Canal potassique
Les canaux potassiques sont un groupe diversifié de protéines membranaires qui facilitent le flux des ions potassium (K+) à travers la membrane cellulaire. Ces canaux jouent un rôle crucial dans le maintien du potentiel de membrane au repos, la régulation du volume cellulaire et le contrôle de l'excitabilité des neurones et des cellules musculaires. Les canaux potassiques sont impliqués dans divers processus physiologiques, y compris la régulation du rythme cardiaque, la sécrétion d'insuline et la libération de neurotransmetteurs. La dysrégulation des canaux potassiques est liée à des conditions telles que les arythmies, l'épilepsie et l'hypertension. Chez CymitQuimica, nous proposons une large gamme de modulateurs de canaux potassiques pour soutenir vos recherches en électrophysiologie, santé cardiovasculaire et neurobiologie.
304 produits trouvés pour "Canal potassique"
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Tertiapin-RQ
Tertiapin-RQ, an inward rectifier potassium (K+) channel-blocking peptide, exhibits antidepressant effects [1].Formule :C106H175N37O25S4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :2496.02Jingzhaotoxin-XII TFA
Jingzhaotoxin-XII (JzTx-XII) TFA is a specific inhibitor of the Kv4.1 channel, exhibiting an IC50 of 0.363 μM. It interacts with the channel by altering gating behavior.Couleur et forme :Odour Solid6-FAM-AEEAC-SHK TFA
6-FAM-AEEAC-SHK TFA, a peptide neurotoxin derived from Stichodactyla helianthus and conjugated with a fluorescent marker, selectively blocks voltage-gated potassium channels (kv1.1 and kv1.2). By prolonging action potentials, it interferes with neural signal conduction, making it valuable in neuroscience research.Formule :C196H295N55O57S7·xCHF3O2Couleur et forme :SolidMasse moléculaire :4558.23 (free acid)Apamin acetate
Apamin acetate: Selective Ca2+-activated K+ channel blocker, 18-amino acid bee venom peptide, promotes synapse repair, anti-inflammatory.Degré de pureté :96.97%Couleur et forme :SolidTertiapin-Q acetate
Tertiapin-Q acetate is a bee toxin derivative that inhibits BK-type K(+) channels in a concentration-dependent manner.Formule :C108H179N35O26S4Degré de pureté :96.44%Couleur et forme :SolidMasse moléculaire :2512.06BmP02
BmP02, a compound isolated from Chinese scorpion (Buthus martensi Karsch) venom, acts as a selective Kv1.3 channel blocker and a highly-selective Kv4.2Formule :C115H182N36O41S7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :2949.35δ-Dendrotoxin
CAS :δ-Dendrotoxin is a potassium (K+) channel blocker derived from black mamba snake venom and is utilized in neurological disease research [1].Formule :C296H452N82O76S6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :6567.65Noxiustoxin
CAS :Noxiustoxin, a toxin extracted from the venom of the Mexican scorpion Centruroides noxius, inhibits both the voltage-dependent potassium channel (Kv1.3, IC50 =Formule :C174H286N52O54S7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :4195Ssm spooky toxin
Ssm Spooky Toxin, derived from Scolopendra mutilans, exhibits potent lethality affecting both hematological and respiratory systems primarily through theFormule :C270H413N69O79S4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :6017.84Spinoxin
CAS :Spinoxin, a 34-residue peptide neurotoxin extracted from the venom of Heterometrus spinifer, is characterized by four disulfide bridges.Formule :C147H236N48O46S9Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :3700.33Jingzhaotoxin-X
Jingzhaotoxin-X (JZTX-X) selectively inhibits Kv4.2 and Kv4.3 potassium channels, resulting in prolonged mechanical hyperalgesia [1].Formule :C164H242N46O41S6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :3706.35ShK toxin
