Canal potassique
Les canaux potassiques sont un groupe diversifié de protéines membranaires qui facilitent le flux des ions potassium (K+) à travers la membrane cellulaire. Ces canaux jouent un rôle crucial dans le maintien du potentiel de membrane au repos, la régulation du volume cellulaire et le contrôle de l'excitabilité des neurones et des cellules musculaires. Les canaux potassiques sont impliqués dans divers processus physiologiques, y compris la régulation du rythme cardiaque, la sécrétion d'insuline et la libération de neurotransmetteurs. La dysrégulation des canaux potassiques est liée à des conditions telles que les arythmies, l'épilepsie et l'hypertension. Chez CymitQuimica, nous proposons une large gamme de modulateurs de canaux potassiques pour soutenir vos recherches en électrophysiologie, santé cardiovasculaire et neurobiologie.
276 produits trouvés pour "Canal potassique"
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Nicorandil
CAS :<p>Nicorandil (SG-75)(Ikorel) acts by relaxing the smooth muscle of the blood vessels, especially those of the venous system.</p>Formule :C8H9N3O4Degré de pureté :98.14% - >99.99%Couleur et forme :White Or Off-White PowderMasse moléculaire :211.17Oxybutynin chloride
CAS :<p>Oxybutynin chloride (Oxybutynin HCl) is an anticholinergic medication used to relieve urinary and bladder difficulties.</p>Formule :C22H32ClNO3Degré de pureté :99.27% - >99.99%Couleur et forme :White PowderMasse moléculaire :393.96Ropivacaine
CAS :<p>Ropivacaine (LEA-103 HCl) is a local anaesthetic drug belonging to the amino amide group.</p>Formule :C17H26N2ODegré de pureté :97.75% - >99.99%Couleur et forme :SolidMasse moléculaire :274.40Oxybutynin
CAS :<p>Oxybutynin (Ditropan) is a synthetic anticholinergic agent that is used for treatment of urinary incontinence and overactive bladder syndrome.</p>Formule :C22H31NO3Degré de pureté :97.81% - 99.57%Couleur et forme :White To Off-White Crystalline PowderMasse moléculaire :357.49Butamben
CAS :<p>Butamben (Butyl 4-aminobenzoate) is a long-duration local anesthetic used for the treatment of chronic pain.</p>Formule :C11H15NO2Degré de pureté :99.43%Couleur et forme :Crystals From Alc Physical Description Yellow Powder Insoluble In Water (Ntp 1992)Masse moléculaire :193.24Mefloquine
CAS :<p>Mefloquine (Ro 215998), a quinoline antimalarial agent, is an anti-SARS-CoV-2 entry inhibitor.</p>Formule :C17H16F6N2ODegré de pureté :99.89%Couleur et forme :SolidMasse moléculaire :378.31N-Acetylprocainamide
CAS :<p>N-Acetylprocainamide (NAPA), the N-acetylated metabolite of Procainamide, is a Class III antiarrhythmic agent, while procainamide is a Class Ia antiarrhythmic</p>Formule :C15H23N3O2Degré de pureté :99.65% - 99.74%Couleur et forme :SolidMasse moléculaire :277.36VU591 hydrochloride
CAS :<p>VU591 hydrochloride is a selective Kir1.1 (ROMK) blocker with IC50 of 0.24 μM, not affecting Kir7.1, Kir2.1, Kir2.3, or Kir4.1, similar to VU 590.</p>Formule :C16H13ClN6O5Degré de pureté :98.93% - 99.22%Couleur et forme :SolidMasse moléculaire :404.76Ifenprodil Tartrate
CAS :<p>Ifenprodil is a selective NMDA receptor (glutamate) antagonist.</p>Formule :C21H27NO2C4H6O6Degré de pureté :99.02% - 99.55%Couleur et forme :SolidMasse moléculaire :400.49NS8593 hydrochloride
CAS :<p>NS8593 hydrochloride (NS8593 HCl) is a potent and selective inhibitor of small conductance Ca2+-activated K+ channels (SK channels) .</p>Formule :C17H18ClN3Degré de pureté :99.77%Couleur et forme :SolidMasse moléculaire :299.8Bupivacaine hydrochloride
CAS :<p>Bupivacaine hydrochloride (Vivacaine) is a long-lasting, amide local anesthetic that blocks sodium channels, inhibiting nerve impulses and sensation.</p>Formule :C18H28N2O·HClDegré de pureté :99.9% - >99.99%Couleur et forme :SolidMasse moléculaire :324.89Astemizole
CAS :<p>Astemizole (Laridal) is a long-acting antihistamine for allergies like rhinitis and asthma, with fewer anticholinergic effects.</p>Formule :C28H31FN4ODegré de pureté :98.24% - 99.67%Couleur et forme :White Crystals SolidMasse moléculaire :458.57Rosuvastatin calcium
CAS :<p>Rosuvastatin calcium (ZD4522) , a selective and competitive inhibitor of hepatic hydroxymethyl-glutaryl coenzyme A (HMG-CoA) reductase, has antilipidemic</p>Formule :(C22H27FN3O6S)CaDegré de pureté :98.21% - 99.68%Couleur et forme :White To Off-White Crystalline SolidMasse moléculaire :1001.14Quinidine hydrochloride monohydrate
CAS :<p>Quinidine hydrochloride monohydrate is an optical isomer of quinine. Quinidine prolongs cellular action potential and decreases automaticity.</p>Formule :C20H27ClN2O3Degré de pureté :94.4% - 99.68%Couleur et forme :SolidMasse moléculaire :378.89Dequalinium chloride
CAS :<p>Dequalinium chloride: topical bacteriostat, blocks apamin-sensitive K+ channels, used for wounds, oral infections, potential antifungal, risk of skin ulcers.</p>Formule :C30H40Cl2N4Degré de pureté :99.79% - 99.9%Couleur et forme :SolidMasse moléculaire :527.59Minoxidil
CAS :<p>Minoxidil (U10858) is an orally administered vasodilator with hair growth stimulatory and antihypertensive effects.</p>Formule :C9H15N5ODegré de pureté :99.885% - >99.99%Couleur et forme :Crystals From Methanol-Acetonitrile SolidMasse moléculaire :209.251-EBIO
CAS :<p>1-EBIO (1-EBIO) is a calium channel agonist.</p>Formule :C9H10N2ODegré de pureté :98.75%Couleur et forme :SolidMasse moléculaire :162.19Linoleoyl glycine
CAS :<p>Linoleoyl glycine activates hKCNQ1/hKCNE1 channels, has analgesic properties, and is found in skin, spinal cord, and brain.</p>Formule :C20H35NO3Degré de pureté :98.96%Couleur et forme :SolidMasse moléculaire :337.5Topiramate
CAS :<p>Topiramate (RWJ 17021) is a unique antiseizure medication that is used in the treatment of partial and generalized seizures.</p>Formule :C12H21NO8SDegré de pureté :99.79% - 99.92%Couleur et forme :White To Off-White Crystalline PowderMasse moléculaire :339.36NS3623
CAS :<p>NS3623 is an activator of human ether-a-go-go-related gene potassium channels.</p>Formule :C15H10BrF3N6ODegré de pureté :97.06%Couleur et forme :SolidMasse moléculaire :427.18Glipizide
CAS :<p>Glipizide (CP 28720) is a short-acting, second-generation sulfonylurea with hypoglycemic activity.</p>Formule :C21H27N5O4SDegré de pureté :99.67% - 99.75%Couleur et forme :SolidMasse moléculaire :445.54VU0134992 hydrochloride
