Canal potassique
Les canaux potassiques sont un groupe diversifié de protéines membranaires qui facilitent le flux des ions potassium (K+) à travers la membrane cellulaire. Ces canaux jouent un rôle crucial dans le maintien du potentiel de membrane au repos, la régulation du volume cellulaire et le contrôle de l'excitabilité des neurones et des cellules musculaires. Les canaux potassiques sont impliqués dans divers processus physiologiques, y compris la régulation du rythme cardiaque, la sécrétion d'insuline et la libération de neurotransmetteurs. La dysrégulation des canaux potassiques est liée à des conditions telles que les arythmies, l'épilepsie et l'hypertension. Chez CymitQuimica, nous proposons une large gamme de modulateurs de canaux potassiques pour soutenir vos recherches en électrophysiologie, santé cardiovasculaire et neurobiologie.
304 produits trouvés pour "Canal potassique"
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Halothane
CAS :Halothane (Anestan) 可以减弱内皮依赖性舒张作用。Formule :C2HBrClF3Degré de pureté :99.80% - >99.99%Couleur et forme :Colorless Volatile Liquid Density 1 875 G / Cm3 Boiling Point 122 4°F (50 2°C) NoncombustibleMasse moléculaire :197.38Ropivacaine
CAS :Ropivacaine (LEA-103 HCl) is a local anaesthetic drug belonging to the amino amide group.Formule :C17H26N2ODegré de pureté :97.75% - >99.99%Couleur et forme :SolidMasse moléculaire :274.40NS5806
CAS :NS5806 activates K+ currents, slows KV4.2/4.3 decay with KChIP2, and boosts KV4.3/KChIP2 peaks (EC50=5.3μM).Formule :C16H8Br2F6N6ODegré de pureté :97.95%Couleur et forme :SolidMasse moléculaire :574.07AZD 7009
CAS :AZD 7009 is a novel antiarrhythmic compound that inhibits the sodium current of hNav1.5 in CHO K1 cells with an IC50 of 11 uM.Formule :C23H34N4O5Degré de pureté :98.42% - 98.51%Couleur et forme :SoildMasse moléculaire :446.54Minoxidil
CAS :Minoxidil (U10858) is an orally administered vasodilator with hair growth stimulatory and antihypertensive effects.Formule :C9H15N5ODegré de pureté :99.885% - >99.99%Couleur et forme :Crystals From Methanol-Acetonitrile SolidMasse moléculaire :209.25BMS-394136
CAS :BMS-394136 (BMS 394136) is a KV1.5 antagonist for the treatment of cardiovascular diseases such as arrhythmias and atrial fibrillation.Formule :C24H21Cl2FN4ODegré de pureté :98.59% - 99.95%Couleur et forme :SolidMasse moléculaire :471.35Bupivacaine hydrochloride
CAS :Bupivacaine hydrochloride (Vivacaine) is a long-lasting, amide local anesthetic that blocks sodium channels, inhibiting nerve impulses and sensation.Formule :C18H28N2O·HClDegré de pureté :99.89% - 99.9%Couleur et forme :SolidMasse moléculaire :324.89DCEBIO
CAS :DCEBIO, a 1-EBIO derivative, enhances Cl- secretion via hIK1 K+ channel and apical conductance in T84 cells.
