Transporteur membranaire/Canal ionique
Les inhibiteurs des transporteurs membranaires et des canaux ioniques sont des composés qui bloquent la fonction des protéines responsables du transport des ions, des nutriments et d'autres molécules à travers les membranes cellulaires. Ces inhibiteurs sont essentiels pour étudier la régulation de l'homéostasie cellulaire, la transduction des signaux et la neurotransmission. Les inhibiteurs des transporteurs membranaires et des canaux ioniques sont également importants pour développer des traitements contre des troubles tels que l'épilepsie, les maladies cardiovasculaires et les syndromes métaboliques. Chez CymitQuimica, nous offrons une sélection diversifiée d'inhibiteurs de haute qualité des transporteurs membranaires et des canaux ioniques pour soutenir vos recherches en physiologie, neurosciences et pharmacologie.
Sous-catégories appartenant à la catégorie "Transporteur membranaire/Canal ionique"
- ABC(3 produits)
- ATPase(93 produits)
- Récepteur de l'adiponectine(5 produits)
- CFTR(64 produits)
- Récepteur CGRP(51 produits)
- Canal calcique(493 produits)
- Canal chlorure(49 produits)
- Récepteur GABA(336 produits)
- Transporteur de monoamine(23 produits)
- Transporteur de monocarboxylate(17 produits)
- NKCC(2 produits)
- NPC1L1(3 produits)
- Cotransporteur Na-K-Cl(8 produits)
- OAT(27 produits)
- OCT(7 produits)
- P-gp(53 produits)
- Canal potassique(276 produits)
- Pompe à protons(39 produits)
- SGLT(30 produits)
- Canal sodique(202 produits)
- Canal TRP/TRPV(92 produits)
Affichez 13 plus de sous-catégories
2270 produits trouvés pour "Transporteur membranaire/Canal ionique"
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GDC-6599
CAS :<p>GDC-6599 (Example 8) is an orally active inhibitor of the TRPA1 channel, potentially useful for researching TRPA1-mediated conditions, including pain [1].</p>Formule :C20H19ClN6O3Couleur et forme :SolidMasse moléculaire :426.86MONIRO-1
CAS :<p>MONIRO-1 blocks T/N-type Ca²⁺ channels: hCav2.2 (IC50: 34μM), hCav3.1 (3.3μM), hCav3.2 (1.7μM), hCav3.3 (7.2μM).</p>Formule :C23H24ClFN4O3Couleur et forme :SolidMasse moléculaire :458.92γ-Kainylglutamic acid
CAS :<p>gamma-Kainylglutamic acid is a selective amino acid-induced neuroexcitation antagonist.</p>Formule :C15H22N2O7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :342.34(-)-Bicuculline methochloride
CAS :<p>(-)-Bicuculline methochloride is a potent antagonist of GABAA receptor.</p>Formule :C21H20ClNO6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :417.84Y-27152
CAS :<p>Y-27152 is a prodrug of the KATP (Kir6) channel opener Y-26763 and is a long-acting K+ channel opener.</p>Formule :C21H22N2O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :366.41P-1075
CAS :<p>P-1075 activates SUR2-KIR6 channels at 45 nM; may open mitoKATP channels and protect the heart.</p>Formule :C12H17N5Degré de pureté :99.85%Couleur et forme :SolidMasse moléculaire :231.3FGIN-1-27
CAS :<p>FGIN-1-27 is a high-affinity agonist of the translocator protein and a specific peripheral benzodiazepine receptor (PBR) ligand(Ki = 5.0 nM).</p>Formule :C28H37FN2ODegré de pureté :99.86%Couleur et forme :SolidMasse moléculaire :436.6CS-526
CAS :<p>CS-526 is a reversible proton pump inhibitor targeting the K+ site on H+,K+-ATPase, reducing gastric acid secretion and preventing mucosal lesions.</p>Formule :C20H22FN3OCouleur et forme :SolidMasse moléculaire :339.41NMDA receptor modulator 6
