Transporteur membranaire/Canal ionique
Les inhibiteurs des transporteurs membranaires et des canaux ioniques sont des composés qui bloquent la fonction des protéines responsables du transport des ions, des nutriments et d'autres molécules à travers les membranes cellulaires. Ces inhibiteurs sont essentiels pour étudier la régulation de l'homéostasie cellulaire, la transduction des signaux et la neurotransmission. Les inhibiteurs des transporteurs membranaires et des canaux ioniques sont également importants pour développer des traitements contre des troubles tels que l'épilepsie, les maladies cardiovasculaires et les syndromes métaboliques. Chez CymitQuimica, nous offrons une sélection diversifiée d'inhibiteurs de haute qualité des transporteurs membranaires et des canaux ioniques pour soutenir vos recherches en physiologie, neurosciences et pharmacologie.
Sous-catégories appartenant à la catégorie "Transporteur membranaire/Canal ionique"
- ABC(3 produits)
- ATPase(93 produits)
- Récepteur de l'adiponectine(5 produits)
- CFTR(64 produits)
- Récepteur CGRP(51 produits)
- Canal calcique(493 produits)
- Canal chlorure(49 produits)
- Récepteur GABA(336 produits)
- Transporteur de monoamine(23 produits)
- Transporteur de monocarboxylate(17 produits)
- NKCC(2 produits)
- NPC1L1(3 produits)
- Cotransporteur Na-K-Cl(8 produits)
- OAT(27 produits)
- OCT(7 produits)
- P-gp(53 produits)
- Canal potassique(276 produits)
- Pompe à protons(39 produits)
- SGLT(30 produits)
- Canal sodique(202 produits)
- Canal TRP/TRPV(92 produits)
Affichez 13 plus de sous-catégories
2270 produits trouvés pour "Transporteur membranaire/Canal ionique"
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UK-59811 hydrochloride
CAS :<p>UK-59811 hydrochloride, Br-dihydropyridine derivative, blocks Ca V Ab channels in bacteria, IC50: 194 nM.</p>Formule :C22H30BrClN2O5Couleur et forme :SolidMasse moléculaire :517.85ω-Conotoxin MVIIC TFA
<p>ω-Conotoxin MVIIC TFA is a peptide and neurotoxin blocks P-type and q-type voltage-sensitive neuronal Ca ++ channels (VGCCs) radiolabel immunoprecipitation.</p>Formule :C106H178N40O32S7·C2HF3O2Couleur et forme :SolidMasse moléculaire :2863.27Agitoxin-2
CAS :<p>Potent Shaker K+ channel blocker (Ki = 0.64 nM). Also inhibits Kv1.3, Kv1.6 and Kv1.1 K+ channels (Ki values are 4, 37 and 44 pM respectively).</p>Formule :C169H278N54O48S8Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :4090.87FD 12-9
CAS :<p>FD 12-9, Anti-glioblastoma activity. is a flavonoid dimer, acts as a dual inhibitor of P-gp and BCRP, with EC50s of 285 nM and 0.9 nM, respectively.</p>Formule :C51H47N3O11Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :877.93Emamectin B1a
CAS :<p>Emamectin B1a can be used in relevant research in the life sciences. Its product number is T37663 and CAS number is 121124-29-6.</p>Formule :C49H75NO13Couleur et forme :SolidMasse moléculaire :886.133Cyclocreatine
CAS :<p>Cyclocreatine, a creatine analogue and substrate for creatine kinase, inhibits creatine metabolism and prostate cancer cell proliferation.</p>Formule :C5H9N3O2Degré de pureté :99.864%Couleur et forme :SolidMasse moléculaire :143.14Apamin
CAS :<p>Apamin: 18-amino acid bee venom peptide, blocks SK channels, anti-inflammatory, anti-fibrotic, strongly basic.</p>Formule :C79H131N31O24S4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :2027.34Caloxin 2A1 acetate
<p>Caloxin 2A1 acetate is an inhibitor of extracellular plasma membrane Ca2+-ATPase (PMCA) peptide.</p>Formule :C66H95N19O24Degré de pureté :98.2%Couleur et forme :SolidMasse moléculaire :1538.57PptT-IN-4