CAS :ShK toxin, isolated from the Caribbean sea anemone (Stichodactyla helianthus), is an inhibitor of the voltage-dependent potassium channel (Kv1.3 channel).Formule :C169H274N54O48S7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :4054.8Stromatoxin 1
CAS :Stromatoxin 1, a peptide isolated from tarantulas, acts as an inhibitor of various potassium channels, including K(V)2.1, K(V)2.2, K(V)4.2, and K(V)2.1/9.3.Formule :C156H237N49O48S7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :3791.31HsTX1
CAS :HsTX1, a 34-residue, C-terminally amidated peptide isolated from the scorpion Heterometrus spinnifer, features four disulfide bridges and acts as a potassiumFormule :C149H246N54O46S9Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :3818.47Hongotoxin-1
Hongotoxin-1, a chemical compound isolated from the venom of Centruroides limbatus, functions as a potassium channel inhibitor.Formule :C181H299N53O49S7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :4226.13AmmTX3 TFA
AmmTX3 TFA, a peptide toxin derived from Androctonus mauretanicus scorpion venom, functions as a selective blocker of the K_v4 channel.Formule :C158H262N50O48S6·xC2HF3O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :3822.47 (free acid)Vm24-toxin
CAS :Vm24-toxin, a peptide toxin isolated from the Mexican scorpion Vaejovis mexicanus smithi, serves as an inhibitor of the Kv1.3 potassium channel [1].Formule :C157H253N51O45S9Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :3863.59Tamapin
Tamapin, a venom peptide isolated from the Indian red scorpion (Mesobuthus tamulus) [1], selectively targets and blocks small-conductance Ca(2+)-activated KFormule :C146H238N44O41S6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :3458.11Aam-KTX
Aam-KTX, a toxic peptide sourced from Mesobuthus eupeus scorpion venom, acts as a selective K_v channel inhibitor, exhibiting IC_50 values of 1.1 nM for K_v1.3Formule :C174H288N58O48S7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :4184.96Tamapin TFA
Tamapin TFA, a venom peptide isolated from the Indian red scorpion (Mesobuthus tamulus) [1], selectively targets and blocks small conductance Ca(2+)-activated KFormule :C146H238N44O41S6·xC2HF3O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :3458.11 (free base)Iberiotoxin TFA
Iberiotoxin (TFA) is a selective inhibitor of high conductance Ca2+-activated K+ channels, exhibiting a dissociation constant (Kd) of approximately 1 nM, yet itFormule :C179H274N50O55S7·xC2HF3O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :4230.85 (free base)Pandinotoxin Kα
CAS :Pandinotoxin Kα, a chemical compound extracted from the emperor scorpion (Pandinus imperator) venom, functions as an inhibitor of the A-type potassium channel [Formule :C169H267N53O48S7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :4033.71KTX-Sp2
KTX-Sp2, a potassium channel toxin, effectively blocks exogenous voltage-gated potassium channels Kv1.1, Kv1.2, and Kv1.3, as well inhibits the endogenous Kv1.3Formule :C155H244N58O49S7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :3928.41Dendrotoxin-I
CAS :Dendrotoxin-I, a neurotoxin from Dendroaspis snake venom, potently blocks K⁺ channels, specifically targeting voltage-gated potassium channel subunits KV1.1 andFormule :C312H491N99O83S6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :7149.24Maurotoxin
CAS :Maurotoxin, a 34-residue peptide featuring four disulfide bridges, is extracted from the chactoid scorpion (Scorpio maurus) and known to impede Shaker potassiumFormule :C145H232N46O46S8Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :3612.19κM-Conotoxin RIIIJ
κM-Conotoxin RIIIJ (κM-RIIIJ) selectively inhibits Kv1.2 channels, exhibiting an IC50 value of 33 nM [1].Formule :C117H184N32O36S6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :2807.3Slotoxin