CAS :<p>NMDA receptor regulator 6 (Compound 183) is an effective NMDA receptor regulator and has research value in neurological disorders.</p>Formule :C20H17FN2O4SCouleur et forme :SolidMasse moléculaire :400.42Pumaprazole
CAS :<p>Pumaprazole (BY-841) is an antagonist of a reversible proton pump.</p>Formule :C19H22N4O2Degré de pureté :99.91%Couleur et forme :SolidMasse moléculaire :338.4ROMK-IN-32
CAS :<p>ROMK-IN-32 is an inhibitor of the extra-renal medullary potassium channel (ROMK) (IC50: 35 nM) and also inhibits hERG (IC50: 22 μM).</p>Formule :C24H28N4O5Couleur et forme :SolidMasse moléculaire :452.5N-Linolenoylethanolamine
CAS :<p>N-Linolenoylethanolamine (18:3 NAE), an endocannabinoid, functions as a vanillin receptor (TRPV1) agonist [1].</p>Formule :C20H35NO2Couleur et forme :SolidMasse moléculaire :321.505BMS-986169
CAS :<p>BMS-986169 is a high-affinity and selective negative allosteric modulator of the NMDA receptor GluN2B subunit, depression.</p>Formule :C23H27FN2O2Degré de pureté :97.61%Couleur et forme :SolidMasse moléculaire :382.47DNDS
CAS :<p>DNDS is a channel blocker of voltage-dependent cystic fibrosis transmembrane conductance regulator (CFTR).</p>Formule :C14H8N2Na2O10S2Degré de pureté :99.92%Couleur et forme :Physical Description White Powder (Ntp 1992)Masse moléculaire :474.33Pristinamycin IA
CAS :<p>Pristinamycin IA (Mikamycin B) is a substrate for the P-glycoprotein and a cyclo-peptidic macrolactone antibiotic.</p>Formule :C45H54N8O10Degré de pureté :97.44%Couleur et forme :SolidMasse moléculaire :866.96CFTR corrector 6
CAS :<p>CFTR corrector 6, a potent CFTR potentiator, aids cystic fibrosis research and related disorders.</p>Formule :C22H13F4N9Couleur et forme :SolidMasse moléculaire :479.39SLC13A5-IN-1
CAS :<p>SLC13A5-IN-1 is a selective inhibitor of sodium-citrate co-transporter (SLC13A5),completely blocks the uptake of 14C-citrate(IC50 : 0.022 μM in HepG2 cells).</p>Formule :C19H19Cl3N2O3SDegré de pureté :99.67%Couleur et forme :SolidMasse moléculaire :461.79TRPC5 modulator-1
CAS :<p>TRPC5 modulator-1 (Compound 9) is a TRPC5 modulator (IC50<1 nM) that can be used to study neuropsychiatric disorders.</p>Formule :C23H27FN2O4Couleur et forme :SolidMasse moléculaire :414.47AC-4
CAS :<p>AC-4 is a blocker of photoswitchable TRPV1 channel.</p>Formule :C26H25F3N4O2SCouleur et forme :SolidMasse moléculaire :514.56PF 04531083
CAS :<p>PF 04531083 is a selective blocker of the NaV1.8 channel. PF 04531083 can be used for neuropathic and inflammatory pain studies.</p>Formule :C17H16ClN5O2Degré de pureté :99.85%Couleur et forme :SolidMasse moléculaire :357.79CP 154526
CAS :<p>CRF1 receptor antagonist</p>Formule :C23H33ClN4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :400.99AMPA receptor modulator-2
CAS :<p>AMPA receptor modulator-2 is a modulator of AMPA receptor. The pIC50 value for TARPγ2 dependent AMPA receptor is 10.1.</p>Formule :C15H6F6N4OSDegré de pureté :99.8%Couleur et forme :SolidMasse moléculaire :404.29TRPC3/6-IN-2
CAS :<p>TRPC3/6-IN-2 is a potent inhibitor of TRPC3 and TRPC6, exhibiting IC50 values of 16 nM for TRPC3 and 29.8 nM for TRPC6, respectively [1].</p>Formule :C18H23F2N5Couleur et forme :SolidMasse moléculaire :347.41Antiarrhythmic agent-1
