Canal sodique
Les canaux sodiques sont des protéines membranaires essentielles qui permettent le passage des ions sodium (Na+) à travers la membrane cellulaire, générant et propageant des signaux électriques dans les neurones, les cellules musculaires et d'autres tissus excitables. Ces canaux sont vitaux pour l'initiation et la conduction des potentiels d'action, ce qui les rend cruciaux dans des processus tels que la transmission de l'influx nerveux, la contraction musculaire et la fonction cardiaque. La dysrégulation des canaux sodiques peut entraîner des troubles neurologiques, des arythmies et des conditions de douleur chronique. Chez CymitQuimica, nous proposons une variété de modulateurs de canaux sodiques pour soutenir vos recherches en neurobiologie, cardiologie et gestion de la douleur.
273 produits trouvés pour "Canal sodique".
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Nav1.8-IN-4
CAS :Nav1.8-IN-4 is a potent Nav1.8 channel inhibitor with potential analgesic activity.Nav1.8-IN-4 can be used for pain and neurological related disorders.Formule :C20H14F4N2O3Degré de pureté :99.97%Couleur et forme :SolidMasse moléculaire :406.33Ref: TM-T77693
1mg56,00€2mg80,00€5mg118,00€10mg178,00€25mg356,00€50mg580,00€100mg888,00€500mg1.783,00€Tocainide hydrochloride
CAS :Tocainide hydrochloride (2-amino-n-(2,6-dimethylphenyl)propanamide hydrochloride) is a sodium channel blocker.Formule :C11H17ClN2ODegré de pureté :97%Couleur et forme :SolidMasse moléculaire :228.72Benzocaine
CAS :Benzocaine is a surface anesthetic that acts by preventing transmission of impulses along nerve fibers and at nerve endings.Formule :C9H11NO2Degré de pureté :99.16% - 99.88%Couleur et forme :Rhombohedra From Ether DrypowderMasse moléculaire :165.19Topiramate
CAS :Topiramate (RWJ 17021) is a unique antiseizure medication that is used in the treatment of partial and generalized seizures.Formule :C12H21NO8SDegré de pureté :99.79% - 99.92%Couleur et forme :SolidMasse moléculaire :339.36Eleclazine hydrochloride
CAS :Eleclazine hydrochloride (GS 6615 hydrochloride) is a novel inhibitor of late Na+ current (IC50: 0.7 uM).Formule :C21H17ClF3N3O3Degré de pureté :99.86%Couleur et forme :SolidMasse moléculaire :451.83Ref: TM-T15207
1mg58,00€5mg110,00€1mL*10mM (DMSO)122,00€10mg166,00€25mg268,00€50mg403,00€100mg532,00€200mg705,00€Lamotrigine
CAS :Lamotrigine (BW430C) is an Anti-epileptic Agent and Mood Stabilizer.Formule :C9H7Cl2N5Degré de pureté :99.76% - 99.95%Couleur et forme :White SolidMasse moléculaire :256.09Lidocaine Hydrochloride hydrate
CAS :Lidocaine Hydrochloride hydrate is an amide local anesthetic, has anti-inflammatory property.Formule :C14H22N2O·HCl·H2ODegré de pureté :99.95%Couleur et forme :SolidMasse moléculaire :288.82Phenytoin sodium
CAS :Phenytoin sodium (Diphantoine) is an inactive stabilizer for voltage-gated sodium channel .Formule :C15H11N2NaO2Degré de pureté :99.88% - 99.92%Couleur et forme :SolidMasse moléculaire :274.25Mexiletine hydrochloride
CAS :Mexiletine hydrochloride is a lidocaine-like antiarrhythmic (Class IB) and anesthetic, stabilizing heartbeats by inhibiting sodium in cardiac cells.Formule :C11H18ClNODegré de pureté :99.88%Couleur et forme :SolidMasse moléculaire :215.72Oxcarbazepine
CAS :Oxcarbazepine (GP 47680), an anti-epileptic, reduces CNS disorganized electrical activity.Formule :C15H12N2O2Degré de pureté :98.46%Couleur et forme :White SolidMasse moléculaire :252.27Ref: TM-T0440