Formule :C9H8Cl2N2ODegré de pureté :99.89%Couleur et forme :SolidMasse moléculaire :231.08VU591
CAS :VU591 is a selective extra-renal potassium channel inhibitor with an IC₅₀ of 0.24 μM.Formule :C16H12N6O5Degré de pureté :99.29% - 99.53%Couleur et forme :SolidMasse moléculaire :368.3Ref: TM-T13320L
5mg48,00€10mg75,00€25mg133,00€50mg230,00€100mg344,00€500mg740,00€1mL*10mM (DMSO)49,00€4-Aminopyridine
CAS :4-Aminopyridine (Dalfampridine) is a nonselective potassium (K+) channel blocker that binds to the cytoplasmic side of the cell membrane.Formule :C5H6N2Degré de pureté :91.61%Couleur et forme :SolidMasse moléculaire :94.11VU6036720
VU6036720 is a potent and selective inhibitor of the isomeric Kir4.1/5.1.VU6036720 inhibits Kir4.1/5.1 activity by decreasing the channel open-circuit
Formule :C20H22ClFN4O2SDegré de pureté :98.1%Couleur et forme :SoildMasse moléculaire :436.93Tolbutamide
CAS :Tolbutamide (HLS 831) is a sulphonylurea hypoglycemic agent with actions and uses similar to those of CHLORPROPAMIDE.Formule :C12H18N2O3SDegré de pureté :99.80% - 99.93%Couleur et forme :White Crystalline PowderMasse moléculaire :270.35Butamben
CAS :Butamben (Butyl 4-aminobenzoate) is a long-duration local anesthetic used for the treatment of chronic pain.Formule :C11H15NO2Degré de pureté :99.43%Couleur et forme :Crystals From Alc Physical Description Yellow Powder Insoluble In Water (Ntp 1992)Masse moléculaire :193.24Quinine
CAS :Quinine is a natural cinchona alkaloid that has been used for centuries in the prevention and therapy of malaria.Formule :C20H24N2O2Degré de pureté :99.93% - 99.97%Couleur et forme :White Solid PowderMasse moléculaire :324.42Minocycline hydrochloride
CAS :Minocycline HCl: tetracycline antibiotic, treats bacterial infections and acne, may cause acute or chronic hepatitis.Formule :C23H28ClN3O7Degré de pureté :99.28% - >99.99%Couleur et forme :Bright Yellow-Orange Amorphous Solid Crystalline YellowMasse moléculaire :493.94Quinidine hydrochloride monohydrate
CAS :Quinidine hydrochloride monohydrate is an optical isomer of quinine. Quinidine prolongs cellular action potential and decreases automaticity.Formule :C20H27ClN2O3Degré de pureté :94.4% - 99.68%Couleur et forme :SolidMasse moléculaire :378.89NS8593 hydrochloride
CAS :NS8593 hydrochloride (NS8593 HCl) is a potent and selective inhibitor of small conductance Ca2+-activated K+ channels (SK channels) .Formule :C17H18ClN3Degré de pureté :99.77%Couleur et forme :SolidMasse moléculaire :299.8Ref: TM-T12256
1mg43,00€2mg56,00€5mg88,00€10mg150,00€25mg333,00€50mg497,00€100mg717,00€1mL*10mM (DMSO)92,00€Hydrochlorothiazide
CAS :Hydrochlorothiazide (HCTZ) 是一种口服有效的噻嗪类的利尿药，可抑制转化 TGF-β/Smad 信号通路。它通过打开钙激活钾 (KCA) 通道发挥直接的血管松弛作用。它改善心脏功能，减少纤维化并具有降压作用。Formule :C7H8ClN3O4S2Degré de pureté :99.43% - 99.50%Couleur et forme :Crystals Physical Description Crystals Or White Powder (Ntp 1992)Masse moléculaire :297.74NS19504
CAS :NS19504 is an activator of Ca2+-activated K+ channel with EC50 of 11.0 µM.Formule :C10H9BrN2SDegré de pureté :99.87%Couleur et forme :SolidMasse moléculaire :269.16Ref: TM-T12255
5mg50,00€10mg84,00€25mg166,00€50mg280,00€100mg420,00€500mg888,00€1mL*10mM (DMSO)52,00€Cloperastine hydrochloride
CAS :Cloperastine hydrochloride (HT-11 hydrochloride) is a type of flavonoid.Formule :C20H25Cl2NODegré de pureté :97.74% - 99.42%Couleur et forme :SolidMasse moléculaire :366.33Tertiapin-Q
CAS :Tertiapin-Q is a bee toxin derivative that inhibits BK-type K(+) channels in a concentration-dependent manner, inhibiting efflux to K(+).Formule :C106H175N35O24S4Degré de pureté :98.06% - 98.09%Couleur et forme :SolidMasse moléculaire :2452Repaglinide
CAS :Repaglinide, a benzoic acid derivative, stimulates insulin, treats type 2 diabetes, and may rarely cause acute liver injury.Formule :C27H36N2O4Degré de pureté :99.73% - >99.99%Couleur et forme :White To Off-White SolidMasse moléculaire :452.59Linoleoyl glycine
CAS :Linoleoyl glycine activates hKCNQ1/hKCNE1 channels, has analgesic properties, and is found in skin, spinal cord, and brain.