CAS :<p>VU0134992 hydrochloride is the first subtype-preferring, orally active and selective blocker of Kir4.1 potassium channel pore(IC50 : 0.97 μM).</p>Formule :C20H32BrClN2O2Degré de pureté :>99.99%Couleur et forme :SolidMasse moléculaire :447.84NS13001
CAS :<p>NS13001, an oral SK channel modulator, shows promise for SCA2 therapy; EC50: 1.8 µM (SK2), 0.14 µM (SK3).</p>Formule :C17H16ClN7Degré de pureté :99.55%Couleur et forme :SolidMasse moléculaire :353.81Terfenadine
CAS :<p>Terfenadine, metabolized to fexofenadine by CYP3A4, is a non-sedative antihistamine targeting H1 receptors.</p>Formule :C32H41NO2Degré de pureté :98.76% - 99.75%Couleur et forme :SolidMasse moléculaire :471.67Mefloquine hydrochloride
CAS :<p>Mefloquine hydrochloride (Mefloquin hydrochloride) is a quinoline derivative used for the prevention and therapy of P. falciparum malaria.</p>Formule :C17H17ClF6N2ODegré de pureté :99% - 99.74%Couleur et forme :Off-White To Yellow SolidMasse moléculaire :414.77Linopirdine
CAS :<p>Linopirdine (DuP 996) is a TRPV1 agonist.</p>Formule :C26H21N3ODegré de pureté :99.45% - 99.78%Couleur et forme :SolidMasse moléculaire :391.46Dronedarone hydrochloride
CAS :<p>Dronedarone hydrochloride (SR33589) is an amiodarone analog which has an effective and promising treatment for Atrial fibrillation.</p>Formule :C31H44N2O5S·HClDegré de pureté :99.61%Couleur et forme :SolidMasse moléculaire :593.22Minocycline hydrochloride
CAS :<p>Minocycline HCl: tetracycline antibiotic, treats bacterial infections and acne, may cause acute or chronic hepatitis.</p>Formule :C23H28ClN3O7Degré de pureté :99.28% - >99.99%Couleur et forme :Bright Yellow-Orange Amorphous Solid Crystalline YellowMasse moléculaire :493.94Gliclazide
CAS :<p>Gliclazide (SE1702), an oral antihyperglycemic agent, belongs to the sulfonylurea class of insulin secretagogues, which act by stimulating beta-cells of the</p>Formule :C15H21N3O3SDegré de pureté :99.58%Couleur et forme :SolidMasse moléculaire :323.41NS19504
CAS :<p>NS19504 is an activator of Ca2+-activated K+ channel with EC50 of 11.0 µM.</p>Formule :C10H9BrN2SDegré de pureté :99.87%Couleur et forme :SolidMasse moléculaire :269.16Propafenone
CAS :<p>Propafenone: a drug for ventricular arrhythmias with mild beta-blocker activity, prolongs refractory period, and reduces heart automaticity.</p>Formule :C21H27NO3Degré de pureté :99.02%Couleur et forme :SolidMasse moléculaire :341.44Proflavine Hemisulfate
CAS :<p>Proflavine Hemisulfate (3,6-Diaminoacridine hemisulfate) is the hemisulfate salt of proflavine, an acridine-derived fluorescent contrast and disinfectant agent.</p>Formule :C13H12N3O2S0Degré de pureté :99.55%Couleur et forme :Orange To Red PowderMasse moléculaire :258.29ML418
CAS :<p>ML418 is a potent, selective and CNS penetrating Kir7.1 potassium channel blocker (IC50 = 310 nM), and also potently inhibits Kir6.2/SUR1.</p>Formule :C19H24ClN3O3Degré de pureté :99.3%Couleur et forme :SolidMasse moléculaire :377.87Clofilium tosylate
CAS :<p>Clofilium tosylate is a potassium channel blocker, induces apoptosis on human promyelocytic leukemia (HL-60) cells.</p>Formule :C28H44ClNO3SDegré de pureté :99.68%Couleur et forme :SolidMasse moléculaire :510.17Phenformin hydrochloride
CAS :<p>Phenformin hydrochloride (Phenformin HCl) is an agent belonging to the biguanide class of antidiabetics with antihyperglycemic activity.</p>Formule :C10H16ClN5Degré de pureté :97.11% - 99.80%Couleur et forme :Lactic AcidosisMasse moléculaire :241.72Eleclazine hydrochloride
CAS :<p>Eleclazine hydrochloride (GS 6615 hydrochloride) is a novel inhibitor of late Na+ current (IC50: 0.7 uM).</p>Formule :C21H17ClF3N3O3Degré de pureté :99.86%Couleur et forme :SolidMasse moléculaire :451.83BMS-191095
CAS :<p>BMS-191095 is mitochondrial ATP-sensitive potassium (mitoKATP) channel activator.</p>Formule :C22H21ClN4O2Degré de pureté :>99.99%Couleur et forme :SolidMasse moléculaire :408.88Hydroxyhexamide
CAS :<p>Hydroxyhexamide ((±)-Hydroxyhexamid) is a pharmacologically active metabolite of Acetohexamide, used as a hypoglycemic agent.</p>Formule :C15H22N2O4SDegré de pureté :98.91%Couleur et forme :SolidMasse moléculaire :326.41Brompheniramine maleate
CAS :<p>Brompheniramine maleate (Dimotane) is an antagonist against histamine H1 receptors.</p>Formule :C16H19BrN2·C4H4O4Degré de pureté :99.80%Couleur et forme :Crystal PowderMasse moléculaire :435.31AZD 7009
CAS :<p>AZD 7009 is a novel antiarrhythmic compound that inhibits the sodium current of hNav1.5 in CHO K1 cells with an IC50 of 11 uM.</p>Formule :C23H34N4O5Degré de pureté :98.42% - 98.51%Couleur et forme :SoildMasse moléculaire :446.54Tolbutamide
CAS :<p>Tolbutamide (HLS 831) is a sulphonylurea hypoglycemic agent with actions and uses similar to those of CHLORPROPAMIDE.</p>Formule :C12H18N2O3SDegré de pureté :99.80% - 99.93%Couleur et forme :White Crystalline PowderMasse moléculaire :270.35Miconazole
CAS :<p>Miconazole (R18134) is an imidazole antifungal agent that is used topically and by intravenous infusion.</p>Formule :C18H14Cl4N2ODegré de pureté :98% - >99.99%Couleur et forme :SolidMasse moléculaire :416.13Flufenamic acid
CAS :<p>Flufenamic acid (Arlef) is an anthranilic acid derivative with analgesic, anti-inflammatory, and antipyretic properties.</p>Formule :C14H10F3NO2Degré de pureté :98.68%Couleur et forme :White To Light Yellow Crystalline PowderMasse moléculaire :281.23NS5806
CAS :<p>NS5806 activates K+ currents, slows KV4.2/4.3 decay with KChIP2, and boosts KV4.3/KChIP2 peaks (EC50=5.3μM).</p>Formule :C16H8Br2F6N6ODegré de pureté :97.95%Couleur et forme :SolidMasse moléculaire :574.07BMS-394136
CAS :<p>BMS-394136 (BMS 394136) is a KV1.5 antagonist for the treatment of cardiovascular diseases such as arrhythmias and atrial fibrillation.</p>Formule :C24H21Cl2FN4ODegré de pureté :98.19% - 98.67%Couleur et forme :SolidMasse moléculaire :471.35DCEBIO
CAS :<p>DCEBIO, a 1-EBIO derivative, enhances Cl- secretion via hIK1 K+ channel and apical conductance in T84 cells.</p>Formule :C9H8Cl2N2ODegré de pureté :99.89%Couleur et forme :SolidMasse moléculaire :231.08IK1 inhibitor PA-6
CAS :<p>IK1 inhibitor PA-6 (PA-6) is a selective and potent inhibitor of IK1 (KIR2.x ion-channel-carried inward rectifier current)(IC50 of 12-15 nM for human and mouse</p>Formule :C31H32N4O2Degré de pureté :98.9%Couleur et forme :SolidMasse moléculaire :492.61Ketanserin