5mg34,00€1mL*10mM (DMSO)37,00€10mg50,00€25mg77,00€50mg96,00€100mg132,00€200mg171,00€500mg222,00€Dibucaine
CAS :Dibucaine (Cinchocaine), a local anesthetic of the amide type, is now usually used for surface anesthesia.Formule :C20H29N3O2Degré de pureté :99.69% - 99.88%Couleur et forme :White SolidMasse moléculaire :343.46Lidocaine
CAS :Lidocaine, an amide local anesthetic, reduces pain and inflammation by dampening ICAM-1, cytokines, and neutrophil influx.Formule :C14H22N2ODegré de pureté :99.88% - >99.99%Couleur et forme :White SolidMasse moléculaire :234.34DSP-2230
CAS :DSP-2230 is a selective blocker of Nav1.7/Nav1.8.Formule :C20H20F3N5O2Degré de pureté :97.14%Couleur et forme :SolidMasse moléculaire :419.4Ref: TM-T15174
1mg34,00€5mg66,00€1mL*10mM (DMSO)73,00€10mg99,00€25mg205,00€50mg334,00€100mg537,00€200mg762,00€Tocainide
CAS :Tocainide is a blocker of the sodium channel and used for the treatment of tinnitus.Formule :C11H16N2ODegré de pureté :99.84%Couleur et forme :SolidMasse moléculaire :192.26Vinpocetine
CAS :Vinpocetine (RGH-4405) is a selective inhibitor of cyclic GMP phosphodiesterase (PDE).Formule :C22H26N2O2Degré de pureté :99.85% - 99.98%Couleur et forme :White SolidMasse moléculaire :350.45Phenazopyridine hydrochloride
CAS :Phenazopyridine HCl, an oral urinary analgesic, may cause nausea, anemia, and liver/kidney toxicity. Possibly carcinogenic.Formule :C11H12ClN5Degré de pureté :99.27%Couleur et forme :SolidMasse moléculaire :249.7Propafenone
CAS :Propafenone: a drug for ventricular arrhythmias with mild beta-blocker activity, prolongs refractory period, and reduces heart automaticity.Formule :C21H27NO3Degré de pureté :99.02%Couleur et forme :SolidMasse moléculaire :341.44Ranolazine dihydrochloride
CAS :Ranolazine 2HCl, an antianginal, treats arrhythmia by inhibiting sodium current without changing blood pressure or heart rate.Formule :C24H35Cl2N3O4Degré de pureté :99.30% - >99.99%Couleur et forme :White Crystalline PowderMasse moléculaire :500.46Meticrane
CAS :Meticrane (Arresten) is a sulphonamide-derivative with thiazide-like diuretic activity.Formule :C10H13NO4S2Degré de pureté :99.16%Couleur et forme :SolidMasse moléculaire :275.34Amitriptyline hydrochloride
CAS :Amitriptyline hydrochloride (Annoyltin) is the hydrochloride salt of the tricyclic dibenzocycloheptadiene amitriptyline with antidepressant and antinociceptiveFormule :C20H24ClNDegré de pureté :99.39% - 99.94%Couleur et forme :SolidMasse moléculaire :313.86Mebeverine hydrochloride
CAS :Mebeverine hydrochloride (Colofac Hydrochloride), a β-phenylethylamine derivative, is a potent α1 repector inhibitor, relaxing the muscles in and around the gutFormule :C25H35NO5Degré de pureté :99.81% - 99.81%Couleur et forme :SolidMasse moléculaire :429.55Disopyramide
CAS :Disopyramide, or Triombrin, a class I anti-arrhythmic with membrane-stabilizing effects, has heart depressant, anticholinergic, and anesthetic properties.Formule :C21H29N3ODegré de pureté :99.62%Couleur et forme :White SolidMasse moléculaire :339.47E 0747 FA
E 0747 FA is an antiarrhythmic compound that inhibits the voltage of action potential Vmax in Purkinje fibers of porcine heart.E 0747 FA inhibits Na channels in cardiac cells.Formule :C22H30ClN3O6Degré de pureté :99.96%Couleur et forme :White SolidMasse moléculaire :467.94Amiloride hydrochloride