CAS :<p>Antiarrhythmic agent-1 (example I), functioning as an antiarrhythmic agent and an IKr potassium channel blocker (IC 50 <1 μM), effectively inhibits cardiac</p>Formule :C25H27N3O4SCouleur et forme :SolidMasse moléculaire :465.56A-1165442
CAS :<p>A-1165442 is a competitive TRPV1 antagonist. For human TRPV, the IC50 values is 9 nM.</p>Formule :C22H20ClF2N3O2Couleur et forme :SolidMasse moléculaire :431.86Dibutyryl-cGMP sodium
CAS :<p>Bt2cGMP sodium is a cGMP analog, activates PKG, inhibits platelet [3H]-arachidonate, and induces analgesia via K+ channels.</p>Formule :C18H24N5NaO9PDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :508.38NMDA receptor modulator 4
CAS :<p>NMDA receptor modulator 4 (Compound 169) can be used for the research of neurological disorder that is a potent modulator of NMDA receptor [1].</p>Formule :C13H9F3N2O3SCouleur et forme :SolidMasse moléculaire :330.28P2X3 antagonist 34
CAS :<p>Potent P2X3 antagonist 34, oral, selective for human, rat, guinea pig receptors; IC50s: 25/92/126 nM; strong anti-tussive, no taste change.</p>Formule :C24H26F2N4O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :456.48ML-252 hydrochloride
CAS :<p>ML-252 is a potent, selective inhibitor of the Kv7.2 voltage-gated potassium channel, demonstrating an IC50 value of 69 nM in patch clamp assays. It exists as the (S)-enantiomer, which is significantly more effective than both its (R)-enantiomer counterpart and the racemic mixture, with respective IC50 values of 944 nM and 160 nM. ML-252 exhibits high selectivity for Kv7.2 over other potassium channel subtypes and shows minimal activity against more than 68 G protein-coupled receptors, various transporters, L- and N-type calcium channels, K_ATP, and hERG potassium channels. However, it does inhibit the melatonin MT1 receptor by 61% at a 10 µM concentration.</p>Formule :C20H24N2OHClCouleur et forme :SolidMasse moléculaire :344.9Licostinel
CAS :<p>Licostinel (CGP 63446) is a glutamate receptor antagonist. Licostinel protects against permanent focal cerebral ischemia.</p>Formule :C8H3Cl2N3O4Degré de pureté :98.02%Couleur et forme :SolidMasse moléculaire :276.033′-Acetate-ATP
CAS :<p>3’-Acetate-ATP, an analogue of ATP and its acetylation product, exhibits maximum ultraviolet absorption at 259 nm in neutral aqueous solutions.</p>Formule :C12H18N5O14P3Couleur et forme :SolidMasse moléculaire :549.22GMA-839
CAS :<p>GMA-839 is a selective modulator of gamma-aminobutyric acid(A) receptors.</p>Formule :C21H31F3O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :388.46Biricodar
CAS :<p>Biricodar is a P-glycoprotein and MRP-1 modulator.</p>Formule :C34H41N3O7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :603.71ADX71441
CAS :<p>ADX71441, a GABAB PAM, lengthens urinary latencies, lessens events & volume, and may aid in alcoholism and bladder pain.</p>Formule :C19H15ClF2N4O4Couleur et forme :SolidMasse moléculaire :436.8Cavα2δ1&NET-IN-3
CAS :<p>Cavα2δ1&NET-IN-3 (example 216) is an inhibitor targeting both the α2δ subunit of voltage-gated calcium channels (VGCC) and the noradrenaline transporter (NET).</p>Formule :C24H30N6O2SCouleur et forme :SolidMasse moléculaire :466.6p-fin4
CAS :<p>p-fin4, a peptide, inhibits STEP-GluA2 interaction, Ki 0.4 μM; may enhance cognition, has anxiolytic and antidepressant effects.</p>Formule :C39H53N8O18PCouleur et forme :SolidMasse moléculaire :952.85Adipiplon
CAS :<p>Adipiplon(NG2-73, NG273) is a novel selective gamma-aminobutyric acid (GABA) partial agonist.</p>Formule :C18H18FN7Couleur et forme :SolidMasse moléculaire :351.38CGP 64213
