Canal potassique
Les canaux potassiques sont un groupe diversifié de protéines membranaires qui facilitent le flux des ions potassium (K+) à travers la membrane cellulaire. Ces canaux jouent un rôle crucial dans le maintien du potentiel de membrane au repos, la régulation du volume cellulaire et le contrôle de l'excitabilité des neurones et des cellules musculaires. Les canaux potassiques sont impliqués dans divers processus physiologiques, y compris la régulation du rythme cardiaque, la sécrétion d'insuline et la libération de neurotransmetteurs. La dysrégulation des canaux potassiques est liée à des conditions telles que les arythmies, l'épilepsie et l'hypertension. Chez CymitQuimica, nous proposons une large gamme de modulateurs de canaux potassiques pour soutenir vos recherches en électrophysiologie, santé cardiovasculaire et neurobiologie.
276 produits trouvés pour "Canal potassique"
Trier par
Degré de pureté (%)
0
100
|
0
|
50
|
90
|
95
|
100
Gliclazide
CAS :<p>Gliclazide (SE1702), an oral antihyperglycemic agent, belongs to the sulfonylurea class of insulin secretagogues, which act by stimulating beta-cells of the</p>Formule :C15H21N3O3SDegré de pureté :99.58%Couleur et forme :SolidMasse moléculaire :323.41NS8593 hydrochloride
CAS :<p>NS8593 hydrochloride (NS8593 HCl) is a potent and selective inhibitor of small conductance Ca2+-activated K+ channels (SK channels) .</p>Formule :C17H18ClN3Degré de pureté :99.77%Couleur et forme :SolidMasse moléculaire :299.8N-Acetylprocainamide
CAS :<p>N-Acetylprocainamide (NAPA), the N-acetylated metabolite of Procainamide, is a Class III antiarrhythmic agent, while procainamide is a Class Ia antiarrhythmic</p>Formule :C15H23N3O2Degré de pureté :99.65% - 99.74%Couleur et forme :SolidMasse moléculaire :277.36Minocycline hydrochloride
CAS :<p>Minocycline HCl: tetracycline antibiotic, treats bacterial infections and acne, may cause acute or chronic hepatitis.</p>Formule :C23H28ClN3O7Degré de pureté :99.28% - >99.99%Couleur et forme :Bright Yellow-Orange Amorphous Solid Crystalline YellowMasse moléculaire :493.94Dequalinium chloride
CAS :<p>Dequalinium chloride: topical bacteriostat, blocks apamin-sensitive K+ channels, used for wounds, oral infections, potential antifungal, risk of skin ulcers.</p>Formule :C30H40Cl2N4Degré de pureté :99.79% - 99.9%Couleur et forme :SolidMasse moléculaire :527.59Bupivacaine hydrochloride
CAS :<p>Bupivacaine hydrochloride (Vivacaine) is a long-lasting, amide local anesthetic that blocks sodium channels, inhibiting nerve impulses and sensation.</p>Formule :C18H28N2O·HClDegré de pureté :99.9% - >99.99%Couleur et forme :SolidMasse moléculaire :324.89Flindokalner
CAS :<p>Flindokalner (BMS-204352) modulates potassium channels, enhances Kv7 subtypes and BKca, inhibits Kv7.1 (Ki=3.7μM), GABAA; has anxiolytic effects in vivo.</p>Formule :C16H10ClF4NO2Degré de pureté :99.96%Couleur et forme :SolidMasse moléculaire :359.7Mefloquine
CAS :<p>Mefloquine (Ro 215998), a quinoline antimalarial agent, is an anti-SARS-CoV-2 entry inhibitor.</p>Formule :C17H16F6N2ODegré de pureté :99.89%Couleur et forme :SolidMasse moléculaire :378.31Astemizole
CAS :<p>Astemizole (Laridal) is a long-acting antihistamine for allergies like rhinitis and asthma, with fewer anticholinergic effects.</p>Formule :C28H31FN4ODegré de pureté :98.24% - 99.67%Couleur et forme :White Crystals SolidMasse moléculaire :458.57Linopirdine