Slotoxin, a peptide extracted from the venom of the Centruroides noxius Hoffmann scorpion, inhibits high-conductance calcium-activated potassium channels with aFormule :C177H275N47O50S7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :4085.82Phrixotoxin 2
CAS :Phrixotoxin 2 selectively blocks the KV 4.2 and KV 4.3 channels, demonstrating high specificity in its interaction with these voltage-gated ion channels [1].Formule :C169H259N49O43S8Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :3921.69Aa1 toxin
Aa1 toxin, sourced from Androctonus australis Garzoni venom, is a neurotoxic peptide that specifically blocks potassium channels and has applications inFormule :C156H260N54O49S6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :3868.46Potassium Channel Targeted Library
A unique collection of xnum potassium channel blockers and agonists for high throughput and high content screening;Couleur et forme :Odour SolidRef: TM-L7300
1mgÀ demander30μL*10mM (DMSO)À demander50μL*10mM (DMSO)À demander100μL*10mM (DMSO)À demander250μL*10mM (DMSO)À demanderIon Channel Targeted Library
A unique collection of 931 compounds targeting ion channels for research in ion channels-related diseases and ion channel drug discovery;
Couleur et forme :Odour SolidADWX 1 TFA
ADWX 1 TFA is a novel peptide that potently targets and inhibits the Kv1.3 channel, with an IC50 of 1.89 pM. It specifically suppresses the activity of the Kv1.3 channel, in addition to inhibiting initial calcium signaling and NF-κB activation. This compound has been shown to ameliorate symptoms in rats with experimental autoimmune encephalomyelitis (EAE). ADWX 1 TFA is utilized in research focused on T-cell-mediated autoimmune diseases.Formule :C169H281N57O46S7·xC2HF3O2Couleur et forme :SolidMasse moléculaire :4071.85 (free base)Cesium chloride
CAS :Cesium chloride (CsCl) is considered to be the most toxic of the alkali chlorides, inhibiting fungal growth.Formule :ClCsDegré de pureté :98%Couleur et forme :White Solid CrystallineMasse moléculaire :168.36Myomodulin
CAS :Myomodulin is a neuropeptide present in molluscs, insects, and gastropods.Myomodulin is present in two identified aplysia neurons that contain myomodulin A theFormule :C36H67N11O8S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :846.12Mesoridazine Besylate
CAS :Mesoridazine Besylate (Serentil), a piperidine antipsychotic and phenothiazine, treats schizophrenia; it's a thioridazine metabolite.Formule :C27H32N2O4S3Degré de pureté :98.87%Couleur et forme :SolidMasse moléculaire :544.75KNa1.1-IN-2
CAS :KNa1.1-IN-2 (Compound Z05) is a selective KNa1.1 channel inhibitor capable of penetrating the blood-brain barrier, and exhibits significant efficacy on hERG channels. It binds to KNa1.1 channels, effectively blocking channel activity caused by Gain-of-function (GOF) mutations, thus intervening in KCNT1-related seizures. Additionally, it inhibits the GOF mutant Y796H, making KNa1.1-IN-2 a promising candidate for research into KCNT1-associated epilepsy disorders.Formule :C24H27NOCouleur et forme :SolidMasse moléculaire :345.48KV1.3-IN-1
KV1.3-IN-1 (Compound trans-18), a selective KV1.3 channel inhibitor with IC50 values of 230 nM in Ltk cells and 26.12 nM in PHA-activated T-lymphocytes,Formule :C23H30N2O4SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :430.56Dendrotoxin K TFA
Dendrotoxin K TFA, a Kv1.1 channel blocker, modulates glutamate release in CA3 neurons by time-dependently regulating the presynaptic spike waveform [1].Formule :C294H462N84O75S6·XC2HF3OC2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :6559.66 (free base)Flecainide
CAS :Flecainide is an orally administered antiarrhythmic agent acting as a sodium channel blocker and IKr inhibitor,PSVT.Formule :C17H20F6N2O3Degré de pureté :99.896%Couleur et forme :SolidMasse moléculaire :414.34Ref: TM-T21391
5mg46,00€10mg66,00€25mg111,00€50mg177,00€100mg268,00€200mg335,00€1mL*10mM (DMSO)49,00€Nateglinide D5