CAS :<p>CGP 64213 is a GABAb receptor agonist.</p>Formule :C26H36IN2O7PDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :646.45PF-06456384
CAS :<p>PF-06456384 is a highly potent and selective NaV1.7 inhibitor with IC50 value of 0.01 nM.</p>Formule :C35H32F3N7O3S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :719.8AGN-201904Z
CAS :<p>AGN-201904Z is a slow-release, acid-resistant pro-PPI that turns into omeprazole, offering extended acid suppression.</p>Formule :C25H25N3NaO8S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :582.6VU6007477
CAS :<p>VU6007477: M1 PAM, EC50=230 nM, min. agonist activity, penetrates CNS, no seizure AEs.</p>Formule :C24H26N6O2Couleur et forme :SolidMasse moléculaire :430.5AR-C141990
CAS :<p>AR-C141990 is a lactate transporters inhibitor.</p>Formule :C26H28N4O4SCouleur et forme :SolidMasse moléculaire :492.59Piprofurol
CAS :<p>Piprofurol is used as a Calcium channel blocker.</p>Formule :C26H33NO6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :455.54(Rac)-AMG8379
CAS :<p>(Rac)-AMG8379 ((Rac)-AMG8380) is a racemate of AMG8379 which is an orally active and selective sulfonamide NaV1.7 antagonist.</p>Formule :C25H16ClF2N3O5SDegré de pureté :99.6%Couleur et forme :SolidMasse moléculaire :543.93Nepaprazole
CAS :<p>Nepaprazole (TY-11345) is a potent proton pump inhibitor; IC50: 5.8µM at pH 6.0, 9.9µM at pH 7.4. Better inhibition in weak acid.</p>Formule :C18H19N3O2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :341.43RS 5773
CAS :<p>RS 5773 is a benzothiazepine derivative with antianginal effects.</p>Formule :C29H33ClN2O4SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :541.1JT010
CAS :<p>JT010 is an effective agonist of TRPA1 (EC50 = 0.65 nM).</p>Formule :C16H19ClN2O3SDegré de pureté :99.75%Couleur et forme :SolidMasse moléculaire :354.85BTG 502
CAS :<p>BTG 502 is an alkylamide insecticide that binds to voltage-gated sodium channels, antagonising the activation of sodium channels by Batrachotoxin (BTX).</p>Formule :C21H24BrNODegré de pureté :99.30%Couleur et forme :SolidMasse moléculaire :386.33TROX-1
CAS :<p>TROX-1 is the activation state-dependent Cav2 channel antagonist.</p>Formule :C22H16ClFN6ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :434.85Dasolampanel etibutil
CAS :<p>Dasolampanel etibutil is a novel selective antagonist of ionotropic glutamate receptor 5 (iGluR5).</p>Formule :C23H32ClN5O3Couleur et forme :SolidMasse moléculaire :461.98U 89843A
CAS :<p>U 89843A is a positive allosteric modulator of gamma-aminobutyric acid (GABA)A receptors.</p>Formule :C16H23N5Degré de pureté :99.62%Couleur et forme :SolidMasse moléculaire :285.39(R)-3,4-DCPG
CAS :<p>AMPA receptor antagonist with weak activity at NMDA receptors and little activity at kainate receptors</p>Formule :C10H9NO6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :239.18JM-1232
CAS :<p>JM-1232 is a sedative and hypnotic drug being researched as a potential anesthetic.</p>Formule :C24H27N3O2Couleur et forme :SolidMasse moléculaire :389.49Afizagabar
CAS :<p>Afizagabar, a first-in-class α5-GABAAR antagonist, IC50: 585 nM, Ki: 66 nM, may boost memory.</p>Formule :C19H12FN3O2SCouleur et forme :SolidMasse moléculaire :365.38CGP-54626 free base
CAS :<p>CGP-54626 is a selective antagonist of the GABAB receptor (IC50 = 4 nM ).</p>Formule :C18H28Cl2NO3PDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :408.3CFTR corrector 12