CAS :<p>Ketanserin: quinazoline derivative, 5-HT2 receptor antagonist, may lower blood pressure and inhibit blood clots.</p>Formule :C22H22FN3O3Degré de pureté :99.19% - 99.73%Couleur et forme :SolidMasse moléculaire :395.43Tipepidine hydrochloride
CAS :<p>Tipepidine hydrochloride: reversible DA D2 receptor inhibitor, IC50 7.0 μM, with antidepressant effects.</p>Formule :C15H18ClNS2Degré de pureté :99.97%Couleur et forme :SolidMasse moléculaire :311.89Tannic acid
CAS :<p>Tannic acid (Gallotannic acid) is a novel hERG channel blocker.</p>Formule :C76H52O46Degré de pureté :AR - ARCouleur et forme :Light Yellow To Light Brown Solid Solid Particulate/PowderMasse moléculaire :1701.2Hydrochlorothiazide
CAS :<p>Hydrochlorothiazide (HCTZ) 是一种口服有效的噻嗪类的利尿药，可抑制转化 TGF-β/Smad 信号通路。它通过打开钙激活钾 (KCA) 通道发挥直接的血管松弛作用。它改善心脏功能，减少纤维化并具有降压作用。</p>Formule :C7H8ClN3O4S2Degré de pureté :99.43% - 99.50%Couleur et forme :Crystals Physical Description Crystals Or White Powder (Ntp 1992)Masse moléculaire :297.74DCPIB
CAS :<p>DCPIB, a known specific and potent inhibitor of volume-regulated anion channels (VRAC),DCPIB displayed superior selectivity toward TRESK with an IC50 of 0.14 μM</p>Formule :C22H28Cl2O4Degré de pureté :99.79% - 99.87%Couleur et forme :SolidMasse moléculaire :427.36VU6036720
<p>VU6036720 is a potent and selective inhibitor of the isomeric Kir4.1/5.1.VU6036720 inhibits Kir4.1/5.1 activity by decreasing the channel open-circuit</p>Formule :C20H22ClFN4O2SDegré de pureté :98.1%Couleur et forme :SoildMasse moléculaire :436.93VU591
CAS :<p>VU591 is a selective extra-renal potassium channel inhibitor with an IC₅₀ of 0.24 μM.</p>Formule :C16H12N6O5Degré de pureté :99.29% - 99.53%Couleur et forme :SolidMasse moléculaire :368.3Cloperastine hydrochloride
CAS :<p>Cloperastine hydrochloride (HT-11 hydrochloride) is a type of flavonoid.</p>Formule :C20H25Cl2NODegré de pureté :97.74% - 99.42%Couleur et forme :SolidMasse moléculaire :366.33ICA-27243
CAS :<p>ICA-27243: Potent KCNQ2/Q3 opener, oral, EC50 0.38 μM; less effective on KCNQ4, KCNQ3/Q5; antiepileptic.</p>Formule :C12H7ClF2N2ODegré de pureté :99.54%Couleur et forme :SolidMasse moléculaire :268.65Repaglinide
CAS :<p>Repaglinide, a benzoic acid derivative, stimulates insulin, treats type 2 diabetes, and may rarely cause acute liver injury.</p>Formule :C27H36N2O4Degré de pureté :99.73% - >99.99%Couleur et forme :White To Off-White SolidMasse moléculaire :452.594-Aminopyridine
CAS :<p>4-Aminopyridine (Dalfampridine) is a nonselective potassium (K+) channel blocker that binds to the cytoplasmic side of the cell membrane.</p>Formule :C5H6N2Degré de pureté :91.61%Couleur et forme :SolidMasse moléculaire :94.11Glibenclamide
CAS :<p>Glibenclamide (Glyburide) is an antidiabetic sulfonylurea derivative with actions similar to those of chlorpropamide.</p>Formule :C23H28ClN3O5SDegré de pureté :99.05% - 99.75%Couleur et forme :SolidMasse moléculaire :494.00Flindokalner
CAS :<p>Flindokalner (BMS-204352) modulates potassium channels, enhances Kv7 subtypes and BKca, inhibits Kv7.1 (Ki=3.7μM), GABAA; has anxiolytic effects in vivo.</p>Formule :C16H10ClF4NO2Degré de pureté :99.96%Couleur et forme :SolidMasse moléculaire :359.7Ropivacaine hydrochloride
CAS :<p>Ropivacaine hydrochloride (Ropivacaine monohydrochloride) is the hydrochloride salt of ropivacaine, a local anesthetic of the amide type with analgesic activity</p>Formule :C17H26N2O·HClDegré de pureté :99.85% - 99.95%Couleur et forme :SolidMasse moléculaire :310.86Doxapram hydrochloride hydrate
CAS :<p>Doxapram hydrochloride hydrate (Doxapram HCl) inhibits TASK-1, TASK-3, TASK-1/TASK-3 heterodimeric channel function with EC50 of 0.41, 37, 9 μM, respectively.</p>Formule :C24H33ClN2O3C24H30N2O2·ClH·H2ODegré de pureté :99.64% - >99.99%Couleur et forme :SolidMasse moléculaire :432.99Diazoxide
CAS :<p>Diazoxide (Proglycem) is a benzothiadiazine derivative that is a peripheral vasodilator used for hypertensive emergencies.</p>Formule :C8H7ClN2O2SDegré de pureté :99% - 99.83%Couleur et forme :SolidMasse moléculaire :230.67Amiodarone hydrochloride
CAS :<p>Amiodarone HCl: Antianginal, class III antiarrhythmic. Lengthens heart muscle action, slows heart rate, reduces vascular resistance.</p>Formule :C25H29I2NO3·HClDegré de pureté :99.82% - ≥95%Couleur et forme :White To Cream Crystalline PowderMasse moléculaire :681.78Halothane
CAS :<p>Halothane (Anestan) 可以减弱内皮依赖性舒张作用。</p>Formule :C2HBrClF3Degré de pureté :98.50% - >99.99%Couleur et forme :Colorless Volatile Liquid Density 1 875 G / Cm3 Boiling Point 122 4°F (50 2°C) NoncombustibleMasse moléculaire :197.38Disopyramide
CAS :<p>Disopyramide, or Triombrin, a class I anti-arrhythmic with membrane-stabilizing effects, has heart depressant, anticholinergic, and anesthetic properties.</p>Formule :C21H29N3ODegré de pureté :99.62%Couleur et forme :SolidMasse moléculaire :339.47Quinine
CAS :<p>Quinine is a natural cinchona alkaloid that has been used for centuries in the prevention and therapy of malaria.</p>Formule :C20H24N2O2Degré de pureté :99.93% - 99.97%Couleur et forme :White Solid PowderMasse moléculaire :324.42AmmTX3
<p>KV4 channel blocker that inhibits A-type K+ current in mouse neurons; requires DPP6 and DPP10 for effect.</p>Formule :C158H262N50O48S6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :3822.47MASP-2-IN-1
<p>MASP-2-IN-1 (Compound 77) is an inhibitor of mannan-binding lectin-associated serine proteases (MASP), specifically targeting MASP2 and MASP3, with IC50 values of 11.4 nM and 13.2 µM, respectively. It shows weak inhibitory activity on hERG with an IC50 of 175 µM. This compound exhibits poor stability in mouse plasma, with a half-life of 4.4 hours.</p>Formule :C22H21N7O3SCouleur et forme :SolidMasse moléculaire :463.512CHET3
CAS :<p>CHET3 is a highly selective allosteric activator for TASK-3-containing K2P channels. CHET3 has shown potent in vivo analgesic effects. Cost-effective and quality-assured.</p>Formule :C21H21N5O3SDegré de pureté :99.64% - >99.99%Couleur et forme :SoildMasse moléculaire :423.49Heteropodatoxin-1
<p>Heteropodatoxin-1 (HpTx1), a spider peptide toxin, acts as an inhibitor of the Kv4.2 current, while concurrently inhibiting Nav1.7 and activating Nav1.9</p>Formule :C168H238N46O51S6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :3910.35Tertiapin LQ