CAS :Nateglinide D5 is a deuterium labeled Nateglinide.Formule :C19H27NO3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :322.45Cromakalim
CAS :Cromakalim (BRL 34915) is an ATP-dependent K(+) channel opener, a smooth muscle relaxant with antiepileptic activity.Formule :C16H18N2O3Degré de pureté :99.39%Couleur et forme :SolidMasse moléculaire :286.33KCNQ1 activator-1
CAS :N-[4-(4-Methoxyphenyl)-2-thiazolyl]-2-piperidinecarboxamide is a potent KCNQ1 activator for LQTS research.Formule :C22H23N3O4S2Degré de pureté :99.71%Couleur et forme :SolidMasse moléculaire :457.57Ref: TM-T9778
1mg40,00€5mg89,00€10mg130,00€25mg219,00€50mg324,00€100mg462,00€200mg655,00€1mL*10mM (DMSO)96,00€Clamikalant sodium
CAS :Clamikalant sodium (HMR 1098) is an ATP-dependent potassium channel (KATP) cardiac-selective blocker, used in the study of arrhythmias.Formule :C19H21ClN3NaO5S2Degré de pureté :99.95%Couleur et forme :SolidMasse moléculaire :493.96Ref: TM-T63330
1mg48,00€5mg90,00€10mg172,00€25mg346,00€50mg546,00€100mg855,00€200mg1.170,00€1mL*10mM (DMSO)99,00€Endoxifen Z-isomer hydrochloride
CAS :Endoxifen Z-isomer hydrochloride (Endoxifen HCl) is the active metabolite of Tamoxifen, which is an effective and selective estrogen receptor antagonist.Formule :C25H28ClNO2Couleur et forme :SolidMasse moléculaire :409.95Neosolaniol
CAS :Neosolaniol, a type A trichothecene mycotoxin produced by Fusarium species, strongly induces an anorectic (loss of appetite) response.Formule :C19H26O8Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :382.4QO-58
CAS :QO-58 is a novel Kv7 activator (opener) that activates neuronal Kv7/KCNQ/M channels, danti-nociceptive effects on inflammatory painFormule :C18H8Cl2F4N4ODegré de pureté :99.17%Couleur et forme :SolidMasse moléculaire :443.18Enflurane
CAS :Enflurane (Efrane), a volatile anaesthetic, inhibits Ca2+-activated K+ channels and is used to gauge anesthesia levels in gas chromatography.Formule :C3H2ClF5ODegré de pureté :99.64%Couleur et forme :Clear Colorless Liquid Ordinary Temperature And Pressure Bp 56 8°C Density 1 50 G Cm-3 At Room Temperature Used As AnMasse moléculaire :184.49Rimtuzalcap
CAS :Rimtuzalcap (CAD-1883), a selective modulator for SK channels, may treat movement disorders like SCA and ET.Formule :C18H24F2N6ODegré de pureté :99.64%Couleur et forme :SolidMasse moléculaire :378.42Ref: TM-T9522
1mg34,00€5mg73,00€10mg105,00€25mg205,00€50mg304,00€100mg429,00€200mg600,00€1mL*10mM (DMSO)33,00€SCH-23390 hydrochloride
CAS :SCH-23390 hydrochloride (R-(+)-SCH23390 hydrochloride) is an effective dopamine receptor antagonist, and for the D1(Ki=0.2 nM) and D5(Ki=0.3 nM).Formule :C17H19Cl2NODegré de pureté :98% - 99.83%Couleur et forme :SolidMasse moléculaire :324.24Ref: TM-T4369
1mg39,00€2mg50,00€5mg78,00€10mg97,00€25mg195,00€50mg369,00€100mg550,00€1mL*10mM (DMSO)78,00€20(S)-Ginsenoside Rg3
CAS :20(S)-Ginsenoside Rg3 (Rg3) possess an ability to inhibit the lung metastasis of tumor cells via inhibition of the adhesion and invasion of tumor cells.Formule :C42H72O13Degré de pureté :98.11% - 99.93%Couleur et forme :SolidMasse moléculaire :785.01Tetrandrine
CAS :Tetrandrine (Sinomenine A) is a naturally occurring biphenylisoquinoline alkaloid, a calcium channel inhibitor. Cost-effective and quality-assured.Formule :C38H42N2O6Degré de pureté :99.61% - 99.94%Couleur et forme :White SolidMasse moléculaire :622.75NS 11021
CAS :NS 11021 (NS11021) , a novel opener of large-conductance Ca(2+)-activated K(+) channelsFormule :C16H9BrF6N6SDegré de pureté :97.26%Couleur et forme :SolidMasse moléculaire :511.24Ref: TM-T4294
1mg42,00€5mg88,00€10mg128,00€25mg263,00€50mg447,00€100mg760,00€200mg1.018,00€1mL*10mM (DMSO)89,00€Tetraethylammonium bromide
CAS :Tetraethylammonium bromide (TEA bromide) can selectively block potassium channels.