CAS :<p>CFTR corrector 12 is a CFTR corrector that rescues all mutant proteins except M760R ABCA3 and can be used to study cystic fibrosis.</p>Formule :C19H21ClN4O2S2Degré de pureté :99.47%Couleur et forme :SolidMasse moléculaire :436.98M084 hydrochloride
CAS :<p>M084 hydrochloride, a TRPC4/5 channel blocker, exhibits IC50 values of 10.3 μM and 8.2 μM, respectively. This compound is noted for its antidepressant and anxiolytic effects [1] [2].</p>Formule :C11H16ClN3Couleur et forme :SolidMasse moléculaire :225.72PPADS tetrasodium
CAS :<p>PPADS tetrasodiuma is a P2X receptor antagonist and an inhibitor of the inverse mode of Na/Ca²⁺ exchange in guinea pig airway smooth muscle.</p>Formule :C14H10N3Na4O12PS2Degré de pureté :95% - ≥95%Couleur et forme :SolidMasse moléculaire :599.3NaPi2b-IN-2
CAS :<p>NaPi2b-IN-2 (compound 5) serves as a potent inhibitor of the sodium-dependent transport protein 2b (SLC34A2, NaPi2b), exhibiting an IC50 of 38 nM against human</p>Formule :C41H47ClF3N5O5SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :814.36Crobenetine hydrochloride
CAS :<p>Crobenetine hydrochloride, a sodium channel antagonist, is used potentially for the treatment of stroke.</p>Formule :C25H34ClNO2Couleur et forme :SolidMasse moléculaire :416CGP 55845 hydrochloride
CAS :<p>CGP55845 hydrochloride is a potent and selective GABAB receptor antagonist with an IC 50 of 6 nM which can be used in neurological research [1] [2].</p>Formule :C18H23Cl3NO3PCouleur et forme :SolidMasse moléculaire :438.71XR9051 Hydrochloride
CAS :<p>XR9051 Hydrochloride, a potent modulator of P-glycoprotein-mediated multidrug resistance (MDR), inhibits the binding of cytotoxics to P-glycoprotein.</p>Formule :C39H39ClN4O5Couleur et forme :SolidMasse moléculaire :679.21α,β-Methylene ATP trisodium
CAS :<p>α,β-Methylene ATP trisodium is a ligand of P2X3 and P2X7 receptor.</p>Formule :C11H15N5Na3O12P3Degré de pureté :99.66%Couleur et forme :SolidMasse moléculaire :571.15Dimethylamiloride
CAS :<p>Dimethylamiloride is a specific inhibitor of antiporters [1].</p>Formule :C8H12ClN7ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :257.68PF-05105679
CAS :<p>PF-05105679 is a selective TRPM8 antagonist (IC50 = 103 nM). PF-05105679 can be used in research on cold-related pain.</p>Formule :C26H21FN2O3Degré de pureté :99.84%Couleur et forme :SolidMasse moléculaire :428.45L 691121
CAS :<p>L 691121 is a class III antiarrhythmic compound. It also blocks potassium currents.</p>Formule :C22H25ClN4O5SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :492.98mGAT-IN-1
CAS :<p>mGAT-IN-1 is a potent, non-selective GAT inhibitor that inhibits mGAT3 activity well (IC50: 2.5 μM, pIC50: 5.61).</p>Formule :C28H34ClN3O2S2Couleur et forme :SolidMasse moléculaire :544.17Risevistinel
CAS :<p>Risevistinel (NYX-783), a positive allosteric modulator of the N-methyl-D-aspartate (NMDA) receptor, may mitigate cognitive deficits in neurodegenerative</p>Formule :C14H23N3O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :297.35LOE 908 hydrochloride
CAS :<p>Broad spectrum cation channel blocker</p>Formule :C41H49ClN2O9Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :749.29Piperidine-4-sulfonic acid
CAS :<p>Piperidine-4-sulfonic acid is a potent GABA agonist, demonstrating an IC50 value of 0.034 μM for the inhibition of H-GABA binding [1].</p>Formule :C5H11NO3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :165.21NPEC-caged-(S)-AMPA
