Récepteur CGRP
Les récepteurs du CGRP sont impliqués dans la transmission de la douleur et la régulation du flux sanguin. Le CGRP est un neuropeptide qui joue un rôle crucial dans la physiopathologie de la migraine en dilatant les vaisseaux sanguins et en modulant les voies de signalisation de la douleur. Cibler les récepteurs du CGRP est devenu une approche prometteuse dans le développement de thérapies contre la migraine. Chez CymitQuimica, nous proposons une gamme de modulateurs des récepteurs du CGRP pour soutenir vos recherches sur la gestion de la douleur, la neurobiologie et la santé vasculaire.
56 produits trouvés pour "Récepteur CGRP".
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Erenumab
CAS :Erenumab: human antibody blocking CGRP receptors to prevent migraines.Degré de pureté :99.43% (SEC-HPLC) - > 95%Couleur et forme :LiquidMasse moléculaire :146.2 kDaPHM-27 (human) acetate
PHM-27 (human) acetate is the endogenous peptide product of prepro-VIP (human), an agonist of the calcitonin receptor (EC 50 = 11 nM). enhanced insulin secretion.Formule :C137H215F3N34O42SDegré de pureté :99.20%Couleur et forme :SolidMasse moléculaire :3099.44Calcitonin (human) acetate
CAS :Calcitonin (human) acetate (21215-62-3, free base) is a synthetic polypeptide hormone composed of 32 amino acids.Formule :C153H230N40O47S3Degré de pureté :99.46%Couleur et forme :White SolidMasse moléculaire :3477.91Vazegepant
CAS :Vazegepant is an intranasal CGRP receptor antagonist utilized for conducting acute migraine research.Formule :C36H46N8O3Degré de pureté :98.61% - 99.98%Couleur et forme :White SolidMasse moléculaire :638.80Ref: TM-T38734
1mg90,00€5mg215,00€1mL*10mM (DMSO)289,00€10mg318,00€25mg537,00€50mg767,00€100mg1.054,00€MK-3207
CAS :MK-3207 is a potent, oral CGRP receptor antagonist with high selectivity for human and monkey receptors, inhibiting blood flow in vivo.Formule :C31H29F2N5O3Couleur et forme :White SolidMasse moléculaire :557.59α-CGRP, rat
CAS :Endogenous neuropeptide, potent vasodilatorFormule :C162H262N50O52S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :3806.25β-CGRP, human
CAS :β-CGRP, human ,a 37-amino acid peptide,is the beta form of Calcitonin-gene-related peptide (β-CGRP), involved extensively in regulation of the cardiovascularFormule :C162H267N51O48S3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :3793.41(3R,5R,6S)-Atogepant
(3R,5R,6S)-Atogepant (MK-8031) is a CGRP antagonist enantiomer used in migraine research.Formule :C29H23F6N5O3Couleur et forme :SolidMasse moléculaire :603.52PHM-27 (human)
CAS :Human-derived peptide, VIP/PHM 27 analog, boosts insulin by targeting calcitonin receptor with an EC50 of 11 nM.Formule :C135H214N34O40SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :2985.44Adrenomedullin (AM) (22-52), human TFA
Adrenomedullin (AM) human (22-52) is a truncated NH2 TFA-modified adrenal medullary receptor antagonist.Formule :C161H253N46F3O50Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :3690.06Calcitonin Gene Related Peptide (CGRP) II, rat
CAS :CGRP II is a potent vasodilator that boosts pancreatic enzyme levels by activating β-cell receptors.Formule :C163H267N51O50S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :3805.31Adrenomedullin (11-50), rat
CAS :Adrenomedullin 11-50 rat is a peptide, stimulates CGRP1 receptor for vasodilation, used in bone growth research.Formule :C194H304N58O59S4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :4521.17HTL22562
CAS :HTL22562 is a calcitonin gene-related peptide (CGRP) receptor antagonist for acute treatment of migraine.Formule :C40H49N11O5Couleur et forme :SolidMasse moléculaire :763.904α-CGRP(human)
CAS :Endogenous calcitonin gene-related peptide receptor (CGRP) agonist.Formule :C163H267N51O49S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :3789.33Adrenomedullin (16-31), human
CAS :Adrenomedullin (16-31), human is amino acid residues 16-31 fragment of human adrenomedullin (hADM).Formule :C82H129N25O21S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1865.19α-CGRP(human) TFA
α-CGRP(human) TFA is a 37-amino acid regulatory neuropeptide that is extensively located within the central and peripheral nervous system, functioning as aFormule :C165H268F3N51O51S2Couleur et forme :SolidMasse moléculaire :3903.33Adrenomedullin (16-31), human TFA
