Canal TRP/TRPV
Les canaux TRP (récepteur potentiel transitoire), y compris la sous-famille TRPV, sont un groupe de canaux ioniques impliqués dans divers processus sensoriels, tels que la sensation de température, la perception de la douleur et l'osmorégulation. Les canaux TRP sont largement exprimés dans différents tissus et jouent un rôle dans les réponses physiologiques aux stimuli environnementaux. Les canaux TRPV, en particulier, sont impliqués dans la détection des changements de température et sont associés à des conditions telles que la douleur chronique, l'inflammation et le cancer. Chez CymitQuimica, nous proposons une gamme complète de modulateurs de canaux TRP/TRPV pour soutenir vos recherches en biologie sensorielle, gestion de la douleur et transduction du signal.
110 produits trouvés pour "Canal TRP/TRPV".
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Vocacapsaicin hydrochloride
CAS :Vocacapsaicin hydrochloride (CA-008 hydrochloride) is a non-opioid TRPV1 agonist, a raw material for capsaicin, and is used for pain relief.Formule :C26H42ClN3O4Degré de pureté :99.66% - 99.80%Couleur et forme :SolidMasse moléculaire :496.08TRPV4 agonist-1 free base
CAS :TRPV4 agonist-1 free base (OUN67600) is an agonist of transient receptor potential vanilloid 4 (TRPV4;EC50 of 60 nM, in the hTRPV4 Ca2+ assay).Formule :C25H22F2N4O2Degré de pureté :99.79%Couleur et forme :SolidMasse moléculaire :448.46IA-Alkyne
CAS :IA-Alkyne: TRPC agonist, cysteine-reactivity probe, potential in respiratory infection study.Formule :C8H12INODegré de pureté :99.76%Couleur et forme :White SolidMasse moléculaire :265.091Ref: TM-T15543
1mg56,00€1mL*10mM (DMSO)114,00€5mg119,00€10mg177,00€25mg250,00€50mg313,00€100mg432,00€BI-749327
CAS :BI-749327 is a high selectivity and orally bioavailable antagonist of TRPC6 (IC50s: 13 nM, 19 nM and 15 nM for mouse, human and guinea pig TRPC6).Formule :C23H21F3N4O2Degré de pureté :99.68% - 99.84%Couleur et forme :SolidMasse moléculaire :442.43Ref: TM-T10537
1mg126,00€2mg168,00€5mg260,00€1mL*10mM (DMSO)285,00€10mg409,00€25mg597,00€50mg782,00€100mg1.044,00€500mg2.088,00€GFB-8438
CAS :GFB-8438 is a potent and subtype selective inhibitor of TRPC5(IC50s of 0.18 and 0.29 μM of hTRPC5 and hTRPC4, respectively).Formule :C16H14ClF3N4O2Degré de pureté :99.58%Couleur et forme :SolidMasse moléculaire :386.76TRPM8 antagonist 3
CAS :TRPM8 antagonist 3 is a blocker of TRPM8 (IC50 = 11 nM).Formule :C13H12N2O4SDegré de pureté :99.74%Couleur et forme :White SolidMasse moléculaire :292.31(Iso)-TRPV4 antagonist 5
CAS :(Iso)-TRPV4 antagonist 5 are selective oral TRPV4 blockers for pulmonary edema research.Formule :C25H27FN6O3Degré de pureté :99.23% - 99.63%Masse moléculaire :478.52Cyclic ADP-Ribose (ammonium salt)
Cyclic ADP-Ribose (ammonium salt) (cADPR) is an NAD⁺ metabolite that triggers Ca²⁺ release from ER stores via ryanodine receptors, relevant to inflammation research.Formule :C15H21N5O13P2·xNH3Couleur et forme :White SolidCBP-1018
