Canal potassique
Les canaux potassiques sont un groupe diversifié de protéines membranaires qui facilitent le flux des ions potassium (K+) à travers la membrane cellulaire. Ces canaux jouent un rôle crucial dans le maintien du potentiel de membrane au repos, la régulation du volume cellulaire et le contrôle de l'excitabilité des neurones et des cellules musculaires. Les canaux potassiques sont impliqués dans divers processus physiologiques, y compris la régulation du rythme cardiaque, la sécrétion d'insuline et la libération de neurotransmetteurs. La dysrégulation des canaux potassiques est liée à des conditions telles que les arythmies, l'épilepsie et l'hypertension. Chez CymitQuimica, nous proposons une large gamme de modulateurs de canaux potassiques pour soutenir vos recherches en électrophysiologie, santé cardiovasculaire et neurobiologie.
304 produits trouvés pour "Canal potassique"
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Tetrandrine
CAS :Tetrandrine (Sinomenine A) is a naturally occurring biphenylisoquinoline alkaloid, a calcium channel inhibitor. Cost-effective and quality-assured.Formule :C38H42N2O6Degré de pureté :99.61% - 99.94%Couleur et forme :White SolidMasse moléculaire :622.75NS 11021
CAS :NS 11021 (NS11021) , a novel opener of large-conductance Ca(2+)-activated K(+) channelsFormule :C16H9BrF6N6SDegré de pureté :97.26%Couleur et forme :SolidMasse moléculaire :511.24Ref: TM-T4294
1mg42,00€5mg88,00€10mg128,00€25mg263,00€50mg447,00€100mg760,00€200mg1.018,00€1mL*10mM (DMSO)89,00€Tetraethylammonium bromide
CAS :Tetraethylammonium bromide (TEA bromide) can selectively block potassium channels.
Formule :C8H20BrNDegré de pureté :98%Couleur et forme :White SolidMasse moléculaire :210.16Tetraethylammonium chloride
CAS :Tetraethylammonium chloride is a quaternary ammonium compound.Formule :C8H20ClNDegré de pureté :≥95%Couleur et forme :White Solid Solid Particulate/PowderMasse moléculaire :165.7ML133 hydrochloride
CAS :ML133 hydrochloride (ML133 HCl) is a selective potassium channel inhibitor for Kir2.1, has no effect on Kir1.1 and weak activity for Kir4.1 and Kir7.1.Formule :C19H19NO·HClDegré de pureté :99.48%Couleur et forme :SolidMasse moléculaire :313.82Ref: TM-T6592
5mg48,00€10mg63,00€25mg101,00€50mg161,00€100mg259,00€200mg335,00€500mg567,00€1mL*10mM (DMSO)50,00€KCNQ2/3 activator-1
CAS :KCNQ2/3 activator-1 is a Kv7.2/Kv7.3 (KCNQ2/3) potassium channel activator.Formule :C23H29FN2ODegré de pureté :99.16% - 99.47%Couleur et forme :SolidMasse moléculaire :368.49Ref: TM-T9400
2mg38,00€5mg58,00€10mg89,00€25mg144,00€50mg224,00€100mg353,00€500mg888,00€1mL*10mM (DMSO)64,00€RY785
CAS :RY785 is a potent and selective inhibitor of voltage-gated potassium channel such as KV2.2 (IC50 = 50 nM). RY785 may be used in pain relief studies.Formule :C21H20N4O2SDegré de pureté :99.78%Couleur et forme :SolidMasse moléculaire :392.47Ref: TM-T12786
1mg49,00€5mg137,00€10mg222,00€25mg378,00€50mg530,00€100mg745,00€200mg1.035,00€1mL*10mM (DMSO)118,00€SKF-96365 hydrochloride
CAS :SKF-96365 hydrochloride (SKF96365) , a SOCE inhibitor, exhibits potent anti-neoplastic activity by inducing cell-cycle arrest and apoptosis in colorectal YFormule :C22H27ClN2O3Degré de pureté :99.47% - 99.92%Couleur et forme :SolidMasse moléculaire :402.91Ref: TM-T2170
5mg54,00€10mg81,00€25mg131,00€50mg230,00€100mg445,00€200mg680,00€500mg1.054,00€1mL*10mM (DMSO)59,00€CLP290
CAS :CLP290 is an activator of the neuron-specific K+-Cl cotransporter KCC2 and displays potential for the treatment of a wide range of neurological and psychiatricFormule :C19H21FN4O3SDegré de pureté :99.93% - >99.99%Couleur et forme :SolidMasse moléculaire :404.46Ref: TM-T5444