<p>Kir1.1 channel blocker, 250x selective; Kd: Kir1.1 (1.1 nM), Kir3.1/3.2 (274 nM), Kir3.1/3.4 (361 nM). Tertiapin-Q derivative.</p>Formule :C106H179N33O24S4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :2428.03GsAF-II
<p>GsAF-II is a peptide toxin that selectively blocks hERG1 subtype potassium channels through a voltage-dependent mechanism and impedes Nav1.x subtype sodium</p>Formule :C176H261N47O45S7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :3979.7Lei-Dab7
CAS :Selective KCa2.2 channel blocker with Kd 3.8 nM, >200-fold specificity, enhances LTP, convulsive in vivo.Formule :C141H236N46O39S6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :3392.06Guangxitoxin 1E
CAS :<p>Guangxitoxin 1E acts as a gating modifier since it shifts the voltage-dependence of Kv2.1 K+ currents towards depolarized potentials.</p>Formule :C178H248N44O45S7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :3948.61BeKm-1
CAS :<p>Potent, selective hERG (KV11.1) blocker; doesn't affect 14 other K+ channels; extends QTc in rabbit heart dose-dependently.</p>Formule :C174H261N51O52S6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :4091.65Phe-Met-Arg-Phe, amide
CAS :<p>Phe-Met-Arg-Phe amide activates K+ current in neurons (ED50=23 nM), co-localizes with neuropeptide Y in brain regions.</p>Formule :C29H42N8O4SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :598.76Aekatperone
<p>Aekatperone, a reversible KATP channel inhibitor, exhibits an IC50 of 9 μM. It is utilized in research related to congenital hyperinsulinism (CHI).</p>Formule :C20H25N5O2SCouleur et forme :SolidMasse moléculaire :399.51Ion Channel Targeted Library
<p>A unique collection of 931 compounds targeting ion channels for research in ion channels-related diseases and ion channel drug discovery;</p>Couleur et forme :Odour SolidADWX 1 TFA
<p>ADWX 1 TFA is a novel peptide that potently targets and inhibits the Kv1.3 channel, with an IC50 of 1.89 pM. It specifically suppresses the activity of the Kv1.3 channel, in addition to inhibiting initial calcium signaling and NF-κB activation. This compound has been shown to ameliorate symptoms in rats with experimental autoimmune encephalomyelitis (EAE). ADWX 1 TFA is utilized in research focused on T-cell-mediated autoimmune diseases.</p>Formule :C169H281N57O46S7·xC2HF3O2Couleur et forme :SolidMasse moléculaire :4071.85 (free base)Apamin acetate
<p>Apamin acetate: Selective Ca2+-activated K+ channel blocker, 18-amino acid bee venom peptide, promotes synapse repair, anti-inflammatory.</p>Degré de pureté :96.97%Couleur et forme :SolidPinacidil monohydrate
CAS :<p>Pinacidil monohydrate is a potassium channel activator, antihypertensive drug.</p>Formule :C13H21N5ODegré de pureté :99.94% - 99.98%Couleur et forme :PowderMasse moléculaire :263.344-Hydroxytolbutamide
CAS :<p>4-Hydroxytolbutamide is a drug metabolite derived from the metabolism of Tolbutamide by CYP2C8 and CYP2C9 a sulfonylurea hypoglycemic agent.</p>Formule :C12H18N2O4SDegré de pureté :98%Couleur et forme :White To Off-WhiteMasse moléculaire :286.35Mesoridazine Besylate
CAS :<p>Mesoridazine Besylate (Serentil), a piperidine antipsychotic and phenothiazine, treats schizophrenia; it's a thioridazine metabolite.</p>Formule :C27H32N2O4S3Degré de pureté :99.58%Couleur et forme :SolidMasse moléculaire :544.75Dalazatide HCl
<p>Dalazatide HCl is a peptide and specific Kv1.3 inhibitor that suppresses the activation and proliferation of memory effector T cells,</p>Couleur et forme :SolidMasse moléculaire :4317.53 (Free base)Charybdotoxin
CAS :<p>Specific inhibitor of the big conductance Ca2+-activated K+ channel.</p>Formule :C176H277N57O55S7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :4295.95Margatoxin
CAS :<p>KV1.3 channel blocker, IC50 36 pM, no effect on calcium-activated channels, hinders VEGF-induced Ca++ influx & NO in endothelial cells.</p>Formule :C178H286N52O50S7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :4178.96Phe-Met-Arg-Phe amide trifluoroacetate
CAS :<p>Phe-met-arg-phe amide trifluoroacetate is an activator of K+ current with an ED50 of 23nm on the fundus nerve.</p>Formule :C33H44F6N8O8SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :826.81Apamin
CAS :<p>Apamin: 18-amino acid bee venom peptide, blocks SK channels, anti-inflammatory, anti-fibrotic, strongly basic.</p>Formule :C79H131N31O24S4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :2027.34Myomodulin
CAS :<p>Myomodulin is a neuropeptide present in molluscs, insects, and gastropods.Myomodulin is present in two identified aplysia neurons that contain myomodulin A the</p>Formule :C36H67N11O8S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :846.12Dendrotoxin K
CAS :<p>Dendrotoxin K blocks Kv1.1 channels, modulating glutamate release in CA3 neurons by controlling presynaptic spike timing.</p>Formule :C294H462N84O75S6Couleur et forme :SolidMasse moléculaire :6559.66RU-TRAAK-2
CAS :<p>RU-TRAAK-2 reversibly inhibits TWIK-related K+ channel, inactive on Kv1.2, GIRK2, Slo1.</p>Formule :C19H17N3OSDegré de pureté :99.81%Couleur et forme :SolidMasse moléculaire :335.42GsAF-I
<p>GsAF-I is a potent blocker of Na_v and hERG1 channels, exhibiting half-maximal inhibitory concentrations (IC50s) of 0.36 μM (Na_v 1.1), 0.6 μM (Na_v 1.2), 1.28</p>Formule :C160H244N46O42S7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :3708.39HG1 Toxin
<p>HG1 Toxin is a peptide found in the venom of the scorpion Heterometrus fulvipes, known for its ability to inhibit the potassium channel Kv1.3 (potassium channel Kv1.3). Additionally, HG1 Toxin exhibits trypsin inhibitory activity (Ki=107 nM), making it useful for research into autoimmune diseases.</p>Formule :C337H503N103O97S6Masse moléculaire :7736.59176Potassium Channel Targeted Library
<p>A unique collection of xnum potassium channel blockers and agonists for high throughput and high content screening;</p>Couleur et forme :Odour SolidADWX 1
<p>Potent KV1.3 blocker, IC50: 0.0019 nM; less effective on KV1.1. Curbs CD4+ T cell activation; eases rat multiple sclerosis model.</p>Formule :C169H281N57O46S7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :4071.86Cesium chloride
CAS :<p>Cesium chloride (CsCl) is considered to be the most toxic of the alkali chlorides, inhibiting fungal growth.</p>Formule :ClCsDegré de pureté :98%Couleur et forme :White Solid CrystallineMasse moléculaire :168.36Agitoxin-2