Formule :C20H35NO3Degré de pureté :98.96%Couleur et forme :SolidMasse moléculaire :337.5Topiramate
CAS :Topiramate (RWJ 17021) is a unique antiseizure medication that is used in the treatment of partial and generalized seizures.Formule :C12H21NO8SDegré de pureté :99.79% - 99.92%Couleur et forme :White To Off-White Crystalline PowderMasse moléculaire :339.36Terfenadine
CAS :Terfenadine, metabolized to fexofenadine by CYP3A4, is a non-sedative antihistamine targeting H1 receptors.Formule :C32H41NO2Degré de pureté :98.76% - 99.75%Couleur et forme :SolidMasse moléculaire :471.67BMS-191095
CAS :BMS-191095 is mitochondrial ATP-sensitive potassium (mitoKATP) channel activator.Formule :C22H21ClN4O2Degré de pureté :>99.99%Couleur et forme :SolidMasse moléculaire :408.88Ref: TM-T10566
1mg92,00€5mg192,00€10mg289,00€25mg522,00€50mg708,00€100mg954,00€1mL*10mM (DMSO)212,00€ICA-27243
CAS :ICA-27243: Potent KCNQ2/Q3 opener, oral, EC50 0.38 μM; less effective on KCNQ4, KCNQ3/Q5; antiepileptic.Formule :C12H7ClF2N2ODegré de pureté :99.54%Couleur et forme :SolidMasse moléculaire :268.65VU591 hydrochloride
CAS :VU591 hydrochloride is a selective Kir1.1 (ROMK) blocker with IC50 of 0.24 μM, not affecting Kir7.1, Kir2.1, Kir2.3, or Kir4.1, similar to VU 590.Formule :C16H13ClN6O5Degré de pureté :98.93% - 99.22%Couleur et forme :SolidMasse moléculaire :404.76Ref: TM-T13320
1mg34,00€5mg71,00€10mg105,00€25mg215,00€50mg366,00€100mg512,00€200mg695,00€1mL*10mM (DMSO)79,00€N-Acetylprocainamide
CAS :N-Acetylprocainamide (NAPA), the N-acetylated metabolite of Procainamide, is a Class III antiarrhythmic agent, while procainamide is a Class Ia antiarrhythmicFormule :C15H23N3O2Degré de pureté :99.65% - 99.74%Couleur et forme :SolidMasse moléculaire :277.36Propafenone
CAS :Propafenone: a drug for ventricular arrhythmias with mild beta-blocker activity, prolongs refractory period, and reduces heart automaticity.Formule :C21H27NO3Degré de pureté :99.02%Couleur et forme :SolidMasse moléculaire :341.44Ropivacaine hydrochloride
CAS :Ropivacaine hydrochloride (Ropivacaine monohydrochloride) is the hydrochloride salt of ropivacaine, a local anesthetic of the amide type with analgesic activityFormule :C17H26N2O·HClDegré de pureté :99.85% - 99.95%Couleur et forme :SolidMasse moléculaire :310.86Oxybutynin
CAS :Oxybutynin (Ditropan) is a synthetic anticholinergic agent that is used for treatment of urinary incontinence and overactive bladder syndrome.Formule :C22H31NO3Degré de pureté :97.81% - 99.57%Couleur et forme :White To Off-White Crystalline PowderMasse moléculaire :357.49Gliclazide
CAS :Gliclazide (SE1702), an oral antihyperglycemic agent, belongs to the sulfonylurea class of insulin secretagogues, which act by stimulating beta-cells of theFormule :C15H21N3O3SDegré de pureté :99.58%Couleur et forme :SolidMasse moléculaire :323.41Dequalinium chloride
CAS :Dequalinium chloride: topical bacteriostat, blocks apamin-sensitive K+ channels, used for wounds, oral infections, potential antifungal, risk of skin ulcers.