CAS :<p>Linopirdine (DuP 996) is a TRPV1 agonist.</p>Formule :C26H21N3ODegré de pureté :99.45% - 99.78%Couleur et forme :SolidMasse moléculaire :391.46Propafenone
CAS :<p>Propafenone: a drug for ventricular arrhythmias with mild beta-blocker activity, prolongs refractory period, and reduces heart automaticity.</p>Formule :C21H27NO3Degré de pureté :99.02%Couleur et forme :SolidMasse moléculaire :341.44Phenformin hydrochloride
CAS :<p>Phenformin hydrochloride (Phenformin HCl) is an agent belonging to the biguanide class of antidiabetics with antihyperglycemic activity.</p>Formule :C10H16ClN5Degré de pureté :97.11% - 99.80%Couleur et forme :Lactic AcidosisMasse moléculaire :241.72Brompheniramine maleate
CAS :<p>Brompheniramine maleate (Dimotane) is an antagonist against histamine H1 receptors.</p>Formule :C16H19BrN2·C4H4O4Degré de pureté :99.80%Couleur et forme :Crystal PowderMasse moléculaire :435.31Quinidine hydrochloride monohydrate
CAS :<p>Quinidine hydrochloride monohydrate is an optical isomer of quinine. Quinidine prolongs cellular action potential and decreases automaticity.</p>Formule :C20H27ClN2O3Degré de pureté :94.4% - 99.68%Couleur et forme :SolidMasse moléculaire :378.89ML418
CAS :<p>ML418 is a potent, selective and CNS penetrating Kir7.1 potassium channel blocker (IC50 = 310 nM), and also potently inhibits Kir6.2/SUR1.</p>Formule :C19H24ClN3O3Degré de pureté :99.3%Couleur et forme :SolidMasse moléculaire :377.87Tannic acid
CAS :<p>Tannic acid (Gallotannic acid) is a novel hERG channel blocker.</p>Formule :C76H52O46Degré de pureté :AR - ARCouleur et forme :Light Yellow To Light Brown Solid Solid Particulate/PowderMasse moléculaire :1701.2Doxapram hydrochloride hydrate
CAS :<p>Doxapram hydrochloride hydrate (Doxapram HCl) inhibits TASK-1, TASK-3, TASK-1/TASK-3 heterodimeric channel function with EC50 of 0.41, 37, 9 μM, respectively.</p>Formule :C24H33ClN2O3C24H30N2O2·ClH·H2ODegré de pureté :99.64% - >99.99%Couleur et forme :SolidMasse moléculaire :432.99Butamben
CAS :<p>Butamben (Butyl 4-aminobenzoate) is a long-duration local anesthetic used for the treatment of chronic pain.</p>Formule :C11H15NO2Degré de pureté :99.43%Couleur et forme :Crystals From Alc Physical Description Yellow Powder Insoluble In Water (Ntp 1992)Masse moléculaire :193.24VU591 hydrochloride
CAS :<p>VU591 hydrochloride is a selective Kir1.1 (ROMK) blocker with IC50 of 0.24 μM, not affecting Kir7.1, Kir2.1, Kir2.3, or Kir4.1, similar to VU 590.</p>Formule :C16H13ClN6O5Degré de pureté :98.93% - 99.22%Couleur et forme :SolidMasse moléculaire :404.76Ifenprodil Tartrate
CAS :<p>Ifenprodil is a selective NMDA receptor (glutamate) antagonist.</p>Formule :C21H27NO2C4H6O6Degré de pureté :99.02% - 99.55%Couleur et forme :SolidMasse moléculaire :400.491-EBIO
CAS :<p>1-EBIO (1-EBIO) is a calium channel agonist.</p>Formule :C9H10N2ODegré de pureté :98.75%Couleur et forme :SolidMasse moléculaire :162.19NS3623
CAS :<p>NS3623 is an activator of human ether-a-go-go-related gene potassium channels.</p>Formule :C15H10BrF3N6ODegré de pureté :97.06%Couleur et forme :SolidMasse moléculaire :427.18Tipepidine hydrochloride
CAS :<p>Tipepidine hydrochloride: reversible DA D2 receptor inhibitor, IC50 7.0 μM, with antidepressant effects.</p>Formule :C15H18ClNS2Degré de pureté :99.97%Couleur et forme :SolidMasse moléculaire :311.89Repaglinide