Formule :C8H20BrNDegré de pureté :98%Couleur et forme :White SolidMasse moléculaire :210.16Tetraethylammonium chloride
CAS :Tetraethylammonium chloride is a quaternary ammonium compound.Formule :C8H20ClNDegré de pureté :≥95%Couleur et forme :White Solid Solid Particulate/PowderMasse moléculaire :165.7ML133 hydrochloride
CAS :ML133 hydrochloride (ML133 HCl) is a selective potassium channel inhibitor for Kir2.1, has no effect on Kir1.1 and weak activity for Kir4.1 and Kir7.1.Formule :C19H19NO·HClDegré de pureté :99.48%Couleur et forme :SolidMasse moléculaire :313.82Ref: TM-T6592
5mg48,00€10mg63,00€25mg101,00€50mg161,00€100mg259,00€200mg335,00€500mg567,00€1mL*10mM (DMSO)50,00€KCNQ2/3 activator-1
CAS :KCNQ2/3 activator-1 is a Kv7.2/Kv7.3 (KCNQ2/3) potassium channel activator.Formule :C23H29FN2ODegré de pureté :99.16% - 99.47%Couleur et forme :SolidMasse moléculaire :368.49Ref: TM-T9400
2mg38,00€5mg58,00€10mg89,00€25mg144,00€50mg224,00€100mg353,00€500mg888,00€1mL*10mM (DMSO)64,00€RY785
CAS :RY785 is a potent and selective inhibitor of voltage-gated potassium channel such as KV2.2 (IC50 = 50 nM). RY785 may be used in pain relief studies.Formule :C21H20N4O2SDegré de pureté :99.78%Couleur et forme :SolidMasse moléculaire :392.47Ref: TM-T12786
1mg49,00€5mg137,00€10mg222,00€25mg378,00€50mg530,00€100mg745,00€200mg1.035,00€1mL*10mM (DMSO)118,00€SKF-96365 hydrochloride
CAS :SKF-96365 hydrochloride (SKF96365) , a SOCE inhibitor, exhibits potent anti-neoplastic activity by inducing cell-cycle arrest and apoptosis in colorectal YFormule :C22H27ClN2O3Degré de pureté :99.47% - 99.92%Couleur et forme :SolidMasse moléculaire :402.91Ref: TM-T2170
5mg54,00€10mg81,00€25mg131,00€50mg230,00€100mg445,00€200mg680,00€500mg1.054,00€1mL*10mM (DMSO)59,00€CLP290
CAS :CLP290 is an activator of the neuron-specific K+-Cl cotransporter KCC2 and displays potential for the treatment of a wide range of neurological and psychiatricFormule :C19H21FN4O3SDegré de pureté :99.93% - >99.99%Couleur et forme :SolidMasse moléculaire :404.46Ref: TM-T5444
1mg34,00€5mg73,00€10mg116,00€25mg190,00€50mg286,00€100mg430,00€200mg628,00€1mL*10mM (DMSO)62,00€Oxypeucedanin
CAS :1.Formule :C16H14O5Degré de pureté :98.66% - 98.85%Couleur et forme :SolidMasse moléculaire :286.28Guanosine 5'-diphosphate
CAS :Guanosine 5'-diphosphate (GDP) as Potential Iron Mobilizer, Preventing the Hepcidin-Ferroportin Interaction and Modulating the Interleukin-6/Stat-3 Pathway.Formule :C10H15N5O11P2Degré de pureté :98.46% - 99.52%Couleur et forme :SolidMasse moléculaire :443.2VU0134992
CAS :VU0134992 is an Kir4.1 blocker with an IC50 value of 0.97 μMFormule :C20H31BrN2O2Degré de pureté :99.86%Couleur et forme :SolidMasse moléculaire :411.38XE 991 dihydrochloride
CAS :XE 991 dihydrochloride is a Kv7 (KCNQ) channel blocker.Formule :C26H22Cl2N2ODegré de pureté :98.68%Couleur et forme :SolidMasse moléculaire :449.37BMS-191011
CAS :BMS-191011 (BMS-A) is an activator of large-conductance calcium-activated potassium (BKCa) channels ,effective in stroke modelsFormule :C16H10ClF3N2O3Degré de pureté :97.43%Couleur et forme :SolidMasse moléculaire :370.71Guanosine 5'-diphosphate disodium salt
CAS :5'-GDP-Na2: a nucleoside diphosphate, iron mobilizer, blocks hepcidin-ferroportin, affects IL-6/stat-3.