Human adrenomedullin (16-31) TFA, fragment 16-31, binds CGRP1 receptor, raises rat blood pressure, not cats’.Formule :C84H130F3N25O23S2Couleur et forme :SolidMasse moléculaire :1979.21Adrenotensin (human)
CAS :Adrenotensin: human 153-185 fragment of Adrenomedullin precursor, a 52-amino acid peptide in CGRP hormone family.Formule :C143H224N42O43Couleur et forme :SolidMasse moléculaire :3219.56Calcitonin Gene Related Peptide (CGRP) II, rat TFA
Rat CGRP II TFA: potent vasodilator and CGRP receptor activator for cardiovascular research.Formule :C165H268F3N51O52S2Couleur et forme :SolidMasse moléculaire :3919.33Olcegepant hydrochloride
CAS :Olcegepant hydrochloride (BIBN-4096 hydrochloride) is a selective calcitonin gene-related peptide 1 (CGRP1) receptor antagonist.Formule :C38H48Br2ClN9O5Degré de pureté :99.69%Couleur et forme :SolidMasse moléculaire :906.11CRSP-1
CAS :Central CT receptor agonist, 350x stronger than CT, no CGRP or adrenomedullin action, inhibits osteoclasts, affects rat feeding, body temp, and calcium.Formule :C175H294N54O49S5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :4098.88Cagrilintide acetate
.Cagrilintide is a long-acting amylin analog,treat diabetes and obesity by reducing appetite through activation of the AMY3R and calcitonin receptor.Formule :C196H316N54O61S2Degré de pureté :99.88%Couleur et forme :White SolidMasse moléculaire :4469.06β-CGRP (mouse)
β-CGRP (mouse), a calcitonin gene-related peptide, induces vasodilation and is applicable in research areas including cardiovascular, pro-inflammatory, migraine, and metabolic studies.Formule :C165H265N49O55S2Couleur et forme :SolidMasse moléculaire :3879.29CGRP 8-37 (rat)
CAS :CGRP 8-37 (rat) is a CGRP receptor antagonist, a CGRP fragment with potential anti-injury effects that induces arterial relaxation.Formule :C138H224N42O41Degré de pureté :99.28%Couleur et forme :SolidMasse moléculaire :3127.51Adrenomedullin (AM) (22-52), human acetate
Adrenomedullin (AM) (22-52), human acetate is an antagonist of calcitonin generelated peptide receptor in the hindlimb vascular bed of the cat and anFormule :C161H256N46O50Degré de pureté :99.42%Couleur et forme :SolidMasse moléculaire :3636.09α-CGRP (mouse, rat) TFA
α-CGRP (mouse, rat) TFA, a neuropeptide belonging to the calcitonin gene-related peptide (CGRP) family, is predominantly located at neuromuscular junctions andFormule :C162H262N50O52S2·C2HF3O2Degré de pureté :98%Couleur et forme :SolidGalcanezumab
CAS :Galcanezumab: humanized IgG4 antibody that targets CGRP for migraine and cluster headache prevention/treatment.Degré de pureté :> 95%Couleur et forme :LiquidMasse moléculaire :144.08 kDaUbrogepant-D5
Ubrogepant-D5 is the deuterium-labeled version of Ubrogepant. It is an orally active and selective antagonist of the calcitonin gene-related peptide receptor (CGRP). Ubrogepant (T17194) exhibits high affinity for CGRP receptors in humans and rhesus monkeys, effectively blocking the cAMP response induced by α-CGRP stimulation. This compound is utilized in studies focused on acute migraine.Couleur et forme :Odour SolidCGRP antagonist 6
CGRP Antagonist 6 (Compound 23) is a potent CGRP receptor antagonist (Ki: 0.84 nM). It is utilized in the study of migraines.Couleur et forme :Odour SolidAdrenomedullin (1-50), rat
CAS :Rat adrenomedullin (1-50) is a 50-AA peptide; induces arterial vasodilation by activating CGRP1 receptors.Formule :C248H381N77O75S5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :5729.5Adrenomedullin (AM) (22-52), human
CAS :Adrenomedullin (ADM) is a 52-aa hypotensive peptide. Adrenomedullin (ADM) has structural similarity with amylin.Formule :C159H252N46O48Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :3576.04HCGRP-(8-37)
CAS :Rat CGRP-(8-37) (VTHRLAGLLSRSGGVVKDNFVPTNVGSEAF) is a highly selective CGRP receptor antagonistFormule :C139H230N44O38Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :3125.59Calcitonin (human)
CAS :Endogenous calcitonin receptor agonist. Lowers systemic blood calcium levels and inhibits bone resorption.Formule :C151H226N40O45S3Degré de pureté :98%Couleur et forme :White Lyophilized PowderMasse moléculaire :3417.87SUN B8155
CAS :SUN B8155 is a CT receptor agonist that induces cAMP formation in cells expressing recombinant human CT receptor.Formule :C14H15N3O3Degré de pureté :99.38% - 99.99%Couleur et forme :Yellow SolidMasse moléculaire :273.29Telcagepant
