Canal potassique
Les canaux potassiques sont un groupe diversifié de protéines membranaires qui facilitent le flux des ions potassium (K+) à travers la membrane cellulaire. Ces canaux jouent un rôle crucial dans le maintien du potentiel de membrane au repos, la régulation du volume cellulaire et le contrôle de l'excitabilité des neurones et des cellules musculaires. Les canaux potassiques sont impliqués dans divers processus physiologiques, y compris la régulation du rythme cardiaque, la sécrétion d'insuline et la libération de neurotransmetteurs. La dysrégulation des canaux potassiques est liée à des conditions telles que les arythmies, l'épilepsie et l'hypertension. Chez CymitQuimica, nous proposons une large gamme de modulateurs de canaux potassiques pour soutenir vos recherches en électrophysiologie, santé cardiovasculaire et neurobiologie.
304 produits trouvés pour "Canal potassique"
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AmmTX3
KV4 channel blocker that inhibits A-type K+ current in mouse neurons; requires DPP6 and DPP10 for effect.Formule :C158H262N50O48S6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :3822.47δ-Dendrotoxin
CAS :δ-Dendrotoxin is a potassium (K+) channel blocker derived from black mamba snake venom and is utilized in neurological disease research [1].Formule :C296H452N82O76S6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :6567.65Noxiustoxin
CAS :Noxiustoxin, a toxin extracted from the venom of the Mexican scorpion Centruroides noxius, inhibits both the voltage-dependent potassium channel (Kv1.3, IC50 =Formule :C174H286N52O54S7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :4195BKCa activator-1
BKCa activator-1 (Compound 51b) is an orally active activator of BKCa calcium-activated potassium channels with an EC50 of 2.82 μM. It promotes K+ efflux, leading to cell membrane hyperpolarization and inhibition of smooth muscle contraction. In a spontaneous hypertensive rat (SHR) model, it alleviates urinary incontinence and exhibits antitussive effects in a guinea pig cough model.Formule :C22H23F7N2O3Couleur et forme :SolidMasse moléculaire :496.418Lei-Dab7 TFA
Lei-Dab7 TFA blocks SK2 channels with 3.8 nM affinity, is >200x selective, and enhances LTP in rat hippocampus.Formule :C143H237F3N46O41S6Couleur et forme :SolidMasse moléculaire :3506.08Apamin
CAS :Apamin: 18-amino acid bee venom peptide, blocks SK channels, anti-inflammatory, anti-fibrotic, strongly basic.Formule :C79H131N31O24S4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :2027.34Ssm spooky toxin
Ssm Spooky Toxin, derived from Scolopendra mutilans, exhibits potent lethality affecting both hematological and respiratory systems primarily through theFormule :C270H413N69O79S4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :6017.84Agitoxin-2
CAS :Potent Shaker K+ channel blocker (Ki = 0.64 nM). Also inhibits Kv1.3, Kv1.6 and Kv1.1 K+ channels (Ki values are 4, 37 and 44 pM respectively).Formule :C169H278N54O48S8Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :4090.87HG1 Toxin
HG1 Toxin is a peptide found in the venom of the scorpion Heterometrus fulvipes, known for its ability to inhibit the potassium channel Kv1.3 (potassium channel Kv1.3). Additionally, HG1 Toxin exhibits trypsin inhibitory activity (Ki=107 nM), making it useful for research into autoimmune diseases.Formule :C337H503N103O97S6Masse moléculaire :7736.59176RU-TRAAK-2
CAS :RU-TRAAK-2 reversibly inhibits TWIK-related K+ channel, inactive on Kv1.2, GIRK2, Slo1.
Formule :C19H17N3OSDegré de pureté :99.81%Couleur et forme :SolidMasse moléculaire :335.42Tertiapin-RQ
Tertiapin-RQ, an inward rectifier potassium (K+) channel-blocking peptide, exhibits antidepressant effects [1].Formule :C106H175N37O25S4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :2496.02Apamin acetate
Apamin acetate: Selective Ca2+-activated K+ channel blocker, 18-amino acid bee venom peptide, promotes synapse repair, anti-inflammatory.Degré de pureté :96.97%Couleur et forme :SolidTertiapin
CAS :Tertiapin (reduced) is a synthetic bee venom peptide characterized by disulfide bonds between Cys3-Cys14 and Cys5-Cys18. It acts as an inhibitor of inward-rectifying potassium channels (potassium Channel) and can also block the activity of calcium-activated large conductance potassium channels. Tertiapin (reduced) is utilized in research related to diseases such as rheumatoid arthritis and multiple sclerosis.Formule :C106H180N34O23S5Couleur et forme :SolidMasse moléculaire :2459.1Tertiapin-Q acetate
Tertiapin-Q acetate is a bee toxin derivative that inhibits BK-type K(+) channels in a concentration-dependent manner.Formule :C108H179N35O26S4Degré de pureté :96.44%Couleur et forme :SolidMasse moléculaire :2512.06BmP02
BmP02, a compound isolated from Chinese scorpion (Buthus martensi Karsch) venom, acts as a selective Kv1.3 channel blocker and a highly-selective Kv4.2Formule :C115H182N36O41S7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :2949.35Spinoxin
CAS :Spinoxin, a 34-residue peptide neurotoxin extracted from the venom of Heterometrus spinifer, is characterized by four disulfide bridges.Formule :C147H236N48O46S9Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :3700.33Tamapin
Tamapin, a venom peptide isolated from the Indian red scorpion (Mesobuthus tamulus) [1], selectively targets and blocks small-conductance Ca(2+)-activated KFormule :C146H238N44O41S6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :3458.11KV1.3-IN-1
KV1.3-IN-1 (Compound trans-18), a selective KV1.3 channel inhibitor with IC50 values of 230 nM in Ltk cells and 26.12 nM in PHA-activated T-lymphocytes,Formule :C23H30N2O4SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :430.56QO-58
CAS :QO-58 is a novel Kv7 activator (opener) that activates neuronal Kv7/KCNQ/M channels, danti-nociceptive effects on inflammatory painFormule :C18H8Cl2F4N4ODegré de pureté :99.17%Couleur et forme :SolidMasse moléculaire :443.18Clamikalant sodium
CAS :Clamikalant sodium (HMR 1098) is an ATP-dependent potassium channel (KATP) cardiac-selective blocker, used in the study of arrhythmias.Formule :C19H21ClN3NaO5S2Degré de pureté :99.95%Couleur et forme :SolidMasse moléculaire :493.96Ref: TM-T63330
1mg48,00€5mg90,00€10mg172,00€25mg346,00€50mg546,00€100mg855,00€200mg1.170,00€1mL*10mM (DMSO)99,00€