Formule :C30H40Cl2N4Degré de pureté :99.79% - 99.9%Couleur et forme :SolidMasse moléculaire :527.59Astemizole
CAS :Astemizole (Laridal) is a long-acting antihistamine for allergies like rhinitis and asthma, with fewer anticholinergic effects.Formule :C28H31FN4ODegré de pureté :98.24% - 99.67%Couleur et forme :White Crystals SolidMasse moléculaire :458.57Mefloquine
CAS :Mefloquine (Ro 215998), a quinoline antimalarial agent, is an anti-SARS-CoV-2 entry inhibitor.
Formule :C17H16F6N2ODegré de pureté :99.89%Couleur et forme :SolidMasse moléculaire :378.31Diazoxide
CAS :Diazoxide (Proglycem) is a benzothiadiazine derivative that is a peripheral vasodilator used for hypertensive emergencies.Formule :C8H7ClN2O2SDegré de pureté :99% - 99.83%Couleur et forme :SolidMasse moléculaire :230.67Oxybutynin chloride
CAS :Oxybutynin chloride (Oxybutynin HCl) is an anticholinergic medication used to relieve urinary and bladder difficulties.Formule :C22H32ClNO3Degré de pureté :99.27% - >99.99%Couleur et forme :White PowderMasse moléculaire :393.96Flufenamic acid
CAS :Flufenamic acid (Arlef) is an anthranilic acid derivative with analgesic, anti-inflammatory, and antipyretic properties.Formule :C14H10F3NO2Degré de pureté :98.68%Couleur et forme :White To Light Yellow Crystalline PowderMasse moléculaire :281.23Proflavine Hemisulfate
CAS :Proflavine Hemisulfate (3,6-Diaminoacridine hemisulfate) is the hemisulfate salt of proflavine, an acridine-derived fluorescent contrast and disinfectant agent.Formule :C13H12N3O2S0Degré de pureté :99.55%Couleur et forme :Orange To Red PowderMasse moléculaire :258.291-EBIO
CAS :1-EBIO (1-EBIO) is a calium channel agonist.Formule :C9H10N2ODegré de pureté :98.75%Couleur et forme :SolidMasse moléculaire :162.19Rosuvastatin calcium
CAS :Rosuvastatin calcium (ZD4522) , a selective and competitive inhibitor of hepatic hydroxymethyl-glutaryl coenzyme A (HMG-CoA) reductase, has antilipidemicFormule :(C22H27FN3O6S)CaDegré de pureté :98.21% - 99.68%Couleur et forme :White To Off-White Crystalline SolidMasse moléculaire :1001.14Nicorandil
CAS :Nicorandil (SG-75)(Ikorel) acts by relaxing the smooth muscle of the blood vessels, especially those of the venous system.Formule :C8H9N3O4Degré de pureté :98.14% - >99.99%Couleur et forme :White Or Off-White PowderMasse moléculaire :211.17Disopyramide
CAS :Disopyramide, or Triombrin, a class I anti-arrhythmic with membrane-stabilizing effects, has heart depressant, anticholinergic, and anesthetic properties.Formule :C21H29N3ODegré de pureté :99.62%Couleur et forme :SolidMasse moléculaire :339.47Glipizide
CAS :Glipizide (CP 28720) is a short-acting, second-generation sulfonylurea with hypoglycemic activity.Formule :C21H27N5O4SDegré de pureté :99.67% - 99.75%Couleur et forme :SolidMasse moléculaire :445.54Indapamide
CAS :Indapamide (Noranat) is a non-thiazide sulphonamide diuretic compound, generally used in the treatment of hypertension, as well as decompensated cardiac failure.Formule :C16H16ClN3O3SDegré de pureté :98.97% - 99.83%Couleur et forme :SolidMasse moléculaire :365.83Linopirdine
CAS :Linopirdine (DuP 996) is a TRPV1 agonist.Formule :C26H21N3ODegré de pureté :99.45% - 99.78%Couleur et forme :SolidMasse moléculaire :391.46Ref: TM-T15758
1mg40,00€2mg52,00€5mg84,00€10mg119,00€25mg215,00€50mg371,00€100mg532,00€200mg767,00€500mg1.144,00€1mL*10mM (DMSO)93,00€NS3623