CAS :<p>Repaglinide, a benzoic acid derivative, stimulates insulin, treats type 2 diabetes, and may rarely cause acute liver injury.</p>Formule :C27H36N2O4Degré de pureté :99.73% - >99.99%Couleur et forme :White To Off-White SolidMasse moléculaire :452.59Glipizide
CAS :<p>Glipizide (CP 28720) is a short-acting, second-generation sulfonylurea with hypoglycemic activity.</p>Formule :C21H27N5O4SDegré de pureté :99.67% - 99.75%Couleur et forme :SolidMasse moléculaire :445.54NS13001
CAS :<p>NS13001, an oral SK channel modulator, shows promise for SCA2 therapy; EC50: 1.8 µM (SK2), 0.14 µM (SK3).</p>Formule :C17H16ClN7Degré de pureté :99.55%Couleur et forme :SolidMasse moléculaire :353.81Mefloquine hydrochloride
CAS :<p>Mefloquine hydrochloride (Mefloquin hydrochloride) is a quinoline derivative used for the prevention and therapy of P. falciparum malaria.</p>Formule :C17H17ClF6N2ODegré de pureté :99% - 99.74%Couleur et forme :Off-White To Yellow SolidMasse moléculaire :414.77Dronedarone hydrochloride
CAS :<p>Dronedarone hydrochloride (SR33589) is an amiodarone analog which has an effective and promising treatment for Atrial fibrillation.</p>Formule :C31H44N2O5S·HClDegré de pureté :99.61%Couleur et forme :SolidMasse moléculaire :593.22VU0134992 hydrochloride
CAS :<p>VU0134992 hydrochloride is the first subtype-preferring, orally active and selective blocker of Kir4.1 potassium channel pore(IC50 : 0.97 μM).</p>Formule :C20H32BrClN2O2Degré de pureté :>99.99%Couleur et forme :SolidMasse moléculaire :447.84BMS-394136
CAS :<p>BMS-394136 (BMS 394136) is a KV1.5 antagonist for the treatment of cardiovascular diseases such as arrhythmias and atrial fibrillation.</p>Formule :C24H21Cl2FN4ODegré de pureté :98.19% - 98.67%Couleur et forme :SolidMasse moléculaire :471.35IK1 inhibitor PA-6
CAS :<p>IK1 inhibitor PA-6 (PA-6) is a selective and potent inhibitor of IK1 (KIR2.x ion-channel-carried inward rectifier current)(IC50 of 12-15 nM for human and mouse</p>Formule :C31H32N4O2Degré de pureté :98.9%Couleur et forme :SolidMasse moléculaire :492.61Eleclazine hydrochloride
CAS :<p>Eleclazine hydrochloride (GS 6615 hydrochloride) is a novel inhibitor of late Na+ current (IC50: 0.7 uM).</p>Formule :C21H17ClF3N3O3Degré de pureté :99.86%Couleur et forme :SolidMasse moléculaire :451.83Hydroxyhexamide
CAS :<p>Hydroxyhexamide ((±)-Hydroxyhexamid) is a pharmacologically active metabolite of Acetohexamide, used as a hypoglycemic agent.</p>Formule :C15H22N2O4SDegré de pureté :98.91%Couleur et forme :SolidMasse moléculaire :326.41Ketanserin
CAS :<p>Ketanserin: quinazoline derivative, 5-HT2 receptor antagonist, may lower blood pressure and inhibit blood clots.</p>Formule :C22H22FN3O3Degré de pureté :99.19% - 99.73%Couleur et forme :SolidMasse moléculaire :395.43Ropivacaine
CAS :<p>Ropivacaine (LEA-103 HCl) is a local anaesthetic drug belonging to the amino amide group.</p>Formule :C17H26N2ODegré de pureté :97.75% - >99.99%Couleur et forme :SolidMasse moléculaire :274.40Ropivacaine hydrochloride
CAS :<p>Ropivacaine hydrochloride (Ropivacaine monohydrochloride) is the hydrochloride salt of ropivacaine, a local anesthetic of the amide type with analgesic activity</p>Formule :C17H26N2O·HClDegré de pureté :99.85% - 99.95%Couleur et forme :SolidMasse moléculaire :310.86Quinine
CAS :<p>Quinine is a natural cinchona alkaloid that has been used for centuries in the prevention and therapy of malaria.</p>Formule :C20H24N2O2Degré de pureté :99.93% - 99.97%Couleur et forme :White Solid PowderMasse moléculaire :324.42Oxybutynin