CAS :<p>Potent Shaker K+ channel blocker (Ki = 0.64 nM). Also inhibits Kv1.3, Kv1.6 and Kv1.1 K+ channels (Ki values are 4, 37 and 44 pM respectively).</p>Formule :C169H278N54O48S8Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :4090.87KV1.3-IN-1
<p>KV1.3-IN-1 (Compound trans-18), a selective KV1.3 channel inhibitor with IC50 values of 230 nM in Ltk cells and 26.12 nM in PHA-activated T-lymphocytes,</p>Formule :C23H30N2O4SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :430.56Guanfu base A
CAS :<p>Guanfu base A is a potent noncompetitive CYP2D6 inhibitor (Ki: 1.20 μM in HLMs; Ki: 0.37 μM for rCYP2D6). It also inhibits HERG channel current.</p>Formule :C24H31NO6Degré de pureté :99.71% - 99.85%Couleur et forme :SolidMasse moléculaire :429.5Dendrotoxin K TFA
<p>Dendrotoxin K TFA, a Kv1.1 channel blocker, modulates glutamate release in CA3 neurons by time-dependently regulating the presynaptic spike waveform [1].</p>Formule :C294H462N84O75S6·XC2HF3OC2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :6559.66 (free base)BKCa activator-1
<p>BKCa activator-1 (Compound 51b) is an orally active activator of BKCa calcium-activated potassium channels with an EC50 of 2.82 μM. It promotes K+ efflux, leading to cell membrane hyperpolarization and inhibition of smooth muscle contraction. In a spontaneous hypertensive rat (SHR) model, it alleviates urinary incontinence and exhibits antitussive effects in a guinea pig cough model.</p>Formule :C22H23F7N2O3Couleur et forme :SolidMasse moléculaire :496.418Ebio3
<p>Ebio3 is a selective potassium ion channel (KCNQ2) inhibitor with an IC50 of 1.2 nM. It binds to the KCNQ2 channel via its hydrophobic tail, causing the inward movement of the S6 helix, which results in the closure of the internal gate. The inhibitory effect of Ebio3 is equally effective on pathogenic KCNQ2 mutants, such as R75C and I238L, reducing their outward current by approximately 80%. Ebio3 holds potential for research in neurological disorders like epilepsy.</p>Formule :C19H23F2N3O2Couleur et forme :SolidMasse moléculaire :363.4KNa1.1-IN-2
CAS :<p>KNa1.1-IN-2 (Compound Z05) is a selective KNa1.1 channel inhibitor capable of penetrating the blood-brain barrier, and exhibits significant efficacy on hERG channels. It binds to KNa1.1 channels, effectively blocking channel activity caused by Gain-of-function (GOF) mutations, thus intervening in KCNT1-related seizures. Additionally, it inhibits the GOF mutant Y796H, making KNa1.1-IN-2 a promising candidate for research into KCNT1-associated epilepsy disorders.</p>Formule :C24H27NOCouleur et forme :SolidMasse moléculaire :345.48Vesnarinone HCl
<p>Vesnarinone HCl is an oral PDE3 inhibitor improving heart contractility, affecting calcium and potassium flux. Used in heart failure research.</p>Formule :C22H26ClN3O4Degré de pureté :99.17%Couleur et forme :SoildMasse moléculaire :431.91Ebio2
<p>Ebio2 is an effective activator of KCNQ2.</p>Formule :C17H19F2N3O2Couleur et forme :SolidMasse moléculaire :335.349Iberiotoxin
CAS :<p>Selective blocker of the big conductance Ca2+-activated K+ channel.</p>Formule :C179H274N50O55S7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :4230Cromakalim
CAS :<p>Cromakalim (BRL 34915) is an ATP-dependent K(+) channel opener, a smooth muscle relaxant with antiepileptic activity.</p>Formule :C16H18N2O3Degré de pureté :99.39%Couleur et forme :SolidMasse moléculaire :286.33Nateglinide D5
CAS :<p>Nateglinide D5 is a deuterium labeled Nateglinide.</p>Formule :C19H27NO3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :322.45QO-58
CAS :<p>QO-58 is a novel Kv7 activator (opener) that activates neuronal Kv7/KCNQ/M channels, danti-nociceptive effects on inflammatory pain</p>Formule :C18H8Cl2F4N4ODegré de pureté :99.17%Couleur et forme :SolidMasse moléculaire :443.18Flecainide
CAS :<p>Flecainide is an orally administered antiarrhythmic agent acting as a sodium channel blocker and IKr inhibitor,PSVT.</p>Formule :C17H20F6N2O3Degré de pureté :99.896%Couleur et forme :SolidMasse moléculaire :414.34Neosolaniol
CAS :<p>Neosolaniol, a type A trichothecene mycotoxin produced by Fusarium species, strongly induces an anorectic (loss of appetite) response.</p>Formule :C19H26O8Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :382.4KCNQ1 activator-1
CAS :<p>N-[4-(4-Methoxyphenyl)-2-thiazolyl]-2-piperidinecarboxamide is a potent KCNQ1 activator for LQTS research.</p>Formule :C22H23N3O4S2Degré de pureté :99.71%Couleur et forme :SolidMasse moléculaire :457.57Endoxifen Z-isomer hydrochloride
CAS :<p>Endoxifen Z-isomer hydrochloride (Endoxifen HCl) is the active metabolite of Tamoxifen, which is an effective and selective estrogen receptor antagonist.</p>Formule :C25H28ClNO2Couleur et forme :SolidMasse moléculaire :409.95Clamikalant sodium
CAS :<p>Clamikalant sodium (HMR 1098) is an ATP-dependent potassium channel (KATP) cardiac-selective blocker, used in the study of arrhythmias.</p>Formule :C19H21ClN3NaO5S2Degré de pureté :99.95%Couleur et forme :SolidMasse moléculaire :493.96Oxypeucedanin
CAS :<p>1.</p>Formule :C16H14O5Degré de pureté :98.66% - 98.85%Couleur et forme :SolidMasse moléculaire :286.28Ibutilide Fumarate
CAS :<p>Ibutilide Fumarate is a class III antiarrhythmic, prolonging action potentials by enhancing sodium influx, and can extend QT interval.</p>Formule :(C20H36N2O3S)2·C4H4O4Degré de pureté :99.68% - 99.74%Couleur et forme :SolidMasse moléculaire :885.23Guanosine 5'-diphosphate disodium salt
CAS :<p>5'-GDP-Na2: a nucleoside diphosphate, iron mobilizer, blocks hepcidin-ferroportin, affects IL-6/stat-3.</p>Formule :C10H13N5Na2O11P2Degré de pureté :99.40%Couleur et forme :White PowderMasse moléculaire :487.16XE 991 dihydrochloride
CAS :<p>XE 991 dihydrochloride is a Kv7 (KCNQ) channel blocker.</p>Formule :C26H22Cl2N2ODegré de pureté :98.68%Couleur et forme :SolidMasse moléculaire :449.37SKA-31
CAS :<p>SKA-31 (Naphtho[1,2-d]thiazol-2-ylamine) is an activator of KCa3.1 and KCa2 channels (EC50s: 260, 2900, 2900 nM for KCa3.1, KCa2.1 and KCa2.2 respectively).</p>Formule :C11H8N2SDegré de pureté :99.38%Couleur et forme :SolidMasse moléculaire :200.26Ropivacaine hydrochloride monohydrate
CAS :<p>Ropivacaine hydrochloride monohydrate (LEA-103 HCl) is an anaesthetic agent and blocks impulse conduction through inhibiting sodium ion influx reversibly.</p>Formule :C17H29ClN2O2Degré de pureté :99.94% - 99.95%Couleur et forme :White SolidMasse moléculaire :328.88Cholesterol myristate