<p>PptT-IN-4 (Compound 3a) is a PptT inhibitor exhibiting an IC50 of 0.71 μM.</p>Formule :C17H23N3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :269.38Mambalgin 1
CAS :<p>ASIC1a inhibitor; IC50: 192 nM (human), 72 nM (dimer); inactive channel binding; selective; pain response delay.</p>Formule :C272H429N85O84S10Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :6554.51TRPA1 Antagonist 3
CAS :<p>TRPA1 Antagonist 3 is a compound with photoswitchable properties that acts as an agonist on the TRPA1 channel, providing the ability for optical control.</p>Formule :C11H8ClN3Couleur et forme :SolidMasse moléculaire :217.66Atagabalin
CAS :<p>Atagabalin (PD 0200390), a gabamimetic for insomnia treatment and related to gabapentin, was halted due to poor trial outcomes.</p>Formule :C10H19NO2Couleur et forme :SolidMasse moléculaire :185.26P-gp inhibitor 15
<p>P-gp Inhibitor 15 (compound 7a), a nonsubstrate inhibitor of P-glycoprotein (Pgp), inhibits Pgp-ATPase activity and interferes with Pgp-mediated Rhodamine123</p>Formule :C35H60N2O4Couleur et forme :SolidMasse moléculaire :572.86(Iso)-Atagabalin HCl
CAS :<p>(Iso)-Atagabalin HCl(isomer-Atagabalin HCl) is an alpha -2- delta ligand that can be used to treat non-restorative sleep.</p>Formule :C10H20ClNO2Degré de pureté :99.26% - >99.99%Couleur et forme :SoildMasse moléculaire :221.72Roquefortine C
CAS :<p>Roquefortine C is a fungal cyclopeptide isolated from Penicillium roquefortii, activates P-gp and also inhibits P450-3A and other haemoproteins</p>Formule :C22H23N5O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :389.45Carbonic anhydrase inhibitor 32
<p>Carbonic anhydrase inhibitor32 (compound 5B) is an orally active, selective inhibitor of hCA (carbonic anhydrase) II/VII, with Ki values of 6.3 nM for hCA II, 10.1 nM for hCA VII, and 681 nM for hCA I. It shows potential for neuroprotection and anticonvulsant effects by reducing mTOR activation and increasing hippocampal KCC2 levels.</p>Formule :C17H16N6O3SCouleur et forme :SolidMasse moléculaire :384.41AQP4 (201-220)
CAS :<p>AQP4 (201-220) is the encephalitogenic epitope of AQP-4. AQP4 (201-220) can induce experimental autoimmune encephalomyelitis (EAE), characterized by midline brain lesions, retinal lesions, and lesions at the gray matter/white matter boundary of the spinal cord. AQP-4 is the target antigen in neuromyelitis optica.</p>Formule :C97H143N27O27SCouleur et forme :SolidMasse moléculaire :2151.4Cavα2δ-IN-1
CAS :<p>Cavα2δ-IN-1 demonstrates exceptional specificity for voltage-gated calcium channels Cavα2δ-1 (with a Ki value of 6 nM), in comparison to Cavα2δ-2 (with a Ki</p>Formule :C18H27N5OCouleur et forme :SolidMasse moléculaire :329.448LU-32-176B
CAS :<p>LU32-176B is a bioactive chemical.</p>Formule :C23H24F2N2O2Couleur et forme :SolidMasse moléculaire :398.45EVT-401
<p>EVT-401 (P2X7 receptor antagonist-1), a purinergic P2X7 receptor antagonist, demonstrates efficacy in combating neuroinflammation [1].</p>Formule :C22H20F4N2O3Couleur et forme :SolidMasse moléculaire :436.43-Aminopropylphosphinic acid
CAS :<p>3-Aminopropylphosphinic acid (3-APPA) is a phosphonic analog of gamma-aminobutyric acid (GABA).</p>Formule :C3H10NO2PCouleur et forme :SolidMasse moléculaire :123.092D-myo-Inositol-1,3-diphosphate (sodium salt)
CAS :<p>D-myo-Inositol-1,3-phosphate (Ins(1,3)P) is an inositol phosphate involved in cellular signal transduction.</p>Formule :C6H12Na2O12P2Couleur et forme :SolidMasse moléculaire :384.08(-)-(S)-Cibenzoline