Formule :C10H13N5Na2O11P2Degré de pureté :99.40%Couleur et forme :White PowderMasse moléculaire :487.16ML 297
CAS :ML 297 is a selective Kir3.1/3.2 (GIRK1/2) channel activator (IC50 values are 160, 887 and 914 nM for GIRK1/2, GIRK1/4 and GIRK1/3 respectively).Formule :C17H14F2N4ODegré de pureté :97.85%Couleur et forme :SolidMasse moléculaire :328.32NS1643
CAS :NS1643 is a potent human ether-a-go-go related gene (hERG) KV11.1 channel activator with EC50 of 10.5 μM.Formule :C15H10F6N2O3Degré de pureté :98.37% - 99.31%Couleur et forme :SolidMasse moléculaire :380.24GAL-021
CAS :GAL-021 an intravenous BKCa-channel blocker.Formule :C11H22N6ODegré de pureté :97.71% - 99.66%Couleur et forme :SolidMasse moléculaire :254.33Ref: TM-T3557
1mg34,00€5mg71,00€10mg98,00€25mg177,00€50mg268,00€100mg414,00€500mg888,00€1mL*10mM (DMSO)80,00€Daurisoline
CAS :Daurisoline ((R,R)-Daurisoline) is a hERG inhibitor. Daurisoline is also an autophagy blocker.Formule :C37H42N2O6Degré de pureté :98% - 99.96%Couleur et forme :Light Yellow PowderMasse moléculaire :610.74Talatisamine
CAS :Talatisamine and TEA mitigate Aβ oligomer effects on I(K), bolstering cell survival and reducing K(+) loss-induced apoptosis; promising for further study.Formule :C24H39NO5Degré de pureté :98.62% - 99.44%Couleur et forme :SolidMasse moléculaire :421.57NS-1619
CAS :NS1619 have cardio-protective effects after ischemia-reperfusion injury.Formule :C15H8F6N2O2Degré de pureté :97.66% - 98%Couleur et forme :SolidMasse moléculaire :362.23Quinidine
CAS :Quinidine is a stereoisomer of the antimalarial agent quinine and a class Ia antiarrhythmic agent. for the treatment of abnormal heart rhythms and also malaria.Formule :C20H24N2O2Degré de pureté :97.03% - 99.99%Couleur et forme :Crystals With 2 5 Mol Water Of Crystallization; Crystals From Dilute Alcohol Physical Description Crystals Or White Powder (Ntp 1992)Masse moléculaire :324.42Ibutilide Fumarate
CAS :Ibutilide Fumarate is a class III antiarrhythmic, prolonging action potentials by enhancing sodium influx, and can extend QT interval.Formule :(C20H36N2O3S)2·C4H4O4Degré de pureté :99.68% - 99.74%Couleur et forme :SolidMasse moléculaire :885.23GW9508
CAS :GW9508(GW 9508) is a potent and selective agonist for FFA1 (GPR40), stimulates insulin secretion in a glucose-sensitive manner.
Formule :C22H21NO3Degré de pureté :97.89% - 99.19%Couleur et forme :SolidMasse moléculaire :347.41JNJ 303
CAS :JNJ 303 is a potent blocker of IKs (IC50 : 64 nM).Formule :C21H29ClN2O4SDegré de pureté :99.28%Couleur et forme :SolidMasse moléculaire :440.98Ref: TM-T7653
1mg46,00€2mg62,00€5mg94,00€10mg140,00€25mg309,00€50mg447,00€100mg667,00€1mL*10mM (DMSO)96,00€TRAM-34
CAS :TRAM-34 (Triarylmethane-34), an effective and specific inhibitor of the intermediate-conductance Ca2+-activated K+ channel, does not block cytochrome P450.
