Transporteur de monoamine
Les transporteurs de monoamines sont un groupe de protéines membranaires responsables de la recapture des monoamines—telles que la sérotonine, la dopamine et la noradrénaline—depuis la fente synaptique vers les neurones présynaptiques. Ce processus est crucial pour réguler les niveaux de neurotransmetteurs et maintenir une neurotransmission appropriée. La dysrégulation des transporteurs de monoamines est associée à divers troubles psychiatriques et neurologiques, notamment la dépression, l'anxiété et la maladie de Parkinson. Chez CymitQuimica, nous proposons une gamme de modulateurs de transporteurs de monoamines pour soutenir vos recherches en neurobiologie, santé mentale et pharmacologie.
30 produits trouvés pour "Transporteur de monoamine"
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Tetrabenazine
CAS :Tetrabenazine (Ro 1-9569) is a drug formerly used as an antipsychotic and treatment of various movement disorders.Formule :C19H27NO3Degré de pureté :98% - 99.91%Couleur et forme :White To Off-White White To Off-White SolidMasse moléculaire :317.42Reserpine
CAS :<p>Reserpine, an alkaloid from Rauwolfia roots, depletes neurotransmitters, used in treating hypertension and psychosis, but side effects restrict use.</p>Formule :C33H40N2O9Degré de pureté :98.85% - 99.81%Couleur et forme :White Or Pale Buff To Slightly Yellowish Powder With A Bitter Taste (Ntp 1992)Masse moléculaire :608.68FFN 511
CAS :Fluorescent false neurotransmitter (FFN)Formule :C17H20N2O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :284.35FFN 206 dihydrochloride
CAS :<p>FFN 206 dihydrochloride: fluorescent VMAT2 marker, detects subcellular sites, non-inhibitory to DAT.</p>Formule :C12H15ClN2O2Degré de pureté :98.96% - >99.99%Couleur et forme :SolidMasse moléculaire :254.71VMAT2-IN-3
VMAT2-IN-3 (compound 10) is a potent inhibitor of vesicular monoamine transporter 2 (VMAT2), with a Ki value of 0.71 nM, showing promise for research in neurological or psychiatric disorders.Formule :C22H35NO4Masse moléculaire :377.25661GZ-793A
CAS :GZ-793A suppresses dopamine uptake at the vesicular monoamine transporter-2 (VMAT2. A lobelane analog, GZ-793A interacts with the vesicular monoamine transporter-2 to inhibit the effect of methamphetamine.Formule :C26H38ClNO4Masse moléculaire :464.043,4-Dihydroxypyrovalerone HCl
CAS :3,4-Dihydroxypyrovalerone HCl is an analog of Pyrovalerone. Pyrovalerone inhibits the dopamine transporter (DAT), serotonin transporter (SERT), and norepinephrine transporter (NET).Formule :C15H22ClNO3Couleur et forme :SolidMasse moléculaire :299.79LY-368975 hydrochloride
CAS :<p>LY-368975 hydrochloride is a bioactive chemical.</p>Formule :C17H22ClNOSCouleur et forme :SolidMasse moléculaire :323.88Tetrabenazine-d6
CAS :Tetrabenazine D6 is the deuterium-labeled Tetrabenazine. Tetrabenazine is a VMAT-inhibitor used for the treatment of hyperkinetic movement disorder.Formule :C19H27NO3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :323.46NBI-98782
CAS :NBI-98782 ((+)-α-DHTBZ) is an inhibtior of vesicular monoamine transporter (VMAT2) (Ki: 0.97 nM)Formule :C19H29NO3Degré de pureté :99.29%Couleur et forme :SolidMasse moléculaire :319.44Tetrabenazine Racemate
CAS :Tetrabenazine Racemate (Rubigen) is a selective and reversible inhibitor of vesicular monoamine transporter-2 (VMAT-2).Formule :C19H27NO3Degré de pureté :98.65% - 98.86%Couleur et forme :SolidMasse moléculaire :317.42Tetrabenazine methanesulfonate
CAS :Tetrabenazine methanesulfonate: ex-antipsychotic/therapy for movement disorders, blocks neurotransmitter uptake, labels vesicle transport.Formule :C20H31NO6SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :413.53Netarsudil free base
CAS :Netarsudil (AR-11324), a ROCK inhibitor, treats glaucoma by increasing eye outflow and lowering IOP, with mild hyperemia as a side effect.Formule :C28H27N3O3Couleur et forme :SolidMasse moléculaire :453.53Valbenazine
CAS :Valbenazine (NBI-98854), a highly selective vesicular monoamine transporter 2(VMAT2) inhibitor, is approved for the treatment of tardive dyskinesia.Formule :C24H38N2O4Degré de pureté :97.58%Couleur et forme :SolidMasse moléculaire :418.57Nisoxetine