CAS :<p>AMPA receptor agonist</p>Formule :C16H17N3O8Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :379.32Sodium Channel inhibitor 4
CAS :<p>Sodium Channel Inhibitor 4 is a compound that functions as a sodium channel inhibitor [1].</p>Formule :C19H18ClN3O4S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :451.95ZM 260384
CAS :<p>ZM 260384 is a potassium channel opener.</p>Formule :C15H11F4N3O4Couleur et forme :SolidMasse moléculaire :373.26NCS-382 sodium
CAS :<p>NCS-382 (sodium) is a potent antagonist of the GABA receptor, exhibiting anti-sedative and anti-hypnotic properties, with applications in neurological disease</p>Formule :C13H13NaO3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :240.23CGP 54626 hydrochloride
CAS :<p>CGP 54626 hydrochloride is a GABAB receptor antagonist.</p>Formule :C18H29Cl3NO3PDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :444.76S-Pantoprazole sodium trihydrate
CAS :<p>S-Pantoprazole (sodium trihydrate), a variant of Pantoprazole, is pivotal in managing diseases associated with gastric acid secretion disorders, serving as a</p>Formule :C16H20F2N3NaO7SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :459.4TRPV2-selective blocker 1
CAS :<p>TRPV2-selective blocker 1 (compound IV2-1) is a selective inhibitor of the TRPV2 channel, exhibiting an IC50 value of 6.3 μM.</p>Formule :C15H18OS2Couleur et forme :SolidMasse moléculaire :278.43CP-409092
CAS :<p>CP-409092 is a partial GABAA receptor agonist. It has anti-anxiety activity.</p>Formule :C17H19N3O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :297.35Aneratrigine
CAS :<p>Aneratrigine is a blocker of the sodium channel protein type 9 subunit alpha, utilized in research on neuropathic pain diseases [1].</p>Formule :C19H20ClF2N5O2S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :487.97(R)-Elexacaftor
CAS :<p>(R)-Elexacaftor (compound 37) is the enantiomer of Elexacaftor (compound 1). (R)-Elexacaftor is a CFTR modulator with an EC50 of 0.29 μM for CFTR dF508.</p>Formule :C26H34F3N7O4SDegré de pureté :98.991%Couleur et forme :SolidMasse moléculaire :597.65SCS
CAS :<p>SCS is a GABAA receptor antagonist.</p>Formule :C14H12N2O3Degré de pureté :99.73%Couleur et forme :SolidMasse moléculaire :256.26KVI-020
CAS :<p>KVI-020: oral Kv1.5 blocker (IC50: 480nM), hERG inhibitor (IC50: 15100nM), potent antiarrhythmic for AF studies.</p>Formule :C20H25N3O5SCouleur et forme :SolidMasse moléculaire :419.49Chromanol 293B
CAS :<p>slow delayed rectifier K+ current (IKs) blocker</p>Formule :C15H20N2O4SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :324.4GDC-0310
CAS :<p>GDC-0310 is a selective, orally available Nav1.7 inhibitor with an IC50 of 0.6 nM for human Nav1.7, suitable for pain research.</p>Formule :C25H29Cl2FN2O4SDegré de pureté :99.877%Couleur et forme :SolidMasse moléculaire :543.48GNE-0723
CAS :<p>GNE-0723 is a selective positive allosteric modulator of the NMDA receptor, GluN2A.blood-brain barrier (BBB) and Dravet syndrome and Alzheimer's disease (AD).</p>Formule :C16H8ClF6N5OSDegré de pureté :97.29% - 99.91%Couleur et forme :SolidMasse moléculaire :467.78PF-4778574
CAS :<p>PF-4778574 is a positive AMPA receptor allosteric modulation (EC50: 45 to 919 nM in different cells).</p>Formule :C19H22N2O3S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :390.52Mioflazine