CAS :NS3623 is an activator of human ether-a-go-go-related gene potassium channels.Formule :C15H10BrF3N6ODegré de pureté :97.06%Couleur et forme :SolidMasse moléculaire :427.18Tipepidine hydrochloride
CAS :Tipepidine hydrochloride: reversible DA D2 receptor inhibitor, IC50 7.0 μM, with antidepressant effects.Formule :C15H18ClNS2Degré de pureté :99.97%Couleur et forme :SolidMasse moléculaire :311.89NS13001
CAS :NS13001, an oral SK channel modulator, shows promise for SCA2 therapy; EC50: 1.8 µM (SK2), 0.14 µM (SK3).Formule :C17H16ClN7Degré de pureté :99.55%Couleur et forme :SolidMasse moléculaire :353.81Mefloquine hydrochloride
CAS :Mefloquine hydrochloride (Mefloquin hydrochloride) is a quinoline derivative used for the prevention and therapy of P. falciparum malaria.Formule :C17H17ClF6N2ODegré de pureté :99% - 99.99%Couleur et forme :Off-White To Yellow SolidMasse moléculaire :414.77Brompheniramine maleate
CAS :Brompheniramine maleate (Dimotane) is an antagonist against histamine H1 receptors.Formule :C16H19BrN2·C4H4O4Degré de pureté :99.80%Couleur et forme :Crystal PowderMasse moléculaire :435.31Dronedarone hydrochloride
CAS :Dronedarone hydrochloride (SR33589) is an amiodarone analog which has an effective and promising treatment for Atrial fibrillation.Formule :C31H44N2O5S·HClDegré de pureté :99.61%Couleur et forme :SolidMasse moléculaire :593.22Ref: TM-T1073
5mg35,00€10mg50,00€25mg82,00€50mg111,00€100mg166,00€200mg236,00€500mg403,00€1mL*10mM (DMSO)52,00€DCPIB
CAS :DCPIB, a known specific and potent inhibitor of volume-regulated anion channels (VRAC),DCPIB displayed superior selectivity toward TRESK with an IC50 of 0.14 μMFormule :C22H28Cl2O4Degré de pureté :99.79% - 99.87%Couleur et forme :SolidMasse moléculaire :427.36Ref: TM-T10979
2mg39,00€5mg57,00€10mg87,00€25mg177,00€50mg301,00€100mg485,00€200mg690,00€1mL*10mM (DMSO)63,00€Glibenclamide
CAS :Glibenclamide (Glyburide) is an antidiabetic sulfonylurea derivative with actions similar to those of chlorpropamide.Formule :C23H28ClN3O5SDegré de pureté :99.05% - 99.75%Couleur et forme :SolidMasse moléculaire :494.00VU0134992 hydrochloride
CAS :VU0134992 hydrochloride is the first subtype-preferring, orally active and selective blocker of Kir4.1 potassium channel pore(IC50 : 0.97 μM).Formule :C20H32BrClN2O2Degré de pureté :>99.99%Couleur et forme :SolidMasse moléculaire :447.84Ifenprodil Tartrate
CAS :Ifenprodil is a selective NMDA receptor (glutamate) antagonist.Formule :C21H27NO2C4H6O6Degré de pureté :99.02% - 99.55%Couleur et forme :SolidMasse moléculaire :400.49Amiodarone hydrochloride
CAS :Amiodarone HCl: Antianginal, class III antiarrhythmic. Lengthens heart muscle action, slows heart rate, reduces vascular resistance.Formule :C25H29I2NO3·HClDegré de pureté :99.82% - ≥95%Couleur et forme :White To Cream Crystalline PowderMasse moléculaire :681.78IK1 inhibitor PA-6
CAS :IK1 inhibitor PA-6 (PA-6) is a selective and potent inhibitor of IK1 (KIR2.x ion-channel-carried inward rectifier current)(IC50 of 12-15 nM for human and mouseFormule :C31H32N4O2Degré de pureté :98.9%Couleur et forme :SolidMasse moléculaire :492.61Clofilium tosylate
CAS :Clofilium tosylate is a potassium channel blocker, induces apoptosis on human promyelocytic leukemia (HL-60) cells.Formule :C28H44ClNO3SDegré de pureté :99.68% - >99.99%Couleur et forme :SolidMasse moléculaire :510.17Eleclazine hydrochloride