CAS :Telcagepant (MK-0974) is an oral calcitonin gene-related peptide receptor (CGRP) antagonist that blocks CGRP receptors, migraines and for pain relief.Formule :C26H27F5N6O3Degré de pureté :98.98% - 98.98%Couleur et forme :SolidMasse moléculaire :566.52Calcitonin (salmon)
CAS :Calcitonin (salmon), a calcium regulating hormone, is used to treat osteoporosis in women who are at least 5 years past menopause.Formule :C145H240N44O48S2Degré de pureté :99.41% - 99.80%Couleur et forme :SolidMasse moléculaire :3431.85Olcegepant
CAS :Olcegepant (BIBN-4096) is an effective and selective non-peptide calcitonin gene-related peptide 1 (CGRP1) receptor antagonist (IC50 of 0.03 nM and Ki of 14.4Formule :C38H47Br2N9O5Degré de pureté :96.08% - 97.24%Couleur et forme :SolidMasse moléculaire :869.65Calcitonin(salmon) Acetate(47931-85-1(free base))
Calcitonin(salmon)Acetate(47931-85-1(free base))(Salmon calcitonin) , a calcium regulating hormone, is used to treat osteoporosis in women who are at least 5Formule :C147H243N44O50S2Degré de pureté :99.29% - 99.63%Couleur et forme :White SolidMasse moléculaire :3490.94Vazegepant hydrochloride
CAS :Vazegepant hydrochloride (Vazegepant HCl) is the first intranasal gepant for the acute treatment of migraine and has announced a positive phase II/III study.Formule :C36H47ClN8O3Degré de pureté :98.93%Couleur et forme :White SolidMasse moléculaire :675.3Ref: TM-T8682
1mg102,00€5mg215,00€1mL*10mM (DMSO)313,00€10mg316,00€25mg535,00€50mg763,00€100mg1.054,00€BCTC
CAS :BCTC is a potent TRPV1 antagonist that inhibits capsaicin-induced and acid-induced activation of rat TRPV1 (IC50 of 35 and 6 nM, respectively)Formule :C20H25ClN4ODegré de pureté :99.21% - 99.74%Couleur et forme :White SolidMasse moléculaire :372.89HCGRP-(8-37) acetate
HCGRP-(8-37) acetate is a human calcitonin gene-related peptide (hCGRP) fragment acetate and also an antagonist of CGRP receptor.Formule :C141H234N44O40Degré de pureté :99.53%Couleur et forme :SolidMasse moléculaire :3185.64β-CGRP, human acetate
β-CGRP, human acetate is one of calcitonin peptides and acts via the complex of receptor-activity-modifying protein (RAMP) and calcitonin-receptor-like receptorFormule :C164H271N51O50S3Degré de pureté :99.35%Couleur et forme :SolidMasse moléculaire :3853.46Rimegepant
CAS :View and buy Rimegepant from TargetMol.BMS-927711 is a highly potent, oral calcitonin gene-related peptide (CGRP) receptor antagonist with a Ki value of 0.027 nM.Cited in 1 publications.Formule :C28H28F2N6O3Degré de pureté :99.1% - 99.99%Couleur et forme :White SolidMasse moléculaire :534.56Ref: TM-T4610
1mg52,00€5mg92,00€1mL*10mM (DMSO)105,00€10mg135,00€25mg217,00€50mg318,00€100mg472,00€200mg677,00€Atogepant
CAS :Atogepant (MK-8031) is an orally available, selective and potent calcitonin gene-related peptide receptor (CGRP) antagonist for the study of migraine.Formule :C29H23F6N5O3Degré de pureté :99.66%Couleur et forme :SolidMasse moléculaire :603.52Ref: TM-T26682
1mg147,00€5mg250,00€10mg313,00€1mL*10mM (DMSO)334,00€25mg620,00€50mg1.108,00€100mg1.611,00€200mg2.178,00€Eptinezumab
CAS :Eptinezumab is a humanised monoclonal antibody targeting CGRP (calcitonin gene-related peptide), which prevents CGRP binding to its receptor, migraine.Degré de pureté :95% - 96.9% (SDS-PAGE); 99.8% (SEC-HPLC)Couleur et forme :LiquidMasse moléculaire :143.27 kDaFremanezumab
CAS :Fremanezumab (TEV-48125) is a humanised monoclonal antibody targeting CGRP, capable of neutralising human, mouse and rat CGRP, migraine.Degré de pureté :95% - 97.6% (SDS-PAGE); 95.9% (SEC-HPLC)Couleur et forme :LiquidMasse moléculaire :145.49 kDaSB 268262
CAS :CGRP1 antagonistFormule :C18H15N3O4S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :401.46CGRP antagonist 1
CAS :CGRP antagonist 1 is a potent CGRP receptor antagonist with Ki values of 35 nM and IC50 values of 57 nM, respectively.CGRP antagonist 1 can be used for theFormule :C29H26N4O4Degré de pureté :99.55%Couleur et forme :SolidMasse moléculaire :494.54Ubrogepant
CAS :Ubrogepant (MK-1602) is an antagonist of calcitonin gene-related peptide receptor that can be used in the acute treatment of migraine studies.Formule :C29H26F3N5O3Degré de pureté :99.45% - 99.78%Couleur et forme :Yellow SolidMasse moléculaire :549.54Ref: TM-T17194
1mg144,00€5mg358,00€1mL*10mM (DMSO)432,00€10mg565,00€25mg880,00€50mg1.161,00€100mg1.594,00€MK-8825
CAS :MK-8825 is a CGRP receptor antagonist.Formule :C31H30F2N6O3Couleur et forme :SolidMasse moléculaire :572.61