Formule :C22H17ClN2Degré de pureté :99.01% - 99.91%Couleur et forme :SolidMasse moléculaire :344.84ML335
CAS :ML335 is a selective activator of TREK-1 and TREK-2.Formule :C15H14Cl2N2O3SDegré de pureté :99.73% - 99.79%Couleur et forme :SolidMasse moléculaire :373.25Ref: TM-T4224
2mg40,00€5mg59,00€10mg89,00€25mg177,00€50mg268,00€100mg401,00€200mg580,00€1mL*10mM (DMSO)59,00€BAPTA-AM
CAS :BAPTA-AM is a calcium chelator that is cell-permeable and selective, blocking hERG, hKv1.3, and hKv1.5 channels (IC50=1.3/1.45/1.23 μM).Formule :C34H40N2O18Degré de pureté :98% - 99.47%Couleur et forme :White Powder Or Crystalline PowderMasse moléculaire :764.68NS309
CAS :NS309 activates SK/KCa2, IK/KCa3.1 (0.12-1.2 μM EC50, 10-90 nM EC50), and Kv11.1 channels; doesn't affect BK/KCa1.1; modulates neuronal firing.Formule :C8H4Cl2N2O2Degré de pureté :97.55%Couleur et forme :SolidMasse moléculaire :231.04Ref: TM-T4612
5mg54,00€10mg65,00€25mg113,00€50mg205,00€100mg305,00€200mg445,00€500mg712,00€1mL*10mM (DMSO)59,00€ICA 110381
CAS :ICA 110381 is a KCNQ2/Q3 potassium channel opener for the treatment of epilepsyFormule :C12H8Cl2N2ODegré de pureté :97.72%Couleur et forme :SolidMasse moléculaire :267.11Flecainide hydrochloride
CAS :Flecainide is a medication used to prevent and treat abnormally fast heart rates. This includes ventricular and supraventricular tachycardias.Formule :C17H21ClF6N2O3Degré de pureté :97.79%Couleur et forme :SolidMasse moléculaire :450.81ICA-069673
CAS :ICA-069673 is an activator of KCNQ2/Q3 potassium channel (IC50: 0.69 μM).Formule :C11H6ClF2N3ODegré de pureté :99.04% - 99.68%Couleur et forme :SolidMasse moléculaire :269.63TKIM
CAS :TKIM is a TWIK-related potassium channel 1 (TREK-1) inhibitor, binding to the pocket of the intermediate (IM) state of TREK-1.Formule :C18H14ClN3O2SDegré de pureté :99.47%Couleur et forme :SolidMasse moléculaire :371.84Ref: TM-T8700
1mg39,00€5mg89,00€10mg124,00€25mg212,00€50mg298,00€100mg399,00€200mg537,00€1mL*10mM (DMSO)96,00€Amifampridine
CAS :Amifampridine blocks nerve potassium channels, extends action potentials, boosts acetylcholine release, and treats rare muscle diseases.Formule :C5H7N3Degré de pureté :99.82%Couleur et forme :Slightly Beige PowderMasse moléculaire :109.13APD668
CAS :APD668 is a potent GPR119 agonist with EC50 of 2.7 nM and 33 nM for hGPR119 and ratGPR119, respectively.Formule :C21H24FN5O5SDegré de pureté :99.74% - 99.97%Couleur et forme :SolidMasse moléculaire :477.51ML277
CAS :ML277 (CID-53347902) was identified as a potent activator of KCNQ1 channels (EC(50)=260 nM).Formule :C23H25N3O4S2Degré de pureté :99.35%Couleur et forme :SolidMasse moléculaire :471.59Quinidine sulfate dihydrate
CAS :Quinidine sulfate dihydrate (Pitayine Sodium) is a potent and selective cytochrome P450db inhibitorFormule :C40H54N4O10SDegré de pureté :99.85%Couleur et forme :White To Light Yellow Crystal PowdeMasse moléculaire :782.9Ref: TM-T8125
5mg42,00€10mg52,00€25mg73,00€50mg94,00€100mg142,00€200mg207,00€500mg348,00€1mL*10mM (DMSO)62,00€Cholesterol myristate
CAS :Cholesterol myristate, a natural steroid in Chinese medicine, affects GABAA, nicotinic receptors, and potassium channels.