CAS :Eleclazine hydrochloride (GS 6615 hydrochloride) is a novel inhibitor of late Na+ current (IC50: 0.7 uM).Formule :C21H17ClF3N3O3Degré de pureté :99.86%Couleur et forme :SolidMasse moléculaire :451.83Ref: TM-T15207
1mg58,00€5mg110,00€10mg166,00€25mg268,00€50mg403,00€100mg532,00€200mg705,00€1mL*10mM (DMSO)122,00€Tannic acid
CAS :Tannic acid (Gallotannic acid) is a novel hERG channel blocker.Formule :C76H52O46Degré de pureté :AR - ARCouleur et forme :Light Yellow To Light Brown Solid Solid Particulate/PowderMasse moléculaire :1701.2Ketanserin
CAS :Ketanserin: quinazoline derivative, 5-HT2 receptor antagonist, may lower blood pressure and inhibit blood clots.Formule :C22H22FN3O3Degré de pureté :99.19% - 99.73%Couleur et forme :SolidMasse moléculaire :395.43Flindokalner
CAS :Flindokalner (BMS-204352) modulates potassium channels, enhances Kv7 subtypes and BKca, inhibits Kv7.1 (Ki=3.7μM), GABAA; has anxiolytic effects in vivo.Formule :C16H10ClF4NO2Degré de pureté :99.96%Couleur et forme :SolidMasse moléculaire :359.7ML418
CAS :ML418 is a potent, selective and CNS penetrating Kir7.1 potassium channel blocker (IC50 = 310 nM), and also potently inhibits Kir6.2/SUR1.Formule :C19H24ClN3O3Degré de pureté :99.3%Couleur et forme :SolidMasse moléculaire :377.87Ref: TM-T16110
1mg37,00€5mg79,00€10mg111,00€25mg178,00€50mg288,00€100mg414,00€200mg583,00€1mL*10mM (DMSO)84,00€Doxapram hydrochloride hydrate
CAS :Doxapram hydrochloride hydrate (Doxapram HCl) inhibits TASK-1, TASK-3, TASK-1/TASK-3 heterodimeric channel function with EC50 of 0.41, 37, 9 μM, respectively.Formule :C24H33ClN2O3C24H30N2O2·ClH·H2ODegré de pureté :99.64% - >99.99%Couleur et forme :SolidMasse moléculaire :432.99Apamin
CAS :Apamin: 18-amino acid bee venom peptide, blocks SK channels, anti-inflammatory, anti-fibrotic, strongly basic.Formule :C79H131N31O24S4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :2027.34Margatoxin
CAS :KV1.3 channel blocker, IC50 36 pM, no effect on calcium-activated channels, hinders VEGF-induced Ca++ influx & NO in endothelial cells.Formule :C178H286N52O50S7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :4178.96Charybdotoxin
CAS :Specific inhibitor of the big conductance Ca2+-activated K+ channel.Formule :C176H277N57O55S7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :4295.95Aam-KTX
Aam-KTX, a toxic peptide sourced from Mesobuthus eupeus scorpion venom, acts as a selective K_v channel inhibitor, exhibiting IC_50 values of 1.1 nM for K_v1.3Formule :C174H288N58O48S7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :4184.96Tamapin TFA
Tamapin TFA, a venom peptide isolated from the Indian red scorpion (Mesobuthus tamulus) [1], selectively targets and blocks small conductance Ca(2+)-activated KFormule :C146H238N44O41S6·xC2HF3O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :3458.11 (free base)AmmTX3 TFA
AmmTX3 TFA, a peptide toxin derived from Androctonus mauretanicus scorpion venom, functions as a selective blocker of the K_v4 channel.Formule :C158H262N50O48S6·xC2HF3O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :3822.47 (free acid)Hongotoxin-1
Hongotoxin-1, a chemical compound isolated from the venom of Centruroides limbatus, functions as a potassium channel inhibitor.Formule :C181H299N53O49S7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :4226.13Vm24-toxin