1mg34,00€5mg73,00€10mg116,00€25mg190,00€50mg286,00€100mg430,00€200mg628,00€1mL*10mM (DMSO)62,00€Oxypeucedanin
CAS :1.Formule :C16H14O5Degré de pureté :98.66% - 98.85%Couleur et forme :SolidMasse moléculaire :286.28Guanosine 5'-diphosphate
CAS :Guanosine 5'-diphosphate (GDP) as Potential Iron Mobilizer, Preventing the Hepcidin-Ferroportin Interaction and Modulating the Interleukin-6/Stat-3 Pathway.Formule :C10H15N5O11P2Degré de pureté :98.46% - 99.52%Couleur et forme :SolidMasse moléculaire :443.2VU0134992
CAS :VU0134992 is an Kir4.1 blocker with an IC50 value of 0.97 μMFormule :C20H31BrN2O2Degré de pureté :99.86%Couleur et forme :SolidMasse moléculaire :411.38XE 991 dihydrochloride
CAS :XE 991 dihydrochloride is a Kv7 (KCNQ) channel blocker.Formule :C26H22Cl2N2ODegré de pureté :98.68%Couleur et forme :SolidMasse moléculaire :449.37BMS-191011
CAS :BMS-191011 (BMS-A) is an activator of large-conductance calcium-activated potassium (BKCa) channels ,effective in stroke modelsFormule :C16H10ClF3N2O3Degré de pureté :97.43%Couleur et forme :SolidMasse moléculaire :370.71Guanosine 5'-diphosphate disodium salt
CAS :5'-GDP-Na2: a nucleoside diphosphate, iron mobilizer, blocks hepcidin-ferroportin, affects IL-6/stat-3.
Formule :C10H13N5Na2O11P2Degré de pureté :99.40%Couleur et forme :White PowderMasse moléculaire :487.16ML 297
CAS :ML 297 is a selective Kir3.1/3.2 (GIRK1/2) channel activator (IC50 values are 160, 887 and 914 nM for GIRK1/2, GIRK1/4 and GIRK1/3 respectively).Formule :C17H14F2N4ODegré de pureté :97.85%Couleur et forme :SolidMasse moléculaire :328.32NS1643
CAS :NS1643 is a potent human ether-a-go-go related gene (hERG) KV11.1 channel activator with EC50 of 10.5 μM.Formule :C15H10F6N2O3Degré de pureté :98.37% - 99.31%Couleur et forme :SolidMasse moléculaire :380.24GAL-021
CAS :GAL-021 an intravenous BKCa-channel blocker.Formule :C11H22N6ODegré de pureté :97.71% - 99.66%Couleur et forme :SolidMasse moléculaire :254.33Ref: TM-T3557
1mg34,00€5mg71,00€10mg98,00€25mg177,00€50mg268,00€100mg414,00€500mg888,00€1mL*10mM (DMSO)80,00€Daurisoline
CAS :Daurisoline ((R,R)-Daurisoline) is a hERG inhibitor. Daurisoline is also an autophagy blocker.Formule :C37H42N2O6Degré de pureté :98% - 99.96%Couleur et forme :Light Yellow PowderMasse moléculaire :610.74Talatisamine
CAS :Talatisamine and TEA mitigate Aβ oligomer effects on I(K), bolstering cell survival and reducing K(+) loss-induced apoptosis; promising for further study.Formule :C24H39NO5Degré de pureté :98.62% - 99.44%Couleur et forme :SolidMasse moléculaire :421.57NS-1619
CAS :NS1619 have cardio-protective effects after ischemia-reperfusion injury.Formule :C15H8F6N2O2Degré de pureté :97.66% - 98%Couleur et forme :SolidMasse moléculaire :362.23Quinidine
CAS :Quinidine is a stereoisomer of the antimalarial agent quinine and a class Ia antiarrhythmic agent. for the treatment of abnormal heart rhythms and also malaria.Formule :C20H24N2O2Degré de pureté :97.03% - 99.99%Couleur et forme :Crystals With 2 5 Mol Water Of Crystallization; Crystals From Dilute Alcohol Physical Description Crystals Or White Powder (Ntp 1992)Masse moléculaire :324.42Ibutilide Fumarate
CAS :Ibutilide Fumarate is a class III antiarrhythmic, prolonging action potentials by enhancing sodium influx, and can extend QT interval.Formule :(C20H36N2O3S)2·C4H4O4Degré de pureté :99.68% - 99.74%Couleur et forme :SolidMasse moléculaire :885.23GW9508
CAS :GW9508(GW 9508) is a potent and selective agonist for FFA1 (GPR40), stimulates insulin secretion in a glucose-sensitive manner.