CAS :Amiloride hydrochloride (Amiloride HCl) 是上皮钠通道和尿激酶型纤溶酶原激活物受体的抑制剂，也是 polycystin-2通道阻断剂。Formule :C6H9Cl2N7ODegré de pureté :99.72% - 99.95%Couleur et forme :Physical Description Crystalline Solid Or Very Light Yellow Powder (Ntp 1992)Masse moléculaire :266.09Butamben
CAS :Butamben (Butyl 4-aminobenzoate) is a long-duration local anesthetic used for the treatment of chronic pain.Formule :C11H15NO2Degré de pureté :99.43%Couleur et forme :SolidMasse moléculaire :193.24Methocarbamol
CAS :Methocarbamol (AHR 85) is a centrally acting muscle relaxant whose mode of action has not been established.Formule :C11H15NO5Degré de pureté :99.96%Couleur et forme :White SolidMasse moléculaire :241.24Primidone
CAS :Primidone (NCI-C56360) is a potent anticonvulsant agent.Formule :C12H14N2O2Degré de pureté :99.9% - 99.91%Couleur et forme :SolidMasse moléculaire :218.25Brompheniramine maleate
CAS :Brompheniramine maleate (Dimotane) is an antagonist against histamine H1 receptors.Formule :C16H19BrN2·C4H4O4Degré de pureté :99.80%Couleur et forme :SolidMasse moléculaire :435.31QX-314 chloride
CAS :QX-314 chloride is a membrane-impermeable permanently charged blocker of sodium channel.Formule :C16H27ClN2ODegré de pureté :99.73%Couleur et forme :SolidMasse moléculaire :298.85Articaine hydrochloride
CAS :Articaine hydrochloride (Hoe-045) is a thiophene-containing local anesthetic pharmacologically similar to MEPIVACAINE.Formule :C13H21ClN2O3SDegré de pureté :99.76%Couleur et forme :SolidMasse moléculaire :320.84Phenytoin
CAS :Phenytoin: a non-sedative hydantoin, antiepileptic with anticonvulsant effects, stabilizes neurons, prevents seizure spread, and relaxes muscles.Formule :C15H12N2O2Degré de pureté :99.95%Couleur et forme :White SolidMasse moléculaire :252.27Nefopam hydrochloride
CAS :Nefopam hydrochloride (Nefopam HCl) is the hydrochloride salt form of nefopam, a centrally-acting, non-opioid benzoxazocine with analgesic activity.Formule :C17H20ClNODegré de pureté :99.32% - 99.85%Couleur et forme :White SolidMasse moléculaire :289.8Flunarizine dihydrochloride
CAS :Flunarizine dihydrochloride: a calcium blocker also targeting calmodulin and histamine H1, used for migraine, vertigo, vascular disease, and epilepsy aid.Formule :C26H28Cl2F2N2Degré de pureté :99.53% - 99.99%Couleur et forme :White SolidMasse moléculaire :477.42Ropivacaine
CAS :Ropivacaine (LEA-103 HCl) is a local anaesthetic drug belonging to the amino amide group.Formule :C17H26N2ODegré de pureté :97.75% - >99.99%Couleur et forme :SolidMasse moléculaire :274.40PF-04885614
CAS :PF-04885614 is a potent inhibitor of NaV1.8, has potential for neurological and neurodevelopmental diseases treatment.Formule :C13H14F3N3ODegré de pureté :98.02%Couleur et forme :SolidMasse moléculaire :285.27Ref: TM-T12421
2mg39,00€5mg60,00€1mL*10mM (DMSO)60,00€10mg96,00€25mg166,00€50mg299,00€100mg424,00€200mg595,00€Diphenidol hydrochloride
CAS :Diphenidol hydrochloride (Difenidol hydrochloride), a muscarinic antagonist, is employed as an anti-vertigo and as an antiemetic drug.Formule :C21H28ClNODegré de pureté :99.15% - 99.38%Couleur et forme :White SolidMasse moléculaire :345.91Ropivacaine hydrochloride
CAS :Ropivacaine hydrochloride (Ropivacaine monohydrochloride) is the hydrochloride salt of ropivacaine, a local anesthetic of the amide type with analgesic activityFormule :C17H26N2O·HClDegré de pureté :99.85% - 99.95%Couleur et forme :SolidMasse moléculaire :310.86Oxybuprocaine hydrochloride