CAS :Vm24-toxin, a peptide toxin isolated from the Mexican scorpion Vaejovis mexicanus smithi, serves as an inhibitor of the Kv1.3 potassium channel [1].Formule :C157H253N51O45S9Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :3863.59Stromatoxin 1
CAS :Stromatoxin 1, a peptide isolated from tarantulas, acts as an inhibitor of various potassium channels, including K(V)2.1, K(V)2.2, K(V)4.2, and K(V)2.1/9.3.Formule :C156H237N49O48S7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :3791.31HsTX1
CAS :HsTX1, a 34-residue, C-terminally amidated peptide isolated from the scorpion Heterometrus spinnifer, features four disulfide bridges and acts as a potassiumFormule :C149H246N54O46S9Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :3818.47Tamapin
Tamapin, a venom peptide isolated from the Indian red scorpion (Mesobuthus tamulus) [1], selectively targets and blocks small-conductance Ca(2+)-activated KFormule :C146H238N44O41S6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :3458.11Iberiotoxin TFA
Iberiotoxin (TFA) is a selective inhibitor of high conductance Ca2+-activated K+ channels, exhibiting a dissociation constant (Kd) of approximately 1 nM, yet itFormule :C179H274N50O55S7·xC2HF3O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :4230.85 (free base)Spinoxin
CAS :Spinoxin, a 34-residue peptide neurotoxin extracted from the venom of Heterometrus spinifer, is characterized by four disulfide bridges.Formule :C147H236N48O46S9Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :3700.33Jingzhaotoxin-X
Jingzhaotoxin-X (JZTX-X) selectively inhibits Kv4.2 and Kv4.3 potassium channels, resulting in prolonged mechanical hyperalgesia [1].Formule :C164H242N46O41S6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :3706.35Ssm spooky toxin
Ssm Spooky Toxin, derived from Scolopendra mutilans, exhibits potent lethality affecting both hematological and respiratory systems primarily through theFormule :C270H413N69O79S4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :6017.84ShK toxin
CAS :ShK toxin, isolated from the Caribbean sea anemone (Stichodactyla helianthus), is an inhibitor of the voltage-dependent potassium channel (Kv1.3 channel).Formule :C169H274N54O48S7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :4054.8Dendrotoxin K
CAS :Dendrotoxin K blocks Kv1.1 channels, modulating glutamate release in CA3 neurons by controlling presynaptic spike timing.Formule :C294H462N84O75S6Couleur et forme :SolidMasse moléculaire :6559.66δ-Dendrotoxin
CAS :δ-Dendrotoxin is a potassium (K+) channel blocker derived from black mamba snake venom and is utilized in neurological disease research [1].Formule :C296H452N82O76S6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :6567.65Iberiotoxin
CAS :Selective blocker of the big conductance Ca2+-activated K+ channel.Formule :C179H274N50O55S7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :4230ADWX 1
Potent KV1.3 blocker, IC50: 0.0019 nM; less effective on KV1.1. Curbs CD4+ T cell activation; eases rat multiple sclerosis model.Formule :C169H281N57O46S7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :4071.86BmP02
BmP02, a compound isolated from Chinese scorpion (Buthus martensi Karsch) venom, acts as a selective Kv1.3 channel blocker and a highly-selective Kv4.2Formule :C115H182N36O41S7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :2949.35Noxiustoxin