CAS :<p>Cibenzoline, also known as Escibenzoline, is the S(+)-enantiomer of Cibenzoline and functions as an antiarrhythmic agent.</p>Formule :C18H18N2Couleur et forme :SolidMasse moléculaire :262.35Apamin acetate
<p>Apamin acetate: Selective Ca2+-activated K+ channel blocker, 18-amino acid bee venom peptide, promotes synapse repair, anti-inflammatory.</p>Degré de pureté :96.97%Couleur et forme :SolidElgodipine
CAS :<p>Elgodipine decreases angina severity, inhibits muscle growth, and is voltage-sensitive, showing promise for angina treatment.</p>Formule :C29H33FN2O6Degré de pureté :98.95% - 99.50%Couleur et forme :SolidMasse moléculaire :524.58GsMTx4
CAS :<p>GsMTx-4, mechanosensitive and stretch-activated ion channel inhibitor (CAS 1209500-46-8).</p>Formule :C185H273N49O45S6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :4095.84Conantokin-R
CAS :<p>Conantokin-R is an NMDA receptor peptide antagonist (IC50=93 nM); Conantokin-R exhibits anticonvulsant activity; Conantokin-R binds Zn2+ and Mg2+ (Kds 0.15 μM</p>Formule :C127H201N35O49S3Couleur et forme :SolidMasse moléculaire :3098.38Isotachysterol 3
CAS :<p>Isotachysterol 3 boosts calcium transport in gut and bone mobilization in kidneyless rats.</p>Formule :C27H44OCouleur et forme :SolidMasse moléculaire :384.64AVLX-125
CAS :<p>AVLX-125 (UCCB01-125), a potent inhibitor of PSD-95 and PDZ domains, exhibits a dissociation constant (Kd) of 10 nM. It is utilized in researching inflammatory pain [1] [2].</p>Formule :C62H104N10O29Couleur et forme :SolidMasse moléculaire :1453.54S-Sulfo-L-cysteine sodium salt
CAS :<p>S-Sulfo-L-cysteine sodium salt shows a weak affinity for mGluR1α and mGluR5a at high concentrations and has potential antioxidant activity.</p>Formule :C3H6NNaO5S2Degré de pureté :99.88%Couleur et forme :SolidMasse moléculaire :223.2Oleoyl Serotonin
CAS :<p>Oleoyl Serotonin is an antagonist of hTRPV1 with an IC50 of 2.57 μM.</p>Formule :C28H44N2O2Degré de pureté :99.88%Couleur et forme :SolidMasse moléculaire :440.666,7-dimethylisatin
CAS :<p>6,7-Dimethylisatin (6,7-dimethyl-1H-indole-2,3-dione) inhibits hGAT3 with IC50 of 108 μM. 6,7-Dimethylisatin also inhibits hBGT1, hGAT2.</p>Formule :C10H9NO2Degré de pureté :98.98%Couleur et forme :SolidMasse moléculaire :175.18URAT1 inhibitor 11
CAS :<p>URAT1 inhibitor11 (Compound 7) is a potent URAT1 inhibitor, exhibiting an IC50 of 0.18 μM. It effectively reduces uric acid levels in zebrafish with hyperuricemia induced by Potassium oxonate and Xanthinesodium salt.</p>Formule :C20H16F4N2O2Couleur et forme :SolidMasse moléculaire :392.35μ-Conotoxin SxIIIC
<p>μ-Conotoxin SxIIIC, an irreversible NaV channel inhibitor, is derived from Conus striolatus and is useful in researching neurological disorders, including</p>Formule :C90H142N42O27S6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :2436.75Cevadine
<p>Cevadine is a natural product that can be used as a reference standard.</p>Formule :C32H49NO9Couleur et forme :SolidMasse moléculaire :591.742δ-Theraphotoxin-Hm1a toxin
<p>δ-Theraphotoxin-Hm1a is a selective NaV1.1 activator that induces pain and touch sensitivity, with potential applications in irritable bowel syndrome research [</p>Formule :C170H240N48O53S6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :3996.4Sulcardine 2HCl
CAS :<p>Sulcardine 2HCl is a multi-ion channel blocker that blocks the properties of hERG and hNav1.5 channels and can be used to study atrial fibrillation.</p>Formule :C24H35Cl2N3O4SDegré de pureté :99.33% - 99.76%Couleur et forme :SoildMasse moléculaire :532.523AChE/Aβ-IN-1