CAS :<p>Mioflazine suppresses nucleoside uptake. Mioflazine is an orally active nucleoside transport inhibitor. It has the potential for sleep disorders treatment.</p>Formule :C29H30Cl2F2N4O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :575.48DPO-1
CAS :<p>DPO-1 可以高效抑制电压门控钾离子通道Kv1.5，也可以阻断超快速延迟整流钾电流。它能够预防房性心律失常。</p>Formule :C22H29OPDegré de pureté :99.78%Couleur et forme :SolidMasse moléculaire :340.44CLP257
CAS :<p>CLP257 is a selective K+-Cl− cotransporter KCC2 activator (EC50: 616 nM) and it is inactive against NKCC1, GABAA receptors, KCC1, KCC3 or KCC4.</p>Formule :C14H14FN3O2SDegré de pureté :99.5%Couleur et forme :SolidMasse moléculaire :307.348-Pcpt-cGMP
CAS :<p>8-Pcpt-cGMP acts as an agonist for cyclic nucleotide-gated (CNG) channels with an EC50 of 0.5 μM and exhibits good membrane permeability. This compound is utilized in research to explore the role of CNG channels in visual and olfactory signal transduction.</p>Formule :C16H15ClN5O7PSCouleur et forme :SolidMasse moléculaire :487.81BMS-199264 hydrochloride
CAS :<p>BMS-199264 hydrochloride is selective inhibitor of mitochondrial F1F0 ATP hydrolase,inhibit decline of ATP and myocardial necrosis during myocardial ischemia.</p>Formule :C26H32Cl2N4O4SDegré de pureté :99.86%Couleur et forme :SolidMasse moléculaire :567.53Co 102862
CAS :<p>Co 102862 is a voltage-gated sodium channel blocker. Co 102862 can be used for anticonvulsant studies.</p>Formule :C14H12FN3O2Degré de pureté :99.82%Couleur et forme :SolidMasse moléculaire :273.26Mesendogen
CAS :<p>Mesendogen is an inhibitor of transient receptor potential cation channel, subfamily M, member 6 (TRPM6) and 7 (TRPM7) and acts by inhibiting TRPM6/TRPM7</p>Formule :C18H16ClF3N2OSDegré de pureté :99.66%Couleur et forme :SolidMasse moléculaire :400.85GSK3395879
CAS :<p>GSK3395879 is a selective and orally bioavailable antagonist of transient receptor potential vanilloid-4 (TRPV4) (IC50: 1 nM for hTRPV4).</p>Formule :C20H15F4N3O5SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :485.41BPO-27 racemate
CAS :<p>BPO-27 racemate (BPO-27 (racemate)) is an effective CFTR inhibitor with IC50 of 8 nM.</p>Formule :C26H18BrN3O6Degré de pureté :97.67% - 98.86%Couleur et forme :SolidMasse moléculaire :548.34LG 83-6-05
CAS :<p>LG 83-6-05 is a novel kind of sodium channel blocking agent.</p>Formule :C21H30ClNO3SCouleur et forme :SolidMasse moléculaire :411.99Sudoterb free base
CAS :<p>Sudoterb free base (Sudoterb) , also known as LL3858, is an anti-tubercular drug candidate.</p>Formule :C29H28F3N5ODegré de pureté :97.26% - 98.85%Couleur et forme :SolidMasse moléculaire :519.56URAT1 inhibitor 1
CAS :<p>URAT1 inhibitor 1 (1g) is an inhibitor of uric acid transporter 1 (URAT1) (IC50: 32 nM), has the potential to treat hyperuricemia associated with gout.</p>Formule :C19H15Br2N5O2S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :569.29Clobutinol hydrochloride
CAS :<p>Clobutinol hydrochloride, an antitussive agent, influences heart rate and blood pressure, and is utilized in cough-related research [1] [2] [3].</p>Formule :C14H23Cl2NODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :292.25Xeniafaraunol A
CAS :<p>Xeniafaraunol A (compound 31) is a potent inhibitor of the transient receptor potential melastatin 7 (TRPM7) channel [1].</p>Formule :C20H28O2Couleur et forme :SolidMasse moléculaire :300.44