CAS :Noxiustoxin, a toxin extracted from the venom of the Mexican scorpion Centruroides noxius, inhibits both the voltage-dependent potassium channel (Kv1.3, IC50 =Formule :C174H286N52O54S7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :4195Pandinotoxin Kα
CAS :Pandinotoxin Kα, a chemical compound extracted from the emperor scorpion (Pandinus imperator) venom, functions as an inhibitor of the A-type potassium channel [Formule :C169H267N53O48S7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :4033.71Tertiapin-RQ
Tertiapin-RQ, an inward rectifier potassium (K+) channel-blocking peptide, exhibits antidepressant effects [1].Formule :C106H175N37O25S4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :2496.02Tertiapin LQ
Kir1.1 channel blocker, 250x selective; Kd: Kir1.1 (1.1 nM), Kir3.1/3.2 (274 nM), Kir3.1/3.4 (361 nM). Tertiapin-Q derivative.Formule :C106H179N33O24S4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :2428.03Jingzhaotoxin-XII TFA
Jingzhaotoxin-XII (JzTx-XII) TFA is a specific inhibitor of the Kv4.1 channel, exhibiting an IC50 of 0.363 μM. It interacts with the channel by altering gating behavior.Couleur et forme :Odour SolidBDS-I
CAS :BDS-I, a marine toxin derived from Anemonia sulcata, functions as a selective inhibitor of the potassium channel, specifically targeting Kv3.4.Formule :C210H297N57O56S6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :4708.346-FAM-AEEAC-SHK TFA
6-FAM-AEEAC-SHK TFA, a peptide neurotoxin derived from Stichodactyla helianthus and conjugated with a fluorescent marker, selectively blocks voltage-gated potassium channels (kv1.1 and kv1.2). By prolonging action potentials, it interferes with neural signal conduction, making it valuable in neuroscience research.Formule :C196H295N55O57S7·xCHF3O2Couleur et forme :SolidMasse moléculaire :4558.23 (free acid)Aekatperone
Aekatperone, a reversible KATP channel inhibitor, exhibits an IC50 of 9 μM. It is utilized in research related to congenital hyperinsulinism (CHI).Formule :C20H25N5O2SCouleur et forme :SolidMasse moléculaire :399.51Hemitoxin
Hemitoxin, a scorpion-venom peptide, functions as a K+ channel blocker and selectively inhibits rat Kv1.1, Kv1.2, and Kv1.3 channels expressed in XenopusFormule :C159H259N49O49S8Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :3897.58GsAF-I
GsAF-I is a potent blocker of Na_v and hERG1 channels, exhibiting half-maximal inhibitory concentrations (IC50s) of 0.36 μM (Na_v 1.1), 0.6 μM (Na_v 1.2), 1.28Formule :C160H244N46O42S7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :3708.39Heteropodatoxin-2
CAS :Heteropodatoxin-2, a 30-amino acid peptide, inhibits the Kv4.2 current in Xenopus laevis oocytes through a voltage-dependent mechanism, exhibiting reducedFormule :C144H207N39O46S6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :3412.81Tertiapin-Q acetate
Tertiapin-Q acetate is a bee toxin derivative that inhibits BK-type K(+) channels in a concentration-dependent manner.Formule :C108H179N35O26S4Degré de pureté :96.44%Couleur et forme :SolidMasse moléculaire :2512.06Phe-Met-Arg-Phe amide trifluoroacetate
CAS :Phe-met-arg-phe amide trifluoroacetate is an activator of K+ current with an ED50 of 23nm on the fundus nerve.Formule :C33H44F6N8O8SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :826.81