CAS :CBP-1018 is a peptide-drug conjugate (PDC) composed of a dual-targeting ligand for FRα/TRPV6, linked to Monomethylauristatin E. It holds promise for research in the field of breast cancer.Formule :C132H192N30O38SMasse moléculaire :2839.18(S)-ABT 102
CAS :N-[(1S)-1H-inden-1-yl]-N'-indazol-4-ylurea is a strong TRPV1 blocker with a 123 nM IC50 against capsaicin.Formule :C21H24N4ODegré de pureté :99.65% - 99.77%Couleur et forme :White SolidMasse moléculaire :348.44Ref: TM-T29522L
1mg73,00€5mg149,00€1mL*10mM (DMSO)154,00€10mg212,00€25mg319,00€50mg447,00€100mg610,00€200mg822,00€RN-1665
CAS :RN-1665 is a potent and selective TRPV4 receptor antagonist.Formule :C20H24F5N3O3S2Degré de pureté :99.96%Couleur et forme :SoildMasse moléculaire :513.54PF-04745637
CAS :PF-04745637 is a potent and selective TRPA1 antagonist with an IC50 of 17 nM[1].Formule :C27H32ClF3N2O2Degré de pureté :98.39% - 98.88%Couleur et forme :SolidMasse moléculaire :509L-R4W2
CAS :Vanilloid TRPV1 (VR1) receptor antagonist peptide (IC50 ~ 0.1 μM); blocks Ca2+ currents in dorsal root ganglion neurons. Analgesic in vivo.Formule :C46H71N21O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1014.2CBP-1008
CBP-1008 is a dual-ligand peptide-drug conjugate (PDC) with MMAE, targeting folate receptor (FRα) and TRPV6. It exhibits high binding affinity to FRα and low affinity to TRPV6. CBP-1008 shows antitumor activity and can be utilized for research in advanced solid tumors such as colorectal cancer, breast cancer, non-small cell lung cancer, ovarian cancer, adrenocortical carcinoma, and follicular dendritic cell sarcoma.Couleur et forme :Odour SolidResolvin D2
CAS :Resolvin D2 (RvD2) is a TRPV1 inhibitor and pro-ablative mediator with anti-inflammatory, anti-infective and pro-ablative effects.Formule :C22H32O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :376.49TRPV1 antagonist 6
TRPV1 antagonist 6 (compound 51) is a modality-selective TRPV1 antagonist that exhibits antagonistic activity against capsaicin activation with an IC50 of 2.85 nM and demonstrates an inhibition rate of 28.48% against proton activation at a concentration of 3 µM.Formule :C26H28ClN5O3Masse moléculaire :493.18807N-Oleoyl Glutamine
CAS :N-Oleoyl Glutamine (Oleoyl-L-glutamine) antagonizes TRPV1 of the transient receptor potential (TRP) calcium channel.Formule :C23H42N2O4Degré de pureté :99.61%Couleur et forme :SolidMasse moléculaire :410.59Oleoyl Serotonin
CAS :Oleoyl Serotonin is an antagonist of hTRPV1 with an IC50 of 2.57 μM.Formule :C28H44N2O2Degré de pureté :99.88%Couleur et forme :SolidMasse moléculaire :440.66TRPA1-IN-2
CAS :TRPA1-IN-2 is a potent and orally active TRPA1 inhibitor with an IC50 value of 0.04 µM.TRPA1-IN-2 has anti-inflammatory activity.Formule :C24H25F3N4ODegré de pureté :98.93%Couleur et forme :SoildMasse moléculaire :442.48Ref: TM-T77511
1mg56,00€5mg129,00€1mL*10mM (DMSO)142,00€10mg188,00€25mg319,00€50mg447,00€100mg600,00€200mg807,00€N-Oleoyl Valine Ammonium salt
N-Oleoyl Valine Ammonium salt is an N-acyl amide compound that is a TRPV3 antagonist and can be used to study inflammation.Formule :C23H46N2O3Degré de pureté :99.72%Couleur et forme :White SolidMasse moléculaire :398.62
