Canal calcique
Les canaux calciques sont des protéines membranaires qui régulent le flux d'ions calcium dans et hors des cellules, ce qui est essentiel pour diverses fonctions cellulaires, y compris la contraction musculaire, la libération de neurotransmetteurs et l'expression génique. La dysrégulation de l'activité des canaux calciques est associée à des conditions telles que l'hypertension, les arythmies cardiaques et les troubles neurologiques. Chez CymitQuimica, nous proposons une large sélection de modulateurs des canaux calciques pour soutenir vos recherches en santé cardiovasculaire, neurobiologie et transduction du signal.
573 produits trouvés pour "Canal calcique"
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Huwentoxin I
CAS :Huwentoxin I (HWTX-I) is a peptide toxin that targets and inhibits both voltage-gated sodium channels and N-type calcium channels.Formule :C161H246N48O44S6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :3750.36Mipsagargin
CAS :Mipsagargin (G-202) is a new antibiotic that inhibits DNA biosynthesis.Formule :C66H100N6O27Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1409.52Nesiritide acetate
CAS :Nesiritide, a 32-amino acid natriuretic peptide and recombinant form of human brain natriuretic peptide, enhances vasorelaxation ex vivo in porcine hearts from an acute coronary occlusion model when given as a 2 µg/kg bolus dose followed by a 0.01 µg/kg per minute infusion, facilitated by the calcium ionophore A23187. Formulations containing nesiritide have been utilized in managing congestive heart failure.Formule :C143H244N50O42S4C2H4O2Couleur et forme :SolidMasse moléculaire :3524.1Cyclic ADP-ribose ammonium
cADPR ammonium is a second messenger that boosts cytosolic calcium via Ryanodine receptors and TRPM2 channels.Couleur et forme :LiquidChlorocresol
CAS :Chlorocresol (4-Chloro-3-methylphenol) is an antiseptic medication.Formule :C7H7ClOCouleur et forme :SolidMasse moléculaire :142.58ω-Agatoxin TK
CAS :Selective blocker of CaV2.1 P/Q-type calcium channels.Formule :C215H337N65O70S10Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :5273.02PACAP-38 (31-38), human, mouse, rat
CAS :PACAP-38 (31-38), human, mouse, rat demonstrates potent, efficacious, and sustained stimulatory effects on sympathetic neuronal NPY and catecholamine productionFormule :C47H83N17O11Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1062.27Candidalysin
CAS :Candidalysin is a cytolytic peptide toxin initially isolated from *Candida albicans*, exhibiting both toxic and non-toxic properties. It activates epithelial cell signaling pathways by interacting with the epithelial growth factor receptor (EGFR) on host cells, leading to the activation of matrix metalloproteinases (MMP) and calcium ion influx, which results in inflammatory responses and immune cell recruitment. Additionally, Candidalysin exhibits cytotoxicity by causing membrane damage to host cells.Formule :C153H266N38O38S2Couleur et forme :SolidMasse moléculaire :3310.11sFTX-3.3
CAS :sFTX-3.3 is a calcium ion channel antagonist, exhibiting IC50 values of approximately 0.24 mM and 0.70 mM against P-type and N-type channels respectively.Formule :C12H29N7OCouleur et forme :SolidMasse moléculaire :287.412MMK 1
CAS :Potent hFPR2 agonist; EC50: 1 nM (mFPR2), 2 nM (hFPR2), >10,000 nM (hFPR1). Induces monocyte/neutrophil migration, boosts IL-1β/IL-6, activates NADPH-oxidase.Formule :C75H123N19O18SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :1610.97Katacalcin
CAS :Katacalcin (PDN 21) is a potent plasma calcium-lowering peptide[1].Formule :C97H154N34O36S2Degré de pureté :98%Couleur et forme :White PowderMasse moléculaire :2436.6Kurtoxin
Kurtoxin is a selective Cav3 (T-type) voltage-gated Ca2+ channel gating inhibitor, exhibiting a dissociation constant (Kd) of 15 nM for the Cav3.1 (α1G T-type)Formule :C324H478N94O90S8Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :7386.36SG-094
CAS :SG-094 inhibits TPC2, halts RIL175 cell growth, IC50: 3.7 μM for cancer research.
Formule :C30H29NO3Degré de pureté :97.06%Couleur et forme :SoildMasse moléculaire :451.56(±)5(6)-DiHETE
CAS :Eicosapentaenoic acid is an ω-3 polyunsaturated fatty acid that is abundant in marine organisms and fish oils.Formule :C20H32O4Couleur et forme :SolidMasse moléculaire :336.472Sulcardine 2HCl
CAS :Sulcardine 2HCl is a multi-ion channel blocker that blocks the properties of hERG and hNav1.5 channels and can be used to study atrial fibrillation.Formule :C24H35Cl2N3O4SDegré de pureté :99.33% - 99.76%Couleur et forme :SoildMasse moléculaire :532.523Ethacrynic acid D5
CAS :Ethacrynic acid: a diuretic, anti-inflammatory, inhibits calcium channels, GSTs, NF-kB pathway, and modulates leukotriene; has deuterium-labeled form.Formule :C13H12Cl2O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :308.17ω-Conotoxin GVIA
CAS :Peptide neurotoxin; selectively and reversibly blocks N-type calcium channels (IC50 = 0.15 nM). Reduces (RS)-3,5-DHPG -induced long term depression in vivo.Formule :C120H182N38O43S6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :3037UK-59811 hydrochloride
CAS :UK-59811 hydrochloride, Br-dihydropyridine derivative, blocks Ca V Ab channels in bacteria, IC50: 194 nM.Formule :C22H30BrClN2O5Couleur et forme :SolidMasse moléculaire :517.85Ziconotide
CAS :Ziconotide: analgesic from cone snail for severe, chronic pain; synthetic ω-conotoxin.Formule :C102H172N36O32S7Degré de pureté :98%Couleur et forme :White PowderMasse moléculaire :2639.131-(aminomethyl)cyclopropanecarboxylic acid hydrochloride
CAS :1-(aminomethyl)cyclopropanecarboxylic acid hydrochloride inhibits L amino acid transporter proteins and the α2δ subunit of voltage-gated calcium channels.1-(
Formule :C5H10ClNO2Degré de pureté :>99.99%Couleur et forme :SolidMasse moléculaire :151.59