Formule :C22H21NO3Degré de pureté :97.89% - 99.19%Couleur et forme :SolidMasse moléculaire :347.41JNJ 303
CAS :JNJ 303 is a potent blocker of IKs (IC50 : 64 nM).Formule :C21H29ClN2O4SDegré de pureté :99.28%Couleur et forme :SolidMasse moléculaire :440.98Ref: TM-T7653
1mg46,00€2mg62,00€5mg94,00€10mg140,00€25mg309,00€50mg447,00€100mg667,00€1mL*10mM (DMSO)96,00€TRAM-34
CAS :TRAM-34 (Triarylmethane-34), an effective and specific inhibitor of the intermediate-conductance Ca2+-activated K+ channel, does not block cytochrome P450.
Formule :C22H17ClN2Degré de pureté :99.01% - 99.91%Couleur et forme :SolidMasse moléculaire :344.84ML335
CAS :ML335 is a selective activator of TREK-1 and TREK-2.Formule :C15H14Cl2N2O3SDegré de pureté :99.73% - 99.79%Couleur et forme :SolidMasse moléculaire :373.25Ref: TM-T4224
2mg40,00€5mg59,00€10mg89,00€25mg177,00€50mg268,00€100mg401,00€200mg580,00€1mL*10mM (DMSO)59,00€BAPTA-AM
CAS :BAPTA-AM is a calcium chelator that is cell-permeable and selective, blocking hERG, hKv1.3, and hKv1.5 channels (IC50=1.3/1.45/1.23 μM).Formule :C34H40N2O18Degré de pureté :98% - 99.47%Couleur et forme :White Powder Or Crystalline PowderMasse moléculaire :764.68NS309
CAS :NS309 activates SK/KCa2, IK/KCa3.1 (0.12-1.2 μM EC50, 10-90 nM EC50), and Kv11.1 channels; doesn't affect BK/KCa1.1; modulates neuronal firing.Formule :C8H4Cl2N2O2Degré de pureté :97.55%Couleur et forme :SolidMasse moléculaire :231.04Ref: TM-T4612
5mg54,00€10mg65,00€25mg113,00€50mg205,00€100mg305,00€200mg445,00€500mg712,00€1mL*10mM (DMSO)59,00€ICA 110381
CAS :ICA 110381 is a KCNQ2/Q3 potassium channel opener for the treatment of epilepsyFormule :C12H8Cl2N2ODegré de pureté :97.72%Couleur et forme :SolidMasse moléculaire :267.11Flecainide hydrochloride
CAS :Flecainide is a medication used to prevent and treat abnormally fast heart rates. This includes ventricular and supraventricular tachycardias.Formule :C17H21ClF6N2O3Degré de pureté :97.79%Couleur et forme :SolidMasse moléculaire :450.81ICA-069673
CAS :ICA-069673 is an activator of KCNQ2/Q3 potassium channel (IC50: 0.69 μM).Formule :C11H6ClF2N3ODegré de pureté :99.04% - 99.68%Couleur et forme :SolidMasse moléculaire :269.63TKIM
CAS :TKIM is a TWIK-related potassium channel 1 (TREK-1) inhibitor, binding to the pocket of the intermediate (IM) state of TREK-1.Formule :C18H14ClN3O2SDegré de pureté :99.47%Couleur et forme :SolidMasse moléculaire :371.84Ref: TM-T8700
1mg39,00€5mg89,00€10mg124,00€25mg212,00€50mg298,00€100mg399,00€200mg537,00€1mL*10mM (DMSO)96,00€Amifampridine
CAS :Amifampridine blocks nerve potassium channels, extends action potentials, boosts acetylcholine release, and treats rare muscle diseases.Formule :C5H7N3Degré de pureté :99.82%Couleur et forme :Slightly Beige PowderMasse moléculaire :109.13APD668
CAS :APD668 is a potent GPR119 agonist with EC50 of 2.7 nM and 33 nM for hGPR119 and ratGPR119, respectively.Formule :C21H24FN5O5SDegré de pureté :99.74% - 99.97%Couleur et forme :SolidMasse moléculaire :477.51ML277
CAS :ML277 (CID-53347902) was identified as a potent activator of KCNQ1 channels (EC(50)=260 nM).Formule :C23H25N3O4S2Degré de pureté :99.35%Couleur et forme :SolidMasse moléculaire :471.59Quinidine sulfate dihydrate
CAS :Quinidine sulfate dihydrate (Pitayine Sodium) is a potent and selective cytochrome P450db inhibitorFormule :C40H54N4O10SDegré de pureté :99.85%Couleur et forme :White To Light Yellow Crystal PowdeMasse moléculaire :782.9Ref: TM-T8125
5mg42,00€10mg52,00€25mg73,00€50mg94,00€100mg142,00€200mg207,00€500mg348,00€1mL*10mM (DMSO)62,00€Cholesterol myristate
CAS :Cholesterol myristate, a natural steroid in Chinese medicine, affects GABAA, nicotinic receptors, and potassium channels.