CAS :Nisoxetine is a selective NET (noradrenaline transporter) inhibitor (Kd=0.76 nM) capable of blocking voltage-gated sodium channels.Formule :C17H21NO2Degré de pureté :98.71%Couleur et forme :SolidMasse moléculaire :271.35Decynium 22
CAS :Decynium 22 is a plasma membrane monoamine transporter (PMAT) inhibitorFormule :C23H23IN2Degré de pureté :99.92%Couleur et forme :Dark Red CrystalsMasse moléculaire :454.35FFN 511 hydrochloride
CAS :FFN 511 hydrochloride is a fluorescent pseudo-neurotransmitter (FFNs) targeting VMA T2 that can be used to label baraminergic nerve endings.Formule :C17H21ClN2O2Degré de pureté :99.83%Couleur et forme :SoildMasse moléculaire :320.81Talopram hydrochloride
CAS :noradrenalin transporter (NET) inhibitorFormule :C20H26ClNODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :331.88Indatraline
CAS :Indatraline is a nonselective monoamine transporter inhibitor.Formule :C16H15Cl2NCouleur et forme :SolidMasse moléculaire :292.2FFN200 dihydrochloride
CAS :FFN200 is a vesicular monoamine transporter 2 (VMAT2) substrate that selectively traces monoamine exocytosis in both neuronal cell culture and brain tissue.Formule :C11H14Cl2N2O2Couleur et forme :SolidMasse moléculaire :277.15Nisoxetine hydrochloride
CAS :Nisoxetine hydrochloride is a noradrenaline transporter (NET) inhibitorFormule :C17H21NO2·HClDegré de pureté :99.21%Couleur et forme :White SolidMasse moléculaire :307.82GZ-11608
CAS :GZ-11608, a selective and potent inhibitor of vesicular monoamine transporter-2 (VMAT2), presents a high affinity with a Ki value of 25 nM. It effectively reduces dopamine release induced by methamphetamine from isolated synaptic vesicles in brain dopaminergic neurons. GZ-11608 also demonstrates rapid penetration into the brain without exhibiting neurotoxicity, making it a valuable compound for researching methamphetamine use disorder [1].Formule :C19H25NOMasse moléculaire :283.41VMAT2-IN-I HCl
CAS :VMAT2-IN-I HCl is an inhibitor of vesicular monoamine transporter-2. It also has 15- fold greater affinity than GZ- 793A.Formule :C25H32ClF4NO4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :521.97Imipramine pamoate
CAS :Imipramine pamoate, a potent antidepressant [1] [2], is a chemical compound widely recognized for its efficacy in treating depressive disorders.Formule :C61H64N4O6Couleur et forme :SolidMasse moléculaire :949.18(2S,3S,11bR)-Dihydrotetrabenazine
CAS :(2S,3S,11bR)-Dihydrotetrabenazine ((2S,3S,11bR)-DHTBZ) is a highly selective inhibitor of vesicular monoamine transporter 2 (VMAT2) with a Ki value of 593 nM. It suppresses the vesicular transport of monoamine neurotransmitters, such as dopamine and serotonin, leading to reduced release into the synaptic cleft. This compound holds potential for research in Huntington's disease and other hyperkinetic movement disorders.Formule :C19H29NO3Couleur et forme :SolidMasse moléculaire :319.44Lafadofensine (D-(-)-Mandelic acid)
Lafadofensine D-(-)-Mandelic acid is a monoamines reuptake inhibitor with adequate effects when administered short-term.Formule :C32H32F2N2O6Couleur et forme :SolidMasse moléculaire :578.6Valbenazine tosylate
CAS :<p>Valbenazine tosylate, the tosylate salt of valbenazine, is a vesicular monoamine transporter 2 (VMAT2) inhibitor with a Ki value of 150 nM while displaying no</p>Formule :C38H54N2O10S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :762.973-Bromoamphetamine hydrochloride
CAS :3-Bromoamphetamine hydrochloride is a para-substituted amphetamine that functions as a monoamine releaser.Formule :C9H13BrClNCouleur et forme :SolidMasse moléculaire :250.563(+)-Tetrabenazine
CAS :(+)-Tetrabenazine ((3R,11bR)-Tetrabenazine) is a reversible vesicular monoamine transporter 2 (VMAT-2) inhibitor, inhibits transport by VMAT2 with 10-foldFormule :C19H27NO3Degré de pureté :98.69%Couleur et forme :SolidMasse moléculaire :317.42VMAT2-IN-2 tosylate
CAS :<p>VMAT2-IN-2 tosylate is a potent inhibitor of VMAT2 and is applicable in the research of tardive dyskinesia [1].</p>Formule :C27H36F3NO6SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :559.64