CAS :<p>Cholesterol myristate, a natural steroid in Chinese medicine, affects GABAA, nicotinic receptors, and potassium channels.</p>Formule :C41H72O2Degré de pureté :99.65%Couleur et forme :SolidMasse moléculaire :597.01Quinidine sulfate dihydrate
CAS :<p>Quinidine sulfate dihydrate (Pitayine Sodium) is a potent and selective cytochrome P450db inhibitor</p>Formule :C40H54N4O10SDegré de pureté :99.85%Couleur et forme :White To Light Yellow Crystal PowdeMasse moléculaire :782.9ML277
CAS :<p>ML277 (CID-53347902) was identified as a potent activator of KCNQ1 channels (EC(50)=260 nM).</p>Formule :C23H25N3O4S2Degré de pureté :99.35%Couleur et forme :SolidMasse moléculaire :471.59APD668
CAS :<p>APD668 is a potent GPR119 agonist with EC50 of 2.7 nM and 33 nM for hGPR119 and ratGPR119, respectively.</p>Formule :C21H24FN5O5SDegré de pureté :99.74% - 99.97%Couleur et forme :SolidMasse moléculaire :477.51Amifampridine
CAS :<p>Amifampridine blocks nerve potassium channels, extends action potentials, boosts acetylcholine release, and treats rare muscle diseases.</p>Formule :C5H7N3Degré de pureté :99.82%Couleur et forme :Slightly Beige PowderMasse moléculaire :109.13TKIM
CAS :<p>TKIM is a TWIK-related potassium channel 1 (TREK-1) inhibitor, binding to the pocket of the intermediate (IM) state of TREK-1.</p>Formule :C18H14ClN3O2SDegré de pureté :99.47%Couleur et forme :SolidMasse moléculaire :371.84ICA-069673
CAS :<p>ICA-069673 is an activator of KCNQ2/Q3 potassium channel (IC50: 0.69 μM).</p>Formule :C11H6ClF2N3ODegré de pureté :99.04% - 99.68%Couleur et forme :SolidMasse moléculaire :269.63NS309
CAS :<p>NS309 activates SK/KCa2, IK/KCa3.1 (0.12-1.2 μM EC50, 10-90 nM EC50), and Kv11.1 channels; doesn't affect BK/KCa1.1; modulates neuronal firing.</p>Formule :C8H4Cl2N2O2Degré de pureté :97.55%Couleur et forme :SolidMasse moléculaire :231.04BAPTA-AM
CAS :<p>BAPTA-AM is a calcium chelator that is cell-permeable and selective, blocking hERG, hKv1.3, and hKv1.5 channels (IC50=1.3/1.45/1.23 μM).</p>Formule :C34H40N2O18Degré de pureté :98% - 99.47%Couleur et forme :White Powder Or Crystalline PowderMasse moléculaire :764.68Quinidine
CAS :<p>Quinidine is a stereoisomer of the antimalarial agent quinine and a class Ia antiarrhythmic agent. for the treatment of abnormal heart rhythms and also malaria.</p>Formule :C20H24N2O2Degré de pureté :97.03% - 99.99%Couleur et forme :Crystals With 2 5 Mol Water Of Crystallization; Crystals From Dilute Alcohol Physical Description Crystals Or White Powder (Ntp 1992)Masse moléculaire :324.42Talatisamine
CAS :<p>Talatisamine and TEA mitigate Aβ oligomer effects on I(K), bolstering cell survival and reducing K(+) loss-induced apoptosis; promising for further study.</p>Formule :C24H39NO5Degré de pureté :98.62% - 99.44%Couleur et forme :SolidMasse moléculaire :421.57VU0134992
CAS :<p>VU0134992 is an Kir4.1 blocker with an IC50 value of 0.97 μM</p>Formule :C20H31BrN2O2Degré de pureté :99.86%Couleur et forme :SolidMasse moléculaire :411.38Endoxifen (Z-isomer)
CAS :<p>Endoxifen Z-isomer (EDX) is a key active metabolite of tamoxifen with higher affinity and specificity to estrogen receptors that inhibits aromatase activity.</p>Formule :C25H27NO2Degré de pureté :99.19% - 99.81%Couleur et forme :SolidMasse moléculaire :373.49Paederosidic acid methyl ester
CAS :<p>Paederosidic acid methyl ester has antinociception, is possibly related to the pathway of NO-cGMP-ATP sensitive K(+) channels.</p>Formule :C19H26O12SDegré de pureté :99.67% - 99.91%Couleur et forme :SolidMasse moléculaire :478.4720(S)-Ginsenoside Rg3
CAS :<p>20(S)-Ginsenoside Rg3 (Rg3) possess an ability to inhibit the lung metastasis of tumor cells via inhibition of the adhesion and invasion of tumor cells.</p>Formule :C42H72O13Degré de pureté :98.11% - 99.93%Couleur et forme :SolidMasse moléculaire :785.01KCNQ2/3 activator-1
CAS :<p>KCNQ2/3 activator-1 is a Kv7.2/Kv7.3 (KCNQ2/3) potassium channel activator.</p>Formule :C23H29FN2ODegré de pureté :99.16% - 99.47%Couleur et forme :SolidMasse moléculaire :368.492,2,2-Trichloroethanol
CAS :<p>2,2,2-Trichloroethanol is an agonist of the nonclassical K2P channels TREK-1 and TRAAK.</p>Formule :C2H3Cl3ODegré de pureté :99.74%Couleur et forme :LiquidMasse moléculaire :149.4Yoda 1
CAS :<p>Yoda 1 is an agonist of the Piezo1 channel that agonizes human- and mouse-derived Piezo1. Yoda 1 is also an inhibitor of GlyT2. Cost-effective, quality assurance.</p>Formule :C13H8Cl2N4S2Degré de pureté :98% - 99.98%Couleur et forme :SolidMasse moléculaire :355.27Quinine hydrochloride dihydrate
CAS :<p>Quinine hydrochloride dihydrate (Quinine HCl Dihydrate) is a white crystalline K+ channel blocker, used to treat malaria.</p>Formule :C20H24N2O2·HCl·2H2ODegré de pureté :99.91%Couleur et forme :White To Light Yellow Crystal PowderMasse moléculaire :396.91Kv2-IN-A1
CAS :<p>Kv2-IN-A1 is an inhibitor of Kv2.1 and Kv2.2.</p>Formule :C20H17ClN4OSDegré de pureté :98.83%Couleur et forme :SolidMasse moléculaire :396.89Almitrine mesylate
CAS :<p>Almitrine mesylate targets Ca2+-dependent K+ channels in rat cells, used for chronic lung hypoxemia.</p>Formule :C28H37F2N7O6S2Degré de pureté :99.96%Couleur et forme :CoaMasse moléculaire :669.76Azimilide Dihydrochloride
CAS :<p>Azimilide Dihydrochloride (NE-10064 Dihydrochloride), a novel class III antiarrhythmic agent, blocks both the IKs and IKr with antiarrhythmic activity.</p>Formule :C23H30Cl3N5O3Degré de pureté :97.59% - ≥95%Couleur et forme :SolidMasse moléculaire :530.88ML365
CAS :<p>ML365 is a novel selective small molecule inhibitor of TASK1(KCNK3).</p>Formule :C22H20N2O3Degré de pureté :98.78%Couleur et forme :SolidMasse moléculaire :360.41VU0071063
CAS :<p>VU0071063 is a Kir6.2/SUR1 activator.</p>Formule :C18H22N4O2Degré de pureté :99.33%Couleur et forme :SolidMasse moléculaire :326.39Quinine dihydrochloride
CAS :<p>Quinine dihydrochloride (Quinine bimuriate) is a primary alkaloid of various species of Cinchona (Rubiaceae).</p>Formule :C20H26Cl2N2O2Degré de pureté :99.79% - 99.97%Couleur et forme :White SolidMasse moléculaire :397.34Sematilide hydrochloride