CAS :Oxybuprocaine hydrochloride (Oxybuprocaine HCl), a local anesthetic, is used especially in otolaryngology and ophthalmology.Formule :C17H29ClN2O3Degré de pureté :>99.99%Couleur et forme :SolidMasse moléculaire :344.88Bupivacaine hydrochloride
CAS :Bupivacaine hydrochloride (Vivacaine) is a long-lasting, amide local anesthetic that blocks sodium channels, inhibiting nerve impulses and sensation.Formule :C18H28N2O·HClDegré de pureté :99.89% - 99.9%Couleur et forme :White SolidMasse moléculaire :324.89NaV1.7 inhibitor-1
CAS :NaV1.7 inhibitor-1, an efficacious inhibitor of voltage-gated sodium channel (NaV) 1.7 (IC50 of 0.6 nM for hNaV1.7).Formule :C23H30FNO4SDegré de pureté :99.89%Couleur et forme :SolidMasse moléculaire :435.55Ref: TM-T12181
1mg99,00€5mg241,00€1mL*10mM (DMSO)265,00€10mg385,00€25mg663,00€50mg888,00€100mg1.305,00€Lidocaine hydrochloride
CAS :Lidocaine HCl: local anesthetic, antiarrhythmic, stronger & longer-lasting than procaine but shorter than bupivacaine/prilocaine.Formule :C14H23ClN2ODegré de pureté :99.83% - 99.92%Couleur et forme :SolidMasse moléculaire :270.798Ceratotoxin-1
Ceratotoxin-1 (CcoTx1) is a peptide toxin that functions as an inhibitor of various voltage-gated sodium channel subtypes.Formule :C172H256N52O50S6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :4044.58XPC-7724
XPC-7724 is a selective inhibitor of the Nav1.6 channel, with an IC50 value of 0.078 μM. It is useful in research related to neurological disorders.Formule :C25H30FN5O2SMasse moléculaire :483.21042OD1
Activates rat Nav1.7, human Nav1.4, rat Nav1.6 (EC50: 7, 10, 47 nM); minimal on Nav1.2, 1.3, 1.5 (EC50 >3 μM); blocks fast inactivation; triggers pain.Formule :C308H466N90O95S8Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :7206.11-(1-Methyl-1h-pyrazol-4-yl)-ethanone
CAS :1-(1-Methyl-1h-pyrazol-4-yl)-ethanone is a high purity biochemical reagent that can be used in research related to life sciences.Formule :C6H8N2ODegré de pureté :99.92%Couleur et forme :SolidMasse moléculaire :124.14Sodium Channel Targeted Library
A unique collection of xnum sodium channel blockers and agonists for high throughput and high content screening;Couleur et forme :Odour SolidRef: TM-L7400
1mgÀ demander10μL*10mM (DMSO)À demander20μL*10mM (DMSO)À demander30μL*10mM (DMSO)À demander50μL*10mM (DMSO)À demander100μL*10mM (DMSO)À demander250μL*10mM (DMSO)À demanderSodium Channel inhibitor 5
Sodium Channel inhibitor5 (compound 7d) is a potent sodium channel inhibitor with an IC50 of 2.7 μM, playing a significant role in antiarrhythmic research.Formule :C24H23F3N4O2Couleur et forme :SolidMasse moléculaire :456.17731Nav1.8-IN-6
Nav1.8-IN-6 (Compound 2j) is a novel pyridinone amide Nav1.8 channel inhibitor with IC50 values of 513.33 nM in the resting state and 471.81 nM in the partially activated state. Nav1.8-IN-6 also exhibits analgesic activity.Formule :C19H17F6N3O2Couleur et forme :SolidMasse moléculaire :433.1225GpTx-1
CAS :GpTx-1 exhibits potent selectivity as a NaV1.7 antagonist, demonstrating an inhibition concentration (IC50) of 10 nM [1].Formule :C176H271N53O45S7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :4073.82Phrixotoxin 3
CAS :Potent NaV blocker: IC50 - 0.6 nM (NaV1.2), 42 nM (NaV1.3), 72 nM (NaV1.5); voltage-dependent inhibition.Formule :C176H269N51O48S6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :4059.74
