM for ASK1. Additionally, this compound exhibits significant cytotoxicity towards PC-3 cancer cells, with an IC50 of 0.16 μM [1].Formule :C28H24N4O4Couleur et forme :SolidMasse moléculaire :480.51Cyclotraxin B
CAS :TrkB receptor antagonist; inhibits BDNF-TrkB signaling (IC50 = 0.30 nM); alters receptor shape; may reduce anxiety in mice.
Formule :C48H73N13O17S3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1200.36p38 MAP Kinase Inhibitor Ⅵ
CAS :p38 MAP Kinase Inhibitor Ⅵ is a potent p38 MAP Kinase inhibitor with anti-inflammatory activity.Formule :C16H13FN2OS2Degré de pureté :98.53%Couleur et forme :SolidMasse moléculaire :332.42PDE4-IN-26
PDE4-IN-26 (Compound A5) is an orally active, highly selective inhibitor of PDE4. It exhibits anti-inflammatory properties by inhibiting p38 MAPK phosphorylation. In mouse models of acute lung injury and chronic obstructive pulmonary disease, PDE4-IN-26 reduces lung inflammation, damage, and fibrosis, while promoting sputum secretion and alleviating cough. It is useful for researching lung injury-related diseases.Formule :C22H18F2N4O3SCouleur et forme :SolidMasse moléculaire :456.47DB-10
DB-10 serves as a precursor to 3-nbutylphthalide (NBP). It is absorbed by cells in a temperature and energy-dependent manner through the pyrilamine cation transporter. DB-10 enhances cell survival and rapidly converts into an active form in vivo, increasing accumulation within the brain. This compound is applicable in ischemic stroke research.Couleur et forme :Odour Solid