Formule :C41H72O2Degré de pureté :99.65%Couleur et forme :SolidMasse moléculaire :597.01Dofetilide
CAS :Dofetilide (UK 68789), a class III antiarrhythmic sulfonamide, blocks Ikr cardiac channels, prolongs action potential, and treats atrial fibrillation/flutter.Formule :C19H27N3O5S2Degré de pureté :97.85% - 99.06%Couleur et forme :Off-White Or Yellowish Crystalline PowderMasse moléculaire :441.56Ref: TM-T6476
2mg34,00€5mg50,00€10mg65,00€25mg108,00€50mg167,00€100mg234,00€200mg348,00€1mL*10mM (DMSO)52,00€Minoxidil sulfate
CAS :Minoxidil sulfate (U-58838) is the active metabolite required to exert the vasodilatory and hair growing effects of minoxidil.Formule :C9H15N5O4SDegré de pureté :99.01% - 99.72%Couleur et forme :White Crystalline SolidMasse moléculaire :289.31ASP2905
CAS :ASP-2905 is a potent and selective inhibitor of potassium channel Kv12.2 encoded by the Kcnh3/BEC1 gene.Formule :C20H17FN8Degré de pureté :97.29% - 99.78%Couleur et forme :SolidMasse moléculaire :388.4Ref: TM-T9070
1mg34,00€2mg46,00€5mg66,00€10mg90,00€25mg178,00€50mg295,00€100mg485,00€1mL*10mM (DMSO)73,00€AM-92016 hydrochloride
CAS :AM-92016 is a specific blocker of rectifier potassium current.Formule :C19H24Cl2N2O4S·HClDegré de pureté :98.68%Couleur et forme :SolidMasse moléculaire :483.84Ref: TM-T5585
2mg34,00€5mg50,00€10mg92,00€25mg156,00€50mg264,00€100mg378,00€200mg537,00€1mL*10mM (DMSO)55,00€AUT1
CAS :AUT1 (AUT-1) is a novel specific modulator of Kv3 channels (EC50: 4.7 and 4.9 uM for Kv3.1b and Kv3.2a).Formule :C18H19N3O4Degré de pureté :99.8% - 99.95%Couleur et forme :SolidMasse moléculaire :341.36Ref: TM-T5183
1mg34,00€2mg47,00€5mg71,00€10mg101,00€25mg177,00€50mg264,00€100mg404,00€200mg583,00€1mL*10mM (DMSO)79,00€Iptakalim Hydrochloride
CAS :Iptakalim, a lipophilic para-amino compound, is a novel ATP-sensitive potassium channel (KATP) opener, as well as an α4β2-containing nicotinic acetylcholineFormule :C9H22ClNDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :179.731GSK369796 Dihydrochloride
CAS :GSK369796 Dihydrochloride (N-tert-butylisoquine),is an anti-malaria drug candidate.Formule :C20H24Cl3N3ODegré de pureté :>99.99%Couleur et forme :SolidMasse moléculaire :428.78Ref: TM-T7195
1mg74,00€2mg96,00€5mg141,00€10mg185,00€25mg353,00€50mg532,00€100mg760,00€1mL*10mM (DMSO)138,00€Sematilide hydrochloride
CAS :Sematilide hydrochloride (CK-1752) is a class III antiarrhythmic. It is a selectively delayed rectifier K+ current (IKr) channel blocker.Formule :C14H24ClN3O3SDegré de pureté :99.14%Couleur et forme :SolidMasse moléculaire :349.87Ropivacaine hydrochloride monohydrate
CAS :Ropivacaine hydrochloride monohydrate (LEA-103 HCl) is an anaesthetic agent and blocks impulse conduction through inhibiting sodium ion influx reversibly.Formule :C17H29ClN2O2Degré de pureté :99.94% - 99.95%Couleur et forme :White SolidMasse moléculaire :328.882,2,2-Trichloroethanol
CAS :2,2,2-Trichloroethanol is an agonist of the nonclassical K2P channels TREK-1 and TRAAK.Formule :C2H3Cl3ODegré de pureté :99.74%Couleur et forme :LiquidMasse moléculaire :149.4PAP-1
CAS :PAP-1 (5-(4-Phenoxybutoxy)psoralen) is a selective, and orally active Kv1.3 blocker (EC50: 2 nM).Formule :C21H18O5Degré de pureté :99.35% - 99.75%Couleur et forme :White SolidMasse moléculaire :350.36Ref: TM-TQ0179
2mg63,00€5mg88,00€10mg136,00€25mg291,00€50mg520,00€100mg550,00€200mg785,00€1mL*10mM (DMSO)90,00€Quinine dihydrochloride
CAS :Quinine dihydrochloride (Quinine bimuriate) is a primary alkaloid of various species of Cinchona (Rubiaceae).Formule :C20H26Cl2N2O2Degré de pureté :99.79% - 99.97%Couleur et forme :White SolidMasse moléculaire :397.34