CAS :<p>Sematilide hydrochloride (CK-1752) is a class III antiarrhythmic. It is a selectively delayed rectifier K+ current (IKr) channel blocker.</p>Formule :C14H24ClN3O3SDegré de pureté :99.14%Couleur et forme :SolidMasse moléculaire :349.87Dofetilide
CAS :<p>Dofetilide (UK 68789), a class III antiarrhythmic sulfonamide, blocks Ikr cardiac channels, prolongs action potential, and treats atrial fibrillation/flutter.</p>Formule :C19H27N3O5S2Degré de pureté :97.85% - 99.06%Couleur et forme :Off-White Or Yellowish Crystalline PowderMasse moléculaire :441.56AUT1
CAS :<p>AUT1 (AUT-1) is a novel specific modulator of Kv3 channels (EC50: 4.7 and 4.9 uM for Kv3.1b and Kv3.2a).</p>Formule :C18H19N3O4Degré de pureté :99.8% - 99.95%Couleur et forme :SolidMasse moléculaire :341.36Iptakalim Hydrochloride
CAS :<p>Iptakalim, a lipophilic para-amino compound, is a novel ATP-sensitive potassium channel (KATP) opener, as well as an α4β2-containing nicotinic acetylcholine</p>Formule :C9H22ClNDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :179.731GSK369796 Dihydrochloride
CAS :<p>GSK369796 Dihydrochloride (N-tert-butylisoquine),is an anti-malaria drug candidate.</p>Formule :C20H24Cl3N3ODegré de pureté :>99.99%Couleur et forme :SolidMasse moléculaire :428.78PAP-1
CAS :<p>PAP-1 (5-(4-Phenoxybutoxy)psoralen) is a selective, and orally active Kv1.3 blocker (EC50: 2 nM).</p>Formule :C21H18O5Degré de pureté :99.35% - 99.75%Couleur et forme :White SolidMasse moléculaire :350.36Nigericin sodium salt
CAS :<p>Nigericin sodium salt, an antibiotic and NLRP3 activator from S. hygroscopicus, inhibits Golgi and gram-positive bacteria, blocking viral activation.</p>Formule :C40H67NaO11Degré de pureté :98.2% - 99.52%Couleur et forme :SolidMasse moléculaire :746.94Atpenin A5
CAS :<p>Atpenin A5 is a potent and highly specific complex II inhibitor (IC50 ~10 nM).</p>Formule :C15H21Cl2NO5Degré de pureté :97.33% - 99.91%Couleur et forme :SolidMasse moléculaire :366.24LY 303511 hydrochloride
CAS :<p>LY 303511 hydrochloride is a potent mTOR inhibitor</p>Formule :C19H19ClN2O2Degré de pureté :98.47%Couleur et forme :SolidMasse moléculaire :342.82Mitiglinide Calcium
CAS :<p>Mitiglinide Calcium (KAD-1229) is a blood glucose-lowering drugs, stimulating insulin secretion by closing the ATP-sensitive K+ channels in pancreatic beta-</p>Formule :(C19H24NO3)2·CaDegré de pureté :99.83%Couleur et forme :White Crystal PosderMasse moléculaire :668.88Flupirtine maleate
CAS :<p>Flupirtine maleate (Katadolon maleate), a centrally acting non-opioid analgesia, is the salt form of Flupirtine. Flupirtine is an NMDA receptor antagonist.</p>Formule :C15H17FN4O2·C4H4O4Degré de pureté :99.5% - 99.9%Couleur et forme :Off-White Crystalline PowderMasse moléculaire :420.39Senicapoc
CAS :<p>Senicapoc (ICA-17043) blocks Gardos channel, reduces RBC dehydration, IC50: 11 nM for rubidium flux, 30 nM for dehydration. Used in Sickle Cell therapy.</p>Formule :C20H15F2NODegré de pureté :95.7% - 99.47%Couleur et forme :SolidMasse moléculaire :323.34E-4031 dihydrochloride
CAS :<p>E-4031 is a methanesulfonanilide class III antiarrhythmic agent that prolongs cardiac action potential duration by blocking ERG K+ channels (IC50 = 29 nM)</p>Formule :C21H29Cl2N3O3SDegré de pureté :99.31% - 99.87%Couleur et forme :SolidMasse moléculaire :474.44Allocryptopine
CAS :<p>Allocryptopine (Thalictrimine) induces muscle contraction and relaxation in urinary bladder and ileum, respectively.</p>Formule :C21H23NO5Degré de pureté :99.41% - ≥95%Couleur et forme :SolidMasse moléculaire :369.41KS176
CAS :<p>KS176: selective BCRP inhibitor, potent against breast cancer drug resistance; ineffective on P-gp, MRP1.</p>Formule :C22H19N3O5Degré de pureté :99.61% - 99.61%Couleur et forme :SolidMasse moléculaire :405.45-Hydroxydecanoate sodium
CAS :<p>5-Hydroxydecanoate sodium: KATP channel blocker, IC50 ~30μM; mitochondrial substrate; antioxidant.</p>Formule :C10H19NaO3Degré de pureté :99.24% - 99.89%Couleur et forme :SolidMasse moléculaire :210.25VU0810464
CAS :<p>VU0810464 is a non-ureaG protein-gated inwardly-rectifying potassium channels (GIRK, Kir3) activator.</p>Formule :C18H21ClFN3ODegré de pureté :99.62%Couleur et forme :SolidMasse moléculaire :349.83Loureirin B
CAS :<p>Loureirin B suppresses fibrosis by modulating MMPs/TIMPs, hindering fibroblast growth, and targeting TGF-β1/Smad2/3 pathway.</p>Formule :C18H20O5Degré de pureté :99.33% - 99.86%Couleur et forme :SolidMasse moléculaire :316.35Mitiglinide calcium hydrate
CAS :<p>Mitiglinide calcium hydrate (S-21403 calcium hydrate) is a drug for the treatment of type 2 diabetes.</p>Formule :C38H52CaN2O8Degré de pureté :98.97% - 99.96%Couleur et forme :White SolidMasse moléculaire :704.91A2793
CAS :<p>A2793 is a dual inhibitor of TWIK-associated acid-sensitive K+ channel 1 (TASK-1)/TRESK, with an IC50 for mTRESK of 6.8 μM.</p>Formule :C13H12ClNO3Degré de pureté :98.54%Couleur et forme :SolidMasse moléculaire :265.69O-Nornuciferine
CAS :<p>O-Nornuciferine reveals distinct in vitro hERG blockages measured in HEK293 cells with the IC50 value of 2.89 uM.</p>Formule :C18H19NO2Degré de pureté :99.86%Couleur et forme :SolidMasse moléculaire :281.35ML213
CAS :<p>ML213 (CID-3111211) is a selective activator of Kv7.2 (KCNQ2) and Kv7.4 (KCNQ4) channels, enhances Kv7.2 and Kv7.4 channels with EC50s of 230 and 510 nM,</p>Formule :C17H23NODegré de pureté :>99.99%Couleur et forme :SolidMasse moléculaire :257.37Levcromakalim
CAS :<p>Levcromakalim (BRL 38227) is an activator of the ATP-sensitive K+ channel.</p>Formule :C16H18N2O3Degré de pureté :99.74%Couleur et forme :SolidMasse moléculaire :286.33NS 11021
CAS :<p>NS 11021 (NS11021) , a novel opener of large-conductance Ca(2+)-activated K(+) channels</p>Formule :C16H9BrF6N6SDegré de pureté :97.26%Couleur et forme :SolidMasse moléculaire :511.24Tetraethylammonium bromide
CAS :<p>Tetraethylammonium bromide (TEA bromide) can selectively block potassium channels.</p>Formule :C8H20BrNDegré de pureté :98%Couleur et forme :White SolidMasse moléculaire :210.16ML133 hydrochloride
CAS :<p>ML133 hydrochloride (ML133 HCl) is a selective potassium channel inhibitor for Kir2.1, has no effect on Kir1.1 and weak activity for Kir4.1 and Kir7.1.</p>Formule :C19H19NO·HClDegré de pureté :99.48%Couleur et forme :SolidMasse moléculaire :313.82SKF-96365 hydrochloride