CAS :<p>Oxybutynin (Ditropan) is a synthetic anticholinergic agent that is used for treatment of urinary incontinence and overactive bladder syndrome.</p>Formule :C22H31NO3Degré de pureté :97.81% - 99.57%Couleur et forme :White To Off-White Crystalline PowderMasse moléculaire :357.49Terfenadine
CAS :<p>Terfenadine, metabolized to fexofenadine by CYP3A4, is a non-sedative antihistamine targeting H1 receptors.</p>Formule :C32H41NO2Degré de pureté :98.76% - 99.75%Couleur et forme :SolidMasse moléculaire :471.67Disopyramide
CAS :<p>Disopyramide, or Triombrin, a class I anti-arrhythmic with membrane-stabilizing effects, has heart depressant, anticholinergic, and anesthetic properties.</p>Formule :C21H29N3ODegré de pureté :99.62%Couleur et forme :SolidMasse moléculaire :339.47Glibenclamide
CAS :<p>Glibenclamide (Glyburide) is an antidiabetic sulfonylurea derivative with actions similar to those of chlorpropamide.</p>Formule :C23H28ClN3O5SDegré de pureté :99.05% - 99.75%Couleur et forme :SolidMasse moléculaire :494.00Clofilium tosylate
CAS :<p>Clofilium tosylate is a potassium channel blocker, induces apoptosis on human promyelocytic leukemia (HL-60) cells.</p>Formule :C28H44ClNO3SDegré de pureté :99.68%Couleur et forme :SolidMasse moléculaire :510.17Minoxidil
CAS :<p>Minoxidil (U10858) is an orally administered vasodilator with hair growth stimulatory and antihypertensive effects.</p>Formule :C9H15N5ODegré de pureté :99.885% - >99.99%Couleur et forme :Crystals From Methanol-Acetonitrile SolidMasse moléculaire :209.25DCPIB
CAS :<p>DCPIB, a known specific and potent inhibitor of volume-regulated anion channels (VRAC),DCPIB displayed superior selectivity toward TRESK with an IC50 of 0.14 μM</p>Formule :C22H28Cl2O4Degré de pureté :99.79% - 99.87%Couleur et forme :SolidMasse moléculaire :427.36VU6036720
<p>VU6036720 is a potent and selective inhibitor of the isomeric Kir4.1/5.1.VU6036720 inhibits Kir4.1/5.1 activity by decreasing the channel open-circuit</p>Formule :C20H22ClFN4O2SDegré de pureté :98.1%Couleur et forme :SoildMasse moléculaire :436.93Linoleoyl glycine
CAS :<p>Linoleoyl glycine activates hKCNQ1/hKCNE1 channels, has analgesic properties, and is found in skin, spinal cord, and brain.</p>Formule :C20H35NO3Degré de pureté :98.96%Couleur et forme :SolidMasse moléculaire :337.5AZD 7009
CAS :<p>AZD 7009 is a novel antiarrhythmic compound that inhibits the sodium current of hNav1.5 in CHO K1 cells with an IC50 of 11 uM.</p>Formule :C23H34N4O5Degré de pureté :98.42% - 98.51%Couleur et forme :SoildMasse moléculaire :446.544-Aminopyridine
CAS :<p>4-Aminopyridine (Dalfampridine) is a nonselective potassium (K+) channel blocker that binds to the cytoplasmic side of the cell membrane.</p>Formule :C5H6N2Degré de pureté :91.61%Couleur et forme :SolidMasse moléculaire :94.11Miconazole
CAS :<p>Miconazole (R18134) is an imidazole antifungal agent that is used topically and by intravenous infusion.</p>Formule :C18H14Cl4N2ODegré de pureté :98% - >99.99%Couleur et forme :SolidMasse moléculaire :416.13Amiodarone hydrochloride
CAS :<p>Amiodarone HCl: Antianginal, class III antiarrhythmic. Lengthens heart muscle action, slows heart rate, reduces vascular resistance.</p>Formule :C25H29I2NO3·HClDegré de pureté :99.82% - ≥95%Couleur et forme :White To Cream Crystalline PowderMasse moléculaire :681.78