<p>AChE/Aβ-IN-1 (compound 32) is a potent, orally active acetylcholinesterase (AChE) inhibitor with an IC50 of 86 nM and an NMDA receptor antagonist targeting the</p>Formule :C20H25BrN4Couleur et forme :SolidMasse moléculaire :401.34GpTx-1
CAS :<p>GpTx-1 exhibits potent selectivity as a NaV1.7 antagonist, demonstrating an inhibition concentration (IC50) of 10 nM [1].</p>Formule :C176H271N53O45S7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :4073.82Heteropodatoxin-1
<p>Heteropodatoxin-1 (HpTx1), a spider peptide toxin, acts as an inhibitor of the Kv4.2 current, while concurrently inhibiting Nav1.7 and activating Nav1.9</p>Formule :C168H238N46O51S6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :3910.35(S)-PF-03716556
CAS :<p>(S)-PF-03716556 can be used as an acid pump inhibitor for the treatment of disease conditions mediated by acid pump inhibitory activity.</p>Formule :C22H26N4O3Degré de pureté :99.8% - 99.91%Couleur et forme :SoildMasse moléculaire :394.47GYKI-47261 dihydrochloride
CAS :<p>GYKI-47261 dihydrochloride is an AMPA receptor antagonist and CYP2E1 inducer, demonstrating broad-spectrum anticonvulsant and neuroprotective activities.</p>Formule :C18H17Cl3N4Degré de pureté :98.32% - 99.14%Couleur et forme :SolidMasse moléculaire :395.71Antidepressant agent 4
<p>Antidepressant agent 4: orally active, has antidepressant, anxiolytic, and nootropic effects.</p>Formule :C19H38ClN5O2SCouleur et forme :SolidMasse moléculaire :436.06Astressin 2B
CAS :<p>CRF2 antagonist with IC50 of 1.3 nM; >500 nM for CRF1. Aids gastric emptying.</p>Formule :C183H307N49O53Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :4041.69Nicardipine-d3 hydrochloride
CAS :<p>Nicardipine D3 hydrochloride is the deuterium labeled Nicardipine hydrochloride.</p>Formule :C26H30ClN3O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :519Halofantrine hydrochloride
CAS :<p>Halofantrine hydrochloride (SKF-102886) is an orally administered antimalarial drug effective against drug-resistant P. falciparum and P. vivax. SKF-102886 has cardiac toxicity, inhibiting hERG and delayed rectifier potassium channel I Kr, leading to prolonged QTc and PR intervals.</p>Formule :C26H31Cl3F3NODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :536.89(S)-Nicardipine
CAS :<p>(S)-Nicardipine is the less active S enantiomer of Nicardipine. Nicardipine is a blocker of calcium channel(IC50 of 1 μM for blocking cardiac calcium channels).</p>Formule :C26H29N3O6Couleur et forme :SolidMasse moléculaire :479.53Lubiprostone hemiketal
CAS :<p>Lubiprostone (hemiketal) (RU-0211 (hemiketal)), a selective activator of the chloride channel 2 (CLCN2), facilitates the treatment of chronic idiopathic constipation and opioid-induced constipation. It functions by enhancing CLCN2 channel activity, which boosts chloride ion secretion in the intestines, subsequently increasing fluid secretion and improving intestinal peristalsis. Additionally, Lubiprostone (hemiketal) may be utilized in research related to chronic constipation and cancer.</p>Formule :C20H32F2O5Couleur et forme :SolidMasse moléculaire :390.46Ethacizine hydrochloride
CAS :<p>Ethacizine hydrochloride (NIK-244) has antiarrhythmic activity and can be used to study arrhythmias and myocardial infarction.</p>Formule :C22H28ClN3O3SDegré de pureté :98.08% - 98.08%Couleur et forme :SolidMasse moléculaire :449.99MRK-016
CAS :<p>MRK-016 is a selective GABAA α5 receptor inverse agonist/ negative allosteric modulator, orally available and penetrating the BBB. MRK-016 is antidepressant.</p>Formule :C17H20N8O2Degré de pureté :99.76%Couleur et forme :SolidMasse moléculaire :368.39