CAS :<p>SKF-96365 hydrochloride (SKF96365) , a SOCE inhibitor, exhibits potent anti-neoplastic activity by inducing cell-cycle arrest and apoptosis in colorectal Y</p>Formule :C22H27ClN2O3Degré de pureté :99.47% - 99.92%Couleur et forme :SolidMasse moléculaire :402.91Rimtuzalcap
CAS :<p>Rimtuzalcap (CAD-1883), a selective modulator for SK channels, may treat movement disorders like SCA and ET.</p>Formule :C18H24F2N6ODegré de pureté :99.64%Couleur et forme :SolidMasse moléculaire :378.42A2764 dihydrochloride
CAS :<p>A2764 dihydrochloride is a highly selective inhibitor of TRESK.</p>Formule :C15H21Cl3N2ODegré de pureté :99.05%Couleur et forme :SolidMasse moléculaire :351.7(±)-Naringenin
CAS :<p>(±)-Naringenin (Naringenine) is a natural product.</p>Formule :C15H12O5Degré de pureté :98.06%Couleur et forme :SolidMasse moléculaire :272.25Dihydroberberine
CAS :<p>Dihydroberberine has anti-atherosclerotic, anti-inflammatory, hypolipidemic and antitumor activities.</p>Formule :C20H19NO4Degré de pureté :93.77%Couleur et forme :SolidMasse moléculaire :337.37Nateglinide
CAS :<p>Nateglinide is an oral drug for type 2 diabetes, stimulating insulin release; may cause rare acute liver injury.</p>Formule :C19H27NO3Degré de pureté :99.93% - 99.94%Couleur et forme :White Crystalline PowderMasse moléculaire :317.42Guanosine 5'-diphosphate
CAS :<p>Guanosine 5'-diphosphate (GDP) as Potential Iron Mobilizer, Preventing the Hepcidin-Ferroportin Interaction and Modulating the Interleukin-6/Stat-3 Pathway.</p>Formule :C10H15N5O11P2Degré de pureté :98.46% - 99.52%Couleur et forme :SolidMasse moléculaire :443.2ML 297
CAS :<p>ML 297 is a selective Kir3.1/3.2 (GIRK1/2) channel activator (IC50 values are 160, 887 and 914 nM for GIRK1/2, GIRK1/4 and GIRK1/3 respectively).</p>Formule :C17H14F2N4ODegré de pureté :97.85%Couleur et forme :SolidMasse moléculaire :328.32NS1643
CAS :<p>NS1643 is a potent human ether-a-go-go related gene (hERG) KV11.1 channel activator with EC50 of 10.5 μM.</p>Formule :C15H10F6N2O3Degré de pureté :98.37% - 99.31%Couleur et forme :SolidMasse moléculaire :380.24GAL-021
CAS :<p>GAL-021 an intravenous BKCa-channel blocker.</p>Formule :C11H22N6ODegré de pureté :97.71% - 99.66%Couleur et forme :SolidMasse moléculaire :254.33Daurisoline
CAS :<p>Daurisoline ((R,R)-Daurisoline) is a hERG inhibitor. Daurisoline is also an autophagy blocker.</p>Formule :C37H42N2O6Degré de pureté :98% - 99.96%Couleur et forme :Light Yellow PowderMasse moléculaire :610.74NS-1619
CAS :<p>NS1619 have cardio-protective effects after ischemia-reperfusion injury.</p>Formule :C15H8F6N2O2Degré de pureté :97.66% - 98%Couleur et forme :SolidMasse moléculaire :362.23GW9508
CAS :<p>GW9508(GW 9508) is a potent and selective agonist for FFA1 (GPR40), stimulates insulin secretion in a glucose-sensitive manner.</p>Formule :C22H21NO3Degré de pureté :97.89% - 99.19%Couleur et forme :SolidMasse moléculaire :347.41JNJ 303
CAS :<p>JNJ 303 is a potent blocker of IKs (IC50 : 64 nM).</p>Formule :C21H29ClN2O4SDegré de pureté :99.28%Couleur et forme :SolidMasse moléculaire :440.98TRAM-34
CAS :<p>TRAM-34 (Triarylmethane-34), an effective and specific inhibitor of the intermediate-conductance Ca2+-activated K+ channel, does not block cytochrome P450.</p>Formule :C22H17ClN2Degré de pureté :99.01% - 99.91%Couleur et forme :SolidMasse moléculaire :344.84ML335
CAS :<p>ML335 is a selective activator of TREK-1 and TREK-2.</p>Formule :C15H14Cl2N2O3SDegré de pureté :99.73% - 99.79%Couleur et forme :SolidMasse moléculaire :373.25ICA 110381
CAS :<p>ICA 110381 is a KCNQ2/Q3 potassium channel opener for the treatment of epilepsy</p>Formule :C12H8Cl2N2ODegré de pureté :97.72%Couleur et forme :SolidMasse moléculaire :267.11Flecainide hydrochloride
CAS :<p>Flecainide is a medication used to prevent and treat abnormally fast heart rates. This includes ventricular and supraventricular tachycardias.</p>Formule :C17H21ClF6N2O3Degré de pureté :97.79%Couleur et forme :SolidMasse moléculaire :450.81Minoxidil sulfate
CAS :<p>Minoxidil sulfate (U-58838) is the active metabolite required to exert the vasodilatory and hair growing effects of minoxidil.</p>Formule :C9H15N5O4SDegré de pureté :99.01% - 99.72%Couleur et forme :White Crystalline SolidMasse moléculaire :289.31ASP2905
CAS :<p>ASP-2905 is a potent and selective inhibitor of potassium channel Kv12.2 encoded by the Kcnh3/BEC1 gene.</p>Formule :C20H17FN8Degré de pureté :97.29%Couleur et forme :SolidMasse moléculaire :388.4AM-92016 hydrochloride
CAS :AM-92016 is a specific blocker of rectifier potassium current.Formule :C19H24Cl2N2O4S·HClDegré de pureté :98.68%Couleur et forme :SolidMasse moléculaire :483.84NS6180
CAS :<p>NS6180 is a potent and selective KCa3.1 channel inhibitor(IC50= 9 nM). It prevents T-cell activation and inflammation.</p>Formule :C16H12F3NOSDegré de pureté :99.83% - ≥95%Couleur et forme :SolidMasse moléculaire :323.33Tetraethylammonium chloride
CAS :<p>Tetraethylammonium chloride is a quaternary ammonium compound.</p>Formule :C8H20ClNDegré de pureté :≥95%Couleur et forme :White Solid Solid Particulate/PowderMasse moléculaire :165.7RY785
CAS :<p>RY785 is a potent and selective inhibitor of voltage-gated potassium channel such as KV2.2 (IC50 = 50 nM). RY785 may be used in pain relief studies.</p>Formule :C21H20N4O2SDegré de pureté :99.78%Couleur et forme :SolidMasse moléculaire :392.47Enflurane
CAS :<p>Enflurane (Efrane), a volatile anaesthetic, inhibits Ca2+-activated K+ channels and is used to gauge anesthesia levels in gas chromatography.</p>Formule :C3H2ClF5ODegré de pureté :99.64%Couleur et forme :Clear Colorless Liquid Ordinary Temperature And Pressure Bp 56 8°C Density 1 50 G Cm-3 At Room Temperature Used As AnMasse moléculaire :184.49SCH-23390 hydrochloride
CAS :<p>SCH-23390 hydrochloride (R-(+)-SCH23390 hydrochloride) is an effective dopamine receptor antagonist, and for the D1(Ki=0.2 nM) and D5(Ki=0.3 nM).</p>Formule :C17H19Cl2NODegré de pureté :98% - 99.83%Couleur et forme :SolidMasse moléculaire :324.24ICA-105574
CAS :<p>ICA-105574 activates hERG, enhancing peak current and shortening action potential, while modulating activation kinetics.</p>Formule :C19H14N2O4Degré de pureté :98.89%Couleur et forme :SolidMasse moléculaire :334.33Branaplam
CAS :<p>Branaplam (LMI 070) is a highly potent, selective and orally active small molecule SMN2 splicing modulator.</p>Formule :C22H27N5O2Degré de pureté :98.28% - 99.72%Couleur et forme :SolidMasse moléculaire :393.48