Formule :C41H72O2Degré de pureté :99.65%Couleur et forme :SolidMasse moléculaire :597.01Dofetilide
CAS :Dofetilide (UK 68789), a class III antiarrhythmic sulfonamide, blocks Ikr cardiac channels, prolongs action potential, and treats atrial fibrillation/flutter.Formule :C19H27N3O5S2Degré de pureté :97.85% - 99.06%Couleur et forme :Off-White Or Yellowish Crystalline PowderMasse moléculaire :441.56Ref: TM-T6476
2mg34,00€5mg50,00€10mg65,00€25mg108,00€50mg167,00€100mg234,00€200mg348,00€1mL*10mM (DMSO)52,00€Minoxidil sulfate
CAS :Minoxidil sulfate (U-58838) is the active metabolite required to exert the vasodilatory and hair growing effects of minoxidil.Formule :C9H15N5O4SDegré de pureté :99.01% - 99.72%Couleur et forme :White Crystalline SolidMasse moléculaire :289.31ASP2905
CAS :ASP-2905 is a potent and selective inhibitor of potassium channel Kv12.2 encoded by the Kcnh3/BEC1 gene.Formule :C20H17FN8Degré de pureté :97.29% - 99.78%Couleur et forme :SolidMasse moléculaire :388.4Ref: TM-T9070
1mg34,00€2mg46,00€5mg66,00€10mg90,00€25mg178,00€50mg295,00€100mg485,00€1mL*10mM (DMSO)73,00€AM-92016 hydrochloride
CAS :AM-92016 is a specific blocker of rectifier potassium current.Formule :C19H24Cl2N2O4S·HClDegré de pureté :98.68%Couleur et forme :SolidMasse moléculaire :483.84Ref: TM-T5585
2mg34,00€5mg50,00€10mg92,00€25mg156,00€50mg264,00€100mg378,00€200mg537,00€1mL*10mM (DMSO)55,00€AUT1
CAS :AUT1 (AUT-1) is a novel specific modulator of Kv3 channels (EC50: 4.7 and 4.9 uM for Kv3.1b and Kv3.2a).Formule :C18H19N3O4Degré de pureté :99.8% - 99.95%Couleur et forme :SolidMasse moléculaire :341.36Ref: TM-T5183
1mg34,00€2mg47,00€5mg71,00€10mg101,00€25mg177,00€50mg264,00€100mg404,00€200mg583,00€1mL*10mM (DMSO)79,00€Iptakalim Hydrochloride
CAS :Iptakalim, a lipophilic para-amino compound, is a novel ATP-sensitive potassium channel (KATP) opener, as well as an α4β2-containing nicotinic acetylcholineFormule :C9H22ClNDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :179.731GSK369796 Dihydrochloride
CAS :GSK369796 Dihydrochloride (N-tert-butylisoquine),is an anti-malaria drug candidate.Formule :C20H24Cl3N3ODegré de pureté :>99.99%Couleur et forme :SolidMasse moléculaire :428.78Ref: TM-T7195
1mg74,00€2mg96,00€5mg141,00€10mg185,00€25mg353,00€50mg532,00€100mg760,00€1mL*10mM (DMSO)138,00€Sematilide hydrochloride
CAS :Sematilide hydrochloride (CK-1752) is a class III antiarrhythmic. It is a selectively delayed rectifier K+ current (IKr) channel blocker.Formule :C14H24ClN3O3SDegré de pureté :99.14%Couleur et forme :SolidMasse moléculaire :349.87Ropivacaine hydrochloride monohydrate
CAS :Ropivacaine hydrochloride monohydrate (LEA-103 HCl) is an anaesthetic agent and blocks impulse conduction through inhibiting sodium ion influx reversibly.Formule :C17H29ClN2O2Degré de pureté :99.94% - 99.95%Couleur et forme :White SolidMasse moléculaire :328.882,2,2-Trichloroethanol
CAS :2,2,2-Trichloroethanol is an agonist of the nonclassical K2P channels TREK-1 and TRAAK.Formule :C2H3Cl3ODegré de pureté :99.74%Couleur et forme :LiquidMasse moléculaire :149.4PAP-1
CAS :PAP-1 (5-(4-Phenoxybutoxy)psoralen) is a selective, and orally active Kv1.3 blocker (EC50: 2 nM).Formule :C21H18O5Degré de pureté :99.35% - 99.75%Couleur et forme :White SolidMasse moléculaire :350.36Ref: TM-TQ0179
2mg63,00€5mg88,00€10mg136,00€25mg291,00€50mg520,00€100mg550,00€200mg785,00€1mL*10mM (DMSO)90,00€Quinine dihydrochloride
CAS :Quinine dihydrochloride (Quinine bimuriate) is a primary alkaloid of various species of Cinchona (Rubiaceae).Formule :C20H26Cl2N2O2Degré de pureté :99.79% - 99.97%Couleur et forme :White SolidMasse moléculaire :397.34
